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Lassa Fever Infection among Healthcare Workers during the 2018 Outbreak in Nigeria 2018年尼日利亚疫情期间卫生保健工作者中的拉沙热感染
Q4 Social Sciences Pub Date : 2023-07-04 DOI: 10.3126/ijosh.v13i3.44269
E. Ogbaini-Emovon, F. Erah, Emmanuel Friday Osagiede, C. Nnadi, Y. Ogbetere, E. Tobin, D. Asogun, Martha Okonofua, G. Akpede, P. Akhideno, C. Erameh, M. Rafiu, W. Ovienria, C. Ephraim-Ogbaini, C. Ojide, U. Unigwe, F. Ireye, S. Günther, S. Duraffour, S. Okogbenin
Introduction: Healthcare workers (HCWs) are potentially exposed to infection during viral hemorrhagic fever outbreaks. In the wake of 2018, Nigeria experienced an unprecedented surge in cases of Lassa fever (LF), which affected HCWs. To guide infection prevention and control (IPC) strategies in similar settings, we characterize HCWs' infection and describe the gaps in IPC standards and practices during the outbreak.Methods: Data was collected using a structured questionnaire, interview, and review of case notes of 21 HCW with laboratory-confirmed Lassa fever who were treated at the Irrua Specialist Teaching Hospital (ISTH) Irrua and the Alex-Ekwemen Federal Teaching Hospital, Abakaliki (AEFETHA), between 1st January and 27th May 2018. Information collected was the patients' socio-demographic characteristics, date of potential exposure and onset of illness, nature, and type of exposure, clinical features, outcome, use of personal protective equipment (PPE), and personnel IPC training and were analyzed using descriptive statistics with Microsoft Excel.Results: The study included 21 HCWs, and 12 (57.14%) were doctors. The case fatality rate was 23%. Nearly two-thirds (62%) of the HCWs could describe a likely procedure leading to their exposure and infection. Among 13 HCWs, 85% had multiple blood and body fluids exposure, while 15% had needle stick injury or scalpel cut. About one-fifth of the participants had received some IPC training.Conclusion: Limited IPC adherence and inappropriate risk assessment were identified as factors leading to Lassa fever exposure and infection among HCWs. There is an urgent need to provide IPC training for all HCWs and to ensure an adequate supply of IPC materials to all healthcare facilities as part of emergency preparedness, especially in LF endemic areas.
简介:在病毒性出血热暴发期间,卫生保健工作者(HCWs)可能暴露于感染。2018年之后,尼日利亚的拉沙热病例出现了前所未有的激增,影响了卫生保健工作者。为了指导类似环境中的感染预防和控制(IPC)战略,我们描述了卫生保健工作者的感染特征,并描述了疫情期间IPC标准和做法的差距。方法:采用结构化问卷、访谈和对2018年1月1日至5月27日期间在伊鲁阿专科教学医院(ISTH)和阿巴卡利基alexekwemen联邦教学医院(AEFETHA)接受治疗的21例实验室确诊拉沙热HCW患者的病例记录进行收集数据。收集的信息包括患者的社会人口学特征、潜在暴露日期和发病日期、暴露性质和类型、临床特征、结果、个人防护装备(PPE)的使用情况和人员IPC培训,并使用Microsoft Excel进行描述性统计分析。结果:共纳入21名卫生保健员,其中12名为医生,占57.14%。病死率为23%。近三分之二(62%)的卫生保健工作者可以描述一个可能导致他们接触和感染的程序。13名医护人员中,85%有多处血液和体液暴露,15%有针刺伤或手术刀割伤。大约五分之一的参与者接受过IPC培训。结论:有限的IPC依从性和不适当的风险评估是导致卫生保健工作者拉沙热暴露和感染的因素。迫切需要为所有卫生保健员提供预防感染的培训,并确保向所有卫生保健设施提供足够的预防感染材料,作为应急准备的一部分,特别是在LF流行地区。
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引用次数: 0
HPLC analysis of biomarkers of Toluene and Xylene in human urine samples 人尿液中甲苯和二甲苯生物标志物的HPLC分析
Q4 Social Sciences Pub Date : 2023-07-04 DOI: 10.3126/ijosh.v13i3.46615
P. Maurya, A. Yadav, P. Maurya
Introduction: Urinary Hippuric acid (HA) and Methylhippuric acid (MHA) are considered reliable biomarkers for monitoring exposure to toluene and xylenes. A simple and robust HPLC method for simultaneous determination of HA and MHA in urine samples was developed and validated as per Internation Conference on Harmonization (ICH) Q2 guidelines.Methods: Mobile phase consisting of two solvents A & B, solvent A was 0.1% TFA in water, and solvent B was 0.1% TFA in acetonitrile.  Separation was performed in gradient elution mode and the time program was as follows - Time (min)/%B: 0/20, 4/20, 11/80, 11.1/90, 16/90, 16.1/20, 25/20. The detection wavelength was 205 nm.Results: The limits of detection (LOD) and quantification (LOQ) of HA in urine were 0.3 and 1.0 mg/L, and for MHA were 0.25 mg/L and 1.0 mg/L respectively and the recovery for HA and MHA were 95% and 98.9% respectively. Conclusion: The developed method was successfully applied for the analysis of urine samples.
尿马尿酸(HA)和甲基马尿酸(MHA)被认为是监测甲苯和二甲苯暴露的可靠生物标志物。根据国际协调会议(ICH) Q2指南,建立了一种同时测定尿液样本中HA和MHA的简单高效液相色谱方法并进行了验证。方法:流动相由两种溶剂A和B组成,溶剂A为0.1% TFA水溶液,溶剂B为0.1% TFA乙腈水溶液。采用梯度洗脱模式进行分离,时间程序如下:time (min)/%B: 0/20、4/20、11/80、11.1/90、16/90、16.1/20、25/20。检测波长为205 nm。结果:尿中HA的检出限(LOD)和定量限(LOQ)分别为0.3和1.0 mg/L, MHA的检出限(LOD)和定量限(LOQ)分别为0.25和1.0 mg/L,回收率分别为95%和98.9%。结论:所建立的方法可用于尿样的分析。
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引用次数: 0
Mental Health among Automobile industry workers in Chennai – A Cross-sectional study from a Single Industrial unit 金奈汽车工业工人的心理健康状况——来自单一工业单位的横断面研究
Q4 Social Sciences Pub Date : 2023-07-04 DOI: 10.3126/ijosh.v13i3.47093
Jeevanesan Vinoth, S. Balaji, Dinesh Kumar Ganesan, T. Jain
Introduction: Working in a mentally healthy place is necessary for people. Adverse mental health conditions can lead to disruption in work which in turn causes absenteeism, low productivity, and financial constraints. This study intends to assess the levels of depression, anxiety and stress and to determine its associated factors among the workers in the automobile industry in Chennai.Methods: A cross-sectional study was conducted among 227 Automobile industry workers in Chennai, India. A semi-structured questionnaire was used to collect information about the socio-demographic and working details of the study subjects, while the Depression Anxiety Stress Scale (DASS -21) was used to assess mental health status. Descriptive variables were expressed as proportions, while Pearson's Chi-square test was used to study the association between dependent and independent variables.Results: A total number of 227 participants were included in the study. More than 80 % of the workers were permanent employees. The prevalence of Depression, anxiety and stress among the study subjects are 38.8%, 43.6 % and 26.9 %, respectively. Workers in the middle age group of 30- 39 years had a higher risk of developing depression, anxiety, and stress than those in the other age groups. For Depression, age, type of family, employment status, and working experience were statistically significant (p<0.05). The sleeping hours, comorbidities, substance use, co-worker support, and supervisor support of the workers were the factors that showed no association with Depression, anxiety, and stress.Conclusion: There is a need for attention to be paid to the development of a healthy psychosocial workplace climate which should be supported by stronger workplace support.
在一个心理健康的地方工作对人们来说是必要的。不良的精神健康状况可导致工作中断,进而导致缺勤、生产力低下和财政拮据。本研究旨在评估金奈市汽车工业工人的抑郁、焦虑和压力水平,并确定其相关因素。方法:对印度金奈市227名汽车工业工人进行横断面调查。采用半结构化问卷收集研究对象的社会人口学信息和工作细节,采用抑郁焦虑压力量表(DASS -21)评估心理健康状况。描述性变量用比例表示,因变量与自变量之间的相关性采用Pearson卡方检验。结果:共纳入227名受试者。超过80%的工人是正式雇员。研究对象中抑郁、焦虑和压力的患病率分别为38.8%、43.6%和26.9%。30- 39岁的中年人比其他年龄段的人患抑郁症、焦虑症和压力的风险更高。对于抑郁症,年龄、家庭类型、就业状况、工作经验差异有统计学意义(p<0.05)。睡眠时间、合并症、药物使用、同事支持和主管支持是与抑郁、焦虑和压力无关的因素。结论:需要重视营造健康的工作场所心理环境,并辅以更强有力的工作场所支持。
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引用次数: 0
Heat Stress Vulnerability Among Small-Scale Factory Workers and Adaptive Strategies in Ahmedabad: a Cross Sectional Study 艾哈迈达巴德小规模工厂工人的热应激脆弱性及其适应策略:一项横断面研究
Q4 Social Sciences Pub Date : 2023-07-04 DOI: 10.3126/ijosh.v13i3.44241
Hardik R. Parmar, N. Gawde
Introduction: Global warming is likely to affect certain groups such as workers in heat-producing industries. With limited research exploring such an important area, this study aimed to explore the heat stress vulnerability and adaptive strategies of indoor small-scale factory workers.Methods: This was a cross-sectional study and a mixed-method approach was used. The study setting was small-scale factory units. The quantitative component included environmental and biological monitoring from six units of steel rolling mills and foundry in the summer and winter seasons. The study was conducted during the period of November-2018 and May 2019. Heat stress was measured among workers using a portable Wet Bulb Globe Temperature (WBGT) meter. The physiological parameters of workers were also measured. The qualitative component included in-depth interviews of workers and supervisors from eleven units.Results: The maximum temperatures recorded at steel rolling mills and foundry crossed Occupational Safety and Health Administration (OSHA) threshold (27.5℃) in summer as well as winter. The mean WBGT at the steel rolling mill recorded 31.5℃. The physiological measurements of workers also crossed the threshold level for heart rate and oral temperature in steel rolling and foundry units. The units had mechanisms to dissipate heat but lack a temperature monitoring mechanism inside the units. The workers wore lighter or fewer clothes as an adaptive measure but uncomfortable PPEs in foundry units were avoided.Conclusion:  Heat stress in small-scale industry units was found high and there is a high need to develop specific strategies for such vulnerably high heat-exposed groups.
导言:全球变暖可能会影响到某些群体,如在产热行业的工人。由于对这一重要领域的研究有限,本研究旨在探讨室内小规模工厂工人的热应激脆弱性和适应策略。方法:这是一项横断面研究,采用混合方法。研究环境是小型工厂单位。定量部分包括在夏季和冬季对六个轧钢厂和铸造厂进行的环境和生物监测。该研究于2018年11月至2019年5月期间进行。使用便携式湿球温度(WBGT)测量工人的热应激。测量了工人的生理参数。定性部分包括对来自11个单位的工人和主管的深入访谈。结果:轧钢厂和铸造厂夏季和冬季的最高温度均超过职业安全与健康管理局(OSHA)的阈值(27.5℃)。轧钢厂的平均WBGT为31.5℃。轧钢和铸造厂工人的心率和口腔温度的生理测量也超过了阈值水平。这些单元有散热机制,但缺乏单元内部的温度监测机制。作为一种适应性措施,工人们穿着更轻或更少的衣服,但铸造单位避免了不舒服的ppe。结论:小型工业单位存在较高的热应激,有必要针对这些脆弱的高热暴露群体制定针对性的对策。
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引用次数: 0
Subjective Burden and Task Performance during Simulated Long Working Hours 模拟长时间工作的主观负担与任务绩效
Q4 Social Sciences Pub Date : 2023-06-27 DOI: 10.2486/josh.josh-2023-0002-ta
Xinxin Liu, Hiroki Ikeda, Fuyuki Oyama, Yukimitsu Nishimura, Masaya Takahashi
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引用次数: 0
Proposal of Support Application Software to Implement Hazard Identification of Machinery for Small and Medium-Sized Business Sites 支持应用软件实现中小企业场所机械危害识别的建议
Q4 Social Sciences Pub Date : 2023-06-12 DOI: 10.2486/josh.josh-2022-0032-ji
Toshiro Hoshi, Kazu Irisawa, Tetsuya Kimura, Tsuyoshi Saito, K. Hamajima, H. Ikeda
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引用次数: 0
脊髄損傷者用動力付外骨格型機器のプロトタイプ開発 开发用于脊髓损伤者的动力外骨骼装置原型
Q4 Social Sciences Pub Date : 2023-05-22 DOI: 10.2486/josh.josh-2022-0029-ji
H. Oyama, H. Ikeda
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引用次数: 0
事業所のエアロゾル感染予防に向けた調査手法の提案と実証 针对事业所的气溶胶感染预防的调查手法的提案和实证
Q4 Social Sciences Pub Date : 2023-04-29 DOI: 10.2486/josh.josh-2022-0024-cho
Yo Ishigaki, Tatsuo Kato
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引用次数: 0
Proposal of Implementation Support Method and Means for Hazard Identification at the Design Phase of Machinery 机械设计阶段危害识别的实施支持方法和手段建议
Q4 Social Sciences Pub Date : 2023-04-27 DOI: 10.2486/josh.josh-2022-0028-ji
Tsuyoshi Saito, K. Hamajima, H. Ikeda
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引用次数: 0
Evaluation of the knowledge of sun exposure and sun protective measures in healthcare workers 对医务人员日晒知识和防晒措施的评价
Q4 Social Sciences Pub Date : 2023-03-15 DOI: 10.3126/ijosh.v13i2.43305
E. Aryal, P. Shrestha, Sujan Gautam
Introduction: Solar ultraviolet (UV) radiation has a great impact on human life. The sun has always played an important role in Asian culture, so much so, that it is often prayed to as a God. Prolonged sun exposure can cause extensive and chronic harmful effects. Healthcare personnel is supposed to have good knowledge regarding sun protection as they play a key role in society disseminating knowledge to the general public. There are limited data regarding the knowledge of sun protection and sunscreen practice among health care workers.Methods: This descriptive cross-sectional study was carried out from June to October 2020 on healthcare workers (medical staff) in Kathmandu Medical College Teaching Hospital. A questionnaire was distributed to the target study population without disturbing or hampering the healthcare worker’s duty.Results: Out of a total of 264 participants in the study, 84 (31.8%) were male and 180 (68.2%) were female. The knowledge of proper terminology for SPF (Sun Protection Factor) was noted in 196 (74.2%) and 57 (21.6%) agreed that the value of SPF was related to age. No significant difference was noted regarding knowledge about the time of sun exposure for Vitamin D synthesis. No significant differences were found in practices of sunscreen use for purposes of fairness, or prevention of tanning, wrinkle, mole, and skin cancer.Conclusion: A higher level of education was associated with better knowledge and proper abiding practices regarding sunscreen use. As healthcare workers play a key role in distributing information in society, they should be targeted in education campaigns regarding sun exposure and sun protection measures; with these efforts focused more on nurses and medical officers.
太阳紫外线(UV)辐射对人类的生活有很大的影响。太阳在亚洲文化中一直扮演着重要的角色,以至于人们经常把它当作神来祈祷。长时间暴露在阳光下会造成广泛和慢性的有害影响。医护人员在社会上担当重要角色,向市民传播防晒知识,因此他们应具备良好的防晒知识。关于卫生保健工作者的防晒知识和防晒霜实践的数据有限。方法:本描述性横断面研究于2020年6月至10月对加德满都医学院教学医院的医护人员(医务人员)进行。在不干扰或妨碍保健工作者履行职责的情况下,向目标研究人群分发了一份调查问卷。结果:在研究的264名参与者中,84名(31.8%)为男性,180名(68.2%)为女性。有196名(74.2%)及57名(21.6%)市民认识防晒系数(SPF)的正确名词,认为防晒系数与年龄有关。关于维生素D合成的日照时间的知识没有显著差异。在以美白、预防晒黑、皱纹、痣和皮肤癌为目的的防晒霜使用实践中,没有发现显著差异。结论:较高的教育水平与更好的知识和正确的防晒霜使用习惯有关。由于卫生保健工作者在社会传播信息方面发挥着关键作用,他们应该成为关于阳光照射和防晒措施的教育运动的目标;这些努力更多地集中在护士和医务人员身上。
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引用次数: 0
期刊
International Journal of Occupational Safety and Health
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