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Assessing frailty in urogynecology patients: a comparative analysis of the Edmonton frail scale and pelvic floor symptom severity 评估泌尿妇科病人的虚弱:埃德蒙顿虚弱量表和骨盆底症状严重程度的比较分析
Q4 Medicine Pub Date : 2023-10-30 DOI: 10.4081/uij.2023.309
Stephanie W. Zuo, Jaden R. Kohn, Chi Chiung Grace Chen, Laura Tellechea, Harley Roberts, Ilir Agalliu, Ava Leegant, Nitya Abraham, Melissa Laudano
This study aimed to measure frailty using the Edmonton frail scale (EFS) and examine whether frailty is associated with presenting complaints or worse pelvic floor symptom severity in older urogynecology outpatients. We conducted a cross-sectional study of new urogynecology patients aged 50 and older at 2 urban academic centers between November 2018 and January 2020. Pelvic floor symptom severity was assessed using surveys [overactive bladder validated 8-question screener (OAB-V8), pelvic floor distress inventory, and 6-item female sexual function index]. Multivariable linear and logistic regression analyses were performed to compare chief complaint and questionnaire scores by EFS score, frailty status, and EFS component. A total of 138 women were recruited, with a mean age of 65 years (standard deviation 9.3). 11.6% met the criteria for frailty. Frail women had 6.2 greater adjusted odds of endorsing urinary incontinence symptoms as their presenting complaint, and women with higher EFS scores had worse OAB-V8 scores (adjusted ß=0.04, p=0.03). Depression/sadness were associated with worse urinary and prolapse symptoms. Frailty is common in older urogynecology outpatients, especially those presenting with urinary incontinence. Individual components of the EFS associated with symptomatic pelvic floor dysfunction included depressed mood, lack of reliable help, and incontinence.
本研究旨在使用埃德蒙顿虚弱量表(EFS)测量虚弱,并检查老年泌尿妇科门诊患者的虚弱是否与主诉或更严重的盆底症状严重程度有关。我们在2018年11月至2020年1月期间在2个城市学术中心对50岁及以上的泌尿妇科新患者进行了横断面研究。盆底症状严重程度通过调查[膀胱过度活动验证8题筛查(OAB-V8),盆底窘迫量表和6项女性性功能指数]进行评估。采用多变量线性和逻辑回归分析比较主诉和问卷调查的EFS评分、虚弱状态和EFS成分。共招募了138名女性,平均年龄65岁(标准差9.3)。11.6%符合虚弱标准。体弱多病的女性以尿失禁症状为主诉的调整后几率高出6.2倍,EFS评分较高的女性OAB-V8评分较差(调整后ß=0.04, p=0.03)。抑郁/悲伤与更严重的尿和脱垂症状相关。虚弱是常见的老年泌尿妇科门诊患者,特别是那些表现为尿失禁。与症状性盆底功能障碍相关的EFS的个别成分包括情绪低落、缺乏可靠的帮助和尿失禁。
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引用次数: 0
Prevalent practices and changing trends in the management of vesicovaginal fistula: a cross-sectional study from a nationwide questionnaire-based survey of urologists from a developing country 膀胱阴道瘘管理的流行做法和变化趋势:一项来自发展中国家泌尿科医生的全国性问卷调查的横断面研究
Q4 Medicine Pub Date : 2023-10-26 DOI: 10.4081/uij.2023.313
Anupam Choudhary, Anshuman Singh, Suyog Shetty, Surag K.R., Manjunath Irappa Wali, Arun Chawla, Padmaraj Hegde, Bommireddy V. Reddy, Goli Venkata Sai Abhishek
Vesicovaginal fistula (VVF) management is primarily backed by evidence from retrospective studies and expert opinions and therefore lacks standardization. Newer generations of surgeons are more proactive toward changing clinical practices in domains lacking good-quality evidence. This survey-based cross-sectional study aims to elicit consensus on management practices regarding various domains of VVF management and look for any changes in clinical practice trends. A nationwide survey of urologists was conducted, and responses were grouped into 3 categories (overall response, response from young urologists, and response from experienced urologists) and compared. Based on the level of overall consensus, the responses were categorized as highly preferred, preferred, and somewhat preferred. Consensus was noted in conservative and endoscopic management of VVF, timing of VVF repair, definition of simple/complex VVF, approach for surgical repair for trigonal and supratrigonal VVF, use of interposition tissue for repair, and patient positioning in the postoperative period. A lack of consensus was noted in other domains. Changing trends in clinical practices were noted in attempts at conservative and endoscopic management, investigations considered mandatory for evaluation, surgical approach for complex VVF with bladder neck involvement and radiation-induced fistulas, the use of interposition grafts during surgical repair, the use of cystograms during follow-up, and the definition of a successful repair. There is uniformity in practices regarding many domains of VVF management. Those areas, where discordance in opinions is noted, require further research to bring standardization into practice. Regarding certain aspects of VVF management, there appears to be a change in trends among the younger generation of urologists.
膀胱阴道瘘(VVF)的管理主要由回顾性研究和专家意见的证据支持,因此缺乏标准化。新一代的外科医生在缺乏高质量证据的领域更积极主动地改变临床实践。这项基于调查的横断面研究旨在就VVF管理的各个领域的管理实践达成共识,并寻找临床实践趋势的任何变化。我们在全国范围内对泌尿科医生进行了调查,并将反馈分为3类(总体反馈、年轻泌尿科医生反馈和经验丰富泌尿科医生反馈)进行比较。基于总体共识的水平,回答被分类为高度首选,首选和有些首选。在VVF的保守和内镜治疗、VVF修复的时机、简单/复杂VVF的定义、三角和表上VVF的手术修复方法、修复间置组织的使用以及术后患者的体位等方面达成了共识。注意到在其他领域缺乏协商一致意见。临床实践的变化趋势被注意到在保守和内窥镜治疗的尝试、评估的强制性检查、累及膀胱颈部和辐射引起的瘘管的复杂VVF的手术入路、手术修复时插入移植物的使用、随访时膀胱造影的使用以及成功修复的定义。关于VVF管理的许多领域的实践是一致的。注意到意见不一致的那些领域需要进一步研究,以便实行标准化。关于VVF管理的某些方面,在年轻一代的泌尿科医生中似乎有变化的趋势。
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引用次数: 0
Residents’ experience and training in obstetric anal sphincter injury repair in the United States 美国住院医师产科肛门括约肌损伤修复的经验与培训
Q4 Medicine Pub Date : 2023-06-05 DOI: 10.4081/uij.2023.299
S. Narayanamoorthy, K. Balhotra, M. Silver, Rodney McLaren Jr., E. Mckay
With the reduction in obstetric anal sphincter injuries (OASIS) cases, it is unknown if learning and exposure to their repair is compromised during obstetrics and gynecology (OBGYN) residency in the United States (US). The aim of this study was to evaluate the exposure and confidence level of the US OBGYN residents to OASIS repair. Residents’ education on OASIS repair was also assessed. This was a cross sectional online survey that collected residents’ demographics, characteristics of residency program, the number of deliveries and OASIS repairs performed, the site and technique of OASIS repair, post-repair care provided, residents’ confidence level in OASIS repair and their education on the repair. Descriptive analyses, Fisher’s Exact tests, Ordinal regression models and Spearman’s correlation were performed. Response from 160 residents (11% response rate) was obtained. Confidence was higher with increasing level of training (OR = 3.442, 95% CI, 2.473-4.791, p<0.004), a greater number of deliveries (OR=2.672, 95% CI, 1.511-4.723, p<0.001), third-degree repairs (OR=5.522, 95%CI, 3.67-8.308, p<0.001) and fourth-degree repairs (OR=4.364, 95% CI, 2.785-6.837, p<0.001) performed. Exposure to lecture or/and simulation improved confidence than no exposure to either (OR= 0.225, 95% CI, 0.092-0.545, p<0.001). Residents’ confidence level increased with a greater number of simulations attended (r=0.368, p< 0.001). Lectures and simulations enhance residents’ knowledge and skills in OASIS repair. Surgical skill curriculum is essential to maintain good quality training, prompt recognition, and meticulous perineal repair among OBGYN physicians despite the declining OASIS cases.
随着产科肛门括约肌损伤(OASIS)病例的减少,尚不清楚在美国妇产科(OBGYN)住院医师期间,学习和接触肛门括约肌修复是否受到损害。本研究的目的是评估美国妇产科住院医师对OASIS修复的暴露程度和置信度。居民对绿洲修复的教育程度也进行了评估。这是一项横断面在线调查,收集了居民的人口统计数据、居住计划的特征、交付和OASIS维修的数量、OASIS维修的地点和技术、提供的修复后护理、居民对OASIS维修的信心水平以及他们对维修的了解。采用描述性分析、Fisher精确检验、序数回归模型和Spearman相关分析。获得了160名居民的回复(11%的回复率)。随着培训水平的提高(OR= 3.442, 95%CI, 2.473-4.791, p<0.004),更多的分娩(OR=2.672, 95%CI, 1.511-4.723, p<0.001),三级修复(OR=5.522, 95%CI, 3.67-8.308, p<0.001)和四级修复(OR=4.364, 95%CI, 2.785-6.837, p<0.001),置信度更高。接触讲座或/和模拟比不接触任何一种都提高了信心(or = 0.225, 95% CI, 0.092-0.545, p<0.001)。居民的信心水平随着模拟次数的增加而增加(r=0.368, p< 0.001)。讲座及模拟活动提高居民对绿洲维修的知识和技能。尽管OASIS病例不断减少,但外科技能课程对于保持高质量的培训,及时识别和细致的会阴修复在妇产科医生中是必不可少的。
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引用次数: 0
Impact of vaginal submucosal platelet-rich plasma combined with non-cross-linked hyaluronic acid injections on dyspareunia and sexual satisfaction in a Hodgkin lymphoma cancer survivor: a case report 阴道粘膜下富血小板血浆联合非交联透明质酸注射对霍奇金淋巴瘤幸存者性交困难和性满意度的影响:1例报告
Q4 Medicine Pub Date : 2023-05-30 DOI: 10.4081/uij.2023.306
Salma Samir Omar, Khaled F. Elmulla, Noran Abo Khadr, Ahmed Ashour Badawy, Eman Nabih Ramadan, Ahmed Hassouna, Lamia Heikal, Waleed Arafat
Vaginal atrophy is a commonly encountered problem among young cancer survivors. Patients suffer from vaginal dryness, irritation, and dyspareunia secondary to oestrogen deficiency. Oestrogenbased hormone replacement therapy is effective, but unfortunately health concerns or contraindications in cancer survivors frequently limit its use. A 35-year-old female patient with dyspareunia that markedly affected her sexual relationship was referred to the gynaecology clinic. Treatment using topical oestrogen cream and sexual counselling were not successful. We treated her using two submucosal injections of PRP-non-cross-linked hyaluronic acid injections into the vestibule and lower third of the anterior vaginal wall mucosa, spaced a month apart. The patient reported marked reduction of dyspareunia and demonstrated an improvement of FSFI total score 1 month after the second injection. Both the patient and her husband showed an improvement of the index of sexual satisfaction score one month after the second injection compared to their pretreatment scores. Examination of the vaginal mucosa showed improvement of thickness and integrity of the mucosa and increased lubrication. PRP-non-cross-linked hyaluronic acid submucosal injections can be effective for cancer therapy-related vaginal atrophy, coitus-related pain, and sexual satisfaction.
阴道萎缩是年轻癌症幸存者中常见的问题。由于雌激素缺乏,患者会出现阴道干燥、刺激和性交困难。基于雌激素的激素替代疗法是有效的,但不幸的是,癌症幸存者的健康问题或禁忌症经常限制其使用。一位35岁的女性患者性交困难,明显影响了她的性关系,被转介到妇科诊所。使用外用雌激素乳膏和性咨询治疗均不成功。我们对她进行了两次粘膜下注射prp -非交联透明质酸,注射到前庭和阴道前壁粘膜的下三分之一,间隔一个月。第二次注射后1个月,患者报告性交困难明显减轻,FSFI总分改善。患者和她的丈夫在第二次注射后一个月的性满意度评分与治疗前评分相比均有改善。阴道粘膜检查显示粘膜厚度和完整性改善,润滑增加。prp -非交联透明质酸粘膜下注射可有效治疗与癌症治疗相关的阴道萎缩,性交相关的疼痛和性满足。
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引用次数: 0
Atypical presentation of vesicouterine fistula (Youssef’s syndrome) post-caesarean gossypiboma: a case report 剖宫产后膀胱外瘘(优素福综合征)的非典型表现:1例报告
Q4 Medicine Pub Date : 2023-04-17 DOI: 10.4081/uij.2023.305
A. Khalid, A. Alhassan, J. O. Ejembi, A. Abdulwahab-Ahmed
Vesicouterine fistula as described by Youssef manifests with amenorrhea, and cyclic haematuria (menouria) without urinary incontinence commonly following caesarean section. Other aetiologies have been reported for this disease. The post-caesarean section gossypiboma, a dual aetiology causing this condition is rare and can make its presentation atypical, thus posing a diagnostic dilemma. The clinical evaluation alone in the atypical presentation of the vesicouterine fistula is insufficient except complemented by imaging investigations and endoscopic examination of the related organs. We report a case of vesicouterine fistula that was managed initially as chronic pelvic inflammatory disease despite urinary incontinence until further evaluation including a transvaginal ultrasound scan and urethrocystoscopy raised an index of suspicion of a vesical mass suggestive of gossypiboma. The mass was confirmed to be a foreign body, an abdominal gauze pack, or gossypiboma. Its removal and repair of the vesicouterine fistula were associated with a satisfactory outcome.
Youssef描述的膀胱子宫瘘表现为闭经和周期性血尿(月经尿),通常在剖腹产后无尿失禁。这种疾病的其他病因也有报道。剖腹产后的棉质瘤是导致这种情况的双重病因,这种情况很少见,而且可能使其表现非典型,从而造成诊断困境。除非辅以影像学检查和相关器官的内镜检查,否则仅对膀胱外瘘的非典型表现进行临床评估是不够的。我们报告了一例膀胱外瘘,尽管尿失禁,但最初作为慢性盆腔炎进行治疗,直到包括经阴道超声扫描和尿道膀胱镜检查在内的进一步评估提高了怀疑膀胱肿块提示棉质瘤的指数。肿块被确认为异物、腹部纱布包或棉质瘤。其膀胱外瘘的切除和修复取得了令人满意的结果。
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引用次数: 0
Urinary tract infections in the intradetrusor onabotulinumtoxinA population etrusor内肉毒杆菌毒素A人群的尿路感染
Q4 Medicine Pub Date : 2023-04-17 DOI: 10.4081/uij.2023.304
Esme White, A. Brewin, T. Nitkunan
The aim of our study was to determine the incidence of Urinary Tract Infections (UTI) following intradetrusor onabotulinumtoxinA injections within our trust. This was a retrospective study of all patients who underwent intradetrusor onabotulinumtoxinA injections at our trust from August 2005 to 2015. Information was taken from our botulinum database, clinic letters and microbiology results. The primary outcome criterion was a positive urine culture together with symptoms suggestive of infection within 6 months post-procedure. A total of 290 intradetrusor onabotulinumtoxinA procedures were performed on 86 patients. The rate of UTI within 6 months following a procedure was 33%. There was a high resistance rate to our standard antibiotic prophylaxis, which was changed together with the addition of pre-procedure urine cultures and an on the day urine dipstick test. A re-audit was performed between January and June 2016 of 41 procedures and showed a reduction in UTI incidence to 20%. The rate of UTI post procedure within our trust was 33%. Following the implementation of multiple management protocol changes, a re-audit showed a reduction of UTI incidence to 20%.
我们研究的目的是确定尿路感染(UTI)的发生率在我们的信托信托内的肌内注射肉毒杆菌毒素。这是一项回顾性研究,研究对象是2005年8月至2015年在我们医院接受肌内肉毒杆菌毒素注射的所有患者。信息取自我们的肉毒杆菌数据库、临床信函和微生物学结果。主要预后标准为术后6个月内尿培养阳性并出现感染症状。86例患者共接受290例肌内肉毒杆菌毒素治疗。手术后6个月内尿路感染发生率为33%。我们的标准抗生素预防有很高的耐药率,这与术前尿液培养和当天尿液试纸试验一起改变。2016年1月至6月对41例手术进行了重新审计,结果显示尿路感染发生率降低了20%。我们信托的UTI术后发生率为33%。在实施多项管理方案变更后,重新审核显示尿路感染发生率降低至20%。
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引用次数: 0
Levator hiatal ballooning prevalence in pelvic organ prolapse patients and its relation to levator ani muscle strength 盆腔器官脱垂患者提肌裂孔膨出的发生率及其与提肌肌力的关系
Q4 Medicine Pub Date : 2022-12-28 DOI: 10.4081/uij.2022.293
F. Moegni, Andrew Yurius Christian
Ballooning of the levator hiatus is a unique phenomenon of hyperdistention seen during the Valsalva maneuver in Pelvic Organ Prolapse (POP) patients. Although it is related to the weakness of pelvic floor muscles, there is only limited evidence of its effect on Levator Ani Muscle (LAM) strength, especially in Indonesia. The aim of this study was to describe the prevalence of levator hiatal ballooning in POP patients and its effect on LAM strength. A cross-sectional study was done on POP patients at Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, from July 2019 to June 2021. Subjects who could not perform the Valsalva maneuver or perineometer and those having a history of perineal rupture were excluded. Subjects were grouped into hiatal ballooning and non-ballooning group based on the maximum hiatal genital length measured using ultrasound examination. Clinical characteristics, hiatal ballooning status, and LAM strength were compared between groups. A total of 99 subjects (47 ballooning and 52 non-ballooning) were recruited during the study. The prevalence of hiatal ballooning in POP patients was 47.5%. There was significantly lower LAM strength in the ballooning group measured by perineometer (p = 0.018). There was a significant relationship between the perineometer result and Modified Oxford Grading Scale result in both groups (p < 0.001). Lower LAM strength was observed in POP patients with hiatal ballooning.
在盆腔器官脱垂(POP)患者的Valsalva操作中,提肛肌裂孔膨胀是一种独特的高膨胀现象。虽然它与盆底肌肉无力有关,但只有有限的证据表明它对提肛肌(LAM)力量的影响,特别是在印度尼西亚。本研究的目的是描述POP患者提肌裂孔肿胀的患病率及其对LAM强度的影响。2019年7月至2021年6月,对印度尼西亚雅加达Cipto Mangunkusumo国立综合医院的POP患者进行了横断面研究。不能进行Valsalva手法或会阴计的受试者以及有会阴破裂史的受试者被排除在外。根据超声测量的裂孔生殖器最大长度分为裂孔膨化组和非裂孔膨化组。比较两组患者的临床特征、肺裂孔球囊状态及LAM强度。在研究期间共招募了99名受试者(47名气球和52名非气球)。POP患者裂孔肿胀的发生率为47.5%。球囊组LAM强度明显降低(p = 0.018)。两组患者围膜测量结果与改良牛津评分结果之间存在显著相关性(p < 0.001)。伴有裂孔水肿的POP患者LAM强度较低。
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引用次数: 0
Transobturator-tape outside in (TVT-O) as saviour for female stress urinary incontince without available cystoscope for gynecologist: A case series 外置式透膜(TVT-O)作为妇科医生无膀胱镜的女性压力性尿失禁的救星:一个病例系列
Q4 Medicine Pub Date : 2022-09-23 DOI: 10.4081/uij.2022.296
F. Bashir, Abdul Rouf Khawaja, Yaseer Dar, T. Dar, Javeed Magray
SUI affects quality of life. Ulmsten and Petros reported mid urethral sling operations using Tension-free Vaginal Tape (TVT) and Delorme used Transobturator Tape (TOT). Cystoscopy is often used in retropubic sling procedures to identify lower urinary tract injury. Cystoscopy protects patients and accurately identifies iatrogenic injuries. The goal is to evaluate the efficacy of a standard Trans-Obturator (TOT-O) mid urethral sling for female Stress Urinary Incontinence (SUI) without intraoperative cystoscopy. A total of 120 female SUI patients from 2014 to 2019 were studied. Stress-related incontinence and diaper use were preoperative variables. Under spinal anesthesia, the procedure improved stress incontinence, sexual dysfunction, complications, and overall satisfaction. All patients improved after the procedure, and 116 (96.6%) completely resolved. Post-operative complications included urinary retention in 3 patients (2.5%), increased daytime urinary frequency in 3 (2.5%), urge incontinence in 4 (3.33%), groin/thigh pain in 2 (1.66%), and local mesh excision for mesh erosion in 1 (0.83%). Open EPI software calculated insignificant p values for clinical profile and satisfaction with symptom resolution. Brief Index of SF for Women was used to assess sexual function. At 6-month followup, all patients were satisfied with sexual function. TOT-O technique for female stress urinary incontinence is easy to learn and reproducible for beginners.
SUI影响生活质量。Ulmsten和Petros报道了使用无张力阴道带(TVT)和Delorme使用transsoturator带(TOT)进行中尿道悬吊手术。膀胱镜检查常用于耻骨后吊带手术,以确定下尿路损伤。膀胱镜检查可保护患者并准确识别医源性损伤。目的是评估标准的经闭孔(TOT-O)中尿道吊带治疗女性压力性尿失禁(SUI)的疗效,无需术中膀胱镜检查。选取2014 - 2019年女性SUI患者120例。压力相关性尿失禁和尿布使用是术前变量。在脊髓麻醉下,手术改善了压力性尿失禁、性功能障碍、并发症和总体满意度。所有患者术后均有改善,其中116例(96.6%)完全缓解。术后并发症包括尿潴留3例(2.5%),日间尿频增加3例(2.5%),急迫性尿失禁4例(3.33%),腹股沟/大腿疼痛2例(1.66%),局部补片切除1例(0.83%)。开放式EPI软件计算的临床概况和症状解决满意度的p值不显著。使用女性SF指数(Brief Index of SF for Women)评估性功能。随访6个月,所有患者性功能均满意。TOT-O技术治疗女性压力性尿失禁容易学习,对初学者具有可重复性。
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引用次数: 0
Evaluation of the factors contributing to success of pelvic floor muscle training in stress urinary incontinence 影响压力性尿失禁盆底肌肉训练成功因素的评价
Q4 Medicine Pub Date : 2022-07-08 DOI: 10.4081/uij.2022.290
G. N. Hidayah, S. Hakim, F. Moegni, N. Ibrahim, B. Santoso, Suskhan Djusad, Tyas Priyatini, A. Meutia
Pelvic Floor Muscle Training (PFMT) is an effective, non-invasive, and cost-effective treatment for Stress Urinary Incontinence (SUI). However, its success rate varies. We evaluated the factors predicting success in PFMT, such as age, initial urinary leakage, initial pelvic floor muscle contraction strength, urethral hypermobility, and myostatin level. A nested case-control study was conducted at Dr. Cipto Mangunkusumo hospital between February and October 2021. We evaluated demographic characteristics, UDI-6 and IIQ-7 questionnaire scores, physical exam, pad weight test, urethral hypermobility ultrasound, perineometry, myostatin level, and we instructed the subjects in PFMT according to a guidebook. After 12 weeks of PFMT, we evaluated therapy success, defined as less than 3g on the pad weight test. The study involved 58 women: 5 subjects dropped out, 47 subjects reached treatment success, and 6 subjects did not reach treatment success. Following bivariate analysis, we found that initial pad weight was the only variable that was significantly associated with treatment success (p=0.001, 95% CI: 1.02 – 2.25). The PFMT success rate was 88.68%, and initial urine leakage lower than 6.5g predicts PMFT success with 80.9% sensitivity and 83.3% specificity (p=0.001, 95% CI1.02–2.25).
盆底肌肉训练(PFMT)是治疗压力性尿失禁(SUI)的一种有效、无创、成本效益高的治疗方法。然而,它的成功率各不相同。我们评估了预测PFMT成功的因素,如年龄、初次尿漏、初次盆底肌肉收缩强度、尿道高活动度和肌肉生长抑制素水平。2021年2月至10月,在Cipto Mangunkusumo医生医院进行了一项嵌套病例对照研究。我们评估了人口统计学特征、UDI-6和IIQ-7问卷得分、体检、垫重测试、尿道高活动度超声、会阴测量术、肌肉生长抑制素水平,并根据指南指导受试者进行PFMT。PFMT治疗12周后,我们评估了治疗成功率,定义为衬垫重量测试中小于3g。这项研究涉及58名女性:5名受试者退出,47名受试人员获得治疗成功,6名受试人未获得治疗成功。经过双变量分析,我们发现初始垫重是唯一与治疗成功率显著相关的变量(p=0.001,95%CI:1.02-2.25)。PFMT成功率为88.68%,初始尿漏量低于6.5g预测PMFT成功,敏感性为80.9%,特异性为83.3%(p=0.001,95%CI=1.02-2.25)。
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引用次数: 0
A retrospective analysis of 47 procedures using a bioresorbable polycaprolactone based injectable for the treatment of mild to moderate stress urinary incontinence in adult females 回顾性分析47例使用生物可吸收性聚己内酯注射剂治疗成年女性轻至中度应激性尿失禁的病例
Q4 Medicine Pub Date : 2022-06-10 DOI: 10.4081/uij.2022.283
Anđelo Mojsović, E. Koldewijn
Over the recent years, potential longterm complications of permanent implants for urinary incontinence has become a topic of debate. As a result there is an increasing interest in less invasive and bioresorbable procedures from both healthcare professional as well as patients that ideally can be performed in an out-patient setting. This brief report describes our initial results using a novel bioresorbable injectable product for the treatment of female mild to moderate stress urinary incontinence. The results show that the majority of patients respond well to treatment and remain continent for the initial 12 months following injection. Complication rate is low and consisted of mild and transient events. These initial results are promising and merit further investigation into using this procedure as first-choice after unsuccessful conservative treatments such as pelvic floor muscle therapy.
近年来,永久性植入物治疗尿失禁的潜在长期并发症已成为一个争论的话题。因此,医疗专业人员和患者对微创和生物可吸收的手术越来越感兴趣,这些手术理想情况下可以在门诊进行。这份简短的报告描述了我们使用一种新型生物可吸收注射产品治疗女性轻度至中度压力性尿失禁的初步结果。结果显示,大多数患者对治疗反应良好,在注射后的最初12个月内保持稳定。并发症发生率低,包括轻微和短暂事件。这些初步结果是有希望的,值得进一步研究在盆底肌肉治疗等保守治疗失败后将该手术作为首选。
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Urogynaecologia International Journal
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