Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2021.v11n3-223
Igor Trindade, Marise Pescador
Edwards’ syndrome is a severe genetic disease (chromosome 18 trisomy) that has a very restrict prognosis, resulting in premature death of the carrier. This study aims to report a case of survival of 12 years old girl diagnosed in the first months of life, her clinical evolution and the treatments performed by it. The multidisciplinary treatment performed by the adolescent since the first months of life shows the importance of this approach to improve the quality of life of patients with this syndrome.
{"title":"Teenager with Edwards’ syndrome: a rare case report","authors":"Igor Trindade, Marise Pescador","doi":"10.25060/residpediatr-2021.v11n3-223","DOIUrl":"https://doi.org/10.25060/residpediatr-2021.v11n3-223","url":null,"abstract":"Edwards’ syndrome is a severe genetic disease (chromosome 18 trisomy) that has a very restrict prognosis, resulting in premature death of the carrier. This study aims to report a case of survival of 12 years old girl diagnosed in the first months of life, her clinical evolution and the treatments performed by it. The multidisciplinary treatment performed by the adolescent since the first months of life shows the importance of this approach to improve the quality of life of patients with this syndrome.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121939397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2022.v12n4-583
D. Souza, Franciele Verzeletti, Mara Santos, Josiane Souza
Introduction: Rare diseases are chronic, progressive conditions with a low frequency of occurrence in the population. They can be divided into two groups: diseases of genetic origin and of non-genetic origin. Currently, molecular genetic tests are widely used to screen and diagnose patients with rare diseases. This study aims to describe the genetic/clinical profile of patients seen at the Rare Diseases Outpatient Clinic of a referral pediatric hospital in southern Brazil. Methodology: This retrospective descriptive quantitative study looked into data from paper and electronic medical charts of patients seen at the Rare Diseases Outpatient Clinic and genetic test results of included patients stored in the platform of the hospital’s Clinical Analysis Laboratory. Results and Discussion: The study included 553 patient medical charts. Prevalence of male patients and aged between zero and 11 years was greater. The most commonly reported symptoms were dysmorphisms and congenital malformations (12.5%), developmental delay (11.0%) and seizures (10.5%). Only 24.7% of the molecular genetic tests presented altered results. Alterations were more notably seen in genes PHKA2, G6PC, FBP1, and CTNS. The number of altered test results was lower than expected. The greater availability and popularization of these tests can be noticed by the increase in the number of tests ordered. Increased awareness about molecular genetic testing is very positive and may help healthcare teams improve patient quality of life.
{"title":"Clinical and Genetic Findings from a Rare Pediatric Diseases Outpatient Clinic in Curitiba, Brazil","authors":"D. Souza, Franciele Verzeletti, Mara Santos, Josiane Souza","doi":"10.25060/residpediatr-2022.v12n4-583","DOIUrl":"https://doi.org/10.25060/residpediatr-2022.v12n4-583","url":null,"abstract":"Introduction: Rare diseases are chronic, progressive conditions with a low frequency of occurrence in the population. They can be divided into two groups: diseases of genetic origin and of non-genetic origin. Currently, molecular genetic tests are widely used to screen and diagnose patients with rare diseases. This study aims to describe the genetic/clinical profile of patients seen at the Rare Diseases Outpatient Clinic of a referral pediatric hospital in southern Brazil. Methodology: This retrospective descriptive quantitative study looked into data from paper and electronic medical charts of patients seen at the Rare Diseases Outpatient Clinic and genetic test results of included patients stored in the platform of the hospital’s Clinical Analysis Laboratory. Results and Discussion: The study included 553 patient medical charts. Prevalence of male patients and aged between zero and 11 years was greater. The most commonly reported symptoms were dysmorphisms and congenital malformations (12.5%), developmental delay (11.0%) and seizures (10.5%). Only 24.7% of the molecular genetic tests presented altered results. Alterations were more notably seen in genes PHKA2, G6PC, FBP1, and CTNS. The number of altered test results was lower than expected. The greater availability and popularization of these tests can be noticed by the increase in the number of tests ordered. Increased awareness about molecular genetic testing is very positive and may help healthcare teams improve patient quality of life.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125966389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/RESIDPEDIATR-2020.V10N2-85
C. Rodrigues, Vitória Westarp, Adriana Natucci Hette, Tatiana Condo, Lorena Depieri, Carlos Gorios, R. Pereira, J. Armond
INTRODUCTION: Burns injuries are a significant health problem because they cause permanent or long lasting sequelae. OBJECTIVE: To characterize burn injuries, occurring among children and adolescents living in the city of Sao Paulo, and to identify the profile of pediatric patients treated for burn injuries. METHODS: This is a cross-sectional, quantitative, descriptive and retrospective study. A survey was carried out using data from the Information System for Violence and Accident Surveillance (SIVVA) of the Municipal Health Department of the city of Sao Paulo, where the reports of accidents against children and adolescents (0 to 19-years-old). RESULTS: During the study period, there were 416 burn injuries among children and adolescents living in the city of Sao Paulo. The main lesion diagnoses were: degree II burn (41.6%), the body region being more affected by wrist and hand. CONCLUSION: The results of this study showed that there was a higher frequency of burns among boys, preschoolers and the domestic environment. It emphasizes the importance of epidemiological researches in the subject because they can support preventive strategies, especially in the period of childhood and adolescence.
{"title":"Epidemiological profile of pediatric burn victims in the city of São Paulo","authors":"C. Rodrigues, Vitória Westarp, Adriana Natucci Hette, Tatiana Condo, Lorena Depieri, Carlos Gorios, R. Pereira, J. Armond","doi":"10.25060/RESIDPEDIATR-2020.V10N2-85","DOIUrl":"https://doi.org/10.25060/RESIDPEDIATR-2020.V10N2-85","url":null,"abstract":"INTRODUCTION: Burns injuries are a significant health problem because they cause permanent or long lasting sequelae. OBJECTIVE: To characterize burn injuries, occurring among children and adolescents living in the city of Sao Paulo, and to identify the profile of pediatric patients treated for burn injuries. METHODS: This is a cross-sectional, quantitative, descriptive and retrospective study. A survey was carried out using data from the Information System for Violence and Accident Surveillance (SIVVA) of the Municipal Health Department of the city of Sao Paulo, where the reports of accidents against children and adolescents (0 to 19-years-old). RESULTS: During the study period, there were 416 burn injuries among children and adolescents living in the city of Sao Paulo. The main lesion diagnoses were: degree II burn (41.6%), the body region being more affected by wrist and hand. CONCLUSION: The results of this study showed that there was a higher frequency of burns among boys, preschoolers and the domestic environment. It emphasizes the importance of epidemiological researches in the subject because they can support preventive strategies, especially in the period of childhood and adolescence.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124667319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/RESIDPEDIATR-2021.V11N1-504
residpediatr .v n . residpediatr .v n
A recent study from the UK, has described an apparent increase in new type 1 diabetes (T1DM) onset in children during COVID-19 pandemic. Both Brazil and USA (including our area of Houston, TX) have recently suffered from a sudden surge of this infection and we have noticed an association between the infection and 2 new cases of pediatric diabetes presenting in diabetes ketoacidosis. This association may become important in the future if the epidemiological data of T1DM shows an increased trend post the COVID-19 infection. It is also important to note that one patient was asymptomatic, this may be important to consider early screening and diagnosis to prevent the spread of infection.
{"title":"Pediatric type 1 diabetes mellitus and COVID-19 infection: is there an association?","authors":"residpediatr .v n . residpediatr .v n","doi":"10.25060/RESIDPEDIATR-2021.V11N1-504","DOIUrl":"https://doi.org/10.25060/RESIDPEDIATR-2021.V11N1-504","url":null,"abstract":"A recent study from the UK, has described an apparent increase in new type 1 diabetes (T1DM) onset in children during COVID-19 pandemic. Both Brazil and USA (including our area of Houston, TX) have recently suffered from a sudden surge of this infection and we have noticed an association between the infection and 2 new cases of pediatric diabetes presenting in diabetes ketoacidosis. This association may become important in the future if the epidemiological data of T1DM shows an increased trend post the COVID-19 infection. It is also important to note that one patient was asymptomatic, this may be important to consider early screening and diagnosis to prevent the spread of infection.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129360549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/RESIDPEDIATR-2020.V10N2-90
V. Rosa, G. Kuzma, L. Hornung, M. Bandeira
OBJECTIVE: Benign acute childhood myositis is characterized by acute musculoskeletal involvement leading to transient limitations on deambulation followed by a viral illness. Our study objective to evaluate clinical and laboratory features of patients in a pediatric emergency department. METHODOS: We conducted a prospective study in patients with symptoms and laboratory findings compatible with viral myositis in the period of August 2017 to August 2018. RESULTS: We assessed 20 patients in the period of twelve months. The mean age was 8,25 years. Of these, 83,3% had infectious symptoms in the week before the musculoskeletal involvement. By the time of the diagnosis, the symptoms were: calf pain, reluctance to walk, gait abnormality, diffuse myalgia and calf weakness. The most relevant laboratory finding was the elevation of CPK (mean 3359,556U/L) level, followed by AST (mean 131U/L) and ALT (mean 64,66U/L) elevation. The mean time for symptom relief was 3 days and in 7 days all exams were normal. CONCLUSION: Though the exact incidence of this condition remains undetermined, the lower extremity pain and the gait abnormality is of concern of both parents and health care providers. We emphasize the importance of knowing this condition to avoid unnecessary exams and the delay in the diagnosis of severe conditions.
{"title":"Acute benign myositis of childhood: Results of a prospective study performed in a pediatric emergency department","authors":"V. Rosa, G. Kuzma, L. Hornung, M. Bandeira","doi":"10.25060/RESIDPEDIATR-2020.V10N2-90","DOIUrl":"https://doi.org/10.25060/RESIDPEDIATR-2020.V10N2-90","url":null,"abstract":"OBJECTIVE: Benign acute childhood myositis is characterized by acute musculoskeletal involvement leading to transient limitations on deambulation followed by a viral illness. Our study objective to evaluate clinical and laboratory features of patients in a pediatric emergency department. METHODOS: We conducted a prospective study in patients with symptoms and laboratory findings compatible with viral myositis in the period of August 2017 to August 2018. RESULTS: We assessed 20 patients in the period of twelve months. The mean age was 8,25 years. Of these, 83,3% had infectious symptoms in the week before the musculoskeletal involvement. By the time of the diagnosis, the symptoms were: calf pain, reluctance to walk, gait abnormality, diffuse myalgia and calf weakness. The most relevant laboratory finding was the elevation of CPK (mean 3359,556U/L) level, followed by AST (mean 131U/L) and ALT (mean 64,66U/L) elevation. The mean time for symptom relief was 3 days and in 7 days all exams were normal. CONCLUSION: Though the exact incidence of this condition remains undetermined, the lower extremity pain and the gait abnormality is of concern of both parents and health care providers. We emphasize the importance of knowing this condition to avoid unnecessary exams and the delay in the diagnosis of severe conditions.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"205 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122344010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2022.v12n3-463
P. Ruiz, N. Santiago, Mariana Aquino, S. Batista
OBJECTIVES: Define the prevalence of exclusive breastfeeding among patients that received discharge in breastfeeding, exclusive or complementing with formula, 15 days after discharge from the neonatal unit and the related factors. METHODS: Observational, descriptive, prospective study, including newborns hospitalized in the Neonatal Unit who were discharged in breastfeeding, exclusive or mixed with formula, during the period from May to July, 2019. Fifteen days after hospital discharge, it was made a phone contact to the mother asking about the type of feeding in that moment. RESULTS: The prevalence of exclusive breastfeeding 15 days after hospital discharge was 62.3%. Birthweight and gestational age were significantly higher and the length of stay was smaller in the group being exclusively breastfed 15 days after discharge (p<0.05). There was a positive correlation between exclusive breastfeeding by hospital discharge and exclusive breastfeeding 15 days after discharge (p<0.05). CONCLUSION: Initiating and maintaining breastfeeding for newborns who need hospitalization for healthcare is a challenge and requires all the efforts in terms of structure and process. Factors such as birthweight, gestational age and length of hospital stay have influence on the prevalence of breastfeeding after discharge. Exclusive breastfeeding by the hospital discharge has favored breastfeeding 15 days after discharge.
{"title":"Prevalência de aleitamento materno exclusivo após internação em unidade de cuidados neonatais","authors":"P. Ruiz, N. Santiago, Mariana Aquino, S. Batista","doi":"10.25060/residpediatr-2022.v12n3-463","DOIUrl":"https://doi.org/10.25060/residpediatr-2022.v12n3-463","url":null,"abstract":"OBJECTIVES: Define the prevalence of exclusive breastfeeding among patients that received discharge in breastfeeding, exclusive or complementing with formula, 15 days after discharge from the neonatal unit and the related factors. METHODS: Observational, descriptive, prospective study, including newborns hospitalized in the Neonatal Unit who were discharged in breastfeeding, exclusive or mixed with formula, during the period from May to July, 2019. Fifteen days after hospital discharge, it was made a phone contact to the mother asking about the type of feeding in that moment. RESULTS: The prevalence of exclusive breastfeeding 15 days after hospital discharge was 62.3%. Birthweight and gestational age were significantly higher and the length of stay was smaller in the group being exclusively breastfed 15 days after discharge (p<0.05). There was a positive correlation between exclusive breastfeeding by hospital discharge and exclusive breastfeeding 15 days after discharge (p<0.05). CONCLUSION: Initiating and maintaining breastfeeding for newborns who need hospitalization for healthcare is a challenge and requires all the efforts in terms of structure and process. Factors such as birthweight, gestational age and length of hospital stay have influence on the prevalence of breastfeeding after discharge. Exclusive breastfeeding by the hospital discharge has favored breastfeeding 15 days after discharge.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130199592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2022.v12n2-317
R. Oliveira, A. Nau, Rafaela Assmann, M. Bandeira
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is a systemic inflammatory condition and the most common chronic rheumatological disease in childhood. Among complications, patients may have osteoporosis induced by treatment with glucocorticoids or the evolution of the disease. Another rare complication is the involvement of laryngeal cartilage, which may present with stridor or respiratory failure. The purpose of this report is to present a case of JIA with osteoporosis and laryngeal manifestations. CASE REPORT: Female, 15 years old, diagnosed with JIA 12 years ago with irregular treatment that evolved with severe and limiting disease. The patient had stridor and dyspnoea. Laryngoscopy showed involvement of arytenoid cartilage requiring tracheostomy. In addition, the patient was diagnosed with osteoporosis and bilateral coxarthrosis, requiring bilateral total hip arthroplasty.
{"title":"Osteoporosis and laryngeal involvement secondary to juvenile idiopathic arthritis: case report","authors":"R. Oliveira, A. Nau, Rafaela Assmann, M. Bandeira","doi":"10.25060/residpediatr-2022.v12n2-317","DOIUrl":"https://doi.org/10.25060/residpediatr-2022.v12n2-317","url":null,"abstract":"OBJECTIVE: Juvenile idiopathic arthritis (JIA) is a systemic inflammatory condition and the most common chronic rheumatological disease in childhood. Among complications, patients may have osteoporosis induced by treatment with glucocorticoids or the evolution of the disease. Another rare complication is the involvement of laryngeal cartilage, which may present with stridor or respiratory failure. The purpose of this report is to present a case of JIA with osteoporosis and laryngeal manifestations. CASE REPORT: Female, 15 years old, diagnosed with JIA 12 years ago with irregular treatment that evolved with severe and limiting disease. The patient had stridor and dyspnoea. Laryngoscopy showed involvement of arytenoid cartilage requiring tracheostomy. In addition, the patient was diagnosed with osteoporosis and bilateral coxarthrosis, requiring bilateral total hip arthroplasty.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130206482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2022.v12n4-795
Rachel Silveira, Ana Carla Rocha, Arthur O. Vale, D. Sena, R. Chaves
OBJECTIVES: To describe the main impacts of physical inactivity, increased screen time, and violence against children on the psychological and cognitive development supported by changes in habits during the COVID-19 pandemic. METHODS: A narrative review of the literature with publications from 2012 to 2021 was conducted based on data from the U.S. National Library of Medicine (PubMed) and from the Scientific Electronic Library Online (SciELO). The following keywords were used: “Child Behavior”; “Screen time”; “Covid-19”; “Sedentary behavior” e “Domestic Violence”. RESULTS: An intensification of the use of electronic devices, increased rates of child abuse and children’s physical inactivity during the COVID-19 pandemic was observed. CONCLUSION: Social isolation due to the COVID-19 pandemic resulted in the aggravation of pre-existing problems in children, such as increased screen time, physical inactivity and violence against children.
{"title":"The impacts of the COVID-19 pandemic on child and adolescent health: A literature review","authors":"Rachel Silveira, Ana Carla Rocha, Arthur O. Vale, D. Sena, R. Chaves","doi":"10.25060/residpediatr-2022.v12n4-795","DOIUrl":"https://doi.org/10.25060/residpediatr-2022.v12n4-795","url":null,"abstract":"OBJECTIVES: To describe the main impacts of physical inactivity, increased screen time, and violence against children on the psychological and cognitive development supported by changes in habits during the COVID-19 pandemic. METHODS: A narrative review of the literature with publications from 2012 to 2021 was conducted based on data from the U.S. National Library of Medicine (PubMed) and from the Scientific Electronic Library Online (SciELO). The following keywords were used: “Child Behavior”; “Screen time”; “Covid-19”; “Sedentary behavior” e “Domestic Violence”. RESULTS: An intensification of the use of electronic devices, increased rates of child abuse and children’s physical inactivity during the COVID-19 pandemic was observed. CONCLUSION: Social isolation due to the COVID-19 pandemic resulted in the aggravation of pre-existing problems in children, such as increased screen time, physical inactivity and violence against children.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"31 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123737313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2020.v10n2-355
A. Venerabile
OBJECTIVES: Highlight the asthma situation in this pandemic. Describe the safety aspects of patients and health professionals. Discuss its severity, control, risk factors, therapeutic management of chronic disease and its exacerbations. METHODS: Data were collected from the scientific literature on the topic asthma in the context of the COVID-19 pandemic. A search was performed in PubMed databases, using the descriptors: asthma, coronavirus infections, pandemics, risk factors, drug therapy and spirometry. RESULTS: Asthma has not been identified as a significant risk factor for severe COVID-19 disease, perhaps due to the lower expression of angiotensin-converting enzyme receptors in atopic asthma. Groups were identified, among severe asthmatics, with greater expression of these receptors. CONCLUSIONS: Nebulizers should be avoided, spacers should not be shared and spirometry or peak expiratory flow measurement is not recommended. All asthmatics should be maintained on inhaled corticosteroids. Short-acting beta2-agonist only treatment is not recommended from the age of 12. As-needed low dose inhaled corticosteroid with formoterol is the prefered reliever for this age group and can be offered together on the same device. From 6 to 11-years-old, reliever medication should preferably be short-acting beta2-agonists, associated with low dose inhaled corticosteroids and applied in separate devices. In severe asthma, tiotropium should precede the indication of the immunobiological and this, when in use, should not be interrupted.
{"title":"Asthma and COVID-19","authors":"A. Venerabile","doi":"10.25060/residpediatr-2020.v10n2-355","DOIUrl":"https://doi.org/10.25060/residpediatr-2020.v10n2-355","url":null,"abstract":"OBJECTIVES: Highlight the asthma situation in this pandemic. Describe the safety aspects of patients and health professionals. Discuss its severity, control, risk factors, therapeutic management of chronic disease and its exacerbations. METHODS: Data were collected from the scientific literature on the topic asthma in the context of the COVID-19 pandemic. A search was performed in PubMed databases, using the descriptors: asthma, coronavirus infections, pandemics, risk factors, drug therapy and spirometry. RESULTS: Asthma has not been identified as a significant risk factor for severe COVID-19 disease, perhaps due to the lower expression of angiotensin-converting enzyme receptors in atopic asthma. Groups were identified, among severe asthmatics, with greater expression of these receptors. CONCLUSIONS: Nebulizers should be avoided, spacers should not be shared and spirometry or peak expiratory flow measurement is not recommended. All asthmatics should be maintained on inhaled corticosteroids. Short-acting beta2-agonist only treatment is not recommended from the age of 12. As-needed low dose inhaled corticosteroid with formoterol is the prefered reliever for this age group and can be offered together on the same device. From 6 to 11-years-old, reliever medication should preferably be short-acting beta2-agonists, associated with low dose inhaled corticosteroids and applied in separate devices. In severe asthma, tiotropium should precede the indication of the immunobiological and this, when in use, should not be interrupted.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123696786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.25060/residpediatr-2023-745
C. Batista, B. Santos, G. Santos, Giulia Ciuccio, Vicente Gerardi Filho
Vesicoureteral reflux (VUR) is characterized by retrograde urine flow, caused by impaired occlusion of the intramural portion of the ureter by contraction of the detrusor muscle during urination or secondary to altered bladder dynamics, ureteral obstruction and neuromuscular diseases, such as Phelans syndrome - McDermid. This syndrome is a rare and underreported disease, resulting from the formation of chromosome 22 in a ring and has VUR as its main urological manifestation. The objective of this study is to alert the medical community about one of the differential diagnoses in the VUR etiology, based on the case of a female patient, 4 years and 2 months old, referred to the Pediatric Surgery service of the Mário Covas State Hospital with recurrent infection of urinary tract associated with impaired renal function and bilateral VUR evidenced on cystourethrography. During investigation, the phenotypic findings encouraged the performance of a karyotype that confirmed the alterations found in PhelanMcDermid syndrome. VUR early diagnosis was essential to establish the appropriate therapy, which involved clinical and surgical approaches aimed at improving quality of life, preserving the renal parenchyma and preventing further future complications.
{"title":"ASSOCIATION BETWEEN VESICURETERAL REFLUX AND CHROMOSOME 22 RING ANOMALY - CASE REPORT","authors":"C. Batista, B. Santos, G. Santos, Giulia Ciuccio, Vicente Gerardi Filho","doi":"10.25060/residpediatr-2023-745","DOIUrl":"https://doi.org/10.25060/residpediatr-2023-745","url":null,"abstract":"Vesicoureteral reflux (VUR) is characterized by retrograde urine flow, caused by impaired occlusion of the intramural portion of the ureter by contraction of the detrusor muscle during urination or secondary to altered bladder dynamics, ureteral obstruction and neuromuscular diseases, such as Phelans syndrome - McDermid. This syndrome is a rare and underreported disease, resulting from the formation of chromosome 22 in a ring and has VUR as its main urological manifestation. The objective of this study is to alert the medical community about one of the differential diagnoses in the VUR etiology, based on the case of a female patient, 4 years and 2 months old, referred to the Pediatric Surgery service of the Mário Covas State Hospital with recurrent infection of urinary tract associated with impaired renal function and bilateral VUR evidenced on cystourethrography. During investigation, the phenotypic findings encouraged the performance of a karyotype that confirmed the alterations found in PhelanMcDermid syndrome. VUR early diagnosis was essential to establish the appropriate therapy, which involved clinical and surgical approaches aimed at improving quality of life, preserving the renal parenchyma and preventing further future complications.","PeriodicalId":338092,"journal":{"name":"Residência Pediátrica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130650734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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