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Posterolateral migration of complete vertebral body in neglected tuberculosis of the spine 被忽视的脊柱结核中完整椎体的后外侧移位
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_79_21
Svareen Kaur, Roop Singh, Hemant More, M. Khanna
The most common presentation of tuberculosis (TB) of the spine is paradiscal lesion secondarily involving adjacent disc and vertebral bodies. If not diagnosed early, it can lead to extensive destruction and atypical features. We report a patient who presented late with posterolateral migration of the vertebral body and multifocal spinal involvement. A 30-year-old female presented with back pain, progressive spinal deformity, and paraparesis. Plain X-rays, computed tomography scans, and magnetic resonance imaging revealed multifocal extensive TB of the spine with posterolateral migration of the first lumbar vertebra. The vertebral body showed erosions. Posterior elements involvements with pars interarticularis defects of 12th dorsal to 2nd lumbar vertebra were observed. The patient was planned for stabilization of the spine along with excision of the migrated vertebra along with antituberculous treatment, but she refused surgery. The authors discuss the pathogenesis of such a rare event and stress the early detection of this complication.
脊柱结核(TB)最常见的表现是继发累及邻近椎间盘和椎体的天堂状病变。如果不及早诊断,它可能导致广泛的破坏和非典型特征。我们报告了一位晚期出现椎体后外侧移位和多灶性脊柱受累的患者。一名30岁女性,表现为背部疼痛,进行性脊柱畸形和截瘫。x光平片、计算机断层扫描和磁共振成像显示脊柱多灶性广泛结核伴第一腰椎后外侧移位。椎体呈糜烂。观察第12至第2腰椎背侧关节间部缺损累及后路因素。患者计划在稳定脊柱的同时切除移位椎体并进行抗结核治疗,但她拒绝手术。作者讨论了这种罕见事件的发病机制,并强调早期发现这种并发症。
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引用次数: 0
The dimensions of pronator quadratus and its neurovascular structures – A cadaveric study with its clinical implications in distal forearm surgeries 旋前方肌的尺寸及其神经血管结构-前臂远端手术的尸体研究及其临床意义
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_67_21
S. Ramalingam, Deepa Somanath
Introduction: The pronator quadratus is one of the deep muscles of the front of the forearm. The neurovascular supply of the muscle is derived from the anterior interosseous nerve and vessels. This muscle is approached in various surgical procedures involving the distal radius. Its nerve can be utilised as a graft in case of peripheral nerve lesions and the anterior interosseous artery perforator flap is used for wrist and hand surgeries. Hence, the anatomy of the muscle and its neurovascular pedicle is needed in orthopedic surgeries. Materials and Methods: In this study, 84 upper limbs from 24 male and 18 female cadavers, age ranging from 55 to 78 years, were dissected to study the pronator quadratus muscle and its neurovascular supply in the Department of Anatomy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry. Various levels of measurements regarding the length and width of the muscle were considered. The number of branches of its neurovascular structures and their levels of entry into the muscle from various landmarks was measured. The Student t-test was applied to identify the P-value regarding the difference between the subjects. Results: No significant differences were observed regarding the measurements of the muscle and its neurovascular structures between male and female cadavers. Conclusion: This study can be useful for the surgeries involving the lower part of front of forearm. Since no significant difference was found between the genders regarding the variables, the morphometry of the muscle and its supply can be generalised for both sexes.
简介:旋前方肌是前臂前部的深层肌肉之一。肌肉的神经血管供应来源于前骨间神经和血管。在涉及桡骨远端的各种外科手术中都要接近这块肌肉。其神经可用于周围神经病变的移植,前骨间动脉穿支皮瓣可用于腕部和手部手术。因此,在骨科手术中需要对肌肉及其神经血管蒂进行解剖。材料与方法:本研究在本地治里的Sri Manakula Vinayagar医学院解剖学系解剖了24具男性和18具女性尸体的84具上肢,年龄在55 ~ 78岁之间,研究了旋前方肌及其神经血管供应。考虑了关于肌肉长度和宽度的各种测量水平。测量了其神经血管结构分支的数量及其从不同地标进入肌肉的水平。采用学生t检验来确定受试者之间差异的p值。结果:男性和女性尸体的肌肉和神经血管结构测量无显著差异。结论:本研究对前臂前下半部分的手术有一定的指导意义。由于在变量方面没有发现性别之间的显著差异,因此肌肉的形态测量及其供应可以推广到两性。
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引用次数: 0
To evaluate the role of intralesional injection of platelet-rich plasma versus corticosteroid (triamcinolone) in plantar fasciitis 评价富血小板血浆与皮质类固醇(曲安奈德)在足底筋膜炎中的作用
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_9_21
Mahendra Solanki, R. Kelkar, Pawan Baghel
Introduction: Plantar fasciitis is an aseptic inflammation of the plantar fascia and also the most common cause of plantar heel pain.Approximately more than 10% of the population is affected by it over their lifetime. Aims and Objectives: The aim of this study is to evaluate the role of platelet-rich plasma (PRP) versus corticosteroid (triamcinolone) therapy in plantar fasciitis and to study the complications associated with both the procedures and their management. Materials and Methods: The study included 36 patients of plantar fasciitis (fulfilling the inclusion criteria) who presented to the OPD/Casualty of Department of Orthopaedics and Traumatology, M.G.M. Medical College and M.Y. Hospital, Indore, between September 2018 and August 2020. The study was a prospective and interventional type. Results: The mean Roles and Maudsley Subjective Pain score (RMSPS) score at pretreatment was 3.72 ± 0.46 for PRP and 3.72 ± 0.46 for steroids; at 1 month, it was 1.61 ± 0.78 for PRP and 1.44 ± 0.70 for steroids; and at 6 months, it was 1.22 ± 0.55 for PRP and 1.94 ± 0.73 for steroids. The mean Visual Analog Scale (VAS) score at pretreatment was 7.72 ± 0.96 for PRP and 7.78 ± 1.0 for steroids; at 1 month, it was 2.89 ± 1.68 for PRP and 2.50 ± 1.47 for steroids; and at 6 months, it was 1.28 ± 1.49 for PRP and 2.61 ± 1.69 for steroids. PRP injections have shown effectiveness in providing pain relief, improving function in plantar fasciitis patients. As a result, VAS and RMSPS score was significantly reduced (P = 0.015) at 6 months as compared to preprocedure and thus proved the effectiveness of the PRP therapy. It also shows that PRP is a better method in reducing pain in plantar fasciitis compared to steroid injection. Conclusion: Our study demonstrates PRP injection to be an effective and well-tolerated alternative to corticosteroid injection in the management of chronic plantar fasciitis with an added advantage of almost no side effects due to its biological nature and better patient compliance.
足底筋膜炎是足底筋膜的无菌性炎症,也是足底跟痛的最常见原因。大约有超过10%的人一生中都会受到这种疾病的影响。目的和目的:本研究的目的是评估富血小板血浆(PRP)与皮质类固醇(曲安奈德)治疗足底筋膜炎的作用,并研究两种治疗方法及其处理的相关并发症。材料与方法:本研究纳入了2018年9月至2020年8月在印多尔M.G.M.医学院和M.Y.医院骨科/伤病科就诊的36例足底筋膜炎患者(符合纳入标准)。本研究为前瞻性干预性研究。结果:预处理时PRP组的平均role和Maudsley主观疼痛评分(RMSPS)为3.72±0.46,类固醇组为3.72±0.46;1个月时,PRP为1.61±0.78,类固醇为1.44±0.70;6个月时,PRP为1.22±0.55,类固醇为1.94±0.73。预处理时视觉模拟量表(VAS)平均评分PRP为7.72±0.96,类固醇为7.78±1.0;1个月时,PRP为2.89±1.68,类固醇为2.50±1.47;6个月时,PRP为1.28±1.49,类固醇为2.61±1.69。PRP注射在提供疼痛缓解,改善足底筋膜炎患者的功能方面显示出有效性。结果,与术前相比,6个月时VAS和RMSPS评分显著降低(P = 0.015),从而证明了PRP治疗的有效性。这也表明与类固醇注射相比,PRP是一种更好的减轻足底筋膜炎疼痛的方法。结论:我们的研究表明,PRP注射是治疗慢性足底筋膜炎的一种有效且耐受性良好的替代皮质类固醇注射的方法,由于其生物学性质和更好的患者依从性,它几乎没有副作用。
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引用次数: 0
Bilateral bunionette in rheumatoid arthritis 类风湿性关节炎的双侧拇囊炎
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_48_22
A. Agrawal, A. Garg, Deepak Garg, R. Ranjan
Introduction: Tailor's bunion or Bunionette deformities were described by Davies et al. as abnormal, painful bony prominence on the lateral aspect of the fifth metatarsal head. This prominence, though present in many individuals, seldom causes symptoms. Most deformities can be managed conservatively, and surgical interventions will be needed only for refractory cases presenting with chronic pain. Various surgical interventions (percutaneous, mini-open, open), including osteotomies at different level, has been described in the literature. Case: A thirty-three-year-old female house-maker presented with swelling over the bilateral fifth metatarsal lateral aspect and pain while walking for the last six months. The patient is a known case of Rheumatoid arthritis controlled on medication. The patient underwent Lateral exostectomy resection for bilateral swelling, At one year follow up, the patient had good functional outcome with no recurrence. Conclusion: Tailor's bunion deformity, although morphologically common, is rarely symptomatic. Its management involves identifying the cause, thorough clinical and radiographic evaluation of the deformity, and deciding the best surgical procedure to obtain optimal results.
Davies等人将Tailor’s拇囊炎或拇囊炎畸形描述为第五跖骨头外侧异常、疼痛的骨突出。这种突出,虽然存在于许多个体,很少引起症状。大多数畸形可以保守治疗,只有出现慢性疼痛的难治性病例才需要手术干预。各种手术干预(经皮、小切口、开放),包括不同水平的截骨术,已在文献中进行了描述。病例:一名三十三岁女性房屋工人,表现为双侧第五跖骨外侧肿胀,行走时疼痛六个月。该患者为已知的类风湿关节炎病例,经药物控制。患者因双侧肿胀行外侧外骨切除术,随访1年,功能预后良好,无复发。结论:泰勒拇囊炎畸形虽然在形态学上很常见,但很少有症状。其治疗包括确定病因,对畸形进行彻底的临床和影像学评估,并决定最佳的手术方法以获得最佳结果。
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引用次数: 0
Functional outcome of delayed surgical fixation of capitellar fractures treated by open reduction and internal fixation with herbert screw 赫伯特螺钉切开复位内固定治疗小头骨折延迟手术固定的功能效果
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_46_22
S. Keshkar, Riddhideb Barman, Mohammad Akhtar
Introduction: Capitellar fractures are rare injuries and difficult to manage, especially so if the patient presents late. Treatment is almost always operative. The purpose of this study is to evaluate the functional outcome of capitellar fractures in adults treated by open reduction and internal fixation (ORIF) with cannulated compression headless screws (Herbert screw) with an inadvertent delay of 2 weeks or more. Materials and Methods: Twelve patients (4 males and 8 females) of capitellum fracture who were reported after an inadvertent delay of at least 2 weeks, with near-normal elbow range of motion, operated by ORIF with Herbert screw, were studied retrospectively from April 2013 to March 2019. All cases were operated between 2 to 3 weeks of injury. All patients had a follow-up for a mean period of 34 months, and the final functional outcome was assessed using Mayo Elbow Performance Index (MEPI) and by radiology. Results: The mean MEPI score was 92.9 points, and as per this evaluation of the functional rating, all but one patient had excellent results. The mean range of elbow flexion/extension was 125 (90–140), while the range of movement in supination/pronation was 170 (130–180). Conclusion: ORIF of capitellum fractures with Herbert screw was found to be superior and gives excellent result, even with a delay of around 2 weeks. Preoperative computed tomography is helpful not only to know clear picture of fracture configuration but also to choose right surgical approach and right implant. Apart from stable internal fixation, early mobilization and rehabilitation are the keys for optimum functional outcome.
小头骨折是一种罕见且难以治疗的损伤,尤其当患者出现较晚时。治疗几乎总是手术。本研究的目的是评估成人小头骨折采用空心加压螺钉(Herbert螺钉)切开复位内固定(ORIF)治疗的功能结果,并将治疗延迟2周或更长时间。材料与方法:回顾性研究2013年4月至2019年3月12例(男4例,女8例)小头骨折患者,均为肘关节活动范围接近正常,经ORIF + Herbert螺钉手术治疗,术后延迟至少2周。所有病例均于伤后2 ~ 3周手术。所有患者的随访时间平均为34个月,使用Mayo肘部表现指数(MEPI)和放射学评估最终功能结局。结果:MEPI平均评分为92.9分,根据功能评分的评价,除1例外,其余均为优等。肘关节屈伸平均范围为125(90-140),旋前/旋前活动范围为170(130-180)。结论:Herbert螺钉ORIF治疗肱骨小头骨折是一种较好的治疗方法,即使延迟2周左右也能获得很好的疗效。术前计算机断层扫描不仅有助于了解骨折形态的清晰图像,而且有助于选择正确的手术入路和正确的植入物。除了稳定的内固定外,早期活动和康复是获得最佳功能结果的关键。
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引用次数: 0
Evaluation of functional and radiological outcome of five-pin technique in management of distal end radius fractures 五针技术治疗桡骨远端骨折的功能及影像学评价
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_113_21
Mahendra Solanki, D. Sharma, R. Prasad, Mitul K. Jain
Introduction: Distal end radius fractures are the most common fractures of the upper extremity. The most common mode of injury is a fall on outstretched hand. Closed reduction and percutaneous pinning with “the five-pin technique” improve the reliability of fixation. The current study aimed to assess the clinical and functional outcome of fixation of distal radius fractures using the five-pin technique. Materials and Methods: Thirty patients with fracture of distal end radius Frykman type 1 and 2 were subjected to close reduction and K-wire fixation by five-pin technique. Results: Functional outcome-using Obrien scoring system for functional outcome, there was 90%–100% score in 11 patients, 80%–89% in 18 patients, and <80 in one patient. Radiological outcome-using Sarmiento modification Lindstrom criteria for radiological outcome, 11 patients had excellent results, and 18 had good results, and one had fair results. Conclusion: “The five-pin technique” is a versatile tool which provides optimum functional and radiological outcomes.
桡骨远端骨折是上肢最常见的骨折。最常见的受伤方式是伸开的手摔倒。闭合复位经皮钉钉“五针技术”提高了固定的可靠性。目前的研究旨在评估使用五针技术固定桡骨远端骨折的临床和功能结果。材料与方法:采用五针技术对30例桡骨远端Frykman 1型和2型骨折患者进行闭合复位和k线固定。结果:功能结局-使用Obrien评分系统进行功能结局评分,11例患者评分为90%-100%,18例患者评分为80%-89%,1例患者评分<80。放射预后-使用Sarmiento修改Lindstrom放射预后标准,11例患者预后良好,18例预后良好,1例预后尚可。结论:“五针技术”是一种多功能工具,可提供最佳的功能和放射效果。
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引用次数: 1
Management of extra articular distal femoral fractures with nail plate combination 钉钢板联合治疗股骨远端关节外骨折
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_103_21
A. Sharma, D. Varma, Umesh Vyas, A. Bohra, ShivBhagwan Sharma
Background: Junctional distal femur fractures are considered difficult to unite and often can led to a degree of disability. The incidence of malunion, nonunion, and infection is relatively high in many reported series. In elderly patients, low-energy distal femur fractures can cause devastating injuries, carrying high rates of morbidity and mortality. Operative fixation can be more challenging in comminuted fractures of osteoporotic bones. The management of junctional fractures of the distal femur by using the nail plate combination (NPC) technique can provide stable, well-balanced fixation, allowing for immediate weight-bearing and early mobilization and improve quality of life. Materials and Methods: A prospective randomized study including 16 patients with distal femur extraarticular and junctional fractures, was conducted in the department of orthopedic surgery Jhalawar medical college and SRG hospital Jhalawar, from May 2019 to June 2021. There were 9 male and 7 female patients, age range from 43 years to 70 years, with a mean age being 53 years. The average length of follow-up was 18.5 months (12 months to 24 months). Results: Patients followed up at 1 month, 3 months, 6 months, annually thereafter. Regular fracture healing was observed in 15 cases. Delayed union seen in 1 case who had infection postoperatively, which was treated with debridement and antibiotics as culture and sensitivity. mild rotational misalignment (~5°) seen in one case and there was no axial misalignment (Varus/valgus angulations) was found in any case. There were no implant failures. Conclusion: In our study, functional results trended toward better outcomes in nails plates combinations in terms of knee flexion, early weight-bearing, less union time, and better alignment. NPC system could take the challenges such as poor bone stock, severe comminution both metaphyseal and diaphyseal region.
背景:股骨远端交界性骨折被认为难以愈合,通常会导致一定程度的残疾。在许多报道的系列中,不愈合、不愈合和感染的发生率相对较高。在老年患者中,低能量股骨远端骨折可造成破坏性损伤,具有很高的发病率和死亡率。在骨质疏松性粉碎性骨折中,手术固定更具挑战性。采用钉板联合(NPC)技术治疗股骨远端关节骨折可提供稳定、平衡的固定,允许立即负重和早期活动,提高生活质量。材料与方法:2019年5月至2021年6月,在贾哈拉瓦医学院骨科和贾哈拉瓦SRG医院对16例股骨远端关节外骨折患者进行前瞻性随机研究。男9例,女7例,年龄43 ~ 70岁,平均53岁。平均随访时间18.5个月(12 ~ 24个月)。结果:随访时间分别为1个月、3个月、6个月,此后每年随访一次。15例骨折正常愈合。术后感染延迟愈合1例,行清创和抗生素培养及敏感性治疗。1例出现轻度旋转错位(~5°),其余病例均未发现轴向错位(内翻/外翻角度)。没有植入失败。结论:在我们的研究中,在膝关节屈曲、早期负重、更短的愈合时间和更好的对齐方面,钉钢板组合的功能结果趋向于更好的结果。鼻咽癌系统可以应对骨缺损、干骺端和干骺端严重粉碎等挑战。
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引用次数: 0
A novel technique for posterior cruciate ligament tibial avulsion fixation through the burks and schaffer approach 采用burks - schaffer入路固定胫骨后交叉韧带撕脱伤的新技术
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_6_21
Akshat Vijay, D. Bairwa, R. Goel, Amit Gupta
Introduction: Numerous techniques for the treatment of posterior cruciate ligament (PCL) avulsion fractures have been described in literature from closed reduction to definitive fixation, both open and arthroscopically assisted fixation. Aim: In this study, we evaluated the clinical and functional outcome after open reduction and internal fixation of tibial avulsion injuries of the PCL using number 5 polyester sutures (Ethicon-Ethibond excel) with Titanium AL (Tit) endobutton (Nebula Surgicals Private Limited, India) through burks and Schaffer posteromedial approach. Materials and Methods: It was a prospective study of 22 patients of PCL tibial avulsion fractures; fixed using number 5 polyester sutures with Tit endobutton through burks and Schaffer approach with the patient in the prone position. We included only those patients who had isolated PCL avulsion injuries and came within 12 weeks of injury. The final functional outcome was compared using the Lysholm knee scoring system. Student's t-tests were used for intergroup comparison of Lysholm knee scores before and after surgery. Results: The mean follow-up was of 11.9 months, with the loss of two patients in follow-up. Bony union was achieved in all patients within 8–15 weeks (mean-11.6 weeks). The average flexion of 122.8° with full extension achieved in all patients. Slight instability (1+) was noted in four patients. The Lysholm functional score was excellent in 16 patients and good in four patients with an average score of 94.6 ± 4.6. Conclusion: Using sutures and endobuttons for PCL tibial avulsion fixation provides secure fixation leading to satisfactory functional and clinical outcomes as well as omits placement of any hardware in joint, thus obviating risk of joint damage and burden of second surgery for removing the implant.
文献中描述了许多治疗后交叉韧带(PCL)撕脱性骨折的技术,从闭合复位到最终固定,包括开放和关节镜辅助固定。目的:在本研究中,我们采用5号聚酯缝线(Ethicon-Ethibond excel)和钛AL (Tit)内扣(Nebula Surgicals Private Limited, India)经burks和Schaffer后内侧入路,对PCL胫骨撕脱伤切开复位内固定后的临床和功能结果进行了评估。材料与方法:对22例PCL胫骨撕脱骨折患者进行前瞻性研究;采用5号聚酯缝线与乳头内扣通过burks和Schaffer入路固定,患者俯卧位。我们只包括那些孤立的PCL撕脱伤患者,并在12周内受伤。使用Lysholm膝关节评分系统对最终功能结果进行比较。采用学生t检验对手术前后Lysholm膝关节评分进行组间比较。结果:平均随访11.9个月,失访2例。所有患者均在8-15周(平均11.6周)内实现骨愈合。所有患者的平均屈曲为122.8°,完全伸直。4例患者出现轻度不稳定(1+)。Lysholm功能评分优16例,良4例,平均94.6±4.6分。结论:采用缝线和内扣进行PCL胫骨撕脱固定,可获得满意的功能和临床效果,且无需在关节内放置任何硬体,避免了关节损伤的风险和第二次手术取出假体的负担。
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引用次数: 0
Hybrid external fixator for correction of genu valgum in an adult 混合外固定架矫正成人膝外翻一例
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_61_21
Tanmoy Mohanty, Madhuchhanda Pattnaik, G. Sethy, R. Jee
Sometimes genu valgum in an adult poses a challenge to orthopedic surgeons because the deformity is very gross if it developed due to injury or infection in early childhood. If the femoral condyle is found to be hypoplastic, then the corrective osteotomy site is very close to the joint. It may be difficult to manage with a conventional fixator and a hybrid fixator may become a necessity. A limb reconstruction system (LRS) is less cumbersome than ring fixators when fixed to the thigh. A hybrid fixator fabricated using a twin-ring Ilizarov system attached to an LRS was found to be very useful during the management of corrective osteotomy of genu valgum in an adult. A special clamp was designed to fix the Ilizarov portion to the end of the rail system of LRS. Here, the use of such a hybrid fixator to correct the deformity of the right knee in a 27-year-old person has been described in detail.
有时,成人膝外翻对矫形外科医生来说是一个挑战,因为如果它是由于儿童早期受伤或感染而形成的,则畸形非常严重。如果发现股骨髁发育不全,则矫正截骨部位非常靠近关节。使用常规固定器可能难以管理,混合型固定器可能成为必要。肢体重建系统(LRS)在固定在大腿上时比环形固定器更麻烦。在成人膝外翻矫正截骨术中,将双环Ilizarov系统与LRS连接制成混合固定架非常有用。设计了一个特殊的夹具来固定Ilizarov部分到LRS的轨道系统的末端。本文详细描述了一位27岁患者使用这种混合固定架矫正右膝畸形的情况。
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引用次数: 0
Evaluation of serum procalcitonin levels in patients of acute osteomyelitis and septic arthritis 急性骨髓炎和脓毒性关节炎患者血清降钙素原水平的评价
Pub Date : 2022-01-01 DOI: 10.4103/jotr.jotr_16_21
Narendra Kumar, V. Pandey, D. Sharma, M. Patralekh, H. Lal
Aims: The aim is to study the role of serum procalcitonin (PCT) levels in early diagnosis of acute osteomyelitis (OM) and septic arthritis (SA). Settings and Design: This is a prospective study in a tertiary hospital. Subjects and Methods: This study was done at a tertiary care hospital. Thirty-nine patients with SA or acute OM who attended the outpatient department or emergency were included in the study. 39 patients were taken as control group out of which one patient lost to follow-up, so 38 patients were left with control group. PCT level was evaluated by using immunoluminetric assay and a cutoff value of 0.5 ng/ml was taken as positive. After collection of data, sensitivity, specificity, positive predictive value, and negative predictive value are calculated for PCT. Statistical Analysis Used: Mann–Whitney U-test and Kruskal–Wallis test were used. Results: The sensitivity for PCT was 94.87 (95% confidence interval [CI] 82.68–99.37), specificity was 86.84 (95% CI 71.91–95.59), positive predictive value was 88.10%, and negative predictive value was 94.29%, when taking cutoff of 0.5 ng/ml. We have taken 0.5 ng/ml as a cutoff point for PCT; however, as per receiver operator characteristic of this study, the cutoff point was 1.1 ng/ml. Conclusions: This study clearly showed that PCT can be helpful in the early diagnosis of OM and SA, along with other indicators such as total leukocyte count, erythrocyte sedimentation rate, and C-reactive protein.
目的:研究血清降钙素原(PCT)水平在急性骨髓炎(OM)和脓毒性关节炎(SA)早期诊断中的作用。环境与设计:这是一项在三级医院进行的前瞻性研究。研究对象和方法:本研究在一家三级保健医院进行。39例在门诊或急诊就诊的SA或急性OM患者被纳入研究。选取39例患者作为对照组,其中1例患者未随访,故对照组为38例。采用免疫荧光法测定PCT水平,以0.5 ng/ml为阳性。收集资料后,计算PCT的敏感性、特异性、阳性预测值、阴性预测值。采用统计学分析:采用Mann-Whitney u检验和Kruskal-Wallis检验。结果:PCT的敏感性为94.87(95%可信区间[CI] 82.68 ~ 99.37),特异性为86.84 (95% CI 71.91 ~ 95.59),以0.5 ng/ml为截止值时,阳性预测值为88.10%,阴性预测值为94.29%。我们将0.5 ng/ml作为PCT的临界值;然而,根据本研究的受试者操作者特征,截止点为1.1 ng/ml。结论:本研究明确显示PCT与其他指标如白细胞总数、红细胞沉降率、c反应蛋白等一起有助于OM和SA的早期诊断。
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引用次数: 0
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Journal of Orthopedics Traumatology and Rehabilitation
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