Infectious Diseases: News, Opinions, Training最新文献

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Achievements in the study of molecular biological characteristics of different species within the genus Borrelia 疏螺旋体属不同种分子生物学特性的研究成果

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2023-01-01 DOI: 10.33029/2305-3496-2023-12-3-112-119

E.P. Sokolova, A.P. Khametova, L.V. Sudina, N.L. Pichurina

引用次数: 0

The effectiveness of the combined use of specific and nonspecific COVID-19 preventive measures 特异性和非特异性COVID-19预防措施联合使用的有效性

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2023-01-01 DOI: 10.33029/2305-3496-2023-12-3-55-60

I.V. Feldblum, T.M. Repin, M.Y. Devyatkov, M.A. Gileva, A.A. Kovtun

引用次数: 0

Validation of the russian version of the 4C Mortality Score and prediction of outcomes of severe COVID-19 俄文版4C死亡率评分的验证及重症COVID-19预后的预测

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-1-57-63

V. I. Vechorko, O. Averkov, N. Suponeva, M. Piradov, A. Zimin, Ja.G. Yusupova, A. Zaitsev, D. V. Grishin, N. V. Polekhina, A. V. Naminov, N. Ramchandani, S. Knight, M. Semple, E. M. Harrison

The aim of the study is to validate the Russian version of the 4C Mortality Score scale and evaluate its accuracy in predicting the outcomes of severe COVID-19. Material and methods. The staff of the Center for Validation of International Scales and Questionnaires of the Research Center of Neurology received official permission from the authors to conduct a validation study of the 4C Mortality Score scale in Russia. In the course of the work, the linguistic and cultural ratification of the scale was carried out and its Russian-language version was prepared. Psychometric properties (reliability and validity) The Russian-language version was evaluated on a group of 78 patients (37 of whom were men, aged 34 to 88 years) with a confirmed diagnosis of COVID-19, hospitalized in the City Clinical Hospital No. 15 named after O.M. Filatov (Moscow) in the period from June to August 2021. Results. The linguocultural adaptation of the 4C Mortality Score scale was successfully carried out. High levels of reliability were obtained (Spearman correlation coefficient ρ=0.91, p<0.0001;Cronbach's alpha α=0.73, p=0.0002;Cohen's kappa κ=0.85, p<0.0001). It is shown that the 4C Mortality Score scores have a significant correlation with the COVID-GRAM scores (r=0.72, p=0.002) and NEWS2 (r=0.54, p=0.004). Conclusion. As a result of the validation study, the official Russian version of the 4C Mortality Score scale was developed. It is recommended for use by medical professionals of various specialties at all stages of providing medical care to patients with COVID-19. The scale is available for download on the website of the Center for Validation of International Scales and Questionnaires of the Research Center of Neurology (https://www.neurology.ru/reabilitaciya/centr-validacii-mezhdunarodnyh-shkal-i-oprosnikov). © 2022 by the authors.

该研究的目的是验证俄罗斯版的4C死亡率评分量表，并评估其预测严重COVID-19结局的准确性。材料和方法。神经病学研究中心国际量表和问卷验证中心的工作人员获得了作者的正式许可，在俄罗斯进行4C死亡率评分量表的验证研究。在工作过程中，对该量表进行了语言和文化方面的批准，并编写了俄文版本。俄文版本对一组78名确诊为COVID-19的患者(其中37名男性，年龄34至88岁)进行了评估，这些患者于2021年6月至8月期间在以O.M. Filatov(莫斯科)命名的第15市临床医院住院。结果。4C死亡评分量表的语言适应得以成功实施。获得较高的信度(Spearman相关系数ρ=0.91, p<0.0001;Cronbach's α α=0.73, p=0.0002;Cohen's kappa κ=0.85, p<0.0001)。结果表明，4C死亡率评分与COVID-GRAM评分(r=0.72, p=0.002)和NEWS2评分(r=0.54, p=0.004)具有显著相关性。结论。作为验证研究的结果，俄罗斯官方版的4C死亡率评分量表被开发出来。建议不同专业的医疗专业人员在为COVID-19患者提供医疗护理的各个阶段使用。该量表可在神经内科研究中心国际量表及问卷验证中心网站(https://www.neurology.ru/reabilitaciya/centr-validacii-mezhdunarodnyh-shkal-i-oprosnikov)下载。©2022作者所有。

{"title":"Validation of the russian version of the 4C Mortality Score and prediction of outcomes of severe COVID-19","authors":"V. I. Vechorko, O. Averkov, N. Suponeva, M. Piradov, A. Zimin, Ja.G. Yusupova, A. Zaitsev, D. V. Grishin, N. V. Polekhina, A. V. Naminov, N. Ramchandani, S. Knight, M. Semple, E. M. Harrison","doi":"10.33029/2305-3496-2022-11-1-57-63","DOIUrl":"https://doi.org/10.33029/2305-3496-2022-11-1-57-63","url":null,"abstract":"The aim of the study is to validate the Russian version of the 4C Mortality Score scale and evaluate its accuracy in predicting the outcomes of severe COVID-19. Material and methods. The staff of the Center for Validation of International Scales and Questionnaires of the Research Center of Neurology received official permission from the authors to conduct a validation study of the 4C Mortality Score scale in Russia. In the course of the work, the linguistic and cultural ratification of the scale was carried out and its Russian-language version was prepared. Psychometric properties (reliability and validity) The Russian-language version was evaluated on a group of 78 patients (37 of whom were men, aged 34 to 88 years) with a confirmed diagnosis of COVID-19, hospitalized in the City Clinical Hospital No. 15 named after O.M. Filatov (Moscow) in the period from June to August 2021. Results. The linguocultural adaptation of the 4C Mortality Score scale was successfully carried out. High levels of reliability were obtained (Spearman correlation coefficient ρ=0.91, p<0.0001;Cronbach's alpha α=0.73, p=0.0002;Cohen's kappa κ=0.85, p<0.0001). It is shown that the 4C Mortality Score scores have a significant correlation with the COVID-GRAM scores (r=0.72, p=0.002) and NEWS2 (r=0.54, p=0.004). Conclusion. As a result of the validation study, the official Russian version of the 4C Mortality Score scale was developed. It is recommended for use by medical professionals of various specialties at all stages of providing medical care to patients with COVID-19. The scale is available for download on the website of the Center for Validation of International Scales and Questionnaires of the Research Center of Neurology (https://www.neurology.ru/reabilitaciya/centr-validacii-mezhdunarodnyh-shkal-i-oprosnikov). © 2022 by the authors.","PeriodicalId":36113,"journal":{"name":"Infectious Diseases: News, Opinions, Training","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69483945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaccination against COVID-19 in patients with inflammatory bowel diseases 炎症性肠病患者的COVID-19疫苗接种

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-3-125-129

A. Khasanova, M. Kostinov, I. Soloveva, A. P. Cherdantsev

The novel coronavirus infection (COVID-19) is characterized by a high incidence of damage not only to the bronchopulmonary system, but also to the gastrointestinal tract. The problem of patients with bowel diseases was reviewed in this research the context of the COVID-19 pandemic and the importance of vaccination this group of patients was reflected and approaches to it were described. The analysis of biomedical literature data on the problem of vaccination of patients with intestinal diseases against COVID-19 was carried out. © 2022 Sorbtsionnye i Khromatograficheskie Protsessy. All rights reserved.

新型冠状病毒感染(COVID-19)的特点是不仅对支气管肺系统，而且对胃肠道的损害发生率很高。本研究回顾了肠道疾病患者的问题，在COVID-19大流行的背景下，反映了这组患者接种疫苗的重要性，并描述了接种疫苗的方法。对肠道疾病患者COVID-19疫苗接种问题的生物医学文献资料进行分析。©2022 Sorbtsionnye i Khromatograficheskie protesessy。版权所有。

引用次数: 0

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection HIV感染患者尿结核分枝杆菌lam抗原检测的诊断价值

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-1-69-76

O. V. Dobronravova, S. Maksimov, N. N. Martynova, E. Kukhtevich, V. Zimina, N. A. Smirnov, A. Korovin, L.M. Sidoruk

引用次数: 0

The features of the liver function tests in patients with COVID-19 新冠肺炎患者肝功能检查特点分析

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-3-35-43

V. K. Fazylov, A. Oleynik, O. Abdullah, V. O. Akifiev, Ah. M. Fayyadh, G.C. Revathy

It is known that SARS-CoV-2 can cause liver damage due to the tropism of the virus to cholangiocytes and hepatocytes, the development of a cytokine storm, organ ischemia, aggravated in existing chronic liver disease and increasing during hospitalization, which probably can be related to the current drug intake or comorbidity. Evaluation of the frequency of abnormal liver function tests prior to the drugs administration in the hospital would allow to exclude a possible toxic effect. Aim of the study is to establish the prevalence and features of liver function tests (LFT) abnormalities and factors associated with in hospitalized patients with COVID-19. Methods. 248 adult patients with confirmed COVID-19 were admitted to the infectious diseases hospital were selected for an observational cross-sectional study. Patients clinical and laboratory characteristics, the frequency of liver damage are presented, and the relationship with such risk factors as age, gender, comorbidity, prehospital drug intake, COVID-19 severity, oxygen saturation (SaO2), need for admission in intensive care unit is assessed. Results. 41.2% of patients with COVID-19 had LFT abnormalities at the time of admission. Liver damage, represented mainly by cholestatic (76.9%) and hepatocellular (27.4%) patterns, was mild in the most cases. Patients over 50 years were more than twice as likely to show liver damage compared to younger patients (OR 2.24, 95% CI 1.03–4.9). There were no differences in the frequency of liver damage in patients depending on gender (OR 1.3, 95% CI 0.74–2.27), comorbidity (OR 0.91, 95% CI 0.5–1.6), pregnancy (OR 0.85, 95% CI 0.45–1.7), taking drugs before hospitalization (OR 1.3, 95% CI 0.6–2.7), including based on the drugs hepatotoxicity. The prevalence of LFT abnormalities is almost twice as high in patients with severe COVID-19 (OR 1.9, 95% CI 1.1–3.4), not associated with the level of hypoxia (OR 0.7, 95% CI 0.1–7.8), and the need for intensive care (OR 2.8, 95% CI 0.3–32.4). Conclusion. As a result of the study, it was found that at the time of admission to the hospital, most patients with COVID-19 have mild LFT abnormalities, which increase with age and severity of COVID-19. A cohort study should be conducted to overcome the limitations of the current cross-sectional study and draw more definitive conclusions. © Eco-Vector, 2022.

已知SARS-CoV-2可因病毒向胆管细胞和肝细胞的趋向性、细胞因子风暴的形成、器官缺血而引起肝损害，在已有的慢性肝病中加重，在住院期间加重，这可能与目前的药物摄入或合并症有关。在医院给药前评估肝功能异常检查的频率可以排除可能的毒性作用。本研究旨在了解COVID-19住院患者肝功能检查(LFT)异常的患病率、特征及其相关因素。方法:选择传染病医院收治的248例成年确诊COVID-19患者进行观察性横断面研究。介绍患者的临床和实验室特征、肝损害发生频率，并评估其与年龄、性别、合并症、院前药物摄入、COVID-19严重程度、血氧饱和度(SaO2)、重症监护病房入院需求等危险因素的关系。结果:41.2%的新冠肺炎患者入院时LFT异常。肝损害以胆汁淤积型(76.9%)和肝细胞型(27.4%)为主，多数为轻度。50岁以上的患者出现肝损伤的可能性是年轻患者的两倍多(OR 2.24, 95% CI 1.03-4.9)。不同性别(OR 1.3, 95% CI 0.74-2.27)、合并症(OR 0.91, 95% CI 0.5-1.6)、妊娠(OR 0.85, 95% CI 0.45-1.7)、住院前用药(OR 1.3, 95% CI 0.6-2.7)，包括基于药物肝毒性的患者发生肝损害的频率无差异。严重COVID-19患者的LFT异常发生率几乎是其两倍(OR 1.9, 95% CI 1.1-3.4)，与缺氧水平(OR 0.7, 95% CI 0.1-7.8)和重症监护需求(OR 2.8, 95% CI 0.3-32.4)无关。结论。研究发现，在入院时，大多数COVID-19患者有轻度LFT异常，随着年龄和COVID-19严重程度的增加而增加。应该进行队列研究，以克服当前横断面研究的局限性，得出更明确的结论。©Eco-Vector, 2022。

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引用次数: 0

The economic model of costs for realization of health care strategy for hepatitis C in the Republic Sakha (Yakutia) 萨哈共和国(雅库特)实施丙型肝炎保健战略的成本经济模型

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-3-104-111

S. S. Sleptsovа, Yu.I. Ivanets, S. Sleptsov, V. K. Semenova

引用次数: 0

Contemporary methods of laboratory diagnostics of tuberculosis. The detection of the pathogen and determination its drug sensitivity 现代肺结核实验室诊断方法。病原菌的检测及药敏测定

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-4-106-111

B. Borodulin, E. Eremenko, M. Uraksina, E. Borodulina

引用次数: 0

Risk factors for severe and prolonged acute respiratory viral infections in young patients 年轻患者严重和长期急性呼吸道病毒感染的危险因素

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-4-56-63

O. Rychkova, E. Kashuba, N. Rukina, N. V. Perminov, D. A. Sizov

引用次数: 0

Assessment of knowledge and attitudes of the adult population of the Republic of Bashkortostan to the prevention of influenza and acute respiratory viral infection 评估巴什科尔托斯坦共和国成年人口对预防流感和急性呼吸道病毒感染的知识和态度

Q4 Social Sciences

Infectious Diseases: News, Opinions, Training

Pub Date : 2022-01-01 DOI: 10.33029/2305-3496-2022-11-4-64-71

S. Ivakina, L. Gabdulkhakova, G. Khasanova, D.A. Valishin, Z. Abrarova, R.R. Kitapova, V.N. Dubrovin

引用次数: 0

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