M. Karimi, S. Nazari, Faramarz Shirani, Vahid Alivirdiloo, A. Siahposht-Khachaki, Sepehr Edalatkhah, Rama Khanian
{"title":"Neuroprotective effects of chloroquine on neurological scores, blood-brain barrier permeability, and brain edema after traumatic brain injury in male rats","authors":"M. Karimi, S. Nazari, Faramarz Shirani, Vahid Alivirdiloo, A. Siahposht-Khachaki, Sepehr Edalatkhah, Rama Khanian","doi":"10.18700/jnc.220052","DOIUrl":"https://doi.org/10.18700/jnc.220052","url":null,"abstract":"","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42017572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diffuse microbleeds in cerebral white matter have been
脑白质弥漫性微出血
{"title":"Massive microbleeds in posterior circulation territory in an immunocompromised patient with sepsis","authors":"Wonjae Sung, Young Seo Kim, Hee-Jin Kim","doi":"10.18700/jnc.220082","DOIUrl":"https://doi.org/10.18700/jnc.220082","url":null,"abstract":"Diffuse microbleeds in cerebral white matter have been","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45996911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of propofol-related infusion syndrome and discussion of POLG mitochondrial mutation: a case report","authors":"Brian Nguyen, S. Figueroa","doi":"10.18700/jnc.220071","DOIUrl":"https://doi.org/10.18700/jnc.220071","url":null,"abstract":",","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44880105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Euihyun Sung, Hyunkee Kim, Wonjae Sung, Jin-Ju Park
A 51-year-old male patient presented with a generalized tonic-clonic type seizure. He had a history of renal cell carcinoma and had received axitinib 2 weeks before this seizure event due to the unresponsiveness to the previous chemotherapeutics. He did not experience any neurologic symptoms previously. His vital rhythm showed elevated blood pressure and tachycardia. He became deeply drowsy soon after the seizure attack, with no definite later-alizing or localizing signs.
{"title":"Axitinib-induced posterior reversible encephalopathy syndrome in a patient with renal cell carcinoma","authors":"Euihyun Sung, Hyunkee Kim, Wonjae Sung, Jin-Ju Park","doi":"10.18700/jnc.220080","DOIUrl":"https://doi.org/10.18700/jnc.220080","url":null,"abstract":"A 51-year-old male patient presented with a generalized tonic-clonic type seizure. He had a history of renal cell carcinoma and had received axitinib 2 weeks before this seizure event due to the unresponsiveness to the previous chemotherapeutics. He did not experience any neurologic symptoms previously. His vital rhythm showed elevated blood pressure and tachycardia. He became deeply drowsy soon after the seizure attack, with no definite later-alizing or localizing signs.","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42448415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pupillary light reflex is a component of bedside neurological examinations in neurological intensive care units (neuroICUs). A quantitative pupillometer provides a non-invasive and objective pupil reactivity parameter clinically significant for changes in the pupillary light reflex in neuroICUs. This article reviews the physiology and importance of the pupillary light reflex and the parameters of quantitative pupillometers. Moreover, this review discusses the clinical applications of quantitative pupillometers for post-cardiac arrest prognostication and monitoring of elevated intracranial pressure and neurological worsening in stroke, seizures, and other neurological diseases in the neuroICU. Quantitative pupillometry is a routine part of neurological examinations and an important monitoring tool for neurological diseases in neuroICUs.
{"title":"Quantitative assessments of pupillary light reflexes in neurocritically ill patients","authors":"Tae Jung Kim","doi":"10.18700/jnc.220085","DOIUrl":"https://doi.org/10.18700/jnc.220085","url":null,"abstract":"The pupillary light reflex is a component of bedside neurological examinations in neurological intensive care units (neuroICUs). A quantitative pupillometer provides a non-invasive and objective pupil reactivity parameter clinically significant for changes in the pupillary light reflex in neuroICUs. This article reviews the physiology and importance of the pupillary light reflex and the parameters of quantitative pupillometers. Moreover, this review discusses the clinical applications of quantitative pupillometers for post-cardiac arrest prognostication and monitoring of elevated intracranial pressure and neurological worsening in stroke, seizures, and other neurological diseases in the neuroICU. Quantitative pupillometry is a routine part of neurological examinations and an important monitoring tool for neurological diseases in neuroICUs.","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42298513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypoxemia and critical illnesses such as sepsis and disseminated intravascular coagulopathy (DIC) are possible causes of massive microbleeds in the brain parenchyma [1]. We report a patient with human immunodeficiency virus (HIV) showing extensive cerebral microbleeds. A 59-year-old man presented with generalized tonic-clonic seizures. After admission, he was diagnosed with HIV infection while evaluating for pneumonia. Ten days after antiretroviral therapy (ART), DIC occurred as a result of pneumo-
{"title":"Diffuse cerebral microbleeds in a patient with HIV and disseminated intravascular coagulation","authors":"Wonjae Sung, Hyun-Seung Gwak, Young Seo Kim","doi":"10.18700/jnc.220083","DOIUrl":"https://doi.org/10.18700/jnc.220083","url":null,"abstract":"Hypoxemia and critical illnesses such as sepsis and disseminated intravascular coagulopathy (DIC) are possible causes of massive microbleeds in the brain parenchyma [1]. We report a patient with human immunodeficiency virus (HIV) showing extensive cerebral microbleeds. A 59-year-old man presented with generalized tonic-clonic seizures. After admission, he was diagnosed with HIV infection while evaluating for pneumonia. Ten days after antiretroviral therapy (ART), DIC occurred as a result of pneumo-","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45160684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Primiani, Khalil S. Husari, Rohan Mathur, R. Geocadin
Background: Fixed and dilated pupils (FDPs) have become synonymous with devastating neurological damage and brainstem injury commonly associated with mass effect and herniation. Infrequently, changes in pupillary light response have been described with seizures; however, the loss of pupillary response with documented Neurological Pupil index has not been well established in patients with seizures
{"title":"Fixed and dilated pupils by pupillometer in lateralized periodic discharges: a case report in the neurocritical care unit","authors":"C. Primiani, Khalil S. Husari, Rohan Mathur, R. Geocadin","doi":"10.18700/jnc.220066","DOIUrl":"https://doi.org/10.18700/jnc.220066","url":null,"abstract":"Background: Fixed and dilated pupils (FDPs) have become synonymous with devastating neurological damage and brainstem injury commonly associated with mass effect and herniation. Infrequently, changes in pupillary light response have been described with seizures; however, the loss of pupillary response with documented Neurological Pupil index has not been well established in patients with seizures","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44285313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Watchi, H. Quintard, P. Bijlenga, J. Pugin, T. R. Negro
,
，
{"title":"Negative-pressure helmet restores cerebral hemodynamic parameters in sinking skin flap syndrome: a case report","authors":"M. Watchi, H. Quintard, P. Bijlenga, J. Pugin, T. R. Negro","doi":"10.18700/jnc.220072","DOIUrl":"https://doi.org/10.18700/jnc.220072","url":null,"abstract":",","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42020054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brooke Barlow, Melissa L. Thompson Bastin, Aric Shadler, A. Cook
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{"title":"Association of chloride-rich fluids and medication diluents on the incidence of hyperchloremia and clinical consequences in aneurysmal subarachnoid hemorrhage","authors":"Brooke Barlow, Melissa L. Thompson Bastin, Aric Shadler, A. Cook","doi":"10.18700/jnc.220068","DOIUrl":"https://doi.org/10.18700/jnc.220068","url":null,"abstract":",","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42725943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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