首页 > 最新文献

Journal of Health Specialties最新文献

英文 中文
An investigation of the saudi healthcare system's readiness for change in the light of vision 2030: The role of transformational leadership style 调查沙特卫生保健系统的准备在愿景2030光的变化:变革的领导风格的作用
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_142_17
M. Alharbi
Objectives: Organisational change is among the major challenges that face healthcare organisations, and many factors affect their ability to be ready to adopt the change desired. Among these important factors are the significant role of the attitude of the leadership that is responsible for the change. This empirical study was conducted to examine the role and contribution of the transformational leadership style to the readiness for change in healthcare organisations in Saudi Arabia. Materials and Methods: Primary data were collected from a sample of 83 middle managers in the hospitals in the Al-Qassim region in the Kingdom of Saudi Arabia. The study used a self-administered questionnaire to examine the role of transformational leadership in the readiness for change in healthcare organisations. Cross-sectional data were analysed using SPSS. Results: A positive and significant relation was found between transformational leadership and the readiness for change with 30% variation in the dependent variable (R2 = 0.30). Conclusions: This study is valuable for healthcare policymakers and providers, as it offers information about the leadership behaviours desired in readiness for change that have the potential to influence the intentions, attitudes and beliefs of members of healthcare organisations that help them accept and understand a change initiative.
目标:组织变革是医疗保健组织面临的主要挑战之一,许多因素影响他们准备采用所需变革的能力。在这些重要因素中,领导态度的重要作用是负责变革的。本实证研究进行了检查的作用和变革的领导风格的贡献,以准备在沙特阿拉伯医疗机构的变化。材料和方法:从沙特阿拉伯王国Al-Qassim地区医院的83名中层管理人员样本中收集初步数据。该研究使用了一份自我管理的问卷调查,以检查变革型领导在医疗机构变革准备中的作用。横截面数据采用SPSS进行分析。结果:变革型领导与变革准备之间存在显著的正相关关系,因变量变异率为30% (R2 = 0.30)。结论:这项研究对医疗保健政策制定者和提供者是有价值的,因为它提供了关于准备变革所需的领导行为的信息,这些行为有可能影响医疗保健组织成员的意图、态度和信念,帮助他们接受和理解变革倡议。
{"title":"An investigation of the saudi healthcare system's readiness for change in the light of vision 2030: The role of transformational leadership style","authors":"M. Alharbi","doi":"10.4103/JHS.JHS_142_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_142_17","url":null,"abstract":"Objectives: Organisational change is among the major challenges that face healthcare organisations, and many factors affect their ability to be ready to adopt the change desired. Among these important factors are the significant role of the attitude of the leadership that is responsible for the change. This empirical study was conducted to examine the role and contribution of the transformational leadership style to the readiness for change in healthcare organisations in Saudi Arabia. Materials and Methods: Primary data were collected from a sample of 83 middle managers in the hospitals in the Al-Qassim region in the Kingdom of Saudi Arabia. The study used a self-administered questionnaire to examine the role of transformational leadership in the readiness for change in healthcare organisations. Cross-sectional data were analysed using SPSS. Results: A positive and significant relation was found between transformational leadership and the readiness for change with 30% variation in the dependent variable (R2 = 0.30). Conclusions: This study is valuable for healthcare policymakers and providers, as it offers information about the leadership behaviours desired in readiness for change that have the potential to influence the intentions, attitudes and beliefs of members of healthcare organisations that help them accept and understand a change initiative.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"45 1","pages":"45 - 51"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80011178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
A rare case of suicide attempt by subcutaneous self-injection of kerosene: A case report and review of literature 皮下自注射煤油企图自杀一例罕见病例报告及文献复习
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_156_17
F. Alquraish, M. Aldossary, A. AlMuhsin, Omar Alkhlaiwy, A. Alghamdi
Kerosene is one of the most widely used sources of energy in developing countries. Modes of accidental exposure include inhalation, ingestion and through skin or eye contact. There have been few cases reported in literature where kerosene was injected intravenously and subcutaneously with differing outcomes ranging from mild irritation to serious necrotising fasciitis. It remains challenging to predict the outcome of patients who inject kerosene through a non-venous route as it is difficult to establish the accuracy of tissue layer affected by the injection. The aim of this study is to analyse all the case studies presented with attempt of suicide by self-injection of kerosene, to establish a method of management available in this rare presentation.
煤油是发展中国家最广泛使用的能源之一。意外接触方式包括吸入、摄入和通过皮肤或眼睛接触。文献中很少有煤油静脉注射和皮下注射的病例报道,其结果不同,从轻度刺激到严重的坏死性筋膜炎。预测通过非静脉途径注射煤油的患者的结果仍然具有挑战性,因为很难确定受注射影响的组织层的准确性。本研究的目的是分析所有的案例研究提出的企图自杀的自我注射煤油,建立一种管理方法,可在这种罕见的表现。
{"title":"A rare case of suicide attempt by subcutaneous self-injection of kerosene: A case report and review of literature","authors":"F. Alquraish, M. Aldossary, A. AlMuhsin, Omar Alkhlaiwy, A. Alghamdi","doi":"10.4103/JHS.JHS_156_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_156_17","url":null,"abstract":"Kerosene is one of the most widely used sources of energy in developing countries. Modes of accidental exposure include inhalation, ingestion and through skin or eye contact. There have been few cases reported in literature where kerosene was injected intravenously and subcutaneously with differing outcomes ranging from mild irritation to serious necrotising fasciitis. It remains challenging to predict the outcome of patients who inject kerosene through a non-venous route as it is difficult to establish the accuracy of tissue layer affected by the injection. The aim of this study is to analyse all the case studies presented with attempt of suicide by self-injection of kerosene, to establish a method of management available in this rare presentation.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"14 1","pages":"91 - 94"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81696972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Palliative sedation and ethical dilemma 姑息性镇静与伦理困境
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_21_18
Juri Salamah, S. Alshammary, Stuart Brown
Palliative sedation is a unique concern for the patient as well as the family. It is a difficult serious ethical dilemma for the physicians to handle. The conflicting ethical principles of autonomy, beneficence and nonmaleficence in continuing versus discontinuing all supportive devices raise concerns among health professionals whether this is euthanasia (physician-assisted suicide) or is just prolonging the patient's unnecessary suffering.
姑息性镇静是一个独特的关心病人以及家属。对于医生来说,这是一个难以处理的严重的伦理困境。在继续或停止使用所有支持设备时,自主、有益和无害的伦理原则相互冲突,这引起了卫生专业人员的关注,这是安乐死(医生协助自杀),还是只是延长了病人不必要的痛苦。
{"title":"Palliative sedation and ethical dilemma","authors":"Juri Salamah, S. Alshammary, Stuart Brown","doi":"10.4103/JHS.JHS_21_18","DOIUrl":"https://doi.org/10.4103/JHS.JHS_21_18","url":null,"abstract":"Palliative sedation is a unique concern for the patient as well as the family. It is a difficult serious ethical dilemma for the physicians to handle. The conflicting ethical principles of autonomy, beneficence and nonmaleficence in continuing versus discontinuing all supportive devices raise concerns among health professionals whether this is euthanasia (physician-assisted suicide) or is just prolonging the patient's unnecessary suffering.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"34 1","pages":"87 - 90"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87446024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the evolution and level of evidence of spine surgery research in Saudi Arabia 评估沙特阿拉伯脊柱外科研究的进展和证据水平
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_129_17
Saleh Salem Baeesa, Yazid Maghrabi, S. Bajoh, Suhail Bajammal
Objectives: To measure the impact of Saudi publications on global spine surgery literature, to evaluate the quality of these papers by measuring the level of evidence (LOE) and then to compare it with similar international studies done on the topic of spine surgery. Materials and Methods: The study design was a systematic review, where a systemic online search using PubMed, Google Scholar and Embase was carried out using search terms related to spine surgery. The impact of each article was measured by the citation number and was reviewed by Oxford Centre for Evidence-Based Medicine LOE scale. Results: We identified 128 articles that met the inclusion criteria, of which 58% were Level IV studies. The most common study design was case reports (45%). We compared our study with the similar or different methodology of international studies for spine surgery research. Conclusion: This first study, for the analysis of spine surgery literature in Saudi Arabia, shows that Saudi publications in spine surgery have little impact on the global spine surgery research. The LOE was low and that there is insignificant change throughout 25 years. A national multicentre or international collaborative research is recommended to produce high LOE research.
目的:测量沙特出版物对全球脊柱外科文献的影响,通过测量证据水平(LOE)来评估这些论文的质量,然后将其与脊柱外科主题的类似国际研究进行比较。材料和方法:本研究设计为系统评价,使用PubMed、Google Scholar和Embase进行系统的在线搜索,使用与脊柱外科相关的搜索词。每篇文章的影响力通过引用数来衡量,并通过牛津循证医学中心LOE量表进行评估。结果:我们确定了128篇符合纳入标准的文章,其中58%为IV级研究。最常见的研究设计是病例报告(45%)。我们将本研究与国际脊柱外科研究相似或不同的研究方法进行了比较。结论:本研究首先对沙特阿拉伯的脊柱外科文献进行分析,发现沙特在脊柱外科方面的出版物对全球脊柱外科研究的影响不大。在25年的时间里,LOE较低,变化不显著。建议进行国家多中心或国际合作研究,以产生高LOE研究。
{"title":"Assessing the evolution and level of evidence of spine surgery research in Saudi Arabia","authors":"Saleh Salem Baeesa, Yazid Maghrabi, S. Bajoh, Suhail Bajammal","doi":"10.4103/JHS.JHS_129_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_129_17","url":null,"abstract":"Objectives: To measure the impact of Saudi publications on global spine surgery literature, to evaluate the quality of these papers by measuring the level of evidence (LOE) and then to compare it with similar international studies done on the topic of spine surgery. Materials and Methods: The study design was a systematic review, where a systemic online search using PubMed, Google Scholar and Embase was carried out using search terms related to spine surgery. The impact of each article was measured by the citation number and was reviewed by Oxford Centre for Evidence-Based Medicine LOE scale. Results: We identified 128 articles that met the inclusion criteria, of which 58% were Level IV studies. The most common study design was case reports (45%). We compared our study with the similar or different methodology of international studies for spine surgery research. Conclusion: This first study, for the analysis of spine surgery literature in Saudi Arabia, shows that Saudi publications in spine surgery have little impact on the global spine surgery research. The LOE was low and that there is insignificant change throughout 25 years. A national multicentre or international collaborative research is recommended to produce high LOE research.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"82 1","pages":"52 - 59"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83752834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Herbal medicine use by Saudi patients with chronic diseases: A cross-sectional study (experience from Southern Region of Saudi Arabia) 沙特慢性病患者使用草药:一项横断面研究(来自沙特阿拉伯南部地区的经验)
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_157_17
M. Alghamdi, A. A. A Mohammed, Fahad Alfahaid, Ali Albshabshe
Background: Herbal medicine use has become a popular treatment among patients with chronic diseases worldwide. Many patients with chronic illnesses use herbal medicine without consulting their healthcare professionals. Therefore, the primary aim of this study was to determine the frequency and correlates of herbal medicine use in Saudi patients with chronic diseases. The secondary aim was to explore how frequent patients with chronic illnesses consult their healthcare professionals for concomitant use of conventional treatment and herbal medicine. Materials and Method: A cross-sectional study conducted from December 2014 to January 2015 at King Abdullah General Hospital in Bisha. Adults aged > 18 years with chronic illnesses were enrolled in the study. The survey data form included demographic data and types of herbal medicines. Multivariate logistic regression was used to explore the effect of different factors promoting the use of herbal medicine. Results: Of the 235 patients who completed the data form, the prevalence of herbal medicine users was (67.65%), with Trigonella foenum-graecum (32.7%), Pimpinella anisum (19.49%), Nigella sativa (17.61%), Green tea (13.83%) and Peganum (5.66%) as the most frequently used. Nearly 88.67% of herb users did not consult their healthcare professionals. Almost 90.56% of healthcare professionals did not respond to herbs users' questions about herbal medicine. Patients with increased age and living in the urban area are likely to use herbal medicine with odds ratio (OR): 4.12, 95% confidence interval (CI): 1.94–8.74 and OR: 109.20, 95% CI: 31.88–374.02, respectively. Conclusion: This study revealed a high prevalence of herbal medicine use among patients with chronic diseases. More awareness and education about risks and complications of herbal medicine use are needed for both patients and healthcare professionals.
背景:在世界范围内,草药治疗已成为慢性病患者的一种流行治疗方法。许多患有慢性疾病的患者在没有咨询他们的医疗保健专业人员的情况下使用草药。因此,本研究的主要目的是确定沙特慢性疾病患者使用草药的频率和相关因素。第二个目的是探讨慢性疾病患者咨询医疗保健专业人员同时使用常规治疗和草药的频率。材料与方法:2014年12月至2015年1月在比沙阿卜杜拉国王总医院进行的横断面研究。研究对象为18岁以上患有慢性疾病的成年人。调查数据表包括人口统计数据和草药种类。采用多因素logistic回归探讨不同因素对中药使用的影响。结果:在填写资料表的235例患者中,使用中草药的比例为67.65%,其中使用频率最高的是葫芦巴(32.7%)、茴香(19.49%)、黑草(17.61%)、绿茶(13.83%)和槟榔(5.66%)。近88.67%的草药使用者没有咨询他们的医疗保健专业人员。近90.56%的医疗保健专业人员没有回答草药使用者关于草药的问题。年龄增大和居住在城市地区的患者更倾向于使用草药,优势比(OR)为4.12,95%可信区间(CI)为1.94 ~ 8.74;OR为109.20,95% CI为31.88 ~ 374.02。结论:本研究揭示了慢性疾病患者中草药使用的高发性。患者和医疗保健专业人员都需要提高对使用草药的风险和并发症的认识和教育。
{"title":"Herbal medicine use by Saudi patients with chronic diseases: A cross-sectional study (experience from Southern Region of Saudi Arabia)","authors":"M. Alghamdi, A. A. A Mohammed, Fahad Alfahaid, Ali Albshabshe","doi":"10.4103/JHS.JHS_157_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_157_17","url":null,"abstract":"Background: Herbal medicine use has become a popular treatment among patients with chronic diseases worldwide. Many patients with chronic illnesses use herbal medicine without consulting their healthcare professionals. Therefore, the primary aim of this study was to determine the frequency and correlates of herbal medicine use in Saudi patients with chronic diseases. The secondary aim was to explore how frequent patients with chronic illnesses consult their healthcare professionals for concomitant use of conventional treatment and herbal medicine. Materials and Method: A cross-sectional study conducted from December 2014 to January 2015 at King Abdullah General Hospital in Bisha. Adults aged > 18 years with chronic illnesses were enrolled in the study. The survey data form included demographic data and types of herbal medicines. Multivariate logistic regression was used to explore the effect of different factors promoting the use of herbal medicine. Results: Of the 235 patients who completed the data form, the prevalence of herbal medicine users was (67.65%), with Trigonella foenum-graecum (32.7%), Pimpinella anisum (19.49%), Nigella sativa (17.61%), Green tea (13.83%) and Peganum (5.66%) as the most frequently used. Nearly 88.67% of herb users did not consult their healthcare professionals. Almost 90.56% of healthcare professionals did not respond to herbs users' questions about herbal medicine. Patients with increased age and living in the urban area are likely to use herbal medicine with odds ratio (OR): 4.12, 95% confidence interval (CI): 1.94–8.74 and OR: 109.20, 95% CI: 31.88–374.02, respectively. Conclusion: This study revealed a high prevalence of herbal medicine use among patients with chronic diseases. More awareness and education about risks and complications of herbal medicine use are needed for both patients and healthcare professionals.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"1 1","pages":"77 - 81"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83527675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Attitudes and perceptions towards organ donation in Riyadh 利雅得对器官捐赠的态度和看法
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_153_17
Basil Alhussain, B. Alasmari, A. Omair, I. Altraif, Abdulrahman R Altamimi
Context: Organ donation is an optimal solution for patients with certain conditions who benefit from transplantation such as liver cirrhosis. The organs come from living and brain-dead donors, who opt to donate parts of their bodies to treat others. This serves to treat and improve the outcome to those in need; however, the awareness in this regard is unclear. Aims: This study aimed to assess the attitude and perceptions towards organ donation and the concept of brain death in the population of Riyadh, Saudi Arabia. Settings and Design: A cross-sectional quantitative design was used. The study was conducted at four large malls in different geographical areas. Data collection was done at random times during the day. Subjects and Methods: A self-administered questionnaire was designed to examine the sociodemographic data. A 4-item questionnaire was developed to assess the attitude and perception of organ donation and brain death. Statistical Analysis Used: Data were entered and analysed using SPSS v21. Descriptive statistics are presented as frequencies and percentages for the categorical variables and mean ± standard deviation for numerical variables. Results: The study included 409 participants from different sociodemographic backgrounds. Over 60% were able to identify the correct definition of brain death and 68.1% stated that they would like to donate their organs in case of brain death. Conclusions: Our findings suggest that the population has an acceptable understanding of the concept of brain death and that they are willing to donate in cases of brain death. It also shows an excellent understanding of the religious aspect, but with poor family and friends' communication regarding the subject.
背景:器官捐献对于某些从移植中获益的患者,如肝硬化,是一个最佳的解决方案。这些器官来自活体和脑死亡捐赠者,他们选择捐献自己身体的一部分来治疗他人。这有助于治疗和改善有需要的人的结果;然而,这方面的意识尚不清楚。目的:本研究旨在评估沙特阿拉伯利雅得人口对器官捐赠和脑死亡概念的态度和看法。环境与设计:采用横断面定量设计。这项研究是在不同地理区域的四个大型购物中心进行的。数据收集是在白天的随机时间进行的。研究对象和方法:设计了一份自我管理的问卷来检查社会人口统计数据。制定了一份包含4个项目的调查问卷,以评估器官捐赠和脑死亡的态度和看法。使用统计分析:使用SPSS v21进行数据录入和分析。描述性统计以频率和百分比表示分类变量和平均值±标准差表示数值变量。结果:本研究包括409名来自不同社会人口背景的参与者。超过60%的人能够确定脑死亡的正确定义,68.1%的人表示他们愿意在脑死亡时捐献器官。结论:我们的研究结果表明,人们对脑死亡的概念有一个可接受的理解,并且他们愿意在脑死亡的情况下捐赠。它也显示了对宗教方面的出色理解,但与家人和朋友在这个问题上的沟通很差。
{"title":"Attitudes and perceptions towards organ donation in Riyadh","authors":"Basil Alhussain, B. Alasmari, A. Omair, I. Altraif, Abdulrahman R Altamimi","doi":"10.4103/JHS.JHS_153_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_153_17","url":null,"abstract":"Context: Organ donation is an optimal solution for patients with certain conditions who benefit from transplantation such as liver cirrhosis. The organs come from living and brain-dead donors, who opt to donate parts of their bodies to treat others. This serves to treat and improve the outcome to those in need; however, the awareness in this regard is unclear. Aims: This study aimed to assess the attitude and perceptions towards organ donation and the concept of brain death in the population of Riyadh, Saudi Arabia. Settings and Design: A cross-sectional quantitative design was used. The study was conducted at four large malls in different geographical areas. Data collection was done at random times during the day. Subjects and Methods: A self-administered questionnaire was designed to examine the sociodemographic data. A 4-item questionnaire was developed to assess the attitude and perception of organ donation and brain death. Statistical Analysis Used: Data were entered and analysed using SPSS v21. Descriptive statistics are presented as frequencies and percentages for the categorical variables and mean ± standard deviation for numerical variables. Results: The study included 409 participants from different sociodemographic backgrounds. Over 60% were able to identify the correct definition of brain death and 68.1% stated that they would like to donate their organs in case of brain death. Conclusions: Our findings suggest that the population has an acceptable understanding of the concept of brain death and that they are willing to donate in cases of brain death. It also shows an excellent understanding of the religious aspect, but with poor family and friends' communication regarding the subject.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"23 1","pages":"68 - 71"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80096350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Stability testing of extemporaneous preparation of methyl salicylate ointment 临时制备水杨酸甲酯软膏的稳定性试验
Pub Date : 2018-04-01 DOI: 10.4103/JHS.JHS_14_18
H. Makeen, S. Pancholi, H. Alhazmi, A. Ezzi, A. A Hazzazi, A. Meraya
Background: Pharmacist in community pharmacy, hospital or nursing home may be left with only option of preparing extemporaneous formulation using traditional compounding techniques when none of the available commercial dosage forms is appropriate to meet the special needs of some special patients. It is essential to make available safe, effective and stable drug formulation that is well-tolerated by the patient of particular age and condition, but the biggest concern is quality, particularly the stability of extemporaneous preparations which are not subjected to testing like a product approved for market. Unavailability of stability data limits the availability of many medicines for special patients. Aim: The dermatological formulations constitute a large proportion of extemporaneously compounded drugs and condition at which such extemporaneous products shall be stored to maintain the quality of product until use needs to be determined. This research was undertaken to carry out the stability testing of extemporaneous methyl salicylate ointment to determine the shelf life. Materials and Methods: Methyl salicylate analgesic ointment prepared extemporaneously as per extemporaneous preparation manual of King Fahad Central Hospital, Jazan, was subjected to stability study at 25°C ± 5°C and 2°C–8°C for 120 days. Results: The shelf life (t90%) of extemporaneously prepared methyl salicylate ointment was found to be 131 days at room temperature (25°C ± 5°C) and 176 days in the refrigerator (2°C–8°C). Conclusion: The methyl salicylate present in extemporaneous ointment preparation is fairly stable at cool temperatures but shows faster degradation at higher temperature conditions. Therefore, it is recommended that an expiry date of 4 months can be safely mentioned when stored in cool.
背景:社区药房、医院或养老院的药剂师在现有的商业剂型都不能满足某些特殊患者的特殊需要时,可能只能选择使用传统的配制技术配制临时制剂。至关重要的是提供安全、有效和稳定的药物配方,并为特定年龄和病情的患者提供良好的耐受性,但最大的问题是质量,特别是不像批准上市的产品那样经过检测的临时制剂的稳定性。稳定性数据的缺乏限制了许多特殊患者药物的可得性。目的:皮肤科制剂在临时配制药品中占很大比例,临时配制药品应在何种条件下保存,以保持产品质量,直至确定使用。本研究旨在对即食水杨酸甲酯软膏进行稳定性试验,以确定其保质期。材料与方法:根据吉赞法赫德国王中心医院临时配制手册,临时配制水杨酸甲酯镇痛软膏,在25°C±5°C和2°C - 8°C条件下进行稳定性研究,持续120天。结果:即制水杨酸甲酯软膏在室温(25°C±5°C)下的保质期为131天,在冰箱(2°C - 8°C)下的保质期为176天(t90%)。结论:即食软膏制剂中水杨酸甲酯在低温条件下相当稳定,但在高温条件下降解速度较快。因此,建议在冷藏时可以安全地提到4个月的有效期。
{"title":"Stability testing of extemporaneous preparation of methyl salicylate ointment","authors":"H. Makeen, S. Pancholi, H. Alhazmi, A. Ezzi, A. A Hazzazi, A. Meraya","doi":"10.4103/JHS.JHS_14_18","DOIUrl":"https://doi.org/10.4103/JHS.JHS_14_18","url":null,"abstract":"Background: Pharmacist in community pharmacy, hospital or nursing home may be left with only option of preparing extemporaneous formulation using traditional compounding techniques when none of the available commercial dosage forms is appropriate to meet the special needs of some special patients. It is essential to make available safe, effective and stable drug formulation that is well-tolerated by the patient of particular age and condition, but the biggest concern is quality, particularly the stability of extemporaneous preparations which are not subjected to testing like a product approved for market. Unavailability of stability data limits the availability of many medicines for special patients. Aim: The dermatological formulations constitute a large proportion of extemporaneously compounded drugs and condition at which such extemporaneous products shall be stored to maintain the quality of product until use needs to be determined. This research was undertaken to carry out the stability testing of extemporaneous methyl salicylate ointment to determine the shelf life. Materials and Methods: Methyl salicylate analgesic ointment prepared extemporaneously as per extemporaneous preparation manual of King Fahad Central Hospital, Jazan, was subjected to stability study at 25°C ± 5°C and 2°C–8°C for 120 days. Results: The shelf life (t90%) of extemporaneously prepared methyl salicylate ointment was found to be 131 days at room temperature (25°C ± 5°C) and 176 days in the refrigerator (2°C–8°C). Conclusion: The methyl salicylate present in extemporaneous ointment preparation is fairly stable at cool temperatures but shows faster degradation at higher temperature conditions. Therefore, it is recommended that an expiry date of 4 months can be safely mentioned when stored in cool.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"8 1","pages":"72 - 76"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77166667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Co-Morbidities in psoriatic versus non-psoriatic patients 银屑病患者与非银屑病患者的合并症
Pub Date : 2018-04-01 DOI: 10.4103/jhs.JHS_89_17
Rana Al Houssien, A. Al sheikh
Background: Psoriasis is a chronic dermatological disorder which involves inflammatory and immune mechanisms. It affects the outer surfaces of the body including skin, hair and nails. It has been related to extracutaneous manifestations and systemic disorders. The aim of this study is to compare the chronic illnesses, including diabetes, hypertension, dyslipidaemia, hypothyroidism and abnormal renal and liver profiles, among patients with psoriasis and patients who had appendectomy. Methods: A case–control study took a place in Riyadh. It included a case group of psoriatic patients and a control group of appendectomy patients. Each one had patients from both genders of all age groups. Data were collected by reviewing patients' charts to obtain demographic information, blood pressure, blood glucose level, lipid profile, kidney function, liver function and thyroid function. Results: A total of 140 patients were included (74 males and 66 females). They have been divided into a case group of psoriatic patients and a control group of appendectomy patients, each had 70 participants. The mean age for both groups was 46 ± 18 and 41 ± 15 years, respectively. The proportion of psoriatic patients having diabetes (64%) was found to be higher than the proportion of control patients (46%) (odds ratio [OR], 2.85; 95% confidence interval [CI], 1.12–7.28; P = 0.03). Abnormal renal profile was significantly associated with psoriasis (21%) in comparison to control (3%) (OR, 12.74; 95% CI, 2.28–68.29; P = 0.004). Conclusion: Patients with psoriasis were found to have an increased risk of developing major co-morbid disorders including diabetes, liver and renal function profile abnormalities. This indicates the importance of checking if this group of patients have co-morbid disorders.
背景:银屑病是一种涉及炎症和免疫机制的慢性皮肤病。它会影响身体的外表面,包括皮肤、头发和指甲。它与皮肤外表现和全身性疾病有关。本研究的目的是比较银屑病患者和阑尾切除术患者的慢性疾病,包括糖尿病、高血压、血脂异常、甲状腺功能减退和肾脏和肝脏异常。方法:在利雅得进行病例对照研究。其中包括银屑病患者病例组和阑尾切除术患者对照组。每一个都有来自所有年龄组的男女患者。通过查看患者的图表收集数据,获得人口统计信息、血压、血糖水平、血脂、肾功能、肝功能和甲状腺功能。结果:共纳入140例患者,其中男性74例,女性66例。他们被分为银屑病病例组和阑尾切除术患者对照组,每组70人。两组患者的平均年龄分别为46±18岁和41±15岁。银屑病患者合并糖尿病的比例(64%)高于对照组(46%)(优势比[OR], 2.85;95%置信区间[CI], 1.12-7.28;P = 0.03)。与对照组(3%)相比,肾脏异常与牛皮癣(21%)显著相关(OR, 12.74;95% ci, 2.28-68.29;P = 0.004)。结论:银屑病患者发生糖尿病、肝肾功能异常等主要合并症的风险增加。这表明检查这组患者是否有合并症的重要性。
{"title":"Co-Morbidities in psoriatic versus non-psoriatic patients","authors":"Rana Al Houssien, A. Al sheikh","doi":"10.4103/jhs.JHS_89_17","DOIUrl":"https://doi.org/10.4103/jhs.JHS_89_17","url":null,"abstract":"Background: Psoriasis is a chronic dermatological disorder which involves inflammatory and immune mechanisms. It affects the outer surfaces of the body including skin, hair and nails. It has been related to extracutaneous manifestations and systemic disorders. The aim of this study is to compare the chronic illnesses, including diabetes, hypertension, dyslipidaemia, hypothyroidism and abnormal renal and liver profiles, among patients with psoriasis and patients who had appendectomy. Methods: A case–control study took a place in Riyadh. It included a case group of psoriatic patients and a control group of appendectomy patients. Each one had patients from both genders of all age groups. Data were collected by reviewing patients' charts to obtain demographic information, blood pressure, blood glucose level, lipid profile, kidney function, liver function and thyroid function. Results: A total of 140 patients were included (74 males and 66 females). They have been divided into a case group of psoriatic patients and a control group of appendectomy patients, each had 70 participants. The mean age for both groups was 46 ± 18 and 41 ± 15 years, respectively. The proportion of psoriatic patients having diabetes (64%) was found to be higher than the proportion of control patients (46%) (odds ratio [OR], 2.85; 95% confidence interval [CI], 1.12–7.28; P = 0.03). Abnormal renal profile was significantly associated with psoriasis (21%) in comparison to control (3%) (OR, 12.74; 95% CI, 2.28–68.29; P = 0.004). Conclusion: Patients with psoriasis were found to have an increased risk of developing major co-morbid disorders including diabetes, liver and renal function profile abnormalities. This indicates the importance of checking if this group of patients have co-morbid disorders.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"254 1","pages":"82 - 86"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72761124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Translating the importance of simulation to practice: Strengthening learning outcomes 将模拟的重要性转化为实践:加强学习成果
Pub Date : 2018-04-01 DOI: 10.4103/jhs.JHS_84_17
Farhan F. Alshammari, Eddieson Pasay-an, Maria Charito Laarni Indonto, Ferdinand Gonzales
Background: Evidence against the positive outcomes of simulation exists, but greater evidence for its effectiveness as an educational approach is recorded. Materials and Methods: A quantitative cross-sectional design was employed using a total enumeration from the 2nd year to 4th year nursing students. The respondents were the 2nd to 4th year level Bachelor of Science in Nursing students enrolled during the school year 2016–2017 in the College of Nursing at the University of Hail, Kingdom of Saudi Arabia. Descriptive statistics were used to determine the level of importance and practices of simulation. Meanwhile, the F-test (one-way ANOVA) was used to examine the differences on year level, course, and the age. Results: The level of simulation practice of the students is generally “often practice,” and the importance of simulation is considered “important.” The active learning level of practice is 3.89 while the level of importance is 4.09; collaboration is 3.75 for the level of practice and 3.93 for the level of importance; for the diverse ways of learning 4.13 and 4.14 for the level of importance. Interestingly, as to “high expectations,” the mean result is 4.42 for the level of practices and for the level of importance the mean result is 3.91. According to year level, age and courses, no significant difference in both the level of importance and in the practice of simulation were recorded, as indicated by the P values that were greater than 0.05 level of significance. Conclusion: Specific variables can greatly influence the practice and simulation technique.
背景:反对模拟的积极结果的证据存在,但更多的证据表明其作为一种教育方法的有效性。材料与方法:采用定量横断面设计,对二年级至四年级护生进行总枚举。受访者为2016-2017学年在沙特阿拉伯王国海尔大学护理学院就读的护理学理学士2至4年级学生。使用描述性统计来确定模拟的重要性和实践水平。同时,采用f检验(单因素方差分析)检验年级水平、病程、年龄的差异。结果:学生的模拟实践水平总体为“经常练习”,模拟的重要性为“重要”。实践的主动学习水平为3.89,重要性水平为4.09;协作实践水平为3.75,重要性水平为3.93;对于不同的学习方式4.13和4.14的重要性程度。有趣的是,对于“高期望”,实践水平的平均结果是4.42,重要性水平的平均结果是3.91。按年级、年龄、课程划分,重要性程度和模拟实践程度均无显著差异,P值均大于0.05。结论:具体变量对实践和模拟技术有较大影响。
{"title":"Translating the importance of simulation to practice: Strengthening learning outcomes","authors":"Farhan F. Alshammari, Eddieson Pasay-an, Maria Charito Laarni Indonto, Ferdinand Gonzales","doi":"10.4103/jhs.JHS_84_17","DOIUrl":"https://doi.org/10.4103/jhs.JHS_84_17","url":null,"abstract":"Background: Evidence against the positive outcomes of simulation exists, but greater evidence for its effectiveness as an educational approach is recorded. Materials and Methods: A quantitative cross-sectional design was employed using a total enumeration from the 2nd year to 4th year nursing students. The respondents were the 2nd to 4th year level Bachelor of Science in Nursing students enrolled during the school year 2016–2017 in the College of Nursing at the University of Hail, Kingdom of Saudi Arabia. Descriptive statistics were used to determine the level of importance and practices of simulation. Meanwhile, the F-test (one-way ANOVA) was used to examine the differences on year level, course, and the age. Results: The level of simulation practice of the students is generally “often practice,” and the importance of simulation is considered “important.” The active learning level of practice is 3.89 while the level of importance is 4.09; collaboration is 3.75 for the level of practice and 3.93 for the level of importance; for the diverse ways of learning 4.13 and 4.14 for the level of importance. Interestingly, as to “high expectations,” the mean result is 4.42 for the level of practices and for the level of importance the mean result is 3.91. According to year level, age and courses, no significant difference in both the level of importance and in the practice of simulation were recorded, as indicated by the P values that were greater than 0.05 level of significance. Conclusion: Specific variables can greatly influence the practice and simulation technique.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"77 1","pages":"60 - 67"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88510609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Clinical characteristics and outcomes of acute lymphoblastic leukaemia in children treated at a single tertiary hospital in Riyadh, Saudi Arabia 在沙特阿拉伯利雅得一家三级医院治疗的儿童急性淋巴细胞白血病的临床特征和结局
Pub Date : 2018-01-01 DOI: 10.4103/JHS.JHS_24_17
A. Al Omari, Talal Hussein, K. Albarrak, A. Habib, AlzubeirAnas Sambas, N. Sheblaq, A. Omair
Context: Acute lymphoblastic leukaemia (ALL) is the most common paediatric cancer worldwide, and it accounts for 30% of all cancer cases in children of Saudi Arabia. Aim: This study aims to describe the clinical characteristics and outcomes of paediatric ALL. Settings and Design: This case series study was conducted at a single tertiary hospital in Saudi Arabia. Methods: Clinical data and outcomes of all patients diagnosed between 2000 and 2010 were collected from medical charts using a custom data collection sheet. Statistical Analysis: Data were analysed using SPSS. Mann–Whitney test was used to compare the median age of diagnosis between different categories as the age was not normally distributed. Results: This study included 50 patients (median age, 4 years; 58% male). The majority (82%) had pre-B-cell ALL and 18% had T-cell ALL. Thirty-one (62%) patients were in the standard risk category, 18 (36%) in the high-risk category and one (2%) in the very high-risk category. Forty-nine (98%) patients achieved complete remission. The remission status was M1 marrow status in 46 (94%) patients. The overall survival and event-free survival rates were 92% and 74%, respectively, with 4 (8%) deaths due to different complications. Conclusion: This is the first 10-year case series study in a single tertiary institution in Saudi Arabia. The clinical characteristics of children with ALL were similar to those reported in the literature. The use of well-defined treatment protocols improved the survival rates to levels that are comparable to those of developed countries.
背景:急性淋巴细胞白血病(ALL)是全世界最常见的儿科癌症,占沙特阿拉伯儿童所有癌症病例的30%。目的:本研究旨在描述儿科ALL的临床特征和预后。环境和设计:本病例系列研究在沙特阿拉伯的一家三级医院进行。方法:采用自定义数据收集表,从医学图表中收集2000 - 2010年诊断的所有患者的临床资料和结局。统计分析:采用SPSS软件对数据进行分析。由于年龄非正态分布,采用Mann-Whitney检验比较不同类别患者的中位诊断年龄。结果:本研究纳入50例患者(中位年龄4岁;58%的男性)。大多数(82%)患有b细胞前ALL, 18%患有t细胞ALL。31例(62%)患者属于标准风险类别,18例(36%)属于高危类别,1例(2%)属于高危类别。49例(98%)患者完全缓解。46例(94%)患者缓解状态为M1骨髓状态。总生存率和无事件生存率分别为92%和74%,其中4例(8%)因不同并发症死亡。结论:这是沙特阿拉伯一所高等教育机构的第一个10年病例系列研究。ALL患儿的临床特征与文献报道相似。使用明确的治疗方案将生存率提高到与发达国家相当的水平。
{"title":"Clinical characteristics and outcomes of acute lymphoblastic leukaemia in children treated at a single tertiary hospital in Riyadh, Saudi Arabia","authors":"A. Al Omari, Talal Hussein, K. Albarrak, A. Habib, AlzubeirAnas Sambas, N. Sheblaq, A. Omair","doi":"10.4103/JHS.JHS_24_17","DOIUrl":"https://doi.org/10.4103/JHS.JHS_24_17","url":null,"abstract":"Context: Acute lymphoblastic leukaemia (ALL) is the most common paediatric cancer worldwide, and it accounts for 30% of all cancer cases in children of Saudi Arabia. Aim: This study aims to describe the clinical characteristics and outcomes of paediatric ALL. Settings and Design: This case series study was conducted at a single tertiary hospital in Saudi Arabia. Methods: Clinical data and outcomes of all patients diagnosed between 2000 and 2010 were collected from medical charts using a custom data collection sheet. Statistical Analysis: Data were analysed using SPSS. Mann–Whitney test was used to compare the median age of diagnosis between different categories as the age was not normally distributed. Results: This study included 50 patients (median age, 4 years; 58% male). The majority (82%) had pre-B-cell ALL and 18% had T-cell ALL. Thirty-one (62%) patients were in the standard risk category, 18 (36%) in the high-risk category and one (2%) in the very high-risk category. Forty-nine (98%) patients achieved complete remission. The remission status was M1 marrow status in 46 (94%) patients. The overall survival and event-free survival rates were 92% and 74%, respectively, with 4 (8%) deaths due to different complications. Conclusion: This is the first 10-year case series study in a single tertiary institution in Saudi Arabia. The clinical characteristics of children with ALL were similar to those reported in the literature. The use of well-defined treatment protocols improved the survival rates to levels that are comparable to those of developed countries.","PeriodicalId":31033,"journal":{"name":"Journal of Health Specialties","volume":"344 1","pages":"14 - 18"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76402882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
期刊
Journal of Health Specialties
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1