L. F. Pineda-Galindo, Leslie Moranchel-García, Magdalena Sánchez-Uribe, P. Ramírez-Mendoza, O. Vera-Lastra
{"title":"Púrpura de Henoch-Schönlein como manifestación inicial de mieloma múltiple","authors":"L. F. Pineda-Galindo, Leslie Moranchel-García, Magdalena Sánchez-Uribe, P. Ramírez-Mendoza, O. Vera-Lastra","doi":"10.24245/mim.v34i4.1579","DOIUrl":"https://doi.org/10.24245/mim.v34i4.1579","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47778541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Jaime Matta-Herrera, Luis Manuel Ballestas-Alarcón, A. Ramirez-Rincón
In South America, Colombia is secondly with number of diagnosed patients with diabetes mellitus (DM) and probably non-diagnostic patients. It has been calculated in Colombia 2 million people with diabetes mellitus, with a prevalence of 9.6% and it is the fifth position of causes of death and within the 10 causes that motivate the search for help. The new therapies with glucagon-like-1 receptors agonists (GLP-1 RAs) and SGLT2 inhibitors (SGLT2i) have been shown individually and through different mechanisms of action impact on the metabolic control and other variables such as blood pressure, lipid profile, weight, renal and cardiovascular protection. Type 2 diabetes mellitus treatment guides recommend for patients with dual therapy who continue HA1c out of goals, consider triple therapy if the patient has not achieved the goals after three months. A systematic search was made that included search engines such as Pubmed, Embase and Cochrane, resulting in 12 articles. More clinical studies should be done with the combination of GLP-1 RAs and SGLT2i in the context of patients with type 2 diabetes mellitus with poor metabolic control despite dual and triple therapies.
{"title":"Agonistas de GLP-1 más inhibidores de SGLT2. ¿Efectos cardioprotectores aditivos?","authors":"Gabriel Jaime Matta-Herrera, Luis Manuel Ballestas-Alarcón, A. Ramirez-Rincón","doi":"10.24245/mim.v34i4.1862","DOIUrl":"https://doi.org/10.24245/mim.v34i4.1862","url":null,"abstract":"In South America, Colombia is secondly with number of diagnosed patients with diabetes mellitus (DM) and probably non-diagnostic patients. It has been calculated in Colombia 2 million people with diabetes mellitus, with a prevalence of 9.6% and it is the fifth position of causes of death and within the 10 causes that motivate the search for help. The new therapies with glucagon-like-1 receptors agonists (GLP-1 RAs) and SGLT2 inhibitors (SGLT2i) have been shown individually and through different mechanisms of action impact on the metabolic control and other variables such as blood pressure, lipid profile, weight, renal and cardiovascular protection. Type 2 diabetes mellitus treatment guides recommend for patients with dual therapy who continue HA1c out of goals, consider triple therapy if the patient has not achieved the goals after three months. A systematic search was made that included search engines such as Pubmed, Embase and Cochrane, resulting in 12 articles. More clinical studies should be done with the combination of GLP-1 RAs and SGLT2i in the context of patients with type 2 diabetes mellitus with poor metabolic control despite dual and triple therapies.","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48094117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. López-Espinosa, Alpha Escamilla-Ruiz, Carlos Lijtszain-Sklar
{"title":"El Consejo Mexicano de Medicina Interna, AC. Gestión 2015-2018. Rendición de cuentas y transparencia. Informe y análisis","authors":"R. López-Espinosa, Alpha Escamilla-Ruiz, Carlos Lijtszain-Sklar","doi":"10.24245/MIM.V34I4.2279","DOIUrl":"https://doi.org/10.24245/MIM.V34I4.2279","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44453388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cartílago de tiburón: una panacea oncológica más","authors":"Guillermo Murillo-Domínguez","doi":"10.24245/MIM.V34I4.2041","DOIUrl":"https://doi.org/10.24245/MIM.V34I4.2041","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48658155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karla C Arana-Pazos, D. R. Benítez-Maldonado, Iván Meneses-Acero, Jorge Luis Narváez-Rivera, Carolina Guerrero-García, A. Rubio-Guerra
{"title":"Diferencias en el grosor de la grasa epicárdica en pacientes con diabetes mellitus tipo 2, prediabetes y sujetos no diabéticos","authors":"Karla C Arana-Pazos, D. R. Benítez-Maldonado, Iván Meneses-Acero, Jorge Luis Narváez-Rivera, Carolina Guerrero-García, A. Rubio-Guerra","doi":"10.24245/mim.v34i4.1969","DOIUrl":"https://doi.org/10.24245/mim.v34i4.1969","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68825672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ja Aldrete-Velasco, E. Chiquete, Ja. Rodríguez-García, R. Rincón-Pedrero, R. Correa-Rotter, R. García-Peña, E. Perusquía-Frías, JC Dávila‐Valero, C. Reyes-Zavala, J. Pedraza-Chávez
{"title":"Mortalidad por enfermedad renal crónica y su relación con la diabetes en México","authors":"Ja Aldrete-Velasco, E. Chiquete, Ja. Rodríguez-García, R. Rincón-Pedrero, R. Correa-Rotter, R. García-Peña, E. Perusquía-Frías, JC Dávila‐Valero, C. Reyes-Zavala, J. Pedraza-Chávez","doi":"10.24245/MIM.V34I4.1877","DOIUrl":"https://doi.org/10.24245/MIM.V34I4.1877","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46064490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Carrillo-Esper, M. D. J. Sánchez-Zúñiga, Nikolett I. Medveczky-Ordoñez, D. M. Carrillo-Córdova
Acute respiratory distress syndrome (ARDS) is an acute diffuse, inflammatory lung injury, leading to increased pulmonary vascular permeability, increased lung weight, loss of aerated lung tissue, hypoxemia, bilateral radiographic infiltrates, increased physiological dead space and intrapulmonary shunt and decrease lung compliance. ARDS was first described by Ashbaugh and Petty in 1967. For more than 20 years, there was no common definition of ARDS, and inconsistent definitions led to confusion and misdiagnosis. The 1994 The American European Consensus Conference (AECC) definition become accepted but had important limitations, since then, issues regarding the reliability and validity of this definition have emerged. The current definition is the Berlin one. This definition seems to be more accurate than the AECC definition and may facilitate prompt recognition of ARDS and promote protective ventilation strategy. The aim of this paper is to make a brief review of the evolution of the definition of ARDS at 50 years of its description.
{"title":"Evolución de la definición del síndrome de insuficiencia respiratoria aguda","authors":"R. Carrillo-Esper, M. D. J. Sánchez-Zúñiga, Nikolett I. Medveczky-Ordoñez, D. M. Carrillo-Córdova","doi":"10.24245/mim.v34i4.2092","DOIUrl":"https://doi.org/10.24245/mim.v34i4.2092","url":null,"abstract":"Acute respiratory distress syndrome (ARDS) is an acute diffuse, inflammatory lung injury, leading to increased pulmonary vascular permeability, increased lung weight, loss of aerated lung tissue, hypoxemia, bilateral radiographic infiltrates, increased physiological dead space and intrapulmonary shunt and decrease lung compliance. ARDS was first described by Ashbaugh and Petty in 1967. For more than 20 years, there was no common definition of ARDS, and inconsistent definitions led to confusion and misdiagnosis. The 1994 The American European Consensus Conference (AECC) definition become accepted but had important limitations, since then, issues regarding the reliability and validity of this definition have emerged. The current definition is the Berlin one. This definition seems to be more accurate than the AECC definition and may facilitate prompt recognition of ARDS and promote protective ventilation strategy. The aim of this paper is to make a brief review of the evolution of the definition of ARDS at 50 years of its description.","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45546478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parménides Guadarrama-Ortíz, J. C. Flores-Vázquez, Martha Carnalla-Cortés, J. A. Choreño-Parra
{"title":"Probióticos ¿coadyuvantes en el tratamiento médico?","authors":"Parménides Guadarrama-Ortíz, J. C. Flores-Vázquez, Martha Carnalla-Cortés, J. A. Choreño-Parra","doi":"10.24245/mim.v34i4.1878","DOIUrl":"https://doi.org/10.24245/mim.v34i4.1878","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48948841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE: To compare the rate of adherence to antiretroviral therapy in the first line in patients with depressive disorders vs those without depression. MATERIAL AND METHOD: A prospective study was done from January to June 2016 in patients from the HIV clinics of the Regional General Hospital No. 1 of IMSS, and the General Hospital Tacuba, in antiretroviral treatment with a first scheme, started more than six months ago, excluding patients with neurological disorders, different from depression, patients with diagnosis and/or previous treatment of depression. Patients answered the Beck questionnaire for depression and the SMAQ scale for adherence. RESULTS: 180 patients were evaluated with a first antiretroviral treatment regimen. It was found that 126 (70%) patients did not present depression, 36 (20%) presented depression, 15 (8.3%) presented moderate depression and 3 (1.7%) presented severe depression. Non-adherence was observed in 15.8% of patients without depression versus 55.5% of patients with depression (p = 0.01). The adherence of patients with depression was inversely proportional to the severity of the same. Regarding the viral load under the limit of suppression (< 40 copies/mL) in patients without depression, a higher proportion of patients with a viral load higher than 40 copies/mL was observed: 17.4% vs 15.8%, considered non-adherent by the SMAQ questionnaire. CONCLUSIONS: Adherence decreases with the severity of depression in patients, putting the effectiveness of antiretroviral treatment at risk.
目的:比较抑郁症患者与非抑郁症患者抗逆转录病毒治疗的一线依从率。材料和方法:2016年1月至6月，在IMSS第一地区综合医院艾滋病毒诊所和塔库巴综合医院的患者中进行了一项前瞻性研究，采用第一方案进行抗逆转录病毒治疗，六个多月前开始，排除神经系统疾病患者，不同于抑郁症，诊断和/或既往治疗过抑郁症的患者。患者回答了Beck抑郁问卷和SMAQ依从性量表。结果:180名患者接受了首次抗逆转录病毒治疗方案的评估。无抑郁126例(70%)，有抑郁36例(20%)，中度抑郁15例(8.3%)，重度抑郁3例(1.7%)。无抑郁患者中有15.8%出现不依从性，而抑郁患者中有55.5%出现不依从性(p = 0.01)。抑郁症患者的依从性与抑郁症的严重程度成反比。在无抑郁患者中，病毒载量低于抑制极限(< 40 copies/mL)的患者中，病毒载量高于40 copies/mL的患者比例更高:17.4% vs 15.8%，被SMAQ问卷视为非依从性。结论:依从性随着患者抑郁症严重程度的降低而降低，使抗逆转录病毒治疗的有效性面临风险。
{"title":"Asociación entre la severidad de la depresión y el apego al primer esquema de tratamiento antirretroviral","authors":"M. López-Hernández, Patricia Montoya-Escutia","doi":"10.24245/mim.v34i4.1828","DOIUrl":"https://doi.org/10.24245/mim.v34i4.1828","url":null,"abstract":"OBJECTIVE: To compare the rate of adherence to antiretroviral therapy in the first line in patients with depressive disorders vs those without depression. MATERIAL AND METHOD: A prospective study was done from January to June 2016 in patients from the HIV clinics of the Regional General Hospital No. 1 of IMSS, and the General Hospital Tacuba, in antiretroviral treatment with a first scheme, started more than six months ago, excluding patients with neurological disorders, different from depression, patients with diagnosis and/or previous treatment of depression. Patients answered the Beck questionnaire for depression and the SMAQ scale for adherence. RESULTS: 180 patients were evaluated with a first antiretroviral treatment regimen. It was found that 126 (70%) patients did not present depression, 36 (20%) presented depression, 15 (8.3%) presented moderate depression and 3 (1.7%) presented severe depression. Non-adherence was observed in 15.8% of patients without depression versus 55.5% of patients with depression (p = 0.01). The adherence of patients with depression was inversely proportional to the severity of the same. Regarding the viral load under the limit of suppression (< 40 copies/mL) in patients without depression, a higher proportion of patients with a viral load higher than 40 copies/mL was observed: 17.4% vs 15.8%, considered non-adherent by the SMAQ questionnaire. CONCLUSIONS: Adherence decreases with the severity of depression in patients, putting the effectiveness of antiretroviral treatment at risk.","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44996481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fármacos diuréticos: alteraciones metabólicas y cardiovasculares en el adulto mayor","authors":"J. E. Cruz-Aranda","doi":"10.24245/MIM.V34I4.1684","DOIUrl":"https://doi.org/10.24245/MIM.V34I4.1684","url":null,"abstract":"","PeriodicalId":35750,"journal":{"name":"Medicina Interna de Mexico","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41587636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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