Objectives: The study aims to determine the correlation between dental age and chronologic age in the assessment of third molar development among Filipino patients aged 9 to 23 years seen in the Paediatric Dentistry Division (PDD) of the Philippine Children's Medical Centre (PCMC) between 2012-2017.
Materials and methods: 384 digital panoramic radiographs of Filipino patients (215 males and 169 females) were gathered. Right mandibular third molars were assessed using Modified Demirjian Scoring System. Mean Absolute Error, Percentage error and Correlation is determined between dental age (DA) and chronologic age (CA) of the population.
Results and conclusion: Initial development of the third molars is observed to begin at approximately 9 years of age and root completion commences at around 19 years of age. Using Spearman Rank-Order Correlation, a strong positive correlation between CA and DA was observed among the overall population (r=0.9518). The observed correlation was stronger among females (r=0.9595) compared to males (r=0.9445). All correlation coefficients were significant (p-value<0.0001). Low percentage error among males and females is observed indicating no significant difference between the CA and DA values of the population.
{"title":"Evaluation of mandibular third molar for age estimation of Filipino population age 9 - 23 years.","authors":"J R Memorando","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The study aims to determine the correlation between dental age and chronologic age in the assessment of third molar development among Filipino patients aged 9 to 23 years seen in the Paediatric Dentistry Division (PDD) of the Philippine Children's Medical Centre (PCMC) between 2012-2017.</p><p><strong>Materials and methods: </strong>384 digital panoramic radiographs of Filipino patients (215 males and 169 females) were gathered. Right mandibular third molars were assessed using Modified Demirjian Scoring System. Mean Absolute Error, Percentage error and Correlation is determined between dental age (DA) and chronologic age (CA) of the population.</p><p><strong>Results and conclusion: </strong>Initial development of the third molars is observed to begin at approximately 9 years of age and root completion commences at around 19 years of age. Using Spearman Rank-Order Correlation, a strong positive correlation between CA and DA was observed among the overall population (r=0.9518). The observed correlation was stronger among females (r=0.9595) compared to males (r=0.9445). All correlation coefficients were significant (p-value<0.0001). Low percentage error among males and females is observed indicating no significant difference between the CA and DA values of the population.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"38 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880155/pdf/JFOS-38-1-26.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9418203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Sassi, A Picapedra, R Álvarez-Vaz, C Martins Schmidt, V Ulbricht, E Daruge Júnior, L Francesquini Júnior
Sex determination, which is based on the existence of dimorphism between specimens of the same species, plays an important role in the process of human identification. In the absence of pelvic elements, the skull appears to be the best sex indicator, and can also be submitted to quantitative or metric assessments. Eleven measurements were taken for this study, four in the sagittal plane and seven in the horizontal, in two groups of 186 skulls each, with 101 from males and 85 from females for those of the sagittal plane, and 100 and 86, respectively, for those concerning the horizontal, of subjects aged between 18 and 94 years at the time of death. The sample belongs to the Osteological and Tomographic Biobank Professor Doctor Eduardo Daruge of the Piracicaba Dental School of the University of Campinas. The aim of this research was to establish a reliable method to determine sex and elaborate mathematical prototypes capable of assisting in investigation or identification activities, in a preliminary study. Of the measures implemented (Lambda-Nasion, Lambda-Rhinion, Lambda-Nasospinale, Rhinion-Nasospinale, Zygomaxillare-Zygomaxillare, Lambda-Incisive Foramen, Lambda-Right Zygomaxillare, Lambda-Left Zygomaxillare, Basion-Incisive Foramen, Basion-Right Zygomaxillare and Basion-Left Zygomaxillare), only the Lambda-Nasospinale and Rhinion-Nasospinale in the sagittal plane, and the Zygomaxillare-Zygomaxillare and Lambda-Incisive Foramen in the horizontal plane, were significantly dimorphic. Two predictive mathematical models of sex were conceived for each pair of them: one of logistic regression and another of conditional inference trees, displaying accuracy rates of 78.5% and 77.42%, and of 68.28% and 72.04%, respectively. The authors concluded that there is the possibility to apply the aforementioned data in forensic anthropology as an auxiliary tool in investigation or identification tasks.
{"title":"Sex determination in a Brazilian sample from cranial morphometric parameters - a preliminary study.","authors":"C Sassi, A Picapedra, R Álvarez-Vaz, C Martins Schmidt, V Ulbricht, E Daruge Júnior, L Francesquini Júnior","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sex determination, which is based on the existence of dimorphism between specimens of the same species, plays an important role in the process of human identification. In the absence of pelvic elements, the skull appears to be the best sex indicator, and can also be submitted to quantitative or metric assessments. Eleven measurements were taken for this study, four in the sagittal plane and seven in the horizontal, in two groups of 186 skulls each, with 101 from males and 85 from females for those of the sagittal plane, and 100 and 86, respectively, for those concerning the horizontal, of subjects aged between 18 and 94 years at the time of death. The sample belongs to the Osteological and Tomographic Biobank Professor Doctor Eduardo Daruge of the Piracicaba Dental School of the University of Campinas. The aim of this research was to establish a reliable method to determine sex and elaborate mathematical prototypes capable of assisting in investigation or identification activities, in a preliminary study. Of the measures implemented (Lambda-Nasion, Lambda-Rhinion, Lambda-Nasospinale, Rhinion-Nasospinale, Zygomaxillare-Zygomaxillare, Lambda-Incisive Foramen, Lambda-Right Zygomaxillare, Lambda-Left Zygomaxillare, Basion-Incisive Foramen, Basion-Right Zygomaxillare and Basion-Left Zygomaxillare), only the Lambda-Nasospinale and Rhinion-Nasospinale in the sagittal plane, and the Zygomaxillare-Zygomaxillare and Lambda-Incisive Foramen in the horizontal plane, were significantly dimorphic. Two predictive mathematical models of sex were conceived for each pair of them: one of logistic regression and another of conditional inference trees, displaying accuracy rates of 78.5% and 77.42%, and of 68.28% and 72.04%, respectively. The authors concluded that there is the possibility to apply the aforementioned data in forensic anthropology as an auxiliary tool in investigation or identification tasks.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"38 1","pages":"8-17"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880152/pdf/JFOS-38-1-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9425184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The usefulness of teeth for personal identification lies mainly in their vast individual variability, making them virtually unique for every subject. Odontological identification represents a reliable and important complement to forensic inquiries, in particular in the event of unidentifiable human remains. However, this technique is based on the availability of ante-mortem records containing significant evidence. In the absence of dental records, the only available ante-mortem elements are often photographs. In the present study, dental profile photographs of selected smiling subjects were compared to the relevant plaster study models through digital image analysis. In order to ascertain the reliability of the technique, the comparison was carried out both in a homologous and heterologous manner with the Facecomp software. The results confirm the ability of Facecomp software to identify even the smallest variations in dental elements to reach a positive identification. The method is useful in forensic practice since a forensic inquiry may obtain plaster models from cadavers for comparison with photographs of missing people's anterior teeth.
{"title":"Personal identification through digital photo superimposition of dental profile: a pilot study.","authors":"V Santoro, F Mele, F Introna, A De Donno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The usefulness of teeth for personal identification lies mainly in their vast individual variability, making them virtually unique for every subject. Odontological identification represents a reliable and important complement to forensic inquiries, in particular in the event of unidentifiable human remains. However, this technique is based on the availability of ante-mortem records containing significant evidence. In the absence of dental records, the only available ante-mortem elements are often photographs. In the present study, dental profile photographs of selected smiling subjects were compared to the relevant plaster study models through digital image analysis. In order to ascertain the reliability of the technique, the comparison was carried out both in a homologous and heterologous manner with the Facecomp software. The results confirm the ability of Facecomp software to identify even the smallest variations in dental elements to reach a positive identification. The method is useful in forensic practice since a forensic inquiry may obtain plaster models from cadavers for comparison with photographs of missing people's anterior teeth.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442964/pdf/JFOS-37-3-21.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Dental age estimation using radiographic methods have gained considerable attention in the recent past. Although several such methods exist, Demirjian's method and Willems' method are very popular and have been used extensively. Whether these methods are applicable to the Indian population is not known.
Methods: A search of Pubmed, Embase and Google Scholar search engines was done using specific keywords to identify studies using Demirjian's and Willems' methods in the Indian population. Studies published up to July 2018 were considered, and after thorough review, 20 eligible studies were identified. Meta-analysis of data obtained from these articles was conducted on 3668 children for Demirjian's method and 3144 children for Willems' method. The weighted mean differences for both of these methods at 95% confidence intervals were assessed to identify the accuracy of each method in predicting the chronological age.
Results: Demirjian's method was found to consistently overestimate the age in Indian population, irrespective of the gender. The overestimation was in the order of few months. Willems' method resulted in underestimation of the age, although this was comparatively minimal in the order of 30 to 40 days.
Conclusion: Willems' method produced more accurate age which was very close to the chronological age, both in boys and girls. In contrast, Demirjian's method suffered from marked overestimation. Willems' method appears to be more suited to use in the Indian population.
{"title":"Accuracy of two dental age estimation methods in the Indian population - A meta-analysis of published studies.","authors":"H Prasad, N Kala","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Dental age estimation using radiographic methods have gained considerable attention in the recent past. Although several such methods exist, Demirjian's method and Willems' method are very popular and have been used extensively. Whether these methods are applicable to the Indian population is not known.</p><p><strong>Methods: </strong>A search of Pubmed, Embase and Google Scholar search engines was done using specific keywords to identify studies using Demirjian's and Willems' methods in the Indian population. Studies published up to July 2018 were considered, and after thorough review, 20 eligible studies were identified. Meta-analysis of data obtained from these articles was conducted on 3668 children for Demirjian's method and 3144 children for Willems' method. The weighted mean differences for both of these methods at 95% confidence intervals were assessed to identify the accuracy of each method in predicting the chronological age.</p><p><strong>Results: </strong>Demirjian's method was found to consistently overestimate the age in Indian population, irrespective of the gender. The overestimation was in the order of few months. Willems' method resulted in underestimation of the age, although this was comparatively minimal in the order of 30 to 40 days.</p><p><strong>Conclusion: </strong>Willems' method produced more accurate age which was very close to the chronological age, both in boys and girls. In contrast, Demirjian's method suffered from marked overestimation. Willems' method appears to be more suited to use in the Indian population.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"2-11"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442963/pdf/JFOS-37-3-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Today, the ethical and legal organization of the therapeutic relationship is determined in large extent by the principle of respect for patient autonomy or self-determination. From it, the patient derives important legally enforceable rights, most notably the right to consent to (or refuse) any proposed dental treatment. And yet, historically and indeed by its very nature, this principle is actually foreign to the health care context. Patients do not seek to defend themselves against their dentists in the same way that citizens need protection against a potentially tyrannical government. We will argue that the principle of patient autonomy sets important legal boundaries to the therapeutic relationship. But it does little to cement the relationship itself. Rather, it is the ethical principles of beneficence and non-maleficence that structure the dentist-patient relationship.
{"title":"Patient autonomy as a necessary but limited ethical principle in shaping the dentist-patient relationship.","authors":"J Vm Welie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Today, the ethical and legal organization of the therapeutic relationship is determined in large extent by the principle of respect for patient autonomy or self-determination. From it, the patient derives important legally enforceable rights, most notably the right to consent to (or refuse) any proposed dental treatment. And yet, historically and indeed by its very nature, this principle is actually foreign to the health care context. Patients do not seek to defend themselves against their dentists in the same way that citizens need protection against a potentially tyrannical government. We will argue that the principle of patient autonomy sets important legal boundaries to the therapeutic relationship. But it does little to cement the relationship itself. Rather, it is the ethical principles of beneficence and non-maleficence that structure the dentist-patient relationship.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"34-41"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442962/pdf/JFOS-37-3-34.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In mass disasters, accidents and crime investigations, where human remains are decomposed, charred or skeletonized, teeth may dislodge due to post-mortem loss or due to mishandling of evidence during the manipulation of skeletal and dental remains. Thus, the identification process is hampered due to the loss of dental evidence. In these situations, forensic tooth reconstruction may aid in the identification process. Forensic tooth reconstruction (FTR) refers to the process that aims to reconstruct the morphology of the missing tooth from the skeletal remains from the intra-alveolar morphology of the dental socket. The study is an innovative attempt to develop a digital approach to reconstruct three-dimensional (3D) printed tooth models through recording intra-alveolar morphology of empty dental sockets which simulate the teeth which are missing post-mortem. An experimental study was conducted on the human mandible, where using volumetric scanning, 3D scanning and printing techniques the tooth was reconstructed from the intra-alveolar morphology of the socket. Through metric analysis and qualitative congruency testing it was established that there was minimal discrepancy between natural tooth and 3D printed tooth. It was determined that teeth missing post-mortem do not necessarily invalidate the identification process. Digital FTR gives accurate results with minimum error.
{"title":"Digital tooth reconstruction: An innovative approach in forensic odontology.","authors":"A Johnson, G Jani, A Pandey, N Patel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In mass disasters, accidents and crime investigations, where human remains are decomposed, charred or skeletonized, teeth may dislodge due to post-mortem loss or due to mishandling of evidence during the manipulation of skeletal and dental remains. Thus, the identification process is hampered due to the loss of dental evidence. In these situations, forensic tooth reconstruction may aid in the identification process. Forensic tooth reconstruction (FTR) refers to the process that aims to reconstruct the morphology of the missing tooth from the skeletal remains from the intra-alveolar morphology of the dental socket. The study is an innovative attempt to develop a digital approach to reconstruct three-dimensional (3D) printed tooth models through recording intra-alveolar morphology of empty dental sockets which simulate the teeth which are missing post-mortem. An experimental study was conducted on the human mandible, where using volumetric scanning, 3D scanning and printing techniques the tooth was reconstructed from the intra-alveolar morphology of the socket. Through metric analysis and qualitative congruency testing it was established that there was minimal discrepancy between natural tooth and 3D printed tooth. It was determined that teeth missing post-mortem do not necessarily invalidate the identification process. Digital FTR gives accurate results with minimum error.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"12-20"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442960/pdf/JFOS-37-3-12.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Phlypo, L Janssens, E Palmers, D Declerck, L Marks
Aim: The present research aims at reviewing the oral health conditions and treatment needs of people with disabilities in Europe.
Methods: A comprehensive literature search was conducted using Medline and Embase with a timeframe from January 2008 until December 2017. Subsequently, a citation tracking was undertaken. Articles in English, French and Dutch were included.
Results: Forty-two articles were included. A variety of oral health problems and treatment needs was reported. More untreated carious lesions, less restorations, a higher number of extractions and less prosthetic rehabilitations were seen in people with disabilities compared with other individuals without disabilities. The oral hygiene level and the periodontal conditions were poor. Moreover, a higher risk of dental trauma, orthodontic problems and tooth wear were reported.
Discussion: Different determinants contribute to the oral health condition and treatment needs of people with disabilities. These determinants can be inherent in persons with a disability (biological factors), their lifestyle, the environment or the organization of oral health care. A treatment backlog was a common finding in people with disabilities. However, results need to be interpreted with caution because of the variety of people with disabilities included in this literature review. Proposed solutions can be put at the level of daily oral care, through oral health promotion programs and the creation of a supportive environment, but also at the level of dental attendance, facilitating the access to oral health care services and focusing the training of dental students and dentists.
Conclusion: This comprehensive review clearly shows a dental treatment backlog in people with disabilities. Solutions require efforts from the caregivers and dental professionals.
{"title":"Review of the dental treatment backlog of people with disabilities in Europe.","authors":"I Phlypo, L Janssens, E Palmers, D Declerck, L Marks","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>The present research aims at reviewing the oral health conditions and treatment needs of people with disabilities in Europe.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted using Medline and Embase with a timeframe from January 2008 until December 2017. Subsequently, a citation tracking was undertaken. Articles in English, French and Dutch were included.</p><p><strong>Results: </strong>Forty-two articles were included. A variety of oral health problems and treatment needs was reported. More untreated carious lesions, less restorations, a higher number of extractions and less prosthetic rehabilitations were seen in people with disabilities compared with other individuals without disabilities. The oral hygiene level and the periodontal conditions were poor. Moreover, a higher risk of dental trauma, orthodontic problems and tooth wear were reported.</p><p><strong>Discussion: </strong>Different determinants contribute to the oral health condition and treatment needs of people with disabilities. These determinants can be inherent in persons with a disability (biological factors), their lifestyle, the environment or the organization of oral health care. A treatment backlog was a common finding in people with disabilities. However, results need to be interpreted with caution because of the variety of people with disabilities included in this literature review. Proposed solutions can be put at the level of daily oral care, through oral health promotion programs and the creation of a supportive environment, but also at the level of dental attendance, facilitating the access to oral health care services and focusing the training of dental students and dentists.</p><p><strong>Conclusion: </strong>This comprehensive review clearly shows a dental treatment backlog in people with disabilities. Solutions require efforts from the caregivers and dental professionals.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"42-49"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442961/pdf/JFOS-37-3-42.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9463392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Gómez Jiménez, L A Velandia Palacio, S De Luca, Y Ramirez Vasquez, M Corominas Capellán, R Cameriere
This retrospective study aims to test the third molar maturity index (I3M) cut-off value of 0.08 for 18 years old in Dominican Republic population. Orthopantomograms of 513 subjects (284 females and 229 males) were evaluated, intra- and inter-observer agreement, ICC (intra-class correlation coefficient) values were 0.88% (95 % CI 0.86% to 0.91%), and 0.93% (95% CI 0.90% to 0.96%), for the intra- and inter-observer reliability, respectively. Accuracy in females was 0.96 (95% CI: 0.93-0.97); the sensitivity was 0.99 (95% CI: 0.96-0.99) and specificity was 0.92 (95% CI: 0.86-0.95). In males, the accuracy was 0.96 (95% CI: 0.93-0.98); the sensitivity was 0.94 (95% CI: 0.88-0.97) and specificity was 0.99 (95% CI: 0.95-0.99). The PPV (Positive Predictive Value) was 0.93 for females and 0.99 for males. The results of this study show that I3M can be used for discriminating adults from minors in Dominican Republic subjects around the legal age of 18 years old.
{"title":"Validation of the third molar maturity index (I3M): study of a Dominican Republic sample.","authors":"L Gómez Jiménez, L A Velandia Palacio, S De Luca, Y Ramirez Vasquez, M Corominas Capellán, R Cameriere","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This retrospective study aims to test the third molar maturity index (I3M) cut-off value of 0.08 for 18 years old in Dominican Republic population. Orthopantomograms of 513 subjects (284 females and 229 males) were evaluated, intra- and inter-observer agreement, ICC (intra-class correlation coefficient) values were 0.88% (95 % CI 0.86% to 0.91%), and 0.93% (95% CI 0.90% to 0.96%), for the intra- and inter-observer reliability, respectively. Accuracy in females was 0.96 (95% CI: 0.93-0.97); the sensitivity was 0.99 (95% CI: 0.96-0.99) and specificity was 0.92 (95% CI: 0.86-0.95). In males, the accuracy was 0.96 (95% CI: 0.93-0.98); the sensitivity was 0.94 (95% CI: 0.88-0.97) and specificity was 0.99 (95% CI: 0.95-0.99). The PPV (Positive Predictive Value) was 0.93 for females and 0.99 for males. The results of this study show that I3M can be used for discriminating adults from minors in Dominican Republic subjects around the legal age of 18 years old.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 3","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442959/pdf/JFOS-37-3-27.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9463391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.29392/joghr.3.e2019081
Pete Lambert, Tri-Hung Nguyen, Victoria L Oliver, Andrew J L McArthur, C. Goodall, A. Teklu, Bikila Bayissa, Zelalem Mamo, Betregiorgis Hailu Zegeye, M. Mcintosh
# Background The high prevalence of poor quality essential medicines in low and middle income countries (LMIC) presents considerable risks in terms of both health outcomes and economic cost. Oxytocin injection, the gold standard therapy for management of postpartum haemorrhage (PPH), presents a particular challenge in this area. Recent studies in India, Nigeria and DRC have identified product failure rates, in terms of low drug content, to be 41%, 74% and 80% respectively. Ethiopia bears a high burden of PPH with over 40% of maternal deaths being directly attributed to haemorrhagic causes. This study assessed the quality of oxytocin injection at points in the public and private supply chains to support national efforts to address PPH in Ethiopia. # Methods This study sampled oxytocin injection ampoules from 45 sites across Oromia, Afar regions and the administrative area of Addis Ababa. This included points along the public supply chain from the national point of entry for supplies through regional hubs to points of use (public and private facilities) in urban and rural areas. Collected samples were stored under refrigerated conditions until analysis for oxytocin content, known degradation products and microbiological quality. # Results Ninety-six percent of ampoules passed all tests, while two samples (4%) contained less than the specified oxytocin content. Both samples were collected from rural facilities in Afar, a remote, poorly resourced region with a very hot climate. All supplies collected were sourced from European stringent regulatory approved (SRA) suppliers and, where storage conditions could be determined, approximately 95% of samples were stored in the refrigerator at the time of collection. # Conclusions The study indicates that oxytocin injection in the selected regions is generally of high quality and being stored appropriately. The failed samples detected in Afar suggest challenges remain around maintenance of refrigerated storage in least resourced settings. These findings contrast with recent results in other African countries and support the joint World Health Organization (WHO)/United Nations Children Fund/United Nations Population Fund statement that the availability of high quality oxytocin injection at the point of use is dependent on procurement of supplies from manufacturers approved by WHO or SRAs and storage at 2-8°C throughout the supply chain.
{"title":"Oxytocin injection quality in Ethiopia: a post-marketing surveillance study in public and private facilities across three regions","authors":"Pete Lambert, Tri-Hung Nguyen, Victoria L Oliver, Andrew J L McArthur, C. Goodall, A. Teklu, Bikila Bayissa, Zelalem Mamo, Betregiorgis Hailu Zegeye, M. Mcintosh","doi":"10.29392/joghr.3.e2019081","DOIUrl":"https://doi.org/10.29392/joghr.3.e2019081","url":null,"abstract":"# Background\u0000\u0000The high prevalence of poor quality essential medicines in low and middle income countries (LMIC) presents considerable risks in terms of both health outcomes and economic cost. Oxytocin injection, the gold standard therapy for management of postpartum haemorrhage (PPH), presents a particular challenge in this area. Recent studies in India, Nigeria and DRC have identified product failure rates, in terms of low drug content, to be 41%, 74% and 80% respectively. Ethiopia bears a high burden of PPH with over 40% of maternal deaths being directly attributed to haemorrhagic causes. This study assessed the quality of oxytocin injection at points in the public and private supply chains to support national efforts to address PPH in Ethiopia.\u0000\u0000# Methods\u0000\u0000This study sampled oxytocin injection ampoules from 45 sites across Oromia, Afar regions and the administrative area of Addis Ababa. This included points along the public supply chain from the national point of entry for supplies through regional hubs to points of use (public and private facilities) in urban and rural areas. Collected samples were stored under refrigerated conditions until analysis for oxytocin content, known degradation products and microbiological quality.\u0000\u0000# Results\u0000\u0000Ninety-six percent of ampoules passed all tests, while two samples (4%) contained less than the specified oxytocin content. Both samples were collected from rural facilities in Afar, a remote, poorly resourced region with a very hot climate. All supplies collected were sourced from European stringent regulatory approved (SRA) suppliers and, where storage conditions could be determined, approximately 95% of samples were stored in the refrigerator at the time of collection.\u0000\u0000# Conclusions\u0000\u0000The study indicates that oxytocin injection in the selected regions is generally of high quality and being stored appropriately. The failed samples detected in Afar suggest challenges remain around maintenance of refrigerated storage in least resourced settings. These findings contrast with recent results in other African countries and support the joint World Health Organization (WHO)/United Nations Children Fund/United Nations Population Fund statement that the availability of high quality oxytocin injection at the point of use is dependent on procurement of supplies from manufacturers approved by WHO or SRAs and storage at 2-8°C throughout the supply chain.","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"5 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72538898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L C Cardoso Fernandes, J de Araújo Oliveira, P M Rabello, B M Santiago, M V Diniz de Carvalho, E P Soriano
The study aimed to carry out a comparative analysis between the lip print patterns in individuals with Down Syndrome and their nonsyndromic biological siblings. This was a cross-sectional blind study using an inductive approach and extensive direct observation procedures. A total of 68 cheiloscopic charts, named cheilograms, were divided into two groups (n=34), as follows: G1, including Down Syndrome individuals; and G2, including their nonsyndromic siblinggs. The convenience sample was selected in the city of João Pessoa, PB, Brazil. The following features were evaluated in eight labial regions called sub-quadrants: oral commissures (downturned, horizontal and upturned); lip thickness (thin, medium, thick and mixed); and labial grooves (I - complete vertical; I '- incomplete vertical; II - bifurcated; III - criss-cross; IV - reticular; or V - undefined). The data were analyzed by paired Student's t test and McNemar's Chi-square, with a 5% significance level. Most Down Syndrome individuals were found to have downturned oral commissures in 73.5% of cases, while their siblings showed a predominance of horizontal commissures in 73.5% of cases (p=0.009). There was no statistically significant difference for lip thickness between groups. In the analysis of labial groove patterns, Down Syndrome individuals (G1) showed a significant prevalence of the type I pattern (52.2%) as compared to their nonsyndromic siblings (30.1%) (p =< 0.001). Due to the tendency of having vertical labial groove patterns and downturned commissures, Down Syndrome individuals present cheiloscopic differences in relation to their nonsyndromic biological siblings, which suggests that syndromic genetics influences the development of these features. However, this may imply in a reduced potential of cheiloscopic identification due to the low divergence of labial phenotypes among Down Syndrome individuals.
{"title":"Cheiloscopy in individuals with Down syndrome and their nonsyndromic biological siblings.","authors":"L C Cardoso Fernandes, J de Araújo Oliveira, P M Rabello, B M Santiago, M V Diniz de Carvalho, E P Soriano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study aimed to carry out a comparative analysis between the lip print patterns in individuals with Down Syndrome and their nonsyndromic biological siblings. This was a cross-sectional blind study using an inductive approach and extensive direct observation procedures. A total of 68 cheiloscopic charts, named cheilograms, were divided into two groups (n=34), as follows: G1, including Down Syndrome individuals; and G2, including their nonsyndromic siblinggs. The convenience sample was selected in the city of João Pessoa, PB, Brazil. The following features were evaluated in eight labial regions called sub-quadrants: oral commissures (downturned, horizontal and upturned); lip thickness (thin, medium, thick and mixed); and labial grooves (I - complete vertical; I '- incomplete vertical; II - bifurcated; III - criss-cross; IV - reticular; or V - undefined). The data were analyzed by paired Student's t test and McNemar's Chi-square, with a 5% significance level. Most Down Syndrome individuals were found to have downturned oral commissures in 73.5% of cases, while their siblings showed a predominance of horizontal commissures in 73.5% of cases (p=0.009). There was no statistically significant difference for lip thickness between groups. In the analysis of labial groove patterns, Down Syndrome individuals (G1) showed a significant prevalence of the type I pattern (52.2%) as compared to their nonsyndromic siblings (30.1%) (p =< 0.001). Due to the tendency of having vertical labial groove patterns and downturned commissures, Down Syndrome individuals present cheiloscopic differences in relation to their nonsyndromic biological siblings, which suggests that syndromic genetics influences the development of these features. However, this may imply in a reduced potential of cheiloscopic identification due to the low divergence of labial phenotypes among Down Syndrome individuals.</p>","PeriodicalId":35728,"journal":{"name":"Journal of Forensic Odonto-Stomatology","volume":"37 2","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}