Abstract In the modern medical literature, alopecia totalis has been reported as early as the 1940s. Childhood alopecia totalis is a heterogeneous disorder that occur in syndromic and non-syndromic forms and can have autoimmune, nutritional and genetic bases. Non-syndromic childhood alopecia totalis is generally has autoimmune bases. During the 1970s, authors reported the treatment of alopecia totalis with DNCB which is 1-chloro, 2, 4-dinitrobenzene and High-dose glucocorticoid. Early during the 1980s, oral photochemotherapy was used in the treatment of alopecia totalis without the occurrence of side effects. The aim of this paper is to present a case of childhood non-syndromic alopecia totalis and to review of the available evidence-based therapies.
{"title":"Childhood Alopecia Totalis: A Case and A Concise Review of The\u0000Available Evidence-Based Therapies.","authors":"Aamir Jalal Al-Mosawi","doi":"10.46940/sjdsd.01.1001","DOIUrl":"https://doi.org/10.46940/sjdsd.01.1001","url":null,"abstract":"Abstract \u0000In the modern medical literature, alopecia totalis has been reported as early as the 1940s. Childhood alopecia totalis is a heterogeneous disorder that occur in syndromic and non-syndromic forms and can have autoimmune, nutritional and genetic bases. Non-syndromic childhood alopecia totalis is generally has autoimmune bases. During the 1970s, authors reported the treatment of alopecia totalis with DNCB which is 1-chloro, 2, 4-dinitrobenzene and High-dose glucocorticoid. Early during the 1980s, oral photochemotherapy was used in the treatment of alopecia totalis without the occurrence of side effects. The aim of this paper is to present a case of childhood non-syndromic alopecia totalis and to review of the available evidence-based therapies.","PeriodicalId":355163,"journal":{"name":"SunKrist Journal of Dermatology and Skin Diseases","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129737477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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