Pub Date : 2025-05-01DOI: 10.1016/j.rx.2024.01.010
M. Arraiza , E. Chacón , A. Ezponda , D. Cano , J.Á. Mínguez , A. Benito , J.L. Alcázar
Introduction
Despite the overall high accuracy of the O-RADS MRI scoring system for characterization of indeterminate adnexal lesions, a non-negligible percentage of adnexal lesions remains indeterminate. Given this, the main objective of this study was to evaluate the value of adding quantitative diffusion-weighted imaging (DWI) to Ovarian-Adnexal Reporting and Data System (O-RADS) MRI to improve the diagnostic accuracy of the scoring system in a cohort of indeterminate adnexal lesions according to International Ovarian Tumor Analysis Group Simple Rules (IOTA-SR).
Methods and material
Seventy-nine women with 81 pelvic lesions classified as indeterminate according to IOTA-SR underwent 3-Tesla MRI with a conventional multiparametric protocol. DWI was quantitatively analyzed. Lesions were surgically removed or followed-up, according to a local protocol. Sensitivity, specificity, positive and negative predictive values and accuracy were determined for conventional multiparametric MRI and quantitative DWI-derived data.
Results
Twenty masses in 72 patients (27.8%) were malignant. An apparent diffusion coefficient (ADC) cut-off value of 1.30 × 10-3 mm2/s had 89% sensitivity and 80% specificity for malignancy. Overall, adding quantitative DWI to O-RADS MRI increased the specificity (98.08%, P<.001), positive predictive value (94.12%, P<.001), and accuracy (93.06%, P=.05). In the specific O-RADS MRI score 4 subgroup, an ADC cut-off value of 1.22 × 10-3 mm2/s had 86% sensitivity and 67% specificity for distinguishing benign from malignant lesions.
Conclusion
In IOTA-SR indeterminate adnexal lesions, quantitative DWI significantly improves the diagnostic performance of conventional multiparametric MRI in all O-RADS MRI score groups.
{"title":"El análisis cuantitativo de las imágenes potenciadas en difusión (DWI) mejora la precisión diagnóstica del sistema de puntuación O-RADS RM en lesiones anexiales indeterminadas","authors":"M. Arraiza , E. Chacón , A. Ezponda , D. Cano , J.Á. Mínguez , A. Benito , J.L. Alcázar","doi":"10.1016/j.rx.2024.01.010","DOIUrl":"10.1016/j.rx.2024.01.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite the overall high accuracy of the O-RADS MRI scoring system for characterization of indeterminate adnexal lesions, a non-negligible percentage of adnexal lesions remains indeterminate. Given this, the main objective of this study was to evaluate the value of adding quantitative diffusion-weighted imaging (DWI) to Ovarian-Adnexal Reporting and Data System (O-RADS) MRI to improve the diagnostic accuracy of the scoring system in a cohort of indeterminate adnexal lesions according to International Ovarian Tumor Analysis Group Simple Rules (IOTA-SR).</div></div><div><h3>Methods and material</h3><div>Seventy-nine women with 81 pelvic lesions classified as indeterminate according to IOTA-SR underwent 3-Tesla MRI with a conventional multiparametric protocol. DWI was quantitatively analyzed. Lesions were surgically removed or followed-up, according to a local protocol. Sensitivity, specificity, positive and negative predictive values and accuracy were determined for conventional multiparametric MRI and quantitative DWI-derived data.</div></div><div><h3>Results</h3><div>Twenty masses in 72 patients (27.8%) were malignant. An apparent diffusion coefficient (ADC) cut-off value of 1.30<!--> <!-->×<!--> <!-->10<sup>-3</sup> <!-->mm<sup>2</sup>/s had 89% sensitivity and 80% specificity for malignancy. Overall, adding quantitative DWI to O-RADS MRI increased the specificity (98.08%, <em>P</em><.001), positive predictive value (94.12%, <em>P</em><.001), and accuracy (93.06%, <em>P</em>=.05). In the specific O-RADS MRI score 4 subgroup, an ADC cut-off value of 1.22<!--> <!-->×<!--> <!-->10<sup>-3</sup> mm<sup>2</sup>/s had 86% sensitivity and 67% specificity for distinguishing benign from malignant lesions.</div></div><div><h3>Conclusion</h3><div>In IOTA-SR indeterminate adnexal lesions, quantitative DWI significantly improves the diagnostic performance of conventional multiparametric MRI in all O-RADS MRI score groups.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 309-318"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140758112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2024.11.003
E. Perdiguero Gil, B. Echániz Martínez, E. Bueno Vergara
This article highlights the role of radiologist Eduardo Amorós Martí (1888-1936) in the use of radioactivity for cancer treatment in Spain during the first third of the 20th century. Following the discovery of radium by the Curies in 1898, Amorós became interested in radiology and established his practice in Alicante. He acquired X-ray and radium equipment, contributing to the development of radiation therapy. He directed the Cancer Pavilion at the Provincial Hospital of Alicante, where he promoted the application of radiation in cancer treatment. Like other historical figures associated with radioactivity, his prolonged exposure deteriorated his health, leading to his premature death in 1936.
{"title":"Eduardo Amorós Martí: radiología y lucha anticancerosa en las primeras décadas del siglo xx","authors":"E. Perdiguero Gil, B. Echániz Martínez, E. Bueno Vergara","doi":"10.1016/j.rx.2024.11.003","DOIUrl":"10.1016/j.rx.2024.11.003","url":null,"abstract":"<div><div>This article highlights the role of radiologist Eduardo Amorós Martí (1888-1936) in the use of radioactivity for cancer treatment in Spain during the first third of the 20th century. Following the discovery of radium by the Curies in 1898, Amorós became interested in radiology and established his practice in Alicante. He acquired X-ray and radium equipment, contributing to the development of radiation therapy. He directed the Cancer Pavilion at the Provincial Hospital of Alicante, where he promoted the application of radiation in cancer treatment. Like other historical figures associated with radioactivity, his prolonged exposure deteriorated his health, leading to his premature death in 1936.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 365-369"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2025.02.008
A. Ezponda
{"title":"El papel de las altmétricas en la literatura científica","authors":"A. Ezponda","doi":"10.1016/j.rx.2025.02.008","DOIUrl":"10.1016/j.rx.2025.02.008","url":null,"abstract":"","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 251-252"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2024.11.006
M. Fresno Vallespir , I. Vázquez de las Heras , D. Gasior , A. Morales Rosa , X. Bargalló Castelló
Adenoid cystic carcinoma (ACC) of the breast is a rare tumour that represents less than 0.1% of breast carcinomas. It has a triple-negative phenotype; however, it is associated with a benign course, and both lymph node involvement and distant metastasis are rare. We present seven cases of ACC of the breast diagnosed in our centre. We describe their radiological characteristics, and specifically highlight the findings from magnetic resonance imaging.
{"title":"Hallazgos radiológicos del carcinoma adenoide quístico de mama","authors":"M. Fresno Vallespir , I. Vázquez de las Heras , D. Gasior , A. Morales Rosa , X. Bargalló Castelló","doi":"10.1016/j.rx.2024.11.006","DOIUrl":"10.1016/j.rx.2024.11.006","url":null,"abstract":"<div><div>Adenoid cystic carcinoma (ACC) of the breast is a rare tumour that represents less than 0.1% of breast carcinomas. It has a triple-negative phenotype; however, it is associated with a benign course, and both lymph node involvement and distant metastasis are rare. We present seven cases of ACC of the breast diagnosed in our centre. We describe their radiological characteristics, and specifically highlight the findings from magnetic resonance imaging.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 378-383"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2023.12.003
D. Herrán de la Gala , C. Cantolla Nates , M. Moris , R. Pellón Daben , J. Crespo del Pozo , F.J. González Sánchez , S. Sánchez Bernal
Gastric and duodenal ulcers (GDUs) are decreasing both in frequency and rate of mortality. However, GDUs with complications continue to have higher mortality rates and are seldom suspected in patients presenting with acute abdomen. Although upper endoscopy plays a central role in the diagnosis and treatment of GDUs, CT is crucial when serious complications appear, namely uncontrolled acute haemorrhage, perforation, organ penetration, or gastric obstruction. Radiologists have a special role to play in these situations, providing the diagnosis and extent of complications, thus contributing to decision making which can range from conservative management to endoscopic, surgical or interventional radiology procedures. The aim of our study is to describe the CT indications and protocols for patients with a suspected GDU with complications and present the main imaging findings for the different types of complications, while providing differential diagnoses.
{"title":"Evaluación mediante TC de las complicaciones de la úlcera gastroduodenal","authors":"D. Herrán de la Gala , C. Cantolla Nates , M. Moris , R. Pellón Daben , J. Crespo del Pozo , F.J. González Sánchez , S. Sánchez Bernal","doi":"10.1016/j.rx.2023.12.003","DOIUrl":"10.1016/j.rx.2023.12.003","url":null,"abstract":"<div><div>Gastric and duodenal ulcers (GDUs) are decreasing both in frequency and rate of mortality. However, GDUs with complications continue to have higher mortality rates and are seldom suspected in patients presenting with acute abdomen. Although upper endoscopy plays a central role in the diagnosis and treatment of GDUs, CT is crucial when serious complications appear, namely uncontrolled acute haemorrhage, perforation, organ penetration, or gastric obstruction. Radiologists have a special role to play in these situations, providing the diagnosis and extent of complications, thus contributing to decision making which can range from conservative management to endoscopic, surgical or interventional radiology procedures. The aim of our study is to describe the CT indications and protocols for patients with a suspected GDU with complications and present the main imaging findings for the different types of complications, while providing differential diagnoses.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 343-356"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2024.04.005
E. Baettig , M.F. Molina-Centelles , A. Amr-Rey , N. Mancheño-Franch , C. Muñoz-Núñez
Pulmonary neuroendocrine cells, which constitute a small percentage (0.4%) of airway epithelial cells, play a key role in hypoxia detection, epithelial growth and regeneration, and in lung organogenesis through the synthesis and secretion of amines and peptides. Lesions resulting from pulmonary neuroendocrine cell proliferation range from benign and indolent to malignant and highly aggressive. The recently updated WHO classification of pulmonary neuroendocrine neoplasms includes typical and atypical carcinoid tumours as well as high-grade neuroendocrine carcinomas: large cell neuroendocrine carcinomas and small cell carcinomas. This classification also recognises a condition known as diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) as a distinct entity. Radiologists need to become familiar with these pathologies as the symptoms often lack specificity, and thus imaging plays a crucial role in diagnosis. An understanding of the correlation between the radiological and pathological examinations of these pathologies can enhance our awareness of the wide spectrum of imaging manifestations.
{"title":"Las células neuroendocrinas en el pulmón: Espectro de patologías y su correlación radiopatológica","authors":"E. Baettig , M.F. Molina-Centelles , A. Amr-Rey , N. Mancheño-Franch , C. Muñoz-Núñez","doi":"10.1016/j.rx.2024.04.005","DOIUrl":"10.1016/j.rx.2024.04.005","url":null,"abstract":"<div><div>Pulmonary neuroendocrine cells, which constitute a small percentage (0.4%) of airway epithelial cells, play a key role in hypoxia detection, epithelial growth and regeneration, and in lung organogenesis through the synthesis and secretion of amines and peptides. Lesions resulting from pulmonary neuroendocrine cell proliferation range from benign and indolent to malignant and highly aggressive. The recently updated WHO classification of pulmonary neuroendocrine neoplasms includes typical and atypical carcinoid tumours as well as high-grade neuroendocrine carcinomas: large cell neuroendocrine carcinomas and small cell carcinomas. This classification also recognises a condition known as diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) as a distinct entity. Radiologists need to become familiar with these pathologies as the symptoms often lack specificity, and thus imaging plays a crucial role in diagnosis. An understanding of the correlation between the radiological and pathological examinations of these pathologies can enhance our awareness of the wide spectrum of imaging manifestations.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 357-364"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2024.01.007
M. Pérez Laencina , J.M. Plasencia Martínez , M. Sánchez Canales , C. Jiménez Pulido , R. Rodríguez Mondéjar , L. Martínez Encarnación , C. García Hidalgo , D. Galdo Galián , P. Hernández Madrid , L. Chico Caballero , E. Guillén García , M.N. Plasencia Martínez , S. Martínez Romero , J. García Molina , J.M. García Santos
Introduction
Our objective is to evaluate how useful an artificial intelligence (AI) tool is to chest radiograph readers with various levels of expertise for the diagnosis of COVID-19 pneumonia when the tool has been trained on a non-COVID-19 pneumonia pathology.
Methods
Data was collected for patients who had previously undergone a chest radiograph and digital tomosynthesis due to suspected COVID-19 pneumonia. The gold standard consisted of the readings of two expert radiologists who assessed the presence and distribution of COVID-19 pneumonia on the images. Six medical students, two radiology trainees, and two other expert thoracic radiologists participated as additional readers. Two radiograph readings and a third supported by the AI Thoracic Care Suite tool were performed. COVID-19 pneumonia distribution and probability were assessed along with the contribution made by AI. Agreement and diagnostic performance were analysed.
Results
The sample consisted of 113 cases, of which 56 displayed lung opacities, 52.2% were female, and the mean age was 50.70 ± 14.9. Agreement with the gold standard differed between students, trainees, and radiologists. There was a non-significant improvement for four of the six students when AI was used. The use of AI by students did not improve the COVID-19 pneumonia diagnostic performance but it did reduce the difference in diagnostic performance with the more expert radiologists. Furthermore, it had more influence on the interpretation of mild pneumonia than severe pneumonia and normal radiograph findings. AI resolved more doubts than it generated, especially among students (31.30 vs 8.32%), followed by trainees (14.45 vs 5.7%) and radiologists (10.05% vs 6.15%).
Conclusion
For expert and lesser experienced radiologists, this commercial AI tool has shown no impact on chest radiograph readings of patients with suspected COVID-19 pneumonia. However, it aided the assessment of inexperienced readers and in cases of mild pneumonia.
{"title":"Usar una herramienta comercial de inteligencia artificial no entrenada para COVID-19 mejora ligeramente la interpretación de las radiografías con neumonía COVID-19, especialmente entre lectores inexpertos","authors":"M. Pérez Laencina , J.M. Plasencia Martínez , M. Sánchez Canales , C. Jiménez Pulido , R. Rodríguez Mondéjar , L. Martínez Encarnación , C. García Hidalgo , D. Galdo Galián , P. Hernández Madrid , L. Chico Caballero , E. Guillén García , M.N. Plasencia Martínez , S. Martínez Romero , J. García Molina , J.M. García Santos","doi":"10.1016/j.rx.2024.01.007","DOIUrl":"10.1016/j.rx.2024.01.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Our objective is to evaluate how useful an artificial intelligence (AI) tool is to chest radiograph readers with various levels of expertise for the diagnosis of COVID-19 pneumonia when the tool has been trained on a non-COVID-19 pneumonia pathology.</div></div><div><h3>Methods</h3><div>Data was collected for patients who had previously undergone a chest radiograph and digital tomosynthesis due to suspected COVID-19 pneumonia. The gold standard consisted of the readings of two expert radiologists who assessed the presence and distribution of COVID-19 pneumonia on the images. Six medical students, two radiology trainees, and two other expert thoracic radiologists participated as additional readers. Two radiograph readings and a third supported by the AI Thoracic Care Suite tool were performed. COVID-19 pneumonia distribution and probability were assessed along with the contribution made by AI. Agreement and diagnostic performance were analysed.</div></div><div><h3>Results</h3><div>The sample consisted of 113 cases, of which 56 displayed lung opacities, 52.2% were female, and the mean age was 50.70<!--> <!-->±<!--> <!-->14.9. Agreement with the gold standard differed between students, trainees, and radiologists. There was a non-significant improvement for four of the six students when AI was used. The use of AI by students did not improve the COVID-19 pneumonia diagnostic performance but it did reduce the difference in diagnostic performance with the more expert radiologists. Furthermore, it had more influence on the interpretation of mild pneumonia than severe pneumonia and normal radiograph findings. AI resolved more doubts than it generated, especially among students (31.30 vs 8.32%), followed by trainees (14.45 vs 5.7%) and radiologists (10.05% vs 6.15%).</div></div><div><h3>Conclusion</h3><div>For expert and lesser experienced radiologists, this commercial AI tool has shown no impact on chest radiograph readings of patients with suspected COVID-19 pneumonia. However, it aided the assessment of inexperienced readers and in cases of mild pneumonia.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 273-286"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.rx.2023.11.010
J. Azcona Sáenz , C.V. Martinez Stocker , E.N. Arenas Rivera , S. Marsico , E. Arizaga Batiz , R. Alcantara Souza
Male nipple discharge is uncommon and highly associated with malignancy. However, it can also be due to benign processes. In addition to physical examination, all patients should undergo a radiological examination with mammography and/or ultrasound. Furthermore, we propose the use of contrast-enhanced mammography (CEM) in cases of suspicious nipple discharge due to the high negative predictive value of this technique, potentially reducing the number of unnecessary biopsies. The aim of this article is to review the imaging findings of the most common causes of male nipple discharge, both benign and malignant. Additionally, we would like to share our experience with the use of CEM in studying this condition.
{"title":"Revisión radiológica de la secreción mamaria en el varón","authors":"J. Azcona Sáenz , C.V. Martinez Stocker , E.N. Arenas Rivera , S. Marsico , E. Arizaga Batiz , R. Alcantara Souza","doi":"10.1016/j.rx.2023.11.010","DOIUrl":"10.1016/j.rx.2023.11.010","url":null,"abstract":"<div><div>Male nipple discharge is uncommon and highly associated with malignancy. However, it can also be due to benign processes. In addition to physical examination, all patients should undergo a radiological examination with mammography and/or ultrasound. Furthermore, we propose the use of contrast-enhanced mammography (CEM) in cases of suspicious nipple discharge due to the high negative predictive value of this technique, potentially reducing the number of unnecessary biopsies. The aim of this article is to review the imaging findings of the most common causes of male nipple discharge, both benign and malignant. Additionally, we would like to share our experience with the use of CEM in studying this condition.</div></div>","PeriodicalId":31509,"journal":{"name":"RADIOLOGIA","volume":"67 3","pages":"Pages 319-330"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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