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Stenting of ultraembolic hazardous carotid stenotic lesions using the technique of triple antiembolic protection 应用三重抗栓塞保护技术治疗超栓塞性危险颈动脉狭窄病变
Pub Date : 2021-11-20 DOI: 10.26683/2786-4855-2021-2(36)-14-24
Y. Cherednichenko, M. Zorin, A.Yu Miroshnichenko, N. Cherednichenko
Objective ‒ to develop a technique of triple antiembolic protection with the simultaneous use of proximal antiembolic protection systems, distal antiembolic filters and two-layer micromesh carotid stents for carotid stenting of ultraembolic hazardous carotid stenosis. Evaluate its effectiveness and safety.Materials and methods. Since 2016, 23 carotid stenting of ultraembolic hazardous carotid stenoses has been performed using the technique of triple antiembolic protection (proximal antiembolic protection systems, distal antiembolic filters and two-layer micromesh carotid stents). All patients had symptomic stenosis: transient ischemic attacks in a certain carotid pool (n = 7), ischemic strokes (n = 16). The age of patients was from 57 to 84 years. Men prevailed among patients (n = 15). Postoperative follow-up included magnetic resonance imaging (MRI) of the brain on the first or second day after surgery with T2*, FLAIR and DWI sequences to determine the presence of «fresh» embolic ischemic foci and to exclude hemorrhagic complications. After 6 months, a control clinical examination, computed tomography or MRI of the brain, ultrasound angioscanning of the main arteries of the head were performed.Results. In all patients the patency of the carotid arteries was completely restored, and in the early postoperative period, no clinical signs of recurrent ischemic brain damage were detected in any of the cases. No signs of plaque prolapse through the stent were detected in any case. A significant amount of atheromatous debris was in 11 cases when aspirated on an external filter. In 3 cases, emboli were also detected in the distal protection filter. This fact indicates that the joint use of distal and proximal antiembolic systems reliably protects against the risk of embolism in such cases. According to MRI on the 1st or 2nd day there were no signs of «fresh» subclinical embolic ischemic foci, as well as hemorrhage. In 20 patients who underwent a follow-up examination, no signs of restenosis in the stent were recorded in any case, as well as repeated ischemic strokes. In 7 cases where the plaque had an ulcer, the ulcer resolved under the stent. Three patients are expected for a follow-up examination. According to the remote survey, these patients do not have new ischemic brain lesions. The effectiveness of the technique of triple antiembolic protection for the treatment of patients with subtotal ultraembolic hazardous carotid stenosis is indicated by the absence of clinical and neuroradiological signs of recurrent ischemic lesions.Conclusions. The technique of triple antiembolic protection for the treatment of patients with subtotal ultraembolic hazardous carotid stenoses is safe and highly effective. It is the improvement of carotid stenting results in this most dangerous group that gives reason to think about revealing the advantages of carotid stenting over carotid endarterectomy in general.
目的:建立一种同时使用近端抗栓塞保护系统、远端抗栓塞过滤器和双层微孔颈动脉支架的三重抗栓塞保护技术,用于超栓塞性危险颈动脉狭窄的颈动脉支架置入术。评估其有效性和安全性。材料和方法。自2016年以来,采用三重抗栓塞保护技术(近端抗栓塞保护系统、远端抗栓塞过滤器和双层微孔颈动脉支架)完成了23例超栓塞性危险颈动脉狭窄的颈动脉支架植入术。所有患者均有症状性狭窄:某颈动脉池短暂性缺血性发作(n = 7),缺血性卒中(n = 16)。患者年龄57 ~ 84岁。患者中以男性为主(n = 15)。术后随访包括术后第一天或第二天的脑磁共振成像(MRI),使用T2*, FLAIR和DWI序列确定“新鲜”栓塞性缺血性灶的存在并排除出血并发症。6个月后,进行对照临床检查,脑部计算机断层扫描或核磁共振成像,头部大动脉超声血管扫描。所有患者颈动脉通畅完全恢复,术后早期未发现复发性缺血性脑损伤的临床体征。在任何情况下均未发现斑块通过支架脱垂的迹象。在11例中,通过外部过滤器吸入时出现了大量的动脉粥样硬化碎片。3例远端保护滤过器也检出栓子。这一事实表明,在这种情况下,联合使用远端和近端抗栓塞系统可以可靠地防止栓塞的风险。根据第1天或第2天的MRI检查,没有“新鲜”亚临床栓塞性缺血性病灶的迹象,也没有出血。在20例接受随访检查的患者中,没有记录到任何情况下支架内再狭窄的迹象,以及反复的缺血性中风。在7例斑块有溃疡的病例中,溃疡在支架下消退。预计有三名患者将接受随访检查。根据远程调查,这些患者没有新的缺血性脑病变。三重抗栓塞保护技术在治疗次全超栓塞性危险颈动脉狭窄患者中的有效性,表现为无复发性缺血性病变的临床和神经影像学征象。三重抗栓塞保护技术治疗次全超栓塞性危性颈动脉狭窄安全有效。在这个最危险的人群中,颈动脉支架置入术的效果有所改善,这让我们有理由考虑揭示颈动脉支架置入术相对于颈动脉内膜切除术的优势。
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引用次数: 0
The approach to the management of a patient with chronic venous insufficiency in a specialized vascular center ‒ a combination of world guidelines and personal experience 在专门的血管中心治疗慢性静脉功能不全患者的方法-结合世界指南和个人经验
Pub Date : 2021-11-20 DOI: 10.26683/2786-4855-2021-2(36)-60-72
O. Voloshyn, O. Suzdalenko, V. Gubka, S. Machuskyi, O. Popova, S. Rasulzade
A lot of recommendations has been published regarding the treatment of chronic venous disease. At the same time, none of these documents reflects the complete «path» of the patient from the stage of the initial visit (diagnosis) to the choice of the optimal treatment option. Therefore, the creation of a protocol that would take into account on the one hand the most modern and proven effective approaches to diagnosis and treatment, and on the other hand, the individual characteristics of each clinical case is an urgent task.The main task of the publication is to create a practice-oriented instruction for the diagnosis, comprehensive treatment and prevention of chronic venous insufficiency. The management of a patient with chronic venous insufficiency is presented in the form of «AngioLife Venous Protocol®», a set of clear practical recommendations for vascular surgeon and phlebologist. This protocol is based on our own practical experience, existing protocols and guidelines for the treatment of patients with chronic venous insufficiency. The venous protocol includes four stages of a set of medical measures, the purpose of which is to form a clear program of further examination and treatment of the patient. Adherence to all the recommendations specified in the protocol allows to obtain satisfactory functional and cosmetic results of treatment of patients with chronic venous insufficiency with minimal risk of recurrence.
关于慢性静脉疾病的治疗,已经发表了很多建议。同时,这些文件都没有反映出患者从初次就诊(诊断)到选择最佳治疗方案的完整“路径”。因此,制定一项协议是一项紧迫的任务,该协议一方面考虑到最现代和最有效的诊断和治疗方法,另一方面考虑到每个临床病例的个体特征。本刊的主要任务是为慢性静脉功能不全的诊断、综合治疗和预防创造一种以实践为导向的指导。慢性静脉功能不全患者的管理以“AngioLife静脉协议®”的形式提出,这是一套针对血管外科医生和静脉学家的明确实用建议。本方案是基于我们自己的实践经验,现有的方案和指南的慢性静脉功能不全患者的治疗。静脉方案包括一套医疗措施的四个阶段,其目的是形成对患者进一步检查和治疗的明确方案。遵守协议中规定的所有建议,可以获得令人满意的功能和美容效果,治疗慢性静脉功能不全患者,复发风险最小。
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引用次数: 0
Neurological and medical complications in cerebral stroke patients before hospitalization and during admission to the clinic «oberig» stroke center 脑卒中患者住院前和住院期间的神经系统和医学并发症«oberig»中风中心
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-14-25
Y. Flomin
Objective ‒ to determine the rate of medical and neurological complications in patients with cerebral stroke (CS) before hospitalization and during in-patient treatment at the Stroke Center (SC), as well as to establish independent predictors for new medical complications at the SC, and to develop an appropriate prognostic model. Materials and methods. The study enrolled 539 patients, 309 (57.3 %) were men and 230 (42.7 %) were women. The age of patients ranged from 20.4 to 95.6 (66.0 [57.9; 75.1]) years. 438 (81.3 %) patients were diagnosed with ischemic stroke (177 (40.4%) ‒ atherothrombotic subtype, 200 (45.7 %) ‒ cardioembolic, 30 (6.9 %) – lacunar, 32 (7.0 %) ‒ stroke of other established or undetermined etiology), 101 (18.7 %) ‒ intracerebral hemorrhage. 109 (20.2%) of the study participants were hospitalized in the hyperacute period, 113 (21.0 %) ‒ in the acute, 199 (36.9 %) ‒ in the early subacute, 36 (6.7 %) ‒ in the late subacute, 82 (15.2%) ‒ in the remote (chronic) period of CS. All patients were evaluated upon admission using the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS). The method of construction and analysis of logistic regression models was used to quantify the degree of influence of factor features on the risk of complications. The analysis was performed using the package MedCalc v. 19.1. Results. The total NIHSS score on admission ranged from 0 to 39 (11 [6; 18]). Among the studied patients, 119 (22.1 %) had mild, 218 (40.5 %) – moderate, 114 (21.2 %) – severe, 88 (16.3 %) – very severe CS. Asesed with mRS upon admission, 11 (2.0 %) patients have 0 point, 34 (6.3 %) – 1 point, 58 (10.8 %) – 2 point, 65 (12.1 %) – 3 point,136 (25.2 %) – 4 point, and 235 (43.6 %) – 5 point. Neurological or medical complications before hospitalization occurred in 303 (56.2 %) patients, including 111 (20.6 %) patients with neurological complications and 192 (35.6 %) patients with medical ones. More than one complication was recorded in 52 (9.6 %) persons. The incidence of new neurological and medical complications during the SC stay was significantly lower (p<0.001) than before hospitalization. The independent predictors of new medical complications were CE subtype of IS (OR 2.08; 95 % CI 1.11–3.92), medical complications before admission (OR 2.58; 95 % CI 1.51–4.42), higher initial NIHSS score (OR 1.11; 95 % CI 1.06–1.16 for each additional point), and higher initial mRS (OR 1.62; 95 % CI 1.07–2.48, for each additional point). The predictive model based on the selected set of features has good sensitivity (86.4 %) and moderate specificity (68.4 %). The area under the operating characteristics curve AUC = 0.85 (95 % CI 0.82–0.88), indicates a strong relationship between this set of factorial factors and the risk of medical complications during in-patient treatment at the SC. Conclusions. Before SC admission, complications, mainly medical, occurred in the majo-rity of the patients. A higher rate of medica
目的:确定脑中风(CS)患者在住院前和在卒中中心(SC)住院治疗期间的医学和神经系统并发症的发生率,并建立新的医学并发症在SC的独立预测因素,并建立一个适当的预后模型。材料和方法。该研究纳入了539例患者,其中309例(57.3%)为男性,230例(42.7%)为女性。患者年龄20.4 ~ 95.6岁(66.0岁[57.9岁;75.1])。438例(81.3%)患者被诊断为缺血性卒中(其中177例(40.4%)为动脉粥样硬化血栓亚型,200例(45.7%)为心源性卒中,30例(6.9%)为腔隙性卒中,32例(7.0%)为其他已确定或未确定病因的卒中),101例(18.7%)为脑出血。109人(20.2%)在超急性期住院,113人(21.0%)在急性期住院,199人(36.9%)在亚急性早期住院,36人(6.7%)在亚急性晚期住院,82人(15.2%)在CS的远端(慢性)期住院。所有患者在入院时采用美国国立卫生研究院卒中量表(NIHSS)和改良Rankin量表(mRS)进行评估。采用logistic回归模型构建与分析的方法,量化因素特征对并发症发生风险的影响程度。使用MedCalc v. 19.1软件包进行分析。结果。入院时NIHSS总分为0 ~ 39分[6];18])。在研究的患者中,119例(22.1%)为轻度CS, 218例(40.5%)为中度CS, 114例(21.2%)为重度CS, 88例(16.3%)为极重度CS。入院时进行mRS评分,0分11例(2.0%),1分34例(6.3%),2分58例(10.8%),3分65例(12.1%),4分136例(25.2%),5分235例(43.6%)。住院前出现神经系统或内科并发症303例(56.2%),其中神经系统并发症111例(20.6%),内科并发症192例(35.6%)。52例(9.6%)患者出现1种以上并发症。与住院前相比,SC住院期间新发神经系统和内科并发症的发生率显著降低(p<0.001)。新发医学并发症的独立预测因子为IS CE亚型(OR 2.08;95% CI 1.11-3.92),入院前医疗并发症(OR 2.58;95% CI 1.51-4.42),初始NIHSS评分较高(OR 1.11;95% CI 1.06-1.16,每增加一个点),更高的初始mRS (OR 1.62;95% CI 1.07-2.48,每增加一个点)。基于所选特征集的预测模型具有良好的敏感性(86.4%)和中等的特异性(68.4%)。操作特征曲线下面积AUC = 0.85 (95% CI 0.82-0.88),表明这组因子与SC住院治疗期间医疗并发症的风险之间存在很强的关系。在SC入院前,大多数患者发生并发症,主要是医疗并发症。与严重CS相关的医疗并发症发生率较高,依赖性较大,年龄较大,从CS发病到SC入院的时间较长。SC的并发症发生率明显低于入院前,这表明在综合卒中单元护理的好处。
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引用次数: 0
Biophysical mechanisms of the formation of wound channels in non-penetrating gunshot craniocerebral wounds 非穿透性枪弹颅脑伤创面通道形成的生物物理机制
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-33-42
A.O. Danchyn, O. Goncharuk, S. Usatov, M.S. Altabury, G.O. Danchyn
Objective ‒ to develop recommendations for optimization of primary surgical treatment of gunshot penetrating craniocerebral wounds on the basis of theoretical and applied study of one of the sections of wound ballistics ‒ biophysical mechanisms of wound canal formation, concomitant impenetrable wounds and intracranial injuries.Materials and methods. The medical histories of 155 wounded who received a non-pe-netrating craniocerebral injury during the hostilities in the East of Ukraine in 2014‒2020 were studied. All of the wounded were males between 18 and 60 years old (mean age ‒ 35.1 years). To study the biophysical features of the formation of different types of wound canals at a given non-lethal kinetic energy transferred to the head tissues, the type of the wounding projectile, the flight trajectory, the nature of gunshot injuries to the soft tissues of the cranial vault and skull fractures and intracranial injuries were determined according to the data of clinical stu-dies and computed tomography and compared with the results of theoretical studies using the laws of wound ballistics.Results. There were 11 (7.1 %) bullet (only tangential) wounds, and 144 (92.9 %) shrapnel. The formation of wound channels depends on the type of the wounding projectile and its kinetic energy. Non-penetrating firearms bullet and shrapnel tangential craniocerebral wounds are caused by the destructive effect of injuring shells on the tissues, which at the moment of collision with the head have both destructive kinetic energy (>80 J) and less than destructive kinetic energy. Blind craniocerebral injuries are caused only by the traumatic effects of fragments with a small (<80 J) kinetic energy.Conclusions. With gunshot non-penetrating single shrapnel blind wounds, the wounds do not have a zone of secondary necrosis, and the zone of primary necrosis is small or insignificant, which makes it possible not to carve soft tissues around the wound during primary surgical treatment, but only to remove necrotic tissues. With gunshot non-penetrating shrapnel tangential and blind craniocerebral wounds, when the soft tissue wounds of the cranial vault do not gap, small size (damage to the skin, subcutaneous tissue to aponeurosis), primary surgical treatment is not performed. Such wounds are treated with a toilet and aseptic dressings. Wound canals ending in gunshot fractures are subject to primary surgical treatment in the same way as gunshot fractures.
目的:在创伤弹道学的理论和应用研究的基础上,对枪弹穿透性颅脑伤的初级外科治疗提出优化建议。该章节为创伤管形成、伴发不可穿透性创伤和颅内损伤的生物物理机制。材料和方法。对2014-2020年乌克兰东部敌对行动期间155名非中性颅脑损伤伤员的病史进行了研究。所有伤者均为18至60岁的男性(平均年龄- 35.1岁)。研究在传递给头部组织的非致死动能、致伤弹的类型、飞行轨迹等条件下,不同类型伤管形成的生物物理特征。根据临床研究资料和计算机断层扫描资料,结合创伤弹道学规律,与理论研究结果进行比较,确定颅底软组织损伤、颅骨骨折及颅内损伤的性质。有11例(7.1%)枪伤,144例(92.9%)弹片伤。伤道的形成取决于伤弹的类型及其动能。非穿透性火器子弹和弹片切向颅脑损伤是由伤弹对组织的破坏作用造成的,在与头部碰撞的瞬间既有破坏动能(>80 J),也有破坏动能小于破坏动能。盲目性颅脑损伤仅由小(<80 J)动能碎片的创伤效应引起。对于枪弹非穿透性单片致盲伤口,伤口没有继发坏死区,且原发坏死区较小或不明显,这使得在初级手术治疗时可以不切割伤口周围的软组织,而只切除坏死组织。伴枪弹非穿透力弹片切向性致盲颅脑创伤,当软组织创面的颅拱顶不间隙、尺寸小(损伤皮肤、皮下组织至腱膜)时,不进行初级手术治疗。这种伤口要用厕所和无菌敷料处理。以枪伤骨折结束的伤口管与枪伤骨折一样,需要进行初级手术治疗。
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引用次数: 0
Free-floating thrombus and a fragment of atherosclerotic plaque in the lumen of the internal carotid artery – review of 2 cases 颈内动脉腔内自由漂浮血栓和动脉粥样硬化斑块碎片——附2例报告
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-56-65
S. Konotopchyk, F. H. Rzayeva, O. Pastushyn, N. M. Nosenko, O.Ye. Svyrydiuk, M. Mamonova, I. Al-Kashkish
Free-floating thrombus or a fragment of atherosclerotic plaque (mobile plaque) in the lumen of the carotid artery is extremely rare. Atherosclerosis is the most common cause underlying their occurrence. The optimal treatment strategy has not been developed, at least in part due to the rarity of observations, as well as the lack of comparative studies between conservative and surgical treatment (carotid artery stenting, endovascular thrombectomy, endarterectomy). We present two cases that demonstrate the treatment tactics of these rather rare pathologies. Patient Yu., 62 years old, was hospitalized with focal neurological symptoms, National Institutes of Health Stroke Scale of 12. According to the CT of the brain, signs of an ischemic stroke in the right middle cerebral artery circulation were detected. Selective cerebral angiography diagnosed thrombosis of the arteries of the precentral and central sulcus of the right middle cerebral artery, critical stenosis of the mouth of the right internal carotid artery, and a free-floating thrombus in its lumen with a fixation point at the level of atherosclerotic plaque, which blocked the lumen of the artery by more than 60 %. Endovascular aspiration of a free-floating thrombus was performed, followed by angioplasty and stenting of critical stenosis with a favorable clinical outcome. Patient L., 73 years old, applied for carotid ultrasonography, during which a mobile atherosclerotic plaque was diagnosed at the level of the bifurcation of the right common carotid artery. Digital selective cerebral angiography confirmed a plaque fragment floating in the lumen of the artery. After applying a loading dose of ticagrelor without complications, an emergency implantation of a carotid stent was performed at the level of the bifurcation of the right common carotid artery.Taking into account the modern possibilities of interventional radiology and a wide range of tools, the endovascular approach to the treatment of complicated atherosclerotic plaque with a floating component or a formed blood clot is the best treatment option with a good safety profile.
颈动脉腔内自由漂浮的血栓或动脉粥样硬化斑块碎片(可移动斑块)极为罕见。动脉粥样硬化是其发生的最常见原因。目前还没有最佳的治疗策略,至少部分原因是缺乏观察,以及缺乏保守治疗和手术治疗(颈动脉支架置入术、血管内血栓切除术、动脉内膜切除术)之间的比较研究。我们提出两个案例,证明这些相当罕见的病理的治疗策略。病人于。患者,62岁,因局灶性神经症状住院,美国国立卫生研究院卒中分级为12级。根据脑部CT,发现右脑中动脉循环缺血性中风的征象。选择性脑血管造影诊断为右侧大脑中动脉中央前沟和中央沟动脉血栓形成,右侧颈内动脉口部严重狭窄,其管腔内有游离血栓,固定点在动脉粥样硬化斑块水平,阻塞动脉管腔60%以上。血管内抽吸游离血栓,然后对严重狭窄进行血管成形术和支架置入术,临床结果良好。患者L, 73岁,行颈动脉超声检查,在右侧颈总动脉分叉处发现一移动的动脉粥样硬化斑块。数字选择性脑血管造影证实动脉腔内漂浮斑块碎片。应用负荷剂量替格瑞洛后,无并发症,在右颈总动脉分叉处紧急植入颈动脉支架。考虑到介入放射学的现代可能性和广泛的工具,血管内入路治疗具有漂浮成分或形成血栓的复杂动脉粥样硬化斑块是具有良好安全性的最佳治疗选择。
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引用次数: 0
Radiosurgical treatment of residual and recurrent pituitary adenomas 残留及复发垂体腺瘤的放射外科治疗
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-26-32
O. Voznyak, O. S. Silaieva, M. Polishchuk, N. Hryniv
Objective ‒ the treatment result estimation of subtotally removed and recurrent pituitary adenomas using different algorithms of radiotherapy and radiosurgery.Materials and methods. The retrospective analysis of 21 cases of pituitary adenomas was performed. There were 11 women and 10 men included. The average age was 45 (from 18 to 72) years. All patients had relapse or residual tumor after incomplete surgical removal. The method of irradiation was chosen by a radiologist. Tumor size control was assessed by an independent radiologist in 3 months and 1 year after treatment. Endocrine function was estimated by an independent endocrinologist in 3 months and 1 year after treatment.Results. Following transsphenoidal removal ‒ 13 patients (4 were operated twice), 5 after cranial surgery and 3 were operated sequentially transnasally and transcranially. Irradiation of 14 cases of residual tumor was performed no later than 6 months after surgery. The mean term of treatment start of recurrent adenomas was 12 months (8‒17) after surgery. VARIAN Novalis was applied in 16 cases, VARIAN Clinac iX in 4 cases and VARIAN TrueBeam STx was used once. Single and total radiation doses were determined individually. None of patients had visual impairment after treatment. The hypopituitarism deterioration was not noted as well.Conclusions. Hypofractionated stereotactic radiosurgery allows to bring a high dose of radiation to the pituitary adenomas, minimizing damage to the visual pathways, the pituitary gland and infundibulum. As the sequence, it reduces the toxicity of the technique. The application of modern radiation technologies minimize the irradiation of healthy surrounding tissues and reduce the negative effects of treatment.
目的:评价垂体次全切除及复发性腺瘤不同放疗和放外科治疗方法的疗效。材料和方法。对21例垂体腺瘤进行回顾性分析。其中包括11名女性和10名男性。平均年龄为45岁(18 - 72岁)。所有患者术后均有复发或肿瘤残留。照射的方法是由一位放射科医生选定的。肿瘤大小控制由独立放射科医生在治疗后3个月和1年进行评估。在治疗后3个月和1年由独立内分泌专家评估内分泌功能。经蝶窦切除后13例(2次手术4例),颅脑手术5例,经鼻、经颅连续手术3例。14例残余肿瘤的放射治疗不迟于术后6个月。复发性腺瘤的平均治疗开始时间为术后12个月(8-17)。16例使用VARIAN Novalis, 4例使用VARIAN Clinac iX, 1例使用VARIAN TrueBeam STx。单次和总辐射剂量分别测定。治疗后所有患者均无视力障碍。垂体功能减退也未见明显恶化。低分割立体定向放射手术允许将高剂量的辐射带到垂体腺瘤,最大限度地减少对视觉通路,垂体和垂体的损害。按照这个顺序,它减少了这项技术的毒性。现代放射技术的应用最大限度地减少了对周围健康组织的照射,减少了治疗的负面影响。
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引用次数: 0
Possibility of increasing the «therapeutic window» for revascularization of the carotid arteries in the acute period of ischemic stroke 缺血性卒中急性期增加颈动脉血运重建“治疗窗口”的可能性
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-43-49
O. Spinul, O. Kartashov, O.O. Shpak
Objective ‒ to assess the possibility of increasing the time of surgical restoration of blood flow in the acute period of ischemic stroke due to occlusive lesion of the internal carotid artery (ICA).Materials and methods. Among the patients who were admitted for treatmentat in the Regional Odessa Hospital with acute ischemic stroke in the carotid region a group of 6 patients was identified in whom the cause of stroke was occlusion of the ICA by an atherosclerotic plaque. Age of patients ‒ from 54 to 71 years. Patients were hospitalized later 6 hours from the onset of stroke. The survey was carried out according to the established protocol. Neurological deficits are mild to moderate. In order to eliminate the occlusion of the ICA, all patients underwent endarterectomy.Results. Carotidendarterectomy was performed from 2 to 11 days after onset of stroke. Retrograde blood flow through the ICA was obtained in three (50 %) patients in whom surgical interventions were performed up to 4 days after the disease. In the postoperativeperiod a typical therapy was carried out. In cases with the obtained retrograde blood flowon control carotid angiograms demonstrated revascularization of the ICA basin according to mTICI-3. On the control CT of the brain in postoperative period in one case the point subarachnoid hemorrhages was determined. In the other two cases there was no evidence hemorrhagic transformation. Operated patients showed positive dynamics: a decrease hemiparesis by 1 poin and regression of mental disorders. The patients were discharged withm RS 1‒2. During the follow-up examination 90 days the neurological condition of the patients improved to mRS 1‒0.Conclusions. Results obtained in increasing the “therapeutic window” for revascularization of the occluded ICA allow to continue research in the indicated direction and improve the quality of surgical care for patients with acute stroke.
目的:探讨在颈内动脉闭塞性脑卒中急性期延长手术恢复血流时间的可行性。材料和方法。在敖德萨地区医院接受治疗的颈动脉急性缺血性中风患者中,有6例患者被确定为中风的原因是动脉粥样硬化斑块阻塞了ICA。患者年龄- 54 - 71岁。患者在中风发作后6小时住院。调查是按照既定的程序进行的。神经功能缺损是轻度到中度的。为了消除ICA阻塞,所有患者均行动脉内膜切除术。颈动脉切除术于卒中发生后2 ~ 11天进行。3例(50%)患者在发病后4天内进行了手术,经ICA获得逆行血流。术后进行典型治疗。在获得逆行血流控制的病例中,颈动脉血管造影显示根据mTICI-3, ICA盆地血运重建。术后脑CT对照片确定1例蛛网膜下腔出血点。在另外两个病例中没有出血转化的证据。手术患者表现出积极的动态:偏瘫减少1分,精神障碍消退。患者出院时RS 1-2。随访90 d,患者神经系统状况改善至mRS 1 ~ 0。在增加闭塞ICA血运重建的“治疗窗口”方面获得的结果,允许在指明的方向上继续研究,并提高急性卒中患者的手术护理质量。
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引用次数: 0
To the issue of degree of removal of gliomas of supratentorial localization 探讨幕上胶质瘤的切除程度
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-50-55
S. Usatov, B. Rashidi, Y. Boguslavskiy
Objective ‒ to assess the possibility of increasing the time of surgical restoration of blood flow in the acute period of ischemic stroke due to occlusive lesion of the internal carotid artery (ICA).Materials and methods. Among the patients who were admitted for treatmentat in the Regional Odessa Hospital with acute ischemic stroke in the carotid region a group of 6 patients was identified in whom the cause of stroke was occlusion of the ICA by an atherosclerotic plaque. Age of patients ‒ from 54 to 71 years. Patients were hospitalized later 6 hours from the onset of stroke. The survey was carried out according to the established protocol. Neurological deficits are mild to moderate. In order to eliminate the occlusion of the ICA, all patients underwent endarterectomy.Results. Carotidendarterectomy was performed from 2 to 11 days after onset of stroke. Retrograde blood flow through the ICA was obtained in three (50 %) patients in whom surgical interventions were performed up to 4 days after the disease. In the postoperativeperiod a typical therapy was carried out. In cases with the obtained retrograde blood flowon control carotid angiograms demonstrated revascularization of the ICA basin according to mTICI-3. On the control CT of the brain in postoperative period in one case the point subarachnoid hemorrhages was determined. In the other two cases there was no evidence hemorrhagic transformation. Operated patients showed positive dynamics: a decrease hemiparesis by 1 poin and regression of mental disorders. The patients were discharged withm RS 1‒2. During the follow-up examination 90 days the neurological condition of the patients improved to mRS 1‒0.Conclusions. Results obtained in increasing the “therapeutic window” for revascularization of the occluded ICA allow to continue research in the indicated direction and improve the quality of surgical care for patients with acute stroke.
目的:探讨在颈内动脉闭塞性脑卒中急性期延长手术恢复血流时间的可行性。材料和方法。在敖德萨地区医院接受治疗的颈动脉急性缺血性中风患者中,有6例患者被确定为中风的原因是动脉粥样硬化斑块阻塞了ICA。患者年龄- 54 - 71岁。患者在中风发作后6小时住院。调查是按照既定的程序进行的。神经功能缺损是轻度到中度的。为了消除ICA阻塞,所有患者均行动脉内膜切除术。颈动脉切除术于卒中发生后2 ~ 11天进行。3例(50%)患者在发病后4天内进行了手术,经ICA获得逆行血流。术后进行典型治疗。在获得逆行血流控制的病例中,颈动脉血管造影显示根据mTICI-3, ICA盆地血运重建。术后脑CT对照片确定1例蛛网膜下腔出血点。在另外两个病例中没有出血转化的证据。手术患者表现出积极的动态:偏瘫减少1分,精神障碍消退。患者出院时RS 1-2。随访90 d,患者神经系统状况改善至mRS 1 ~ 0。在增加闭塞ICA血运重建的“治疗窗口”方面获得的结果,允许在指明的方向上继续研究,并提高急性卒中患者的手术护理质量。
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引用次数: 0
Experience in treating patients with a combination of the descending aorta saccular aneurysm and spondylodiscitis 治疗降主动脉囊性动脉瘤合并脊柱炎的经验
Pub Date : 2021-06-30 DOI: 10.26683/2786-4855-2021-1(35)-66-71
M. Tonchev, V.M. Muzhevska, О.M. Bezkorovainyy, V.M. Mitchenok, V. Kravchenko
The article presents a clinical case of treatment of a patient with spondylodiscitis of two levels – thoracic and lumbar spine spondylodiscitis combined with the thoracic aorta aneurysm. A 68-year-old patient was hospitalized in the Neurosurgical Department of the M.V. Sklifosovsky Poltava Regional Clinical Hospital in August 2019 with complaints of pain and discomfort in the thoracic and lumbar spine, shoulder joints, severe weakness in the lower extremities. The multislice computed tomography with intravenous contrast revealed a sac-like aneurysm of the descending thoracic aorta at the level of vertebrae Th4-Th5 with invasion into the vertebral bodies, spondylodiscitis of vertebrae Th4-Th5 and Th11-Th12 with deformation of the spinal axis, the formation of absolute stenosis of the spinal canal at the level of vertebrae Th11-Th12. At the first stage of the surgery, the thoracic aortic arthroplasty was performed using TAA Stent Graft System (Ankura, China) 34 × 34 × 160 mm at the M.M. Amosov National Institute of Cardiovascular Surgery and the exclusion of the descending aorta aneurysm from the bloodstream was maintained. At the second stage, transpedicular stabilization of the spine at the level of vertebrae Th10-Th11-L2-L3 was performed at the M.V. Sklifosovsky Poltava Regional Clinical Hospital using Legacy system (Medtronic, USA) and spinal cord compression was eliminated. The treatment of spondylodiscitis at the level of the vertebrae Th4-Th5 was conservative with the use of osteotropic antibacterial drugs. The patient was mobilized in the early post-surgical period after stabilization of the spine. Regression of pain syndrome and lower paraparesis was noted. Further observation was performed on an outpatient basis. According to the modified Rankin Scale, which allows assessing the degree of independence of the patient in everyday life, the patient was evaluated with 3 points at discharge. A follow-up examination at 3, 12, and 24 months showed that the functioning of the stent-graft and transpedicular system were satisfactory. The result of 0 points according to the modified Rankin Scale.Patients with the thoracic spine spondylodiscitis require special attention and additional diagnostic procedures. The risk of additional combined pathology in the form of thoracic and abdominal aorta aneurysms should be considered when planning surgical treatment.
本文介绍了治疗胸、腰椎两节段脊柱炎合并胸主动脉动脉瘤的临床病例。一名68岁的患者于2019年8月在M.V.斯克利夫索夫斯基波尔塔瓦地区临床医院神经外科住院,主诉胸椎、腰椎、肩关节疼痛和不适,下肢严重无力。多层螺旋ct静脉显像示Th4-Th5椎体水平胸降主动脉囊状动脉瘤浸润椎体,Th4-Th5、Th11-Th12椎体椎间盘炎伴脊柱轴变形,Th11-Th12椎体水平椎管绝对狭窄形成。在手术的第一阶段,在M.M. Amosov国立心血管外科研究所使用TAA支架系统(Ankura, China) 34 × 34 × 160 mm进行胸主动脉关节置换术,并保持降主动脉动脉瘤与血流的隔离。在第二阶段,在M.V. Sklifosovsky Poltava地区临床医院使用Legacy系统(美敦力,美国)对Th10-Th11-L2-L3椎体水平的脊柱进行经椎弓根稳定,并消除脊髓压迫。对于Th4-Th5椎体水平的脊柱炎,采用促骨抗菌药物保守治疗。患者在脊柱稳定后的术后早期活动。观察到疼痛综合征和下肢麻痹的消退。在门诊基础上进行进一步观察。根据改进的兰金量表(Rankin Scale)评估患者在日常生活中的独立程度,患者出院时被评估为3分。3、12和24个月的随访检查显示支架移植物和经椎弓根系统的功能令人满意。根据修改后的兰金量表0分的结果。胸椎椎间盘炎患者需要特别注意和额外的诊断程序。在计划手术治疗时,应考虑到以胸腹主动脉动脉瘤形式出现的其他联合病理的风险。
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引用次数: 0
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Ukrainian Interventional Neuroradiology and Surgery
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