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Intended and unintended consequences of the implementation of minimum unit pricing of alcohol in Scotland: a natural experiment 在苏格兰实施酒精最低单位定价的预期和意外后果:一个自然实验
Pub Date : 2021-10-01 DOI: 10.3310/phr09110
Vivian So, A. Millard, S. Katikireddi, Ross Forsyth, S. Allstaff, P. Deluca, C. Drummond, Allison Ford, D. Eadie, N. Fitzgerald, L. Graham, S. Hilton, A. Ludbrook, G. McCartney, O. Molaodi, Michele Open, C. Patterson, Samantha Perry, T. Phillips, G. Schembri, M. Stead, Janet Wilson, C. Yap, L. Bond, A. Leyland
Scotland was the first country to implement minimum unit pricing for alcohol nationally. Minimum unit pricing aims to reduce alcohol-related harms and to narrow health inequalities. Minimum unit pricing sets a minimum retail price based on alcohol content, targeting products preferentially consumed by high-risk drinkers. This study comprised three components. This study comprised three components assessing alcohol consumption and alcohol-related attendances in emergency departments, investigating potential unintended effects of minimum unit pricing on alcohol source and drug use, and exploring changes in public attitudes, experiences and norms towards minimum unit pricing and alcohol use. We conducted a natural experiment study using repeated cross-sectional surveys comparing Scotland (intervention) and North England (control) areas. This involved comparing changes in Scotland following the introduction of minimum unit pricing with changes seen in the north of England over the same period. Difference-in-difference analyses compared intervention and control areas. Focus groups with young people and heavy drinkers, and interviews with professional stakeholders before and after minimum unit pricing implementation in Scotland allowed exploration of attitudes, experiences and behaviours, stakeholder perceptions and potential mechanisms of effect. Four emergency departments in Scotland and North England (component 1), six sexual health clinics in Scotland and North England (component 2), and focus groups and interviews in Scotland (component 3). Research nurses interviewed 23,455 adults in emergency departments, and 15,218 participants self-completed questionnaires in sexual health clinics. We interviewed 30 stakeholders and 105 individuals participated in focus groups. Minimum unit pricing sets a minimum retail price based on alcohol content, targeting products preferentially consumed by high-risk drinkers. The odds ratio for an alcohol-related emergency department attendance following minimum unit pricing was 1.14 (95% confidence interval 0.90 to 1.44; p = 0.272). In absolute terms, we estimated that minimum unit pricing was associated with 258 more alcohol-related emergency department visits (95% confidence interval –191 to 707) across Scotland than would have been the case had minimum unit pricing not been implemented. The odds ratio for illicit drug consumption following minimum unit pricing was 1.04 (95% confidence interval 0.88 to 1.24; p = 0.612). Concerns about harms, including crime and the use of other sources of alcohol, were generally not realised. Stakeholders and the public generally did not perceive price increases or changed consumption. A lack of understanding of the policy may have caused concerns about harms to dependent drinkers among participants from more deprived areas. The short interval between policy announcement and implementation left limited time for pre-intervention dat
苏格兰是第一个在全国范围内实施酒精最低单位定价的国家。最低单位定价旨在减少与酒精有关的危害并缩小健康不平等。最低单位定价是根据酒精含量设定的最低零售价格,目标是高风险饮酒者优先消费的产品。本研究由三个部分组成。本研究包括三个组成部分,评估酒精消费和急诊部门与酒精相关的就诊率,调查最低单位定价对酒精来源和药物使用的潜在意外影响,并探索公众对最低单位定价和酒精使用的态度、经验和规范的变化。我们进行了一项自然实验研究,使用重复的横断面调查来比较苏格兰(干预)和北英格兰(对照)地区。这包括比较苏格兰引入最低单位定价后的变化与同期英格兰北部的变化。差异中差异分析比较了干预区和控制区。与年轻人和酗酒者的焦点小组,以及在苏格兰实施最低单位定价前后与专业利益相关者的访谈,允许探索态度,经验和行为,利益相关者的看法和潜在的影响机制。苏格兰和北英格兰的四个急诊科(组成部分1),苏格兰和北英格兰的六个性健康诊所(组成部分2),以及苏格兰的焦点小组和访谈(组成部分3)。研究护士在急诊科采访了23,455名成年人,在性健康诊所采访了15,218名参与者自行完成问卷。我们采访了30名利益相关者和105名参与焦点小组的个人。最低单位定价是根据酒精含量设定的最低零售价格,目标是高风险饮酒者优先消费的产品。最低单位定价后与酒精相关的急诊就诊的优势比为1.14(95%可信区间0.90 ~ 1.44;p = 0.272)。从绝对值来看,我们估计,在苏格兰,与没有实施最低单价相比,最低单价与酒精相关的急诊就诊增加了258次(95%置信区间-191至707)。最低单位定价后非法药物消费的优势比为1.04(95%可信区间为0.88 ~ 1.24;p = 0.612)。对危害的关切,包括犯罪和使用其他来源的酒精,一般没有实现。利益相关者和公众普遍没有察觉到价格上涨或消费改变。由于对这项政策缺乏了解,来自贫困地区的参与者可能会担心对依赖饮酒者的伤害。政策公布和实施之间的时间间隔很短,使得干预前数据收集的时间有限。在急诊部门,没有证据表明最低单位定价有有益的影响。执行工作似乎是成功的,没有证据表明有人用酒精代替其他药物。饮酒者和利益相关者大多表示没有注意到价格或消费量的任何变化。在这些环境中观察到的短期效果不足,以及没有问题的实施,表明每套产品的价格(0.5英镑)是可以接受的,但可能太低了。我们的评估本身包含多个组成部分,是苏格兰公共卫生协调的更广泛方案的一部分,结果应该在更广泛的背景下理解。对不同情况下价格不同的类似政策进行反复评价,可以更全面地了解价格与影响之间的关系。当前对照试验ISRCTN16039407。该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第9卷第11期请参阅NIHR期刊图书馆网站了解更多项目信息。
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引用次数: 8
An online family-based self-monitoring and goal-setting intervention to improve children’s physical activity: the FRESH feasibility trial and three-arm pilot RCT 基于家庭的在线自我监测和目标设定干预改善儿童体育活动:FRESH可行性试验和三组试点随机对照试验
Pub Date : 2021-09-01 DOI: 10.3310/phr09090
E. V. van Sluijs, H. Brown, E. Coombes, Claire Hughes, Andrew P. Jones, Katie L Morton, J. Guagliano
Family-based physical activity promotion presents a promising avenue for promoting whole-family physical activity, but high-quality research is lacking. To assess the feasibility, acceptability and preliminary effectiveness of FRESH (Families Reporting Every Step to Health), a child-led online family-based physical activity intervention; and to identify effective and resource-efficient family recruitment strategies. The project consisted of (1) a randomised feasibility trial, (2) a randomised controlled pilot trial and (3) a systematic review and Delphi study. Norfolk/Suffolk counties, UK. Families, recruited from schools, workplaces and community settings, were eligible to participate if one child aged 7–11 years and one adult responsible for their care provided written consent; all family members could participate. The FRESH intervention, guided by self-determination theory, targeted whole families and was delivered via an online platform. All family members received pedometers and were given website access to select family step challenges to ‘travel’ to target cities around the world, log steps, and track progress as they virtually globetrotted. Families were randomised to FRESH intervention, pedometer-only or control arm. Physical (e.g. blood pressure), psychosocial (e.g. family functioning) and behavioural (e.g. device-measured family physical activity) measures were collected at baseline and at 8- and 52-week follow-up. A mixed-methods process evaluation assessed the acceptability of the intervention and evaluation. Systematic search of four databases (Cochrane Library, PubMed, PsycINFO and SCOPUS). Articles were screened in duplicate, and data extraction was fully checked. Academic experts participated in the three-round Delphi study. Data were combined to identify effective and resource-efficient family recruitment strategies. Included generally healthy school-aged children and at least one adult; intervention attempted to change physical activity, sedentary behaviour, screen use, diet, or prevent overweight/obesity in multiple family members; presented relevant measure of effect in children and adults. The feasibility study (12 families, 32 participants; 100% retention at 8 weeks) demonstrated the feasibility and acceptability of FRESH, but highlighted that adaptations were required. Of 41 families recruited in the pilot study (149 participants), 98% and 88% were retained at the 8-week and 52-week follow-up, respectively. More children in the FRESH arm self-reported doing more family physical activity, and they thought that FRESH was fun. There were no notable between-group differences in children’s outcomes. Change in moderate to vigorous physical activity at 8 weeks favoured FRESH intervention adults [vs. control: 9.4 minutes/week (95% confidence interval 0.4 to 18.4) vs. pedometer only: 15.3 (95% confidence interval 6.0 to 24.5)], and was stronger in fathers, but th
以家庭为基础的体育活动促进为促进全家庭体育活动提供了一条很有前途的途径,但缺乏高质量的研究。评估FRESH(家庭向健康报告每一步)的可行性、可接受性和初步有效性,这是一项由儿童主导的在线家庭体育活动干预;以及确定有效和资源节约型的家庭招聘战略。该项目包括(1)随机可行性试验,(2)随机对照试验和(3)系统综述和德尔菲研究。英国诺福克郡/萨福克郡。从学校、工作场所和社区招募的家庭,如果一名7-11岁的儿童和一名负责照顾他们的成年人提供书面同意,则有资格参加;所有家庭成员都可以参加。FRESH的干预以自决理论为指导,针对整个家庭,并通过在线平台进行。所有家庭成员都收到了计步器,并可以访问网站,选择家庭步骤挑战,“旅行”到世界各地的目标城市,记录步骤,并在他们虚拟环球旅行时跟踪进度。家庭被随机分为FRESH干预组、仅计步器组或对照组。在基线以及8周和52周的随访中收集身体(如血压)、心理社会(如家庭功能)和行为(如设备测量的家庭体力活动)指标。混合方法过程评估评估了干预和评估的可接受性。系统检索四个数据库(Cochrane Library、PubMed、PsycINFO和SCOPUS)。对文章进行了一式两份的筛选,并对数据提取进行了全面检查。学术专家参与了三轮德尔菲研究。将数据结合起来,以确定有效和资源节约型的家庭招聘策略。包括一般健康的学龄儿童和至少一名成年人;干预措施试图改变多个家庭成员的体育活动、久坐行为、屏幕使用、饮食或预防超重/肥胖;介绍了在儿童和成人中的相关效果测量。可行性研究(12个家庭,32名参与者;8周时100%保留)证明了FRESH的可行性和可接受性,但强调需要适应。在试点研究中招募的41个家庭(149名参与者)中,分别有98%和88%在8周和52周的随访中被保留。在FRESH组中,更多的孩子自我报告做了更多的家庭体育活动,他们认为FRESH很有趣。儿童的结果在组间没有显著差异。8周时,中度至剧烈体力活动的变化有利于FRESH干预的成年人[与对照组相比:9.4分钟/周(95%置信区间0.4至18.4)与仅使用计步器相比:15.3(95%可信区间6.0至24.5)],父亲的体力活动更强,但这一点没有得到维持。在49项纳入的研究中,除了招募环境和使用的策略(分别有84%和73%的研究报告)外,招募细节很少。学校招聘占主导地位。德尔菲研究确定了广泛的招聘环境和策略。招聘是FRESH研究的主要局限性;拟议招聘策略的通用性可能有限。本研究证明了FRESH干预的可行性和可接受性。然而,我们未能招募到目标样本量,也无法证明有效性的信号。未来的研究应该采用多方面的招聘方法。应调查对提供干预和征聘方法的进一步改进。当前对照试验ISRCTN12789422和PROSPERO CRD42019140042。该项目由国家卫生研究所公共卫生研究计划资助,并将在《公共卫生研究》上全文发表;第9卷,第9期。有关更多项目信息,请访问NIHR期刊图书馆网站。
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引用次数: 3
School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis 以学校为基础的干预措施预防儿童和青少年的焦虑、抑郁和行为障碍:系统回顾和网络荟萃分析
Pub Date : 2021-07-01 DOI: 10.3310/phr09080
D. Caldwell, S. Davies, J. Thorn, J. Palmer, Paola Caro, S. Hetrick, D. Gunnell, Sumayya Anwer, J. López-López, C. French, J. Kidger, S. Dawson, R. Churchill, James Thomas, R. Campbell, N. Welton
Schools in the UK increasingly have to respond to anxiety, depression and conduct disorder as key causes of morbidity in children and young people. The objective was to assess the comparative effectiveness of educational setting-based interventions for the prevention of anxiety, depression and conduct disorder in children and young people. This study comprised a systematic review, a network meta-analysis and an economic evaluation. The databases MEDLINE, EMBASE™ (Elsevier, Amsterdam, the Netherlands), PsycInfo® (American Psychological Association, Washington, DC, USA) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched to 4 April 2018, and the NHS Economic Evaluation Database (NHS EED) was searched on 22 May 2019 for economic evaluations. No language or date filters were applied. The main outcomes were post-intervention self-reported anxiety, depression or conduct disorder symptoms. Randomised/quasi-randomised trials of universal or targeted interventions for the prevention of anxiety, depression or conduct disorder in children and young people aged 4–18 years were included. Screening was conducted independently by two reviewers. Data extraction was conducted by one reviewer and checked by a second. Intervention- and component-level network meta-analyses were conducted in OpenBUGS. A review of the economic literature and a cost–consequence analysis were conducted. A total of 142 studies were included in the review, and 109 contributed to the network meta-analysis. Of the 109 studies, 57 were rated as having an unclear risk of bias for random sequence generation and allocation concealment. Heterogeneity was moderate. In universal secondary school settings, mindfulness/relaxation interventions [standardised mean difference (SMD) –0.65, 95% credible interval (CrI) –1.14 to –0.19] and cognitive–behavioural interventions (SMD –0.15, 95% CrI –0.34 to 0.04) may be effective for anxiety. Cognitive–behavioural interventions incorporating a psychoeducation component may be effective (SMD –0.30, 95% CrI –0.59 to –0.01) at preventing anxiety immediately post intervention. There was evidence that exercise was effective in preventing anxiety in targeted secondary school settings (SMD –0.47, 95% CrI –0.86 to –0.09). There was weak evidence that cognitive–behavioural interventions may prevent anxiety in universal (SMD –0.07, 95% CrI –0.23 to 0.05) and targeted (SMD –0.38, 95% CrI –0.84 to 0.07) primary school settings. There was weak evidence that cognitive–behavioural (SMD –0.04, 95% CrI –0.16 to 0.07) and cognitive–behavioural + interpersonal therapy (SMD –0.18, 95% CrI –0.46 to 0.08) may be effective in preventing depression in universal secondary school settings. Third-wave (SMD –0.35, 95% CrI –0.70 to 0.00) and cognitive–behavioural interventions (SMD –0.11, 95% CrI –0.28 to 0.05) incorporating a psychoeducation component may be effective at preventing depression immediately post intervent
英国的学校越来越多地对焦虑、抑郁和行为障碍做出反应,这些都是儿童和年轻人发病的主要原因。目的是评估基于教育环境的干预措施在预防儿童和青少年的焦虑、抑郁和行为障碍方面的相对有效性。本研究包括系统综述、网络元分析和经济评价。检索数据库MEDLINE、EMBASE™(爱思唯尔,荷兰阿姆斯特丹)、PsycInfo®(美国心理学会,华盛顿特区,美国)和Cochrane中央对照试验注册库(Central)至2018年4月4日,并于2019年5月22日检索NHS经济评估数据库(NHS EED)进行经济评估。没有应用语言或日期过滤器。主要结果是干预后自我报告的焦虑、抑郁或行为障碍症状。纳入了4-18岁儿童和青少年预防焦虑、抑郁或行为障碍的普遍或有针对性干预措施的随机/准随机试验。筛选由两名评审人员独立进行。数据提取由一名审稿人进行,另一名审稿人进行检查。干预级和组件级网络元分析在OpenBUGS中进行。对经济学文献进行了回顾,并进行了成本-后果分析。本综述共纳入142项研究,其中109项用于网络荟萃分析。在109项研究中,57项被评为随机序列生成和分配隐藏的偏倚风险不明确。异质性为中等。在普遍的中学环境中,正念/放松干预[标准化平均差(SMD) -0.65, 95%可信区间(CrI) -1.14至-0.19]和认知行为干预(SMD -0.15, 95%可信区间(CrI) -0.34至0.04)可能对焦虑有效。包含心理教育成分的认知行为干预在干预后立即预防焦虑方面可能有效(SMD -0.30, 95% CrI -0.59至-0.01)。有证据表明,在目标中学环境中,运动可以有效预防焦虑(SMD -0.47, 95% CrI -0.86至-0.09)。有微弱的证据表明,认知行为干预可以在普遍(SMD -0.07, 95% CrI -0.23至0.05)和针对性(SMD -0.38, 95% CrI -0.84至0.07)小学环境中预防焦虑。有微弱的证据表明,认知行为疗法(SMD -0.04, 95% CrI -0.16至0.07)和认知行为+人际治疗(SMD -0.18, 95% CrI -0.46至0.08)可能在普遍的中学环境中有效预防抑郁症。第三波(SMD -0.35, 95% CrI -0.70至0.00)和认知行为干预(SMD -0.11, 95% CrI -0.28至0.05)结合心理教育成分可能在干预后立即有效预防抑郁症。干预后,没有证据表明在目标中学、目标小学或普遍小学环境中干预有效。由于网络元分析的不一致性,大学设置的结果不可靠。报告了五项行为障碍预防研究的叙述性总结,这些研究都是在小学环境中进行的。没有人报告干预后主要时间点的主要结局。经济证据综述报告了来自六项研究的异质性发现。从单一学校预算的角度来看,基于普遍中学环境中的认知行为疗法干预成本,成本-后果分析估计每位学生的干预成本为43英镑。强调针对特定障碍的预防排除了更广泛的心理健康干预措施,并限制了符合条件的行为障碍预防研究的数量。将研究限制在教育环境中提供的干预措施可能限制了合格的大学水平干预措施的数量。以学校为基础的、针对特定障碍的预防干预措施的有效性证据不足,尽管效果不大,证据也不充分。基于认知行为疗法的干预如果包括心理教育成分,可能会更有效。未来预防焦虑和抑郁的试验应该评估有或没有心理教育成分的认知行为干预,包括正念/放松或运动比较,并进行充分的随访。所涉成本必须得到充分衡量。本研究注册号为PROSPERO CRD42016048184。该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第9卷,第8号请参阅NIHR期刊图书馆网站了解更多项目信息。
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引用次数: 8
A school-based, peer-led programme to increase physical activity among 13- to 14-year-old adolescents: the GoActive cluster RCT 以学校为基础、以同伴为主导的增加13至14岁青少年身体活动的规划:GoActive集群随机对照试验
Pub Date : 2021-05-04 DOI: 10.3310/PHR09060
K. Corder, H. Brown, C. Croxson, Stephanie T Jong, S. Sharp, A. Vignoles, P. Wilkinson, Ed Wilson, E. V. van Sluijs
Adolescent physical activity levels are low and are associated with rising disease risk and social disadvantage. The Get Others Active (GoActive) intervention was co-designed with adolescents and teachers to increase physical activity in adolescents. To assess the effectiveness and cost-effectiveness of the school-based GoActive programme in increasing adolescents’ moderate-to-vigorous physical activity. A cluster randomised controlled trial with an embedded mixed-methods process evaluation. Non-fee-paying schools in Cambridgeshire and Essex, UK (n = 16). Schools were computer randomised and stratified by socioeconomic position and county. A total of 2862 Year 9 students (aged 13–14 years; 84% of eligible students). The iteratively developed feasibility-tested refined 12-week intervention trained older adolescents (mentors) and in-class peer leaders to encourage classes to undertake two new weekly activities. Mentors met with classes weekly. Students and classes gained points and rewards for activity in and out of school. The primary outcome was average daily minutes of accelerometer-assessed moderate-to-vigorous physical activity at 10 months post intervention. Secondary outcomes included accelerometer-assessed activity during school, after school and at weekends; self-reported physical activity and psychosocial outcomes; cost-effectiveness; well-being and a mixed-methods process evaluation. Measurement staff were blinded to allocation. Of 2862 recruited participants, 2167 (76%) attended 10-month follow-up measurements and we analysed the primary outcome for 1874 (65.5%) participants. At 10 months, there was a mean decrease in moderate-to-vigorous physical activity of 8.3 (standard deviation 19.3) minutes in control participants and 10.4 (standard deviation 22.7) minutes in intervention participants (baseline-adjusted difference –1.91 minutes, 95% confidence interval –5.53 to 1.70 minutes; p = 0.316). The programme cost £13 per student compared with control. Therefore, it was not cost-effective. Non-significant indications of differential impacts suggested detrimental effects among boys (boys –3.44, 95% confidence interval –7.42 to 0.54; girls –0.20, 95% confidence interval –3.56 to 3.16), but favoured adolescents from lower socioeconomic backgrounds (medium/low 4.25, 95% confidence interval –0.66 to 9.16; high –2.72, 95% confidence interval –6.33 to 0.89). Mediation analysis did not support the use of any included intervention components to increase physical activity. Some may have potential for improving well-being. Students, teachers and mentors mostly reported enjoying the GoActive intervention (56%, 87% and 50%, respectively), but struggled to conceptualise their roles. Facilitators of implementation included school support, embedding a routine, and mentor and tutor support. Challenges to implementation included having limited school space for activities, time, and uncertainty of teacher
青少年身体活动水平低,与疾病风险上升和社会不利地位有关。让他人积极活动(GoActive)干预与青少年和教师共同设计,以增加青少年的身体活动。评估以学校为基础的GoActive项目在增加青少年中高强度身体活动方面的有效性和成本效益。一项嵌入混合方法工艺评价的整群随机对照试验。英国剑桥郡和埃塞克斯的免费学校(n = 16)。学校是计算机随机化的,并根据社会经济地位和县进行分层。共2862名九年级学生(13-14岁;84%的合格学生)。经过反复开发和可行性测试的精细化的12周干预训练了年龄较大的青少年(导师)和班级同伴领导,以鼓励班级开展两项新的每周活动。导师们每周都来上课。学生和班级在学校内外的活动都获得了分数和奖励。主要结果是干预后10个月,加速度计评估的中等到剧烈身体活动的平均每日分钟数。次要结果包括在学校、放学后和周末进行加速度计评估的活动;自我报告的身体活动和社会心理结果;成本效益;幸福和混合方法过程评价。测量人员对分配不知情。在招募的2862名参与者中,2167名(76%)参加了10个月的随访测量,我们分析了1874名(65.5%)参与者的主要结局。在10个月时,对照组中至高强度体力活动平均减少8.3分钟(标准差19.3),干预组平均减少10.4分钟(标准差22.7)(基线调整差-1.91分钟,95%置信区间-5.53至1.70分钟);p = 0.316)。与对照组相比,该项目的成本为每位学生13英镑。因此,这是不划算的。差异影响的非显著迹象表明男孩的有害影响(男孩-3.44,95%置信区间-7.42至0.54;女孩-0.20,95%可信区间-3.56至3.16),但偏爱来自较低社会经济背景的青少年(中/低4.25,95%可信区间-0.66至9.16;高点-2.72,95%置信区间-6.33至0.89)。中介分析不支持使用任何包含的干预成分来增加身体活动。其中一些可能有改善幸福感的潜力。学生、教师和导师大多表示喜欢GoActive干预(分别为56%、87%和50%),但难以概念化他们的角色。实施的推动者包括学校支持、嵌入例行程序以及导师和导师支持。实施的挑战包括有限的学校活动空间、时间以及教师和导师角色的不确定性。在10个月的随访中,主要结局的保留率很低(65.5%),但我们达到了预期的样本量,保留率与类似试验相当。严格制定的以学校为基础的干预措施(即GoActive)在应对与年龄相关的青少年体育活动减少方面并不有效。总的来说,这种混合方法的评估为未来干预措施的制定、实施和评估提供了可转移的见解。需要跨学科的研究来了解教育环境特定的实施挑战。学校领导和当局应该对大规模实施以学校为基础的体育活动促进战略的效果抱有现实的期望。当前对照试验ISRCTN31583496。该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第9卷第6期请参阅NIHR期刊图书馆网站了解更多项目信息。这项工作还得到了医学研究理事会(英国伦敦)的额外支持(项目编号MC_UU_12015/7),并在饮食和活动研究中心(英国剑桥)的主持下进行,该中心是英国临床研究合作公共卫生卓越研究中心。感谢英国心脏基金会(英国伦敦)、英国癌症研究所(英国伦敦)、经济和社会研究理事会(英国斯文顿)、医学研究理事会、国家卫生研究所(英国南安普顿)和威康信托基金会(英国伦敦)在英国临床研究合作组织的主持下提供的资金(087636/Z/08/Z;ES / G007462/1;先生/ K023187/1)。GoActive促进者的费用由埃塞克斯郡和剑桥郡议会承担。
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引用次数: 7
A digital behaviour change intervention to increase booking and attendance at Stop Smoking Services: the MyWay feasibility RCT 数字行为改变干预以增加戒烟服务的预约和出席:MyWay可行性随机对照试验
Pub Date : 2021-04-13 DOI: 10.3310/PHR09050
E. Fulton, K. Newby, K. Kwah, Lauren Schumacher, K. Gokal, Louise J Jackson, F. Naughton, T. Coleman, A. Owen, K. Brown
Background Smoking remains a leading cause of illness and preventable death. NHS Stop Smoking Services increase quitting, but, as access is in decline, cost-effective interventions are needed that promote these services. StopApp™ (Coventry University, Coventry, UK) is designed to increase booking and attendance at Stop Smoking Services. Design A two-arm feasibility randomised controlled trial of StopApp (intervention) compared with standard promotion and referral to Stop Smoking Services (control) was conducted to assess recruitment, attrition and health equity of the design, alongside health economic and qualitative process evaluations. Setting Smokers recruited via general practitioners, community settings and social media. Participants Smokers aged ≥ 16 years were recruited in one local authority. Participants had to live or work within the local authority area, and there was a recruitment target of 120 participants. Interventions StopApp to increase booking and attendance at Stop Smoking Services. Main outcome measures Participants completed baseline measures and follow-up at 2 months post randomisation entirely online. Objective data on the use of Stop Smoking Services were collected from participating Stop Smoking Services, and age groups, sex, ethnicity and socioeconomic status in baseline recruits and follow-up completers/non-completers were assessed for equity. Results Eligible participants (n = 123) were recruited over 116 days, with good representation of lower socioeconomic status groups; black, Asian and minority ethnic groups; and all age groups. Demographic profiles of follow-up completers and non-completers were broadly similar. The attrition rate was 51.2%, with loss to follow-up lowest in the social media setting (n = 24/61; 39.3%) and highest in the general practitioner setting (n = 21/26; 80.8%). Most measures had Conclusion This feasibility randomised controlled trial found that, with recruitment driven wholly or mainly by social media, it is possible to recruit and retain sufficient smokers to assess the effectiveness and cost-effectiveness of StopApp. The study methods and measures were found to be acceptable and equitable, but accessing Stop Smoking Services data about booking, attendance and quit dates was a challenge. A full trial may be feasible if service data are accessible. This will require careful planning with data controllers and a targeted social media campaign for recruitment. Changes to some study measures are needed to avoid missing data, including implementation of a more intensive follow-up data collection process. Future work We plan a full, definitive randomised controlled trial if the concerns around data access can be resolved, with adaptations to the recruitment and retention strategy. Limitations Our trial had high attrition and problems with collecting Stop Smoking Services data, which resulted in a reliance on self-reporting. Trial registration Research Registry: 3995. The trial was registered on 18
吸烟仍然是导致疾病和可预防死亡的主要原因。国民保健制度戒烟服务增加了戒烟,但由于获得机会减少,需要采取具有成本效益的干预措施来促进这些服务。StopApp™(考文垂大学,考文垂,英国)旨在增加戒烟服务的预订和出席率。设计进行了一项双组可行性随机对照试验,将戒烟应用(干预)与标准推广和转介戒烟服务(对照)进行比较,以评估设计的招募、减员和健康公平性,以及健康经济和定性过程评估。通过全科医生、社区环境和社交媒体招募的吸烟者。参与者在一个地方当局招募年龄≥16岁的吸烟者。参与者必须在当地政府管辖范围内生活或工作,招募目标为120名参与者。干预措施停止应用程序增加预约和出席戒烟服务。参与者在随机化后2个月完全在线完成基线测量和随访。从参与戒烟服务的人中收集有关戒烟服务使用的客观数据,并对基线新兵和随访完成者/未完成者的年龄、性别、种族和社会经济地位进行公平性评估。结果符合条件的参与者(n = 123)在116天内被招募,具有较低社会经济地位群体的良好代表性;黑人、亚洲人和少数民族;以及所有年龄段的人。随访完成者和非完成者的人口学特征大致相似。流失率为51.2%,在社交媒体环境中流失率最低(n = 24/61;39.3%),全科医生组最高(n = 21/26;80.8%)。这项可行性随机对照试验发现,通过完全或主要由社交媒体驱动的招募,有可能招募并留住足够的吸烟者来评估StopApp的有效性和成本效益。研究方法和措施被认为是可以接受和公平的,但获取戒烟服务机构关于预约、出勤和戒烟日期的数据是一个挑战。如果服务数据是可访问的,完整的试验可能是可行的。这将需要与数据控制者一起仔细规划,并进行有针对性的社交媒体招聘活动。需要改变一些研究措施以避免丢失数据,包括实施更密集的后续数据收集过程。如果能够解决有关数据访问的问题,我们计划进行一次完整的、明确的随机对照试验,并适应招聘和保留策略。我们的试验在收集戒烟服务数据方面存在高流失率和问题,这导致了对自我报告的依赖。试验注册研究注册:3995。该试验于2018年4月18日登记。该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第九卷,第五期请参阅NIHR期刊图书馆网站了解更多项目信息。
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引用次数: 0
Potential effects of minimum unit pricing at local authority level on alcohol-attributed harms in North West and North East England: a modelling study 英格兰西北部和东北部地方当局最低单位定价对酒精危害的潜在影响:一项模型研究
Pub Date : 2021-03-23 DOI: 10.3310/PHR09040
A. Brennan, C. Angus, R. Pryce, Penny Buykx, Madeleine Henney, D. Gillespie, J. Holmes, P. Meier
In 2018, Scotland implemented a 50p-per-unit minimum unit price for alcohol. Previous modelling estimated the impact of minimum unit pricing for England, Scotland, Wales and Northern Ireland. Decision-makers want to know the potential effects of minimum unit pricing for local authorities in England; the premise of this study is that estimated effects of minimum unit pricing would vary by locality. The objective was to estimate the potential effects on mortality, hospitalisations and crime of the implementation of minimum unit pricing for alcohol at local authority level in England. This was an evidence synthesis, and used computer modelling using the Sheffield Alcohol Policy Model (local authority version 4.0). This study gathered evidence on local consumption of alcohol from the Health Survey for England, and gathered data on local prices paid from the Living Costs and Food Survey and from market research companies’ actual sales data. These data were linked with local harms in terms of both alcohol-attributable mortality (from the Office for National Statistics) and alcohol-attributable hospitalisations (from Hospital Episode Statistics) for 45 conditions defined by the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision. These data were examined for eight age–sex groups split by five Index of Multiple Deprivation quintiles. Alcohol-attributable crime data (Office for National Statistics police-recorded crimes and uplifts for unrecorded offences) were also analysed. This study was set in 23 upper-tier local authorities in North West England, 12 upper-tier local authorities in the North East region and nine government office regions, and a national summary was conducted. The participants were the population of England aged ≥ 18 years. The intervention was setting a local minimum unit price. The base case is 50p per unit of alcohol. Sensitivity analyses were undertaken using minimum unit prices of 30p, 40p, 60p and 70p per unit of alcohol. The main outcome measures were changes in alcohol-attributable deaths, hospitalisations and crime. Savings in NHS costs, changes in alcohol purchasing and consumption, changes in revenue to off-trade and on-trade retailers and changes in the slope index of inequality between most and least deprived areas were also examined. The modelling has proved feasible at the upper-tier local authority level. The resulting estimates suggest that minimum unit pricing for alcohol at local authority level could be effective in reducing alcohol-attributable deaths, hospitalisations, NHS costs and crime. A 50p minimum unit price for alcohol at local authority level is estimated to reduce annual alcohol-related deaths in the North West region by 205, hospitalisations by 5956 (–5.5%) and crimes by 8528 (–2.5%). These estimated reductions are mostly due to the 5% of people drinking at high-risk levels (e.g. men drinking > 25 pints of b
2018年,苏格兰对酒类实行了每单位50便士的最低单价。先前的模型估计了最低单价对英格兰、苏格兰、威尔士和北爱尔兰的影响。决策者想知道最低单位定价对英国地方政府的潜在影响;本研究的前提是最低单位定价的估计效果会因地而异。目的是估计在英格兰地方当局一级实施酒精最低单位定价对死亡率、住院率和犯罪率的潜在影响。这是一个证据综合,并使用谢菲尔德酒精政策模型(地方当局版本4.0)的计算机建模。这项研究从英国健康调查中收集了当地酒精消费的证据,从生活成本和食品调查中收集了当地价格的数据,并从市场研究公司的实际销售数据中收集了数据。根据《国际疾病和相关健康问题统计分类第十版》所定义的45种疾病,这些数据与当地危害有关,包括酒精导致的死亡率(来自国家统计局)和酒精导致的住院率(来自医院事件统计)。这些数据是根据多重剥夺指数五分位数划分的八个年龄-性别组进行的。还分析了与酒精有关的犯罪数据(国家统计局警察记录的犯罪和未记录犯罪的上升)。本研究设置在英格兰西北部的23个上层地方当局,东北部地区的12个上层地方当局和9个政府办公区,并进行了全国性的总结。研究对象为年龄≥18岁的英格兰人口。干预措施是设定当地最低单价。基准情况是每单位酒精50便士。采用每单位酒精最低单价30p、40p、60p和70p进行敏感性分析。主要结果测量是酒精导致的死亡、住院和犯罪的变化。还审查了国民保健服务费用的节省、酒精购买和消费的变化、贸易外和贸易内零售商收入的变化以及最贫困地区和最不贫困地区之间不平等的斜率指数的变化。该模型在上层地方政府层面已被证明是可行的。由此产生的估计表明,在地方当局一级对酒精实行最低单位定价可以有效地减少酒精导致的死亡、住院、国民保健服务费用和犯罪。据估计,在地方当局一级,酒精最低单价为50便士,将使西北地区每年与酒精有关的死亡人数减少205人,住院人数减少5956人(-5.5%),犯罪人数减少8528人(-2.5%)。这些估计的减少主要是由于5%的人饮酒处于高风险水平(例如,男性每周喝25品脱啤酒或5瓶葡萄酒,女性每周喝17品脱啤酒或3.5瓶葡萄酒,目前每年在酒精上的花费约为2500英镑)。对西北和东北地区影响的模型估计比全国范围更大,因为目前这些地区消费的廉价酒精更多,而且这些地区与酒精有关的死亡和住院人数更多。最低单价为30p的估计效果比最低单价为50p的估计效果低约90%,最低单价为40p的估计效果低约50%。据估计,在贫困地区,健康不平等现象减少,健康收益更大,因为那里购买的廉价酒精更多,基线危害也更高。这种方法需要综合来自多个来源的关于酒精消费的证据;价格;疾病发病率,死亡率和犯罪率。所使用的价格弹性来自英国以前对价格响应性的分析,而不是特定于当地地区。这项研究没有估计“跨境效应”,即前往该地区以外的商店购物。模型估计表明,地方当局一级的最低酒精单位定价将是一项有效和目标明确的政策,可以减少不平等现象。可以进一步利用谢菲尔德地方当局酒精政策模型框架来审查国家政策(例如税收变化)或地方政策(例如许可或鉴定和简要咨询)对地方的影响。随着苏格兰最低单价实施的证据出现,这将进一步为英格兰地方的影响估计提供信息。用于估计每个地方当局的饮酒和购买模式的方法也可用于涉及影响公共健康的不健康产品的其他专题,例如,估计当地吸烟或高脂肪、高盐食品的消费模式。 该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第9卷,第4号请参阅NIHR期刊图书馆网站了解更多项目信息。
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引用次数: 4
Slip-resistant footwear to reduce slips among health-care workers: the SSHeW RCT 减少卫生保健工作者滑倒的防滑鞋:sshow随机对照试验
Pub Date : 2021-02-01 DOI: 10.3310/PHR09030
S. Cockayne, C. Fairhurst, Michael Zand, G. Frost, M. Liddle, Rachel Cunningham-Burley, C. Hewitt, H. Iles-Smith, L. Green, Emily Bain, Misbah Mogradia, D. Torgerson
In Great Britain, 100,000 injuries due to slips, trips and falls on the level (as opposed to falls from a height, e.g. a ladder) occur in the workplace each year. They are the most common cause of non-fatal injury in the workplace, accounting for 30% of all those injuries reported to the Health and Safety Executive. Nearly 1 million working days are lost because of slips, trips and falls each year. To assess the clinical effectiveness and cost-effectiveness of 5-star, GRIP-rated, slip-resistant footwear in preventing slips in the workplace compared with usual footwear. A two-arm, multicentre, randomised controlled trial with an economic evaluation and qualitative study. Seven NHS trusts in England. NHS staff aged ≥ 18 years, working at least 22.5 hours per week in clinical, general or catering areas who owned a mobile phone. Staff required to wear protective footwear were excluded. Intervention participants were offered 5-star, GRIP-rated, slip-resistant footwear. The waiting list control group were asked to wear their usual work shoes for the duration of the study and were offered the trial footwear at the end of their participation. The primary outcome was the incidence rate of self-reported slips in the workplace over 14 weeks. Secondary outcomes included the incidence rate of falls either resulting from a slip or not resulting from a slip, proportion of participants reporting a slip, fall or fracture, time to first slip and fall, health-related quality of life and cost-effectiveness. A total of 4553 eligible NHS staff were randomised (2275 to the intervention arm and 2278 to the control arm). In total, 6743 slips were reported [2633 in the intervention group (mean 1.16 per participant, range 0–36 per participant) and 4110 in the control group (mean 1.80 per participant, range 0–83 per participant)]. There was a statistically significant reduction in the slip rate in the intervention group relative to the control group (incidence rate ratio 0.63, 95% confidence interval 0.57 to 0.70; p < 0.001). Statistically significant reductions were observed in falls from a slip (incidence rate ratio 0.51, 95% confidence interval 0.28 to 0.92; p = 0.03), the proportion of participants who reported a slip (odds ratio 0.58, 95% confidence interval 0.50 to 0.66; p < 0.001) or fall (odds ratio 0.73, 95% confidence interval 0.54 to 0.99; p = 0.04) and the time to first slip (hazard ratio 0.73, 95% confidence interval 0.67 to 0.80; p < 0.001). Half of the intervention participants wore the shoes all the time at work. Incremental cost per quality-adjusted life-year in the base case was £38,900 from the NHS perspective and –£60,400 (i.e. cost saving) from the societal perspective. This was an unblinded trial in which outcome data were participant self-reported, which may have led to inaccuracies in the reported slip data. Exposure to the trial footwear was lower than hoped. The offer and provision
在英国,每年有10万人在工作场所因滑倒、绊倒和摔倒(而不是从高处坠落,如梯子)而受伤。它们是工作场所非致命伤害的最常见原因,占向健康与安全执行局报告的所有伤害的30%。每年有近100万个工作日因滑倒、绊倒和跌倒而损失。与普通鞋类相比,评估五星级GRIP级防滑鞋在预防工作场所滑倒方面的临床有效性和成本效益。一项具有经济评估和定性研究的双臂、多中心、随机对照试验。英国的七个NHS信托基金。NHS工作人员年龄≥ 18岁,每周至少在临床、普通或餐饮领域工作22.5小时,拥有手机。要求穿防护鞋的工作人员被排除在外。干预参与者被提供了五星级、GRIP评级的防滑鞋。等待名单对照组被要求在研究期间穿上他们通常的工作鞋,并在参与结束时获得试验鞋。主要结果是14周内工作场所自我报告失误的发生率。次要结果包括由滑倒或非滑倒引起的跌倒发生率、报告滑倒、跌倒或骨折的参与者比例、首次滑倒和跌倒的时间、与健康相关的生活质量和成本效益。共有4553名符合条件的NHS工作人员被随机分配(2275人分配给干预组,2278人分配给对照组)。总共报告了6743次失误【干预组2633次(平均每位参与者1.16次,范围0-36次),对照组4110次(平均每场参与者1.80次,幅度0-83次)】。与对照组相比,干预组的滑动率在统计学上显著降低(发病率比0.63,95%置信区间0.57至0.70;p < 0.001)。从统计学上观察到从滑倒中跌倒的人数显著减少(发病率比0.51,95%置信区间0.28-0.92;p = 0.03),报告失误的参与者比例(比值比0.58,95%置信区间0.50至0.66;p < 0.001)或跌倒(比值比0.73,95%置信区间0.54至0.99;p = 0.04)和第一次滑动的时间(风险比0.73,95%置信区间0.67至0.80;p < 0.001)。一半的干预参与者在工作时一直穿着这双鞋。从NHS的角度来看,基本情况下每个质量调整生命年的增量成本为38900英镑,从社会的角度来看为60400英镑(即成本节约)。这是一项非盲试验,结果数据是参与者自我报告的,这可能导致报告的滑动数据不准确。试验鞋的暴露量低于预期。提供和提供五星级GRIP级鞋类减少了工作场所的打滑,参与者可以接受,并且具有成本效益。可能需要在其他环境中复制该研究,以评估在其他环境(如餐饮和工厂)中的临床有效性和成本效益。当前对照试验ISRCTN33051393。该项目由国家卫生研究所公共卫生研究计划资助,并将在《公共卫生研究》上全文发表;第9卷第3期。有关更多项目信息,请访问美国国立卫生研究院公共期刊图书馆网站。健康与安全执行局提供了一些研究费用。
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引用次数: 1
Exploring the uptake and use of electronic cigarettes provided to smokers accessing homeless centres: a four-centre cluster feasibility trial 探索向进入无家可归中心的吸烟者提供电子烟的吸收和使用:一项四中心集群可行性试验
Pub Date : 2021-01-21 DOI: 10.3310/PHR09070
S. Cox, Allison Ford, Jinshuo Li, C. Best, Allan Tyler, D. Robson, L. Bauld, P. Hajek, I. Uny, S. Parrott, L. Dawkins
Background Smoking prevalence is extremely high in adults experiencing homelessness, and there is little evidence regarding which cessation interventions work best. This study explored the feasibility of providing free electronic cigarette starter kits to smokers accessing homeless centres in the UK. Objectives Seven key objectives were examined to inform a future trial: (1) assess willingness of smokers to participate in the study to estimate recruitment rates; (2) assess participant retention in the intervention and control arms; (3) examine the perceived value of the intervention, facilitators of and barriers to engagement, and influence of local context; (4) assess service providers’ capacity to support the study and the type of information and training required; (5) assess the potential efficacy of supplying free electronic cigarette starter kits; (6) explore the feasibility of collecting data on contacts with health-care services as an input to a main economic evaluation; and (7) estimate the cost of providing the intervention and usual care. Design A prospective cohort four-centre pragmatic cluster feasibility study with embedded qualitative process evaluation. Setting Four homeless centres. Two residential units in London, England. One day centre in Northampton, England. One day centre in Edinburgh, Scotland. Intervention In the intervention arm, a single refillable electronic cigarette was provided together with e-liquid, which was provided once per week for 4 weeks (choice of three flavours: fruit, menthol or tobacco; two nicotine strengths: 12 or 18 mg/ml). There was written information on electronic cigarette use and support. In the usual-care arm, written information on quitting smoking (adapted from NHS Choices) and signposting to the local stop smoking service were provided. Results Fifty-two per cent of eligible participants invited to take part in the study were successfully recruited (56% in the electronic cigarette arm; 50.5% in the usual-care arm; total n = 80). Retention rates were 75%, 63% and 59% at 4, 12 and 24 weeks, respectively. The qualitative component found that perceived value of the intervention was high. Barriers were participants’ personal difficulties and cannabis use. Facilitators were participants’ desire to change, free electronic cigarettes and social dynamics. Staff capacity to support the study was generally good. Carbon monoxide-validated sustained abstinence rates at 24 weeks were 6.25% (3/48) in the electronic cigarette arm compared with 0% (0/32) in the usual-care arm (intention to treat). Almost all participants present at follow-up visits completed measures needed for input into an economic evaluation, although information about staff time to support usual care could not be gathered. The cost of providing the electronic cigarette intervention was estimated at £114.42 per person. An estimated cost could not be calculated for usual care. Limitations Clusters could not be fully randomised because of a l
背景:在无家可归的成年人中,吸烟率极高,而且几乎没有证据表明哪种戒烟干预措施效果最好。本研究探讨了向英国无家可归者中心的吸烟者提供免费电子烟入门包的可行性。研究了七个关键目标,为未来的试验提供信息:(1)评估吸烟者参与研究的意愿,以估计招募率;(2)评估干预组和控制组参与者的保留率;(3)检查干预的感知价值、参与的促进因素和障碍,以及当地环境的影响;(4)评估服务提供商支持研究的能力以及所需的信息和培训类型;(5)评估免费提供电子烟入门包的潜在功效;(6)探讨收集与保健服务接触的数据作为主要经济评价的投入的可行性;(7)评估提供干预和日常护理的成本。设计一项采用嵌入定性过程评价的前瞻性队列四中心语用集群可行性研究。四个无家可归者中心。位于英国伦敦的两个住宅单元。英国北安普顿的日间中心。苏格兰爱丁堡的日托中心。在干预组中,提供一支可重新填充的电子烟和电子烟液,每周提供一次,持续4周(三种口味的选择:水果、薄荷或烟草;两种尼古丁浓度:12或18毫克/毫升)。有关于电子烟使用和支持的书面信息。在日常护理组,提供了关于戒烟的书面信息(改编自NHS的选择)和当地戒烟服务的路标。被邀请参加研究的合格参与者中有52%被成功招募(56%在电子烟组;日常护理组为50.5%;总n = 80)。4周、12周和24周的保留率分别为75%、63%和59%。定性成分发现干预的感知价值高。障碍是参与者的个人困难和大麻的使用。促进因素是参与者改变的愿望、免费电子烟和社会动态。工作人员支持这项研究的能力总体上是好的。电子烟组经一氧化碳验证的24周持续戒断率为6.25%(3/48),而常规护理组(有意治疗)为0%(0/32)。参加后续访问的几乎所有参与者都完成了为经济评价投入所需的措施,尽管无法收集到有关工作人员支助日常护理的时间的资料。提供电子烟干预的成本估计为每人114.42英镑。无法计算常规护理的估计费用。由于缺乏中心准备,群集不能完全随机化。原先规定的征聘目标没有达到,在寄宿中心征聘特别困难。不可能采用盲法来测量结果。工作人员支持日常护理的时间无法收集。结论:该研究与合理的招募率和保留率以及在电子烟领域有希望的可接受性有关。可以收集电子烟组进行全面成本效益评估所需的数据,但在常规护理组中无法获得一些数据。未来的工作未来的研究应该集中在几个关键问题上,以帮助设计针对这一人群的最佳研究和干预措施,包括干预措施在哪种类型的中心效果最好,如何最好地留住研究参与者,如何帮助工作人员提供干预措施,以及如何最好地记录工作人员的治疗时间。当前对照试验ISRCTN14140672;该协议注册为researchregistry4346。该项目由国家卫生研究所(NIHR)公共卫生研究方案资助,将全文发表在《公共卫生研究》上;第九卷,第七期请参阅NIHR期刊图书馆网站了解更多项目信息。
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引用次数: 5
Activation of Hospice & Palliative Care Education Program for the Volunteers 为义工启动安宁疗护及缓和疗护教育计划
Pub Date : 2021-01-01 DOI: 10.22900/KPHR.2021.47.1.002
C. hyun, Byung-Jun Cho, Seoyoung Cho, Seul Min Cho, S. Jeong
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引用次数: 0
Association between Age at Natural Menopause and Prevalence of Obesity, Hypertension, Diabetes, and Hypercholesterolemia 自然绝经年龄与肥胖、高血压、糖尿病和高胆固醇血症患病率之间的关系
Pub Date : 2021-01-01 DOI: 10.22900/KPHR.2021.47.1.001
S. Kim, Sangshin Park
{"title":"Association between Age at Natural Menopause and Prevalence of Obesity, Hypertension, Diabetes, and Hypercholesterolemia","authors":"S. Kim, Sangshin Park","doi":"10.22900/KPHR.2021.47.1.001","DOIUrl":"https://doi.org/10.22900/KPHR.2021.47.1.001","url":null,"abstract":"","PeriodicalId":32306,"journal":{"name":"Public Health Research","volume":"47 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68345210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
期刊
Public Health Research
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