BACKGROUND: Development and testing of drugs with regenerative and anti-inflammatory properties. It is advisable using them in keratopathy development and impairments of trophic processes, at the action of preservatives against the background of long-term local IOP-lowering therapy for glaucoma, as well as in the presence of a surgical wound in the area of the procedure, the last causing discomfort in many patients, foreign body sensation, and ocular irritation during the postoperative period in glaucoma treatment. AIM: To evaluate the effect of ophthalmic drug films (ODF) with 6-methyl-3- (thietan-3-yl)uracil and methyluracil on the thickness of the corneal epithelium after experimental chemical burn. MATERIALS AND METHODS: A histomorphological analysis of the cornea of 17 rabbits (34 eyes) of the Chinchilla breed after experimental chemical burn was carried out, the wound healing and keratoprotective properties of ophthalmic drug films were evaluated. Ophthalmic drug films with 6-methyl-3-(thietan-3-yl)uracil were placed in right eyes of 15 rabbits, and those with methyluracil were placed in left eyes of same rabbits. Two rabbits (4 eyes) served as control: their right eyes were left without wound healing therapy, while left eyes received dexpanthenol 5% gel (Corneregel) 4 times a day. The animals were followed-up for 21 days, morphological changes in the cornea were assessed on the 2nd, 7th, 14th and 21st days of the study. RESULTS: Different results were obtained depending on the ODF used. The use of ODF with methyluracil on days 27 led to an increase in the thickness and the number of epithelial layers compared to ophthalmic drug films with 6-methyl-3-(thietan-3-yl)uracil, where epithelial reactivity was observed by 14 days. On the 21st day of follow-up, the microscopic picture of the cornea in the right and the left eyes was characterized by total restoration and healing of the corneal epithelium. CONCLUSIONS: Ophthalmic drug films therapy with methyluracil and 6-methyl-3-(thietan-3-yl)uracil leads to histologically correct and rapid epithelialization of the cornea after a chemical burn.
{"title":"Effect of ophthalmic drug films with methyluracil and 6-methyl-3-(thietan-3-yl)uracil on the thickness of the corneal epithelium","authors":"A. F. Gabdrakhmanova, Sadyrbek A. Kurbanov","doi":"10.17816/ov81549","DOIUrl":"https://doi.org/10.17816/ov81549","url":null,"abstract":"BACKGROUND: Development and testing of drugs with regenerative and anti-inflammatory properties. It is advisable using them in keratopathy development and impairments of trophic processes, at the action of preservatives against the background of long-term local IOP-lowering therapy for glaucoma, as well as in the presence of a surgical wound in the area of the procedure, the last causing discomfort in many patients, foreign body sensation, and ocular irritation during the postoperative period in glaucoma treatment. \u0000AIM: To evaluate the effect of ophthalmic drug films (ODF) with 6-methyl-3- (thietan-3-yl)uracil and methyluracil on the thickness of the corneal epithelium after experimental chemical burn. \u0000MATERIALS AND METHODS: A histomorphological analysis of the cornea of 17 rabbits (34 eyes) of the Chinchilla breed after experimental chemical burn was carried out, the wound healing and keratoprotective properties of ophthalmic drug films were evaluated. Ophthalmic drug films with 6-methyl-3-(thietan-3-yl)uracil were placed in right eyes of 15 rabbits, and those with methyluracil were placed in left eyes of same rabbits. Two rabbits (4 eyes) served as control: their right eyes were left without wound healing therapy, while left eyes received dexpanthenol 5% gel (Corneregel) 4 times a day. The animals were followed-up for 21 days, morphological changes in the cornea were assessed on the 2nd, 7th, 14th and 21st days of the study. \u0000RESULTS: Different results were obtained depending on the ODF used. The use of ODF with methyluracil on days 27 led to an increase in the thickness and the number of epithelial layers compared to ophthalmic drug films with 6-methyl-3-(thietan-3-yl)uracil, where epithelial reactivity was observed by 14 days. On the 21st day of follow-up, the microscopic picture of the cornea in the right and the left eyes was characterized by total restoration and healing of the corneal epithelium. \u0000CONCLUSIONS: Ophthalmic drug films therapy with methyluracil and 6-methyl-3-(thietan-3-yl)uracil leads to histologically correct and rapid epithelialization of the cornea after a chemical burn.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42842594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: One of the problems in the diagnosis and treatment of pellucid marginal degeneration of the cornea is the difficulty of systematizing its manifestations due to the lack of classification. This is due to the low frequency of pellucid marginal degeneration in the structure of primary keratectasia, the main type of which is keratoconus. The developed classifications of keratoconus cannot be fully applied to pellucid marginal degeneration. AIM: The aim was to develop a classification of pellucid marginal degeneration based on investigation of relationship between functional and refractive changes. MATERIALS AND METHODS: The study included 42 people (42 eyes) with pellucid marginal degeneration. Keratometry and refractometry were performed, uncorrected and best corrected visual acuity, as well as cylindrical and spherical components of subjective refraction were studied, and retinal visual acuity was determined. The 1st group 12 patients (12 eyes) with fully corrected induced ametropia (best corrected visual acuity 0.8), the 2nd group 17 patients (17 eyes) with partially corrected induced ametropia (0.8 and 0.3), the 3rd group 13 patients (13 eyes) with uncorrected induced ametropia (0.3). RESULTS: To develop a clinical classification of pellucid marginal degeneration by stages, we selected: the values of corneal astigmatism, best corrected visual acuity and Index of difference between the values of maximum and minimum keratometry (K), all of which had good separation of obtained data, and their demarcate values in groups. CONCLUSION: The study showed the presence of relationship between functional and refractive changes indices of eyes with pellucid marginal degeneration. The leading parameters of refractive status, objectively determining the value of best corrected visual acuity, are induced corneal astigmatism and K. The developed classification of pellucid marginal degeneration is easy to use and makes it possible to determine the stage of keratectasia even if there is only induced corneal astigmatism or K values.
{"title":"Pellucid marginal degeneration classification development based on investigation of relationship between functional and refractive changes","authors":"Irina V. Vasilieva, S. V. Kostenev, A. Vasiliev","doi":"10.17816/ov79626","DOIUrl":"https://doi.org/10.17816/ov79626","url":null,"abstract":"BACKGROUND: One of the problems in the diagnosis and treatment of pellucid marginal degeneration of the cornea is the difficulty of systematizing its manifestations due to the lack of classification. This is due to the low frequency of pellucid marginal degeneration in the structure of primary keratectasia, the main type of which is keratoconus. The developed classifications of keratoconus cannot be fully applied to pellucid marginal degeneration. \u0000AIM: The aim was to develop a classification of pellucid marginal degeneration based on investigation of relationship between functional and refractive changes. \u0000MATERIALS AND METHODS: The study included 42 people (42 eyes) with pellucid marginal degeneration. Keratometry and refractometry were performed, uncorrected and best corrected visual acuity, as well as cylindrical and spherical components of subjective refraction were studied, and retinal visual acuity was determined. The 1st group 12 patients (12 eyes) with fully corrected induced ametropia (best corrected visual acuity 0.8), the 2nd group 17 patients (17 eyes) with partially corrected induced ametropia (0.8 and 0.3), the 3rd group 13 patients (13 eyes) with uncorrected induced ametropia (0.3). \u0000RESULTS: To develop a clinical classification of pellucid marginal degeneration by stages, we selected: the values of corneal astigmatism, best corrected visual acuity and Index of difference between the values of maximum and minimum keratometry (K), all of which had good separation of obtained data, and their demarcate values in groups. \u0000CONCLUSION: The study showed the presence of relationship between functional and refractive changes indices of eyes with pellucid marginal degeneration. The leading parameters of refractive status, objectively determining the value of best corrected visual acuity, are induced corneal astigmatism and K. The developed classification of pellucid marginal degeneration is easy to use and makes it possible to determine the stage of keratectasia even if there is only induced corneal astigmatism or K values.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44737286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitalii V. Potemkin, O. A. Marchenko, E. Goltsman, L. K. Anikina, Ekaterina K. Gladysheva
Non-suicidal self-inflicted injuries are encountered in the practice of doctors of all specialties. Within the framework of this article, a case of surgical treatment of a female patient with pathomimia and lagophthalmos will be presented.
{"title":"Pathomimia in a practice of an ophthalmologist","authors":"Vitalii V. Potemkin, O. A. Marchenko, E. Goltsman, L. K. Anikina, Ekaterina K. Gladysheva","doi":"10.17816/ov101088","DOIUrl":"https://doi.org/10.17816/ov101088","url":null,"abstract":"Non-suicidal self-inflicted injuries are encountered in the practice of doctors of all specialties. Within the framework of this article, a case of surgical treatment of a female patient with pathomimia and lagophthalmos will be presented.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45690909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Comment of the Editor-in-chief on the article by Potemkin V.V., Marchenko O.A., Goltsman E.V., Anikina L.K., Gladysheva E.K. Pathomimia in the practice of an ophthalmologist, 2021, V. 14, No. 4.
{"title":"Comment on the article “Pathomimia in a practice of an ophthalmologist”","authors":"D. V. Davydov","doi":"10.17816/ov101588","DOIUrl":"https://doi.org/10.17816/ov101588","url":null,"abstract":"Comment of the Editor-in-chief on the article by Potemkin V.V., Marchenko O.A., Goltsman E.V., Anikina L.K., Gladysheva E.K. Pathomimia in the practice of an ophthalmologist, 2021, V. 14, No. 4.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43356502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ivachev, I. P. Denisova, E. Anisimova, Mohammed A. Tanash
BACKGROUND: A lot of patients are admitted to hospital with mature cataract, this raises the risk of complications and makes longer the rehabilitation period. AIM: To identify the reasons for admission of patients with advanced forms of cataract, and associated factors complicating the surgery in these patients. MATERIALS AND METHODS: 674 operated patients with various degrees of lens opacity; out of them, 145 (21.5%) cases were with mature cataracts. RESULTS: 95.2% (n = 138) of patients did not seek ophthalmological attention, 4.8% (n = 7) of patients noted that they were referred late due to the fault of their local ophthalmologists. In 31.9% of cases (138 patients), the main cause was absence of an ophthalmologist in the outpatient polyclinic. The patients lack of funds for the purchase of an intraocular lens (IOL) was the reason in 26.1%. In 15.2% of cases, patients refused surgery due to domestic problems. 14.5% of patients lived with the idea of self-restoration of vision. Low transportable patients amounted to 5.1%; in 4.3% of cases, elderly patients did not perceive the loss of spatial vision in one eye. Remaining 2.9% of patients from the psychoneurological dispensary were admitted for phacoemulsification having intumescent cataracts. The maturity of the cataract leads to certain intraoperative difficulties, which are accompanied by additional manipulations, increasing the risk of complications and the duration of procedures. These include: pupil diameter less than 5 mm 37.2%; pseudoexfoliation syndrome 22.8%; the presence of an advanced intumescent cataract in 36.6%; shallow anterior chamber 44.8%; lens subluxation 24.1%; atrophy of the pupillary margin 39.3%; fibrosis of the posterior capsule diagnosed intraoperatively 13.8%. Phacoemulsification was carried out using the Optimed phaco machine (Russia). For an immature cataract, we used a power of 30% and the time spent was 2.73 seconds; with a mature one 60% and 9.96 seconds respectively. The best corrected visual acuity on Day 1 after cataract extraction was 0.53 0.27, on Day 7 0.73 0.22, after 3 months 0.76 0.25. CONCLUSIONS: Mature cataract is encountered in 21.5% of all cataract surgeries. In 95.2% of cases, patients themselves did not seek medical help. The maturity of the cataract led to certain factors complicating the course of surgery: pupil diameter less than 5 mm, swelling of the lens cortical masses, shallow anterior chamber, lens subluxation, atrophy of the pigment border of the iris. The ultrasound power used in the mature cataract surgery was 2 times higher than in that of immature ones; and the operating time of ultrasound increased by 3.6 times.
{"title":"Why are patients with mature cataract admitted to hospital? Challenges for cataract surgery","authors":"E. Ivachev, I. P. Denisova, E. Anisimova, Mohammed A. Tanash","doi":"10.17816/ov84019","DOIUrl":"https://doi.org/10.17816/ov84019","url":null,"abstract":"BACKGROUND: A lot of patients are admitted to hospital with mature cataract, this raises the risk of complications and makes longer the rehabilitation period. \u0000AIM: To identify the reasons for admission of patients with advanced forms of cataract, and associated factors complicating the surgery in these patients. \u0000MATERIALS AND METHODS: 674 operated patients with various degrees of lens opacity; out of them, 145 (21.5%) cases were with mature cataracts. \u0000RESULTS: 95.2% (n = 138) of patients did not seek ophthalmological attention, 4.8% (n = 7) of patients noted that they were referred late due to the fault of their local ophthalmologists. In 31.9% of cases (138 patients), the main cause was absence of an ophthalmologist in the outpatient polyclinic. The patients lack of funds for the purchase of an intraocular lens (IOL) was the reason in 26.1%. In 15.2% of cases, patients refused surgery due to domestic problems. 14.5% of patients lived with the idea of self-restoration of vision. Low transportable patients amounted to 5.1%; in 4.3% of cases, elderly patients did not perceive the loss of spatial vision in one eye. Remaining 2.9% of patients from the psychoneurological dispensary were admitted for phacoemulsification having intumescent cataracts. The maturity of the cataract leads to certain intraoperative difficulties, which are accompanied by additional manipulations, increasing the risk of complications and the duration of procedures. These include: pupil diameter less than 5 mm 37.2%; pseudoexfoliation syndrome 22.8%; the presence of an advanced intumescent cataract in 36.6%; shallow anterior chamber 44.8%; lens subluxation 24.1%; atrophy of the pupillary margin 39.3%; fibrosis of the posterior capsule diagnosed intraoperatively 13.8%. Phacoemulsification was carried out using the Optimed phaco machine (Russia). For an immature cataract, we used a power of 30% and the time spent was 2.73 seconds; with a mature one 60% and 9.96 seconds respectively. The best corrected visual acuity on Day 1 after cataract extraction was 0.53 0.27, on Day 7 0.73 0.22, after 3 months 0.76 0.25. \u0000CONCLUSIONS: Mature cataract is encountered in 21.5% of all cataract surgeries. In 95.2% of cases, patients themselves did not seek medical help. The maturity of the cataract led to certain factors complicating the course of surgery: pupil diameter less than 5 mm, swelling of the lens cortical masses, shallow anterior chamber, lens subluxation, atrophy of the pigment border of the iris. The ultrasound power used in the mature cataract surgery was 2 times higher than in that of immature ones; and the operating time of ultrasound increased by 3.6 times.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47838902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. M. Popov, A. Kulikov, S. V. Churashov, I. O. Gavrilyuk, Elisaveta N. Egorova, Anastasiya I. Abbasova
BACKGROUND: In recent years, autologous serum has been increasingly used in the treatment of macular hole. The study carried out a biological analysis of autologous serum obtained by various methods. AIM: The aim of the investigation is to compare the cellular and biochemical composition of autologous serum obtained using different methods for use in the macular hole treatment. MATERIALS AND METHODS: The study of the number of platelets, leukocytes and fibrinogen level in the blood serum of 24 patients obtained by centrifugation in original systems for harvesting autologous serum and laboratory test tubes was performed. RESULTS: The indices of P-PRP obtained in the Arthrex ACP system and in a laboratory test tube do not statistically differ in quantitative indices of fibrinogen and platelets (p 0.05), and differ in the content of leukocytes (p 0.05) in the direction of increasing the number of leukocytes in the substrate obtained in a laboratory test tube. The indicators of L-PRP obtained in the Ycellbio-Kit system and in a laboratory test tube do not statistically differ in the amount of fibrinogen (p 0.05) and differ in the content of platelets and leukocytes (p 0.05) in the direction of decreasing the concentration of leukocytes and platelets in the autologous serum obtained in a laboratory test tube. CONCLUSIONS: Currently, autologous serum obtained in the Arthrex ACP system is of great interest for macular hole surgery due to the minimal content of leukocytes, the closed character of the system, and the best coagulation properties of the substrate obtained. Laboratory test tubes may be considered a more affordable alternative for the production of autologous serum (P-PRP) for the treatment of macular hole. The autologous serum (L-PRP) obtained in the Ycellbio-Kit system and in a laboratory test tube is less suitable for macular hole surgery according to its composition.
{"title":"Comparison of indicators of autologous serum obtained by different methods and used for the treatment of macular hole","authors":"E. M. Popov, A. Kulikov, S. V. Churashov, I. O. Gavrilyuk, Elisaveta N. Egorova, Anastasiya I. Abbasova","doi":"10.17816/ov89413","DOIUrl":"https://doi.org/10.17816/ov89413","url":null,"abstract":"BACKGROUND: In recent years, autologous serum has been increasingly used in the treatment of macular hole. The study carried out a biological analysis of autologous serum obtained by various methods. \u0000AIM: The aim of the investigation is to compare the cellular and biochemical composition of autologous serum obtained using different methods for use in the macular hole treatment. \u0000MATERIALS AND METHODS: The study of the number of platelets, leukocytes and fibrinogen level in the blood serum of 24 patients obtained by centrifugation in original systems for harvesting autologous serum and laboratory test tubes was performed. \u0000RESULTS: The indices of P-PRP obtained in the Arthrex ACP system and in a laboratory test tube do not statistically differ in quantitative indices of fibrinogen and platelets (p 0.05), and differ in the content of leukocytes (p 0.05) in the direction of increasing the number of leukocytes in the substrate obtained in a laboratory test tube. The indicators of L-PRP obtained in the Ycellbio-Kit system and in a laboratory test tube do not statistically differ in the amount of fibrinogen (p 0.05) and differ in the content of platelets and leukocytes (p 0.05) in the direction of decreasing the concentration of leukocytes and platelets in the autologous serum obtained in a laboratory test tube. \u0000CONCLUSIONS: Currently, autologous serum obtained in the Arthrex ACP system is of great interest for macular hole surgery due to the minimal content of leukocytes, the closed character of the system, and the best coagulation properties of the substrate obtained. Laboratory test tubes may be considered a more affordable alternative for the production of autologous serum (P-PRP) for the treatment of macular hole. The autologous serum (L-PRP) obtained in the Ycellbio-Kit system and in a laboratory test tube is less suitable for macular hole surgery according to its composition.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42528585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Strabismus as a pathological condition complicating the visual function and affecting the behavioral functions of children is often in the center of attention of numerous studies. The presence of regional differences in the strabismus prevalence makes this problem a relevant to study issue in the regions of Azerbaijan. AIM: To assess the prevalence rate of strabismus among children depending on the settlement type. MATERIALS AND METHODS: A prospective observation of a sample of children aged 519 years was carried out; the sample size was determined taking into account the size of the margin of sampling error less than 5%. 300 children at the age 59, 1014, 1519 years (150 boys and 150 girls) in a large town (Ganja) and rural settlements of Ganja-Gazakh region (2700 children in total) have been observed. In all children, an ophthalmologic examination was performed by specialists of the mobile team of the National Ophthalmological Center named after academician Z. Aliyeva. RESULTS: Strabismus was found in children aged 5-19 years in 4.6 0.7% of cases in a large town and in 2.7 0.5% of cases in rural settlements. Significant differences of prevalence rate of strabismus by age and gender were not confirmed. CONCLUSIONS: In the region, the incidence of strabismus among children aged 519 years was 3.8 0.4%. In a large town, the risk of strabismus among children is high. In children with strabismus, refractive errors and perinatal conditions (prematurity) are often found.
{"title":"The level of prevalence and risk factors of strabismus among children and adolescents, depending on the type of settlements in the Ganja-Gazakh economic district (Azerbaijan)","authors":"Y. Abdiyeva","doi":"10.17816/ov89720","DOIUrl":"https://doi.org/10.17816/ov89720","url":null,"abstract":"BACKGROUND: Strabismus as a pathological condition complicating the visual function and affecting the behavioral functions of children is often in the center of attention of numerous studies. The presence of regional differences in the strabismus prevalence makes this problem a relevant to study issue in the regions of Azerbaijan. \u0000AIM: To assess the prevalence rate of strabismus among children depending on the settlement type. \u0000MATERIALS AND METHODS: A prospective observation of a sample of children aged 519 years was carried out; the sample size was determined taking into account the size of the margin of sampling error less than 5%. 300 children at the age 59, 1014, 1519 years (150 boys and 150 girls) in a large town (Ganja) and rural settlements of Ganja-Gazakh region (2700 children in total) have been observed. In all children, an ophthalmologic examination was performed by specialists of the mobile team of the National Ophthalmological Center named after academician Z. Aliyeva. \u0000RESULTS: Strabismus was found in children aged 5-19 years in 4.6 0.7% of cases in a large town and in 2.7 0.5% of cases in rural settlements. Significant differences of prevalence rate of strabismus by age and gender were not confirmed. \u0000CONCLUSIONS: In the region, the incidence of strabismus among children aged 519 years was 3.8 0.4%. In a large town, the risk of strabismus among children is high. In children with strabismus, refractive errors and perinatal conditions (prematurity) are often found.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47244870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia N. Sadovnikova, V. Brzheskiy, N. V. Prisich, M. A. Zertsalova, Andrei Yu. Baranov
BACKGROUND: In many types of pediatric glaucoma, there is no clear algorithm for surgical management. In these situations, the procedure of choice can be the implantation of various types of drainage devices. AIM: To evaluate the outcomes of Ahmed Glaucoma Valve implantation in refractory pediatric glaucoma. MATERIALS AND METHODS: The treatment results of 52 children (67 eyes) aged 1 month 17 years (6.6 0.6 years) with unsuccessfully operated primary congenital glaucoma, with glaucoma associated with congenital anomalies of the eyeball, with secondary glaucoma were analyzed. The surgery was considered to be effective when stable intraocular pressure (IOP) was achieved, there were no complications, and no need for repeated interventions. RESULTS: The effect of surgery was maintained for 6 months in 97% of patients, but after 1, 2 and 3 years it decreased to 91.8%, 82%, and 73.9%, respectively, and to 42.8% after 7 years. Postoperative complications included filtering bleb encapsulation (25.3%), iris retraction to the tube with pupil dislocation (4.5%); ciliochoroidal detachment (4.5%); cataract (3.0%), conjunctival erosion with tube eruption (4.5%), endophthalmitis (1.5%), retinal detachment (6.0%), tube retraction (1.5%), hyphema (3.0%). The risk factors for an unfavorable outcome of the procedure were: an increase in the anteroposterior axis of the eyeball length by 20% or more compared to the age norm, IOP at the time of the surgery higher than 32 mm Hg, as well as previous antiglaucoma filtering procedures. CONCLUSIONS: The implantation of the drainage device Ahmed Glaucoma Valve is indicated for refractory pediatric glaucoma in case of ineffectiveness of previous surgeries. However, it is necessary to take into account the decrease in the effectiveness of the device over time, which, combined with the possibility of complications, requires long-term follow-up of patients.
{"title":"Outcomes of Ahmed glaucoma valve implantation in pediatric glaucoma","authors":"Natalia N. Sadovnikova, V. Brzheskiy, N. V. Prisich, M. A. Zertsalova, Andrei Yu. Baranov","doi":"10.17816/ov101112","DOIUrl":"https://doi.org/10.17816/ov101112","url":null,"abstract":"BACKGROUND: In many types of pediatric glaucoma, there is no clear algorithm for surgical management. In these situations, the procedure of choice can be the implantation of various types of drainage devices. \u0000AIM: To evaluate the outcomes of Ahmed Glaucoma Valve implantation in refractory pediatric glaucoma. \u0000MATERIALS AND METHODS: The treatment results of 52 children (67 eyes) aged 1 month 17 years (6.6 0.6 years) with unsuccessfully operated primary congenital glaucoma, with glaucoma associated with congenital anomalies of the eyeball, with secondary glaucoma were analyzed. The surgery was considered to be effective when stable intraocular pressure (IOP) was achieved, there were no complications, and no need for repeated interventions. \u0000RESULTS: The effect of surgery was maintained for 6 months in 97% of patients, but after 1, 2 and 3 years it decreased to 91.8%, 82%, and 73.9%, respectively, and to 42.8% after 7 years. Postoperative complications included filtering bleb encapsulation (25.3%), iris retraction to the tube with pupil dislocation (4.5%); ciliochoroidal detachment (4.5%); cataract (3.0%), conjunctival erosion with tube eruption (4.5%), endophthalmitis (1.5%), retinal detachment (6.0%), tube retraction (1.5%), hyphema (3.0%). The risk factors for an unfavorable outcome of the procedure were: an increase in the anteroposterior axis of the eyeball length by 20% or more compared to the age norm, IOP at the time of the surgery higher than 32 mm Hg, as well as previous antiglaucoma filtering procedures. \u0000CONCLUSIONS: The implantation of the drainage device Ahmed Glaucoma Valve is indicated for refractory pediatric glaucoma in case of ineffectiveness of previous surgeries. However, it is necessary to take into account the decrease in the effectiveness of the device over time, which, combined with the possibility of complications, requires long-term follow-up of patients.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46854039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. A. Konovalov, Dmitrii V. Davydov, D. A. Lezhnev
BACKGROUND: The most effective method of surgical treatment of lipogenic and mixed forms of edematous exophthalmos is currently the internal orbital decompression. During this surgical procedure, the excessive pathologically altered adipose tissue is removed from the external and the internal surgical spaces of the orbit. Many scientists are developing methods for calculating the volume of orbital fat, but the question on developing a method for predicted exophthalmos after internal orbital decompression, which could be used without attracting additional equipment and software, is easy to learn and does not require a long calculation time, remains actual. This method has to take into account the individual features of the patients orbital structure and be used for calculations in the bilateral proptosis correction. AIM: To develop and evaluate the effectiveness of a new method for calculating the eyeball position after orbital decompression. MATERIALS AND METHODS: 64 patients (126 orbits) with lipogenic and mixed forms of endocrine ophthalmopathy were examined. All patients underwent internal orbital decompression, during which the orbital fat was removed, the volume of which was calculated according to the developed original method. Patients underwent ophthalmological examination and MSCT before surgery and 6 months after it. . RESULTS: As a result of orbital decompression in the examined group, a decrease in proptosis was observed in all patients, and the exophthalmos calculated by the method corresponded to the eyeball position in patients in 6 months after surgery. The level of statistical significance of the planned postoperative eyeball position in relation to the actual postoperative exophthalmos calculated according to the Students t-test was 0.98 (p 0.05), that is, it can be argued that the groups do not differ, and no statistically significant differences were found. CONCLUSIONS: The developed method for calculating the estimated postoperative exophthalmos is effective without using additional software. This technique allows you to achieve a symmetrical eyeball position in the postoperative period and to reduce the risk of complications.
{"title":"The method of the exophthalmos value predicted calculation when planning the orbital decompression procedure in patients with endocrine ophthalmopathy","authors":"K. A. Konovalov, Dmitrii V. Davydov, D. A. Lezhnev","doi":"10.17816/ov88012","DOIUrl":"https://doi.org/10.17816/ov88012","url":null,"abstract":"BACKGROUND: The most effective method of surgical treatment of lipogenic and mixed forms of edematous exophthalmos is currently the internal orbital decompression. During this surgical procedure, the excessive pathologically altered adipose tissue is removed from the external and the internal surgical spaces of the orbit. Many scientists are developing methods for calculating the volume of orbital fat, but the question on developing a method for predicted exophthalmos after internal orbital decompression, which could be used without attracting additional equipment and software, is easy to learn and does not require a long calculation time, remains actual. This method has to take into account the individual features of the patients orbital structure and be used for calculations in the bilateral proptosis correction. \u0000AIM: To develop and evaluate the effectiveness of a new method for calculating the eyeball position after orbital decompression. \u0000MATERIALS AND METHODS: 64 patients (126 orbits) with lipogenic and mixed forms of endocrine ophthalmopathy were examined. All patients underwent internal orbital decompression, during which the orbital fat was removed, the volume of which was calculated according to the developed original method. Patients underwent ophthalmological examination and MSCT before surgery and 6 months after it. . \u0000RESULTS: As a result of orbital decompression in the examined group, a decrease in proptosis was observed in all patients, and the exophthalmos calculated by the method corresponded to the eyeball position in patients in 6 months after surgery. The level of statistical significance of the planned postoperative eyeball position in relation to the actual postoperative exophthalmos calculated according to the Students t-test was 0.98 (p 0.05), that is, it can be argued that the groups do not differ, and no statistically significant differences were found. \u0000CONCLUSIONS: The developed method for calculating the estimated postoperative exophthalmos is effective without using additional software. This technique allows you to achieve a symmetrical eyeball position in the postoperative period and to reduce the risk of complications.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44359789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Pirogov, Fedor N. Rozhdestvenskiy, Polina A. Dzitstsoeva, A. Artiushenko
BACKGROUND: The prevalence of inflammatory complications that occur after phacoemulsification remains an unsolved problem. AIM: To analyze the results of the use of Ivinak-SOLOpharm eye drops containing 0.09% bromfenac solution in the complex of anti-inflammatory therapy in patients after cataract surgery in comparison with similar drugs from other manufacturers. MATERIALS AND METHODS: The study included 60 patients (60 eyes) with a diagnosis of age-related cataract, who underwent phacoemulsification. All patients were divided into 2 groups: in the first group, patients used Ivinac eye drops 3 days before surgery and 20 days after it; in the second group, patients used another similar drug containing 0.09% bromfenac solution according to an identical scheme. All patients underwent visual acuity testing and keratopachimetry before and after surgery. On Day 4 and Day 20 after surgery, the degree of inflammatory reaction of the eye was assessed by the number of cells in the anterior chamber fluid, subjective signs of inflammation in patients, using the OSDI (Ocular Surface Disease Index) questionnaire. RESULTS: When analyzing the obtained data, no statistically significant differences were found between the groups in terms of best corrected visual acuity, corneal thickness, number of cells in the anterior chamber fluid, and subjective symptoms of inflammation in patients. CONCLUSIONS: Ivinak-SOLOpharm has proven its effectiveness and safety in the perioperative prevention of inflammatory processes in phacoemulsification.
{"title":"Experience of the anti-inflammatory eye drops Ivinak®-solopharm use in patients after cataract surgery","authors":"I. Pirogov, Fedor N. Rozhdestvenskiy, Polina A. Dzitstsoeva, A. Artiushenko","doi":"10.17816/ov79196","DOIUrl":"https://doi.org/10.17816/ov79196","url":null,"abstract":"BACKGROUND: The prevalence of inflammatory complications that occur after phacoemulsification remains an unsolved problem. \u0000AIM: To analyze the results of the use of Ivinak-SOLOpharm eye drops containing 0.09% bromfenac solution in the complex of anti-inflammatory therapy in patients after cataract surgery in comparison with similar drugs from other manufacturers. \u0000MATERIALS AND METHODS: The study included 60 patients (60 eyes) with a diagnosis of age-related cataract, who underwent phacoemulsification. All patients were divided into 2 groups: in the first group, patients used Ivinac eye drops 3 days before surgery and 20 days after it; in the second group, patients used another similar drug containing 0.09% bromfenac solution according to an identical scheme. All patients underwent visual acuity testing and keratopachimetry before and after surgery. On Day 4 and Day 20 after surgery, the degree of inflammatory reaction of the eye was assessed by the number of cells in the anterior chamber fluid, subjective signs of inflammation in patients, using the OSDI (Ocular Surface Disease Index) questionnaire. \u0000RESULTS: When analyzing the obtained data, no statistically significant differences were found between the groups in terms of best corrected visual acuity, corneal thickness, number of cells in the anterior chamber fluid, and subjective symptoms of inflammation in patients. \u0000CONCLUSIONS: Ivinak-SOLOpharm has proven its effectiveness and safety in the perioperative prevention of inflammatory processes in phacoemulsification.","PeriodicalId":31539,"journal":{"name":"Ophthalmology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46895488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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