首页 > 最新文献

Current Treatment Options in Allergy最新文献

英文 中文
Innovations and Emerging Therapies in Atopic Dermatitis Part 1. 特应性皮炎的创新和新疗法1。
IF 1.9 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2025-01-01 Epub Date: 2025-05-07 DOI: 10.1007/s40521-025-00390-3
Robyn Okereke, Eric Simpson

Purpose of review: The purpose of this review is to discuss the innovative aspects of present and newer therapies used for the treatment of AD, as well as to highlight the characteristics of emerging treatments. We also compare alternative systemic therapies. The novelties surrounding systemic therapies will be highlighted in this first review (part 1), while innovations in topical therapies will be discussed in a subsequent review (part 2).

Recent findings: The treatment landscape of atopic dermatitis has been quickly evolving in recent history. The treatment framework of AD is shifting from broad suppression of the inflammatory response to targeted molecular therapy.

Summary: Overall, this therapeutic shift does appear to correlate with a superior efficacy and safety profile, though we also highlight encountered shortcomings when assessing long-term and real-world data of systemic therapies. Despite significant recent advances, future studies are needed to optimize formulations and performance of systemic therapies for AD.

综述目的：本综述的目的是讨论用于治疗阿尔茨海默病的现有和新疗法的创新方面，并强调新兴疗法的特点。我们还比较了不同的全身疗法。在第一篇综述（第1部分）中，将重点介绍全身疗法的创新，而局部疗法的创新将在随后的综述（第2部分）中讨论。最近的研究结果：特应性皮炎的治疗前景在最近的历史中迅速发展。阿尔茨海默病的治疗框架正在从广泛抑制炎症反应转向靶向分子治疗。总结：总的来说，这种治疗方法的转变似乎与优越的疗效和安全性相关，尽管我们也强调了在评估全身治疗的长期和实际数据时遇到的缺点。尽管最近取得了重大进展，但需要进一步的研究来优化阿尔茨海默病全身治疗的配方和性能。
{"title":"Innovations and Emerging Therapies in Atopic Dermatitis Part 1.","authors":"Robyn Okereke, Eric Simpson","doi":"10.1007/s40521-025-00390-3","DOIUrl":"10.1007/s40521-025-00390-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose of this review is to discuss the innovative aspects of present and newer therapies used for the treatment of AD, as well as to highlight the characteristics of emerging treatments. We also compare alternative systemic therapies. The novelties surrounding systemic therapies will be highlighted in this first review (part 1), while innovations in topical therapies will be discussed in a subsequent review (part 2).</p><p><strong>Recent findings: </strong>The treatment landscape of atopic dermatitis has been quickly evolving in recent history. The treatment framework of AD is shifting from broad suppression of the inflammatory response to targeted molecular therapy.</p><p><strong>Summary: </strong>Overall, this therapeutic shift does appear to correlate with a superior efficacy and safety profile, though we also highlight encountered shortcomings when assessing long-term and real-world data of systemic therapies. Despite significant recent advances, future studies are needed to optimize formulations and performance of systemic therapies for AD.</p>","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"12 ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovations and Emerging Therapies in Atopic Dermatitis Part 2. 特应性皮炎的创新和新兴疗法2。
IF 1.9 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2025-01-01 Epub Date: 2025-05-03 DOI: 10.1007/s40521-025-00389-w
Robyn Okereke, Eric Simpson

Purpose of review: The purpose of this review is to discuss the novel aspects of topical therapies used for the treatment of AD. We also discuss the lapses observed when comparing topical therapies. After the innovations regarding systemic therapies in AD were highlighted in a first review (part 1), this second component (part 2) will perceive the advances in topical therapies for AD.

Recent findings: Recent history has realized a prompt evolution in the options for topical therapy in AD. Novel, molecularly targeted topical therapies appear to address the drawbacks of traditional topical medicines.

Summary: The transformation towards targeted AD therapies is associated with increased efficacy and safety profiles, as well as patient compliance. We also evaluate available real-world and long-term data. Future studies should focus on optimizing topical therapies by increasing the duration of available long-term data.

综述目的：本综述的目的是讨论用于治疗AD的局部疗法的新方面。我们还讨论了在比较局部治疗时观察到的失误。在第一篇综述（第1部分）中强调了阿尔茨海默病全身治疗的创新之后，第二部分（第2部分）将了解阿尔茨海默病局部治疗的进展。最近的发现：最近的历史已经实现了局部治疗的AD的选择迅速演变。新颖的分子靶向局部治疗似乎解决了传统局部药物的缺点。摘要：向靶向性阿尔茨海默病治疗的转变与提高疗效和安全性以及患者依从性有关。我们还评估可用的真实世界和长期数据。未来的研究应侧重于通过增加可获得的长期数据的持续时间来优化局部治疗。
{"title":"Innovations and Emerging Therapies in Atopic Dermatitis Part 2.","authors":"Robyn Okereke, Eric Simpson","doi":"10.1007/s40521-025-00389-w","DOIUrl":"10.1007/s40521-025-00389-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose of this review is to discuss the novel aspects of topical therapies used for the treatment of AD. We also discuss the lapses observed when comparing topical therapies. After the innovations regarding systemic therapies in AD were highlighted in a first review (part 1), this second component (part 2) will perceive the advances in topical therapies for AD.</p><p><strong>Recent findings: </strong>Recent history has realized a prompt evolution in the options for topical therapy in AD. Novel, molecularly targeted topical therapies appear to address the drawbacks of traditional topical medicines.</p><p><strong>Summary: </strong>The transformation towards targeted AD therapies is associated with increased efficacy and safety profiles, as well as patient compliance. We also evaluate available real-world and long-term data. Future studies should focus on optimizing topical therapies by increasing the duration of available long-term data.</p>","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"12 ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allergic Contact Dermatitis in Children: Clinical Management and Emerging Allergens 儿童过敏性接触性皮炎：临床管理和新出现的过敏原
IF 1.1 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2024-01-10 DOI: 10.1007/s40521-023-00357-2
Sebastian Vigand Svendsen, Kristian F. Mose, C. Mortz
{"title":"Allergic Contact Dermatitis in Children: Clinical Management and Emerging Allergens","authors":"Sebastian Vigand Svendsen, Kristian F. Mose, C. Mortz","doi":"10.1007/s40521-023-00357-2","DOIUrl":"https://doi.org/10.1007/s40521-023-00357-2","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"77 14","pages":"1-15"},"PeriodicalIF":1.1,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139440762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Bacteria to Host: Deciphering the Impact of Sphingolipid Metabolism on Food Allergic Reactions 从细菌到宿主解读鞘脂代谢对食物过敏反应的影响
IF 1.1 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-12-26 DOI: 10.1007/s40521-023-00356-3
E. Zubeldia-Varela, Andrea Macías-Camero, M. Pérez-Gordo
{"title":"From Bacteria to Host: Deciphering the Impact of Sphingolipid Metabolism on Food Allergic Reactions","authors":"E. Zubeldia-Varela, Andrea Macías-Camero, M. Pérez-Gordo","doi":"10.1007/s40521-023-00356-3","DOIUrl":"https://doi.org/10.1007/s40521-023-00356-3","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"33 2","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139155756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is New in Alpha-Gal Syndrome? 阿尔法-醛综合征的新进展是什么？
IF 1.1 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-11-22 DOI: 10.1007/s40521-023-00353-6
Teresa Peralta, Gigia Roizen, Natalia Crisóstomo, Raquel Aguilera-Insunza
{"title":"What is New in Alpha-Gal Syndrome?","authors":"Teresa Peralta, Gigia Roizen, Natalia Crisóstomo, Raquel Aguilera-Insunza","doi":"10.1007/s40521-023-00353-6","DOIUrl":"https://doi.org/10.1007/s40521-023-00353-6","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"5 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of Drug Allergy Alert Systems: Present and Future 药物过敏警报系统的实用性：现状与未来
IF 1.1 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-11-18 DOI: 10.1007/s40521-023-00351-8
P. Quan, Sergio Sánchez-Fernández, Lucía Parrado Gil, Alfonso Calvo Alonso, José Miguel Bodero Sánchez, Ana Ortega Eslava, Marta Luri, Gabriel Gastaminza Lasarte
{"title":"Usefulness of Drug Allergy Alert Systems: Present and Future","authors":"P. Quan, Sergio Sánchez-Fernández, Lucía Parrado Gil, Alfonso Calvo Alonso, José Miguel Bodero Sánchez, Ana Ortega Eslava, Marta Luri, Gabriel Gastaminza Lasarte","doi":"10.1007/s40521-023-00351-8","DOIUrl":"https://doi.org/10.1007/s40521-023-00351-8","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"57 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139261694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tree-Pollen-Related Food Allergies: Birch Pollen and More 与树木花粉相关的食物过敏症：桦树花粉及其他
IF 1.1 Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-11-16 DOI: 10.1007/s40521-023-00352-7
E. Scala, Alessandro Maria Marra, Valeria Villella, G. Celi, Riccardo Asero
{"title":"Tree-Pollen-Related Food Allergies: Birch Pollen and More","authors":"E. Scala, Alessandro Maria Marra, Valeria Villella, G. Celi, Riccardo Asero","doi":"10.1007/s40521-023-00352-7","DOIUrl":"https://doi.org/10.1007/s40521-023-00352-7","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"114 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139267102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe Asthma Patients: Can We Really Wean Them off of Oral Corticosteroids 严重哮喘患者:我们真的能让他们戒掉口服皮质类固醇吗
Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-10-11 DOI: 10.1007/s40521-023-00340-x
Cesar Fireth Pozo-Beltran, Barbara Elizondo-Villarreal, Fernando Morett-Vera, Victor Gonzalez-Uribe, Roxana Minerva Rodriguez-Romo, Elsy Maureen Navarrete-Rodriguez, Jorge Andres Paniagua-Santos, Jesus Fernando Ledezma-Ortega, Adriana Virginia Briceño-Gamboa
{"title":"Severe Asthma Patients: Can We Really Wean Them off of Oral Corticosteroids","authors":"Cesar Fireth Pozo-Beltran, Barbara Elizondo-Villarreal, Fernando Morett-Vera, Victor Gonzalez-Uribe, Roxana Minerva Rodriguez-Romo, Elsy Maureen Navarrete-Rodriguez, Jorge Andres Paniagua-Santos, Jesus Fernando Ledezma-Ortega, Adriana Virginia Briceño-Gamboa","doi":"10.1007/s40521-023-00340-x","DOIUrl":"https://doi.org/10.1007/s40521-023-00340-x","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136209281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiome in Atopic Dermatitis: Is It All About Staphylococcus aureus? 特应性皮炎的微生物群:是否全与金黄色葡萄球菌有关?
Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-09-29 DOI: 10.1007/s40521-023-00350-9
Cristina Gomez-Casado, Zsofia Unger, Peter Olah, Bernhard Homey
{"title":"Microbiome in Atopic Dermatitis: Is It All About Staphylococcus aureus?","authors":"Cristina Gomez-Casado, Zsofia Unger, Peter Olah, Bernhard Homey","doi":"10.1007/s40521-023-00350-9","DOIUrl":"https://doi.org/10.1007/s40521-023-00350-9","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135200233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Roots and Growth of Allergen Immunotherapy 过敏原免疫治疗的根源和发展
Q3 ALLERGY
Current Treatment Options in Allergy
Pub Date : 2023-09-28 DOI: 10.1007/s40521-023-00348-3
Ira Finegold
{"title":"The Roots and Growth of Allergen Immunotherapy","authors":"Ira Finegold","doi":"10.1007/s40521-023-00348-3","DOIUrl":"https://doi.org/10.1007/s40521-023-00348-3","url":null,"abstract":"","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135387142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Current Treatment Options in Allergy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1