首页 > 最新文献

The Internet Journal of Neurosurgery最新文献

英文 中文
Recurrent Esthesioneuroblastoma Presenting as an ACTH Paraneoplastic Syndrome 复发性感觉神经母细胞瘤表现为ACTH副肿瘤综合征
Pub Date : 2012-01-24 DOI: 10.5580/2b51
Shaun D. Rodgers, Y. Moshel, I. Mikolaenko, Alexander J. Gilbert, R. Babu
The authors report the case of a 51-year-old male that presented with hypertension and arm pain 5 years after combined transcranial and transfacial resection followed by radiotherapy for esthesioneuroblastoma. Laboratory studies revealed hypokalemia and elevated serum cortisol and ACTH levels. Brain magnetic resonance imaging (MRI) revealed a left-sided contrast-enhancing extra-axial dural-based lesion along the convexity. After resection of the convexity tumor, histological examination identified the lesion as recurrent esthesioneuroblastoma and serum ACTH and cortisol levels returned to near normal. Ectopic ACTH production from esthesioneuroblastoma is extremely rare and only six cases have been reported. This case report will describe the clinical presentation and pathology of recurrent esthesioneuroblastoma and review the literature.
作者报告了一例51岁的男性,在经颅和经面联合切除后放射治疗感觉神经母细胞瘤5年后出现高血压和手臂疼痛。实验室研究显示低钾血症和血清皮质醇和ACTH水平升高。脑磁共振成像(MRI)显示左侧轴外硬脑膜病变沿凸。切除凸性肿瘤后,经组织学检查确认为复发性神经母细胞瘤,血清ACTH和皮质醇水平恢复接近正常。异位促肾上腺皮质激素产生的感觉神经母细胞瘤是极为罕见的,只有6例报告。本病例报告将描述复发性感觉神经母细胞瘤的临床表现和病理,并复习文献。
{"title":"Recurrent Esthesioneuroblastoma Presenting as an ACTH Paraneoplastic Syndrome","authors":"Shaun D. Rodgers, Y. Moshel, I. Mikolaenko, Alexander J. Gilbert, R. Babu","doi":"10.5580/2b51","DOIUrl":"https://doi.org/10.5580/2b51","url":null,"abstract":"The authors report the case of a 51-year-old male that presented with hypertension and arm pain 5 years after combined transcranial and transfacial resection followed by radiotherapy for esthesioneuroblastoma. Laboratory studies revealed hypokalemia and elevated serum cortisol and ACTH levels. Brain magnetic resonance imaging (MRI) revealed a left-sided contrast-enhancing extra-axial dural-based lesion along the convexity. After resection of the convexity tumor, histological examination identified the lesion as recurrent esthesioneuroblastoma and serum ACTH and cortisol levels returned to near normal. Ectopic ACTH production from esthesioneuroblastoma is extremely rare and only six cases have been reported. This case report will describe the clinical presentation and pathology of recurrent esthesioneuroblastoma and review the literature.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122889685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Glioblastoma Multiforme In Elderly Population 老年人多形性胶质母细胞瘤
Pub Date : 2012-01-24 DOI: 10.5580/2b2b
R. Koul, A. Dubey, V. Torri, A. .. Kakumanu, Kunal Goyal
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain malignancy in the human race. The management of glioblastoma multiforme (GBM) in elderly patients is not well established in English literature. Despite treatment advances, survival of elderly GBM patients is usually < 12 months. Prognostically favorable elderly GBM patients should be included in prospective randomized combined-modality clinical trials. Quality-of-life issues should be strongly considered in this subset of patients. This is the review article looking into the pattern of presentation, treatment, and other related aspects in this subset of patients as management of glioblastoma multiforme (GBM) in elderly patients is not well established.
多形性胶质母细胞瘤(GBM)是人类最常见和侵袭性的原发性脑恶性肿瘤。老年多形性胶质母细胞瘤(GBM)的治疗在英国文献中尚未得到很好的确立。尽管治疗进展,但老年GBM患者的生存期通常小于12个月。预后良好的老年GBM患者应纳入前瞻性随机联合临床试验。在这类患者中应强烈考虑生活质量问题。由于老年患者多形性胶质母细胞瘤(GBM)的治疗尚不完善,这是一篇综述性文章,研究了这类患者的表现模式、治疗方法和其他相关方面。
{"title":"Glioblastoma Multiforme In Elderly Population","authors":"R. Koul, A. Dubey, V. Torri, A. .. Kakumanu, Kunal Goyal","doi":"10.5580/2b2b","DOIUrl":"https://doi.org/10.5580/2b2b","url":null,"abstract":"Glioblastoma multiforme (GBM) is the most common and aggressive primary brain malignancy in the human race. The management of glioblastoma multiforme (GBM) in elderly patients is not well established in English literature. Despite treatment advances, survival of elderly GBM patients is usually < 12 months. Prognostically favorable elderly GBM patients should be included in prospective randomized combined-modality clinical trials. Quality-of-life issues should be strongly considered in this subset of patients. This is the review article looking into the pattern of presentation, treatment, and other related aspects in this subset of patients as management of glioblastoma multiforme (GBM) in elderly patients is not well established.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126010070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Acute Paraplegia From Hemorrhagic Paraganglioma Of Filum Terminale: Case Report And Review Of Literature 出血性末梢副神经节瘤致急性截瘫1例报告及文献复习
Pub Date : 2012-01-24 DOI: 10.5580/2a87
Tracy S. Ma, Benjamin A. Rubin, B. Grobelny, D. Zagzag, M. Koslow, I. Mikolaenko, Robert E. Elliott
Paraganglioma (PGL) of the filum terminale is a rare tumor of extra-adrenal paraganglia. The reported cases of filum terminale and cauda equina PGLs often present with low-back pain and sciatica. While sensory or motor deficits and paraplegia may occur, the incidence is relatively low. We present a case of a 51-year old male with hemorrhagic paraganglioma of the filum terminale. He presented with acute paraplegia and was treated via emergent laminectomy, evacuation of hematoma, and resection of tumor. The patient had a significant but incomplete neurological recovery. The clinical, radiologic, and histopathological characteristics of the condition are described.
摘要副神经节瘤(PGL)是一种罕见的肾上腺外副神经节肿瘤。报道的病例终末丝和马尾pgl常表现为腰痛和坐骨神经痛。虽然可能发生感觉或运动缺陷和截瘫,但发病率相对较低。我们报告一例51岁男性患出血性副神经节瘤终末丝。他表现为急性截瘫,并通过紧急椎板切除术、血肿清除和肿瘤切除进行治疗。病人的神经系统有明显但不完全的恢复。临床,放射学和组织病理学特征的条件进行了描述。
{"title":"Acute Paraplegia From Hemorrhagic Paraganglioma Of Filum Terminale: Case Report And Review Of Literature","authors":"Tracy S. Ma, Benjamin A. Rubin, B. Grobelny, D. Zagzag, M. Koslow, I. Mikolaenko, Robert E. Elliott","doi":"10.5580/2a87","DOIUrl":"https://doi.org/10.5580/2a87","url":null,"abstract":"Paraganglioma (PGL) of the filum terminale is a rare tumor of extra-adrenal paraganglia. The reported cases of filum terminale and cauda equina PGLs often present with low-back pain and sciatica. While sensory or motor deficits and paraplegia may occur, the incidence is relatively low. We present a case of a 51-year old male with hemorrhagic paraganglioma of the filum terminale. He presented with acute paraplegia and was treated via emergent laminectomy, evacuation of hematoma, and resection of tumor. The patient had a significant but incomplete neurological recovery. The clinical, radiologic, and histopathological characteristics of the condition are described.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134365352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Editorial: A Butterfly Locked-In A Diving-Bell – Is Freedom Possible? 社论:一只被锁在潜水钟里的蝴蝶——自由可能吗?
Pub Date : 2012-01-24 DOI: 10.5580/2c4c
G. Matis, Danilo Silva, O. Chrysou, T. Birbilis
“I am locked in. I am as good as dead” [1]. Name: Jean-Dominique Bauby (Jean-Do)
“我被锁在里面了。我跟死了差不多”[1]。名字:让-多米尼克·鲍比(Jean-Do)
{"title":"Editorial: A Butterfly Locked-In A Diving-Bell – Is Freedom Possible?","authors":"G. Matis, Danilo Silva, O. Chrysou, T. Birbilis","doi":"10.5580/2c4c","DOIUrl":"https://doi.org/10.5580/2c4c","url":null,"abstract":"“I am locked in. I am as good as dead” [1]. Name: Jean-Dominique Bauby (Jean-Do)","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116078344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gunshot Injury To The Cervical Spine With Progressive Neurological Deterioration - A Case Report 颈椎枪伤伴进行性神经退化1例报告
Pub Date : 2012-01-24 DOI: 10.5580/2b2c
M. Salek, M. Mannan
A gunshot wound to the spine is a complex injury and is a major cause of spinal cord injury (SCI) globally among civilian populations, members of the military armed conflict personnel, or civilians injured in terrorists’ attacks. The bullet fragments may cause damage to the spinal cord directly and/or indirectly even without penetrating the spinal canal by concussive effects, heat, fractures or vascular injury. Regardless of injury level, new-onset or progressive neurologic deterioration is an indication for urgent decompression. In this article we report a case of a gunshot wound to the cervical spine with progressive neurological deterioration.
脊髓枪伤是一种复杂的损伤,是全球平民、军事武装冲突人员或恐怖袭击中受伤的平民脊髓损伤(SCI)的主要原因。子弹碎片可能直接和/或间接造成脊髓损伤,即使没有穿透椎管,也可能造成震荡效应、高温、骨折或血管损伤。无论损伤程度如何,新发或进行性神经系统恶化都是紧急减压的指征。在这篇文章中,我们报告了一个颈椎枪伤与进行性神经退化的病例。
{"title":"Gunshot Injury To The Cervical Spine With Progressive Neurological Deterioration - A Case Report","authors":"M. Salek, M. Mannan","doi":"10.5580/2b2c","DOIUrl":"https://doi.org/10.5580/2b2c","url":null,"abstract":"A gunshot wound to the spine is a complex injury and is a major cause of spinal cord injury (SCI) globally among civilian populations, members of the military armed conflict personnel, or civilians injured in terrorists’ attacks. The bullet fragments may cause damage to the spinal cord directly and/or indirectly even without penetrating the spinal canal by concussive effects, heat, fractures or vascular injury. Regardless of injury level, new-onset or progressive neurologic deterioration is an indication for urgent decompression. In this article we report a case of a gunshot wound to the cervical spine with progressive neurological deterioration.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130388830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Airbag Associated Bilateral Internal Carotid Artery Dissection with Hyperdense Middle Cerebral Artery Sign - A Case Report 气囊相关双侧颈内动脉夹层伴大脑中动脉高密度征1例报告
Pub Date : 2009-12-31 DOI: 10.5580/1a9f
A. Medhkour, Abdul Kader Tabbara
Although an uncommon injury, bilateral dissection of the internal carotid arteries can have devastating consequences. Awareness and diagnosis has risen since it was described in 1967 by Yamada et al. However, given the vague presentation and difficulty in diagnosis, it is important to identify all associated signs and symptoms. We present a previously unreported finding of bilateral hyperdense middle cerebral arteries in the absence of previously described contributing factors. Knowledge of this highly specific sign in patients involved in airbag-associated motor vehicle accidents can contribute to the early diagnosis and treatment of such patients.
虽然是一种罕见的损伤,但双侧颈内动脉夹层可能会造成毁灭性的后果。自1967年Yamada等人描述以来,人们对该病的认识和诊断有所提高。然而,由于表现模糊和诊断困难,重要的是要确定所有相关的体征和症状。我们提出了一个以前未报道的双侧大脑中动脉高密度的发现,在缺乏先前描述的因素。在涉及安全气囊相关机动车事故的患者中,了解这一高度特异性的体征有助于对此类患者进行早期诊断和治疗。
{"title":"Airbag Associated Bilateral Internal Carotid Artery Dissection with Hyperdense Middle Cerebral Artery Sign - A Case Report","authors":"A. Medhkour, Abdul Kader Tabbara","doi":"10.5580/1a9f","DOIUrl":"https://doi.org/10.5580/1a9f","url":null,"abstract":"Although an uncommon injury, bilateral dissection of the internal carotid arteries can have devastating consequences. Awareness and diagnosis has risen since it was described in 1967 by Yamada et al. However, given the vague presentation and difficulty in diagnosis, it is important to identify all associated signs and symptoms. We present a previously unreported finding of bilateral hyperdense middle cerebral arteries in the absence of previously described contributing factors. Knowledge of this highly specific sign in patients involved in airbag-associated motor vehicle accidents can contribute to the early diagnosis and treatment of such patients.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122055268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Minimally Invasive Option for Colloid Cysts Treatment. 胶体囊肿治疗的微创选择。
Pub Date : 2009-12-31 DOI: 10.5580/286b
V. A. Khachatrian, K. Samochernykh, D. Simonyan, A. V. Kim, Iu M Zabrodskaia, A. Khodorovskaya
In this work a group of authors is looking into perspective of minimal invasive procedures in treatment of colloid cysts. An extensive literature review is accompanied by a number of own observations and treatments of cranial colloid cysts by open and endoscopic methods.
在这项工作中,一组作者正在研究微创手术治疗胶体囊肿的前景。广泛的文献回顾是伴随着一些自己的观察和治疗颅胶质囊肿开放和内窥镜的方法。
{"title":"Minimally Invasive Option for Colloid Cysts Treatment.","authors":"V. A. Khachatrian, K. Samochernykh, D. Simonyan, A. V. Kim, Iu M Zabrodskaia, A. Khodorovskaya","doi":"10.5580/286b","DOIUrl":"https://doi.org/10.5580/286b","url":null,"abstract":"In this work a group of authors is looking into perspective of minimal invasive procedures in treatment of colloid cysts. An extensive literature review is accompanied by a number of own observations and treatments of cranial colloid cysts by open and endoscopic methods.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123374145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Management of Intraprocedural Adverse Events during coil embolization of cerebral aneurysms: A Clinical Case Series Review. 脑动脉瘤线圈栓塞术中不良事件的处理:临床病例系列回顾。
Pub Date : 2009-12-31 DOI: 10.5580/1b9d
A. Gordhan
The overall complication rate for endovascular coil embolization of cerebral aneurysms is 5% percent. This is an illustrative case series that describes management aspects and probable precipitants of adverse events during coil embolization and related imaging and clinical outcomes. Major intraprocedural intracranial adverse events during endovascular coil embolization of cerebral aneurysms can be divided into three categories. Thromboembolic, aneurysm or parent vessel perforations/ruptures and embolysate related. Clinical case examples with rescue intervention and outcomes are discussed within each category. 1) Thromboembolic (Case 1 and 2): This is the most frequent complication and cause of morbidity and mortality. Thromboembolic may occur consequent to failure of sustained and or sufficient systemic anticoagulation. Prevention of localized platelet and clotting cascade activation in the context of thrombogenic device introduction for coil embolization is vital in preventing partial or complete parent, branch or distal vessel occlusion. Embolic propagation of thrombus may arise from native vessel disease and or consequent to mechanical device manipulation during coil delivery and deployment, as well as with the use of adjuncts such as balloon assist. Frequent monitoring of ACT (Activated Clotting Time) values for systemic anticoagulation with Heparin to confirm twice the baseline value is the primary preventative method. Intraprocedural pharmacologic platelet thrombus dissolution with short and long acting Glycoprotein IIBIIIA inhibitors are effective when administered locally or systemically. Raising cerebral perfusion pressure may augment collateral flow with consequent reduction in the risk of ischemic sequelae. Intra arterial or peripheral venous administration of GPIIBIIIA inhibitors upon identification of intraluminal thrombus may prevent progression to complete vascular occlusion. Minimal thrombus formation at the coil/parent vessel interface is often observed. Eptifibatide has a shorter half life (2-4 hours) and is advantageous over Abciximab in ruptured aneurysm that potentially require post procedural placement of a ventriculostomy. A fluid bolus followed by appropriate pharmacologic induction of increased blood pressure allows for augmentation of collateral vasculature. Vessel caliber change or limitation of flow may be consequent to vasospasm. This can be addressed by localized intra arterial calcium channel blocker administration.
脑动脉瘤腔内线圈栓塞术的总并发症发生率为5%。这是一个说明性的病例系列,描述了在线圈栓塞期间的管理方面和不良事件的可能诱因,以及相关的影像学和临床结果。脑动脉瘤腔内线圈栓塞术中主要的术中颅内不良事件可分为三类。血栓栓塞、动脉瘤或母血管穿孔/破裂及栓塞相关。在每个类别中讨论具有抢救干预和结果的临床病例。1)血栓栓塞(病例1和2):这是最常见的并发症,也是发病率和死亡率的原因。由于持续和或充分的全身抗凝治疗失败,可能发生血栓栓塞。预防局部血小板和凝血级联激活在血栓形成装置引入线圈栓塞的背景下,是防止部分或完全的父母,分支或远端血管闭塞至关重要。血栓的栓塞性传播可能是由原生血管疾病引起的,也可能是由于在线圈输送和展开过程中机械装置的操作,以及使用辅助工具(如球囊辅助)造成的。经常监测ACT(活化凝血时间)值,以确认两倍的基线值的系统性抗凝肝素是主要的预防方法。术中应用短效和长效糖蛋白IIBIIIA抑制剂溶栓血小板,局部或全身均有效。提高脑灌注压可能增加侧支血流,从而降低缺血性后遗症的风险。在确定腔内血栓后,动脉或外周静脉给予GPIIBIIIA抑制剂可以防止进展为完全血管闭塞。通常在血管线圈/母血管界面处观察到最小的血栓形成。Eptifibatide的半衰期较短(2-4小时),在可能需要进行脑室造口术的破裂动脉瘤中比Abciximab更有优势。在适当的药理学诱导血压升高后服用液体丸,可以增强侧枝血管。血管痉挛可能导致血管口径改变或血流受限。这可以通过局部动脉内钙通道阻滞剂治疗。
{"title":"Management of Intraprocedural Adverse Events during coil embolization of cerebral aneurysms: A Clinical Case Series Review.","authors":"A. Gordhan","doi":"10.5580/1b9d","DOIUrl":"https://doi.org/10.5580/1b9d","url":null,"abstract":"The overall complication rate for endovascular coil embolization of cerebral aneurysms is 5% percent. This is an illustrative case series that describes management aspects and probable precipitants of adverse events during coil embolization and related imaging and clinical outcomes. Major intraprocedural intracranial adverse events during endovascular coil embolization of cerebral aneurysms can be divided into three categories. Thromboembolic, aneurysm or parent vessel perforations/ruptures and embolysate related. Clinical case examples with rescue intervention and outcomes are discussed within each category. 1) Thromboembolic (Case 1 and 2): This is the most frequent complication and cause of morbidity and mortality. Thromboembolic may occur consequent to failure of sustained and or sufficient systemic anticoagulation. Prevention of localized platelet and clotting cascade activation in the context of thrombogenic device introduction for coil embolization is vital in preventing partial or complete parent, branch or distal vessel occlusion. Embolic propagation of thrombus may arise from native vessel disease and or consequent to mechanical device manipulation during coil delivery and deployment, as well as with the use of adjuncts such as balloon assist. Frequent monitoring of ACT (Activated Clotting Time) values for systemic anticoagulation with Heparin to confirm twice the baseline value is the primary preventative method. Intraprocedural pharmacologic platelet thrombus dissolution with short and long acting Glycoprotein IIBIIIA inhibitors are effective when administered locally or systemically. Raising cerebral perfusion pressure may augment collateral flow with consequent reduction in the risk of ischemic sequelae. Intra arterial or peripheral venous administration of GPIIBIIIA inhibitors upon identification of intraluminal thrombus may prevent progression to complete vascular occlusion. Minimal thrombus formation at the coil/parent vessel interface is often observed. Eptifibatide has a shorter half life (2-4 hours) and is advantageous over Abciximab in ruptured aneurysm that potentially require post procedural placement of a ventriculostomy. A fluid bolus followed by appropriate pharmacologic induction of increased blood pressure allows for augmentation of collateral vasculature. Vessel caliber change or limitation of flow may be consequent to vasospasm. This can be addressed by localized intra arterial calcium channel blocker administration.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130475662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metachronous Pituitary Stalk And Cerebellar Hemangioblastomas In A Patient Without Von Hippel-Lindau Disease: Case Report And Review Of Literature 非希佩尔-林道病患者垂体柄异时性及小脑血管母细胞瘤1例报告及文献复习
Pub Date : 2009-12-31 DOI: 10.5580/2249
Adeolu L. Olasunkanmi, Robert E. Elliott, Kia Newman, I. Mikolaenko, D. Zagzag, J. Golfinos
Background: Hemangioblastomas (HBs) are benign neoplasms of the central nervous system (CNS) that account for 10–15% of posterior fossa tumors in adults. HBs most commonly arise in the cerebellum but also occur in the spinal cord and medulla. They occur sporadically as solitary lesions or in association with von Hippel-Lindau (VHL) disease and are usually multiple. HBs can arise in the supratentorial space (>100 reported cases) but only 16 cases of pituitary stalk HBs have been reported—87.5% of which occurred in the setting of VHL disease. Although multiple, metachronous and disseminated HBs can occur in the setting of VHL disease, there are no reported cases of focal, metachronous HBs in patients without this disease. Case Description: We report the case of a 61-year old man with no personal or family history of VHL disease who presented with a pituitary stalk HB 9 years after complete resection of a cerebellar HB. He underwent complete resection complicated by diabetes insipidis and visual field deterioration.Conclusion: The occurrence of HB at different times and in disparate locations within the CNS is not synonymous with the diagnosis of VHL disease. While diffuse dissemination has been reported following surgery, this is the first reported case of a focal metachronous HBs arising in a patient without VHL disease. Although its unusual location within the pituitary stalk complicated the diagnosis preoperatively, a second HB should be considered in the differential diagnosis and close follow-up may be warranted to identify such lesions prior to irreversible neurological deficits.
背景:血管母细胞瘤(HBs)是中枢神经系统(CNS)的良性肿瘤,占成人后窝肿瘤的10-15%。HBs最常见于小脑,但也发生在脊髓和髓质。它们偶尔发生为孤立病变或与von Hippel-Lindau (VHL)病有关,通常是多发的。HBs可发生在幕上间隙(>100例报道),但仅报道了16例垂体柄HBs,其中87.5%发生在VHL疾病的背景下。虽然在VHL疾病的背景下可能发生多发性、异时性和播散性乙肝,但没有这种疾病的患者中没有局灶性、异时性乙肝的报道。病例描述:我们报告一例61岁的男性,没有VHL疾病的个人或家族史,在小脑HB完全切除9年后出现垂体柄HB。患者因尿崩症及视野恶化行全切除术。结论:在中枢神经系统内不同时间和不同位置发生HB并不等同于VHL疾病的诊断。虽然有手术后弥漫性播散的报道,但这是第一例在无VHL疾病的患者中出现局灶性异时性HBs的报道。尽管其在垂体柄内的异常位置使术前诊断复杂化,但在鉴别诊断中应考虑第二例HB,并应密切随访,以便在出现不可逆的神经功能缺损之前识别此类病变。
{"title":"Metachronous Pituitary Stalk And Cerebellar Hemangioblastomas In A Patient Without Von Hippel-Lindau Disease: Case Report And Review Of Literature","authors":"Adeolu L. Olasunkanmi, Robert E. Elliott, Kia Newman, I. Mikolaenko, D. Zagzag, J. Golfinos","doi":"10.5580/2249","DOIUrl":"https://doi.org/10.5580/2249","url":null,"abstract":"Background: Hemangioblastomas (HBs) are benign neoplasms of the central nervous system (CNS) that account for 10–15% of posterior fossa tumors in adults. HBs most commonly arise in the cerebellum but also occur in the spinal cord and medulla. They occur sporadically as solitary lesions or in association with von Hippel-Lindau (VHL) disease and are usually multiple. HBs can arise in the supratentorial space (>100 reported cases) but only 16 cases of pituitary stalk HBs have been reported—87.5% of which occurred in the setting of VHL disease. Although multiple, metachronous and disseminated HBs can occur in the setting of VHL disease, there are no reported cases of focal, metachronous HBs in patients without this disease. Case Description: We report the case of a 61-year old man with no personal or family history of VHL disease who presented with a pituitary stalk HB 9 years after complete resection of a cerebellar HB. He underwent complete resection complicated by diabetes insipidis and visual field deterioration.Conclusion: The occurrence of HB at different times and in disparate locations within the CNS is not synonymous with the diagnosis of VHL disease. While diffuse dissemination has been reported following surgery, this is the first reported case of a focal metachronous HBs arising in a patient without VHL disease. Although its unusual location within the pituitary stalk complicated the diagnosis preoperatively, a second HB should be considered in the differential diagnosis and close follow-up may be warranted to identify such lesions prior to irreversible neurological deficits.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131824326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial Nerve Preservation In Vestibular Schwannoma Surgery- Anatomical And Functional Status 前庭神经鞘瘤手术中的面神经保存-解剖和功能状态
Pub Date : 2009-12-31 DOI: 10.5580/4ca
J. Dil, S. Dil, G. Manoharan, A. Raja
IntroductionSurgery for vestibular schwannoma taxes the surgeon’s skill to the hilt especially in removing the tumor completely and preserving the facial nerve.Aims To study the anatomical and functional status of the facial nerve in patients after vestibular schwannoma surgery and analyze the factors contributing to the outcome after surgery.Materials and methodsA retrospective analysis of all the case records of patients operated for Vestibular Schwannoma from 1980 to December 2007 in Kasturba Hospital Manipal was done which included their pre operative facial nerve function and post operative anatomical and functional status. The data was analyzed and conclusions drawn.Results210 patients who underwent surgery for vestibular schwannoma were included. In 111 patients(53%) preoperative facial nerve deficit was present and graded by House and Brackman grading. 207 out of 210 patients were operated by suboccipital retromastoid route. In 138 patients anatomical preservation of facial nerve was done, of which 120 patients underwent internal auditory meatus drilling. The rate of anatomical preservation has increased from 10% in the initial part of the study period to 100% in the latter part. Overall, 82.8% of the patients had a good functional outcome and 17.2% had a worse functional state than their preoperative status. We had operative mortality of 2.5%ConclusionsAbility to preserve the facial nerve improves with number of cases. Transmeatal drilling helped in identifying and protecting the facial nerve. Majority of patients in our series have presented as large tumors (69%) inspite of which good functional outcome was achieved.
前庭神经鞘瘤的手术对外科医生的技术要求很高,特别是在完全切除肿瘤和保留面神经方面。目的研究前庭神经鞘瘤术后患者面神经的解剖功能状况,分析影响术后预后的因素。材料与方法回顾性分析1980年至2007年12月在马尼帕市Kasturba医院行前庭神经鞘瘤手术的所有病例,包括术前面神经功能及术后解剖功能状况。对数据进行分析并得出结论。结果210例前庭神经鞘瘤患者接受手术治疗。111例患者(53%)术前存在面神经缺损,并按House和Brackman分级。210例患者中有207例经枕下乳突后路径手术。138例患者行面神经解剖保存术,其中120例行内耳道钻孔术。解剖保存率从研究初期的10%提高到后期的100%。总体而言,82.8%的患者功能预后良好,17.2%的患者功能状态较术前差。结论随着手术次数的增加,保留面神经的能力有所提高。经颅钻孔有助于识别和保护面神经。在我们的研究中,大多数患者表现为大肿瘤(69%),尽管功能预后良好。
{"title":"Facial Nerve Preservation In Vestibular Schwannoma Surgery- Anatomical And Functional Status","authors":"J. Dil, S. Dil, G. Manoharan, A. Raja","doi":"10.5580/4ca","DOIUrl":"https://doi.org/10.5580/4ca","url":null,"abstract":"IntroductionSurgery for vestibular schwannoma taxes the surgeon’s skill to the hilt especially in removing the tumor completely and preserving the facial nerve.Aims To study the anatomical and functional status of the facial nerve in patients after vestibular schwannoma surgery and analyze the factors contributing to the outcome after surgery.Materials and methodsA retrospective analysis of all the case records of patients operated for Vestibular Schwannoma from 1980 to December 2007 in Kasturba Hospital Manipal was done which included their pre operative facial nerve function and post operative anatomical and functional status. The data was analyzed and conclusions drawn.Results210 patients who underwent surgery for vestibular schwannoma were included. In 111 patients(53%) preoperative facial nerve deficit was present and graded by House and Brackman grading. 207 out of 210 patients were operated by suboccipital retromastoid route. In 138 patients anatomical preservation of facial nerve was done, of which 120 patients underwent internal auditory meatus drilling. The rate of anatomical preservation has increased from 10% in the initial part of the study period to 100% in the latter part. Overall, 82.8% of the patients had a good functional outcome and 17.2% had a worse functional state than their preoperative status. We had operative mortality of 2.5%ConclusionsAbility to preserve the facial nerve improves with number of cases. Transmeatal drilling helped in identifying and protecting the facial nerve. Majority of patients in our series have presented as large tumors (69%) inspite of which good functional outcome was achieved.","PeriodicalId":326784,"journal":{"name":"The Internet Journal of Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123434779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Internet Journal of Neurosurgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1