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Avenues for the Primary Prevention of Breast Cancer in the Second Millennium 第二个千年癌症初级预防的途径
Q4 Health Professions Pub Date : 2021-12-22 DOI: 10.36570/jduhs.2021.3.1569
S. Adib
Breast cancer (BC) has recently surpassed lung canceras the most frequently diagnosed cancer worldwide,with an estimated 19.3 million new cases and almost 10 1 million deaths occurring in 2020. A steady ascension in BC incidence has been a remarkable feature in cancer epidemiology for almost a century, and has been reported in richer as well as poorer communities all over the world. This trend is no doubt associated with the ageing of the global population: “Each one-year increase of population ageing (is) associated with a nearly ½ year increase of age at BC diagnosis.
乳腺癌最近已超过肺癌,成为世界上最常诊断的癌症,据估计,2020年将有1930万新病例和近1010万例死亡。近一个世纪以来,BC发病率的稳步上升一直是癌症流行病学的一个显著特征,在世界各地的富裕和贫穷社区都有报道。这一趋势无疑与全球人口老龄化有关:“人口老龄化每增加一年,诊断为BC的年龄就会增加近半岁。
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引用次数: 0
Bacteriological Profile and Antibiogram of Neonatal Sepsis 新生儿败血症的细菌学特征和抗生素谱
Q4 Health Professions Pub Date : 2021-12-22 DOI: 10.36570/jduhs.2021.3.1240
Hira Liyakat, Mashal Khan, Neelum Tahirkheli, Bader u Nisa, M. Ashfaq
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引用次数: 1
Impact of Artificial Intelligence Integration on Surgical Outcome 人工智能集成对手术结果的影响
Q4 Health Professions Pub Date : 2021-08-16 DOI: 10.36570/jduhs.2021.2.983
M. Younis
Background: Artificial Intelligence (AI) is improving surgical practice with the technical advancement in imagery, navigation and robotic systems. Objectives: This review is aimed at assessing the role of artificial intelligence in surgical decision making during preoperative, intraoperative and postoperative periods to emphasize need of evidence-based protocols in this regard. Methods: The search strategy involving key terms pertaining to the concepts was utilized. In order to reach maximum sensitivity, a combination of the terms such as “Artificial intelligence”, “robotic surgery”, “surgical decision making”, “machine learning”, “deep learning” and “AI”  were considered. Only articles that specifically discussed the role of artificial intelligence in surgical decision making were included. Results: Fifty five studies were retrieved with exclusion of forty six of them according to inclusion criteria. Thus, nine studies were included in the final review which were arranged in table to aid data review and analysis. Conclusion:  The advancement of AI has turned modern medicine into a more effective and efficient practice to manage both acute and chronic illnesses. Important advances were made in pre-operative preparation, intra-operative support and post-operative care by using these approaches.
背景:随着图像、导航和机器人系统的技术进步,人工智能正在改善手术实践。目的:本综述旨在评估人工智能在术前、术中和术后手术决策中的作用,以强调这方面循证协议的必要性。方法:采用涉及与概念相关的关键术语的搜索策略。为了达到最大的灵敏度,考虑了“人工智能”、“机器人手术”、“手术决策”、“机器学习”、“深度学习”和“AI”等术语的组合。只包括专门讨论人工智能在外科决策中的作用的文章。结果:检索了55项研究,根据纳入标准排除了其中46项。因此,最终审查中包括了九项研究,这些研究排列在表格中,以帮助数据审查和分析。结论:  人工智能的进步使现代医学成为一种更有效、更高效的治疗急性和慢性疾病的方法。这些方法在术前准备、术中支持和术后护理方面取得了重要进展。
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引用次数: 1
Burnout among Medical Professions during Outbreaks 疫情期间医疗行业的倦怠
Q4 Health Professions Pub Date : 2021-08-15 DOI: 10.36570/jduhs.2021.2.1212
Salar M. Khan
The COVID-19 outbreak spread globally on March 11, 2020 and WHO declared this disease as a pandemic. This outbreak was sudden and spread all over the world. At the time of writing this article still COVID -19 cases are increasing among several countries. This disease has serious public health implications not only increasing morbidity and mortality but has severe psychological trauma everyone is facing since the beginning of this outbreak. The COVID -19 vaccination started at the end of December 2019 in a few countries and now it is used in several countries and the majority of people got their one or both shots hoping to get control on this outbreak soon and life will resume as usual. In my view this outbreak created the atmosphere of uncertainty, fear, anxiety, and hopelessness throughout the whole world because millions of people around the globe were dead or still dying in various hospitals around the world. After vaccination people are getting confidence to move freely in the crowded places but still need more time to come out from COVID-19 psychological trauma....
2019冠状病毒病疫情于2020年3月11日在全球蔓延,世卫组织宣布该疾病为大流行。这次疫情突然爆发,并蔓延到世界各地。在撰写本文时,一些国家的COVID -19病例仍在增加。这种疾病具有严重的公共卫生影响,不仅增加了发病率和死亡率,而且造成了自疫情开始以来每个人都面临的严重心理创伤。2019年12月底,少数国家开始接种COVID -19疫苗,现在在几个国家使用,大多数人接种了一针或两针疫苗,希望尽快控制疫情,生活将恢复正常。在我看来,这次疫情在全世界造成了不确定、恐惧、焦虑和绝望的气氛,因为全球有数百万人在世界各地的医院里死亡或仍在死亡。接种疫苗后,人们有信心在拥挤的地方自由行动,但仍需要更多时间才能从COVID-19心理创伤中走出来....
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引用次数: 0
Prevalence of Thyroid Dysfunctions in Patients with Rheumatoid Arthritis at Tertiary Care Hospital 三级医院类风湿关节炎患者甲状腺功能障碍的患病率
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1191
Nand Lal Seeran, Nasrullah Aamer, Muhammad Tariq Karim, S. Arain, Furqan Khan, A. Dahani
BACKGROUND: Thyroid dysfunctions frequently co-exist in patients with Autoimmune disorders like rheumatoid arthritis, systemic lupus erythematosus (SLE), and Vasculitis. Presence of thyroid dysfunctions in patients with rheumatoid arthritis increase the co-morbidities and mortality some time because of cardiovascular complications. Objective This study was conducted to determine the burden of thyroid dysfunctions in rheumatoid arthritis patients attending tertiary care hospital of Karachi, Pakistan. METHODS: A cross-sectional study was conducted at rheumatology clinic of a Jinnah Post Graduate Medical Centre in Karachi, Pakistan from April 2019 to January 2021. All diagnosed cases of rheumatoid arthritis having seronegative or seropositive rheumatoid arthritis were consecutively enrolled. Clinical records and laboratory data of these patients were collected along with outcome variables. RESULTS: Of 136 patients, thyroid abnormality was observed in 56 (41.2%) patients. In particular, 80 (58.8%) had normal, 8 (5.9%) had hypothyroidism, 14 (10.3%) had hyperthyroidism, 32 (10.5%) had subclinical hypothyroidism, and 2 (1.5%) had subclinical hyperthyroidism. A significantly lower hemoglobin levels (p-value <0.001), mean corpuscular volume (p-value 0.011), total leucocyte count (p-value 0.004), and platelet counts (p-value 0.040) were observed in patients with thyroid abnormality than those without thyroid abnormality. Furthermore, a significantly lower urea (p-value <0.001) and creatinine levels (p-value <0.001) were also observed among patients with thyroid abnormality than those without thyroid abnormality. CONCLUSION: In patients with rheumatoid arthritis, thyroid dysfunction has been shown to be highly prevalent. Subclinical hypothyroidism, the most common thyroid disorder and obvious hyperthyroidism were observed.
背景:甲状腺功能障碍经常在类风湿性关节炎、系统性红斑狼疮(SLE)和血管炎等自身免疫性疾病患者中共存。类风湿性关节炎患者甲状腺功能障碍会增加心血管并发症的合并症和死亡率。目的本研究旨在确定巴基斯坦卡拉奇三级医院类风湿性关节炎患者甲状腺功能障碍的负担。方法:2019年4月至2021年1月,在巴基斯坦卡拉奇真纳研究生医学中心的风湿病诊所进行了一项横断面研究。所有诊断为血清阴性或血清阳性的类风湿性关节炎病例均连续入选。收集这些患者的临床记录和实验室数据以及结果变量。结果:136例患者中,甲状腺异常56例(41.2%)。特别是,80例(58.8%)正常,8例(5.9%)甲状腺功能减退,14例(10.3%)甲状腺机能亢进,32例(10.5%)亚临床甲状腺机能减退,2例(1.5%)亚临床甲亢。甲状腺异常患者的血红蛋白水平(p值<0.001)、平均红细胞体积(p值0.011)、白细胞总数(p值0.004)和血小板计数(p值0.040)显著低于无甲状腺异常患者。此外,在甲状腺异常患者中,尿素(p值<0.001)和肌酐水平(p值p<0.001)也显著低于无甲状腺异常患者。结论:在类风湿性关节炎患者中,甲状腺功能障碍已被证明是非常普遍的。观察到亚临床甲状腺功能减退,最常见的甲状腺疾病和明显的甲状腺功能亢进。
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引用次数: 0
Assessment of Dengue Fever Knowledge and Preventive Practices among the General Population of Jeddah 吉达普通民众登革热知识和预防措施评估
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1142
H. Usman
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引用次数: 0
The Dilemma of Mobile Phone Overuse: Findings from a Quasi-Experimental Study on a Cohort of Pakistani Adolescents 手机过度使用的困境:一项针对巴基斯坦青少年队列的准实验研究结果
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1138
Maryam Sheikh, L. Baig, Zaeema Ahmer
Background Excessive mobile phone use is a health hazard among school going children. This study aimed to assess the change in knowledge and practices after providing awareness session on mobile phone usage to school-going adolescents. Methods Using a quasi-experimental design, we included 385 students, 13 to 16 years old using smartphones from three schools of Karachi, Pakistan. Convenience sampling was used to collect data through a structured questionnaire. Predictive factors of smartphone addiction were assessed, along with frequency of mobile phone use and its adverse effects on health. Analysis was done on SPSS 23. Results Before the session, 86% (n=331) students used their mobile phone to call their friends which reduced to 71.7% (n=276) (p<0.001). Average length of each call per day before was 5.68 minutes which declined to 4.92 minutes (p<0.001). Before the session, 28.1% (n=108) students thought that mobile phones have a negative health impact which increased to 84.9% (n=327) (p= 0.02). Furthermore, 50.1% (n=193) students believed that they are dependent on their mobile phone which decreased to 31.2% (n=120) (p<0.001). Conclusion We conclude that there are positive effects of awareness session on mobile phone use among adolescents. Conducting such sessions periodically among schools can lessen the usage and addiction of smartphones.
学龄儿童过度使用手机危害健康。本研究旨在评估在向学龄青少年提供手机使用意识课程后,他们在知识和实践方面的变化。方法采用准实验设计,我们纳入了来自巴基斯坦卡拉奇三所学校的385名13至16岁使用智能手机的学生。采用方便抽样,通过结构化问卷收集数据。对智能手机成瘾的预测因素、使用手机的频率及其对健康的不利影响进行了评估。使用SPSS 23进行分析。结果在培训前,86% (n=331)的学生使用手机给朋友打电话,而在培训前,这一比例降至71.7% (n=276) (p<0.001)。平均每天通话时长从5.68分钟下降到4.92分钟(p<0.001)。会议前,28.1% (n=108)的学生认为手机对健康有负面影响,这一比例上升到84.9% (n=327) (p= 0.02)。此外,50.1% (n=193)的学生认为自己依赖手机,这一比例下降到31.2% (n=120) (p<0.001)。结论认识课程对青少年手机使用有积极影响。在学校中定期举办这样的会议可以减少智能手机的使用和成瘾。
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引用次数: 0
Clinical Patterns and Risk Factors Associated With Pigmented Purpuric Dermatoses 色素性紫癜性皮肤病的临床模式及相关危险因素
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1091
Y. Mallick, Ahsun Jiwani
Objectives: Authors aimed to investigate clinical patterns, characteristics and risk factors associated with pigmented purpuric dermatoses (PPD) in Pakistani population and to correlate the relationship of various suggested aetiologic agents with PPD in our population. Methods: Retrospective analysis of 65 patients was done who visited The Indus Hospital, Karachi between October 2017 to March 2020. Demographics, comorbids, body mass index (BMI), PPD type, clinical findings, laboratory parameters and ultrasonographic findings (USF) of both lower limbs for venous insufficiency were reviewed.  Results: Mean age of patients was 42.6±13.9 years with male to female ratio of 1.2:1. Majority were housewives (40.3%). Schamberg’s disease was present in 64.6%. Obesity was present in 78.1%. Reflux in superficial venous system in 52.3% on ultrasonography, detectable dilated veins in 58.5% and presence of venous stasis in 30.8% PPD cases were found. Males were twice more commonly affected with varicosities. Hypertension (46.2%), diabetes (27.8%) and hyperlipidemia (18.5%) were most common comorbids. Statistically significant differences were detected between USF (p=0.01) and clinical varicosities (p=0.04) when Schamberg’s disease and other PPD were compared; while no association was found with respect to age, gender, occupation, BMI and type of comorbids in these two groups. Conclusion: Venous insufficiency, obesity, and comorbidities like hypertension, diabetes and hyperlipidemia were main cofactors linked with PPD in our population.
目的:作者旨在调查巴基斯坦人群中与色素性紫癜性皮肤病(PPD)相关的临床模式、特征和危险因素,并将各种建议的病因与我国人群中PPD的关系联系起来。方法:回顾性分析2017年10月至2020年3月在卡拉奇Indus医院就诊的65例患者。回顾两下肢静脉功能不全患者的人口学特征、合并症、体重指数(BMI)、PPD类型、临床表现、实验室参数及超声检查结果(USF)。结果:患者平均年龄为42.6±13.9岁,男女比例为1.2:1。大部分是家庭主妇(40.3%)。Schamberg病的发生率为64.6%。78.1%的人肥胖。超声检查发现52.3%的患者有浅静脉回流,58.5%的患者有静脉扩张,30.8%的患者有静脉淤积。男性患静脉曲张的几率是男性的两倍。高血压(46.2%)、糖尿病(27.8%)和高脂血症(18.5%)是最常见的合并症。当比较Schamberg病和其他PPD时,USF (p=0.01)和临床曲张(p=0.04)的差异有统计学意义;而两组患者的年龄、性别、职业、BMI和合并症类型均无相关性。结论:静脉功能不全、肥胖以及高血压、糖尿病和高脂血症等合并症是我国人群中PPD的主要辅助因素。
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引用次数: 0
COVID-19: A Burden on the Indian Healthcare System COVID-19:印度医疗保健系统的负担
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1173
N. Akhtar, S. Rath
The COVID-19 cases and the death toll are increasing with time so is the demand for healthcare. This critical situation demands a sufficient number of resources in all forms. This need in different parts of the world has led to an increase in demand for healthcare and medical equipment in different parts of the world which lead shortage of resources in some major parts of the world and scarcity. This paper talks about the current situation being faced by the healthcare system in India. The motive of this paper is to show a descriptive analysis of the current situation which would act as a situational guide for the policymakers. This paper has reviewed recent literature on the current Healthcare crises happening in India and tried to show the existing need for the healthcare system in the current scenario. The increasing COVID-19 cases are demanding more essential medical resource which is leading to scarcity. This paper is a detailed analysis of the current situation it also talks about various key components of the healthcare system, the current situation and focuses on managing or gaining control over the current scenario of COVID-19.
COVID-19病例和死亡人数随着时间的推移而增加,对医疗保健的需求也在增加。这一危急局势要求以各种形式提供足够数量的资源。世界不同地区的这种需求导致世界不同地区对保健和医疗设备的需求增加,从而导致世界一些主要地区资源短缺和稀缺。本文讨论了印度医疗保健系统所面临的现状。本文的动机是对当前形势进行描述性分析,为政策制定者提供情境指导。本文回顾了最近在印度发生的当前医疗危机的文献,并试图显示当前情况下医疗保健系统的现有需求。越来越多的COVID-19病例需要更多的基本医疗资源,这导致了短缺。本文是对现状的详细分析,它还讨论了医疗保健系统的各个关键组成部分,现状,并侧重于管理或控制当前的COVID-19情况。
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引用次数: 0
Complete Immunization and Reason for Non-Compliance among Childern Under Five Years of Age 五岁以下儿童完全免疫及不依从性原因分析
Q4 Health Professions Pub Date : 2021-08-12 DOI: 10.36570/jduhs.2021.2.1180
Shabeeta Bai, Rajesh Kumar, E. Rehman, Shahina Hanif, M. Ashfaq, Bader u Nisa
Objective To determine the complete coverage of childhood immunization in children under five years of age and to determine the reason of non-immunization in these children. Methods This prospective cross-sectional study was conducted at Creek General Hospital, Karachi, Pakistan from  1st January 2019 to 30th July 2019. All children 1-5 years of age irrespective of age of either gender attending the out-patient department were consecutively enrolled. Immunization status was noted by taking history from parents/guardians and immunization card as well, if available. Reason of non-vaccination was also noted. Results Of 287 children, vaccination at birth was reported by 276 (96.2%), at 6 weeks by 264 (92%), at 10 weeks by 256 (89.2%), at 14 weeks by 241 (84%), at 9 months by 230 (80.1%), and at 15 months by 220 (76.7%). Significant association was observed in between concern about vaccine safety and religion (p-value 0.013), vaccine safety and household head (p-value 0.017), long distance and birthplace (p-value 0.001), lack of money and access to media (p-value 0.044), absence of personnel and household head (p-value 0.007), child sickness and child age (p-value 0.048), child sickness and mother’s age (p-value <0.001), forgetting the day of vaccination and mother’s age (p-value 0.001), forgetting the day of vaccination and mother’s education (p-value 0.021), and complications from previous injection and mother’s age (p-value 0.040). Conclusion The findings of the current study have revealed that complete vaccination in children under five years is still very low even in urban city of Pakistan.
目的确定5岁以下儿童儿童免疫接种的完全覆盖率,并确定这些儿童未接种疫苗的原因。方法本前瞻性横断面研究于2019年1月1日至2019年7月30日在巴基斯坦卡拉奇克里克综合医院进行。所有1-5岁的儿童,无论性别年龄,都连续进入门诊。通过获取父母/监护人的病史和免疫卡(如果有的话)来记录免疫状况。还指出了未接种疫苗的原因。结果287名儿童中,276名(96.2%)、6周接种264名(92%)、10周接种256名(89.2%)、14周接种241名(84%)、9个月接种230名(80.1%)和15个月接种220名(76.7%),远距离和出生地(p值0.001),缺乏资金和媒体(p值0.044),没有工作人员和户主(p值0.007),儿童疾病和儿童年龄(p值0.04 8),儿童患病和母亲年龄(p值<0.001),忘记接种疫苗的日期和母亲的年龄(p价值0.001),忘记疫苗接种和母亲教育的日期(p值0.021),以及以前注射的并发症和母亲的年龄(p值0.040)。结论目前的研究结果表明,即使在巴基斯坦城市,五岁以下儿童的完全疫苗接种率仍然很低。
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引用次数: 0
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Journal of the Dow University of Health Sciences
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