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Demineralized freeze-dried bone allograft with/without i-Platelet-rich fibrin in 3 wall intrabony defects 富含/不富含 i-Platelet 纤维蛋白的脱矿物质冻干骨异体移植治疗 3 壁骨内缺损
Q4 Dentistry Pub Date : 2024-03-10 DOI: 10.20396/bjos.v23i00.8670338
Rinnu Mathew, Anuradha Bhatsange
Demineralized freeze-dried bone allograft (DFDBA) contains bone morphogenetic proteins (BMPs), hence is osteoinductive. Autologous platelet concentrates exhibit a higher quantity of growth factors. Both these biomaterials aid in bone regeneration when placed in three-wall intrabony defects. However, their efficacy when used alone and in conjugation is not clear. Aim: To assess clinical and radiographic efficacy of injectable platelet-rich fibrin (i-PRF) with microsurgical access flap in the treatment of three-wall intrabony defects in chronic periodontitis patients. Methods: Thirty sites with three-wall intrabony defects were randomly assigned to control and test group by computer generated method. The test group obtained i-PRF mixed with DFDBA while the control group received only DFDBA. Clinical parameters such as site-specific Plaque index (PI), Radiographic intrabony defect depth (IBDD), modified- Sulcular bleeding index (mSBI), Clinical attachment level (CAL), and Probing pocket depth (PPD) were measured at baseline, three and six months. Results: Intragroup comparison within the control group and test group exhibited statistically highly significant variation of mean PI, mSBI, PPD, CAL, and IBDD score from baseline to 3 months and from 3-6 months (p<0.001). However, intergroup comparison demonstrated no statistically significant variation of mean IBDD at all 3 intervals (p>0.05). Conclusion: i-PRF combined with DFDBA enhanced the radiographic and clinical parameters as opposed to DFDBA alone. The role of i-PRF is promising in its capacity for easy obtainability and increased potential to aid in regeneration.
脱矿物质冻干骨异体移植(DFDBA)含有骨形态发生蛋白(BMPs),因此具有骨诱导作用。自体血小板浓缩物含有更多的生长因子。当将这两种生物材料置于三壁骨内缺损处时,都有助于骨再生。然而,它们单独使用或联合使用时的功效尚不明确。目的:评估注射用富血小板纤维蛋白(i-PRF)配合显微外科入路皮瓣治疗慢性牙周炎患者三壁内骨缺损的临床和影像学疗效。方法:通过计算机生成方法将 30 个三壁牙内缺损部位随机分配到对照组和试验组。试验组使用 i-PRF 混合 DFDBA,对照组仅使用 DFDBA。分别在基线期、三个月和六个月时测量临床参数,如特定部位的斑块指数(PI)、X光片显示的牙本质内缺损深度(IBDD)、改良肌肉出血指数(mSBI)、临床附着水平(CAL)和探诊袋深度(PPD)。结果对照组和测试组的组内比较显示,从基线到 3 个月以及 3-6 个月期间,平均 PI、mSBI、PPD、CAL 和 IBDD 分数的差异在统计学上非常显著(P0.05)。结论:与单独使用 DFDBA 相比,i-PRF 联合 DFDBA 可提高放射学和临床参数。i-PRF 易于获得,而且在帮助再生方面具有更大的潜力,因此其作用前景广阔。
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引用次数: 0
Evaluation of characteristics of periodontal probes 评估牙周探针的特性
Q4 Dentistry Pub Date : 2024-03-10 DOI: 10.20396/bjos.v23i00.8670401
A. C. Kovalik, Alessandra Carla Sousa Girardi, Naiara Vendrami, Fabio André dos Santos
Aim: This study aimed to evaluate the millimeter distances and active tip diameters of different periodontal probes. Methods: Two types of periodontal probes were analyzed (North Carolina (15-UNC) and PCP-12). Two manufacturers were selected for each probe type. Digital images of the probes were obtained and the distances were measured using a software program. The diameter of the active tip was measured using a digital caliper. Both variables were measured by two trained and calibrated examiners. The data were analyzed using the Bland-Altman method and two-way ANOVA with Tukey’s post-hoc test. Statistical significance was set at p<0.05. Results: A comparison of measurements between the 15UNC and PCP-12 probes showed a significant difference in all millimeter markings. The 15-UNC probe showed differences between the 3 and 12 mm markings. The PCP-12 probe only showed differences between the marks at the 12 mm mark. The 15-UNC probe had a similar active tip diameter between the two manufacturers. The PCP-12 probe showed a significant difference between the two manufacturers. Both types of probes had similar active tip diameters when compared by the two manufacturers. Conclusion: There was no standardization in relation to millimeter marks and tip diameters of the two types of periodontal probes produced by the two different manufacturers. The probe types exhibited little variability.
目的:本研究旨在评估不同牙周探针的毫米距离和活动尖端直径。方法分析了两种牙周探针(北卡罗来纳州(15-UNC)和 PCP-12)。每种探针选择了两个制造商。获得探针的数字图像,并使用软件程序测量距离。使用数字卡尺测量活动尖端的直径。两个变量均由两名经过培训和校准的检查员测量。数据分析采用 Bland-Altman 方法和双向方差分析,并进行 Tukey 后检验。统计显著性设定为 p<0.05。结果对 15UNC 和 PCP-12 探头的测量结果进行比较后发现,它们在所有毫米标记上都存在显著差异。15UNC 探头在 3 毫米和 12 毫米标记之间存在差异。而 PCP-12 探头仅在 12 毫米刻度处的刻度之间存在差异。两家制造商生产的 15-UNC 探头的有效针尖直径相似。PCP-12 探头在两个制造商之间存在明显差异。两家制造商生产的两种探针的有效针尖直径相似。结论:两个不同制造商生产的两种牙周探针的毫米标记和尖端直径没有标准化。探针类型的差异性很小。
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引用次数: 0
Color variation of composite resins in relation to the Vita Classical shade guide 复合树脂的颜色变化与 Vita 经典色调指南的关系
Q4 Dentistry Pub Date : 2024-03-10 DOI: 10.20396/bjos.v23i00.8670869
João Vitor Andrade Denadai, R. Zimmer, E. Reston, G. Arossi
Aim: The aim of this study was to verify the color variation between different composite resins and the Vita Classical Shade Guide. Methods: Two-millimeter thickness samples were made (n = 6) from eight commercial brands of composite resin (shade A2): Charisma (Kulzer), Forma (Ultradent), Harmonize (Kerr), Luna (SDI), Opallis (FGM), Oppus Bulk Fill (FGM), Vittra (FGM) and Filtek Z250 XT (3M ESPE). Specimens were stored in distilled water for 7 days and then polished. Color measurements of samples and A2 shade of the Vita Classical Shade Guide were performed using the Vita Easy Shade Advance 4.0 spectrophotometer on a black background. Color variations were calculated using the CIEDE2000 formula, considering values ≥0.81 being noticeable by the human eye and ≥1.77 being clinically unacceptable. Results were statistically analyzed with a 5% significance level. Results: Color variation (ΔE) of composite (E1 ) compared to the Vita Classical Shade Guide (E0 ) was greater than clinically acceptable for all the materials evaluated in this study. Forma (ΔE=2.08 ± sd=0.47) and Filtek Z250 XT (2.50 ± 0.20) had the smallest amount of color variation values found in the results. Harmonize (3.32 ± 0.63) presented values similar to Filtek Z250 XT, but it was worse than Forma. Vittra (3.51 ± 0.28), Charisma (3.80 ± 0.20), Opallis (4.24 ± 0.30) and Luna (5.67 ± 0.20) did not differ among each other and presented higher color variation than Forma, Filtek Z350XT and Harmonize. Oppus Bulk Fill (13.94 ± 1.12) was the composite with the greatest color variation. Conclusions: The findings in this study show that attention should be taken when using the Vita Color Shade Guide for composite shade selection.
目的:本研究旨在验证不同复合树脂与 Vita 经典色调指南之间的色差。方法:从八种商业品牌的复合树脂中制作两毫米厚度的样品(n = 6):从八种商业品牌的复合树脂(色调 A2)中提取厚度为两毫米的样品(n = 6):Charisma(Kulzer)、Forma(Ultradent)、Harmonize(Kerr)、Luna(SDI)、Opallis(FGM)、Oppus Bulk Fill(FGM)、Vittra(FGM)和 Filtek Z250 XT(3M ESPE)。样品在蒸馏水中存放 7 天,然后进行抛光。使用 Vita Easy Shade Advance 4.0 分光光度计在黑色背景上测量样品的颜色和《伟特经典色调指南》的 A2 色调。色差采用 CIEDE2000 公式进行计算,认为≥0.81 的值为人眼可察觉值,≥1.77 的值为临床不可接受值。结果以 5%的显著性水平进行统计分析。结果与《Vita 经典色调指南》(E0)相比,本研究评估的所有材料的复合材料(E1)色差(ΔE)均大于临床可接受水平。结果发现,Forma(ΔE=2.08 ± sd=0.47)和 Filtek Z250 XT(2.50 ± 0.20)的色差值最小。Harmonize(3.32 ± 0.63)的数值与 Filtek Z250 XT 相似,但比 Forma 差。Vittra (3.51 ± 0.28)、Charisma (3.80 ± 0.20)、Opallis (4.24 ± 0.30) 和 Luna (5.67 ± 0.20)之间没有差异,颜色变化值高于 Forma、Filtek Z350XT 和 Harmonize。Oppus Bulk Fill(13.94 ± 1.12)是颜色变化最大的复合材料。结论:这项研究结果表明,在使用《伟特色调指南》选择复合色调时应注意以下几点。
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引用次数: 0
Self-perceived oral health 自我感觉口腔健康
Q4 Dentistry Pub Date : 2024-03-05 DOI: 10.20396/bjos.v23i00.8673318
Solange Schroeder Corrêa, P. Martinello, D. E. Carneiro, Alfonso Sánchez-Ayala, N. H. Campanha
Aim: This study aimed to investigate the relationship between self-perceived oral health and the prosthetic status of individuals who seek care in prosthodontics clinics. Methods: Self-perceived oral health was analyzed through the Geriatric Oral Health Assessment Index (GOHAI). Abutment tooth mobility was assessed, and denture status was determined by clinical assessment of stability, retention, occlusal balance, vertical dimension, and integrity of dentures. The frequency of individuals in each variable was determined for the low and very low GOHAI conditions. Chi-square, Pearson, and stepwise logistic regression tests were used for the statistical analyses (α = 0.05). Results: Ninety wearers of removable dentures with a mean age of 55.1±9.1 years were evaluated. None of the variables was related to GOHAI values (p > 0.05). The regression analysis showed that age predicts (p = 0.006) the variation of GOHAI conditions (OR = 0.924, CI = 0.873- 0.978), showing only 7.6% protective effect against very low GOHAI. Unsatisfactory stability showed the opposite effect (p = 0.034) and the individuals with this characteristic are more likely (OR = 3.055) to have very low GOHAI scores (CI = 1.085- 8.602). Conclusions: The self-perceived oral health of wearers of removable dentures worsens with age and unsatisfactory stability of dentures.
目的:本研究旨在调查口腔修复诊所就诊者的自我感觉口腔健康与修复状况之间的关系。研究方法通过老年口腔健康评估指数(GOHAI)分析自我感觉的口腔健康状况。对基牙活动度进行评估,并通过临床评估假牙的稳定性、固位、咬合平衡、垂直度和完整性来确定假牙状态。在低GOHAI和极低GOHAI条件下,确定每个变量的个体频率。统计分析采用了卡方检验、皮尔逊检验和逐步逻辑回归检验(α = 0.05)。结果接受评估的 90 名活动义齿佩戴者的平均年龄为 55.1±9.1 岁。没有一个变量与 GOHAI 值相关(P > 0.05)。回归分析表明,年龄可预测(p = 0.006)GOHAI 条件的变化(OR = 0.924,CI = 0.873-0.978),对极低的 GOHAI 仅有 7.6% 的保护作用。稳定性不理想则显示出相反的效果(p = 0.034),具有这种特征的人更有可能(OR = 3.055)获得极低的 GOHAI 分数(CI = 1.085-8.602)。结论活动假牙佩戴者的自我感觉口腔健康状况会随着年龄增长和假牙稳定性不理想而恶化。
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引用次数: 0
Burnout syndrome in peruvian dental students 秘鲁牙科学生的职业倦怠综合征
Q4 Dentistry Pub Date : 2024-03-04 DOI: 10.20396/bjos.v23i00.8671300
Ana Elizabeth Ramírez-López, A. Asmat-Abanto
Aim: Burnout syndrome describes the state of long-term physical, emotional and mental exhaustion related to work. This syndrome can cause health problems related to stress, insomnia, cardiovascular and musculoskeletal diseases, including an increase in alcohol consumption and drug use. It is important to recognize the presence of the initial signs of this syndrome, therefore this study aimed to determine the prevalence of the burnout syndrome in peruvian dental students. Methods: The study was observational, cross-sectional, and descriptive. It was carried out from September to November 2018, and it included a total of 154 dental students of four universities of La Libertad region, surveyed by census method. Three were private universities and one was public. Burnout was evaluated through the Maslach Burnout Student Survey Questionnaire (MBI-SS). The results were presented in absolute and percentage frequencies, as well as confidence intervals, using double-entry tables. Results: It was found that 24.68% of the students (24.71% in male students and 24.64% in female students) presented burnout syndrome. The public university of Trujillo presented the highest percentage of affected students (47.37%). A prevalence of 53,90% of emotional exhaustion was also found among the students under evaluation. Conclusions: Almost a quarter of the students surveyed presented burnout. It was also observed that the public University of Trujillo had a higher percentage of burnout than the three private ones. The percentage of prevalence of the burnout syndrome according to sex was similar. However according to dimensions, emotional exhaustion presented the highest percentage.
目的:职业倦怠综合症描述的是与工作有关的长期身体、情感和精神疲惫状态。这种综合征可导致与压力、失眠、心血管和肌肉骨骼疾病有关的健康问题,包括饮酒和吸毒的增加。因此,本研究旨在确定倦怠综合征在秘鲁牙科学生中的流行率。研究方法本研究为观察性、横断面和描述性研究。研究于2018年9月至11月进行,通过普查方法共调查了拉利伯塔德地区四所大学的154名牙科学生。其中三所为私立大学,一所为公立大学。倦怠感通过马斯拉赫学生倦怠感调查问卷(MBI-SS)进行评估。结果以绝对频率和百分比频率以及置信区间的形式,通过复式表格呈现。结果显示结果发现,24.68% 的学生(男生为 24.71%,女生为 24.64%)患有职业倦怠综合症。特鲁希略公立大学受影响学生的比例最高(47.37%)。在接受评估的学生中,情绪衰竭的发生率也达到了 53.90%。结论近四分之一的受访学生出现了职业倦怠。此外,还发现特鲁希略公立大学的职业倦怠比例高于三所私立大学。不同性别的职业倦怠综合症发生率相似。然而,从不同维度来看,情感衰竭的比例最高。
{"title":"Burnout syndrome in peruvian dental students","authors":"Ana Elizabeth Ramírez-López, A. Asmat-Abanto","doi":"10.20396/bjos.v23i00.8671300","DOIUrl":"https://doi.org/10.20396/bjos.v23i00.8671300","url":null,"abstract":"Aim: Burnout syndrome describes the state of long-term physical, emotional and mental exhaustion related to work. This syndrome can cause health problems related to stress, insomnia, cardiovascular and musculoskeletal diseases, including an increase in alcohol consumption and drug use. It is important to recognize the presence of the initial signs of this syndrome, therefore this study aimed to determine the prevalence of the burnout syndrome in peruvian dental students. Methods: The study was observational, cross-sectional, and descriptive. It was carried out from September to November 2018, and it included a total of 154 dental students of four universities of La Libertad region, surveyed by census method. Three were private universities and one was public. Burnout was evaluated through the Maslach Burnout Student Survey Questionnaire (MBI-SS). The results were presented in absolute and percentage frequencies, as well as confidence intervals, using double-entry tables. Results: It was found that 24.68% of the students (24.71% in male students and 24.64% in female students) presented burnout syndrome. The public university of Trujillo presented the highest percentage of affected students (47.37%). A prevalence of 53,90% of emotional exhaustion was also found among the students under evaluation. Conclusions: Almost a quarter of the students surveyed presented burnout. It was also observed that the public University of Trujillo had a higher percentage of burnout than the three private ones. The percentage of prevalence of the burnout syndrome according to sex was similar. However according to dimensions, emotional exhaustion presented the highest percentage.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140265427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of clinical and laboratory techniques of cementation on the assessment of marginal and internal fit of prosthetic elements 临床和实验室粘接技术对评估修复体边缘和内部密合度的影响
Q4 Dentistry Pub Date : 2024-01-29 DOI: 10.20396/bjos.v23i00.8670950
Carolina Chaves Pinto, Leonardo André Lins da Silva, C. A. A. Licurci, Antonio Canabarro
Aim: The aim of this in vitro study was to compare machine and manual cementation of prosthetic elements by measuring internal and marginal fits. Methods: Eighteen anatomic prefabricated abutments were used to manufacture zirconia copings in the Ceramill (n=9) and Lava systems (n=9). The copings were cemented with a fluid consistency addition silicone using a machine (n=18) and manually (n=18) according to the replica technique. They were then cut in the buccal-palatal and mesial-distal directions. The film thickness was photographed using an optical microscope and measured in the internal and marginal regions. The data collected were analyzed by repeated measures ANOVA and Bonferroni’s multiple comparison test (∂=.05). The Bland-Altman test was performed to evaluate the agreement between the methods. Results: In the evaluation of the internal and marginal misfits, the mean values observed for the cementation performed with the aid of a machine and manually, were as follows: angular regions, 76.7 μm and 76.2 μm; linear regions, 60.6 μm and 60.7 μm; incisal region, 144.8 μm and 145.2 μm; marginal region, 40.1 μm and 40.2 μm; and overall mean, 80.4 μm and 80.6 μm, respectively. No significant differences were found between the 2 methods, for any of regions and systems (P>.05). The Bland-Altman test showed agreement between the methods (P>.05) and that the limits of agreement found were clinically acceptable. Conclusions: Within the limitations of this in vitro study, we can conclude that cementation using manual techniques or mechanical aid produces the same cement films.
目的:这项体外研究的目的是通过测量内部和边缘的密合度,比较机器和人工粘接修复体的效果。研究方法在 Ceramill(9 个)和 Lava(9 个)系统中使用 18 个解剖预制基台制作氧化锆修复体。根据复制技术,使用机器(18 个)和手工(18 个)用稠度较高的添加硅酮粘结基台。然后在颊-腭和中-远侧方向进行切割。使用光学显微镜拍摄并测量内部和边缘区域的薄膜厚度。收集的数据采用重复测量方差分析和 Bonferroni 多重比较检验(∂=.05)进行分析。采用 Bland-Altman 检验来评估两种方法之间的一致性。结果在内侧和边缘错位的评估中,借助机器和人工进行粘接的平均值如下:角区,分别为 76.7 μm 和 76.2 μm;线区,分别为 60.6 μm 和 60.7 μm;切缘区,分别为 144.8 μm 和 145.2 μm;边缘区,分别为 40.1 μm 和 40.2 μm;总体平均值,分别为 80.4 μm 和 80.6 μm。两种方法在任何区域和系统中都没有发现明显差异(P>.05)。Bland-Altman 检验显示,两种方法的结果一致(P>.05),且一致程度在临床上是可以接受的。结论在这项体外研究的局限性范围内,我们可以得出结论,使用人工技术或机械辅助进行骨水泥粘接所产生的骨水泥膜是相同的。
{"title":"Effect of clinical and laboratory techniques of cementation on the assessment of marginal and internal fit of prosthetic elements","authors":"Carolina Chaves Pinto, Leonardo André Lins da Silva, C. A. A. Licurci, Antonio Canabarro","doi":"10.20396/bjos.v23i00.8670950","DOIUrl":"https://doi.org/10.20396/bjos.v23i00.8670950","url":null,"abstract":"Aim: The aim of this in vitro study was to compare machine and manual cementation of prosthetic elements by measuring internal and marginal fits. Methods: Eighteen anatomic prefabricated abutments were used to manufacture zirconia copings in the Ceramill (n=9) and Lava systems (n=9). The copings were cemented with a fluid consistency addition silicone using a machine (n=18) and manually (n=18) according to the replica technique. They were then cut in the buccal-palatal and mesial-distal directions. The film thickness was photographed using an optical microscope and measured in the internal and marginal regions. The data collected were analyzed by repeated measures ANOVA and Bonferroni’s multiple comparison test (∂=.05). The Bland-Altman test was performed to evaluate the agreement between the methods. Results: In the evaluation of the internal and marginal misfits, the mean values observed for the cementation performed with the aid of a machine and manually, were as follows: angular regions, 76.7 μm and 76.2 μm; linear regions, 60.6 μm and 60.7 μm; incisal region, 144.8 μm and 145.2 μm; marginal region, 40.1 μm and 40.2 μm; and overall mean, 80.4 μm and 80.6 μm, respectively. No significant differences were found between the 2 methods, for any of regions and systems (P>.05). The Bland-Altman test showed agreement between the methods (P>.05) and that the limits of agreement found were clinically acceptable. Conclusions: Within the limitations of this in vitro study, we can conclude that cementation using manual techniques or mechanical aid produces the same cement films.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140488515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D radiotherapy in the parotid gland and its dosimetric relationship with salivary flow and quality of life in patients with head and neck cancer 腮腺三维放射治疗及其与头颈部癌症患者唾液流量和生活质量的剂量关系
Q4 Dentistry Pub Date : 2024-01-29 DOI: 10.20396/bjos.v23i00.8666798
Ana Waleska Pessôa Barros de Aguiar, L. N. Lins, Ana Luíza Fassizoli da Fonte, Raylane Farias de Albuquerque, J. Leão, Igor Henrique Morais Silva
Aim: Hyposalivation and dry mouth affect the quality of life in patients with Head and Neck Cancer, who did the treatment with radiotherapy. Thus this study has the objective to evaluate the dosimetric relationship between 3D radiotherapy and changes in salivary flow, xerostomia and quality of life in patients with head and neck cancer according to the volume of the irradiated parotid gland. Methods: 23 patients with cancer in the head and neck area and in need of 3D radiotherapy were followed up during radiotherapy treatment, and the parotid gland (PG) design was also performed in radiotherapy planning. Questionnaires were carried out to determine xerostomia and quality of life, while the salivary flow was determined through calculations regarding the collection and weighing of saliva. Such data were collected in three moments: before the beginning of the radiotherapy treatment (D0), in the middle of the treatment (D1) and at the end of it (D2). The numerical variables are represented by measures of central tendency and measures of dispersion. Results: when associating the salivary flow, the xerostomia questionnaire and the OHIP-14, a statistically significant difference was found (p-value <0.001), as well as when comparing some volumes of irradiated PG with the OHIP-14. However, no relationship was found between dosimetric data, xerostomia and hyposalivation. Conclusion: patients undergoing 3D radiotherapy for malignant neoplasms in the head and neck region had decreased salivary flow, increased complaints of dry mouth and decreased quality of life. However, it was not possible to establish a statistically significant correlation between these findings and the volumes of irradiated parotids.
目的:唾液分泌过少和口干会影响接受放疗的头颈部癌症患者的生活质量。因此,本研究旨在根据腮腺受照射的体积,评估三维放疗与头颈部癌症患者唾液流量变化、口干和生活质量之间的剂量关系。方法:在放疗期间对23名需要接受三维放疗的头颈部癌症患者进行随访,并在放疗计划中对腮腺(PG)进行设计。调查问卷用于确定口腔干燥症和生活质量,唾液流量则通过计算唾液的收集和称重来确定。这些数据在三个时刻收集:放疗开始前(D0)、放疗中期(D1)和放疗结束时(D2)。数字变量用中心倾向和离散度量来表示。结果:在将唾液流量、口腔干燥症问卷和 OHIP-14 联系起来时,发现了统计学上的显著差异(P 值<0.001),在将照射 PG 的某些体积与 OHIP-14 进行比较时,也发现了显著差异。然而,在剂量数据、口干和唾液分泌过少之间没有发现任何关系。结论:接受头颈部恶性肿瘤三维放射治疗的患者唾液流量减少,口干的主诉增多,生活质量下降。然而,这些结果与受照射腮腺的体积之间无法建立具有统计学意义的相关性。
{"title":"3D radiotherapy in the parotid gland and its dosimetric relationship with salivary flow and quality of life in patients with head and neck cancer","authors":"Ana Waleska Pessôa Barros de Aguiar, L. N. Lins, Ana Luíza Fassizoli da Fonte, Raylane Farias de Albuquerque, J. Leão, Igor Henrique Morais Silva","doi":"10.20396/bjos.v23i00.8666798","DOIUrl":"https://doi.org/10.20396/bjos.v23i00.8666798","url":null,"abstract":"Aim: Hyposalivation and dry mouth affect the quality of life in patients with Head and Neck Cancer, who did the treatment with radiotherapy. Thus this study has the objective to evaluate the dosimetric relationship between 3D radiotherapy and changes in salivary flow, xerostomia and quality of life in patients with head and neck cancer according to the volume of the irradiated parotid gland. Methods: 23 patients with cancer in the head and neck area and in need of 3D radiotherapy were followed up during radiotherapy treatment, and the parotid gland (PG) design was also performed in radiotherapy planning. Questionnaires were carried out to determine xerostomia and quality of life, while the salivary flow was determined through calculations regarding the collection and weighing of saliva. Such data were collected in three moments: before the beginning of the radiotherapy treatment (D0), in the middle of the treatment (D1) and at the end of it (D2). The numerical variables are represented by measures of central tendency and measures of dispersion. Results: when associating the salivary flow, the xerostomia questionnaire and the OHIP-14, a statistically significant difference was found (p-value <0.001), as well as when comparing some volumes of irradiated PG with the OHIP-14. However, no relationship was found between dosimetric data, xerostomia and hyposalivation. Conclusion: patients undergoing 3D radiotherapy for malignant neoplasms in the head and neck region had decreased salivary flow, increased complaints of dry mouth and decreased quality of life. However, it was not possible to establish a statistically significant correlation between these findings and the volumes of irradiated parotids.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140488375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of cyclooxigenase in dentistry 环氧化酶在牙科中的重要性
Q4 Dentistry Pub Date : 2024-01-29 DOI: 10.20396/bjos.v23i00.8671181
Sara Delgadillo Barrera, Lilia Jadith Bernal Cepeda, Jaime Eduardo Castellanos Parras
Aim: Cyclooxygenase enzymes (COX) catalyze the conversion of arachidonic acid to prostaglandins and thromboxanes during pain and inflammation conditions. These enzymes have also been linked to several other conditions and diseases, and hence, in dentistry, it is crucial to identify the processes that increase the levels of these mediators. This paper aims to describe the significance of COX in dental practice through a narrative review. Methods: Articles relating to COX upregulation published in English and Spanish over the last 51 years in databases such as EBSCO, Google Scholar, Science Direct, PubMed, and Web of Science; were analyzed. Results: A total of 115 articles demonstrating the relationship between COX upregulation and multiple conditions and diseases of importance in prosthodontics, periodontics, oral pathology, orthodontics, and endodontics were included. Conclusions: COX upregulation is related to inflammatory and malignant diseases in oral tissues, such as periodontitis, pulpitis, and oral cancer, nevertheless, its expression is advantageous in other fields of study such as orthodontics. Additionally, is well documented that dental materials provoke an undesired increase in COX expression, which could be a significant factor that directly affects pulpal health.
目的:在疼痛和炎症情况下,环氧化酶(COX)催化花生四烯酸转化为前列腺素和血栓素。这些酶还与其他几种情况和疾病有关,因此,在牙科中,确定增加这些介质水平的过程至关重要。本文旨在通过叙述性综述描述 COX 在牙科实践中的重要性。方法:分析过去 51 年中在 EBSCO、Google Scholar、Science Direct、PubMed 和 Web of Science 等数据库中以英语和西班牙语发表的与 COX 上调有关的文章。结果:共收录了 115 篇文章,这些文章证明了 COX 上调与修复学、牙周病学、口腔病理学、正畸学和牙髓病学中的多种重要情况和疾病之间的关系。结论:COX 上调与牙周炎、牙髓炎和口腔癌等口腔组织的炎症和恶性疾病有关,但其表达在正畸等其他研究领域也有优势。此外,有资料表明,牙科材料会引起 COX 表达的意外增加,这可能是直接影响牙髓健康的一个重要因素。
{"title":"The importance of cyclooxigenase in dentistry","authors":"Sara Delgadillo Barrera, Lilia Jadith Bernal Cepeda, Jaime Eduardo Castellanos Parras","doi":"10.20396/bjos.v23i00.8671181","DOIUrl":"https://doi.org/10.20396/bjos.v23i00.8671181","url":null,"abstract":"Aim: Cyclooxygenase enzymes (COX) catalyze the conversion of arachidonic acid to prostaglandins and thromboxanes during pain and inflammation conditions. These enzymes have also been linked to several other conditions and diseases, and hence, in dentistry, it is crucial to identify the processes that increase the levels of these mediators. This paper aims to describe the significance of COX in dental practice through a narrative review. Methods: Articles relating to COX upregulation published in English and Spanish over the last 51 years in databases such as EBSCO, Google Scholar, Science Direct, PubMed, and Web of Science; were analyzed. Results: A total of 115 articles demonstrating the relationship between COX upregulation and multiple conditions and diseases of importance in prosthodontics, periodontics, oral pathology, orthodontics, and endodontics were included. Conclusions: COX upregulation is related to inflammatory and malignant diseases in oral tissues, such as periodontitis, pulpitis, and oral cancer, nevertheless, its expression is advantageous in other fields of study such as orthodontics. Additionally, is well documented that dental materials provoke an undesired increase in COX expression, which could be a significant factor that directly affects pulpal health.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"66 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140486223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orthognathic surgery in a patient with von Willebrand disease 一名冯-威廉氏病患者的正颌外科手术
Q4 Dentistry Pub Date : 2024-01-29 DOI: 10.20396/bjos.v23i00.8671965
Bhárbara Mariano Barcellos, Andressa Goicochea Moreira, Isabela Toledo Teixeira da Silveira, Eduardo de Freitas Gomes, Cristina Braga Xavier, O. C. Chagas Júnior
Aim: This study aims to report the perioperative management of a patient with von Willebrand disease (vWd) who underwent orthognathic surgery. The report follows the guidelines of the Case Report Guidelines (CARE) and focuses on the steps taken to prevent bleeding during the surgical procedure. Methods: A 39-year-old female patient with skeletal Class III was treated with maxillary advancement and mandibular setback. Despite normal test results for ristocetin cofactor activity, measures were taken to prevent bleeding, including atraumatic surgical techniques, use of antifibrinolytic medication, induced hypotension during anesthesia, and preparation of blood products for transfusion during trans and postoperative periods if needed. In the end, these measures were not required. Results: The patient did not experience any bleeding during the surgical procedure or postoperative period, demonstrating the effectiveness of the measures taken to manage their blood dyscrasia. Two years after the surgery, the patient had satisfactory aesthetic and functional results and no evidence of relapse. Conclusion: Thus, this case report demonstrates that vWd does not prevent largescale oral and maxillofacial surgeries such as orthognathic surgery as long as proper precautions are taken pre-, intraand postoperatively.
目的:本研究旨在报告一名接受正颌外科手术的冯-威廉氏病(von Willebrand disease,vWd)患者的围手术期处理情况。报告遵循《病例报告指南》(CARE)的指导方针,重点介绍在手术过程中为防止出血而采取的措施。方法:一名 39 岁的女性患者,骨骼Ⅲ级,接受了上颌前突和下颌后缩治疗。尽管利斯托西汀辅助因子活性检测结果正常,但还是采取了一些措施来预防出血,包括无创伤手术技巧、使用抗纤维蛋白溶解药物、麻醉期间诱导低血压、准备血制品以便在经皮手术和术后需要时输血。最终,这些措施都是不必要的。手术结果患者在手术过程中和术后均未出现任何出血现象,这表明为控制其血液异常所采取的措施是有效的。术后两年,患者的美观和功能效果令人满意,没有复发的迹象。结论:因此,本病例报告表明,只要在术前、术中和术后采取适当的预防措施,vWd 并不会妨碍大型口腔颌面外科手术,例如正颌外科手术。
{"title":"Orthognathic surgery in a patient with von Willebrand disease","authors":"Bhárbara Mariano Barcellos, Andressa Goicochea Moreira, Isabela Toledo Teixeira da Silveira, Eduardo de Freitas Gomes, Cristina Braga Xavier, O. C. Chagas Júnior","doi":"10.20396/bjos.v23i00.8671965","DOIUrl":"https://doi.org/10.20396/bjos.v23i00.8671965","url":null,"abstract":"Aim: This study aims to report the perioperative management of a patient with von Willebrand disease (vWd) who underwent orthognathic surgery. The report follows the guidelines of the Case Report Guidelines (CARE) and focuses on the steps taken to prevent bleeding during the surgical procedure. Methods: A 39-year-old female patient with skeletal Class III was treated with maxillary advancement and mandibular setback. Despite normal test results for ristocetin cofactor activity, measures were taken to prevent bleeding, including atraumatic surgical techniques, use of antifibrinolytic medication, induced hypotension during anesthesia, and preparation of blood products for transfusion during trans and postoperative periods if needed. In the end, these measures were not required. Results: The patient did not experience any bleeding during the surgical procedure or postoperative period, demonstrating the effectiveness of the measures taken to manage their blood dyscrasia. Two years after the surgery, the patient had satisfactory aesthetic and functional results and no evidence of relapse. Conclusion: Thus, this case report demonstrates that vWd does not prevent largescale oral and maxillofacial surgeries such as orthognathic surgery as long as proper precautions are taken pre-, intraand postoperatively.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"59 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140485806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of aging on the accuracy of marginal adaptation and fracture resistance of CAD/CAM PEEK single crown restoration 老化对 CAD/CAM PEEK 单冠修复体边缘适应性和抗折性准确性的影响
Q4 Dentistry Pub Date : 2024-01-14 DOI: 10.20396/bjos.v23i00.8673158
Afaf A Almabadi
Aim: In recent years, great advances have been made in the use of CAD/CAM to prepare fixed restorations. The marginal and internal fit of these restorations is a principal determinant for their clinical success. In addition, the nature of the oral environment affects the mechanical properties of these restorations. Therefore, this study aimed to investigate the effect of aging process under conditions that simulate the oral environment on the marginal adaptation, and, fracture resistance of crowns fabricated from polyether ether ketone (PEEK) using CAD/CAM methods. Methods: Twenty identical crown restorations were fabricated by using CAD/CAM methods to mill polyether ether ketone (PEEK) material. These crowns were produced by using a software design of an epoxy resin replica of the prepared maxillary first premolar tooth. All PEEK crowns were cemented and randomly divided into two equal groups (A, B). Each group was divided into subgroups (A1, A2 and B1, B2). Group A1 and A2 were used to measure marginal adaptation and fracture resistance, respectively, before aging, while group (B1 and B2) were measured after aging. The cemented crowns were mounted in resin molds to facilitate the sectioning process. The measurements of the marginal gap were performed after sectioning at four points using a stereomicroscope. The fracture resistance of the crowns was investigated using a universal testing machine. A statistical analysis was performed using the GraphPad Prism® software version and unpaired Student’s t-test. Results: The results revealed that aging affected the marginal gap, and the fracture resistance of the PEEK crowns. While aging, negatively affected the conditions under investigation, however the least significant difference of marginal gap was found in the margin region. Conclusions: PEEK-CAD/CAM is considered as a good alternative prosthodontic material for fixed prostheses. The CAD/CAM technique used to make PEEK crown restorations in our study offers the advantages of high marginal accuracy and fracture resistance for long-term performance in the oral environment.
目的:近年来,在使用计算机辅助设计/计算机辅助制造(CAD/CAM)技术制作固定修复体方面取得了巨大进步。这些修复体的边缘和内部密合性是其临床成功的主要决定因素。此外,口腔环境的性质也会影响这些修复体的机械性能。因此,本研究旨在研究在模拟口腔环境的条件下,老化过程对使用 CAD/CAM 方法制作的聚醚醚酮(PEEK)牙冠的边缘适应性和抗折性的影响。方法:使用 CAD/CAM 方法研磨聚醚醚酮(PEEK)材料,制作 20 个相同的牙冠修复体。这些牙冠是通过软件设计制作的上颌第一前磨牙环氧树脂复制品。所有的 PEEK 牙冠均已粘接,并随机分为两个相等的组(A、B)。每组又分为子组(A1、A2 和 B1、B2)。A1 和 A2 组分别用于测量老化前的边缘适应性和抗折性,而 B1 和 B2 组则在老化后进行测量。粘结的牙冠安装在树脂模具中,以方便切片过程。切片后使用体视显微镜测量四个点的边缘间隙。使用万能试验机对牙冠的抗折性进行了研究。使用 GraphPad Prism® 软件版本和非配对学生 t 检验进行统计分析。结果结果显示,老化会影响 PEEK 牙冠的边缘间隙和抗折断性。虽然老化对调查条件有负面影响,但边缘区域的边缘间隙差异最小。结论:PEEK-CAD/CAM被认为是固定修复体的良好替代修复材料。在我们的研究中,使用 CAD/CAM 技术制作 PEEK 牙冠修复体具有边缘精确度高和抗折性好的优点,可在口腔环境中长期使用。
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Brazilian Journal of Oral Sciences
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