Objective: To observe and explore the effects and mechanism of apoptosis on canine induced by Laser. Try to find a new approach to treat of armpit odor with no traumatism. Method: We used different power of semiconductor Laser to irradiate the black hair canine to observe and evaluate the tissue effects with electroscope, flow cytometry and Tunel technique at different period of time after irradiation. Result: The apoptosis has been observed within the hair follicle cells and apocrine gland cells after irradiation. After repeat irradiation in low power level, more apoptosis has been observed. Conclusion: Apoptosis exists in hair follicle cells and apocrine gland cells after Laser irradiation.
{"title":"Experimental study on apoptosis induced by semiconductor laser to hair removal and armpit odor treatment","authors":"Hongmin Shi, Min Yan, Meijue Zhang","doi":"10.1117/12.639199","DOIUrl":"https://doi.org/10.1117/12.639199","url":null,"abstract":"Objective: To observe and explore the effects and mechanism of apoptosis on canine induced by Laser. Try to find a new approach to treat of armpit odor with no traumatism. Method: We used different power of semiconductor Laser to irradiate the black hair canine to observe and evaluate the tissue effects with electroscope, flow cytometry and Tunel technique at different period of time after irradiation. Result: The apoptosis has been observed within the hair follicle cells and apocrine gland cells after irradiation. After repeat irradiation in low power level, more apoptosis has been observed. Conclusion: Apoptosis exists in hair follicle cells and apocrine gland cells after Laser irradiation.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117346316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To observe the effect of Ho:YAG laser in treatment of urethra cauncle. Methods: The patients suffering from urethra cauncle were treated by Ho:YAG laser, the energy of per pulse is 0.5J. The frequency of pulse is 5~15Hz, and the average power of the laser is 2.5~7.5W. Results: Among the patients 188 cases of urethra cauncle were only cured for one time, twice for 12 cases. No stricture on the peristome of urethra or urethrovaginal fistula was observed. Conclusions: The technique of treatment of urethra cauncle with Ho:YAG laser is an effect and safe therapeutics with the merit of excellent homeostasis, improved visualization, minimal thermal damage to surrounding tissue, shorter period of recovery and easy to operate. It is better than CO2 laser and Nd:YAG laser.
{"title":"Analysis on the effect of urethra caruncle treated by Ho:YAG laser","authors":"Meijue Zhang, Jing Zhu, Hongmin Shi","doi":"10.1117/12.639370","DOIUrl":"https://doi.org/10.1117/12.639370","url":null,"abstract":"Objective: To observe the effect of Ho:YAG laser in treatment of urethra cauncle. Methods: The patients suffering from urethra cauncle were treated by Ho:YAG laser, the energy of per pulse is 0.5J. The frequency of pulse is 5~15Hz, and the average power of the laser is 2.5~7.5W. Results: Among the patients 188 cases of urethra cauncle were only cured for one time, twice for 12 cases. No stricture on the peristome of urethra or urethrovaginal fistula was observed. Conclusions: The technique of treatment of urethra cauncle with Ho:YAG laser is an effect and safe therapeutics with the merit of excellent homeostasis, improved visualization, minimal thermal damage to surrounding tissue, shorter period of recovery and easy to operate. It is better than CO2 laser and Nd:YAG laser.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116414350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nowadays, much attention has been paid to keep long-term patency after vascular anastomosis especially for small-caliber vessels in vascular surgery. From these standpoints, low energy CO2 laser was used to make an anastomosis especially for small-caliber vessels. And then an availability of vascular anastomosis by laser could be apparently recognized.
{"title":"Laser application in the field of vascular anastomosis: experimental and clinical study","authors":"M. Okada","doi":"10.1117/12.639343","DOIUrl":"https://doi.org/10.1117/12.639343","url":null,"abstract":"Nowadays, much attention has been paid to keep long-term patency after vascular anastomosis especially for small-caliber vessels in vascular surgery. From these standpoints, low energy CO2 laser was used to make an anastomosis especially for small-caliber vessels. And then an availability of vascular anastomosis by laser could be apparently recognized.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128533790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To explore the feasibility and clinical value of treatment for intranasal synechiae by CO2 laser with reduce the incidence of complication in endoscopic sinus surgery. Methods A retrospective study was made of 31 cases treated for intranasal synechiae by CO2 laser. A CO2 laser was used to facilitate removed intranasal adhesion between the middle turbinate and the lateral nasal wall with minimal blood loss under endoscopic visualization. Results 31 cases were followed up beyond 24 months. The overall effective rate was 90.3%. 3 patients underwent a revision endoscopic procedure. Conclusions The method has many advantages such as clear operative field, safe and satisfactory. So it is a good way to treatment for intranasal synechiae.
{"title":"Treatment for intranasal synechiae by CO2 laser under endoscopic visualization","authors":"Yunhai Feng, S. Yin","doi":"10.1117/12.639313","DOIUrl":"https://doi.org/10.1117/12.639313","url":null,"abstract":"Objective To explore the feasibility and clinical value of treatment for intranasal synechiae by CO2 laser with reduce the incidence of complication in endoscopic sinus surgery. Methods A retrospective study was made of 31 cases treated for intranasal synechiae by CO2 laser. A CO2 laser was used to facilitate removed intranasal adhesion between the middle turbinate and the lateral nasal wall with minimal blood loss under endoscopic visualization. Results 31 cases were followed up beyond 24 months. The overall effective rate was 90.3%. 3 patients underwent a revision endoscopic procedure. Conclusions The method has many advantages such as clear operative field, safe and satisfactory. So it is a good way to treatment for intranasal synechiae.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130346166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To evaluate the biological effect of Nd:YAP laser in different power and irradiation time on canine stomach in vitro. Methods: The canine stomach in vitro was irradiated by Nd:YAP laser with different power and irradiation time. The damage with naked eye, micro and ultramicro structure was observed. Results: The thermal coagulation effect is mostly and the ablation effect is subordinate on biological effect of Nd:YAP laser on canine stomach in vitro. Thermal coagulation and denaturalization time of whole stratum in pathology is 10W, 5s; 20W, 4s; 30W, 2s; 40~60W, 1s. Conclusions: Safety dose of laser beam on canine stomach in vitro is 10W, time less than 5s; 20W, time less than 4s; 30W, time less than 2s. The ablation and thermal coagulation effects of Nd:YAP laser on canine stomach in vitro is positive correlative with power and time.
{"title":"Experimental study of biological effect on canine stomach in vitro by Nd:YAP laser","authors":"Meijue Zhang, Jing Zhu, Hui-guo Zhang","doi":"10.1117/12.639192","DOIUrl":"https://doi.org/10.1117/12.639192","url":null,"abstract":"Objective: To evaluate the biological effect of Nd:YAP laser in different power and irradiation time on canine stomach in vitro. Methods: The canine stomach in vitro was irradiated by Nd:YAP laser with different power and irradiation time. The damage with naked eye, micro and ultramicro structure was observed. Results: The thermal coagulation effect is mostly and the ablation effect is subordinate on biological effect of Nd:YAP laser on canine stomach in vitro. Thermal coagulation and denaturalization time of whole stratum in pathology is 10W, 5s; 20W, 4s; 30W, 2s; 40~60W, 1s. Conclusions: Safety dose of laser beam on canine stomach in vitro is 10W, time less than 5s; 20W, time less than 4s; 30W, time less than 2s. The ablation and thermal coagulation effects of Nd:YAP laser on canine stomach in vitro is positive correlative with power and time.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116391280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Several photosensitisers are known to accumulate selectively in atheromas, regardless of the size of the involved artery. The new photosensitizer, mono-L-aspartyl chlorin e6 (NPe6), specifically accumulates in the atheroma. In the presence of NPe6, the atheroma could be recognized by detecting the specific fluorescence spectrum of NPe6 using a spectrophotometer. We developed a spectrum analysis system and reported that the fluorescence spectra of NPe6 emitted from atherosclerotic plaques on the descending thoracic aorta were recognized by this analysis system with an angioscopic approach in the animal model of atherosclerosis. We also detected the fluorescence spectrum peak at 675 nm of NPe6 laparoscopically only in parts of the abdominal aorta with an atheroma. This spectrum analysis system is useful to recognize the atheroma, but not to recognize the atherosclerotic lesions of the artery as a whole. So, we developed a fluorescence endoscope. Using the endoscopic analysis system, atheromas on the carotid artery were visualized as reddish spots from inside and outside the artery. Then we developed an epifluorescence stereoscope system, and using this device we visualized small coronary atherosclerosis specifically at the beating heart surface. We extensively examined the effects of photodynamic therapy with NPe6 on the atheroma. We studied the change in the lipid components of the atheroma using Fourier transform infrared (FTIR) microspectroscopy. FTIR microspectroscopic analysis showed a dissociation of ester bonds of cholesterol esters in the atheroma after photodynamic therapy. The framework of the atheroma and the lipids accumulated in the atheroma were destroyed. We also evaluated the change in the elastic framework in the atheroma using scanning electron microscopy. The destruction of the architecture of the elastic fiber network in the atheroma was revealed.
{"title":"Basic research in PDT","authors":"J. Hayashi, K. Aizawa","doi":"10.1117/12.639219","DOIUrl":"https://doi.org/10.1117/12.639219","url":null,"abstract":"Several photosensitisers are known to accumulate selectively in atheromas, regardless of the size of the involved artery. The new photosensitizer, mono-L-aspartyl chlorin e6 (NPe6), specifically accumulates in the atheroma. In the presence of NPe6, the atheroma could be recognized by detecting the specific fluorescence spectrum of NPe6 using a spectrophotometer. We developed a spectrum analysis system and reported that the fluorescence spectra of NPe6 emitted from atherosclerotic plaques on the descending thoracic aorta were recognized by this analysis system with an angioscopic approach in the animal model of atherosclerosis. We also detected the fluorescence spectrum peak at 675 nm of NPe6 laparoscopically only in parts of the abdominal aorta with an atheroma. This spectrum analysis system is useful to recognize the atheroma, but not to recognize the atherosclerotic lesions of the artery as a whole. So, we developed a fluorescence endoscope. Using the endoscopic analysis system, atheromas on the carotid artery were visualized as reddish spots from inside and outside the artery. Then we developed an epifluorescence stereoscope system, and using this device we visualized small coronary atherosclerosis specifically at the beating heart surface. We extensively examined the effects of photodynamic therapy with NPe6 on the atheroma. We studied the change in the lipid components of the atheroma using Fourier transform infrared (FTIR) microspectroscopy. FTIR microspectroscopic analysis showed a dissociation of ester bonds of cholesterol esters in the atheroma after photodynamic therapy. The framework of the atheroma and the lipids accumulated in the atheroma were destroyed. We also evaluated the change in the elastic framework in the atheroma using scanning electron microscopy. The destruction of the architecture of the elastic fiber network in the atheroma was revealed.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129696639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The effects of intravascular low level laser irradiation of He-Ne on rat MCAo-induced cerebral injury were studied. The results showed that control rats (subjected to MCAo injury without laser treatment) at 7d exhibited striatal and cortical brain infarction in the right hemisphere from approximately 3 to 11mm from the front pole. the total infarct volume in this group was 34.5±8.1mm3. For experimental rats (with laser management), the total infarct volume was 29.0±9.0mm3. P was gained less than 0.05. The neurological score of control group was 4.7±0.6 and it was 5.2±1.0 in experimental group, comparison by statistical analysis showed P less than 0.05. The cerebral pathological damages in the control group were more severe than in experimental group. We concluded that the intravascular low level laser irradiation has no remarked complication and is helpful to reduce ischemic damage. There is clinically potential for the application of intravascular He-Ne low level laser irradiation in ischemia stroke.
{"title":"The neuroprotective effects of intravascular low level laser irradiation on cerebral ischemia rats","authors":"Yongming Qiu, Zhaofeng Lu, Zhongguan Wang, Ji-yao Jiang","doi":"10.1117/12.639317","DOIUrl":"https://doi.org/10.1117/12.639317","url":null,"abstract":"The effects of intravascular low level laser irradiation of He-Ne on rat MCAo-induced cerebral injury were studied. The results showed that control rats (subjected to MCAo injury without laser treatment) at 7d exhibited striatal and cortical brain infarction in the right hemisphere from approximately 3 to 11mm from the front pole. the total infarct volume in this group was 34.5±8.1mm3. For experimental rats (with laser management), the total infarct volume was 29.0±9.0mm3. P was gained less than 0.05. The neurological score of control group was 4.7±0.6 and it was 5.2±1.0 in experimental group, comparison by statistical analysis showed P less than 0.05. The cerebral pathological damages in the control group were more severe than in experimental group. We concluded that the intravascular low level laser irradiation has no remarked complication and is helpful to reduce ischemic damage. There is clinically potential for the application of intravascular He-Ne low level laser irradiation in ischemia stroke.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125321693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To obtain a new therapy for port-wine stain (PWS) with good effect and few side effects, the Leghorn chicken combs chosen as the animal models and treated by small dose HpD and variable pulsed 532nm laser were evaluated clinically using four different scoring systems commonly used in previous publication. Result: It was shown significant difference among 5 groups (p<0.01), and the treatment groups have better effect than the control groups. There's also difference among the four treatment groups and the higher dose of HpD has better effect. In all groups the higher the fluency of laser was used, the better the effect produce. Conclusion: The results provide evidence that small dose HpD and variable pulsed 532nm laser can increase the efficacy of treatment in PWS. Increasing the fluency of laser and the dose of HpD can improve the efficacy.
{"title":"Experimental study on port-wine stain treated by small dose HpD and variable pulsed 532nm laser","authors":"Meixiang Qin, Jing Zhu, Xiawen Yuan","doi":"10.1117/12.639245","DOIUrl":"https://doi.org/10.1117/12.639245","url":null,"abstract":"To obtain a new therapy for port-wine stain (PWS) with good effect and few side effects, the Leghorn chicken combs chosen as the animal models and treated by small dose HpD and variable pulsed 532nm laser were evaluated clinically using four different scoring systems commonly used in previous publication. Result: It was shown significant difference among 5 groups (p<0.01), and the treatment groups have better effect than the control groups. There's also difference among the four treatment groups and the higher dose of HpD has better effect. In all groups the higher the fluency of laser was used, the better the effect produce. Conclusion: The results provide evidence that small dose HpD and variable pulsed 532nm laser can increase the efficacy of treatment in PWS. Increasing the fluency of laser and the dose of HpD can improve the efficacy.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122895238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hong Wang, Yunlong Wei, Qi Zhou, Shengping Liu, J. Chui
Optical glucose measurement is an attractive research topic for years. One of the goals is to develop a noninvasive monitoring of long term, instantaneous blood glucose for diabetics. The principle of porlarimetry for glucose detection is introduced and several techniques of microdegree porlarimetry for glucose detection are summarized and the facts that effect measurement are discussed. Current and future research is focusing on the elimination of confounding factors such as other optically active substances for precise glucose detection.
{"title":"Microdegree porlarimetry for glucose concentrations detection","authors":"Hong Wang, Yunlong Wei, Qi Zhou, Shengping Liu, J. Chui","doi":"10.1117/12.639163","DOIUrl":"https://doi.org/10.1117/12.639163","url":null,"abstract":"Optical glucose measurement is an attractive research topic for years. One of the goals is to develop a noninvasive monitoring of long term, instantaneous blood glucose for diabetics. The principle of porlarimetry for glucose detection is introduced and several techniques of microdegree porlarimetry for glucose detection are summarized and the facts that effect measurement are discussed. Current and future research is focusing on the elimination of confounding factors such as other optically active substances for precise glucose detection.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132013764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The first Chinese ruby laser was created in 1961 and it was adopted for the retina coagulation experiment in 1965. Since 1970's, lasers had been widely applied clinically including the diseases suitable to physical therapy or acupuncture. The Chinese HpD was first produced in 1981 and first case of PDT was treated using Chinese HpD and Chinese lasers in the same year. Its success brought attention establishing a research group supported by the government in 1982. A nationwide systemic research project on PDT was then carried out. The step taken for PDT also accelerated the development of various fields of laser medicine and surgery. Laser treatments had been commonly adopted in the clinics and hospitals for the diseases of the superficial lesions and the lesions can be reached by the endoscopes non-invasively in 1980's. Since 1990's, the interventional laser therapies adopted mainly were percutaneous laser angioplasty, laser treatments through laparoscope, thoracoscope, arthroscope, neuro-endoscope etc. Ultrasound guided percutaneous laser heat coagulation for small hepatic cancer revealed good results and ultrasound guided percutaneous PDT for advanced large liver cancer revealed unexpected results after five years follow-up. At present: There are more long-term follow-up patients in the clinical trial; more advanced commercial available lasers and new techniques are adopted. Since the popularization of scanning electron microscope, laser scanning confocal microscope, laser induced auto-fluorescence system, high sensitivity fluorescence microscopic imaging system etc. in the laboratories, the basic studies can be more advanced and some times, the sub-cellular level can be reached; ultra-structure histo-morphology and gene studies are involved. In dermatology, Q-switched Alexandrite laser and other Q-switched lasers are used mainly for the treatment of skin pigmentation and vascular diseases; pulsed dye laser, ultra-pulsed CO2 laser are used in resurfacing, facial acne scar, osmidrosis etc. For ophthalmology, excimer laser are used for myopia or hyperopia; argon green laser, krypton yellow laser are adopted in coagulation for retinal detachment and neovascularization etc. Lasers are often used for the canaliculoplasty in the lacrimal canal. Low level lasers had been used very often on the acupuncture points and for many chronic diseases. Intravascular low level laser irradiation adopting semiconductor lasers and He-Ne laser were reported to use for comatose patients, schizophrenia, vascular dementia, Alzeimer's disease and coronary disease. Reports from laboratory studies in the field of low level laser demonstrated the stimulation effect on the cells and immunology system; inhibitory effect on proliferation; it improved the biomedical data in hemorrheology; promoted the spinal motor nerve cell function, axonal regeneration; increased epidermal Langerhams cell to improve the antigen function, increased myocardial capillary permeability. Intra-cor
{"title":"The development of laser surgery and medicine in China","authors":"Mingzhe Chen","doi":"10.1117/12.639086","DOIUrl":"https://doi.org/10.1117/12.639086","url":null,"abstract":"The first Chinese ruby laser was created in 1961 and it was adopted for the retina coagulation experiment in 1965. Since 1970's, lasers had been widely applied clinically including the diseases suitable to physical therapy or acupuncture. The Chinese HpD was first produced in 1981 and first case of PDT was treated using Chinese HpD and Chinese lasers in the same year. Its success brought attention establishing a research group supported by the government in 1982. A nationwide systemic research project on PDT was then carried out. The step taken for PDT also accelerated the development of various fields of laser medicine and surgery. Laser treatments had been commonly adopted in the clinics and hospitals for the diseases of the superficial lesions and the lesions can be reached by the endoscopes non-invasively in 1980's. Since 1990's, the interventional laser therapies adopted mainly were percutaneous laser angioplasty, laser treatments through laparoscope, thoracoscope, arthroscope, neuro-endoscope etc. Ultrasound guided percutaneous laser heat coagulation for small hepatic cancer revealed good results and ultrasound guided percutaneous PDT for advanced large liver cancer revealed unexpected results after five years follow-up. At present: There are more long-term follow-up patients in the clinical trial; more advanced commercial available lasers and new techniques are adopted. Since the popularization of scanning electron microscope, laser scanning confocal microscope, laser induced auto-fluorescence system, high sensitivity fluorescence microscopic imaging system etc. in the laboratories, the basic studies can be more advanced and some times, the sub-cellular level can be reached; ultra-structure histo-morphology and gene studies are involved. In dermatology, Q-switched Alexandrite laser and other Q-switched lasers are used mainly for the treatment of skin pigmentation and vascular diseases; pulsed dye laser, ultra-pulsed CO2 laser are used in resurfacing, facial acne scar, osmidrosis etc. For ophthalmology, excimer laser are used for myopia or hyperopia; argon green laser, krypton yellow laser are adopted in coagulation for retinal detachment and neovascularization etc. Lasers are often used for the canaliculoplasty in the lacrimal canal. Low level lasers had been used very often on the acupuncture points and for many chronic diseases. Intravascular low level laser irradiation adopting semiconductor lasers and He-Ne laser were reported to use for comatose patients, schizophrenia, vascular dementia, Alzeimer's disease and coronary disease. Reports from laboratory studies in the field of low level laser demonstrated the stimulation effect on the cells and immunology system; inhibitory effect on proliferation; it improved the biomedical data in hemorrheology; promoted the spinal motor nerve cell function, axonal regeneration; increased epidermal Langerhams cell to improve the antigen function, increased myocardial capillary permeability. Intra-cor","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116556659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：