Pub Date : 2022-11-01Epub Date: 2022-10-24DOI: 10.1007/s00120-022-01957-7
Jens Rosellen, Thorsten Diemer, Arne Hauptmann, Florian Wagenlehner
Male hypogonadism is a congenital or acquired disorder that exerts a negative influence on various organ functions and can massively impair the quality of life through the relative or absolute deficiency of testosterone. A variety of preparations are available for substitution treatment, which differ in administration form and intake interval. For the execution of testosterone treatment various guidelines exist with clear and practical instructions on the indications, contraindications, treatment procedure and monitoring. Of particular importance are cardiovascular aspects and diseases of the prostate gland, which underlines the central position of the urologist in the treatment.
{"title":"[Testosterone treatment].","authors":"Jens Rosellen, Thorsten Diemer, Arne Hauptmann, Florian Wagenlehner","doi":"10.1007/s00120-022-01957-7","DOIUrl":"https://doi.org/10.1007/s00120-022-01957-7","url":null,"abstract":"<p><p>Male hypogonadism is a congenital or acquired disorder that exerts a negative influence on various organ functions and can massively impair the quality of life through the relative or absolute deficiency of testosterone. A variety of preparations are available for substitution treatment, which differ in administration form and intake interval. For the execution of testosterone treatment various guidelines exist with clear and practical instructions on the indications, contraindications, treatment procedure and monitoring. Of particular importance are cardiovascular aspects and diseases of the prostate gland, which underlines the central position of the urologist in the treatment.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1260-1275"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40569317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-01Epub Date: 2022-09-09DOI: 10.1007/s00120-022-01937-x
Kristin Dittrich, Uli Fischer, Bernadette Hosters, Andreas Kocks, Jennifer Luboeinski, Jana Luntz, Torsten Rantzsch, Regina Schmeer
{"title":"[Relevant to the system and innovative].","authors":"Kristin Dittrich, Uli Fischer, Bernadette Hosters, Andreas Kocks, Jennifer Luboeinski, Jana Luntz, Torsten Rantzsch, Regina Schmeer","doi":"10.1007/s00120-022-01937-x","DOIUrl":"https://doi.org/10.1007/s00120-022-01937-x","url":null,"abstract":"","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1256-1259"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33455867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-01Epub Date: 2022-10-11DOI: 10.1007/s00120-022-01952-y
Jennifer Kranz, Marco Hoffmann
{"title":"[Narrow Band Imaging versus white light cystoscopy alone in transurethral resection of non-muscle invasive bladder cancer : Study commentary].","authors":"Jennifer Kranz, Marco Hoffmann","doi":"10.1007/s00120-022-01952-y","DOIUrl":"https://doi.org/10.1007/s00120-022-01952-y","url":null,"abstract":"","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1249-1253"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33499676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-01Epub Date: 2022-11-04DOI: 10.1007/s00120-022-01944-y
B Wullich, K Golka
{"title":"[Urology and the environment].","authors":"B Wullich, K Golka","doi":"10.1007/s00120-022-01944-y","DOIUrl":"https://doi.org/10.1007/s00120-022-01944-y","url":null,"abstract":"","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1177-1178"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40680367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-01Epub Date: 2022-09-26DOI: 10.1007/s00120-022-01938-w
Klaus Golka, Ralf Böthig, Wobbeke Weistenhöfer, Olaf P Jungmann, Steffi Bergmann, Michael Zellner, Wolfgang Schöps
Occupation-related cancers are of considerable importance, which is not yet adequately recognized in the field of urology. The three numerically most significant entities are tumors of the urinary tract caused by carcinogenic aromatic amines or polycyclic aromatic hydrocarbons, renal cell cancer after high exposure to the solvent trichloroethylene, and mesotheliomas of the tunica vaginalis of the testis after exposure to asbestos; however, these can only be recognized as occupation-related if an occupational history regarding the hazard relevant to the organ bearing the tumor is documented from the beginning of employment, e.g. by a questionnaire. This is because the relevant exposures generally date back several decades. With the exception of high exposure to trichloroethylene, the substances mentioned can also environmentally trigger the same tumors. In the context of environmental risk factors, it is of considerable importance that smoking is now considered to be a trigger for some 50% of all bladder cancers in men and women; however, smoking cessation results in a reduction in smoking-related cancer risk of over 30% after only 3-4 years. Work and commuting accidents, which are considered occupational risks, can lead to urological sequelae. For example, increased tumors of the bladder can occur after spinal cord injury lasting longer than 10 years.
{"title":"[Occupation-related cancer in urology-Current knowledge including environmental medical aspects].","authors":"Klaus Golka, Ralf Böthig, Wobbeke Weistenhöfer, Olaf P Jungmann, Steffi Bergmann, Michael Zellner, Wolfgang Schöps","doi":"10.1007/s00120-022-01938-w","DOIUrl":"https://doi.org/10.1007/s00120-022-01938-w","url":null,"abstract":"<p><p>Occupation-related cancers are of considerable importance, which is not yet adequately recognized in the field of urology. The three numerically most significant entities are tumors of the urinary tract caused by carcinogenic aromatic amines or polycyclic aromatic hydrocarbons, renal cell cancer after high exposure to the solvent trichloroethylene, and mesotheliomas of the tunica vaginalis of the testis after exposure to asbestos; however, these can only be recognized as occupation-related if an occupational history regarding the hazard relevant to the organ bearing the tumor is documented from the beginning of employment, e.g. by a questionnaire. This is because the relevant exposures generally date back several decades. With the exception of high exposure to trichloroethylene, the substances mentioned can also environmentally trigger the same tumors. In the context of environmental risk factors, it is of considerable importance that smoking is now considered to be a trigger for some 50% of all bladder cancers in men and women; however, smoking cessation results in a reduction in smoking-related cancer risk of over 30% after only 3-4 years. Work and commuting accidents, which are considered occupational risks, can lead to urological sequelae. For example, increased tumors of the bladder can occur after spinal cord injury lasting longer than 10 years.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1198-1207"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33485862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-01Epub Date: 2022-10-13DOI: 10.1007/s00120-022-01951-z
Hans-Christian Schuppe, Frank-Michael Köhn
The identification of potential environmental hazards is of clinical relevance for the diagnosis of male infertility. Knowledge about these factors will improve prevention of fertility disorders. Apart from drugs or factors related to lifestyle such as alcohol and tobacco smoke, various environmental and occupational agents, both chemical and physical, may impair male reproduction. Reproductive toxicity may evolve at the hypothalamic-pituitary, testicular, or posttesticular level; endpoints comprise deterioration of spermatogenesis and sperm function as well as endocrine disorders and sexual dysfunction. However, due to the complex regulation of the male reproductive system, information regarding single exogenous factors and their mechanisms of action in humans is limited. This is also due to the fact that extrapolation of results obtained from experimental animal or in vitro studies remains difficult. Nevertheless, the assessment of relevant exposures to reproductive toxicants should be carefully evaluated during diagnostic procedures of andrological patients.
{"title":"[Impact of lifestyle and environmental factors on male reproductive health].","authors":"Hans-Christian Schuppe, Frank-Michael Köhn","doi":"10.1007/s00120-022-01951-z","DOIUrl":"https://doi.org/10.1007/s00120-022-01951-z","url":null,"abstract":"<p><p>The identification of potential environmental hazards is of clinical relevance for the diagnosis of male infertility. Knowledge about these factors will improve prevention of fertility disorders. Apart from drugs or factors related to lifestyle such as alcohol and tobacco smoke, various environmental and occupational agents, both chemical and physical, may impair male reproduction. Reproductive toxicity may evolve at the hypothalamic-pituitary, testicular, or posttesticular level; endpoints comprise deterioration of spermatogenesis and sperm function as well as endocrine disorders and sexual dysfunction. However, due to the complex regulation of the male reproductive system, information regarding single exogenous factors and their mechanisms of action in humans is limited. This is also due to the fact that extrapolation of results obtained from experimental animal or in vitro studies remains difficult. Nevertheless, the assessment of relevant exposures to reproductive toxicants should be carefully evaluated during diagnostic procedures of andrological patients.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1217-1228"},"PeriodicalIF":0.6,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33505465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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