{"title":"The role of signal pathways and receptors in various layers of mucosa in overactive bladder","authors":"Li Wen, Chen Yuelai","doi":"10.12307/2021.126","DOIUrl":"https://doi.org/10.12307/2021.126","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"4230"},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45738444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HuiLi HuiLi, Li Danyang, Nie Qiu, Niakan Lili, Chen Yiyi
{"title":"Transcranial direct current stimulations at bilateral brain motor areas elevate maximum output power of both lower limbs","authors":"HuiLi HuiLi, Li Danyang, Nie Qiu, Niakan Lili, Chen Yiyi","doi":"10.12307/2021.106","DOIUrl":"https://doi.org/10.12307/2021.106","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"4180"},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46266367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fang Xiaoqian, C. Feng, Liang Xiongqin, G. Sen, Yang Xinqiang
摘要 背景:黄韧带的肥厚纤维化被认为是造成腰椎椎管狭窄症的主要原因。近年来,多有研究报道黄韧带肥厚纤维化与多种生长因子、微小 RNA及关键信号通路相关。 目的:通过细读国内外相关文献,以期为黄韧带组织肥厚纤维化分子水平及信号通路的研究进展做一系统综述。 方法:采用以下检索词:腰椎椎管狭窄症;黄韧带肥厚;黄韧带增生;黄韧带纤维化;细胞因子;蛋白;信号通路;微小RNA;lumbar spinal stenosis;hypertrophy of ligamentum flavum;ligamentum flavum hyperplasia;fibrosis of ligamentum flavum;cell factor;protein; signal path;microRNA,检索知网数据库、维普数据库、万方数据平台、PubMed数据库、Biosos Preview数据库及Web Of Science数据库, 并手工检索,收集有关研究黄韧带组织肥厚纤维化的基础实验,检索时限设为建库至2020-06-30。严格按照纳入标准对所检索文献进行 筛选,共纳入15篇有关的基础实验文献进行综述探讨。 结果与结论:现有的实验研究,可以发现在黄韧带组织肥厚纤维化的过程中,存在有多种生长因子及miRNA参与表达并表现出活性增加的 现象,同时发现有关键信号通路参与调控黄韧带组织的纤维化过程。因此,有理由推测黄韧带增生纤维化是多种生物学过程协同参与、 多维作用的共同结果;但影响的纤维化程度在目前尚未确定,未来仍需进一步行基础研究以探索验证。 关键词:黄韧带;肥厚;纤维化;分子水平;基础实验;生长因子;微小RNA;信号通路 缩略语:基质金属蛋白酶组织抑制剂:tissue inhibitor of metalloproteinases,TIMPs;丝裂原活化蛋白激酶:mitogen activated protein kinase,MAPK
摘要 背景:黄韧带的肥厚纤维化被认为是造成腰椎椎管狭窄症的主要原因。近年来,多有研究报道黄韧带肥厚纤维化与多种生长因子、微小 RNA及关键信号通路相关。 目的:通过细读国内外相关文献,以期为黄韧带组织肥厚纤维化分子水平及信号通路的研究进展做一系统综述。 方法:采用以下检索词:腰椎椎管狭窄症;黄韧带肥厚;黄韧带增生;黄韧带纤维化;细胞因子;蛋白;信号通路;微小RNA;lumbar spinal stenosis;hypertrophy of ligamentum flavum;ligamentum flavum hyperplasia;fibrosis of ligamentum flavum;cell factor;protein; signal path;microRNA,检索知网数据库、维普数据库、万方数据平台、PubMed数据库、Biosos Preview数据库及Web Of Science数据库, 并手工检索,收集有关研究黄韧带组织肥厚纤维化的基础实验,检索时限设为建库至2020-06-30。严格按照纳入标准对所检索文献进行 筛选,共纳入15篇有关的基础实验文献进行综述探讨。 结果与结论:现有的实验研究,可以发现在黄韧带组织肥厚纤维化的过程中,存在有多种生长因子及miRNA参与表达并表现出活性增加的 现象,同时发现有关键信号通路参与调控黄韧带组织的纤维化过程。因此,有理由推测黄韧带增生纤维化是多种生物学过程协同参与、 多维作用的共同结果;但影响的纤维化程度在目前尚未确定,未来仍需进一步行基础研究以探索验证。 关键词:黄韧带;肥厚;纤维化;分子水平;基础实验;生长因子;微小RNA;信号通路 缩略语:基质金属蛋白酶组织抑制剂:tissue inhibitor of metalloproteinases,TIMPs;丝裂原活化蛋白激酶:mitogen activated protein kinase,MAPK
{"title":"Hypertrophic fibrosis of the ligamentum flavum: signaling pathways and molecular level characteristics","authors":"Fang Xiaoqian, C. Feng, Liang Xiongqin, G. Sen, Yang Xinqiang","doi":"10.12307/2021.128","DOIUrl":"https://doi.org/10.12307/2021.128","url":null,"abstract":"摘要 背景:黄韧带的肥厚纤维化被认为是造成腰椎椎管狭窄症的主要原因。近年来,多有研究报道黄韧带肥厚纤维化与多种生长因子、微小 RNA及关键信号通路相关。 目的:通过细读国内外相关文献,以期为黄韧带组织肥厚纤维化分子水平及信号通路的研究进展做一系统综述。 方法:采用以下检索词:腰椎椎管狭窄症;黄韧带肥厚;黄韧带增生;黄韧带纤维化;细胞因子;蛋白;信号通路;微小RNA;lumbar spinal stenosis;hypertrophy of ligamentum flavum;ligamentum flavum hyperplasia;fibrosis of ligamentum flavum;cell factor;protein; signal path;microRNA,检索知网数据库、维普数据库、万方数据平台、PubMed数据库、Biosos Preview数据库及Web Of Science数据库, 并手工检索,收集有关研究黄韧带组织肥厚纤维化的基础实验,检索时限设为建库至2020-06-30。严格按照纳入标准对所检索文献进行 筛选,共纳入15篇有关的基础实验文献进行综述探讨。 结果与结论:现有的实验研究,可以发现在黄韧带组织肥厚纤维化的过程中,存在有多种生长因子及miRNA参与表达并表现出活性增加的 现象,同时发现有关键信号通路参与调控黄韧带组织的纤维化过程。因此,有理由推测黄韧带增生纤维化是多种生物学过程协同参与、 多维作用的共同结果;但影响的纤维化程度在目前尚未确定,未来仍需进一步行基础研究以探索验证。 关键词:黄韧带;肥厚;纤维化;分子水平;基础实验;生长因子;微小RNA;信号通路 缩略语:基质金属蛋白酶组织抑制剂:tissue inhibitor of metalloproteinases,TIMPs;丝裂原活化蛋白激酶:mitogen activated protein kinase,MAPK","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"4243"},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46869400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhang Lishu, Li Anqi, He Xiaoning, Jin Yan, L. Bei, Jin Fang
{"title":"Alpl gene affects the therapeutic effect of bone marrow mesenchymal stem cells on ulcerative colitis","authors":"Zhang Lishu, Li Anqi, He Xiaoning, Jin Yan, L. Bei, Jin Fang","doi":"10.12307/2021.006","DOIUrl":"https://doi.org/10.12307/2021.006","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"3970"},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42503950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhang Chunxi, L. Xiang, Z. Yuxiang, Liu Zhen, Yang Yuquan, J. Hao
{"title":"Fate decision of mesenchymal stem cells in bone microenvironment","authors":"Zhang Chunxi, L. Xiang, Z. Yuxiang, Liu Zhen, Yang Yuquan, J. Hao","doi":"10.12307/2021.018","DOIUrl":"https://doi.org/10.12307/2021.018","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"4045"},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46018127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Dan, Xu Guanglan, Z. Mei, Li-li Jiao, Lin Guosheng, Wang Guangyao, Lingling Hao, Zheng Manli, Li Yuanling
{"title":"Significance and possibility of stem cells and multiple cell derived exosomes in the treatment of chronic respiratory diseases","authors":"Y. Dan, Xu Guanglan, Z. Mei, Li-li Jiao, Lin Guosheng, Wang Guangyao, Lingling Hao, Zheng Manli, Li Yuanling","doi":"10.12307/2021.019","DOIUrl":"https://doi.org/10.12307/2021.019","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"4053"},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42781518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Jinyu, Ding Yiwei, Lu Zheng-Cao, Gao Tianjun, Cui Hong-Peng, L. Wen, Du Wei, Ding Yu
{"title":"Finite element biomechanical study of full endoscopic fenestration decompression for cervical spondylotic myelopathy","authors":"L. Jinyu, Ding Yiwei, Lu Zheng-Cao, Gao Tianjun, Cui Hong-Peng, L. Wen, Du Wei, Ding Yu","doi":"10.12307/2021.091","DOIUrl":"https://doi.org/10.12307/2021.091","url":null,"abstract":"","PeriodicalId":35055,"journal":{"name":"中国组织工程研究","volume":"25 1","pages":"3850"},"PeriodicalIF":0.0,"publicationDate":"2021-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42177014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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