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Patient-Ventilator Dyssynchrony 过程不同步
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2017.00535
E. Antonogiannaki, D. Georgopoulos, E. Akoumianaki
In mechanically ventilated patients, assisted mechanical ventilation (MV) is employed early, following the acute phase of critical illness, in order to eliminate the detrimental effects of controlled MV, most notably the development of ventilator-induced diaphragmatic dysfunction. Nevertheless, the benefits of assisted MV are often counteracted by the development of patient-ventilator dyssynchrony. Patient-ventilator dyssynchrony occurs when either the initiation and/or termination of mechanical breath is not in time agreement with the initiation and termination of neural inspiration, respectively, or if the magnitude of mechanical assist does not respond to the patient’s respiratory demand. As patient-ventilator dyssynchrony has been associated with several adverse effects and can adversely influence patient outcome, every effort should be made to recognize and correct this occurrence at bedside. To detect patient-ventilator dyssynchronies, the physician should assess patient comfort and carefully inspect the pressure- and flow-time waveforms, available on the ventilator screen of all modern ventilators. Modern ventilators offer several modifiable settings to improve patient-ventilator interaction. New proportional modes of ventilation are also very helpful in improving patient-ventilator interaction.
在机械通气患者中,为了消除受控机械通气的有害影响,尤其是呼吸机引起的膈肌功能障碍,在危重疾病急性期之后的早期采用辅助机械通气(MV)。然而,辅助MV的好处往往被患者-呼吸机不同步的发展所抵消。当机械呼吸的开始和/或终止分别与神经吸气的开始和结束不及时一致,或者机械辅助的大小不能响应患者的呼吸需求时,就会发生患者-呼吸机不同步。由于患者-呼吸机不同步与几种不良反应相关,并可能对患者预后产生不利影响,因此应尽一切努力在床边识别和纠正这种情况。为了检测患者与呼吸机的不同步,医生应评估患者的舒适度,并仔细检查所有现代呼吸机的呼吸机屏幕上提供的压力和流量时间波形。现代呼吸机提供了几个可修改的设置,以改善患者与呼吸机的互动。新的比例通气模式也非常有助于改善患者与呼吸机的互动。
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引用次数: 13
Should Very Old Patients Be Admitted to the Intensive Care Units? 高龄病人应该住进重症监护室吗?
Pub Date : 2017-11-01 Epub Date: 2017-11-30 DOI: 10.4266/kjccm.2017.00521
Jun Kwon Cha, In-Ae Song
I read with great interest the article “Demographic Changes in Intensive Care Units in Korea over the Last Decade and Outcomes of Elderly Patients: A SingleCenter Retrospective Study” published in the Korean Journal of Critical Care Medicine in May 2017 [1]. The results indicated that the proportion of inpatients aged 65–79 years admitted to an intensive care unit (ICU) increased from 47.9% in 2005 to 63.7% in 2014, and the proportion of ICU-hospitalized patients older than 80 years increased from 12.8% in 2005 to 20.7% in 2014. However, the overall mortality rate did not increase despite a higher mortality rate in the elderly than in the younger patients. These results are worthy and impressively demonstrate the recent changing trends in demographic data of ICU patients in Korea. However, I would like to comment on the following two points. First, the authors might have shown a slightly lower sepsis prevalence, not greater than 1% for each subgroup in the ICU. The study conducted by Oh et al. [2], using the Health Insurance Review & Assessment Service database, revealed that the inhospital mortality of patients with sepsis was as high as 38.9%, and the proportion of sepsis increased with age. In addition, in the United States, sepsis was ranked 11 in the top primary diagnoses in 1996 among patients older than 65 years who were admitted to the ICU, but in 2010, sepsis was ranked 1 among the primary diagnoses in older patients admitted to the ICU [3]. In Korea, where the proportion of elderly population is rapidly increasing, it is expected that the rate of primary diagnosis of sepsis in the elderly patients who are admitted to the ICU would be higher. It is considered to be a limitation due to single-center studies, and nationwide demographic studies of ICU patients are required. Second, there had been questions regarding the appropriateness of ICU hospitalization of very old patients (VOPs) aged greater than 80 years with chronic illnesses. Roch et al. [4] reported that among patients older than 80 years, the ICU
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引用次数: 0
Recombinant Activated Factor VII as a Second Line Treatment for Postpartum Hemorrhage 重组活化因子VII作为产后出血的二线治疗
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2016.00787
S. Park, S. Yeom, S. Han, Y. Jo, H. Kim
Background Severe or massive postpartum hemorrhage (PPH) has remained a leading cause of maternal mortality for decades across the world and it results in critical obstetric complications. Recombinant activated factor VII (rFVIIa) has emerged as a gold standard adjunctive hemostatic agent for the treatment of life-threatening PPH refractory to conventional therapies although it remains off-licensed for use in PPH. We studied the effects of rFVIIa on coagulopathy, transfusion volume, prognosis, severity change in Korean PPH patients. Methods A retrospective review of medical records between December 2008 and March 2011 indicating use of rFVIIa in severe PPH was performed. We compared age, rFVIIa treatment, transfusion volume, and Sequential Organ Failure Assessment (SOFA) score at the time of arrival in the emergency department and after 24 hours for patients whose SOFA score was 8 points or higher. Results Fifteen women with SOFA score of 8 and above participated in this study and eight received rFVIIa administration whereas seven did not. Patients’ mean age was 31.7 ± 7.5 years. There was no statistically significant difference in initial and post-24 hours SOFA scores between patients administered rFVIIa or not. The change in SOFA score between initial presentation and after 24 hours was significantly reduced after rFVIIa administration (P = 0.016). Conclusions This analysis aimed to support that the administration of rFVIIa can reduce the severity of life-threatening PPH in patients. A rapid decision regarding the administration of rFVIIa is needed for a more favorable outcome in severe PPH patients for whom there is no effective standard treatment.
几十年来,严重或大量产后出血(PPH)一直是全世界孕产妇死亡的主要原因之一,并可导致严重的产科并发症。重组活化因子VII (rFVIIa)已成为治疗传统疗法难治性危及生命的PPH的金标准辅助止血剂,尽管它在PPH中的使用仍未获得许可。我们研究了rFVIIa对韩国PPH患者凝血功能、输血量、预后、严重程度变化的影响。方法回顾性分析2008年12月至2011年3月间使用rFVIIa治疗重度PPH的病例。我们比较了SOFA评分为8分或更高的患者到达急诊科时和24小时后的年龄、rfvia治疗、输血量和顺序器官衰竭评估(SOFA)评分。结果SOFA评分8分及以上的15名妇女参加了本研究,其中8名接受了rFVIIa治疗,7名未接受rFVIIa治疗。患者平均年龄31.7±7.5岁。给予或未给予rFVIIa的患者的初始和24小时后SOFA评分无统计学差异。在给予rFVIIa后,SOFA评分在首次出现和24小时后的变化显著降低(P = 0.016)。结论本分析旨在支持给予rFVIIa可降低危及生命的PPH患者的严重程度。对于没有有效标准治疗的严重PPH患者,需要迅速决定是否给予rFVIIa,以获得更有利的结果。
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引用次数: 2
Lung Ultrasound in the Critically Ill. 危重病人的肺部超声检查。
Pub Date : 2017-11-01 Epub Date: 2017-11-30 DOI: 10.4266/kjccm.2017.00556
Jin Sun Cho
Until recently, the lung was considered “forbidden territory” for ultrasound. With lung ultrasound, however, the amount of lung consolidation and pleural effusion can be assessed semiquantitatively. Lung ultrasound consists of the identification of 10 signs, and there are several well-established protocols such as the BLUE (Bedside Lung Ultrasonography in Emergency) protocol for diagnosing acute respiratory failure and the FALLS (Fluid Administration Limited by Lung Sonography) protocol for managing acute circulatory failure. The BLUE protocol is a fast protocol that defines eight profiles, correlated with six diseases seen in 97% of patients admitted to the intensive care unit (ICU). With this protocol, it becomes possible to differentiate between pulmonary edema, pulmonary embolism, pneumonia, chronic obstructive pulmonary disease, asthma, and pneumothorax [1]. The FALLS protocol uses the potential of lung ultrasound for the early demonstration of fluid overload at an infra-clinical level [2]. It is used in patients with acute respiratory failure, allowing a sequential search for obstructive, cardiogenic, hypovolemic, and distributive shock using simple real-time echocardiography in combination with lung ultrasound, with the appearance of B lines considered to be the endpoint of fluid therapy. In addition, ultrasound can help to guide airway management in a patient with acute respiratory distress who needs to be intubated and mechanically ventilated (PINK protocol). In a patient with acute respiratory distress who is often ventilated and difficult to transport, computed tomography (CT) is not an easy option, and lung ultrasound can help to predict difficult airway and proper endotracheal tube size, or to confirm proper endotracheal tube placement with avoidance of desaturation during CT [3]. In addition, lung ultrasound can be used to determine the cause of fever distinguishing pneumonia from atelectasis [4], and to rule out pneumothorax, hypovolemia, pulmonary embolism and pericardial tamponade in cardiac arrest (SESAME protocol) [5]. In the critical care setting, lung ultrasound is increasingly used, as it allows bedside visualization of the lungs. Critical care ultrasound is a combination of simple protocols, with lung ultrasound being a basic application, allowing the assessment
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引用次数: 7
Serum Albumin as a Biomarker of Poor Prognosis in the Pediatric Patients in Intensive Care Unit 血清白蛋白作为重症监护病房儿科患者预后不良的生物标志物
Pub Date : 2017-11-01 DOI: 10.4266/KJCCM.2017.00437
Young Suh Kim, I. Sol, Min Jung Kim, Soo-Yeon Kim, Jong Deok Kim, Y. Kim, K. Kim, M. Sohn, Kyu-Earn Kim
Background Serum albumin as an indicator of the disease severity and mortality is suggested in adult patients, but its role in pediatric patients has not been established. The objectives of this study are to investigate the albumin level as a biomarker of poor prognosis and to compare it with other mortality predictive indices in children in intensive care unit (ICU). Methods Medical records of 431 children admitted to the ICU at Severance Hospital from January 1, 2012 to December 31, 2015 were retrospectively analyzed. Children who expired within 24 hours after ICU admission, children with hepatic or renal failure, and those who received albumin replacement before ICU admission were excluded. Results The children with hypoalbuminemia had higher 28-day mortality rate (24.60% vs. 9.28%, P < 0.001), Pediatric Index of Mortality (PIM) 3 score (9.23 vs. 8.36, P < 0.001), Pediatric Risk of Mortality (PRISM) III score (7.0 vs. 5.0, P < 0.001), incidence of septic shock (12% vs. 3%, P < 0.001), C-reactive protein (33.0 mg/L vs. 5.8 mg/L, P < 0.001), delta neutrophil index (2.0% vs. 0.6%, P < 0.001), lactate level (1.6 mmol/L vs. 1.2 mmol/L, P < 0.001) and lower platelet level (206,000/μl vs. 341,000/μl, P < 0.001) compared to the children with normal albumin level. PIM 3 (r = 0.219, P < 0.001) and PRISM III (r = 0.375, P < 0.001) were negatively correlated with serum albumin level, respectively. Conclusions Our results highlight that hypoalbuminemia can be a biomarker of poor prognosis including mortality in the children in ICU.
背景血清白蛋白作为疾病严重程度和死亡率的指标被建议用于成人患者,但其在儿科患者中的作用尚未确定。本研究的目的是研究白蛋白水平作为不良预后的生物标志物,并将其与重症监护室(ICU)儿童的其他死亡率预测指标进行比较。方法回顾性分析2012年1月1日至2015年12月31日在Severance医院ICU住院的431名儿童的病历。ICU入院后24小时内过期的儿童、肝或肾功能衰竭的儿童以及在ICU入院前接受白蛋白置换的儿童均被排除在外。结果低白蛋白血症患儿28天死亡率(24.60%对9.28%,P<0.001)、儿童死亡率指数(PIM)3分(9.23对8.36,P<0.01)、儿童死亡风险(PRISM)III分(7.0对5.0,P<001)、感染性休克发生率(12%对3%,P<0.05)、C反应蛋白(33.0 mg/L对5.8 mg/L,P<0.005)、,与白蛋白水平正常的儿童相比,中性粒细胞指数(2.0%对0.6%,P<0.001)、乳酸水平(1.6 mmol/L对1.2 mmol/L,P<0.01)和血小板水平较低(206000/μL对341000/μL,P<001)。PIM 3(r=0.219,P<0.001)和PRISM III(r=0.375,P<0.01)分别与血清白蛋白水平呈负相关。结论我们的研究结果强调,低白蛋白血症可能是ICU儿童预后不良(包括死亡率)的生物标志物。
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引用次数: 10
The Authors Reply 作者的回答
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2017.00521.r1
Jeong Uk Lim, Jongmin Lee, J. Ha, H. Kang, S. H. Lee, H. Moon
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引用次数: 0
A Pleural Catheter Malposition through Diaphragm to Abdominal Cavity 经膈入腹腔的胸膜导管错位
Pub Date : 2017-11-01 DOI: 10.4266/KJCCM.2017.00290
W. Jung, Sue In Choi, E. Lee, Sang Yeub Lee, K. In
A 78-old-man with history of diabetes mellitus and cerebral infarction was transferred to intensive care unit of Korea University Anam Hospital from nursing hospital. He presented with acute respiratory failure requiring mechanical ventilation caused by pneumonia and empyema. We inserted chest tube for empyema on the right side. A few days later, pleural effusion occurred on the left side. Thus, pleural catheter was inserted into left seventh intercostal space at the mid axillary line after marking of site using ultrasound. Chest simple radiography showed that the catheter direction had been inserted too downward (Figure 1A). A subsequent computed tomography scan revealed that the catheter first entered into the pleural space, passed through diaphragm, and the tip was located in the abdominal cavity (Figure 1B). The catheter was removed immediately with a close monitoring. After catheter removal, the patient was still stable and showed no signs or symptoms of any complication. The rate of chest tube malposition is less than 3% and 0.6% especially for small drain [1,2]. Pleural catheter malposition was very rarely reported [3]. Pleural catheter into the abdominal cavity through diaphragm is an exceptional complication. Various complications from chest tube misplacement into the abdominal cavity
一位有糖尿病和脑梗死病史的78岁老人从护理医院转入韩国大学安医院重症监护室。他出现了由肺炎和脓胸引起的需要机械通气的急性呼吸衰竭。我们在右侧插入胸管治疗脓胸。几天后,左侧出现胸腔积液。因此,在使用超声标记部位后,将胸膜导管插入腋窝中线的左侧第七肋间。胸部简单射线照相显示导管方向向下插入过多(图1A)。随后的计算机断层扫描显示,导管首先进入胸膜腔,穿过横膈膜,尖端位于腹腔内(图1B)。在密切监测下立即取出导管。移除导管后,患者仍然稳定,没有任何并发症的迹象或症状。胸管错位的发生率分别低于3%和0.6%,尤其是小引流管[1,2]。胸膜导管错位的报道很少[3]。胸膜导管通过横膈膜进入腹腔是一种特殊的并发症。胸管置入腹腔的各种并发症
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引用次数: 1
Acute Physiology and Chronic Health Evaluation II Score and Sequential Organ Failure Assessment Score as Predictors for Severe Trauma Patients in the Intensive Care Unit 急性生理学和慢性健康评估II评分和序贯器官衰竭评估评分作为重症监护室严重创伤患者的预测指标
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2017.00255
Min A Lee, K. Choi, B. Yu, Jae Jeong Park, Youngeun Park, Jihun Gwak, Jungnam Lee, Y. Jeon, D. Ma, G. Lee
Background The Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system and the Sequential Organ Failure Assessment (SOFA) scoring system are widely used for critically ill patients. We evaluated whether APACHE II score and SOFA score predict the outcome for trauma patients in the intensive care unit (ICU). Methods We retrospectively analyzed trauma patients admitted to the ICU in a single trauma center between January 2014 and December 2015. The APACHE II score was figured out based on the data acquired from the first 24 hours of admission; the SOFA score was evaluated based on the first 3 days in the ICU. A total of 241 patients were available for analysis. Injury Severity score, APACHE II score, and SOFA score were evaluated. Results The overall survival rate was 83.4%. The non-survival group had a significantly high APACHE II score (24.1 ± 8.1 vs. 12.3 ± 7.2, P < 0.001) and SOFA score (7.7 ± 1.7 vs. 4.3 ± 1.9, P < 0.001) at admission. SOFA score had the highest areas under the curve (0.904). During the first 3 days, SOFA score remained high in the non-survival group. In the non-survival group, cardiovascular system, neurological system, renal system, and coagulation system scores were significantly higher. Conclusions In ICU trauma patients, both SOFA and APACHE II scores were good predictors of outcome, with the SOFA score being the most effective. In trauma ICU patients, the trauma scoring system should be complemented, recognizing that multi-organ failure is an important factor for mortality.
背景急性生理与慢性健康评估(APACHE) II评分系统和序期器官衰竭评估(SOFA)评分系统被广泛应用于危重患者。我们评估了APACHE II评分和SOFA评分是否能预测重症监护病房(ICU)创伤患者的预后。方法回顾性分析2014年1月至2015年12月在某外伤中心ICU收治的外伤患者。根据入院前24小时的数据计算APACHE II评分;SOFA评分基于患者在ICU的前3天进行评估。共有241例患者可用于分析。评估损伤严重程度评分、APACHE II评分和SOFA评分。结果总生存率为83.4%。非生存组入院时APACHEⅱ评分(24.1±8.1比12.3±7.2,P < 0.001)和SOFA评分(7.7±1.7比4.3±1.9,P < 0.001)均显著较高。SOFA评分曲线下面积最大(0.904)。在前3天,非生存组的SOFA评分仍然很高。在非生存组中,心血管系统、神经系统、肾脏系统和凝血系统评分明显较高。结论在ICU创伤患者中,SOFA和APACHE II评分均能很好地预测预后,其中SOFA评分最有效。在创伤ICU患者中,应补充创伤评分系统,认识到多器官功能衰竭是死亡率的重要因素。
{"title":"Acute Physiology and Chronic Health Evaluation II Score and Sequential Organ Failure Assessment Score as Predictors for Severe Trauma Patients in the Intensive Care Unit","authors":"Min A Lee, K. Choi, B. Yu, Jae Jeong Park, Youngeun Park, Jihun Gwak, Jungnam Lee, Y. Jeon, D. Ma, G. Lee","doi":"10.4266/kjccm.2017.00255","DOIUrl":"https://doi.org/10.4266/kjccm.2017.00255","url":null,"abstract":"Background The Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system and the Sequential Organ Failure Assessment (SOFA) scoring system are widely used for critically ill patients. We evaluated whether APACHE II score and SOFA score predict the outcome for trauma patients in the intensive care unit (ICU). Methods We retrospectively analyzed trauma patients admitted to the ICU in a single trauma center between January 2014 and December 2015. The APACHE II score was figured out based on the data acquired from the first 24 hours of admission; the SOFA score was evaluated based on the first 3 days in the ICU. A total of 241 patients were available for analysis. Injury Severity score, APACHE II score, and SOFA score were evaluated. Results The overall survival rate was 83.4%. The non-survival group had a significantly high APACHE II score (24.1 ± 8.1 vs. 12.3 ± 7.2, P < 0.001) and SOFA score (7.7 ± 1.7 vs. 4.3 ± 1.9, P < 0.001) at admission. SOFA score had the highest areas under the curve (0.904). During the first 3 days, SOFA score remained high in the non-survival group. In the non-survival group, cardiovascular system, neurological system, renal system, and coagulation system scores were significantly higher. Conclusions In ICU trauma patients, both SOFA and APACHE II scores were good predictors of outcome, with the SOFA score being the most effective. In trauma ICU patients, the trauma scoring system should be complemented, recognizing that multi-organ failure is an important factor for mortality.","PeriodicalId":31220,"journal":{"name":"Korean Journal of Critical Care Medicine","volume":"32 1","pages":"340 - 346"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47175979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The Use of Lung Ultrasound in a Surgical Intensive Care Unit 肺部超声在外科重症监护室的应用
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2017.00318
Hyung Koo Kang, Hyojyo So, Deok Hee Kim, H. Koo, Hye Kyeong Park, Sung-Soon Lee, Hoon Jung
Background Pulmonary complications including pneumonia and pulmonary edema frequently develop in critically ill surgical patients. Lung ultrasound (LUS) is increasingly used as a powerful diagnostic tool for pulmonary complications. The purpose of this study was to report how LUS is used in a surgical intensive care unit (ICU). Methods This study retrospectively reviewed the medical records of 67 patients who underwent LUS in surgical ICU between May 2016 and December 2016. Results The indication for LUS included hypoxemia (n = 44, 65.7%), abnormal chest radiographs without hypoxemia (n = 17, 25.4%), fever without both hypoxemia and abnormal chest radiographs (n = 4, 6.0%), and difficult weaning (n = 2, 3.0%). Among 67 patients, 55 patients were diagnosed with pulmonary edema (n = 27, 41.8%), pneumonia (n = 20, 29.9%), diffuse interstitial pattern with anterior consolidation (n = 6, 10.9%), pneumothorax with effusion (n = 1, 1.5%), and diaphragm dysfunction (n = 1, 1.5%), respectively, via LUS. LUS results did not indicate lung complications for 12 patients. Based on the location of space opacification on the chest radiographs, among 45 patients with bilateral abnormality and normal findings, three (6.7%) and two (4.4%) patients were finally diagnosed with pneumonia and atelectasis, respectively. Furthermore, among 34 patients with unilateral abnormality and normal findings, two patients (5.9%) were finally diagnosed with pulmonary edema. There were 27 patients who were initially diagnosed with pulmonary edema via LUS. This diagnosis was later confirmed by other tests. There were 20 patients who were initially diagnosed with pneumonia via LUS. Among them, 16 and 4 patients were finally diagnosed with pneumonia and atelectasis, respectively. Conclusions LUS is useful to detect pulmonary complications including pulmonary edema and pneumonia in surgically ill patients.
背景危重外科患者经常发生肺部并发症,包括肺炎和肺水肿。肺部超声(LUS)越来越多地被用作肺部并发症的强大诊断工具。本研究的目的是报告LUS如何在外科重症监护室(ICU)中使用。方法回顾性分析2016年5月至2016年12月在外科ICU接受LUS治疗的67例患者的病历。结果LUS的指征包括低氧血症(n=44,65.7%)、无低氧血症的异常胸部X线片(n=17,25.4%)、既没有低氧血症又没有异常胸部x线片的发烧(n=4,6.0%)和断奶困难(n=2,3.0%),经LUS检查,弥漫性间质型伴前部实变(n=6,09%)、伴有积液的肺气肿(n=1,1.5%)和膈肌功能障碍(n=1/1.5%)。LUS结果未显示12例患者的肺部并发症。根据胸部X线片上间隙混浊的位置,在45例双侧异常和正常的患者中,分别有3例(6.7%)和2例(4.4%)最终被诊断为肺炎和肺不张。此外,在34名单侧异常和正常表现的患者中,有两名患者(5.9%)最终被诊断为肺水肿。有27名患者最初通过LUS诊断为肺水肿。这一诊断后来通过其他测试得到了证实。有20名患者最初通过LUS被诊断为肺炎。其中,分别有16名和4名患者最终被诊断为肺炎和肺不张。结论LUS可用于检测外科病人的肺部并发症,包括肺水肿和肺炎。
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引用次数: 2
Spontaneous Echo Contrast Mistaken for Left Ventricular Thrombus during Venoarterial Extracorporeal Membrane Oxygenation 体外膜肺氧合期间左室血栓的自发回声对比错误
Pub Date : 2017-11-01 DOI: 10.4266/kjccm.2017.00220
S. Lee, So Young Lee, C. Choi, K. Park, C. Park
Spontaneous echo contrast (SEC) is often observed in patients with mitral stenosis, atrial fibrillation, cardiomyopathy, or a ventricular aneurysm [1]. SEC is a smoke-like echo density observed on echocardiograms, and is caused by increased red blood cell aggregation during low-flow states. It is also a risk factor of thromboembolism [2]. SEC can be observed in patients with severe ventricular dysfunction receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). We present a case in which left ventricular-SEC (LV-SEC) was mistaken for a LV thrombus during VA-ECMO for severe LV dysfunction. A 36-year-old female patient diagnosed with acute fulminant myocarditis was provided VA-ECMO support on hospital day (HD) 1. Briefly, VA-ECMO (RotaFlow; Maquet Inc., Hirrlingen, Germany) was implanted in the right femoral artery (15-French arterial cannula) and the left femoral vein (20-French venous cannula). Her height and body weight are 163 cm and 52 kg (body surface area, 1.53 m). VAECMO was initiated with a circuit flow of 3.5 L/min (cardiac index, 2.3 2L/min/m). Her creatine kinase-myocardial band and troponin-I levels at admission were 188.03 ng/ml (normal range, 0 to 5 ng/ml) and >50.0 ng/ml (normal range, 0 to 0.78 ng/ml), respectively. Impaired ventricular function (ejection fraction, 22%) suspected as acute fulminant myocarditis was detected by transthoracic echocardiography (TTE) at admission. TTE revealed decreased LV function (ejection fraction, 10%) with mild mitral regurgitation (grade II) immediately after VA-ECMO. Opening of the aortic valve and arterial pulsatility were not observed. Pulmonary edema was aggravated on HD 4. Left atrial (LA) decompression was achieved using a LA catheter (20-French femoral venous cannula) by balloon atrial septostomy through the right femoral
在二尖瓣狭窄、心房颤动、心肌病或室壁瘤患者中经常观察到自发回声对比(SEC)[1]。SEC是超声心动图上观察到的烟雾状回声密度,是由低流量状态下红细胞聚集增加引起的。它也是血栓栓塞的一个危险因素[2]。在接受静脉-动脉体外膜肺氧合(VA-ECMO)治疗的严重心室功能障碍患者中可以观察到SEC。我们提出了一个病例,其中左心室SEC(LV-SEC)在VA-ECMO期间被误认为是严重左心室功能障碍的左心室血栓。一名被诊断为急性暴发性心肌炎的36岁女性患者在住院日(HD)1接受了VA-ECMO支持。简言之,将VA-ECMO(RotaFlow;Maquet股份有限公司,Hirrlingen,Germany)植入右股动脉(15-French动脉插管)和左股静脉(20-French静脉插管)中。她的身高和体重分别为163厘米和52公斤(体表面积1.53米)。VAECMO以3.5L/min的循环流量(心脏指数,2.32L/min/m)启动。入院时,她的肌酸激酶心肌带和肌钙蛋白I水平分别为188.03 ng/ml(正常范围,0-5 ng/ml)和>5.0 ng/ml(异常范围,0-0.78 ng/ml)。入院时经胸超声心动图(TTE)检测到疑似急性暴发性心肌炎的心室功能受损(射血分数,22%)。经胸超声心动图显示VA-ECMO术后左心室功能下降(射血分数10%),伴有轻度二尖瓣反流(II级)。未观察到主动脉瓣开放和动脉搏动。HD 4时肺水肿加重。左心房(LA)减压采用左心房导管(20法国股静脉套管),通过右股球囊心房间隔造口术实现
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引用次数: 0
期刊
Korean Journal of Critical Care Medicine
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