Pub Date : 2022-03-31DOI: 10.47363/jghr/2022(3)129
Y. Sreenija, D. Dutta
A 56 year old gentleman with no known comorbidities presented with pain abdomen for 1 month. Triphasic CECT abdomen showed features of cirrhosis with surface irregularities, fissural widening and volume redistribution changes in the liver. Segment VII of liver showed an arterial enhancing lesion measuring 4.2 x 3.5cm showing washout in delayed phase. In view of BCLC A stage with Child Pugh B7, ablation was planned. Before proceeding with ablation, in view of very high alpha-fetoprotein (AFP) level of 9836 ng/mL, he was advised for metastatic evaluation with 18F-FDG PET-CT. The PET scan showed abnormal heterogeneous increased FDG uptake in segment VII of liver (SUV Max 4.7) with arterial enhancement and washout suggestive of metabolically active hepatocellular carcinoma. Also seen was an abnormal linear increased FDG uptake in right branch of portal vein (SUV Max 4.8) which was suggestive of portal vein invasion. In view of portal vein tumor thrombus, ablation procedure was deferred for the patient. Role of PET scan in HCC with vascular invasion is not yet defined. Poor specificity of FDG PET is the major hindrance in establishing PET scan as diagnostic tool for vascular invasion. In small segment invasion when CECT is not able to differentiate between tumour versus bland thrombus PET scan may be significant tool to differentiate between bland thrombus and tumour thrombus. Vascular invasion confirmation have treatment related and prognostic significance. There is a need for a prospective study evaluating the prognostic significance of PET scan based diagnosis of vascular invasion.
56岁男性，无已知合并症，腹痛1个月。腹部三相CECT表现为肝硬化，肝表面不规则，肝裂增宽，体积再分布改变。肝脏第七节段显示4.2 x 3.5cm的动脉增强病变，呈延迟期冲洗。鉴于BCLC A期伴Child Pugh B7，计划行消融治疗。在继续消融之前，考虑到非常高的甲胎蛋白(AFP)水平9836 ng/mL，建议用18F-FDG PET-CT评估转移性。PET扫描显示肝脏第七段FDG摄取异常异质增加(SUV Max 4.7)，动脉增强和冲洗提示代谢活跃的肝细胞癌。门静脉右支FDG摄取异常线性增加(SUV Max 4.8)，提示门静脉侵犯。考虑到门静脉肿瘤血栓，患者延期行消融手术。PET扫描在肝细胞癌伴血管侵犯中的作用尚未明确。FDG PET特异性差是阻碍PET扫描作为血管侵犯诊断工具的主要障碍。在小段侵犯时，当CECT不能区分肿瘤和无症状血栓时，PET扫描可能是区分无症状血栓和肿瘤血栓的重要工具。血管侵犯的确认对治疗和预后有重要意义。有必要进行一项前瞻性研究，评估基于PET扫描诊断血管侵犯的预后意义。
{"title":"Role of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Detection of Portal Vein Tumor Thrombosis in Hepatocellular Carcinoma","authors":"Y. Sreenija, D. Dutta","doi":"10.47363/jghr/2022(3)129","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)129","url":null,"abstract":"A 56 year old gentleman with no known comorbidities presented with pain abdomen for 1 month. Triphasic CECT abdomen showed features of cirrhosis with surface irregularities, fissural widening and volume redistribution changes in the liver. Segment VII of liver showed an arterial enhancing lesion measuring 4.2 x 3.5cm showing washout in delayed phase. In view of BCLC A stage with Child Pugh B7, ablation was planned. Before proceeding with ablation, in view of very high alpha-fetoprotein (AFP) level of 9836 ng/mL, he was advised for metastatic evaluation with 18F-FDG PET-CT. The PET scan showed abnormal heterogeneous increased FDG uptake in segment VII of liver (SUV Max 4.7) with arterial enhancement and washout suggestive of metabolically active hepatocellular carcinoma. Also seen was an abnormal linear increased FDG uptake in right branch of portal vein (SUV Max 4.8) which was suggestive of portal vein invasion. In view of portal vein tumor thrombus, ablation procedure was deferred for the patient. Role of PET scan in HCC with vascular invasion is not yet defined. Poor specificity of FDG PET is the major hindrance in establishing PET scan as diagnostic tool for vascular invasion. In small segment invasion when CECT is not able to differentiate between tumour versus bland thrombus PET scan may be significant tool to differentiate between bland thrombus and tumour thrombus. Vascular invasion confirmation have treatment related and prognostic significance. There is a need for a prospective study evaluating the prognostic significance of PET scan based diagnosis of vascular invasion.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115484885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.47363/jghr/2022(3)128
A. Mohammed, A. Bane
Acquired hepato-cerebral degeneration (AHD) is a neurologic syndrome caused by liver dysfunction and long-standing portosystemic shunting. There is scarce and conflicting information regarding the clinical course of AHD. We report the case of a 25-year-old male who underwent splenectomy and splenorenal shunt for recurrent UGIB 20 to Esophageal varices 20 to Non-Cirrhotic portal hypertension 20 to Non-Cirrhotic portal fibrosis and hypersplenism, in Mumbai, India. He presented with slow movement, hypophonia, gait instability, and rigidity of the lower extremities. In this paper, we discuss the patient’s case with literature review.
{"title":"A Case of Acquired Hepato-Cerebral Degeneration after Splenorenal Shunt from Ethiopia","authors":"A. Mohammed, A. Bane","doi":"10.47363/jghr/2022(3)128","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)128","url":null,"abstract":"Acquired hepato-cerebral degeneration (AHD) is a neurologic syndrome caused by liver dysfunction and long-standing portosystemic shunting. There is scarce and conflicting information regarding the clinical course of AHD. We report the case of a 25-year-old male who underwent splenectomy and splenorenal shunt for recurrent UGIB 20 to Esophageal varices 20 to Non-Cirrhotic portal hypertension 20 to Non-Cirrhotic portal fibrosis and hypersplenism, in Mumbai, India. He presented with slow movement, hypophonia, gait instability, and rigidity of the lower extremities. In this paper, we discuss the patient’s case with literature review.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129358815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Diabetes mellitus (DM) and Hepatitis C Virus (HCV) infections are a global major public health threat. Their co-infections and associated risk factors have been postulated in many countries, unfortunately, no such data exist in Cameroon. This study aims to determine the prevalence and possible predictors of HCV among DM patients. Methods: We conducted a cross-sectional study among DM patients at Regional Hospital Bamenda from February to June 2020. Blood samples were collected and tested for the presence of HCV. Data were analyzed using SPSS version 23. Results: The study comprised 193 participants. The mean (Std. error) age and random blood sugar level of the participants were 46.12(0.9) years and 134.15(4.07) g/dl respectively. HCV prevalence was 3.11% (6). The distribution of HCV infection did not show any significant difference with social demographic factors (p > 0.05). Similarly, HCV was insignificantly (p > 0.05) higher in patients with T2DM 6(3.4%), those with disease duration >5 years 4(4.4%), and those receiving injectable drugs 2(9.1%). Possible predictors (p<0.05) of HCV identified in this study include; uncontrolled diabetes (7.4%), family history of diabetes (19.2%), hepatitis 2(15.4%), alcohol intake (7.6%), multiple sex partners (6.5%), sharing sharp objects (9.1%), those with Tattoos (9.4%), scarification marks (3.6%), as well as those who have been hospitalized (6.7%), or received blood transfusion (25.0%) at least once. Conclusion: HCV testing and linkage to care among DM patients should be made imperative in order to design effective treatment and prevention programs that will reduce the morbidity and mortality rates.
糖尿病(DM)和丙型肝炎病毒(HCV)感染是全球主要的公共卫生威胁。他们的共同感染和相关的危险因素在许多国家都是假定的，不幸的是，喀麦隆没有这样的数据。本研究旨在确定糖尿病患者中HCV的患病率和可能的预测因素。方法:我们于2020年2月至6月在巴门达地区医院对糖尿病患者进行了横断面研究。采集血样并检测丙型肝炎病毒的存在。数据分析采用SPSS version 23。结果:该研究包括193名参与者。参与者的平均(标准差)年龄和随机血糖水平分别为46.12(0.9)岁和134.15(4.07)g/dl。HCV患病率为3.11%(6)。HCV感染分布与社会人口统计学因素差异无统计学意义(p > 0.05)。同样，2型糖尿病患者(3.4%)、病程>5年4(4.4%)和接受注射药物2(9.1%)的HCV升高无统计学意义(p > 0.05)。本研究确定的HCV可能的预测因素(p<0.05)包括;未控制的糖尿病(7.4%)，糖尿病家族史(19.2%)，2型肝炎(15.4%)，酒精摄入(7.6%)，多个性伴侣(6.5%)，共用尖锐物品(9.1%)，有纹身(9.4%)，划痕(3.6%)，以及住院(6.7%)或至少接受过一次输血(25.0%)的人。结论:为了设计有效的治疗和预防方案，降低发病率和死亡率，应在糖尿病患者中进行HCV检测并与护理联系起来。
{"title":"Incidence of Hepatitis C Virus infection and the potential predictors among patients with diabetes mellitus in the Bamenda Regional Hospital in Cameroon","authors":"Lem Edith Abongwa, Ntoh Bazil Kuh, Kubong Rene Ndenge","doi":"10.47363/jghr/2022(3)130","DOIUrl":"https://doi.org/10.47363/jghr/2022(3)130","url":null,"abstract":"Introduction: Diabetes mellitus (DM) and Hepatitis C Virus (HCV) infections are a global major public health threat. Their co-infections and associated risk factors have been postulated in many countries, unfortunately, no such data exist in Cameroon. This study aims to determine the prevalence and possible predictors of HCV among DM patients. Methods: We conducted a cross-sectional study among DM patients at Regional Hospital Bamenda from February to June 2020. Blood samples were collected and tested for the presence of HCV. Data were analyzed using SPSS version 23. Results: The study comprised 193 participants. The mean (Std. error) age and random blood sugar level of the participants were 46.12(0.9) years and 134.15(4.07) g/dl respectively. HCV prevalence was 3.11% (6). The distribution of HCV infection did not show any significant difference with social demographic factors (p > 0.05). Similarly, HCV was insignificantly (p > 0.05) higher in patients with T2DM 6(3.4%), those with disease duration >5 years 4(4.4%), and those receiving injectable drugs 2(9.1%). Possible predictors (p<0.05) of HCV identified in this study include; uncontrolled diabetes (7.4%), family history of diabetes (19.2%), hepatitis 2(15.4%), alcohol intake (7.6%), multiple sex partners (6.5%), sharing sharp objects (9.1%), those with Tattoos (9.4%), scarification marks (3.6%), as well as those who have been hospitalized (6.7%), or received blood transfusion (25.0%) at least once. Conclusion: HCV testing and linkage to care among DM patients should be made imperative in order to design effective treatment and prevention programs that will reduce the morbidity and mortality rates.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127148105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.47363/jghr/2021(2)127
K. E., Leyna G
Background: Gastroesophageal reflux disease (GERD) is reported to occur in 10-20% of general population in Western countries and in about 5% in Asian countries. There is little data regarding its prevalence, pattern, associated factors and impact on the quality of life in African countries. The aim of this study was to determine the prevalence, pattern, quality of life and factors associated with GERD among outpatients in the city of Dar es Salaam in Tanzania. Methods: Between 01 June 2013 and 31 July 2013, a total of 1062 adults aged 18 years and above were recruited into this cross-sectional study and completed Swahili-language self-administered questionnaires. The Frequency Scale for the Symptoms of GERD questionnaire was used as a diagnostic tool for GERD and quality of life was assessed using the Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire. Results: The mean age ± standard deviation of the study participants was 46.0±19.5years and 60.5% were females. The prevalence of GERD was 31.5% and was higher among females compared to males (p = 0.001). The quality of life in patients with GERD was lower in all five domains of the QOLRAD questionnaire. About two thirds (59.7%) of patients with GERD had previously sought medical advice and 59.6% had used medications for their GERD symptoms. Conclusions: The prevalence of GERD was high in this patient population and was significantly higher among females compared to men. Participants with GERD demonstrated significant impairment in the quality of life.
{"title":"GERD is Common and Causes Significant Quality of Life Impairment: Results from Outpatients in Dar es Salaam, Tanzania","authors":"K. E., Leyna G","doi":"10.47363/jghr/2021(2)127","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)127","url":null,"abstract":"Background: Gastroesophageal reflux disease (GERD) is reported to occur in 10-20% of general population in Western countries and in about 5% in Asian countries. There is little data regarding its prevalence, pattern, associated factors and impact on the quality of life in African countries. The aim of this study was to determine the prevalence, pattern, quality of life and factors associated with GERD among outpatients in the city of Dar es Salaam in Tanzania. Methods: Between 01 June 2013 and 31 July 2013, a total of 1062 adults aged 18 years and above were recruited into this cross-sectional study and completed Swahili-language self-administered questionnaires. The Frequency Scale for the Symptoms of GERD questionnaire was used as a diagnostic tool for GERD and quality of life was assessed using the Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire. Results: The mean age ± standard deviation of the study participants was 46.0±19.5years and 60.5% were females. The prevalence of GERD was 31.5% and was higher among females compared to males (p = 0.001). The quality of life in patients with GERD was lower in all five domains of the QOLRAD questionnaire. About two thirds (59.7%) of patients with GERD had previously sought medical advice and 59.6% had used medications for their GERD symptoms. Conclusions: The prevalence of GERD was high in this patient population and was significantly higher among females compared to men. Participants with GERD demonstrated significant impairment in the quality of life.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130139921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.47363/jghr/2021(2)126
Hazim abdul rahman Alhiti
{"title":"Diabetic Gastroparesis: Please Help Me?","authors":"Hazim abdul rahman Alhiti","doi":"10.47363/jghr/2021(2)126","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)126","url":null,"abstract":"","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126510031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.47363/jghr/2021(2)124
Giovanna De Agostini Camargo, Antônia de Abreu Afrange, João Kleber de Almeida Gentile
The use of mechanical ventilation can be performed in situations where patients need ventilatory support to maintain adequate oxygenation. Its inappropriate use can cause some complications, among them: pneumothorax and pneumoperitoneum. Our report describes a 28-year-old man admitted to the ICU with a diagnosis of Covid-19 requiring mechanical ventilation with orotracheal intubation due to acute respiratory failure. During the patient’s clinical evolution he presented bilateral pneumothorax with evolution and progression to secondary pneumoperitoneum, where we sought to understand the relationship between the two conditions.
{"title":"Pneumoperitoneum Secondary to Pneumothorax Post-Intubation in a Patient with Difficult Airway","authors":"Giovanna De Agostini Camargo, Antônia de Abreu Afrange, João Kleber de Almeida Gentile","doi":"10.47363/jghr/2021(2)124","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)124","url":null,"abstract":"The use of mechanical ventilation can be performed in situations where patients need ventilatory support to maintain adequate oxygenation. Its inappropriate use can cause some complications, among them: pneumothorax and pneumoperitoneum. Our report describes a 28-year-old man admitted to the ICU with a diagnosis of Covid-19 requiring mechanical ventilation with orotracheal intubation due to acute respiratory failure. During the patient’s clinical evolution he presented bilateral pneumothorax with evolution and progression to secondary pneumoperitoneum, where we sought to understand the relationship between the two conditions.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121298067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.47363/jghr/2021(2)120
Alkhatib Amani, Hallal Marwa BS Biology
Background: Hepatitis B virus (HBV) is a major cause of the liver disease that could lead to acute and chronic inflammation of the liver. In this study we collected anti HBC antibodies (anti hepatitis B core) results done as screening of blood donors from three hospital centers in Lebanon between Jan.2016to Jan.2019. The aim of this study is to collect epidemiological data on the prevalence of positive anti HBC antibodies in blood donors of different nationalities. Method: Blood donation records from the three hospitals were collected from Jan. 2016 till Jan. 2019 and they included 16000 volunteers for blood donation and all these donors were tested for anti HBC antibodies. Results: The total number of donors was 16000, 1224 volunteers (7.65%) had positive anti HBC test. The prevalence of anti HBC antibodies was higher in Syrian population with a prevalence of 12.9% as compared to the Lebanese donors with prevalence of 6.6%. Age was found to have a statistically significant relationship with the prevalence of hepatitis B. blood group was found not to have a statistically significant relationship with hepatitis B.
{"title":"Prevalence of Anti HBC Antibodies in Blood Donors from Different Centers in Lebanon","authors":"Alkhatib Amani, Hallal Marwa BS Biology","doi":"10.47363/jghr/2021(2)120","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)120","url":null,"abstract":"Background: Hepatitis B virus (HBV) is a major cause of the liver disease that could lead to acute and chronic inflammation of the liver. In this study we collected anti HBC antibodies (anti hepatitis B core) results done as screening of blood donors from three hospital centers in Lebanon between Jan.2016to Jan.2019. The aim of this study is to collect epidemiological data on the prevalence of positive anti HBC antibodies in blood donors of different nationalities. Method: Blood donation records from the three hospitals were collected from Jan. 2016 till Jan. 2019 and they included 16000 volunteers for blood donation and all these donors were tested for anti HBC antibodies. Results: The total number of donors was 16000, 1224 volunteers (7.65%) had positive anti HBC test. The prevalence of anti HBC antibodies was higher in Syrian population with a prevalence of 12.9% as compared to the Lebanese donors with prevalence of 6.6%. Age was found to have a statistically significant relationship with the prevalence of hepatitis B. blood group was found not to have a statistically significant relationship with hepatitis B.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123642703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.47363/jghr/2021(2)121
A. M. Atiaallah, Mutaz Ogeal Osman
Esophageal Cancer is 6th common cause of cancer death worldwide, internationally the outcome of esophageal cancer is very poor. In Sudan esophageal cancer is also one of the most common malignancies and devastating disease with high mortality [1,3]. This study investigated esophageal cancer in the red sea state, east of Sudan over period October 2016 to October 2018, in port Sudan oncology center. The study included 40 patients, data was collected using a constructed structure pretest questionnaire, evaluated and compared with standard published literature. Objectives: The study was aimed to look at the epidemiology, risk Factors, clinical presentations and different management modalities of esophageal cancer in the red sea state, east of Sudan. Methods and Patients: This study was across sectional retro prospective study, centre based, and was conducted in Port Sudan Oncology Center in port Sudan, East of Sudan over period of two years from October 2016 to October 2018. Results: 40 patients involved in the study, This study was showed that the female were more affected with disease(65%), all patients in this study (100%) were taking coffee with ginger and pepper regularly in the early morning, and this is considered as the most important risk factor was known through this study, while the other risk factor their percentage as following; Hot tea (95%), GERD(42.5%), Smoking(10%) ,Alcohol consumption (2.5%).Dysphagia was the shared symptom between all the cases(100%), while the other symptoms came in different percentage. Conclusion: Esophageal Cancer was higher in female, more common in the age group 50_70 years old and is common in Beja tribe (50%). The most common risk factor is regular taking of coffee with ginger (100%). Unfortunately the mortality rate (52.5%) within 5-years after the diagnosis
{"title":"Epidemiology, Risk Factors and Management of Esophageal Cancer in East of Sudan (Single center experience from 2016-2018)","authors":"A. M. Atiaallah, Mutaz Ogeal Osman","doi":"10.47363/jghr/2021(2)121","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)121","url":null,"abstract":"Esophageal Cancer is 6th common cause of cancer death worldwide, internationally the outcome of esophageal cancer is very poor. In Sudan esophageal cancer is also one of the most common malignancies and devastating disease with high mortality [1,3]. This study investigated esophageal cancer in the red sea state, east of Sudan over period October 2016 to October 2018, in port Sudan oncology center. The study included 40 patients, data was collected using a constructed structure pretest questionnaire, evaluated and compared with standard published literature. Objectives: The study was aimed to look at the epidemiology, risk Factors, clinical presentations and different management modalities of esophageal cancer in the red sea state, east of Sudan. Methods and Patients: This study was across sectional retro prospective study, centre based, and was conducted in Port Sudan Oncology Center in port Sudan, East of Sudan over period of two years from October 2016 to October 2018. Results: 40 patients involved in the study, This study was showed that the female were more affected with disease(65%), all patients in this study (100%) were taking coffee with ginger and pepper regularly in the early morning, and this is considered as the most important risk factor was known through this study, while the other risk factor their percentage as following; Hot tea (95%), GERD(42.5%), Smoking(10%) ,Alcohol consumption (2.5%).Dysphagia was the shared symptom between all the cases(100%), while the other symptoms came in different percentage. Conclusion: Esophageal Cancer was higher in female, more common in the age group 50_70 years old and is common in Beja tribe (50%). The most common risk factor is regular taking of coffee with ginger (100%). Unfortunately the mortality rate (52.5%) within 5-years after the diagnosis","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132584181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.47363/jghr/2021(2)119
Yerimova NZh, Shirtayev Bk
{"title":"Modern View of the Problem of Antibiotic Resistance in Children before and after Liver Transplantation, Causes of Antibiotic Resistance","authors":"Yerimova NZh, Shirtayev Bk","doi":"10.47363/jghr/2021(2)119","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)119","url":null,"abstract":"","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131480204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.47363/jghr/2021(2)122
Mar Achalandabaso Boira, James Richards
Purpose: A major disruption of routine hospital services has occurred globally after SARS-CoV-2 pandemic. Current publications are based on large databases collected from hospitals with different characteristics which may not apply to all centres since the impact of SARS-CoV-2 varies depending on the incidence in each area. We studied the incidence of perioperative SARS-CoV-2 infection in surgical patients. Methods: We performed an observational, retrospective cohort study in patients undergoing surgery between March 16th to May 15th 2020. Results: Four patients (5.4%) tested positive with SARS-CoV-2, all positive results were obtained postoperatively. SARS-CoV-2 status was known at the time of surgery in 23 (60%) patients in emergency surgery and 20 patients (57%) in elective surgery. Mortality rate was 13% in emergency surgery with no cases due to SARS-CoV-2 related complications. Nine patients (25.7%) had changes in their management in elective surgery, no deaths were reported and one patient developed SARS-CoV-2 bilateral pneumonia. Discussion: Our results show that SARS-CoV-2 infection among surgical patients was low in our centre. Changes in policies on surgical activity during the SARS-CoV-2 pandemic should be taken at a regional or hospital level to reflect the local burden of SARS-CoV-2 and availability of resources.
{"title":"Should Local Rather than National Policy Determine our Approach to Surgery During SARS- CoV-2?","authors":"Mar Achalandabaso Boira, James Richards","doi":"10.47363/jghr/2021(2)122","DOIUrl":"https://doi.org/10.47363/jghr/2021(2)122","url":null,"abstract":"Purpose: A major disruption of routine hospital services has occurred globally after SARS-CoV-2 pandemic. Current publications are based on large databases collected from hospitals with different characteristics which may not apply to all centres since the impact of SARS-CoV-2 varies depending on the incidence in each area. We studied the incidence of perioperative SARS-CoV-2 infection in surgical patients. Methods: We performed an observational, retrospective cohort study in patients undergoing surgery between March 16th to May 15th 2020. Results: Four patients (5.4%) tested positive with SARS-CoV-2, all positive results were obtained postoperatively. SARS-CoV-2 status was known at the time of surgery in 23 (60%) patients in emergency surgery and 20 patients (57%) in elective surgery. Mortality rate was 13% in emergency surgery with no cases due to SARS-CoV-2 related complications. Nine patients (25.7%) had changes in their management in elective surgery, no deaths were reported and one patient developed SARS-CoV-2 bilateral pneumonia. Discussion: Our results show that SARS-CoV-2 infection among surgical patients was low in our centre. Changes in policies on surgical activity during the SARS-CoV-2 pandemic should be taken at a regional or hospital level to reflect the local burden of SARS-CoV-2 and availability of resources.","PeriodicalId":363979,"journal":{"name":"Journal of Gastroenterology & Hepatology Reports","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126640002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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