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Evaluation of mandibular third molar for age estimation of Filipino population age 9 - 23 years. 菲律宾9 - 23岁人口下颌第三磨牙年龄评估。
Q3 Medicine Pub Date : 2020-05-15
J R Memorando

Objectives: The study aims to determine the correlation between dental age and chronologic age in the assessment of third molar development among Filipino patients aged 9 to 23 years seen in the Paediatric Dentistry Division (PDD) of the Philippine Children's Medical Centre (PCMC) between 2012-2017.

Materials and methods: 384 digital panoramic radiographs of Filipino patients (215 males and 169 females) were gathered. Right mandibular third molars were assessed using Modified Demirjian Scoring System. Mean Absolute Error, Percentage error and Correlation is determined between dental age (DA) and chronologic age (CA) of the population.

Results and conclusion: Initial development of the third molars is observed to begin at approximately 9 years of age and root completion commences at around 19 years of age. Using Spearman Rank-Order Correlation, a strong positive correlation between CA and DA was observed among the overall population (r=0.9518). The observed correlation was stronger among females (r=0.9595) compared to males (r=0.9445). All correlation coefficients were significant (p-value<0.0001). Low percentage error among males and females is observed indicating no significant difference between the CA and DA values of the population.

目的:本研究旨在确定2012-2017年菲律宾儿童医疗中心(PCMC)儿科牙科科(PDD) 9至23岁菲律宾患者第三磨牙发育评估中牙龄和年岁之间的相关性。材料与方法:收集菲律宾患者数字全景x线片384张(男215张,女169张)。采用改良Demirjian评分系统对右下颌第三磨牙进行评分。确定人口牙龄(DA)和年代学年龄(CA)之间的平均绝对误差、百分比误差和相关性。结果和结论:第三磨牙的初始发育大约在9岁开始,牙根发育大约在19岁开始。通过Spearman秩序相关分析,发现CA和DA在总体人群中呈显著正相关(r=0.9518)。与男性(r=0.9445)相比,女性(r=0.9595)的相关性更强。所有相关系数均显著(p值)
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引用次数: 0
Sex determination in a Brazilian sample from cranial morphometric parameters - a preliminary study. 从头颅形态测量参数确定巴西样本性别的初步研究。
Q3 Medicine Pub Date : 2020-05-15
C Sassi, A Picapedra, R Álvarez-Vaz, C Martins Schmidt, V Ulbricht, E Daruge Júnior, L Francesquini Júnior

Sex determination, which is based on the existence of dimorphism between specimens of the same species, plays an important role in the process of human identification. In the absence of pelvic elements, the skull appears to be the best sex indicator, and can also be submitted to quantitative or metric assessments. Eleven measurements were taken for this study, four in the sagittal plane and seven in the horizontal, in two groups of 186 skulls each, with 101 from males and 85 from females for those of the sagittal plane, and 100 and 86, respectively, for those concerning the horizontal, of subjects aged between 18 and 94 years at the time of death. The sample belongs to the Osteological and Tomographic Biobank Professor Doctor Eduardo Daruge of the Piracicaba Dental School of the University of Campinas. The aim of this research was to establish a reliable method to determine sex and elaborate mathematical prototypes capable of assisting in investigation or identification activities, in a preliminary study. Of the measures implemented (Lambda-Nasion, Lambda-Rhinion, Lambda-Nasospinale, Rhinion-Nasospinale, Zygomaxillare-Zygomaxillare, Lambda-Incisive Foramen, Lambda-Right Zygomaxillare, Lambda-Left Zygomaxillare, Basion-Incisive Foramen, Basion-Right Zygomaxillare and Basion-Left Zygomaxillare), only the Lambda-Nasospinale and Rhinion-Nasospinale in the sagittal plane, and the Zygomaxillare-Zygomaxillare and Lambda-Incisive Foramen in the horizontal plane, were significantly dimorphic. Two predictive mathematical models of sex were conceived for each pair of them: one of logistic regression and another of conditional inference trees, displaying accuracy rates of 78.5% and 77.42%, and of 68.28% and 72.04%, respectively. The authors concluded that there is the possibility to apply the aforementioned data in forensic anthropology as an auxiliary tool in investigation or identification tasks.

性别决定是建立在同一物种标本之间存在二态性的基础上的,在人类身份识别过程中起着重要作用。在没有骨盆元素的情况下,头骨似乎是最好的性别指标,也可以提交定量或度量评估。这项研究在两组186个头骨中进行了11次测量,4次在矢状面,7次在水平面,其中101个来自男性,85个来自女性,关于矢状面,分别有100和86个来自水平面,年龄在18至94岁之间的受试者死亡时。该样本属于坎皮纳斯大学皮拉西卡巴牙科学院的教授Eduardo Daruge。这项研究的目的是建立一种可靠的方法来确定性别,并在初步研究中制定能够协助调查或识别活动的数学原型。在所实施的措施(Lambda-Nasion、Lambda-Rhinion、lambda -鼻棘、rhino -鼻棘、颧骨-颧骨、lambda -右颧骨、lambda -左颧骨、基底-切口孔、基底-右颧骨和基底-左颧骨)中,只有矢状面上的lambda -鼻棘和鼻骨-鼻棘,以及水平面上的颧骨-颧骨和lambda -切口孔具有显著的二态性。对每一对性别预测模型分别建立了逻辑回归模型和条件推理树模型,准确率分别为78.5%和77.42%,68.28%和72.04%。作者的结论是,有可能将上述数据应用于法医人类学,作为调查或鉴定任务的辅助工具。
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引用次数: 0
Personal identification through digital photo superimposition of dental profile: a pilot study. 通过数字照片叠加牙齿轮廓的个人识别:一项试点研究。
Q3 Medicine Pub Date : 2019-12-30
V Santoro, F Mele, F Introna, A De Donno

The usefulness of teeth for personal identification lies mainly in their vast individual variability, making them virtually unique for every subject. Odontological identification represents a reliable and important complement to forensic inquiries, in particular in the event of unidentifiable human remains. However, this technique is based on the availability of ante-mortem records containing significant evidence. In the absence of dental records, the only available ante-mortem elements are often photographs. In the present study, dental profile photographs of selected smiling subjects were compared to the relevant plaster study models through digital image analysis. In order to ascertain the reliability of the technique, the comparison was carried out both in a homologous and heterologous manner with the Facecomp software. The results confirm the ability of Facecomp software to identify even the smallest variations in dental elements to reach a positive identification. The method is useful in forensic practice since a forensic inquiry may obtain plaster models from cadavers for comparison with photographs of missing people's anterior teeth.

牙齿对个人身份识别的用处主要在于它们巨大的个体差异,使得每个受试者的牙齿几乎都是独一无二的。牙学鉴定是对法医调查的可靠和重要补充,特别是在无法识别人类遗骸的情况下。然而,这种技术是基于含有重要证据的死前记录的可用性。在没有牙科记录的情况下,唯一可用的死前资料通常是照片。在本研究中,通过数字图像分析,将选择的微笑受试者的牙齿侧面照片与相关的石膏研究模型进行比较。为了确定该技术的可靠性,采用Facecomp软件进行同源和异源比较。结果证实了Facecomp软件能够识别牙齿元素中最小的变化,从而达到积极的识别。该方法在法医实践中是有用的,因为法医调查可以从尸体上获得石膏模型,以便与失踪人员的前牙照片进行比较。
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引用次数: 0
Accuracy of two dental age estimation methods in the Indian population - A meta-analysis of published studies. 两种牙龄估计方法在印度人口中的准确性-对已发表研究的荟萃分析。
Q3 Medicine Pub Date : 2019-12-30
H Prasad, N Kala

Background: Dental age estimation using radiographic methods have gained considerable attention in the recent past. Although several such methods exist, Demirjian's method and Willems' method are very popular and have been used extensively. Whether these methods are applicable to the Indian population is not known.

Methods: A search of Pubmed, Embase and Google Scholar search engines was done using specific keywords to identify studies using Demirjian's and Willems' methods in the Indian population. Studies published up to July 2018 were considered, and after thorough review, 20 eligible studies were identified. Meta-analysis of data obtained from these articles was conducted on 3668 children for Demirjian's method and 3144 children for Willems' method. The weighted mean differences for both of these methods at 95% confidence intervals were assessed to identify the accuracy of each method in predicting the chronological age.

Results: Demirjian's method was found to consistently overestimate the age in Indian population, irrespective of the gender. The overestimation was in the order of few months. Willems' method resulted in underestimation of the age, although this was comparatively minimal in the order of 30 to 40 days.

Conclusion: Willems' method produced more accurate age which was very close to the chronological age, both in boys and girls. In contrast, Demirjian's method suffered from marked overestimation. Willems' method appears to be more suited to use in the Indian population.

背景:近年来,利用放射学方法估计牙齿年龄已经引起了相当大的关注。虽然存在几种这样的方法,但Demirjian的方法和Willems的方法非常流行并被广泛使用。这些方法是否适用于印度人口尚不清楚。方法:使用特定关键词对Pubmed、Embase和Google Scholar搜索引擎进行搜索,以确定使用Demirjian和Willems的方法在印度人群中进行的研究。考虑到2018年7月之前发表的研究,经过彻底审查,确定了20项符合条件的研究。采用Demirjian方法对3668名儿童和Willems方法对3144名儿童进行meta分析。对这两种方法在95%置信区间的加权平均差异进行评估,以确定每种方法预测实足年龄的准确性。结果:发现Demirjian的方法始终高估了印度人口的年龄,而与性别无关。高估的时间大约是几个月。Willems的方法导致了对年龄的低估,尽管这在30到40天的顺序中是相对最小的。结论:Willems方法得到的年龄更准确,男孩和女孩的年龄都非常接近实足年龄。相比之下,Demirjian的方法明显被高估了。威廉姆斯的方法似乎更适合印度人使用。
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引用次数: 0
Patient autonomy as a necessary but limited ethical principle in shaping the dentist-patient relationship. 病人自主作为必要的,但有限的道德原则,在塑造牙医与病人的关系。
Q3 Medicine Pub Date : 2019-12-30
J Vm Welie

Today, the ethical and legal organization of the therapeutic relationship is determined in large extent by the principle of respect for patient autonomy or self-determination. From it, the patient derives important legally enforceable rights, most notably the right to consent to (or refuse) any proposed dental treatment. And yet, historically and indeed by its very nature, this principle is actually foreign to the health care context. Patients do not seek to defend themselves against their dentists in the same way that citizens need protection against a potentially tyrannical government. We will argue that the principle of patient autonomy sets important legal boundaries to the therapeutic relationship. But it does little to cement the relationship itself. Rather, it is the ethical principles of beneficence and non-maleficence that structure the dentist-patient relationship.

今天,治疗关系的伦理和法律组织在很大程度上是由尊重病人自主或自决的原则决定的。由此,患者获得了重要的法律上可执行的权利,最明显的是同意(或拒绝)任何拟议的牙科治疗的权利。然而,从历史上和本质上讲,这一原则实际上与医疗保健环境无关。病人不会像公民需要保护来对抗潜在的暴虐政府那样,寻求保护来对抗牙医。我们将论证病人自主原则为治疗关系设定了重要的法律界限。但这对巩固两国关系本身没有什么帮助。相反,是慈善和非恶意的伦理原则构成了牙医与病人的关系。
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引用次数: 0
Digital tooth reconstruction: An innovative approach in forensic odontology. 数字牙齿重建:法医牙科学的创新方法。
Q3 Medicine Pub Date : 2019-12-30
A Johnson, G Jani, A Pandey, N Patel

In mass disasters, accidents and crime investigations, where human remains are decomposed, charred or skeletonized, teeth may dislodge due to post-mortem loss or due to mishandling of evidence during the manipulation of skeletal and dental remains. Thus, the identification process is hampered due to the loss of dental evidence. In these situations, forensic tooth reconstruction may aid in the identification process. Forensic tooth reconstruction (FTR) refers to the process that aims to reconstruct the morphology of the missing tooth from the skeletal remains from the intra-alveolar morphology of the dental socket. The study is an innovative attempt to develop a digital approach to reconstruct three-dimensional (3D) printed tooth models through recording intra-alveolar morphology of empty dental sockets which simulate the teeth which are missing post-mortem. An experimental study was conducted on the human mandible, where using volumetric scanning, 3D scanning and printing techniques the tooth was reconstructed from the intra-alveolar morphology of the socket. Through metric analysis and qualitative congruency testing it was established that there was minimal discrepancy between natural tooth and 3D printed tooth. It was determined that teeth missing post-mortem do not necessarily invalidate the identification process. Digital FTR gives accurate results with minimum error.

在大规模灾害、事故和犯罪调查中,当人类遗骸腐烂、烧焦或骨骼化时,由于死后丢失或在操纵骨骼和牙齿遗骸过程中对证据处理不当,牙齿可能会脱落。因此,由于牙齿证据的丢失,鉴定过程受到阻碍。在这些情况下,法医牙齿重建可能有助于识别过程。法医牙齿重建(FTR)是指旨在从牙槽内的牙槽内形态重建骨骼残骸中缺失牙齿的形态的过程。该研究是一项创新的尝试,通过记录空牙槽槽内的形态来模拟死后缺失的牙齿,从而开发一种数字方法来重建三维(3D)打印牙齿模型。在人类下颌骨上进行了一项实验研究,利用体积扫描、3D扫描和打印技术,从牙槽内形态重建了牙齿。通过度量分析和定性一致性测试,确定了天然牙齿与3D打印牙齿之间的差异很小。他们认定,死后牙齿缺失并不一定会使鉴定过程无效。数字FTR以最小的误差提供准确的结果。
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引用次数: 0
Review of the dental treatment backlog of people with disabilities in Europe. 欧洲残疾人牙科治疗积压情况审查。
Q3 Medicine Pub Date : 2019-12-30
I Phlypo, L Janssens, E Palmers, D Declerck, L Marks

Aim: The present research aims at reviewing the oral health conditions and treatment needs of people with disabilities in Europe.

Methods: A comprehensive literature search was conducted using Medline and Embase with a timeframe from January 2008 until December 2017. Subsequently, a citation tracking was undertaken. Articles in English, French and Dutch were included.

Results: Forty-two articles were included. A variety of oral health problems and treatment needs was reported. More untreated carious lesions, less restorations, a higher number of extractions and less prosthetic rehabilitations were seen in people with disabilities compared with other individuals without disabilities. The oral hygiene level and the periodontal conditions were poor. Moreover, a higher risk of dental trauma, orthodontic problems and tooth wear were reported.

Discussion: Different determinants contribute to the oral health condition and treatment needs of people with disabilities. These determinants can be inherent in persons with a disability (biological factors), their lifestyle, the environment or the organization of oral health care. A treatment backlog was a common finding in people with disabilities. However, results need to be interpreted with caution because of the variety of people with disabilities included in this literature review. Proposed solutions can be put at the level of daily oral care, through oral health promotion programs and the creation of a supportive environment, but also at the level of dental attendance, facilitating the access to oral health care services and focusing the training of dental students and dentists.

Conclusion: This comprehensive review clearly shows a dental treatment backlog in people with disabilities. Solutions require efforts from the caregivers and dental professionals.

目的:本研究旨在回顾欧洲残疾人的口腔健康状况和治疗需求。方法:使用Medline和Embase进行综合文献检索,时间范围为2008年1月至2017年12月。随后,进行了引文跟踪。包括英文、法文和荷兰文的文章。结果:纳入42篇文献。报告了各种口腔健康问题和治疗需求。与其他没有残疾的人相比,残疾人中出现了更多未经治疗的龋齿病变,更少的修复,更多的拔牙次数和更少的假肢康复。口腔卫生水平和牙周状况较差。此外,据报道,牙外伤,正畸问题和牙齿磨损的风险更高。讨论:不同的决定因素影响着残疾人的口腔健康状况和治疗需求。这些决定因素可能是残疾人固有的(生物因素)、他们的生活方式、环境或口腔保健组织。治疗积压在残疾人中很常见。然而,研究结果需要谨慎解读,因为本文献综述中涉及的残疾人种类繁多。提出的解决办法可以放在日常口腔护理层面,通过口腔健康促进方案和创造一个支持性环境,也可以放在牙科护理层面,促进获得口腔保健服务,重点培训牙科学生和牙医。结论:这一全面的审查清楚地表明,在残疾人牙科治疗积压。解决方案需要护理人员和牙科专业人员的努力。
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引用次数: 0
Validation of the third molar maturity index (I3M): study of a Dominican Republic sample. 第三摩尔成熟度指数(I3M)的验证:对多米尼加共和国样品的研究。
Q3 Medicine Pub Date : 2019-12-30
L Gómez Jiménez, L A Velandia Palacio, S De Luca, Y Ramirez Vasquez, M Corominas Capellán, R Cameriere

This retrospective study aims to test the third molar maturity index (I3M) cut-off value of 0.08 for 18 years old in Dominican Republic population. Orthopantomograms of 513 subjects (284 females and 229 males) were evaluated, intra- and inter-observer agreement, ICC (intra-class correlation coefficient) values were 0.88% (95 % CI 0.86% to 0.91%), and 0.93% (95% CI 0.90% to 0.96%), for the intra- and inter-observer reliability, respectively. Accuracy in females was 0.96 (95% CI: 0.93-0.97); the sensitivity was 0.99 (95% CI: 0.96-0.99) and specificity was 0.92 (95% CI: 0.86-0.95). In males, the accuracy was 0.96 (95% CI: 0.93-0.98); the sensitivity was 0.94 (95% CI: 0.88-0.97) and specificity was 0.99 (95% CI: 0.95-0.99). The PPV (Positive Predictive Value) was 0.93 for females and 0.99 for males. The results of this study show that I3M can be used for discriminating adults from minors in Dominican Republic subjects around the legal age of 18 years old.

本回顾性研究的目的是测试第三磨牙成熟度指数(I3M)的临界值0.08为18岁的多米尼加共和国人口。513名受试者(284名女性和229名男性)的正位断层图被评估,观察者内部和观察者之间的一致性,ICC(类内相关系数)值分别为0.88% (95% CI 0.86%至0.91%)和0.93% (95% CI 0.90%至0.96%),用于观察者内部和观察者之间的信度。女性的准确率为0.96 (95% CI: 0.93-0.97);敏感性为0.99 (95% CI: 0.96 ~ 0.99),特异性为0.92 (95% CI: 0.86 ~ 0.95)。在男性中,准确率为0.96 (95% CI: 0.93-0.98);敏感性为0.94 (95% CI: 0.88 ~ 0.97),特异性为0.99 (95% CI: 0.95 ~ 0.99)。阳性预测值(PPV)女性为0.93,男性为0.99。本研究的结果表明,在多米尼加共和国,I3M可以用来区分成年人和未成年人的法定年龄在18岁左右。
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引用次数: 0
Oxytocin injection quality in Ethiopia: a post-marketing surveillance study in public and private facilities across three regions 埃塞俄比亚的催产素注射质量:在三个地区的公共和私人设施进行的上市后监测研究
Q3 Medicine Pub Date : 2019-12-01 DOI: 10.29392/joghr.3.e2019081
Pete Lambert, Tri-Hung Nguyen, Victoria L Oliver, Andrew J L McArthur, C. Goodall, A. Teklu, Bikila Bayissa, Zelalem Mamo, Betregiorgis Hailu Zegeye, M. Mcintosh
# BackgroundThe high prevalence of poor quality essential medicines in low and middle income countries (LMIC) presents considerable risks in terms of both health outcomes and economic cost. Oxytocin injection, the gold standard therapy for management of postpartum haemorrhage (PPH), presents a particular challenge in this area. Recent studies in India, Nigeria and DRC have identified product failure rates, in terms of low drug content, to be 41%, 74% and 80% respectively. Ethiopia bears a high burden of PPH with over 40% of maternal deaths being directly attributed to haemorrhagic causes. This study assessed the quality of oxytocin injection at points in the public and private supply chains to support national efforts to address PPH in Ethiopia.# MethodsThis study sampled oxytocin injection ampoules from 45 sites across Oromia, Afar regions and the administrative area of Addis Ababa. This included points along the public supply chain from the national point of entry for supplies through regional hubs to points of use (public and private facilities) in urban and rural areas. Collected samples were stored under refrigerated conditions until analysis for oxytocin content, known degradation products and microbiological quality.# ResultsNinety-six percent of ampoules passed all tests, while two samples (4%) contained less than the specified oxytocin content. Both samples were collected from rural facilities in Afar, a remote, poorly resourced region with a very hot climate. All supplies collected were sourced from European stringent regulatory approved (SRA) suppliers and, where storage conditions could be determined, approximately 95% of samples were stored in the refrigerator at the time of collection.# ConclusionsThe study indicates that oxytocin injection in the selected regions is generally of high quality and being stored appropriately. The failed samples detected in Afar suggest challenges remain around maintenance of refrigerated storage in least resourced settings. These findings contrast with recent results in other African countries and support the joint World Health Organization (WHO)/United Nations Children Fund/United Nations Population Fund statement that the availability of high quality oxytocin injection at the point of use is dependent on procurement of supplies from manufacturers approved by WHO or SRAs and storage at 2-8°C throughout the supply chain.
#背景:在低收入和中等收入国家,劣质基本药物的高流行率在健康结果和经济成本方面都构成了相当大的风险。催产素注射是产后出血(PPH)治疗的金标准疗法,在这一领域提出了特别的挑战。最近在印度、尼日利亚和刚果民主共和国进行的研究已经确定,按低药物含量计算,产品不合格率分别为41%、74%和80%。埃塞俄比亚承受着PPH的沉重负担,40%以上的孕产妇死亡直接归因于出血性原因。本研究评估了公共和私人供应链中催产素注射的质量,以支持埃塞俄比亚解决PPH问题的国家努力。方法本研究从奥罗米亚、阿法尔地区和亚的斯亚贝巴行政区域的45个地点取样催产素注射安瓿。这包括沿着公共供应链的各个点,从国家供应品入境点到区域中心,再到城市和农村地区的使用点(公共和私人设施)。收集的样品在冷藏条件下保存,直到分析催产素含量、已知降解产物和微生物质量。结果96%的安瓿通过了所有测试,而两个样品(4%)的催产素含量低于规定的水平。这两个样本都是从阿法尔的农村设施收集的,阿法尔是一个偏远、资源匮乏、气候非常炎热的地区。收集的所有样品均来自欧洲严格监管批准(SRA)的供应商,在可以确定储存条件的情况下,大约95%的样品在收集时储存在冰箱中。结论本研究表明,所选区域的催产素注射总体上质量较高,且保存适当。在阿法尔发现的不合格样品表明,在资源匮乏的环境中,维持冷藏储存仍然存在挑战。这些发现与其他非洲国家最近的结果形成对比,并支持世界卫生组织(世卫组织)/联合国儿童基金会/联合国人口基金的联合声明,即在使用点提供高质量的催产素注射取决于从世卫组织或SRAs批准的制造商处采购供应品,并在整个供应链中在2-8°C下储存。
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引用次数: 5
Cheiloscopy in individuals with Down syndrome and their nonsyndromic biological siblings. 唐氏综合症患者及其非综合症亲生兄弟姐妹的纤毛镜检查。
Q3 Medicine Pub Date : 2019-09-30
L C Cardoso Fernandes, J de Araújo Oliveira, P M Rabello, B M Santiago, M V Diniz de Carvalho, E P Soriano

The study aimed to carry out a comparative analysis between the lip print patterns in individuals with Down Syndrome and their nonsyndromic biological siblings. This was a cross-sectional blind study using an inductive approach and extensive direct observation procedures. A total of 68 cheiloscopic charts, named cheilograms, were divided into two groups (n=34), as follows: G1, including Down Syndrome individuals; and G2, including their nonsyndromic siblinggs. The convenience sample was selected in the city of João Pessoa, PB, Brazil. The following features were evaluated in eight labial regions called sub-quadrants: oral commissures (downturned, horizontal and upturned); lip thickness (thin, medium, thick and mixed); and labial grooves (I - complete vertical; I '- incomplete vertical; II - bifurcated; III - criss-cross; IV - reticular; or V - undefined). The data were analyzed by paired Student's t test and McNemar's Chi-square, with a 5% significance level. Most Down Syndrome individuals were found to have downturned oral commissures in 73.5% of cases, while their siblings showed a predominance of horizontal commissures in 73.5% of cases (p=0.009). There was no statistically significant difference for lip thickness between groups. In the analysis of labial groove patterns, Down Syndrome individuals (G1) showed a significant prevalence of the type I pattern (52.2%) as compared to their nonsyndromic siblings (30.1%) (p =< 0.001). Due to the tendency of having vertical labial groove patterns and downturned commissures, Down Syndrome individuals present cheiloscopic differences in relation to their nonsyndromic biological siblings, which suggests that syndromic genetics influences the development of these features. However, this may imply in a reduced potential of cheiloscopic identification due to the low divergence of labial phenotypes among Down Syndrome individuals.

该研究旨在对唐氏综合症患者及其非综合症亲生兄弟姐妹的唇印模式进行比较分析。这是一项横断面盲法研究,采用归纳法和大量直接观察程序。总共 68 张唇瓣图被命名为唇瓣图,分为以下两组(n=34):G1组包括唐氏综合症患者;G2组包括非唐氏综合症患者的兄弟姐妹。样本选自巴西 PB 省若昂-佩索阿市。在被称为亚象限的八个唇部区域对以下特征进行了评估:口腔突起(下翻、水平和上翻);唇厚度(薄、中、厚和混合);唇沟(I - 完全垂直;I '- 不完全垂直;II - 分叉;III - 十字形;IV - 网状;或 V - 未定义)。数据采用配对学生 t 检验和 McNemar's Chi-square 分析,显著性水平为 5%。结果发现,大多数唐氏综合症患者的口腔颊突下垂占 73.5%,而其兄弟姐妹的口腔颊突水平占 73.5%(P=0.009)。各组间嘴唇厚度的差异无统计学意义。在唇沟形态的分析中,唐氏综合征患者(G1)与非综合征的兄弟姐妹(30.1%)相比,I型唇沟形态(52.2%)的发生率更高(p =< 0.001)。由于唐氏综合征患者往往具有垂直唇沟纹和下弯的基突,因此他们的咀嚼镜与非综合征的兄弟姐妹相比存在差异,这表明综合征遗传影响了这些特征的形成。不过,由于唐氏综合症患者的唇表型差异较小,这可能意味着颊面镜鉴定的可能性降低。
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Journal of Forensic Odonto-Stomatology
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