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The story of the African Association of Nephrology (AFRAN) 非洲肾病协会(AFRAN)的故事
Pub Date : 2017-03-15 DOI: 10.21804/20-1-1650
R. Barsoum
The African Association of Nephrology was founded in Cairo on 28 February 1987, during the ISN-sponsored “African Kidney and Electrolytes Conference”, being hosted and co-sponsored by the Egyptian Society of Nephrology. Twenty-five physicians interested in kidney disease, from 13 African countries, constituted the core assembly that selected a steering committee composed of five members, representing the five geographical zones in Africa. The committee proposed the name the African Association of Nephrology (AFRAN), approved its logo, defined its mission, and drafted its constitution. All were ratified at the first General Assembly meeting held in London in July of the same year. The steering committee was re-elected to continue as the Executive Committee for the first cycle and mandated to set the scene for future meetings, publications and programmes. AFRAN congresses have been held regularly ever since, triennially for three cycles, then biennially with a few exceptions. Scientific meetings including Continuing Medical Education activities and hands-on workshops addressing local kidney and electrolyte disorders, have been held in most African countries, with generous logistical and financial support by the International Society of Nephrology (ISN). The abstracts of the first congress were published in Kidney International. Meeting proceedings were usually distributed by hand, thanks to representatives of pharmaceutical companies in the various African countries. A quarterly newsletter was edited and published in the Sudan, upgraded to a journal (the African Journal of Nephrology) in 1997 and self-published from Egypt until the editorial office moved to South Africa in 2012. A registry of nephrologists and dialysis units in Africa was compiled and published from Algeria in 1989, then updated in the Sudan a few years later. More recently, an African Renal Registry was established, now hosted in South Africa. Numerous fellowships were offered by the better-off countries to their emerging neighbours, being sponsored by international organizations, mainly the ISN. Joint research has been conducted mainly through these fellowships. By its 10th birthday, AFRAN had encompassed all African countries, to become the official pan-African federation of national renal societies. The ISN initiatives for supporting the developing world, originally operated under the umbrella of the Commission for the Global Advancement of Nephrology (COMGAN), were instrumental in supporting AFRAN’s foundation and sustainability. Besides the ISN, AFRAN became affiliated to many other regional and all national societies of nephrology, which qualified it to serve as the principal liaison between African nephrology and that in the rest of the world.
非洲肾脏病协会于1987年2月28日在开罗成立,当时由ISN主办的“非洲肾脏和电解质会议”由埃及肾脏病学会主办和共同主办。来自13个非洲国家的25名对肾脏疾病感兴趣的医生组成了核心大会,选出了一个由五名成员组成的指导委员会,代表非洲的五个地理区域。该委员会提出了非洲肾脏病协会(AFRAN)的名称,批准了其标志,确定了其使命,并起草了其章程。同年7月在伦敦举行的第一次联合国大会批准了所有这些文书。指导委员会再次当选,继续担任第一个周期的执行委员会,并被授权为未来的会议、出版物和方案做好准备。自那以后,非洲区域网络大会一直定期举行,每三年举行一次,为期三个周期,然后每两年举行一次(少数例外)。在国际肾脏病学会(ISN)的慷慨后勤和财政支持下,大多数非洲国家都举行了科学会议,包括继续医学教育活动和解决当地肾脏和电解质疾病的实践研讨会。第一届大会的摘要发表在《肾脏国际》上。会议记录通常是手工分发的,感谢非洲各国制药公司的代表。在苏丹编辑和出版了一份季度通讯,1997年升级为期刊(《非洲肾病杂志》),并在埃及自行出版,直到2012年编辑部迁至南非。1989年,阿尔及利亚编制并出版了非洲肾脏病学家和透析单位的登记册,几年后在苏丹进行了更新。最近,设立了非洲肾脏登记处,目前设在南非。富裕国家向其新兴邻国提供了许多研究金,由国际组织,主要是ISN赞助。主要通过这些研究金进行了联合研究。到其10岁生日时,非洲肾脏学会已经涵盖了所有非洲国家,成为国家肾脏学会的官方泛非联合会。最初在全球肾脏病促进委员会(COMGAN)的保护伞下运作的ISN支持发展中国家的举措,有助于支持AFRAN的成立和可持续性。除了ISN,AFRAN还加入了许多其他地区和所有国家的肾脏病学会,这使它有资格成为非洲肾脏病学与世界其他地区肾脏病学之间的主要联络人。
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引用次数: 1
Abstracts of the South African Renal Congress 2016 (Cape Town, 9-11 September 2016) 2016南非肾脏大会(开普敦,2016年9月9-11日)摘要
Pub Date : 2017-01-01 DOI: 10.21807/19-1-1484
J. Jacobs
the following abstracts were presented as oral or poster presentations. Abstracts are published as received. those abstracts which were accepted for presentation at the Congress but were later withdrawn by the authors have been omitted.
下列摘要以口头或海报形式提出。摘要按收到的内容发布。那些被接受在大会上提交但后来被作者撤回的摘要已被省略。
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引用次数: 0
Editorial note 编辑注意
Pub Date : 2017-01-01 DOI: 10.21804/20-1-2452
M. R. Davids
Now that we have successfully migrated to our new online platform, AJN has taken the additional step of adopting a “publish-as-you-go” strategy. Articles will be published once they have been accepted and there will no longer be the usual wait until the next issue is published. New articles will be added throughout the year and will therefore be available to be read and cited much sooner. The latest articles which we are now publishing include a short review by Halperin on the assessment of the renal response in patients with potassium disorders. Halperin first gave us the well-known transtubular K+ gradient (TTKG) but in recent years has been recommending the use of the urine K+/creatinine ratio instead. In this article he explains the reasons for this change. Kapembwa et al. present their data on technique survival in patients on peritoneal dialysis (PD) at Tygerberg Hospital in Cape Town. Successfully maintaining patients on PD is especially important when a PD-first policy is being followed, as is the case at their centre. The issue of the access of rural patients with chronic kidney disease to healthcare is the topic of the paper by Singh et al., who report on referral patterns at a tertiary centre in Durban, South Africa. The paper by Camara et al., from the Free State province, South Africa, describes the outcomes of patients with acute kidney injury who needed continuous renal replacement therapy. In their cohort, patients with HIV infection were substantially younger and had a much worse outcome. Finally, the report by Makhoba et al. describes a case of osseous metaplasia in a renal allograft.
既然我们已经成功地迁移到新的在线平台,AJN已经采取了采用“随用随发”策略的额外步骤。文章一旦被接受就会发表,不再需要像往常一样等到下一期出版。新的文章将在全年添加,因此可以更快地阅读和引用。我们现在发表的最新文章包括Halperin对钾疾病患者肾脏反应评估的简短综述。Halperin首先给了我们众所周知的经短突K+梯度(TTKG),但近年来已经推荐使用尿K+/肌酐比值代替。在本文中,他解释了这一变化的原因。Kapembwa等人介绍了开普敦Tygerberg医院腹膜透析(PD)患者的技术生存率数据。当PD优先政策被遵循时,成功地维持PD患者是特别重要的,就像他们中心的情况一样。农村慢性肾病患者获得医疗保健的问题是Singh等人的论文主题,他们报告了南非德班一家三级中心的转诊模式。来自南非自由邦省的Camara等人的论文描述了需要持续肾脏替代治疗的急性肾损伤患者的结果。在他们的队列中,感染艾滋病毒的患者明显更年轻,结果也更糟糕。最后,Makhoba等人的报告描述了一例同种异体肾移植骨化生。
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引用次数: 0
Correction: Diagnostic and therapeutic aspects of recurrent renal stone disease 更正:复发性肾结石疾病的诊断和治疗方面
Pub Date : 2017-01-01 DOI: 10.21804/20-1-2556
A. Meyers, N. Whalley, M. Martins
In Table 3 of the original publication of this article [1], the citrate excretion in white subjects is given as 1.39(0.92), which is incorrect. The correct value is 2.39(0.92). Reference1. Meyers A, Whalley N, Martins M. Diagnostic and therapeutic aspects of recurrent renal stone disease. Afr J Nephrol. 1998; 2(1):12-17.
在这篇文章的原始出版物[1]的表3中,给出了白人受试者的柠檬酸排泄量为1.39(0.92),这是不正确的。正确值为2.39(0.92)。Reference1。李建军,李建军,李建军,等。复发性肾结石的诊断与治疗。[J] .尼弗罗尔。1998;2(1): 12 - 17。
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引用次数: 0
Editorial note 编辑注意
Pub Date : 2017-01-01 DOI: 10.21804/20-1-1649
Alain Assounga
As the official journal of the African Association of Nephrology (AFRAN), the African Journal of Nephrology (AJN) publishes research on kidney diseases by African and other researchers. AJN has reached a significant milestone in this first issue of Volume 20. This is the first issue which was prepared and published using our new web-based platform. We wish to take this opportunity to thank the editorial board, the reviewers and the authors for their role in the successful migration to the new platform. To mark this milestone, and to coincide with the March 2017 AFRAN/AFPNA Congress in Cameroon, we are delighted to publish a special article on the history of AFRAN by Professor Rashad Barsoum, one of the co-founders of AFRAN. Contributions to the success of AFRAN by the International Society of Nephrology, and by colleagues from Europe, America and Africa, are acknowledged. This is an illustrated story of our association told by its founding president, which is now immortalised in AJN. This issue also features an original article reporting on malignant kidney tumours in Port Harcourt, Nigeria. Nephroblastoma and renal cell carcinoma remain the leading kidney malignancies, as also reported worldwide. Finally, two interesting case reports conclude this issue: a case of IgG4-related nephropathy and a successful pregnancy in a patient on chronic haemodialysis.
作为非洲肾脏病学会(AFRAN)的官方期刊,《非洲肾脏病学杂志》(AJN)发表非洲和其他研究人员关于肾脏疾病的研究。AJN在第20卷的第一期达到了一个重要的里程碑。这是使用我们新的网络平台编写和出版的第一期。我们希望借此机会感谢编辑委员会、审稿人和作者在成功迁移到新平台中的作用。为了纪念这一里程碑,并与2017年3月在喀麦隆举行的AFRAN/AFPNA大会相一致,我们很高兴发表一篇由AFRAN联合创始人之一拉沙德·巴苏姆教授撰写的关于AFRAN历史的特别文章。国际肾脏病学会以及来自欧洲、美洲和非洲的同事对AFRAN的成功做出了贡献。这是一个插图的故事,我们的协会告诉它的创始主席,这是现在在AJN不朽。本期还刊载了一篇报道尼日利亚哈科特港恶性肾肿瘤的原创文章。肾母细胞瘤和肾细胞癌仍然是主要的肾脏恶性肿瘤,世界范围内也有报道。最后,两个有趣的病例报告总结了这个问题:一例igg4相关肾病和慢性血液透析患者的成功妊娠。
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引用次数: 0
Focal segmental glomerulosclerosis: challenges in definitions, pathogenesis and management 局灶节段性肾小球硬化:定义、发病机制和管理方面的挑战
Pub Date : 2017-01-01 DOI: 10.21807/20-1-2546
J. Feehally
Focal segmental glomerulosclerosis (FSGS) is a well-defined pattern of glomerular injury identifiable on renal biopsy using light microscopy. FSGS is not a single entity and much information is needed to make a proper evaluation in each subject with the condition to identify the cause, prognosticate, and inform treatment choices. Categories of information required include: clinical presentation, responsiveness to steroids, pathological subtype, genetic background, and evidence for other adaptive, viral, and toxic causes. Primary FSGS describes a cohort of conditions identified by exclusion of known contributory causes, but does not represent a single entity. Clinical manifestations and outcomes of FSGS vary widely; they include asymptomatic proteinuria, cases of spontaneous remission, steroid-sensitive nephrotic syndrome, and nephrotic syndrome resistant to immune modulating therapy progressing to end-stage renal disease with recurrence after transplantation. Although immune modulating therapy (based notably on corticosteroids and calcineurin inhibitors) are widely used in primary FSGS, robust evidence of their efficacy remains scant.
局灶节段性肾小球硬化(FSGS)是一种明确的肾小球损伤模式,可在肾活检中通过光学显微镜识别。FSGS不是一个单一的实体,需要大量的信息来对每个受试者进行适当的评估,以确定病因,预测预后,并告知治疗选择。所需信息的类别包括:临床表现、对类固醇的反应性、病理亚型、遗传背景以及其他适应性、病毒和毒性原因的证据。原发性FSGS描述了通过排除已知原因确定的一系列疾病,但不代表单一实体。FSGS的临床表现和结果差异很大;它们包括无症状蛋白尿、自发性缓解、类固醇敏感肾病综合征和对免疫调节治疗有抵抗力的肾病综合征,进展为终末期肾脏疾病,移植后复发。尽管免疫调节疗法(主要基于皮质类固醇和钙调磷酸酶抑制剂)广泛用于原发性FSGS,但其疗效的有力证据仍然很少。
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引用次数: 2
Nutrition, anaemia and erythropoietin therapy 营养,贫血和促红细胞生成素治疗
Pub Date : 2016-08-26 DOI: 10.21804/3-2-863
I. Macdougall
During the last decade, recombinant human erythropoietin has revolutionised the management of renal anaemia. It is highly effective in the vast majority of patients treated, causing enhanced erythropoiesis and a rise in haemoglobin concentration. This has resulted not only in amelioration of uraernic symptoms, but there has also been objective evidence of improved quality-of-life, exercise capacity, and cardiac function [I]. The most striking benefits seen have been progression of left ventricular hypertrophy which is known to account for much of the high cardiovascular morbidity and mortality seen in dialysis patients. and thus the arguments for correcting renal anaemia is now overwhelming. There is also an improvement in nutrition following erythropoietin therapy, over and above the improvement in appetite associated with correction of the anaemia.
在过去的十年中,重组人促红细胞生成素已经彻底改变了肾性贫血的管理。它在绝大多数接受治疗的患者中非常有效,引起红细胞生成增强和血红蛋白浓度升高。这不仅改善了尿毒症症状,也有客观证据表明生活质量、运动能力和心功能得到改善[1]。最显著的好处是左心室肥厚的进展,这是透析患者心血管疾病发病率和死亡率高的主要原因。因此,治疗肾性贫血的争论现在是压倒性的。在促红细胞生成素治疗后,营养方面也有改善,除了与贫血纠正相关的食欲改善之外。
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引用次数: 0
Encapsulating peritoneal sclerosis presenting with haemorrhagic ascites after transfer from peritoneal dialysis to haemodialysis 包膜性腹膜硬化,从腹膜透析转为血液透析后出现出血性腹水
Pub Date : 2015-10-01 DOI: 10.21804/18-1-727
M. Chothia, Davids
A patient with end-stage kidney disease due to chronic glomerulonephritis was initiated on continuous ambulatoryperitoneal dialysis. After three years he was transferred to haemodialysis following recurrent episodes of peritonitis. After the commencement of haemodialysis the patient developed progressive abdominal distension; paracentesisrevealed bloody ascites. Radiographic imaging revealed features of small bowel obstruction with bowel loops matted tothe posterior abdominal wall. A diagnosis of encapsulating peritoneal sclerosis was made. Treatment with prednisonewas initiated but the patients condition steadily worsened and he demised a year later due to severe malnutrition andsepsis.
一位因慢性肾小球肾炎而患有终末期肾脏疾病的患者开始了持续的动态腹膜透析。三年后,由于腹膜炎的反复发作,他被转移到血液透析。血液透析开始后,患者出现进行性腹胀;穿刺发现有血性腹水。影像学表现为小肠梗阻,肠袢缠结后腹壁。诊断为包膜性腹膜硬化。开始使用强的松治疗,但患者病情持续恶化,一年后因严重营养不良和败血症死亡。
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引用次数: 0
Editorial note 编辑注意
Pub Date : 2015-01-01 DOI: 10.21804/18-1-723
Alain Assounga
In this issue of the African Journal of Nephrology (AJN Vol 18, No 1) we publish original articles ranging from the prevalence of chronic kidney disease in an African population in general, to the role of HIV in kidney disease. An elegant study of fractionated heparin use in haemodialysis is also presented. Continuous ambulatory peritoneal dialysis is an important modality of renal replacement to be considered in Africa in view of its ease of operation. However, beware of potential complications including sclerosing peritonitis as reported in Cape Town (South Africa).As in the past, this issue covers a wide variety of topics with contributions from diverse authors from south to west and North Africa. On behalf of the editorial board, I wish to take this opportunity to thank all of the authors and reviewers who have contributed to this issue of the journal, as well as to the readers for their sustained interest in the African Journal of Nephrology.
在这一期的《非洲肾脏病杂志》(AJN第18卷第1期)中,我们发表了从非洲人口中慢性肾脏疾病的流行到艾滋病毒在肾脏疾病中的作用的原创文章。一个优雅的研究分离肝素使用在血液透析也提出。鉴于其易于操作,连续动态腹膜透析是非洲考虑的一种重要的肾脏替代方式。然而,要注意潜在的并发症,包括在开普敦(南非)报道的硬化性腹膜炎。与过去一样,这一期涵盖了从南部到西部和北非不同作者的广泛主题。我谨代表编辑委员会,借此机会感谢为本期杂志做出贡献的所有作者和审稿人,以及对《非洲肾脏病学杂志》持续关注的读者。
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引用次数: 0
Editorial note 编辑注意
Pub Date : 2014-01-01 DOI: 10.21804/17-1-737
Alain Assounga
In this issue of The African Journal of Nephrology (AJN Vol 17 No1) we publish an important editorial sponsored by the International Society of Nephrology.
在这一期的《非洲肾脏病杂志》(AJN第17卷第1期)中,我们发表了一篇由国际肾脏病学会赞助的重要社论。
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引用次数: 0
期刊
African Journal of Nephrology
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