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Umbilical catheter rupture: A serious complication in neonatal intensive care units 脐管破裂:新生儿重症监护病房的一个严重并发症
Q2 Medicine Pub Date : 2021-09-01 DOI: 10.1016/j.ijpam.2020.09.002
Wasim Khasawneh , Dua N. Samara , Ziad A. Bataineh

Umbilical catheterization is commonly used as a route to provide medications and fluids to the neonates as well as for blood sampling and continuous monitoring. Although the rupture of umbilical catheters is considered as a rare, preventable complication, it has been reported several times in the literature. Healthcare providers need to be cautious with catheter placement, maintenance, and removal to prevent such a complication.

Hereby, we review the literature about this complication after presenting two incidents of umbilical venous catheter rupture in two separate patients in our neonatal ICU. One was removed easily through the umbilical stump, whereas the other required surgical exploration.

脐带导尿通常用于向新生儿提供药物和液体以及血液采样和持续监测。虽然脐带导管破裂被认为是一种罕见的、可预防的并发症,但在文献中已多次报道。医疗保健提供者需要小心导管的放置、维护和移除,以防止此类并发症的发生。在此,我们回顾了在我们新生儿ICU的两个独立的患者中发生的两起脐静脉导管破裂事件后关于这一并发症的文献。其中一个很容易通过脐带残端切除,而另一个则需要手术探查。
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引用次数: 4
Influence of tension of the nuchal cord to the developmental output in a one-year-old child 颈索张力对一岁儿童发育输出的影响
Q2 Medicine Pub Date : 2021-09-01 DOI: 10.1016/j.ijpam.2020.04.003
Edina Karabeg , Enes Karabeg , Adi Karabeg

Objective

Influence of nuchal umbilical cord tension in a newborn on the developmental outcome at the end of the first year.

Methods

and subjects of research: The research is prospective, conducted in northern Bosnia and Herzegovina (Una Sana Canton), for a period of five years. In the research study, we included newborns with a nuchal cord (tight and loose) and newborns without a nuchal cord (control group). We were tracking and recording the Apgar score and the conventional cardiotocography (CTG) findings in both groups. The development of newborns was monitored by the Munich Functional Scale and the development was evaluated at the end of the first year of life.

Results

Statistically, there was a significant presence (P< .001) of Apgar score lower than 7 in newborns with nuchal cord concerning the control group. There were significantly lower Apgar score findings in newborns with a tight nuchal cord compared to ones with a loose nuchal cord (P<.001). Pathological cardiotocographic findings were monitored and the statistical significance in neonates with a nuchal cord concerning the control group. Cardiotocographic data in a neonatal group with tight nuchal cord were statistically significantly lower concerning cardiotocographic data in neonates with a loose nuchal cord (P<.001). Infants at the age of 1 year born with tight nuchal cord were found to have a significant developmental delay compared to those born with loose nuchal cord and control group (P<.001).

Conclusion

The nuchal cord is the risk factor for later developmental deviation. Early diagnosis of the nuchal cord, especially tight cord around the neck (nuchal cord), is important for the prevention of later morbidity.

目的探讨新生儿颈脐带张力对一年末发育结局的影响。研究方法和主题:研究是前瞻性的,在波斯尼亚和黑塞哥维那北部(Una Sana Canton)进行,为期五年。在本研究中,我们包括有颈带(紧或松)和没有颈带的新生儿(对照组)。我们跟踪并记录两组患者的Apgar评分和常规心脏造影(CTG)结果。通过慕尼黑功能量表监测新生儿的发育,并在一岁结束时对其进行评估。结果统计学上,有显著的存在(P<颈带新生儿Apgar评分低于7分与对照组比较差异有统计学意义(0.001)。颈带紧的新生儿的Apgar评分明显低于颈带松的新生儿(P<.001)。监测新生儿颈髓带的病理心动图结果,并与对照组比较有统计学意义。颈索较紧新生儿组的心电图数据与颈索较松新生儿组的心电图数据比较,差异有统计学意义(p < 0.01)。1岁出生时颈索紧的婴儿与出生时颈索松的婴儿和对照组相比有显著的发育迟缓(P<.001)。结论颈髓是日后发育偏离的危险因素。颈索的早期诊断,特别是颈索周围的紧绷(颈索),对于预防后期发病是很重要的。
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引用次数: 0
Breastfeeding preterm born infant: Chance and challenge 母乳喂养早产婴儿:机遇与挑战
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.02.003
Svetlana Zukova , Valda Krumina , Jelena Buceniece

Background and Objectives

For preterm infants, breastmilk plays an important role in their development, but mothers encounter a number of barriers to breastfeeding. The aim of this study was to investigate breastfeeding prevalence in preterm infants and to examine factors that may face mothers when starting to feed at-breast and their impact on the result.

Methods

Women (N = 79) with preterm infants (N = 84) were interviewed within the follow-up program in Latvia during a six-month period in 2018 using the original study protocol.

Results

61.9% infants were breastfed and 38.1% were not. The median infant birth weight in breastfed group was 1730 g, the median duration of tube feeding 21 days. The median age when started to feed at-breast 33 days. Later only 40.4% infants were still feeding at-breast. A relationship was found between breastfeeding and the mother’s confidence during pregnancy that she would breastfeed (P < .05). 98% mothers who began to feed at-breast, during pregnancy were confident that they would breastfeed. 54.2% women who started to breastfeed as success mentioned medical staff training, 29.2% family support.

The median birth weight in the non-breastfed group was 1494 g, the median duration of tube feeding 21 days. 50% women who did not begin to breastfeed had not received enough information about breastfeeding; 17.2% during pregnancy were not confident that they would breastfeed. 38.7% women stated infants’ inability to suckle as failure, 22.6% thought they had no milk. Mothers under 32 years were more likely not to breastfeed their infant (OR = 0.8, 95% CI 0.33–1.96).

Conclusion

Most mothers began to breastfeed immediately, less than half continued later. Women did not receive enough family support. Young maternal age was associated with decrease in breastfeeding. Mothers with higher education were more likely to breastfeed. Being born extremely preterm and very preterm were associated with the least chance of being breastfed.

背景和目的对于早产儿来说,母乳在他们的发育中起着重要的作用,但母亲们在母乳喂养方面遇到了许多障碍。本研究的目的是调查早产婴儿母乳喂养的流行程度,并检查母亲开始母乳喂养时可能面临的因素及其对结果的影响。方法采用原始研究方案,在2018年6个月的随访计划中对拉脱维亚早产儿(N = 84)的妇女(N = 79)进行访谈。结果61.9%的婴儿接受母乳喂养,38.1%未接受母乳喂养。母乳喂养组婴儿出生体重中位数为1730 g,管饲时间中位数为21 d。开始母乳喂养的中位年龄为33天。后来,只有40.4%的婴儿仍在母乳喂养。发现母乳喂养与母亲在怀孕期间对母乳喂养的信心之间存在关系(P <. 05)。98%在怀孕期间开始母乳喂养的母亲有信心自己会母乳喂养。成功开始母乳喂养的妇女中有54.2%提到医务人员培训,29.2%提到家庭支持。非母乳喂养组出生体重中位数为1494 g,管饲时间中位数为21 d。50%未开始母乳喂养的妇女没有获得足够的母乳喂养信息;17.2%的孕妇对母乳喂养没有信心。38.7%的女性认为婴儿不能吃奶是失败,22.6%的女性认为她们没有奶。32岁以下的母亲更有可能不母乳喂养婴儿(OR = 0.8, 95% CI 0.33-1.96)。结论大多数母亲立即开始母乳喂养,只有不到一半的母亲继续母乳喂养。妇女没有得到足够的家庭支持。年轻的母亲年龄与母乳喂养减少有关。受过高等教育的母亲更有可能母乳喂养。极度早产和非常早产的婴儿接受母乳喂养的几率最低。
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引用次数: 11
Diagnosis and management of community-acquired urinary tract infection in infants and children: Clinical guidelines endorsed by the Saudi Pediatric Infectious Diseases Society (SPIDS) 婴幼儿社区获得性尿路感染的诊断和管理:沙特儿科传染病学会(SPIDS)认可的临床指南
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2021.03.001
May Albarrak , Omar Alzomor , Rana Almaghrabi , Sarah Alsubaie , Faisal Alghamdi , Asrar Bajouda , Maha Nojoom , Hassan Faqeehi , Subhy Abo Rubeea , Razan Alnafeesah , Saeed Dolgum , Mohammed ALghoshimi , Sami AlHajjar , Dayel AlShahrani

Urinary tract infection (UTI) is the most common bacterial disease in childhood worldwide and may have significant adverse consequences, particularly for young children. In this guideline, we provide the most up-to-date information for the diagnosis and management of community-acquired UTI in infants and children aged over 90 days up to 14 years. The current recommendations given by the American Academy of Pediatrics Practice guidelines, Canadian Pediatric Society guideline, and other international guidelines are considered as well as regional variations in susceptibility patterns and resources. This guideline covers the diagnosis, therapeutic options, and prophylaxis for the management of community-acquired UTI in children guided by our local antimicrobial resistance pattern of the most frequent urinary pathogens. Neonates, infants younger than three months, immunocompromised patients, children recurrent UTIs, or renal abnormalities should be managed individually because these patients may require more extensive investigation and more aggressive therapy and follow up, so it is considered out of the scope of these guidelines. Establishment of children-specific guidelines for the diagnosis and management of community-acquired UTI can reduce morbidity and mortality. We present a clinical statement from the Saudi Pediatric Infectious Diseases Society (SPIDS), which concerns the diagnosis and management of community-acquired UTI in children.

尿路感染(UTI)是全世界儿童最常见的细菌性疾病,可能会产生严重的不良后果,特别是对幼儿。在本指南中,我们为90天以上至14岁婴幼儿社区获得性尿路感染的诊断和管理提供了最新的信息。目前美国儿科学会实践指南、加拿大儿科学会指南和其他国际指南给出的建议以及易感模式和资源的区域差异都被考虑在内。本指南涵盖了社区获得性儿童尿路感染的诊断、治疗方案和预防管理,以我们当地最常见的尿路病原体的抗微生物药物耐药性模式为指导。新生儿、3个月以下的婴儿、免疫功能低下患者、儿童复发性尿路感染或肾脏异常应单独处理,因为这些患者可能需要更广泛的调查和更积极的治疗和随访,因此被认为超出了本指南的范围。建立针对儿童的社区获得性尿路感染诊断和管理指南可以降低发病率和死亡率。我们提出了一份来自沙特儿童传染病学会(SPIDS)的临床声明,该声明涉及儿童社区获得性尿路感染的诊断和管理。
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引用次数: 6
Managing the ambiguity of the trainee and the trainer 管理学员和培训师之间的歧义
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.01.005
Muhammad Nauman Qureshi, Taimur Butt

The “trainee in difficulty” (TID) can have multiple causative factors which can impact the delivery of an expected standard of skill sets. The communication and interpersonal skills in Emergency Department (ED) setting are key to any trainee’s performance in an ED environment where team playing is a major factor in achieving safe and holistic care for patients. Trainer or a young faculty member responsible for the training may not have the emotional intelligence or experience to deal with all the issues faced by the TID. This paper talks about the difficulties faced by an experienced trainee in difficulty, who has changed his career from an experienced ED nurse to a trainee registrar in Emergency Medicine. The second case study is about a young emergency medicine residency program director who fails to appropriately address a trainee’s situation and compounds the trainees’ issues. The effect of honest, transparent communication of an educational supervisor and setting clear goals for the TID can have a huge impact on trainees’ performance. A residency program director’s inexperience and poor skills to deal and escalate the trainee’s issues may jeopardize a young physicians’ career.

“困难学员”(TID)可能有多种原因,这些因素可能会影响预期技能标准的交付。在急诊科(ED)环境中,团队合作是为患者提供安全和全面护理的主要因素,因此,沟通和人际交往技巧是任何实习生在急诊科环境中表现的关键。培训师或负责培训的年轻教员可能没有足够的情商或经验来处理工贸署面临的所有问题。本文讲述了一名经验丰富的急诊科实习护士从一名经验丰富的急诊科实习护士转变为一名见习急诊科注册护士所面临的困难。第二个案例研究是关于一个年轻的急诊医学住院医师项目主任,他没有恰当地处理实习生的情况,并使实习生的问题复杂化。教育督导诚实、透明的沟通,以及为工贸署设定明确的目标,对学员的表现有很大的影响。住院医师项目主任在处理和升级实习生问题方面缺乏经验和技能,可能会危及年轻医生的职业生涯。
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引用次数: 0
Incidental finding of a needle in the root of the mesentery of an 11-month-old boy: A case report 偶然发现一根针在肠系膜的根一个11个月大的男孩:一个病例报告
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.03.011
Dana Kalagi , Lama AlFakhri , Mays AlTahhan , Ayman AlKhamisy , Zakaria Habib , Wajeeh AlDekhail

Foreign body (FB) ingestion is very common in the pediatric population. Children will have different presentations based on their age, size, type, and site of the ingested FB. Some children can present with serious complications, others can be completely asymptomatic.

An eleven-month-old male child, previously healthy, was following up with the family medicine department for a routine visit. A pelvic x-ray was done to rule out developmental dysplasia of the hip, and a needle was found incidentally in the small bowel loops. The child was completely asymptomatic. Daily radiographs were taken three days in a row and showed that the needle was still in place. The patient was then referred to the pediatric surgery department for laparoscopic exploration and removal of the needle before complications occur. During exploration, the needle was found at the root of the mesentery. The needle was taken out uneventfully without the evidence of perforation.

It is unusual to find a sharp FB located at the root of the mesentery in a completely asymptomatic infant as an incidental finding. Serial radiographic images after the initial presentation of foreign body ingestion is important to guide us through surgical intervention.

异物(FB)摄入在儿科人群中非常常见。儿童会根据他们的年龄、大小、类型和摄入FB的部位有不同的表现。有些儿童会出现严重的并发症,有些则完全没有症状。一个11个月大的男婴,之前健康,在家庭医学部门进行了例行访问。骨盆x光检查排除了髋关节发育不良的可能性,并且在小肠袢中偶然发现了一根针。这孩子完全没有症状。连续三天每天拍x光片,显示针头仍在原位。然后,患者被转到儿科外科进行腹腔镜探查并在并发症发生之前取出针头。在探查过程中,在肠系膜的根部发现了针。针被顺利取出,没有穿孔的迹象。在完全无症状的婴儿中发现位于肠系膜根部的尖锐FB是不寻常的,这是一个偶然发现。首次出现异物摄入后的连续x线图像对指导我们进行手术治疗非常重要。
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引用次数: 0
Prevalence and special clinical and biochemical characteristics of familial type 1 (insulin dependent) diabetes mellitus in pediatric patients in a tertiary care setting 家族性1型(胰岛素依赖)糖尿病在三级医疗机构儿科患者中的患病率和特殊的临床生化特征
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.11.006
Angham AlMutair , Norah AlSabty , Hala AlNuaim , Rawan Al Hamdan , Afaf Moukaddem

Background and Objectives

The hereditable nature of type 1 diabetes mellitus (T1DM) makes it a condition that is in some cases shared among siblings. Studies that focus on the epidemiology of T1DM among siblings are scarce. The primary focus of the study is to estimate the prevalence of familial T1DM among siblings and the secondary focus is to identify the presence of any special clinical or biochemical characteristics specific to this entity.

Methods

In a retrospective cross-sectional study, the charts of 308 children (>1 year) diagnosed with type 1 diabetes mellitus in a Saudi tertiary care setting were reviewed. The patients who have one sibling or more with T1DM were included. The prevalence of familial T1DM among siblings was calculated, and specific clinical and biochemical characteristics were investigated. Data were analyzed using Statistical Package for the Social Sciences software version 22 (IBM SPSS Statistics for Windows). The control group includes all patients with type I DM who were excluded for sibling with DM.

Results

The prevalence of familial T1DM among siblings was estimated at 15.9%. Seventy-four percent of the patients with a positive family history of diabetes mellitus had one affected sibling only. The clinical presentation showed no significant differences relative to the age of presentation, gender, parental consanguinity, diabetic ketoacidosis at presentation, and its number of episodes. For the biochemical characteristics, autoantibody tests revealed no statistically significant difference, but the mean initial HbA1c levels were lower in patients who had diabetic siblings.

Conclusion

The prevalence of familial T1DM was found to be higher than that reported in other studies. No specific clinical or biochemical features were found to characterize familial T1DM among siblings.

背景与目的1型糖尿病(T1DM)的遗传性使其在某些情况下是兄弟姐妹共有的。关注兄弟姐妹间T1DM流行病学的研究很少。该研究的主要重点是估计家族性T1DM在兄弟姐妹中的患病率,次要重点是确定该实体特有的任何特殊临床或生化特征的存在。方法回顾性分析在沙特三级医疗机构诊断为1型糖尿病的308例儿童(1岁)的病历。其中包括有一个或多个兄弟姐妹患有T1DM的患者。计算家族性T1DM在兄弟姐妹中的患病率,并调查具体的临床和生化特征。数据分析使用Statistical Package for Social Sciences软件版本22 (IBM SPSS Statistics for Windows)。对照组包括所有排除兄弟姐妹患有糖尿病的1型糖尿病患者。结果家族性T1DM在兄弟姐妹中的患病率估计为15.9%。74%的糖尿病家族史阳性患者只有一个兄弟姐妹患病。临床表现与发病年龄、性别、亲缘关系、发病时糖尿病酮症酸中毒及其发作次数无显著差异。对于生化特征,自身抗体测试显示无统计学差异,但有糖尿病兄弟姐妹的患者平均初始HbA1c水平较低。结论家族性T1DM患病率高于其他研究报道。没有发现家族性T1DM在兄弟姐妹中的具体临床或生化特征。
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引用次数: 2
Breaking bad news to children with chronic kidney disease: A questionnaire-based study and literature review 慢性肾病儿童的坏消息:一项基于问卷的研究和文献综述
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.03.002
Weiam Almaiman , Areej Alfattani , Turki A. Alshareef

Introduction

Breaking bad news to caregivers of children with (CKD) [I can’t comment in the box] Title says to breaking bad news to children but in here, breaking bad news to caregivers. Please clarify and edit accordingly. is an important role of nephrologists. In our practice there has been a thought about parental dissatisfaction from breaking bad news to CKD patients. Caregiver’s preferences on how to be told the bad news in CKD children has not been studied adequately. Our objective was to identify how much is the emotional and knowledge satisfaction of CKD caregivers and the relation of their socioeconomic and educational levels with their preferences in breaking bad news.

Methods

A questionnaire based study was conducted for caregivers of CKD children, in the outpatient clinics, and peritoneal dialysis and hemodialysis units at the King Faisal Specialist Hospital and Research Centre for three months.

Results

83 questionnaires from caregivers of CKD patients age (1–14) years, mean age of 8.5 ± 3.9 years. (47.6%) were emotionally very satisfied, 29.5% were very satisfied about the knowledge they had.

Conclusion

Caregivers of CKD patients are satisfied emotionally more than the satisfaction about the amount of information they got. Different demographic data might affect their preferences in the way of receiving the bad news. The dissatisfaction suggesting that physicians’ communication skills needs improvement.

给CKD儿童看护人的坏消息[我不能在框里评论]标题是给孩子的坏消息,但在这里,给看护人的坏消息。请澄清并进行相应的编辑。是肾内科医生的重要角色。在我们的实践中,有一种想法是父母对CKD患者的坏消息感到不满。照顾者对如何告知CKD儿童坏消息的偏好尚未得到充分研究。我们的目的是确定CKD护理人员的情感和知识满意度,以及他们的社会经济和教育水平与他们在透露坏消息方面的偏好之间的关系。方法对费萨尔国王专科医院和研究中心的CKD儿童护理人员、门诊诊所、腹膜透析和血液透析部门进行为期三个月的问卷调查。结果调查问卷83份,年龄(1 ~ 14)岁,平均年龄8.5±3.9岁。(47.6%)对自己的知识非常满意,(29.5%)对自己的知识非常满意。结论CKD患者照护者的情感满意度高于对信息获取量的满意度。不同的人口统计数据可能会影响他们接受坏消息的方式。这种不满表明医生的沟通技巧有待提高。
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引用次数: 1
Skin in the game: Video-game–related cutaneous pathologies in adolescents 游戏中的皮肤:青少年与电子游戏相关的皮肤病变
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2019.09.002
Georgia Kyriakou , Apostolos Glentis

Background

Following the inception of video games and the subsequent development of progressive innovations in videogame technology, many reports of videogame-related dermatologic conditions soon emerged in literature. Children and adolescents, in particular, are among the most avid consumers of online digital entertainment.

Methods

In an effort to better detail the impacts of these cutaneous manifestations and provide recommendations for injury prevention as it relates to video games, we performed an extensive systems-based literature review pertaining to the clinical features, etiology, diagnosis, and treatment of reported cases of dermatoses resulting from the misuse of video games.

Results

A literature review using PubMed, SCOPUS, Ovid MEDLINE and EMBASE was performed. Hardware implicated in the reported cases include video games consoles, personal computers, laptop computers, mobile phones and tablets. The dermatologic conditions are primarily localized to the extremities, particularly the palms and fingers. The majority are associated with repetitive friction and trauma, as well as allergic contact sensitivities. For all cutaneous manifestations induced by video gaming, early recognition and removal of the offending agent was most often described as effective in symptom resolution.

Conclusions

The universal use and pervasive popularity of video games for recreational purposes present an emerging dermatological concern. As videogames become increasingly advanced and immersive, various cutaneous conditions arising from intensive gaming will likely become common over time. Consequently, it is critical that dermatologists consider video games with a high index of suspicion when encountering dermatological ailments in underage patients engaging in persistent gaming behavior.

随着电子游戏的出现和电子游戏技术的进步创新,许多与电子游戏相关的皮肤病的报道很快出现在文献中。尤其是儿童和青少年,是在线数字娱乐最狂热的消费者。方法为了更好地详细描述这些皮肤表现的影响,并提供与电子游戏相关的伤害预防建议,我们进行了广泛的基于系统的文献综述,涉及滥用电子游戏导致的皮肤病的临床特征、病因、诊断和治疗。结果采用PubMed、SCOPUS、Ovid MEDLINE、EMBASE进行文献回顾。报道中涉及的硬件包括视频游戏机、个人电脑、笔记本电脑、手机和平板电脑。皮肤病主要局限于四肢,特别是手掌和手指。大多数与反复摩擦和创伤以及过敏性接触敏感有关。对于所有由电子游戏引起的皮肤表现,早期识别和去除有害物质通常被描述为有效的症状解决。以娱乐为目的的电子游戏的普遍使用和普及引起了人们对皮肤病学的关注。随着电子游戏变得越来越先进和具有沉浸感,由密集游戏引起的各种皮肤状况可能会随着时间的推移而变得普遍。因此,皮肤科医生在遇到持续玩游戏的未成年患者患有皮肤病时,必须对电子游戏抱有高度的怀疑。
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引用次数: 6
Decisions and outcome for infants born near the limit of viability 接近生存能力极限的婴儿的决定和结果
Q2 Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.ijpam.2020.03.008
Fahad Al Hazzani , Saleh Al Alaiyan , Mohammed Bin Jabr , Abdulaziz Binmanee , Mahmoud Shaltout , Yazeed Moqbil Al Motairy , Abdulhameed Sami Qashqary , Abdullah Saleh Al Dughaither

Background

Initiation or withholding life support at birth on infants born prematurely near the limit of viability is not an easy decision, with wide variation in practice around the world. Our aim was to review the outcome of preterm infants born near the limit of viability at 23–25 weeks gestation in our institution, with regard to resuscitation decision, survival, and major outcome measures.

Methods

We included all live newborn infants born prematurely at 23–25 weeks gestation at King Faisal Specialist Hospital and Research Centre from January 2006 to December 2015. We collected data on resuscitation decisions, survival, and major neonatal morbidities such as severe brain injury, severe retinopathy of prematurity, and bronchopulmonary dysplasia.

Results

Between January 1, 2006 and December 31, 2015, 97 infants with a gestational age (GA) of 23–25 weeks gestation were admitted; 23, 42, and 32 infants were born at 23, 24, and 25 weeks gestation, respectively. At 23 weeks gestation, full support was initiated in 87% of patients and later on support was withheld in 17.4% of patients, finally 13% of patients survived to discharge. At 24 weeks, full support was initiated in 97.6% of patients, then withheld in 7.1% of patients, and ultimately 59.5% survived. At 25 weeks, full support was initiated in 93.8% of patients, then withheld in 15.6% of patients, and ultimately 62.5% survived. In terms of survival with and without the three major neonatal morbidities, at 23 weeks gestation, no infant survived without any morbidity as compared to 7.1% and 28.1% at 24 and 25 weeks, respectively. The incidence of survival with 1 major morbidity was 8.7%, 30.9%, and 34.4% at 23, 24, and 25 weeks, respectively, the incidence of survival with 2 major morbidities was 0%, 19%, and 0% at 23, 24, and 25 weeks, respectively, and the incidence of survival with 3 major morbidities was 4.3%, 2.4%, and 0% at 23, 24, and 25 weeks, respectively.

Conclusion

In our patient cohort, survival and survival without major neonatal morbidity were very low at 23 weeks gestation, but it improved gradually as gestational age advanced.

对接近生存能力极限的早产儿启动或停止生命支持并不是一个容易的决定,在世界各地的实践中存在很大差异。我们的目的是回顾23-25周妊娠时接近生存能力极限的早产儿的结局,包括复苏决策、存活率和主要结局指标。方法纳入2006年1月至2015年12月在费萨尔国王专科医院和研究中心出生的所有23-25周早产儿。我们收集了复苏决策、存活率和主要新生儿发病率(如严重脑损伤、早产儿严重视网膜病变和支气管肺发育不良)的数据。结果2006年1月1日至2015年12月31日共收治胎龄23 ~ 25周的新生儿97例;23名、42名和32名婴儿分别在妊娠23周、24周和25周出生。在妊娠23周时,87%的患者开始完全支持,17.4%的患者随后停止支持,最终13%的患者存活至出院。在24周时,97.6%的患者开始完全支持,7.1%的患者停止支持,最终59.5%的患者存活。在25周时,93.8%的患者开始完全支持,15.6%的患者停止支持,最终62.5%的患者存活。在有和没有三种主要新生儿疾病的生存率方面,在妊娠23周时,没有婴儿存活而没有任何疾病,而在24周和25周时分别为7.1%和28.1%。1种主要发病的生存率在23、24、25周时分别为8.7%、30.9%、34.4%,2种主要发病的生存率在23、24、25周时分别为0%、19%、0%,3种主要发病的生存率在23、24、25周时分别为4.3%、2.4%、0%。结论在我们的患者队列中,妊娠23周的生存率和无重大新生儿发病率的生存率都很低,但随着胎龄的增加生存率逐渐提高。
{"title":"Decisions and outcome for infants born near the limit of viability","authors":"Fahad Al Hazzani ,&nbsp;Saleh Al Alaiyan ,&nbsp;Mohammed Bin Jabr ,&nbsp;Abdulaziz Binmanee ,&nbsp;Mahmoud Shaltout ,&nbsp;Yazeed Moqbil Al Motairy ,&nbsp;Abdulhameed Sami Qashqary ,&nbsp;Abdullah Saleh Al Dughaither","doi":"10.1016/j.ijpam.2020.03.008","DOIUrl":"10.1016/j.ijpam.2020.03.008","url":null,"abstract":"<div><h3>Background</h3><p>Initiation or withholding life support at birth on infants born prematurely near the limit of viability is not an easy decision, with wide variation in practice around the world. Our aim was to review the outcome of preterm infants born near the limit of viability at 23–25 weeks gestation in our institution, with regard to resuscitation decision, survival, and major outcome measures.</p></div><div><h3>Methods</h3><p>We included all live newborn infants born prematurely at 23–25 weeks gestation at King Faisal Specialist Hospital and Research Centre from January 2006 to December 2015. We collected data on resuscitation decisions, survival, and major neonatal morbidities such as severe brain injury, severe retinopathy of prematurity, and bronchopulmonary dysplasia.</p></div><div><h3>Results</h3><p>Between January 1, 2006 and December 31, 2015, 97 infants with a gestational age (GA) of 23–25 weeks gestation were admitted; 23, 42, and 32 infants were born at 23, 24, and 25 weeks gestation, respectively. At 23 weeks gestation, full support was initiated in 87% of patients and later on support was withheld in 17.4% of patients, finally 13% of patients survived to discharge. At 24 weeks, full support was initiated in 97.6% of patients, then withheld in 7.1% of patients, and ultimately 59.5% survived. At 25 weeks, full support was initiated in 93.8% of patients, then withheld in 15.6% of patients, and ultimately 62.5% survived. In terms of survival with and without the three major neonatal morbidities, at 23 weeks gestation, no infant survived without any morbidity as compared to 7.1% and 28.1% at 24 and 25 weeks, respectively. The incidence of survival with 1 major morbidity was 8.7%, 30.9%, and 34.4% at 23, 24, and 25 weeks, respectively, the incidence of survival with 2 major morbidities was 0%, 19%, and 0% at 23, 24, and 25 weeks, respectively, and the incidence of survival with 3 major morbidities was 4.3%, 2.4%, and 0% at 23, 24, and 25 weeks, respectively.</p></div><div><h3>Conclusion</h3><p>In our patient cohort, survival and survival without major neonatal morbidity were very low at 23 weeks gestation, but it improved gradually as gestational age advanced.</p></div>","PeriodicalId":36646,"journal":{"name":"International Journal of Pediatrics and Adolescent Medicine","volume":"8 2","pages":"Pages 98-101"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijpam.2020.03.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38991742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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International Journal of Pediatrics and Adolescent Medicine
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