Pub Date : 2022-12-31DOI: 10.23937/2643-4466/1710039
A. Aziz, Talbi Ghofrane, A. Firas, M. Fatma, W. Ferjaoui, H. Mestiri, B. Rached
{"title":"Morbidity and Mortality in Patients Undergoing Surgery for Hepatocellular Carcinoma","authors":"A. Aziz, Talbi Ghofrane, A. Firas, M. Fatma, W. Ferjaoui, H. Mestiri, B. Rached","doi":"10.23937/2643-4466/1710039","DOIUrl":"https://doi.org/10.23937/2643-4466/1710039","url":null,"abstract":"","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115782490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis of Concussion in a Victim of Road Traffic Accident","authors":"Thivaharan Yalini, Kitulwatteb Indira Deepthi Gamage","doi":"10.23937/2643-4466/1710038","DOIUrl":"https://doi.org/10.23937/2643-4466/1710038","url":null,"abstract":"","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117221452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyponatremia Related To Pericardial Tamponade Caused By Renal Cell Carcinoma: A Rare Cause of Cardiac Tamponade","authors":"Stylianou Vasiliki Vanesa, Kyriakou Avgoustina, Kapetis Lorentzos","doi":"10.23937/2643-4466/1710037","DOIUrl":"https://doi.org/10.23937/2643-4466/1710037","url":null,"abstract":"","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123545151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.23937/2643-4466/1710036
Witkin Steven S, Skupski Daniel, Moron Antonio F, Boester Allison, Linhares Iara M, Forney Larry J
{"title":"Association between the Third Trimester Vaginal Microbiome and Time from Full Cervical Dilation to Delivery: An Exploratory Study","authors":"Witkin Steven S, Skupski Daniel, Moron Antonio F, Boester Allison, Linhares Iara M, Forney Larry J","doi":"10.23937/2643-4466/1710036","DOIUrl":"https://doi.org/10.23937/2643-4466/1710036","url":null,"abstract":"","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122507135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.23937/2643-4466/1710035
Floriani Maiara A, Bessel Marina, Zorzo Isabelle W, Glaeser Andressa B, Grando Rafael Domingos, Rodeghiero Raphael Goveia, Parrini Mohamed Mutlaq, Bastos Gisele Nader, Nasi Luiz Antonio
Background: We do not have detailed evidence on conditions or treatments that act as predictors of hospital outcomes. Objective: To identify the clinical predictors of hospital outcomes in COVID-19 patients and to evaluate the effect of therapeutic’s interventions on length of stay, ICU admission, need for mechanical ventilation (MV) and mortality. Materials and methods: The primary outcome was to assess whether any treatment alone or in combination with standard care, was able to reduce ICU admission, need for MV or mortality. The secondary end points were 1) To know if any single or combined treatment was able to reduce the length of stay in the hospital, MV and ICU, 2) Whether some form of oxygen support prevented MV and 3) Which clinical predictors are relevant for worse outcome. Results: AZM-Corticosteroid and therapeutic anticoagulation when indicated reduced the ICU stay in 1.5 day and MV in 4 days, but when the same combination included HCQ this time increased. For the AZM-Corticosteroid and therapeutic anticoagulation combination the mean ICU length stay was 15.9 days, however when HCQ was present, again the mean ICU time was 40.3 days. The clinical predictors at admission for death were: Age > 65 years, presence of up one comorbidity, pulmonary involvement more than 50%, saturation < 93%, lymphocytes < 900 mm3, D-dimers > 1.250 ng/mL and C-reactive protein (CRP) > 8.0 mg/dL. Conclusion: AZM-Corticosteroids and therapeutic anticoagulation, when indicated, represented a favorable combination for inpatients with COVID-19.Some clinical predictors at admission may help to estimate a higher risk of poor evolution.
{"title":"Clinical Predictors of In-Hospital Outcomes in COVID-19 Patients: A Retrospective Cohort Study","authors":"Floriani Maiara A, Bessel Marina, Zorzo Isabelle W, Glaeser Andressa B, Grando Rafael Domingos, Rodeghiero Raphael Goveia, Parrini Mohamed Mutlaq, Bastos Gisele Nader, Nasi Luiz Antonio","doi":"10.23937/2643-4466/1710035","DOIUrl":"https://doi.org/10.23937/2643-4466/1710035","url":null,"abstract":"Background: We do not have detailed evidence on conditions or treatments that act as predictors of hospital outcomes. Objective: To identify the clinical predictors of hospital outcomes in COVID-19 patients and to evaluate the effect of therapeutic’s interventions on length of stay, ICU admission, need for mechanical ventilation (MV) and mortality. Materials and methods: The primary outcome was to assess whether any treatment alone or in combination with standard care, was able to reduce ICU admission, need for MV or mortality. The secondary end points were 1) To know if any single or combined treatment was able to reduce the length of stay in the hospital, MV and ICU, 2) Whether some form of oxygen support prevented MV and 3) Which clinical predictors are relevant for worse outcome. Results: AZM-Corticosteroid and therapeutic anticoagulation when indicated reduced the ICU stay in 1.5 day and MV in 4 days, but when the same combination included HCQ this time increased. For the AZM-Corticosteroid and therapeutic anticoagulation combination the mean ICU length stay was 15.9 days, however when HCQ was present, again the mean ICU time was 40.3 days. The clinical predictors at admission for death were: Age > 65 years, presence of up one comorbidity, pulmonary involvement more than 50%, saturation < 93%, lymphocytes < 900 mm3, D-dimers > 1.250 ng/mL and C-reactive protein (CRP) > 8.0 mg/dL. Conclusion: AZM-Corticosteroids and therapeutic anticoagulation, when indicated, represented a favorable combination for inpatients with COVID-19.Some clinical predictors at admission may help to estimate a higher risk of poor evolution.","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129734304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-29DOI: 10.23937/2643-4466/1710034
Ž. Babić, M. Vukelić Marković, M. Banic, Barbara Medić
Introduction: A number of complications are known to occur in the course of inflammatory bowel diseases. However, perianal fistulas and fissure can occur with or without active inflammatory bowel disease, occurrence of which prior to the development of ulcerative colitis is a rare occasion. Case presentation: Here we report a case of ulcerative colitis, which was misdiagnosed, treated as a perianal fissure and anal pressure ulcer without recognizing inflammatory bowel disease. Conclusion: In case of anal fistulas and fissures a multidisciplinary approach should be considered, including both surgical and internal medicine professionals.
{"title":"Ulcerative Colitis Presenting as an Anal Fissure in 78-Years-Old Woman","authors":"Ž. Babić, M. Vukelić Marković, M. Banic, Barbara Medić","doi":"10.23937/2643-4466/1710034","DOIUrl":"https://doi.org/10.23937/2643-4466/1710034","url":null,"abstract":"Introduction: A number of complications are known to occur in the course of inflammatory bowel diseases. However, perianal fistulas and fissure can occur with or without active inflammatory bowel disease, occurrence of which prior to the development of ulcerative colitis is a rare occasion. Case presentation: Here we report a case of ulcerative colitis, which was misdiagnosed, treated as a perianal fissure and anal pressure ulcer without recognizing inflammatory bowel disease. Conclusion: In case of anal fistulas and fissures a multidisciplinary approach should be considered, including both surgical and internal medicine professionals.","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"2014 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128586985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-10DOI: 10.23937/2643-4466/1710033
Khan Muhammad Zubair, Zahid Shaheer, F. Sona, Saeed Jamaluddin, M FigueredoVincent, K. Steven, Kilcoyne James
COVID-19 virus does not directly affect the heart. The virus can cause systematic inflammation that can lead to severe cardiac complications like uncontrolled atrial fibrillation (AF), which carries high mortality among patients. We present a case of an 82-year-old female from nursing home with advanced dementia and multiple comorbidities. She initially screened negative for COVID-19 in the nursing home, however her repeat test was positive. Soon after admission she developed progressive, hypoxic respiratory failure and was subsequently diagnosed with ARDS and required endotracheal intubation. The patient was found to have uncontrolled AF on telemetry monitoring. Initially, intravenous calcium channel blockers were unsuccessful in controlling her heart rate, thus this was later changed to intravenous amiodarone. The patient was successfully extubated on day 15 and transferred to the general medical floor on antiarrhythmic medication for AF.
{"title":"Management of Uncontrolled Atrial Fibrillation in COVID Patient","authors":"Khan Muhammad Zubair, Zahid Shaheer, F. Sona, Saeed Jamaluddin, M FigueredoVincent, K. Steven, Kilcoyne James","doi":"10.23937/2643-4466/1710033","DOIUrl":"https://doi.org/10.23937/2643-4466/1710033","url":null,"abstract":"COVID-19 virus does not directly affect the heart. The virus can cause systematic inflammation that can lead to severe cardiac complications like uncontrolled atrial fibrillation (AF), which carries high mortality among patients. We present a case of an 82-year-old female from nursing home with advanced dementia and multiple comorbidities. She initially screened negative for COVID-19 in the nursing home, however her repeat test was positive. Soon after admission she developed progressive, hypoxic respiratory failure and was subsequently diagnosed with ARDS and required endotracheal intubation. The patient was found to have uncontrolled AF on telemetry monitoring. Initially, intravenous calcium channel blockers were unsuccessful in controlling her heart rate, thus this was later changed to intravenous amiodarone. The patient was successfully extubated on day 15 and transferred to the general medical floor on antiarrhythmic medication for AF.","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"5 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127831327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-02DOI: 10.23937/2643-4466/1710025
Namuduri Rama P, G. Mihir, Tan Soo Kim Lim
Extraocular sebaceous carcinoma is an uncommon malignant tumor that usually affects the head and neck. Despite being rich in sebaceous glands, vulvar sebaceous carcinoma is extremely rare. We report a case of vulvar sebaceous carcinoma in a 64-year-old woman that presented as an asymptomatic nodule and was successfully treated by wide local excision. The number of reported cases of vulvar sebaceous carcinoma is very small, more cases need to be collected in order to identify prognostic factors and appropriate management modalities.
{"title":"Sebaceous Carcinoma of the Vulva: Case Report and Review of Literature","authors":"Namuduri Rama P, G. Mihir, Tan Soo Kim Lim","doi":"10.23937/2643-4466/1710025","DOIUrl":"https://doi.org/10.23937/2643-4466/1710025","url":null,"abstract":"Extraocular sebaceous carcinoma is an uncommon malignant tumor that usually affects the head and neck. Despite being rich in sebaceous glands, vulvar sebaceous carcinoma is extremely rare. We report a case of vulvar sebaceous carcinoma in a 64-year-old woman that presented as an asymptomatic nodule and was successfully treated by wide local excision. The number of reported cases of vulvar sebaceous carcinoma is very small, more cases need to be collected in order to identify prognostic factors and appropriate management modalities.","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"55 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141207045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-26DOI: 10.23937/2643-4466/1710020
P. Jun, S. Vishal
Langerhans Cell Histiocytosis (LCH) is a rare disorder with an incident of 1.8 cases per 1,000,000. It involves granulomatous deposits in multiple organs, leading to a wide variety of manifestations such as bone lesions, pulmonary nodules, pituitary lesions, and skin lesions. With mucocutaneous manifestation, it is often diagnosed in childhood, typically making LCH a childhood disease. However, due to the involvement of multiple organ systems and variable clinical courses, if not diagnosed during childhood, the patients with LCH often suffer from delayed diagnosis and treatments as adults. choroid glioma, and metastatic lesion. Given the concerning changes involving the pituitary as shown on radiographic findings, serum levels of the following pituitary hormones were obtained: FSH, LH, ACTH stimulation test, TSH, prolactin, IGF-1. The results came back with abnormally low FSH at 0.4 mIU/mL (reference range for male is 0.9 11.9 mIU/mL), LH < 0.1 mIU/mL (1.5-9.3 mIU/mL for male), ACTH stimulation test with a peak cortisol level at 14.8 ug/dL (normal response consists of at least 7 mcg/dL from baseline and a peak of *Corresponding author: Jun Park, St. Vincent Hospital Indianapolis, Indiana, USA CaSe RePoRt
{"title":"Clinical Conundrums in Diagnosis and Management of Multisystem Langerhans Cell Histiocytosis","authors":"P. Jun, S. Vishal","doi":"10.23937/2643-4466/1710020","DOIUrl":"https://doi.org/10.23937/2643-4466/1710020","url":null,"abstract":"Langerhans Cell Histiocytosis (LCH) is a rare disorder with an incident of 1.8 cases per 1,000,000. It involves granulomatous deposits in multiple organs, leading to a wide variety of manifestations such as bone lesions, pulmonary nodules, pituitary lesions, and skin lesions. With mucocutaneous manifestation, it is often diagnosed in childhood, typically making LCH a childhood disease. However, due to the involvement of multiple organ systems and variable clinical courses, if not diagnosed during childhood, the patients with LCH often suffer from delayed diagnosis and treatments as adults. choroid glioma, and metastatic lesion. Given the concerning changes involving the pituitary as shown on radiographic findings, serum levels of the following pituitary hormones were obtained: FSH, LH, ACTH stimulation test, TSH, prolactin, IGF-1. The results came back with abnormally low FSH at 0.4 mIU/mL (reference range for male is 0.9 11.9 mIU/mL), LH < 0.1 mIU/mL (1.5-9.3 mIU/mL for male), ACTH stimulation test with a peak cortisol level at 14.8 ug/dL (normal response consists of at least 7 mcg/dL from baseline and a peak of *Corresponding author: Jun Park, St. Vincent Hospital Indianapolis, Indiana, USA CaSe RePoRt","PeriodicalId":346614,"journal":{"name":"International Archives of Internal Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129012729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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