Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.19ee1aee
Tumalano Sekoto, G. V. Rensburg, Lillian Okui
{"title":"Assessment of knowledge and attitudes towards health research among nurses working in public health facilities in Botswana","authors":"Tumalano Sekoto, G. V. Rensburg, Lillian Okui","doi":"10.21428/3d48c34a.19ee1aee","DOIUrl":"https://doi.org/10.21428/3d48c34a.19ee1aee","url":null,"abstract":"","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115414179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.86f5b001
O. Okonkwo, Jack Lee
This study examined the accessibility of mobile point of care ultrasound among doctors in Nigeria. The objectives of the study were to determine the awareness and availability of mobile point of care ultrasound devices among doctors in clinical practice in Nigeria. This was a descriptive cross-sectional study of which both quantitative and qualitative data collection methods were applied. Data was obtained using a self-administered questionnaire. Data was collected from 396 doctors engaged in active clinical practice across Nigeria. Findings from the study revealed that, whereas 92.6% of these doctors require ultrasound services in their practice, only 58% have direct or indirect access to ultrasound services in their facilities. For 23.1% of the doctors, their patients are sent away to other recommended facilities to access ultrasound services, while 16.9%, do not know where their patients source their ultrasound services. The study further revealed that 55% of the doctors are unaware of the existence of any form of mobile point of care wireless ultrasound devices. However, an overwhelming 93.1% of doctors are convinced that using the device in their practice could enable them improve on the clinical assessment of their patients. Whereas 68.3% of doctors are willing to procure and use the device where available, 31.7% are concerned about the affordability of the mobile device. It is evident that mobile wireless ultrasound device is an innovative technology that is sure to significantly improve clinical diagnosis and case detection, enhance service delivery and overall patients outcome especially for those in resource poor environments. This device has the potential to practically eliminate barriers to accessibility of ultrasound guided diagnosis for prompt case detection for population in remote communities. There is therefore the need for increased investment in making this technology widely available to clinicians wherever they are needed. Further research would be required to ascertain the general ultrasound knowledge of these clinicians and routine capacity building provided to continually strengthen their ultrasound guided diagnostics skills.
{"title":"Assessment of the accessibility of point of care ultrasound services among primary care providers in Nigeria.","authors":"O. Okonkwo, Jack Lee","doi":"10.21428/3d48c34a.86f5b001","DOIUrl":"https://doi.org/10.21428/3d48c34a.86f5b001","url":null,"abstract":"This study examined the accessibility of mobile point of care ultrasound among doctors in Nigeria. The objectives of the study were to determine the awareness and availability of mobile point of care ultrasound devices among doctors in clinical practice in Nigeria. This was a descriptive cross-sectional study of which both quantitative and qualitative data collection methods were applied. Data was obtained using a self-administered questionnaire. Data was collected from 396 doctors engaged in active clinical practice across Nigeria. Findings from the study revealed that, whereas 92.6% of these doctors require ultrasound services in their practice, only 58% have direct or indirect access to ultrasound services in their facilities. For 23.1% of the doctors, their patients are sent away to other recommended facilities to access ultrasound services, while 16.9%, do not know where their patients source their ultrasound services. The study further revealed that 55% of the doctors are unaware of the existence of any form of mobile point of care wireless ultrasound devices. However, an overwhelming 93.1% of doctors are convinced that using the device in their practice could enable them improve on the clinical assessment of their patients. Whereas 68.3% of doctors are willing to procure and use the device where available, 31.7% are concerned about the affordability of the mobile device. It is evident that mobile wireless ultrasound device is an innovative technology that is sure to significantly improve clinical diagnosis and case detection, enhance service delivery and overall patients outcome especially for those in resource poor environments. This device has the potential to practically eliminate barriers to accessibility of ultrasound guided diagnosis for prompt case detection for population in remote communities. There is therefore the need for increased investment in making this technology widely available to clinicians wherever they are needed. Further research would be required to ascertain the general ultrasound knowledge of these clinicians and routine capacity building provided to continually strengthen their ultrasound guided diagnostics skills.","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123689126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.be40c208
K. Govindarajan, Knj Prakash Raju, Jagdish Sadasivam
{"title":"Pediatric Trauma: where do we stand?","authors":"K. Govindarajan, Knj Prakash Raju, Jagdish Sadasivam","doi":"10.21428/3d48c34a.be40c208","DOIUrl":"https://doi.org/10.21428/3d48c34a.be40c208","url":null,"abstract":"","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123885724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.74e22191
E. Abe, B. Adeyemi, A. Adisa, B. Kolude, M. Arowojolu, C. Hawkins
{"title":"HIV-Oral Lesions, Secretory Immunoglobulin A (SIGA) and Salivary Cytokine Profile among Adults Newly Diagnosed with HIV/AIDS","authors":"E. Abe, B. Adeyemi, A. Adisa, B. Kolude, M. Arowojolu, C. Hawkins","doi":"10.21428/3d48c34a.74e22191","DOIUrl":"https://doi.org/10.21428/3d48c34a.74e22191","url":null,"abstract":"","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121519874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.119d9c4e
Yaocihuatl Castañeda Borrayo, S. L. Cortés, Leslie Guadalupe Rivera Rodríguez
Yaocihuatl Castañeda Borrayo1 Silvia Graciela León Cortés2 Leslie Guadalupe Rivera Rodríguez2 1Instituto Mexicano del Seguro Social, Unidad de Investigación Epidemiológica y en Servicios de Salud, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social (IMSS), Órganos de Operación Administrativa Desconcentrada., Mexico, 2University of Guadalajara, University Center for Health Sciences, Department of Public Health, Doctorate in Occupational Health Sciences., Mexico
{"title":"Diabetes mellitus as a cause of disability in Mexico from 1998 to 2020.","authors":"Yaocihuatl Castañeda Borrayo, S. L. Cortés, Leslie Guadalupe Rivera Rodríguez","doi":"10.21428/3d48c34a.119d9c4e","DOIUrl":"https://doi.org/10.21428/3d48c34a.119d9c4e","url":null,"abstract":"Yaocihuatl Castañeda Borrayo1 Silvia Graciela León Cortés2 Leslie Guadalupe Rivera Rodríguez2 1Instituto Mexicano del Seguro Social, Unidad de Investigación Epidemiológica y en Servicios de Salud, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social (IMSS), Órganos de Operación Administrativa Desconcentrada., Mexico, 2University of Guadalajara, University Center for Health Sciences, Department of Public Health, Doctorate in Occupational Health Sciences., Mexico","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121605605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.7b5e379a
Voke Toye, Emmanuel Afolayemi, Dorcas Akinuli, Alfred Akinlalu, Ijeoma Asilebo
Viral DNA quantification of Hepatitis B Virus (HBV) is crucial in treating and managing patients with chronic HBV disease. Although serological testing has contributed immensely to the disease diagnosis, molecular methods such as the quantitative Polymerase Chain Reaction (qPCR) are vital in viral load determination. This quantification technique is important for physicians to monitor the progress of antiviral therapy and determine future therapeutic options. In this study, we evaluated the detection efficiency of commercially available kits used in qPCR detection for the HBV viral load quantification. Serum cell-free circulating DNA of 37 patients that have been serologically confirmed positive for HBV and 13 healthy controls were extracted, and qPCR viral load determination was carried out. The results showed that only 13.51 % of the total HBV-positive samples were sufficiently high to be detected with viral load ranges from 0.87 – 1012 IU/mL. The high number of undetected cases 86.49 % may be attributed to the qPCR kit sensitivity as well as variations in the region of detection of viral genome found in the Nigerian population since these kits were designed for a different populace. This necessitates further studies that will validate the underlying mechanisms for the detection of the virus and see the need for indigenous detection kits to address the disease burden of HBV in Nigeria.
{"title":"Determination of HBV DNA viral load in Serum positive Hepatitis B patients using Quantitative Real Time PCR (qPCR)","authors":"Voke Toye, Emmanuel Afolayemi, Dorcas Akinuli, Alfred Akinlalu, Ijeoma Asilebo","doi":"10.21428/3d48c34a.7b5e379a","DOIUrl":"https://doi.org/10.21428/3d48c34a.7b5e379a","url":null,"abstract":"Viral DNA quantification of Hepatitis B Virus (HBV) is crucial in treating and managing patients with chronic HBV disease. Although serological testing has contributed immensely to the disease diagnosis, molecular methods such as the quantitative Polymerase Chain Reaction (qPCR) are vital in viral load determination. This quantification technique is important for physicians to monitor the progress of antiviral therapy and determine future therapeutic options. In this study, we evaluated the detection efficiency of commercially available kits used in qPCR detection for the HBV viral load quantification. Serum cell-free circulating DNA of 37 patients that have been serologically confirmed positive for HBV and 13 healthy controls were extracted, and qPCR viral load determination was carried out. The results showed that only 13.51 % of the total HBV-positive samples were sufficiently high to be detected with viral load ranges from 0.87 – 1012 IU/mL. The high number of undetected cases 86.49 % may be attributed to the qPCR kit sensitivity as well as variations in the region of detection of viral genome found in the Nigerian population since these kits were designed for a different populace. This necessitates further studies that will validate the underlying mechanisms for the detection of the virus and see the need for indigenous detection kits to address the disease burden of HBV in Nigeria.","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122113407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.d27f28ed
Ruth M. Ogboye, J. Soyinka, O. Bolaji, A. Adegbola
As per current treatment guidelines, artemether-lumefantrine, and efavirenz (EFV)-based antiretroviral therapy are recommended drugs for falciparum malaria and HIV infections, respectively. A liquid chromatography-ultraviolet detection (LC-UV) method for simultaneous quantification of lumefantrine and EFV was developed and validated for efficacy and pharmacokinetic clinical studies. Lumefantrine and EFV were separated using a 100 x 4.6 mm x 3 µm Fortis C 18 chromatographic column, and a multistep gradient mobile phase. Calibration was obtained with a series of standard solutions containing known concentrations of the chemical reference of both analytes prepared concomitantly in drug-free plasma. The assay was validated within the calibration ranges of 78.125 to 20000 ng/mL for lumefantrine and 187.15 to 24000 ng/mL for EFV. Stability assessment was carried out with or without heating the quality sample to 58°C for 45 min. The method was employed to measure the plasma concentrations of lumefantrine and EFV in a study conducted among malaria-HIV co-infected patients. Lumefantrine and EFV were well separated from each other and from the biological matrix. The method demonstrated a good recovery of 72.64% for lumefantrine and 117.17% for EFV. The intra-and inter-day accuracy presented as 95.36-105.14% for lumefantrine and 104.11-115% for EFV and precision ranged from 1.15 to 6.45% for lumefantrine and 0.43 to 13.12 for EFV, were within ±15% at the three quality control levels. The analytes from both quality control lots and samples collected from HIV-malaria co-infected individuals were found to be stable post-deactivation of infectious virus by heating to 58 °C for 45 min. The assay is accurate, precise and shown to simultaneously measure the lumefantrine and EFV in human
{"title":"A simple high-performance liquid chromatographic assay for lumefantrine in plasma in the presence of efavirenz-based antiretroviral therapy","authors":"Ruth M. Ogboye, J. Soyinka, O. Bolaji, A. Adegbola","doi":"10.21428/3d48c34a.d27f28ed","DOIUrl":"https://doi.org/10.21428/3d48c34a.d27f28ed","url":null,"abstract":"As per current treatment guidelines, artemether-lumefantrine, and efavirenz (EFV)-based antiretroviral therapy are recommended drugs for falciparum malaria and HIV infections, respectively. A liquid chromatography-ultraviolet detection (LC-UV) method for simultaneous quantification of lumefantrine and EFV was developed and validated for efficacy and pharmacokinetic clinical studies. Lumefantrine and EFV were separated using a 100 x 4.6 mm x 3 µm Fortis C 18 chromatographic column, and a multistep gradient mobile phase. Calibration was obtained with a series of standard solutions containing known concentrations of the chemical reference of both analytes prepared concomitantly in drug-free plasma. The assay was validated within the calibration ranges of 78.125 to 20000 ng/mL for lumefantrine and 187.15 to 24000 ng/mL for EFV. Stability assessment was carried out with or without heating the quality sample to 58°C for 45 min. The method was employed to measure the plasma concentrations of lumefantrine and EFV in a study conducted among malaria-HIV co-infected patients. Lumefantrine and EFV were well separated from each other and from the biological matrix. The method demonstrated a good recovery of 72.64% for lumefantrine and 117.17% for EFV. The intra-and inter-day accuracy presented as 95.36-105.14% for lumefantrine and 104.11-115% for EFV and precision ranged from 1.15 to 6.45% for lumefantrine and 0.43 to 13.12 for EFV, were within ±15% at the three quality control levels. The analytes from both quality control lots and samples collected from HIV-malaria co-infected individuals were found to be stable post-deactivation of infectious virus by heating to 58 °C for 45 min. The assay is accurate, precise and shown to simultaneously measure the lumefantrine and EFV in human","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"616 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120932829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.9fb17916
N. North, Andrea Amos, Busisiwe Jama, M. Coetzee
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{"title":"Facilitating data-driven evidence-based practice change: the Best Practice Project","authors":"N. North, Andrea Amos, Busisiwe Jama, M. Coetzee","doi":"10.21428/3d48c34a.9fb17916","DOIUrl":"https://doi.org/10.21428/3d48c34a.9fb17916","url":null,"abstract":";","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123851844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.180cc7cb
Mosamat Umma Kulsum, Ishtiaq Hossain Ornab
{"title":"Engaging the community and building public trust in health research.","authors":"Mosamat Umma Kulsum, Ishtiaq Hossain Ornab","doi":"10.21428/3d48c34a.180cc7cb","DOIUrl":"https://doi.org/10.21428/3d48c34a.180cc7cb","url":null,"abstract":"","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130543692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.21428/3d48c34a.3e95aec1
Jane Kahindi, Grace Mwango, Alun Davies, D. Kamuya
{"title":"Developing and evaluating a video to engage the lay public about biobanks and biobanking","authors":"Jane Kahindi, Grace Mwango, Alun Davies, D. Kamuya","doi":"10.21428/3d48c34a.3e95aec1","DOIUrl":"https://doi.org/10.21428/3d48c34a.3e95aec1","url":null,"abstract":"","PeriodicalId":353726,"journal":{"name":"The Global Health Network Conference Proceedings 2022","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128404128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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