Techniques and Innovations in Gastrointestinal Endoscopy最新文献

{"title":"Endoscopic Band Ligation With Sclerotherapy Versus Milligan–Morgan Hemorrhoidectomy for the Treatment of Mixed Hemorrhoids","authors":"Minghua Ai ,&nbsp;Weizheng Wang ,&nbsp;Jie Li ,&nbsp;Xiaoping Tan ,&nbsp;Qing Zhang","doi":"10.1016/j.tige.2025.250914","DOIUrl":"10.1016/j.tige.2025.250914","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>To compare the clinical efficacy of endoscopic band ligation with sclerotherapy (EBS) with that of Milligan–Morgan hemorrhoidectomy (MMH) in the treatment of mixed hemorrhoids.</div></div><div><h3>METHODS</h3><div>This study was a retrospective, single-center investigation conducted at the First Hospital of Yangtze University. From September 2022 to March 2023, 46 patients who underwent EBS for mixed hemorrhoids were selected in an observation group, whereas 32 patients who underwent MMH for mixed hemorrhoids were allocated to a control group. Surgical-related parameters and adverse events were compared between the 2 groups, and the relationship between the number of endoscopic bands used and pain levels was analyzed.</div></div><div><h3>RESULTS</h3><div>The observation group demonstrated significantly shorter surgical and hospitalization durations than the control group (<em>P &lt;</em> 0.05). Furthermore, the 2 groups showed decreased postoperative visual analog scale scores, with the observation group exhibiting consistently lower scores at 24 hours, 48 hours, and 1 week postoperatively (<em>P &lt;</em> 0.05). Additionally, visual analog scale scores in the observation group at 4 hour postsurgery were correlated with the number of endoscopic ligation bands applied (<em>R</em>² = 0.1253; <em>P</em> = 0.0158). No significant differences in postoperative anal swelling, overall efficacy, or patient satisfaction were observed between the 2 groups (all <em>P &gt;</em> 0.05). However, the observation group experienced significantly less intraoperative (0% vs 84.4%; <em>P</em> = 0.000) and postoperative bleeding (6.5% vs 34.4%; <em>P</em> = 0.002) and a lower postoperative infection rate (0% vs 9.4%; <em>P</em> = 0.034) than the control group.</div></div><div><h3>CONCLUSION</h3><div>EBS provides clinical efficacy comparable with that of MMH in the treatment of mixed hemorrhoids. Moreover, the EBS approach is a potentially less invasive and shorter surgical procedure with relatively reduced hospitalization time, lower complication risk, and faster recovery.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 2","pages":"Article 250914"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Endoscopic Role and Indications of Through-the-Scope Tack and Suture System for Gastrointestinal Closure","authors":"Andrew Canakis ,&nbsp;Abdulhameed Al-Sabban ,&nbsp;Shayan S. Irani","doi":"10.1016/j.tige.2024.09.005","DOIUrl":"10.1016/j.tige.2024.09.005","url":null,"abstract":"<div><div>The development of endoscopic closure devices has revolutionized management options for gastrointestinal defects. The endoscopists’ toolbox has expanded from through-the-scope clips to over-the-scope clips and over-the-scope suturing. The over-the-scope devices are somewhat limited by the target location, maneuverability, and need for device withdrawal for application. The introduction of a novel through-the-scope helix tack suture system enhances the toolbox for defect closure as this device can provide closure throughout the gastrointestinal tract without the need for endoscope withdrawal. Its user-friendly design and compatibility with standard endoscopes allows for complex tissues approximation in challenging locations. Since its approval by the Federal Drug Agency in December 2020, studies have investigated its utility for all types of defects, including perforations, leaks, fistulas, endoscopic resections sites, and even stent fixation. In this review, we will investigate the versatility of this device to understand its role in primary defect closure.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 1","pages":"Article 150898"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Ultrasound-Guided Pancreatic Fluid Collection Drainage and Pancreatic Ductal Drainage","authors":"Sridhar Sundaram ,&nbsp;Surinder Singh Rana","doi":"10.1016/j.tige.2025.250921","DOIUrl":"10.1016/j.tige.2025.250921","url":null,"abstract":"<div><div>Peripancreatic fluid collections (PFCs) are common complications associated with acute and chronic pancreatitis. Symptomatic PFCs need drainage, and endoscopic ultrasound (EUS) is the current standard of care. Various factors like the size, location, presence of debris in the collection, and general condition of the patient drive the choice of technique for EUS-guided transmural PFC drainage. While plastic stents were initially used, specially designed lumen-apposing and biflanged metal stents have revolutionized therapy for pancreatic necrotic collections. Minimally invasive approach in the form of endoscopic necrosectomy is now established as part of the step-up approach for performing debridement. PFCs are also often associated with disconnected pancreatic duct, which is a difficult situation to manage with evolving evidence. Pancreatic ductal obstruction due to strictures and stones represent indications for endoscopic intervention with stent placement to reduce ductal hypertension. EUS-guided pancreatic duct drainage represents an alternative in patients where endoscopic retrograde cholangiopancreatography fails or is not feasible. Either transmural or transpapillary approaches have been described. In this review, we discuss the role of EUS in drainage of PFCs along with technical tips for the same. We also discuss in detail technical steps and accessories and provide a critical appraisal on evidence for EUS-guided pancreatic duct drainage.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 3","pages":"Article 250921"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Sleeve Gastroplasty Reduces Atherosclerotic Cardiovascular Disease Risk: A Cohort Study Using Pooled Cohort Equations and Predicting Risk of Cardiovascular Disease Events Models","authors":"Ali Lahooti ,&nbsp;Chino Aneke-Nash ,&nbsp;Kate E. Johnson ,&nbsp;Anam Rizvi ,&nbsp;Muhammad U. Baig ,&nbsp;Alpana Shukla ,&nbsp;Carolyn Newberry ,&nbsp;Emily Smith ,&nbsp;Jude M. Sharaiha ,&nbsp;Mark Hanscom ,&nbsp;Kartik Sampath ,&nbsp;David L. Carr-Locke ,&nbsp;SriHari Mahadev ,&nbsp;Sonal Kumar ,&nbsp;Robert Schwartz ,&nbsp;Samuel M. Kim ,&nbsp;Reem Z. Sharaiha","doi":"10.1016/j.tige.2025.250942","DOIUrl":"10.1016/j.tige.2025.250942","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>Endoscopic sleeve gastroplasty (ESG) is a minimally invasive procedure for obesity, a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, its impact on cardiovascular risk remains underexplored. This study evaluates ESG’s effects on ASCVD risk and obesity-related comorbidities.</div></div><div><h3>METHODS</h3><div>In this cohort study, 168 adults with obesity (aged 30-79 years; body mass index, ≥30 kg/m² or ≥27 kg/m²; with comorbidities) underwent ESG at a single tertiary care facility from 2013 to 2024. Patients were evaluated at baseline and 12 months after procedure using the Pooled Cohort Equations (PCEs) for patients aged 40-79 years and the Predicting Risk of Cardiovascular Disease Events (PREVENT) equations for those aged 30-79 years. Changes in body weight, glycemic control, blood pressure, lipid profile (total cholesterol, low- and high-density lipoprotein cholesterol, triglycerides), and liver enzymes (alanine aminotransferase) were also analyzed.</div></div><div><h3>RESULTS</h3><div>Of the 168 patients (median age, 48 years; 74% female; body mass index, 36.0 kg/m²), 129 and 159 met inclusion criteria for PCEs and PREVENT equations, respectively. At 12 months, median PCEs ASCVD risk score decreased from 3.3% to 3.0% (21% reduction, <em>P</em> &lt; 0.001), while the PREVENT 10-year cardiovascular disease risk score declined from 3.1% to 2.4% (20% reduction; <em>P</em> &lt; 0.001), with similar reductions in 30-year risk scores and greater improvements in high/intermediate-risk patients and those aged &gt;50 years. Patients achieved a median total body weight loss of 13.5% (IQR, 8.1%-18.6%), with significant metabolic improvements, and &gt;80% experienced diabetes resolution. There was 1 (0.6%) moderate adverse event.</div></div><div><h3>CONCLUSION</h3><div>Adults who underwent ESG showed significant improvements in ASCVD risk and obesity-related comorbidities at 12 months after procedure. These findings suggest that ESG may be an effective intervention for managing obesity and mitigating cardiovascular risk in patients with obesity. ClincialTrials.gov identifier: NCT04494048.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 4","pages":"Article 250942"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traction-Assisted Endoscopic Submucosal Dissection of Colonic Lesions: A North American Experience","authors":"Farid Abushamat,&nbsp;Fares Ayoub,&nbsp;Mai A. Khalaf,&nbsp;Tara Keihanian,&nbsp;Salmaan Jawaid,&nbsp;Mohamed O. Othman","doi":"10.1016/j.tige.2024.250900","DOIUrl":"10.1016/j.tige.2024.250900","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>Traction-assisted endoscopic submucosal dissection (TA-ESD) is a proposed technique to improve the efficiency of endoscopic submucosal dissection (ESD). Multiple studies primarily from Asian centers yielded mixed results in terms of procedure time, en bloc resection rate, and R0 resection rate of TA-ESD in comparison with those of conventional endoscopic submucosal dissection (C-ESD). We performed the first comparison of TA-ESD with C-ESD at a high-volume North American center.</div></div><div><h3>METHODS</h3><div>This was a retrospective cohort-matched study of all patients who underwent colonic ESD at a single center in the United States by a single operator. The study group were patients who underwent TA-ESD and were matched with a C-ESD case on a 1:1 basis based upon location within the colon, lesion size, and scope stabilization device usage. The baseline characteristics and procedure-related outcomes were compared between the groups.</div></div><div><h3>RESULTS</h3><div>In total, 138 colonic ESD cases were included (69 TA-ESD and 69 C-ESD). There were no significant differences in the baseline characteristics between the groups. Mean procedure time was 91.0 minutes (SD: 32.5) for TA-ESD and 85.4 minutes (SD: 39.3) for C-ESD (<em>P</em> = 0.36). En bloc resection was achieved in 69 (100%) of the TA-ESDs and 67 (97.1%) of the C-ESDs (<em>P</em> = 0.15). R0 resection was achieved in 52 (75.4%) of the TA-ESDs and 48 (69.6%) of the C-ESDs (<em>P</em> = 0.45).</div></div><div><h3>CONCLUSION</h3><div>We did not show a significant difference in procedure time, en bloc resection, R0 resection, or adverse events. Further randomized prospective studies that are sufficiently powered and stratified by operator experience level are needed to further elucidate the utility of the technique.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 1","pages":"Article 250900"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover","authors":"","doi":"10.1016/S2590-0307(25)00032-7","DOIUrl":"10.1016/S2590-0307(25)00032-7","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 3","pages":"Article 250937"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reopenable Clip-Over-the-Line Method for Troubleshooting Iatrogenic Gastrointestinal Perforations","authors":"Takeshi Yasuda,&nbsp;Narutoshi Ando,&nbsp;Tamae Hashimoto,&nbsp;Yoshiaki Kanai,&nbsp;Yoichi Sakamoto,&nbsp;Yuki Endo,&nbsp;Tomohiro Soda,&nbsp;Takako Akazawa,&nbsp;Tsuguhiro Matsumoto,&nbsp;Norihito Yamauchi,&nbsp;Akira Muramatsu,&nbsp;Hiromu Kutsumi","doi":"10.1016/j.tige.2024.250901","DOIUrl":"10.1016/j.tige.2024.250901","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 1","pages":"Article 250901"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy and Safety of Needle-Knife Fistulotomy vs Standard Cannulation: A Practical Randomized Controlled Trial","authors":"Aleksey Novikov ,&nbsp;Shuji Mitsuhashi ,&nbsp;Muhammad Hassaan Bashir ,&nbsp;Mena Bakhit ,&nbsp;Ian Holmes ,&nbsp;Alexander Schlachterman ,&nbsp;Austin Chiang ,&nbsp;David Loren ,&nbsp;Thomas Kowalski","doi":"10.1016/j.tige.2025.250941","DOIUrl":"10.1016/j.tige.2025.250941","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>Current literature suggests that needle-knife fistulotomy (NKF) technique should be reserved for expert advanced endoscopists. The aim of this study was to evaluate the efficacy and safety of NKF compared with those of standard cannulation (SC) for primary biliary access performed by advanced endoscopists with a range of experience, including advanced endoscopy trainees.</div></div><div><h3>METHODS</h3><div>In total, 186 patients were randomly assigned to either NKF or SC as means of primary biliary access and 137 patients were included in the final analysis (clinicaltrials.gov; NCT06694038). The primary outcome was incidence of post–endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Secondary outcomes were biliary access success, time to biliary access, incidence of bleeding, and incidence of perforation.</div></div><div><h3>RESULTS</h3><div>Of the 137 procedures included in the study, 99 (72.3%) were carried out by advanced endoscopy trainees under supervision, 26 (19.0%) by advanced endoscopists without significant previous NKF experience, and 12 (8.8%) by an experienced advanced endoscopist with expertise in NKF. In the group that was randomized to SC, 6 (8.22%) patients developed pancreatitis vs 5 (7.81%) patients randomized to NKF arm (<em>P</em> = 0.93). Average time to biliary access within 20 minutes was significantly shorter with SC at 268 seconds (95% CI, 198-338 seconds) vs 380 seconds (95% CI, 292-466 seconds; <em>P</em> &lt; 0.05) in the NKF arm.</div></div><div><h3>CONCLUSION</h3><div>NKF is a safe and effective technique for primary biliary access during ERCP performed by advanced endoscopists with a wide range of experience, with post-ERCP pancreatitis equivalent to SC. NKF, in this study, took slightly longer than SC to achieve bile duct access. Use of either or both techniques resulted in a 100% successful bile duct cannulation in patients with favorable anatomy.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 4","pages":"Article 250941"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144865231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Patients’ Current Acceptability of Artificial Intelligence During Colonoscopy for Polyp Detection: A Single-Center Study","authors":"Kathryn A. Schmidt ,&nbsp;Shubham Sood ,&nbsp;Saam Dilmaghani ,&nbsp;Cadman Leggett ,&nbsp;Ross Dierkhising ,&nbsp;Mayank Goyal ,&nbsp;Barbara A. Barry ,&nbsp;Xuan Zhu ,&nbsp;Nayantara Coelho-Prabhu","doi":"10.1016/j.tige.2024.250905","DOIUrl":"10.1016/j.tige.2024.250905","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>Research into potential applications of artificial intelligence (AI) in healthcare have witnessed a meteoric rise. A primary application in gastroenterological care is colonoscopy. Before AI tools become ubiquitous in healthcare, it is critical to appreciate the perspective of the potential beneficiaries, particularly patients. This study evaluated patient acceptability of AI in colonoscopy, particularly for polyp detection and diagnosis.</div></div><div><h3>METHODS</h3><div>In this cross-sectional survey study, patients undergoing outpatient colon cancer screening or surveillance colonoscopies at Mayo Clinic, Rochester, from September 2023 to February 2024 completed an electronic self-administered survey via tablet computer including questions regarding AI in colonoscopy. The primary outcome was patient perspectives on AI, and secondary outcomes included patient factors influencing their perspective. Statistical analyses were performed using Pearson's chi-square test and ordinal logistic regression.</div></div><div><h3>RESULTS</h3><div>Five hundred eight participants completed the survey. Younger age, male gender, and higher education were associated with higher AI familiarity and perceived importance, while males and those who believed in AI's positive outcomes were more comfortable with AI-assisted polyp detection.</div></div><div><h3>CONCLUSION</h3><div>This study is the first to assess patient perceptions of AI in colonoscopy. While patients generally believe AI can improve health outcomes, there is uncertainty about its current use, indicating a gap in knowledge and awareness. Key findings highlight that beliefs in AI's efficacy are linked to increased comfort with AI-assisted procedures, with significant demographic variations in perceptions, particularly across gender, age, and education. Addressing disparities through targeted education and transparent communication is crucial for fostering patient acceptance and trust in AI-assisted colonoscopy.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 2","pages":"Article 250905"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Cleansing Solution for High-Quality Upper Gastrointestinal Endoscopy: A Multicenter Randomized Controlled Trial","authors":"Noemi Gualandi ,&nbsp;Giulia Gibiino ,&nbsp;Giuliano Francesco Bonura ,&nbsp;Matteo Secco ,&nbsp;Paola Soriani ,&nbsp;Alessandro Cucchetti ,&nbsp;Cecilia Binda ,&nbsp;Valentina Zadro ,&nbsp;Pablo Cortegoso Valdivia ,&nbsp;Paolo Biancheri ,&nbsp;Mauro Manno ,&nbsp;Carlo Fabbri","doi":"10.1016/j.tige.2025.250928","DOIUrl":"10.1016/j.tige.2025.250928","url":null,"abstract":"<div><h3>BACKGROUND AND AIMS</h3><div>Esophagogastroduodenoscopy (EGD) is the gold standard examination for upper gastrointestinal (GI) disease diagnosis; however, intraluminal bubbles and mucus may reduce visibility. Mucolytic and tensioactive agents before EGD improve gastric visualization. We compared the efficacy of a novel cleansing preparation vs fasting on upper GI tract visualization during EGD.</div></div><div><h3>METHODS</h3><div>We conducted a multicenter, prospective, randomized controlled trial on consecutive adult outpatients undergoing EGD. Patients were randomized 1:1 to drink 50 mL of simethicone 150 mg, N-acetylcysteine 250 mg, and 10% acetic acid solution (Lumevis, Biofarmatec srl, Palermo, Italy) before the EGD or to fasting. The primary outcome was overall mucosal vision quality score, defined as the sum of 1-10 visual analog scale scores (0 = no visualization; 10 = perfect visualization) for each segment (esophagus, stomach, and duodenum) before washing. Secondary outcomes included adverse event rate, patient satisfaction, and EGD duration.</div></div><div><h3>RESULTS</h3><div>Patients were randomized to cleansing solution (<em>n</em> = 60) or fasting (<em>n</em> = 60). Cleansing preparation administration before EGD was associated with a higher overall mucosal vision quality score compared with fasting only (median visual analog scale score 23 [range, 21-25] vs 19 [range, 16-23], <em>P</em> = 0.001). No adverse events were reported in both groups. Patient satisfaction and EGD duration were similar between the cleansing preparation and fasting only.</div></div><div><h3>CONCLUSION</h3><div>Compared with fasting only, the administration of this novel cleansing solution was associated with improved mucosal visualization of the upper GI tract.</div></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"27 3","pages":"Article 250928"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}