Namık Kemal Tıp Dergisi最新文献

{"title":"Preoperative Low Serum Magnesium Level is a Significant Predictive Factor for Postoperative Hypomagnesemia in Patients Who Underwent Parathyroidectomy for Primary Hyperparathyroidism","authors":"Serhat Meric, N. Hacım","doi":"10.4274/nkmj.galenos.2021.42714","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.42714","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129223034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting the Survival Rate of Patients with Pulmonary Thromboembolism","authors":"Hakan Çelikhisar, Gulay Ilkhan Dasdemir","doi":"10.4274/nkmj.galenos.2021.80299","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.80299","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116745751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Post-transplant Cyclophosphamide Containing Immunosuppressive Regimen with Standard Immunosuppressive Regimen in Allogeneic Stem Cell Transplantation from Matched Sibling Donor","authors":"Osman Kara, T. Elibol","doi":"10.4274/nkmj.galenos.2021.91300","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.91300","url":null,"abstract":"Address for Correspondence: Tayfun ELİBOL MD, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, Clinic of Hematology, İstanbul, Turkey Phone: +90 539 656 29 42 E-mail: tayfunelibol@gmail.com ORCID ID: orcid.org/0000-0001-8738-5246 Received: 09.05.2021 Accepted: 05.08.2021 ÖZ Amaç: Allojenik kök hücre nakli (AKHN), birçok hematolojik malignite için, graft-versus-host hastalığı (GVHH) gibi bazı hayatı tehdit edici risklerine rağmen halen tek küratif tedavi yöntemidir. GVHH post-transplant siklofosfamid uygulamasıyla birlikte haploidentik kök hücre nakli yapılan hastalarda dahi kontrol altına alınabilmektedir. Çalışmamızın amacı da tam uyumlu kardeş donörden yapılan nakillerde post-transplant siklofosfamid kullanımının GVHH üzerine olan etkinliğini standart immünosüpresif tedaviyle karşılaştırmaktır. Gereç ve Yöntem: Yüksek riskli hematolojik malignite tanısı olup tam uyumlu kardeş donörden AKHN yapılan hastalar çalışmaya alındı. Posttransplant siklofosfamid tedavisi alan hastalar, immünosüpresif tedavi olarak ayrıca takrolimus ve mikofenolat mofetil aldı; diğer kolda ise hastalar metotreksat ve siklosporin ile standart immünosüpresif tedavi aldı. Çalışmanın primer sonlanım noktası şiddetli akut GVHH gelişimi sıklığı olarak belirlendi. ABSTRACT Aim: Allogeneic stem cell transplantation (ASCT) is the only treatment that can cure most of malignant hematological diseases with the risk of some serious complications such as graft-versus-host disease (GVHD). GVHD can be got under control with post-transplant cyclophosphamide even in patients with haploidentical stem cell transplants. Here, we aimed to compare the effectiveness of post-transplant cyclophosphamide on GVHD with standard immunosuppressive therapy. Materials and Methods: Patients with high-risk hematologic malignancies, who received ASCT from human leukocyte antigen-matched sibling donors, were studied. Patients in the post-transplant cyclophosphamide group also used tacrolimus and mycophenolate mofetil; on the other side, standard immunosuppressive treatment with cyclosporine and methotrexate was used. The primary endpoint of the study was to compare the severe acute GVHD rate between the groups. Results: A total of 40 patients were included in the study. While severe (grade 3-4) GVHD was seen in three patients in the methotrexate-cyclosporin group, it was not seen in any patient in the post-transplant cyclophosphamide group. Also, 10th-month progress-free survival and overall survivals were 78.8% and 93.3% vs 56% and 72% in the post-transplant cyclophosphamide group and methotrexate-cyclosporin group, respectively. Conclusion: Cyclophosphamide can be the cheapest, most applicable, and clinically effective treatment in GVHD prophylaxis.","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123758541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy and Reliability Study of the Simplified Nutritional Assessment Questionnaire (SNAQ) in Turkish Patients in Nutritional Evaluation","authors":"Kevser KUTLU TATAR, R. Sivritepe, Sema Uçak Basat","doi":"10.4274/nkmj.galenos.2021.92486","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.92486","url":null,"abstract":"Address for Correspondence: Rıdvan SİVRİTEPE MD, İstanbul Medipol University Faculty of Medicine, Department of Internal Medicine, İstanbul, Turkey Phone: +90 545 260 59 57 E-mail: dr.ridvansivritepe@gmail.com ORCID ID: orcid.org/0000-0003-0547-1883 Received: 11.02.2021 Accepted: 21.05.2021 ÖZ Amaç: Bu çalışmada oldukça basit ve kolay uygulanabilir bir nütrisyonel değerlendirme testi olan Basitleştirilmiş Beslenme ve İştah Anketi (SNAQ) testinin Türk popülasyonunda doğruluk ve güvenilirliği araştırıldı. Gereç ve Yöntem: Çalışma tek merkezli prospektif bir çalışma olarak tasarlandı. İç hastalıkları kliniğimize yatan 65 yaş üstü hastalar çalışmaya dahil edildi. SNAQ testinin Türkçe formu bulunmadığından yeminli tercüman tarafından İngilizce’den Türkçe’ye çevrildi ve sağlamasını yapmak üzere Türkçe’den İngilizce’ye çevirisi yapıldı. Çalışmanın örneklem genişliği 200 hasta olarak tespit edildi. Çalışmaya alınan her hastada Mini Beslenme Değerlendirmesi, Nütrisyonel Risk Tarama Aracı-2002 ve SNAQ nütrisyonel değerlendirme testleri uygulandı. Bulgular: Araştırmaya katılanların %51’i kadın, %49’u erkekti. Katılımcıların %55,5’i 65 ile 74, %23,5’i 75 ile 84 yaş aralığında ve %21’i ise 85 yaş ve üzerindeydi. Basitleştirilmiş beslenme ve iştah anketinin güvenilirlik katsayısının 0,86 olduğu görülmektedir. Bu değerin literatürde öngörülen 0,60 alt limit kriterini sağlamakta olduğu görüldü. Sonuç: Türk geriatrik hasta popülasyonunun nütrisyonel açıdan değerlendirilmesinde Türkçe SNAQ doğruluk ve güvenilirliği ispatlanmıştır. Anahtar Kelimeler: NRS-2002, MNA, SNAQ, Türkçe validasyon, malnütrisyon ABSTRACT Aim: This study aims to reveal the accuracy and reliability of Simplified Nutritional Assessment Questionnaire (SNAQ), which is a test relatively simple and easy to apply, in the Turkish population. Materials and Methods: This study was planned as monocentric and prospective. Patients who were hospitalized in the internal medicine ward and over 65 years old participated in the study. Since there is no SNAQ test in Turkish, its English version was translated into Turkish by a certified translator, and then translated back into English again for verification. The sample size of the study was determined as 200 patients. For each patient included in the study, Mini Nutritional Assessment, Nutritional Risk Screening-2002 and SNAQ tests were applied. Results: Participants consisted of 51% female and 49% male. 55.5% were at the age between 65 and 74 years, 23.5% were between 75 and 84 years, and 21% were over 85 years old. The reliability coefficient of the SNAQ test was found as 0.86. This value satisfied the lower limit criterion of 0.60 proposed in the literature. Conclusion: Turkish SNAQ was validated and proved to be reliable for the nutritional evaluation of the geriatric Turkish patient population.","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123211876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mid-long Term Results of Dorsal Approach and Temporary Fixation Procedure in Overlooked Perilunate Carpal Dislocation","authors":"M. Ü. Çetin, Abdulkadir Sarı, F. Fidan, Abdulkadir POLAT, I. B. Özçelik","doi":"10.4274/nkmj.galenos.2021.43433","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.43433","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122898006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Investigation of the Effects of Melatonin on Electrocardiografic Findings in Rats Undergoing Acute Intense Exercise","authors":"M. Uzun, Pinar Cakan","doi":"10.4274/nkmj.galenos.2021.32032","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.32032","url":null,"abstract":"Aim: Acute intense exercise causes an additional strain on cardiovascular system. Melatonin has been known as a hormone with cardiovascular protective effects. The aim of this study is to investigate the protective effects of melatonin on cardiovascular changes in rats undergoing acute intense exercise, considering electrocardiogram (ECG) results. Materials and Methods: The 3-5-month-old 28 Wistar albino rats were used in this study and they were divided into 4 groups. The vehicle injection was applied in the control group without any exercise procedure. The groups of exercise, exercise+melatonin (intraperitoneal injection of melatonin at the dose of 10 mg/kg before exercise) and exercise+melatonin+luzindole (intraperitoneal injection of luzindole at the dose of 0.4 mg/kg and melatonin at the dose of 10 mg/kg before exercise) were run on treadmill until they were tired. ECG recording was performed at the end of the exercise. Results: A significant increase in heart rate was observed in both exercise groups. The decreasing effect of melatonin on QT and QTc prolongation in the exercise group was reported; however, this effect did not occur in the luzindol administrated group. Melatonin also decreased corticositerone levels, which increased with exercise, independent of receptor. White blood cell and neutrophile counts of the melatonin administrated group were observed to be close to that of the control group. Conclusion: These results indicate that melatonin can be used as an agent that may decrease unfavorable effects of exercise and improve the quality of exercise.","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124540566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypogammaglobulinemia Prevelance in Children with Atopic Dermatitis and the Relationship Between Immunoglobulin Levels and Eczema Severity","authors":"B. Beken, V. Çelik, Pınar Gökmirza Özdemir, M. Yazıcıoğlu","doi":"10.4274/nkmj.galenos.2021.73792","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.73792","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127939394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impacts of Intraoperative Ultrasonography Use on Revision Rate in Cases of Brain Tumor","authors":"T. Çalişkan, Tamer Tunçkale","doi":"10.4274/nkmj.galenos.2021.41636","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.41636","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"523 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124488263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of COVID-19 Pandemic on Diagnosis-treatment Process in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy","authors":"E. Çavdar, Yakup Iriagac, Kubilay Karaboyun, O. Avcı, E. Şeber","doi":"10.4274/nkmj.galenos.2021.69775","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.69775","url":null,"abstract":"","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126453168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy and Lactation-Associated Osteoporosis","authors":"M. Albayrak","doi":"10.4274/nkmj.galenos.2021.35220","DOIUrl":"https://doi.org/10.4274/nkmj.galenos.2021.35220","url":null,"abstract":"Pregnancy and lactation associated osteoporosis (PLAO) is a very rare condition seen during the last three months of the pregnancy or at early postpartum period1,2. It was first defined by Nordin and Roper3 in 1955. It is characterized by pain due to vertebral fractures. There are cases in which rarely pelvis, sacral and wrist fractures have been reported4. Its etiology has not been clearly defined. Risk factors associated with pregnancyrelated osteoporosis include genetic factors, physical inactivity, malnutrition, low body weight, osteoporotic fracture history in family members, and secondary osteoporosis3,4. The high prevalence of fracture seen in female relatives of patients diagnosed with PLAO suggests an underlying genetic component2,5,6. Anorexia and oligomenoria history can be seen in PLAO patients7.","PeriodicalId":340892,"journal":{"name":"Namık Kemal Tıp Dergisi","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121983404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}