Pub Date : 2020-03-24DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.14777
Andreia Lomba, A. Ferraz, Sónia Regina Silva, M. Flores, A. Saraiva
Children are more susceptible than adults to development of tuberculosis after exposure to active disease, hence screening and chemoprophylaxis are particularly important. Although Portugal is considered to have a low burden of tuberculosis, educating the population on the importance of screening and treatment is vital to decrease the number of cases. Herein is reported the case of an 11-year-old girl with previous contact with active tuberculosis who was lost to follow-up and later diagnosed with bacillary pulmonary tuberculosis.
{"title":"Pediatric bacillary pulmonary tuberculosis - case report","authors":"Andreia Lomba, A. Ferraz, Sónia Regina Silva, M. Flores, A. Saraiva","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.14777","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.14777","url":null,"abstract":"Children are more susceptible than adults to development of tuberculosis after exposure to active disease, hence screening and chemoprophylaxis are particularly important. Although Portugal is considered to have a low burden of tuberculosis, educating the population on the importance of screening and treatment is vital to decrease the number of cases. Herein is reported the case of an 11-year-old girl with previous contact with active tuberculosis who was lost to follow-up and later diagnosed with bacillary pulmonary tuberculosis.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"49 1","pages":"56-58"},"PeriodicalIF":0.0,"publicationDate":"2020-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83397125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-24DOI: 10.25753/BIRTHGROWTHMJ.V28.I2.15709
C. Liz, Joaquim Cunha, S. Lira
Introduction: Insulin edema is a rare condition associated with improved glycemic control shortly after diabetes diagnosis or following a period of insulin omission. Clinical findings range from mild edema to severe heart failure and pleural effusion. Diagnosis is clinical and other edema causes should be excluded. Since it is a self-limited condition, there is no need to modify insulin regimen. In more severe cases, diuretic therapy may be required.Clinical case: A 14-year-old female was brought to the Emergency Department due to weight gain and leg swelling with three days of evolution. She had been diagnosed with type 1 diabetes at the age of nine. The girl had poor metabolic control which led to multiple hospitalizations, the last one occurring the week before with a glycated hemoglobin higher than 15%. In physical examination, lower limb edema and a 7-kg weight gain were noted. No jugular vein distension, hepatomegaly, or other forms of edema were found. The girl was hemodynamically stable, with diuresis within the normal range. Analytical study consisting of hemogram, ionogram (sodium and potassium), and renal and hepatic function was normal. Urine analysis revealed glycosuria and chest x-ray showed no abnormalities. The diagnosis of insulin-induced edema was established and water and saline restriction recommended, with total symptom resolution three weeks later.Conclusion: Despite rare, clinicians should be aware of this condition, as most cases do not require modifying the insulin regimen.
{"title":"Insulin-induced edema in a pediatric patient - clinical case","authors":"C. Liz, Joaquim Cunha, S. Lira","doi":"10.25753/BIRTHGROWTHMJ.V28.I2.15709","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V28.I2.15709","url":null,"abstract":"Introduction: Insulin edema is a rare condition associated with improved glycemic control shortly after diabetes diagnosis or following a period of insulin omission. Clinical findings range from mild edema to severe heart failure and pleural effusion. Diagnosis is clinical and other edema causes should be excluded. Since it is a self-limited condition, there is no need to modify insulin regimen. In more severe cases, diuretic therapy may be required.Clinical case: A 14-year-old female was brought to the Emergency Department due to weight gain and leg swelling with three days of evolution. She had been diagnosed with type 1 diabetes at the age of nine. The girl had poor metabolic control which led to multiple hospitalizations, the last one occurring the week before with a glycated hemoglobin higher than 15%. In physical examination, lower limb edema and a 7-kg weight gain were noted. No jugular vein distension, hepatomegaly, or other forms of edema were found. The girl was hemodynamically stable, with diuresis within the normal range. Analytical study consisting of hemogram, ionogram (sodium and potassium), and renal and hepatic function was normal. Urine analysis revealed glycosuria and chest x-ray showed no abnormalities. The diagnosis of insulin-induced edema was established and water and saline restriction recommended, with total symptom resolution three weeks later.Conclusion: Despite rare, clinicians should be aware of this condition, as most cases do not require modifying the insulin regimen.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"89 1","pages":"43-46"},"PeriodicalIF":0.0,"publicationDate":"2020-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80369401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-24DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.15101
A. Frascino, L. Cominato
Small-for-gestational-age children have been associated with up to 20% delayed growth and delayed development, increased childhood morbimortality, and poor quality of life. Prepubertal growth hormone administration results in increased growth and musculoskeletal development. The present case report illustrates the negative impact of growth hormone disruption in a 6-year-old patient, resulting in impaired growth and development. Close clinical and laboratory monitoring is recommended for small-for-gestational-age children receiving growth hormone treatment, and family counselling should be encouraged.
{"title":"Treatment interruption in small for age term-born children","authors":"A. Frascino, L. Cominato","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.15101","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.15101","url":null,"abstract":"Small-for-gestational-age children have been associated with up to 20% delayed growth and delayed development, increased childhood morbimortality, and poor quality of life. Prepubertal growth hormone administration results in increased growth and musculoskeletal development. The present case report illustrates the negative impact of growth hormone disruption in a 6-year-old patient, resulting in impaired growth and development. Close clinical and laboratory monitoring is recommended for small-for-gestational-age children receiving growth hormone treatment, and family counselling should be encouraged.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"15 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2020-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74482916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-24DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.16074
Raquel Oliveira, D. Bordalo, S. Carvalho, Paula Fonseca
A previously healthy 15-year-old girl was sent to the Pediatric Emergency Department by the general practitioner due to suspicion of a hematological condition. The girl presented with ecchymotic lesions on the anterior region of the thorax and antero-proximal region of the upper limbs, which had apparently worsened in the last 24 hours. She denied trauma or impact sports, fever or recent infections, and blood loss or other symptoms. Laboratory evaluation showed no alterations and urine toxicology screening was negative. When confronted with normal laboratory evaluation, the girl confessed intentional self-inflicted injuries following a discussion with her mother. Parents were made aware of the situation, and a pediatric psychiatry consultation was recommended. After discharge, follow-up in the girl’s home country was assured.With this report, the author intend to raise awareness of the importance of maintaining a high index of suspicion to non-suicidal self-injury, identifying alarm signs and establishing early preventive strategies.
{"title":"Dermatology clinical case","authors":"Raquel Oliveira, D. Bordalo, S. Carvalho, Paula Fonseca","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.16074","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.16074","url":null,"abstract":"A previously healthy 15-year-old girl was sent to the Pediatric Emergency Department by the general practitioner due to suspicion of a hematological condition. The girl presented with ecchymotic lesions on the anterior region of the thorax and antero-proximal region of the upper limbs, which had apparently worsened in the last 24 hours. She denied trauma or impact sports, fever or recent infections, and blood loss or other symptoms. Laboratory evaluation showed no alterations and urine toxicology screening was negative. When confronted with normal laboratory evaluation, the girl confessed intentional self-inflicted injuries following a discussion with her mother. Parents were made aware of the situation, and a pediatric psychiatry consultation was recommended. After discharge, follow-up in the girl’s home country was assured.With this report, the author intend to raise awareness of the importance of maintaining a high index of suspicion to non-suicidal self-injury, identifying alarm signs and establishing early preventive strategies.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"96 3 1","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2020-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77715300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-15DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.18081
Teresa Sá, F. Silva, P. Magalhães, Vânia Martins, Paula Barrias
{"title":"Sintomas psicóticos durante o tratamento com psicoestimulantes para a perturbação de hiperatividade com défice de atenção","authors":"Teresa Sá, F. Silva, P. Magalhães, Vânia Martins, Paula Barrias","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.18081","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.18081","url":null,"abstract":"","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"29 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41997264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-15DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.17978
Joana Peixoto, C. França, S. Barge, M. Branco
Introduction: Sucking reflex is acknowledged as a comforting mechanism for infants. When used for short periods of time, it is considered a healthy habit. Acute otitis media is one of the most frequent infections in pediatric age and has been associated with pacifier misuse.Objectives: To review available evidence regarding the association between pacifier use in the first years of life and otitis media risk. Methods: A literature search was conducted on several databases using MeSH terms “otitis” and “pacifiers” for guidelines, systematic reviews, randomized controlled trials, and observational studies over the last 20 years. SORT scale of the American Family Physician was used to evaluate evidence levels.Results: A total of 56 articles were retrieved, of which four guidelines, one systematic review, and one original article were selected. According to guidelines, there is no reason to discourage pacifier use, as it can be particularly beneficial in the first six months of life. Afterwards, pacifier use should be limited to moments of falling asleep. Its use should also be avoided in infants with chronic or recurrent otitis media. The systematic review stablished pacifier use as a risk factor for recurrent acute otitis media (RAOM) which is susceptible to intervention. In the observational study, a statistically significant association was found between pacifier use and RAOM risk.Conclusions: Pacifier use should not be actively discouraged in the first semester of life, as it can have beneficial effects for children (SORT A). Afterwards, its use should be discontinued due to increased otitis risk (SORT A).
{"title":"What role for the pacifier in acute otitis media risk","authors":"Joana Peixoto, C. França, S. Barge, M. Branco","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.17978","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.17978","url":null,"abstract":"Introduction: Sucking reflex is acknowledged as a comforting mechanism for infants. When used for short periods of time, it is considered a healthy habit. Acute otitis media is one of the most frequent infections in pediatric age and has been associated with pacifier misuse.Objectives: To review available evidence regarding the association between pacifier use in the first years of life and otitis media risk. Methods: A literature search was conducted on several databases using MeSH terms “otitis” and “pacifiers” for guidelines, systematic reviews, randomized controlled trials, and observational studies over the last 20 years. SORT scale of the American Family Physician was used to evaluate evidence levels.Results: A total of 56 articles were retrieved, of which four guidelines, one systematic review, and one original article were selected. According to guidelines, there is no reason to discourage pacifier use, as it can be particularly beneficial in the first six months of life. Afterwards, pacifier use should be limited to moments of falling asleep. Its use should also be avoided in infants with chronic or recurrent otitis media. The systematic review stablished pacifier use as a risk factor for recurrent acute otitis media (RAOM) which is susceptible to intervention. In the observational study, a statistically significant association was found between pacifier use and RAOM risk.Conclusions: Pacifier use should not be actively discouraged in the first semester of life, as it can have beneficial effects for children (SORT A). Afterwards, its use should be discontinued due to increased otitis risk (SORT A).","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"24 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73833686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-15DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.17587
A. Sequeira, D. Rocha, C. Dias, L. Carreira, E. Cleto
{"title":"Immune neonatal thrombocytopenia - review","authors":"A. Sequeira, D. Rocha, C. Dias, L. Carreira, E. Cleto","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.17587","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.17587","url":null,"abstract":"","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"23 1","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82465364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-15DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.19728
Natália Oliva-Teles
{"title":"Disease modelling and drug development with iPSC-derived cells: a brave new world?","authors":"Natália Oliva-Teles","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.19728","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.19728","url":null,"abstract":"","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"36 1","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86730077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-15DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.15081
R. Martins, Lia Raquel Moreira Oliveira, R. Ferreira
Introducao/Objetivo: A insonia comportamental e um disturbio do sono frequente em idade pediatrica, com repercussoes potencialmente negativas na saude, comportamento e capacidade cognitiva das criancas. O objetivo deste estudo foi caracterizar a populacao referenciada a uma consulta pediatrica do sono de um hospital terciario por insonia comportamental. Metodos: Estudo retrospetivo e descritivo baseado na revisao de processos clinicos de doentes seguidos por insonia na referida consulta especializada durante um periodo de oito anos (2008−2016). Os resultados sao apresentados como mediana (minimo–maximo), media (desvio padrao) e percentagem. Resultados: No total, 964 criancas foram referenciadas a consulta de sono, 162 (16.8%) das quais por insonia e 137 (14.2%) por insonia comportamental. A maioria (58.4%) era do sexo masculino e a mediana de idades aquando da referenciacao foi de 45 meses (5 meses–18 anos). A mediana da hora de deitar foi 22:00 (20:00–4:00), tendo sido frequentes os despertares noturnos, sobretudo em idade pre-escolar. Relativamente as rotinas na hora de deitar, 62% das criancas nao adormeciam sozinhas, 48.9% tinham televisao no quarto e 43.1% (11.9% das quais, adolescentes) precisavam de um objeto e 42.3% de luz acesa para adormecer. A maioria (62%) das criancas tinha uma rotina para adormecer, dependente do cuidador em criancas mais novas e de televisao e leitura nos adolescentes. Os sintomas diarios mais frequentemente referidos foram sonolencia em criancas mais velhas e irritabilidade em criancas mais novas. Relativamente ao tratamento, 29.9% encontrava-se a receber tratamento farmacologico antes da referenciacao. Conclusao: A maioria das criancas neste estudo encontrava-se em idade pre-escolar, a qual constitui uma importante janela de atuacao. A hora de deitar tardia, presenca de televisao no quarto e dependencia dos pais para adormecer foram frequentes, o que revela a necessidade de intervencao na area. Os autores propoem um maior investimento na formacao dos profissionais de saude e cuidadores, de modo a promover a adocao de medidas de higiene do sono adequadas como forma de prevencao.
{"title":"Behavioral insomnia in a pediatric sleep clinic: retrospective study","authors":"R. Martins, Lia Raquel Moreira Oliveira, R. Ferreira","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.15081","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.15081","url":null,"abstract":"Introducao/Objetivo: A insonia comportamental e um disturbio do sono frequente em idade pediatrica, com repercussoes potencialmente negativas na saude, comportamento e capacidade cognitiva das criancas. O objetivo deste estudo foi caracterizar a populacao referenciada a uma consulta pediatrica do sono de um hospital terciario por insonia comportamental. Metodos: Estudo retrospetivo e descritivo baseado na revisao de processos clinicos de doentes seguidos por insonia na referida consulta especializada durante um periodo de oito anos (2008−2016). Os resultados sao apresentados como mediana (minimo–maximo), media (desvio padrao) e percentagem. Resultados: No total, 964 criancas foram referenciadas a consulta de sono, 162 (16.8%) das quais por insonia e 137 (14.2%) por insonia comportamental. A maioria (58.4%) era do sexo masculino e a mediana de idades aquando da referenciacao foi de 45 meses (5 meses–18 anos). A mediana da hora de deitar foi 22:00 (20:00–4:00), tendo sido frequentes os despertares noturnos, sobretudo em idade pre-escolar. Relativamente as rotinas na hora de deitar, 62% das criancas nao adormeciam sozinhas, 48.9% tinham televisao no quarto e 43.1% (11.9% das quais, adolescentes) precisavam de um objeto e 42.3% de luz acesa para adormecer. A maioria (62%) das criancas tinha uma rotina para adormecer, dependente do cuidador em criancas mais novas e de televisao e leitura nos adolescentes. Os sintomas diarios mais frequentemente referidos foram sonolencia em criancas mais velhas e irritabilidade em criancas mais novas. Relativamente ao tratamento, 29.9% encontrava-se a receber tratamento farmacologico antes da referenciacao. Conclusao: A maioria das criancas neste estudo encontrava-se em idade pre-escolar, a qual constitui uma importante janela de atuacao. A hora de deitar tardia, presenca de televisao no quarto e dependencia dos pais para adormecer foram frequentes, o que revela a necessidade de intervencao na area. Os autores propoem um maior investimento na formacao dos profissionais de saude e cuidadores, de modo a promover a adocao de medidas de higiene do sono adequadas como forma de prevencao.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"3 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91357223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.25753/BIRTHGROWTHMJ.V29.I1.14036
J. Félix, J. M. Barros, Ana Soares, Fátima Soares, Rosete Nogueira, Pedro Tiago Silva
{"title":"A importância da ecografia no diagnóstico pré-natal da associação vacterl - dois casos clínicos","authors":"J. Félix, J. M. Barros, Ana Soares, Fátima Soares, Rosete Nogueira, Pedro Tiago Silva","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.14036","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.14036","url":null,"abstract":"","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"29 1","pages":"51-55"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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