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High tibial osteotomy achieves unloading of the medial tibiofemoral compartment irrespective of arthritic status or medial collateral ligament release: A biomechanical assessment 胫骨高位截骨实现了胫骨内侧股间室的卸载,而不考虑关节炎状态或内侧副韧带的释放:生物力学评估。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-21 DOI: 10.1002/jeo2.70633
Hassan Syed, Aadil Mumith, David Wasserstein, Naveen Chandrashekar, Aaron Nauth, Cari Whyne, Sebastian Tomescu

Purpose

The purpose of this study was to determine the impact of (1) healthy versus arthritic knees and (2) partial versus complete release of the superficial medial collateral ligament (sMCL) on tibiofemoral compartment pressures at varying mechanical axis alignments following medial open-wedge high tibial osteotomy (MOW-HTO).

Methods

Contact pressure (CP) was measured in seven cadaver knees (four healthy; three arthritic) under 1000 N axial load. Tests were conducted at constitutional alignment and MOW-HTO alignment corrections to 50%, 55%, 60% and 65% of the tibial plateau width (TPW) with the sMCL intact and repeated at each alignment following a partial and complete sMCL release. Linear mixed-effects models assessed differences in tibiofemoral CP with factors (1) arthritic status and alignment and (2) alignment and sMCL condition. Main effects were assessed for each factor followed by pairwise comparisons when significant.

Results

Medial CP in healthy and arthritic knees did not differ in response to varying alignment corrections (p = 0.103). The interaction of alignment and sMCL condition was not significant (p = 0.61). With the sMCL intact, altering alignment was found to significantly impact medial CP (p = 0.01). Medial CP significantly decreased from constitutional alignment to 55% and 60% of TPW by 19.0% and 13.9%, respectively (p = 0.02; p = 0.02). Additionally, medial CP at 55% of TPW was found to be 6.6% lower than at 50% of TPW (p = 0.046) and 10.4% lower than at 65% TPW (p = 0.03). sMCL release did not impact medial CP (p = 0.24) but significantly increased lateral CP by 10.8% when completely released (p < 0.001).

Conclusion

The presence of medial compartment arthritis may not be a significant factor in the loading biomechanics of cadaver knees secondary to MOW-HTO corrections. MOW-HTO correction to 55% of TPW was most effective in decreasing medial CP. sMCL release did not impact medial CP; however, it significantly increased lateral CP when the sMCL was completely released.

Level of Evidence

NA, cadaveric study.

目的:本研究的目的是确定(1)健康膝关节与关节炎膝关节和(2)部分或完全释放浅内侧副韧带(sMCL)对内侧开楔高位胫骨截骨(MOW-HTO)后不同机械轴对齐时胫股间室压力的影响。方法:测量7具尸体膝关节在1000 N轴向载荷下的接触压力(CP)。在sMCL完整的情况下,进行体位对齐和MOW-HTO对齐校正至胫骨平台宽度(TPW)的50%、55%、60%和65%的测试,并在部分和完全sMCL释放后重复每次对齐。线性混合效应模型评估了胫骨股骨CP与以下因素的差异:(1)关节炎状态和排列;(2)排列和sMCL状况。评估每个因素的主要影响,当显著时进行两两比较。结果:健康膝关节和关节炎膝关节内侧CP对不同对齐矫正的反应没有差异(p = 0.103)。对齐与sMCL条件的交互作用不显著(p = 0.61)。在sMCL完整的情况下,改变对内侧CP有显著影响(p = 0.01)。内侧CP从体质对齐到TPW的55%和60%,分别显著下降19.0%和13.9% (p = 0.02; p = 0.02)。此外,55% TPW时内侧CP比50% TPW时低6.6% (p = 0.046),比65% TPW时低10.4% (p = 0.03)。sMCL释放不影响内侧CP (p = 0.24),但完全释放后,外侧CP显著增加10.8% (p结论:内侧室关节炎的存在可能不是MOW-HTO矫正后尸体膝关节负荷生物力学的重要因素。MOW-HTO矫正至TPW的55%对降低内侧CP最有效。sMCL释放不影响内侧CP;然而,当sMCL完全释放时,它显著增加了侧位CP。证据等级:NA,尸体研究。
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引用次数: 0
Current concepts and future perspective of muscle function tests to inform return to sport decision-making after ACLR: A narrative review 目前的概念和未来的观点,肌肉功能测试,以告知重返运动决策后ACLR:叙述性回顾。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-21 DOI: 10.1002/jeo2.70643
Rebecca Hamrin Senorski, Ramana Piussi, Johan Högberg, Axel Sundberg, Jakob Lindskog, Robert Prill, Eric Hamrin Senorski

An injury to the anterior cruciate ligament (ACL) can be sustained in sports participation during situations such as offensive cutting, landing from a jump, or defensive pressing. Despite treatment with surgical reconstruction and/or rehabilitation, only 55%–84% of patients return to sport (RTS) after treatment, and second ACL injury rates remain as high as 25% in young athletes. To reduce the risk of second ACL injury, clinicians commonly use muscle strength tests, hop tests, and patient-reported outcomes (PROs) to evaluate readiness for RTS. These tools have become central in clinical decision-making, yet significant challenges remain. Current tests typically rely on limb symmetry index (LSI) thresholds, with ≥90% LSI commonly recommended as a clearance criterion for RTS. However, these cut-offs have shown poor predictive value for second ACL injury risk and may be misleading. The LSI also fails to account for pre-injury strength, bilateral deficits, or compensatory movement strategies. Hop tests provide additional insights into explosiveness and load absorption but emphasise distance or repetitions rather than movement quality, missing key biomechanical risk factors. Similarly, while PROs aim to capture the psychological dimension of recovery, they cannot be used in isolation to determine readiness for RTS. Collectively, these evaluation tools provide only snapshots of recovery and do not adequately reflect the chaotic, multidimensional demands of sport. The research gap lies not in the absence of tests, but in their limited transferability, standardisation, and contextual relevance. Current tests should not be viewed as a simple pass-or-fail clearance point, but as guidance for informed decision-making in rehabilitation. Continuous evaluation across physical and psychological domains can help clinicians tailor progression, motivate patients, and support safer transitions toward sport. This narrative review explores the current state, limitations, and future directions of RTS testing in order the bridge the gap between clinical measures and the chaotic, high-demand realities of sport.

Level of Evidence

Level III.

前十字韧带(ACL)的损伤可能在参加体育运动时持续发生,如进攻性的切入、起跳落地或防守性的压迫。尽管进行了手术重建和/或康复治疗,但只有55%-84%的患者在治疗后恢复运动(RTS),年轻运动员的二次ACL损伤率仍然高达25%。为了降低第二次ACL损伤的风险,临床医生通常使用肌力测试、跳跃测试和患者报告的结果(PROs)来评估RTS的准备情况。这些工具已成为临床决策的核心,但仍存在重大挑战。目前的测试通常依赖肢体对称指数(LSI)阈值,LSI≥90%通常被推荐作为RTS的清除标准。然而,这些截断值对第二次ACL损伤风险的预测价值较差,可能会产生误导。LSI也不能解释损伤前的力量、双侧缺陷或补偿性运动策略。跳跃测试提供了对爆发力和负荷吸收的额外见解,但强调距离或重复次数而不是运动质量,忽略了关键的生物力学风险因素。类似地,虽然pro旨在捕捉恢复的心理维度,但它们不能单独用于确定RTS的准备情况。总的来说,这些评估工具只提供了恢复的快照,并没有充分反映体育的混乱,多维需求。研究差距不在于缺乏测试,而在于测试的可转移性、标准化和上下文相关性有限。目前的测试不应被视为一个简单的通过或不通过的清除点,而应被视为康复过程中知情决策的指导。身体和心理领域的持续评估可以帮助临床医生调整进展,激励患者并支持更安全的运动过渡。这篇叙述性综述探讨了RTS测试的现状、局限性和未来方向,以便弥合临床测量与体育运动中混乱、高要求的现实之间的差距。证据等级:三级。
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引用次数: 0
Increased tibial tubercle torsion is associated with advanced lateral patellofemoral osteoarthritis 胫骨结节扭转增加与晚期外侧髌骨关节炎有关。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70637
Maksym Polt, Lukas Jud, Sandro Hodel, Andreas Flury, Benjamin Fritz, Lazaros Vlachopoulos, Sandro F. Fucentese
<div> <section> <h3> Purpose</h3> <p>To investigate whether the emerging anatomical parameters of the patellofemoral (PF) joint, including tibial tubercle torsion (TT torsion), the sagittal tibial tuberosity–trochlear groove (sTT–TG) distance, the tibial tuberosity rotational angle (TT–RA), the tibiofemoral rotation and tibial tuberosity lateralisation (TT lateralisation), are associated with advanced lateral patellofemoral osteoarthritis (PFOA).</p> </section> <section> <h3> Methods</h3> <p>This retrospective study analysed patients from a preoperative total knee arthroplasty workup database. PF cartilage lesions of International Cartilage Repair Society Grade 3 or higher were defined as advanced. TT torsion, sTT–TG, TT–RA and TT lateralisation were assessed based on computed tomography imaging. Additionally, tibiofemoral rotation, tibial tuberosity–trochlear groove distance, Caton–Deschamps index, femoral antetorsion, tibial torsion and the hip–knee–ankle (HKA) angle were also included in the analysis. Binary logistic regression analysis and Mann–Whitney <i>U</i> test were used to examine associations between the advanced PFOA and the measured anatomical parameters.</p> </section> <section> <h3> Results</h3> <p>Fifty-two knees/patients (35 females and 17 males) could be included: 20 with advanced lateral PFOA, 13 with advanced medial PFOA and 19 without advanced PFOA. Femoral antetorsion (odds ratio [OR] = 1.094, 95% confidence interval [CI] = 1.029–1.164; <i>p</i> = 0.004) and valgus HKA angle (OR = 1.152, 95% CI = 1.066–1.247; <i>p</i> < 0.001) met the Bonferroni-adjusted threshold (<i>p</i> < 0.005) for association with lateral PFOA. TT torsion was significant at the 0.05 level but not after the Bonferroni adjustment (OR = 1.138, 95% CI = 1.027–1.260; <i>p</i> = 0.013). Analysing isolated lateral vs. medial PFOA, higher TT torsion and femoral torsion, as well as valgus HKA angle, exhibited a Bonferroni-adjusted statistically significant correlation with advanced lateral PFOA (<i>p</i> = 0.003, <i>p</i> < 0.001 and <i>p</i> < 0.002, respectively).</p> </section> <section> <h3> Conclusion</h3> <p>TT torsion is associated with advanced lateral PFOA and may represent an additional risk factor. This finding underscores the substantial role of rotational malalignment in the pathogenesis of lateral PFOA. Recognising the role of TT torsion and its intercorrelation with the HKA angle and femoral antetorsion may refine clinical assessment of PF conditions and inform surgical strategies.</p> </section>
目的:探讨髌股关节(PF)新出现的解剖学参数,包括胫骨结节扭转(TT扭转)、矢状胫骨结节-滑车沟(sTT-TG)距离、胫骨结节旋转角(TT- ra)、胫股旋转和胫骨结节偏侧(TT偏侧)是否与晚期外侧髌骨股骨骨关节炎(PFOA)相关。方法:本回顾性研究分析了全膝关节置换术术前随访数据库中的患者。国际软骨修复学会分级3级及以上的PF软骨病变定义为晚期。TT扭转、sTT-TG、TT- ra和TT侧化基于计算机断层成像进行评估。此外,胫骨股骨旋转、胫骨结节-滑车沟距离、Caton-Deschamps指数、股骨前旋、胫骨扭转和髋关节-膝关节-踝关节(HKA)角度也被纳入分析。采用二元logistic回归分析和Mann-Whitney U检验检验晚期PFOA与测量的解剖参数之间的关系。结果:共纳入52例患者(女35例,男17例),其中进展性外侧PFOA 20例,进展性内侧PFOA 13例,无进展性PFOA 19例。股前扭力(优势比[OR] = 1.094, 95%可信区间[CI] = 1.029-1.164; p = 0.004)和外翻HKA角(OR = 1.152, 95% CI = 1.066-1.247; p p p = 0.013)。分析孤立的外侧PFOA与内侧PFOA,较高的TT扭转和股扭转以及外翻HKA角,显示出bonferroni调整后的统计学显著相关性(p = 0.003, p p)。结论:TT扭转与晚期外侧PFOA相关,可能是一个额外的危险因素。这一发现强调了旋转不对准在外侧PFOA发病机制中的重要作用。认识到TT扭转的作用及其与HKA角度和股前旋的相互关系,可以改善PF病情的临床评估并为手术策略提供信息。证据等级:三级。
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引用次数: 0
Comparison of the accuracy of two guiding devices for femoral tunnel position in anterior cruciate ligament reconstruction surgery: A radiographic study 前交叉韧带重建手术中两种引导装置股骨隧道定位精度的比较:影像学研究。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70632
Pei Zhao, Shixin Nie, Zhi Chen, Chengjian Wu, Jiajun Lin, Chengjie Lian, Hua Zhang

Purpose

This study evaluated the comparative efficacy of two guiding devices in positioning the femoral tunnel in the ‘Isometric, Direct insertion, Eccentrically located, Anatomical, Low tension’ (I.D.E.A.L.) zone during anterior cruciate ligament reconstruction.

Methods

A retrospective analysis was conducted on 64 patients. Group A (32 cases) used traditional tools, while Group B (32 cases) used the modified locator. Postoperative three-dimensional computed tomography reconstructions of the femoral condyle were performed, and tunnel position (using the quadrant method) and the distance from the tunnel's posterior edge to the lateral condyle posterior wall were measured. Statistical analysis was performed to compare the differences between the two groups.

Results

The mean femoral tunnel centre positions were 30.3% ± 4.5% (deep–shallow) and 25.5% ± 9.6% (high–low) in Group A, and 25.9% ± 3.9% (deep–shallow) and 26.6% ± 5.8% (high–low) in Group B. The ideal I.D.E.A.L. tunnel centre was defined at (28.4, 22.2). No significant difference in dispersion was observed between the two groups. But the tunnel centre in Group B is more concentrated near the posterior region of the femoral footprint. The distance from the posterior tunnel edge to the posterior wall was 3.5 ± 1.7 mm in Group A and 2.2 ± 1.0 mm in Group B, showing a significant difference. Each group had 1 case of the posterior wall rupture; the rupture rate did not differ significantly between the groups.

Conclusion

The modified locator facilitates femoral tunnel placement closer to the posterior wall, which promotes the biomechanical conditions required for optimal graft isometry and low tension.

Level of Evidence

Level IV and V, retrospective study.

目的:本研究评估了两种导向装置在前交叉韧带重建中“等距、直接插入、偏心定位、解剖、低张力”(I.D.E.A.L.)区定位股骨隧道的比较效果。方法:对64例患者进行回顾性分析。A组(32例)使用传统工具,B组(32例)使用改良定位器。术后对股骨髁进行三维计算机断层重建,并测量隧道位置(使用象限法)和隧道后缘到外侧髁后壁的距离。通过统计学分析比较两组患者的差异。结果:A组平均股骨隧道中心位置为30.3%±4.5%(深浅)和25.5%±9.6%(高低),b组为25.9%±3.9%(深浅)和26.6%±5.8%(高低),理想的i.d.e.a.l隧道中心位置为(28.4,22.2)。两组间弥散度无显著差异。但B组的隧道中心更集中在股掌后区附近。A组隧道后缘至后壁的距离为3.5±1.7 mm, B组为2.2±1.0 mm,差异有统计学意义。各组各有1例后壁破裂;两组间破裂率无显著差异。结论:改良定位器使股骨隧道放置更靠近后壁,促进了最佳移植物等距和低张力所需的生物力学条件。证据等级:IV级和V级,回顾性研究。
{"title":"Comparison of the accuracy of two guiding devices for femoral tunnel position in anterior cruciate ligament reconstruction surgery: A radiographic study","authors":"Pei Zhao,&nbsp;Shixin Nie,&nbsp;Zhi Chen,&nbsp;Chengjian Wu,&nbsp;Jiajun Lin,&nbsp;Chengjie Lian,&nbsp;Hua Zhang","doi":"10.1002/jeo2.70632","DOIUrl":"10.1002/jeo2.70632","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study evaluated the comparative efficacy of two guiding devices in positioning the femoral tunnel in the ‘Isometric, Direct insertion, Eccentrically located, Anatomical, Low tension’ (I.D.E.A.L.) zone during anterior cruciate ligament reconstruction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on 64 patients. Group A (32 cases) used traditional tools, while Group B (32 cases) used the modified locator. Postoperative three-dimensional computed tomography reconstructions of the femoral condyle were performed, and tunnel position (using the quadrant method) and the distance from the tunnel's posterior edge to the lateral condyle posterior wall were measured. Statistical analysis was performed to compare the differences between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean femoral tunnel centre positions were 30.3% ± 4.5% (deep–shallow) and 25.5% ± 9.6% (high–low) in Group A, and 25.9% ± 3.9% (deep–shallow) and 26.6% ± 5.8% (high–low) in Group B. The ideal I.D.E.A.L. tunnel centre was defined at (28.4, 22.2). No significant difference in dispersion was observed between the two groups. But the tunnel centre in Group B is more concentrated near the posterior region of the femoral footprint. The distance from the posterior tunnel edge to the posterior wall was 3.5 ± 1.7 mm in Group A and 2.2 ± 1.0 mm in Group B, showing a significant difference. Each group had 1 case of the posterior wall rupture; the rupture rate did not differ significantly between the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The modified locator facilitates femoral tunnel placement closer to the posterior wall, which promotes the biomechanical conditions required for optimal graft isometry and low tension.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV and V, retrospective study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12814215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic-assisted restricted kinematic alignment in total knee arthroplasty: A multicenter retrospective assessment of coronal phenotypes and early postoperative outcomes 全膝关节置换术中机器人辅助受限运动学对齐:冠状表型和早期术后结果的多中心回顾性评估。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70646
Ravi Teja Rudraraju, Sanjay Bhalchandra Londhe, Ponnanna Karineravanda Machaiah, Supreet Bajwa, Kunal Aneja, Police Jayaram Reddy, Kanakanala Jangi Reddy, Dolly Singh
<div> <section> <h3> Purpose</h3> <p>The Coronal Plane Alignment of the Knee (CPAK) classification enables phenotype-based total knee arthroplasty (TKA), but its application in robotic-assisted TKA (RATKA) remains underexplored. We aim to describe the distribution of CPAK phenotypes in patients undergoing RATKA using a restricted kinematic alignment (rKA) protocol, evaluate alignment correction within rKA boundaries and report early postoperative functional outcomes. We hypothesized that RATKA would achieve alignment targets within the rKA range while demonstrating expected postoperative functional recovery.</p> </section> <section> <h3> Methods</h3> <p>This multicenter retrospective study included 200 patients with primary knee osteoarthritis between June and November 2024 at five high-volume centres. All procedures followed a rKA protocol, with target correction within ±3° of constitutional alignment. CPAK distribution, demographic variations, achieved alignment and early postoperative functional outcomes measured by the Knee Injury and Osteoarthritis Outcome Score (KOOS) and Forgotten Joint Score (FJS) were analysed.</p> </section> <section> <h3> Results</h3> <p>The cohort (mean age 62.9 years; 60.5% female) showed preoperative arithmetic hip–knee–ankle angle of −5.8° ± 4.6° and joint line obliquity of 173.2° ± 4.1°, predominantly varus (71.5% Type I). Type I alignment was more frequent in males (73.4%), females (70.2%) and those aged >61 years. Of the 71.5% CPAK Type I, 63.5% remained Type I with correction within 0° ± 3°, while 8% were corrected to Type II. All achieved alignment within rKA limits (mean postoperative hip–knee–ankle 173.0° ± 3.2°). Mean postoperative lateral distal femoral angle and medial proximal tibial angle were 85.1° and 87.7°, respectively. Significant improvements were observed in KOOS (80.9 ± 2.3 vs. 40.6 ± 3.5, <i>p</i> < 0.05) and FJS (75.9 ± 1.4 vs. 49.8 ± 1.3, <i>p</i> < 0.05) at 6 months. No early revisions occurred.</p> </section> <section> <h3> Conclusion</h3> <p>RATKA performed with a rKA strategy, achieved postoperative alignment within planned rKA limits across CPAK phenotypes. Early functional outcomes at 6 months were satisfactory and consistent with expected postoperative recovery following TKA; however, in the absence of a comparator group, these improvements cannot be attributed solely to the robotic platform or alignment strategy.</p> </section> <section> <h3> Level of Evidence</h3> <p>Level II,
目的:膝关节冠状面排列(CPAK)分类使基于表型的全膝关节置换术(TKA)成为可能,但其在机器人辅助全膝关节置换术(RATKA)中的应用仍未得到充分探索。我们的目的是通过限制性运动学对齐(rKA)方案描述RATKA患者中CPAK表型的分布,评估rKA边界内的对齐纠正,并报告早期术后功能结果。我们假设RATKA将在rKA范围内达到对齐目标,同时显示预期的术后功能恢复。方法:这项多中心回顾性研究纳入了2024年6月至11月在5个高容量中心进行的200例原发性膝关节骨关节炎患者。所有手术均遵循rKA方案,目标校正在±3°内。分析CPAK分布、人口统计学变化、实现对齐以及膝关节损伤和骨关节炎结局评分(oos)和遗忘关节评分(FJS)测量的早期术后功能结果。结果:患者(平均年龄62.9岁,女性占60.5%)术前算术髋关节-膝关节-踝关节角为-5.8°±4.6°,关节线倾角为173.2°±4.1°,以内翻为主(71.5%为I型)。I型配型在男性(73.4%)、女性(70.2%)和年龄在100 ~ 61岁的人群中更为常见。在71.5%的CPAK I型中,63.5%仍为I型,矫正在0°±3°范围内,8%矫正为II型。所有患者均在rKA范围内实现对齐(术后髋关节-膝关节-踝关节平均173.0°±3.2°)。术后平均股骨外侧远端角为85.1°,胫骨内侧近端角为87.7°。KOOS有显著改善(80.9±2.3 vs. 40.6±3.5,p . p .)。结论:采用rKA策略进行RATKA,在CPAK表型的计划rKA限制内实现了术后对齐。TKA术后6个月的早期功能结果令人满意,与预期的术后恢复一致;然而,在没有比较组的情况下,这些改进不能仅仅归功于机器人平台或对准策略。证据等级:二级,回顾性研究。
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引用次数: 0
Deep learning applied to standard radiographs improves detection of implant loosening in total knee arthroplasty: A proof-of-concept study 应用于标准x线片的深度学习提高了全膝关节置换术中假体松动的检测:一项概念验证研究。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70611
Kelly Mills, Guido A. de Jong, Simon N. van Laarhoven, Thomas J. J. Maal, Petra J. C. Heesterbeek
<div> <section> <h3> Purpose</h3> <p>Implant loosening is a common cause of failure in total knee arthroplasty, and for appropriate treatment, the correct diagnosis is of vital importance. Detection is challenging as radiographs only reveal obvious cases, computed tomography (CT) scans are hindered by metal artifacts, and bone scintigraphy lacks specificity, while all methods are time-consuming and/or involve radiation exposure. This proof-of-concept study aimed to develop a deep learning (DL) tool to detect implant loosening using a set of two-dimensional (2D) radiographs.</p> </section> <section> <h3> Methods</h3> <p>A total of 307 radiograph sets (anteroposterior and lateral) were collected, including 159 loose and 148 fixed primary knee implants (confirmed intraoperatively during revision surgery). Images were square-cropped, centred on the implant, horizontally flipped for left knees, resized to 512 × 512 pixels and standardized for grayscale. A dual InceptionV3 DL algorithm was trained using fivefold cross-validation. Performance was assessed using sensitivity, specificity, accuracy and receiver operating characteristic curves, with corresponding area under the curve (AUC) and compared to routine radiological reports.</p> </section> <section> <h3> Results</h3> <p>The mean ± standard deviation (SD) sensitivity, specificity and accuracy over the fivefolds were 71.7% ± 10.7%, 87.0% ± 14.2% and 79.2% ± 4.0%, respectively. The overall AUC was 0.81, confidence interval (CI): [0.77–0.85]. The radiological report predictions reached a sensitivity of 51.3%, specificity of 99.2% and accuracy of 73.2%. The algorithm predicted significantly more cases correctly compared to standard radiological evaluations by a musculoskeletal specialized radiologist (<i>p</i> = 0.005).</p> </section> <section> <h3> Conclusions</h3> <p>This proof-of-concept study demonstrated the feasibility of training a deep-learning algorithm using 2D radiographs to detect implant loosening. Notably, the algorithm outperformed routine radiological evaluations, highlighting its potential to enhance the detection of loosening. These results are promising, considering the limited dataset. This tool could be valuable for patients experiencing issues after knee replacement surgery, helping to rule out implant loosening while reducing analysis time, radiation exposure and healthcare costs.</p> </section> <section> <h3> Level of Evidence</h3> <p>Level III.</p> </section>
目的:假体松动是全膝关节置换术失败的常见原因,正确的诊断对正确的治疗至关重要。检测具有挑战性,因为x线片只能显示明显的病例,计算机断层扫描(CT)扫描受到金属伪影的阻碍,骨显像缺乏特异性,而所有方法都耗时且/或涉及辐射暴露。这项概念验证研究旨在开发一种深度学习(DL)工具,通过一组二维(2D) x线片检测种植体松动。方法:共收集307组(正位和侧位)x线片,包括159个松动膝关节假体和148个固定膝关节假体(术中翻修术中确认)。图像被正方形裁剪,以植入物为中心,水平翻转左膝,调整大小为512 × 512像素,并标准化为灰度。采用五重交叉验证训练了双InceptionV3深度学习算法。通过灵敏度、特异性、准确性和受试者工作特征曲线,以及相应的曲线下面积(AUC),并与常规放射学报告进行比较,评估疗效。结果:5倍的平均±标准差(SD)灵敏度、特异度和准确度分别为71.7%±10.7%、87.0%±14.2%和79.2%±4.0%。总体AUC为0.81,置信区间(CI):[0.77-0.85]。放射学报告预测灵敏度为51.3%,特异性为99.2%,准确性为73.2%。与肌肉骨骼专业放射科医生的标准放射学评估相比,该算法预测的病例正确率明显更高(p = 0.005)。结论:这项概念验证研究证明了使用二维x线片训练深度学习算法来检测种植体松动的可行性。值得注意的是,该算法优于常规放射学评估,突出了其增强松脱检测的潜力。考虑到有限的数据集,这些结果是有希望的。该工具对于膝关节置换术后出现问题的患者可能很有价值,有助于排除植入物松动,同时减少分析时间、辐射暴露和医疗费用。证据等级:三级。
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引用次数: 0
Validity and reliability of the French version of the quick-FAAM (Q-FAAM-F) among patients undergoing anatomic ankle ligament reconstruction 法国版快速faam (Q-FAAM-F)在解剖踝关节韧带重建患者中的效度和信度。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70644
Ibrahim Saliba, Olivier Grimaud, Vincent Fontanier, Brice Picot, Frederic Khiami, Gregoire Rougereau, Yoann Bohu, Nicolas Lefevre, Alexandre Hardy

Purpose

To evaluate the validity and reliability of the French version of the Quick Foot and Ankle Ability Measure (Q‑FAAM‑F) in French‑speaking patients with chronic lateral ankle instability (CLAI).

Methods

We conducted a prospective observational cohort in a sports surgery centre with repeated assessments preoperatively, and at 3 and 6 months postoperatively; the primary analysis was cross‑sectional at 6 months. Consecutive CLAI patients undergoing anatomic lateral ankle ligament reconstruction (AALR) were included. Patients completed the Q‑FAAM‑F (12 items derived from the validated French FAAM) alongside the full FAAM, FAOS, ALR‑RSI, CAIT and VAS‑pain. Internal consistency (Cronbach's α), item–total and inter‑item correlations, and construct validity (Pearson's r) were calculated. Discriminant validity used ROC analyses for CLAI status (CAIT < 24) and return to sport (RTS), defined on the RTS continuum as return to the pre‑injury sport at any level at 6 months and treated as an external clinical variable.

Results

Among 275 patients (56% male; median age 32 years), Q‑FAAM‑F showed excellent internal consistency (α = 0.96) and strong item–total correlations (mean r ≈ 0.65). Convergent validity was strong with the FAAM (r = 0.95) and with FAOS and ALR‑RSI; divergent validity was supported by the absence of correlation with CAIT of the nonoperated limb. ROC AUC for CLAI status and RTS were high; optimal cut‑offs were 78.1/100 (CLAI: sensitivity 81.3%, specificity 85.4%) and 80.2/100 (RTS: sensitivity 75.4%, specificity 87.9%).

Conclusion

The Q‑FAAM‑F is a valid and reliable PROM for French‑speaking CLAI patients, suitable for clinical practice and research. Precise AUC‑based thresholds may support clinical decision‑making at 6 months.

Level of Evidence

Level III.

目的:评价法语版快速足踝关节能力量表(Q‑FAAM‑F)在法语区慢性外侧踝关节不稳(CLAI)患者中的效度和可靠性。方法:我们在一家运动外科中心进行了前瞻性观察队列研究,并在术前、术后3个月和6个月进行了反复评估;主要分析是6个月时的横断面分析。连续CLAI患者接受解剖性踝关节外侧韧带重建(AALR)。患者在完成完整的FAAM、FAOS、ALR - RSI、CAIT和VAS - pain测试的同时完成Q - FAAM - F(12个项目来自经过验证的法国FAAM)。计算了内部一致性(Cronbach’s α)、项目总数和项目间相关性以及结构效度(Pearson’s r)。CAIT结果:在275例患者中(56%为男性,中位年龄32岁),Q - FAAM - F表现出良好的内部一致性(α = 0.96)和强项目-总相关性(平均r≈0.65)。FAAM、FAOS和ALR - RSI的收敛效度较强(r = 0.95);未手术肢体与CAIT无相关性,证实了发散效度。CLAI状态和RTS的ROC AUC较高;最佳临界值分别为78.1/100 (CLAI:敏感性81.3%,特异性85.4%)和80.2/100 (RTS:敏感性75.4%,特异性87.9%)。结论:Q‑FAAM‑F是一种有效、可靠的法语语系CLAI患者PROM,适合临床实践和研究。基于AUC的精确阈值可支持6个月时的临床决策。证据等级:三级。
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引用次数: 0
Bone morphology and alignment features are associated with knee kinematics in healthy individuals: A scoping review 健康个体的骨形态和排列特征与膝关节运动学相关:一项范围综述。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70619
Erin Teule, Sebastiaan van de Groes, Nico Verdonschot, Dennis Janssen
<div> <section> <h3> Purpose</h3> <p>The aim of this scoping review was to compose an overview of existing literature on the influence of knee bone morphology and alignment on knee kinematics in healthy individuals.</p> </section> <section> <h3> Methods</h3> <p>This review was conducted according to the methodological frameworks of Arksey and O'Malley and Levac et al. and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. A systematic PubMed search was performed to identify studies examining associations between knee bone morphology or alignment features and knee kinematics during movement in healthy individuals. Data were charted using a standardised form and categorised and summarised by individual bone (femur, tibia or patella) or as alignment feature.</p> </section> <section> <h3> Results</h3> <p>A total of 2402 studies were initially identified. Following duplicate removal and eligibility screening, 29 studies were included. Knee kinematics were assessed using various techniques, including marker-based motion capture systems and advanced dynamic magnetic resonance imaging (MRI) or computed tomography (CT) imaging, across diverse knee movement tasks. Thirteen femoral and seven tibial bone morphology features demonstrated statistically significant associations with knee kinematics, whereas only two patellar bone morphology features were statistically significantly associated. Additionally, sixteen different alignment features showed statistically significant associations with knee kinematics. The features most frequently associated with knee kinematics included lateral trochlear inclination, tibial slope, tibial tuberosity–trochlear groove distance and static patellar tilt angle.</p> </section> <section> <h3> Conclusion</h3> <p>Although many reported associations were supported by only a limited number of studies, this review provides a comprehensive overview of relationships between knee morphology and kinematics in healthy individuals. The findings highlight the importance of considering bone morphology and alignment in kinematic assessment and contribute to a growing understanding of functional knee anatomy. The influence of patellar bone morphology on knee kinematics remains underinvestigated, underscoring the need for standardised, large-scale studies to further advance clinical assessment and biomechanical understanding.</p> </section> <section> <h3> Level of Evidence</h3>
目的:本综述的目的是对健康个体膝关节骨形态和排列对膝关节运动学影响的现有文献进行综述。方法:本综述根据Arksey、O'Malley和Levac等人的方法框架进行,并按照系统评价和荟萃分析扩展范围评价指南的首选报告项目进行报道。我们进行了系统的PubMed检索,以确定健康个体在运动过程中膝关节骨骼形态或排列特征与膝关节运动学之间关系的研究。使用标准化表格绘制数据,并按单个骨骼(股骨、胫骨或髌骨)或对齐特征进行分类和汇总。结果:共有2402项研究被初步确定。经过重复删除和资格筛选,纳入了29项研究。通过不同的膝关节运动任务,使用各种技术评估膝关节运动学,包括基于标记的运动捕捉系统和先进的动态磁共振成像(MRI)或计算机断层扫描(CT)成像。13个股骨和7个胫骨骨形态特征显示与膝关节运动学有统计学意义的关联,而只有2个髌骨形态特征有统计学意义的关联。此外,16种不同的对齐特征显示与膝关节运动学有统计学意义的关联。最常与膝关节运动学相关的特征包括外侧滑车倾斜、胫骨斜度、胫骨结节-滑车沟距离和静态髌骨倾斜角度。结论:尽管许多报道的关联仅得到有限数量研究的支持,但本综述提供了健康个体膝关节形态和运动学之间关系的全面概述。研究结果强调了在运动学评估中考虑骨形态和对齐的重要性,并有助于对功能性膝关节解剖学的理解。髌骨形态对膝关节运动学的影响仍未得到充分研究,因此需要进行标准化、大规模的研究,以进一步推进临床评估和生物力学理解。证据等级:三级。
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引用次数: 0
Limb salvage in multiple revision total knee arthroplasty using customised implants: When sleeves and cones are no longer an option 定制植入物在多次翻修全膝关节置换术中的肢体保留:当套筒和锥体不再是一种选择。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70647
Stefanie Donner, Clemens Gwinner, Henryk Haffer, Carsten Perka, Stephanie Kirschbaum

Purpose

Multiple revision total knee arthroplasty (rTKA) remains highly challenging due to severe bone defects, which often render standard implants unsuitable. This study aimed to evaluate the clinical outcomes, survivorship and complication rates of customised knee implants used in aseptic one-stage rTKA for patients with severe bone defects.

Methods

This study included 16 patients who underwent 18 one-stage rTKAs using custom-made implants due to aseptic loosening between 2016 and 2023. Conventional revision systems failed to provide appropriate femoral or tibial fixation due to severe conical longitudinal bone defects classified as Anderson Orthopaedic Research Institute (AORI) type III. Clinical outcomes were assessed using the knee injury and osteoarthritis outcome score (KOOS), Oxford knee score (OKS), visual analogue scale (VAS) for pain, range of motion (ROM), walking time and procedure-related complications. Implant costs were compared between customised and standard implants.

Results

Mean follow-up was 51 months (range, 24–100), with patients having an average of five previous surgeries (range, 2–8). During follow-up, three patients (17%) reported complications: one periprosthetic fracture, one periprosthetic joint infection and one failure of the modular stem component. Mean KOOS improved from 31 to 80 (p < 0.001), OKS from 47–32 points (p < 0.001) and pain on the VAS decreased from 8.1 to 3.1 (p < 0.001).

Conclusions

Customised implants for one-stage rTKA present a promising cementless fit-and-fill fixation option for patients with severe longitudinal bone defects, particularly when standard knee revision implants, including cones and sleeves, are no longer suitable. Yet, these results are just midterm and small sample size-based and therefore long-term results in larger patient numbers need to be awaited before a final conclusion can be made.

Level of Evidence

Level IV.

目的:由于严重的骨缺损,多次翻修全膝关节置换术(rTKA)仍然具有很高的挑战性,这通常使标准植入物不适合。本研究旨在评估用于严重骨缺损患者的无菌一期全膝关节置换术的定制膝关节植入物的临床结果、生存率和并发症发生率。方法:本研究纳入2016年至2023年期间因无菌性松动使用定制种植体进行18次一期rtka的16例患者。由于安德森骨科研究所(AORI)分类为III型的严重锥形纵向骨缺损,传统的翻修系统无法提供适当的股骨或胫骨固定。临床结果采用膝关节损伤和骨关节炎结局评分(oos)、牛津膝关节评分(OKS)、疼痛视觉模拟评分(VAS)、活动范围(ROM)、步行时间和手术相关并发症进行评估。将定制种植体和标准种植体的成本进行比较。结果:平均随访51个月(范围24-100),患者平均既往手术5次(范围2-8)。在随访期间,3例患者(17%)报告了并发症:1例假体周围骨折,1例假体周围关节感染和1例模块化干组件失效。结论:针对一期rTKA的定制假体为严重纵向骨缺损患者提供了一种很有前途的无骨水泥充填固定选择,特别是当标准的膝关节翻修假体(包括锥体和套筒)不再适用时。然而,这些结果只是基于中期和小样本量的,因此需要等待更多患者数量的长期结果才能得出最终结论。证据等级:四级。
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引用次数: 0
Radiographic medial posterior tibial slope ≥16° predicts multiple revisions after anterior cruciate ligament reconstruction 胫骨内侧后斜度≥16°的x线片预测前交叉韧带重建后的多次修复。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2026-01-19 DOI: 10.1002/jeo2.70624
Mahmut Enes Kayaalp, Jumpei Inoue, Efstathios Konstantinou, Hamit Çağlayan Kahraman, Tunay Erden, Volker Musahl
<div> <section> <h3> Purpose</h3> <p>An increased posterior tibial slope (PTS) has been implicated as a risk factor for anterior cruciate ligament (ACL) graft failure. This matched case–control study aimed to compare radiographic and magnetic resonance imaging (MRI)-based PTS measurements between patients undergoing multiple revision anterior cruciate ligament reconstruction (ACLR) and those with successful primary ACLR and to identify thresholds predictive of high revision risk.</p> </section> <section> <h3> Methods</h3> <p>In this matched case–control study, 156 patients were analysed: 78 patients undergoing multiple revision ACLR and 78 patients with successful primary ACLR. Medial PTS was measured on radiographs, while medial, lateral and PTS difference (PTS asymmetry) were measured on MRI. Group differences were assessed using independent <i>t</i> tests and <i>χ</i><sup>2</sup> tests. Receiver operating characteristic (ROC) analysis identified optimal thresholds, and logistic regression quantified odds ratios (ORs) for multiple revisions per 1° increase in radiographic medial PTS, adjusting for body mass index (BMI), sex, side, height and weight.</p> </section> <section> <h3> Results</h3> <p>Radiographic medial PTS was significantly higher in the multiple-revision group (12.5 ± 3.5° vs. 11.2 ± 3.0°, <i>p</i> = 0.016). ROC analysis identified an optimal medial PTS cutoff of 13° (area under the curve = 0.58, sensitivity = 0.49, specificity = 0.65), but only a PTS ≥ 16° was significantly associated with increased multiple revision risk (OR = 3.10, 95% confidence interval [CI]: 1.14–8.40; <i>p</i> = 0.037; specificity = 0.91; positive predictive value [PPV] = 0.70). MRI-based medial and lateral PTSs, as well as PTS asymmetry, did not differ significantly between groups. Univariate logistic regression demonstrated a 10% increase in odds per 1° increase in radiographic PTS (OR = 1.10, 95% CI: 1.00–1.22, <i>p</i> = 0.049), remaining significant after adjustment for BMI, sex, side, height and weight (adjusted OR = 1.11, 95% CI: 1.01–1.23, <i>p</i> = 0.034). Radiographic medial PTS correlated moderately with MRI-based medial PTS (<i>r</i> = 0.49, <i>p</i> < 0.001), but not with lateral PTS (<i>p</i>: n.s.).</p> </section> <section> <h3> Conclusion</h3> <p>Radiographic medial PTS showed the strongest differentiation between successful primary ACLR and multiple-revision ACLR. A PTS ≥ 16° identifies patients at significantly higher risk of multiple revisions, whereas MRI-based medial PTS, lateral PTS and PTS asymmetry provide no additional discriminato
目的:胫骨后坡(PTS)增加被认为是前交叉韧带(ACL)移植失败的危险因素。这项匹配的病例对照研究旨在比较接受多次前交叉韧带重建(ACLR)翻修的患者和成功进行原发性ACLR翻修的患者之间基于放射学和磁共振成像(MRI)的PTS测量,并确定预测高翻修风险的阈值。方法:在这项匹配的病例对照研究中,对156例患者进行了分析:78例进行了多次改良ACLR, 78例成功进行了原发性ACLR。在x线片上测量内侧PTS,在MRI上测量内侧、外侧和PTS差异(PTS不对称)。采用独立t检验和χ 2检验评估组间差异。受试者工作特征(ROC)分析确定了最佳阈值,logistic回归量化了放射医学PTS每增加1°的多次修订的优势比(ORs),调整了体重指数(BMI)、性别、侧面、身高和体重。结果:多次翻修组放射学内侧PTS明显更高(12.5±3.5°vs 11.2±3.0°,p = 0.016)。ROC分析确定最佳内侧PTS截点为13°(曲线下面积= 0.58,敏感性= 0.49,特异性= 0.65),但只有PTS≥16°与多重翻修风险增加显著相关(OR = 3.10, 95%可信区间[CI]: 1.14-8.40; p = 0.037;特异性= 0.91;阳性预测值[PPV] = 0.70)。基于mri的内侧和外侧PTS,以及PTS不对称,在两组之间没有显著差异。单因素logistic回归显示,放射学PTS每增加1°,几率增加10% (OR = 1.10, 95% CI: 1.00-1.22, p = 0.049),在调整BMI、性别、侧面、身高和体重后,几率仍然显著(调整OR = 1.11, 95% CI: 1.01-1.23, p = 0.034)。放射学内侧PTS与mri内侧PTS呈正相关(r = 0.49, p = 0.05)。结论:内侧段放射学PTS在成功的原发性ACLR和多次翻修ACLR之间表现出强烈的差异。PTS≥16°表明患者具有明显更高的多次翻修风险,而基于mri的内侧PTS、外侧PTS和PTS不对称没有额外的歧视性价值。放射医学PTS对于术前风险分层似乎是实用的,而基于mri的测量则没有显示出类似的效用。证据等级:三级。
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Journal of Experimental Orthopaedics
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