Pub Date : 2018-11-01DOI: 10.15406/mojddt.2018.02.00066
I. Umaru, B. Samling, H. Umaru
Objective: The study aimed to identify the phytochemical composition of Leucaena leococephala leaf and evaluate the antimicrobial potential of the essential oil from the leaf. Material and Methods: The sample was subjected to Clevenger apparatus to extract the oil. The essential oil was characterized by chromatography method (GC-MS). The GC-MS was performed on Perkin Elmer gas chromatography model Clarus 680 equipped with HP-5 fused capillary column (5%) phenylmethyl polysiloxane stationary phase with 30m length, 0.25µm of film thickness and 0.25oc and 280oc respectively. Antibacterial activity using Agar Disc Method. Result: The result obtained from the GC-MS presented thirty phytochemicals of which Neophytadiene (9.48%), Octadecane (3.15%), 1-Octadecyne (3.85%), Phytol (52.51%) and Hexacosane (7.26%) are major. The antibacterial potential activities were observed in various ways with zone of inhibition diameters ranging from 0.70±0.00mm to1.27±0.06mm for staphylococcus aureus and Klebsielia pneumonia respectively among the six-concentration selected (25, 50, 100, 250, 500, and 1000ppm). Conclusion: It is investigated in this present studies that Leucaena leococephala essential oil can be utilized against the management of antibacterial diseases particularly Klebsielia pneumonia and Staphylococcus aureusas well as used in the Pharmaceutical and Cosmetics industry.
{"title":"Phytochemical screening of Leucaena leucocephala leaf essential oil and its antibacterial potentials","authors":"I. Umaru, B. Samling, H. Umaru","doi":"10.15406/mojddt.2018.02.00066","DOIUrl":"https://doi.org/10.15406/mojddt.2018.02.00066","url":null,"abstract":"Objective: The study aimed to identify the phytochemical composition of Leucaena leococephala leaf and evaluate the antimicrobial potential of the essential oil from the leaf. Material and Methods: The sample was subjected to Clevenger apparatus to extract the oil. The essential oil was characterized by chromatography method (GC-MS). The GC-MS was performed on Perkin Elmer gas chromatography model Clarus 680 equipped with HP-5 fused capillary column (5%) phenylmethyl polysiloxane stationary phase with 30m length, 0.25µm of film thickness and 0.25oc and 280oc respectively. Antibacterial activity using Agar Disc Method. Result: The result obtained from the GC-MS presented thirty phytochemicals of which Neophytadiene (9.48%), Octadecane (3.15%), 1-Octadecyne (3.85%), Phytol (52.51%) and Hexacosane (7.26%) are major. The antibacterial potential activities were observed in various ways with zone of inhibition diameters ranging from 0.70±0.00mm to1.27±0.06mm for staphylococcus aureus and Klebsielia pneumonia respectively among the six-concentration selected (25, 50, 100, 250, 500, and 1000ppm). Conclusion: It is investigated in this present studies that Leucaena leococephala essential oil can be utilized against the management of antibacterial diseases particularly Klebsielia pneumonia and Staphylococcus aureusas well as used in the Pharmaceutical and Cosmetics industry.","PeriodicalId":346758,"journal":{"name":"MOJ Drug Design Development & Therapy","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114066485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-02DOI: 10.15406/mojddt.2018.02.00032
Tarik Ainane, A. Ayoub, K. Fatima, Talbi Mohammed, Charaf Sanaa, Elabboubi Meriem, El Kouali Mhamed, Bricha Mohamed Reda, A. Hassan, Cherroud Sanaa
Aromatic plants produce essential oils as secondary metabolites, but their exact role in the processes of plant life remains unknown.1 Some authors believe that the plant uses oil to repel or attract insects, in the latter case, to promote pollination. Others consider the oil as an energetic source, facilitating certain chemical reactions, conserve the humidity of plants in desert climates.2 Some essential oils are used for the defense of plants against herbivores, insects and microorganisms.3
{"title":"Chemical characterizations of the aromatic compositions of two citrus species: citrus aurantium and citrus reticulata","authors":"Tarik Ainane, A. Ayoub, K. Fatima, Talbi Mohammed, Charaf Sanaa, Elabboubi Meriem, El Kouali Mhamed, Bricha Mohamed Reda, A. Hassan, Cherroud Sanaa","doi":"10.15406/mojddt.2018.02.00032","DOIUrl":"https://doi.org/10.15406/mojddt.2018.02.00032","url":null,"abstract":"Aromatic plants produce essential oils as secondary metabolites, but their exact role in the processes of plant life remains unknown.1 Some authors believe that the plant uses oil to repel or attract insects, in the latter case, to promote pollination. Others consider the oil as an energetic source, facilitating certain chemical reactions, conserve the humidity of plants in desert climates.2 Some essential oils are used for the defense of plants against herbivores, insects and microorganisms.3","PeriodicalId":346758,"journal":{"name":"MOJ Drug Design Development & Therapy","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132026070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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