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Elevated risk of patellofemoral osteoarthritis following ACL reconstruction compared to contralateral knees: A systematic review and meta-analysis 与对侧膝关节相比,前交叉韧带重建后髌股骨关节炎的风险增加:一项系统回顾和荟萃分析。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-18 DOI: 10.1002/jeo2.70467
Domenico Franco, Alexander Bumberger, Chilan B. G. Leite, Sebastian Schmidt, Rocco Papalia, Vincenzo Denaro, Cale Jacobs, Christian Lattermann
<div> <section> <h3> Purpose</h3> <p>To investigate the development of patellofemoral osteoarthritis (PFOA) in the affected knee of anterior cruciate reconstruction (ACL-R) patients compared to their contralateral knee. The impact of graft choice on PFOA progression was also examined.</p> </section> <section> <h3> Methods</h3> <p>A systematic literature search was performed up to 1 June 2025. Studies at level of evidence II and III reporting imaging outcomes of the patellofemoral (PF) joint following ACL-R and contralateral knees were included. Studies involving isolated primary ACL-R procedures, regardless of meniscus status, were considered. The meta-analysis was performed to assess if ACL-R was associated with a higher likelihood of PFOA compared to contralateral knees. Furthermore, a sub-analysis was conducted to evaluate whether the patellar tendon autograft was associated with a higher chance of PFOA than hamstring autografts. The random effects model was used to calculate the pooled odds ratio of PFOA in patients following ACL-R compared to the control group. Meta-regression analysis was performed to determine whether sample size, follow-up duration and population age significantly influenced the odds ratio.</p> </section> <section> <h3> Results</h3> <p>Eleven studies met the inclusion criteria and were included in this review. A total of 1206 participants were included, with an average male/female ratio of 57/49 and a pooled weighted mean age of 27 years. The follow-up duration varied from 1 to 17.8 years, with an average of 5 years. Radiographic definitions of PFOA were determined using the Kellgren–Lawrence and the Osteoarthritis Research Society International (OARSI) classifications, while the magnetic resonance imaging (MRI) PFOA definition was derived from the MRI Osteoarthritis Knee Score (MOAKS) grading. Patients undergoing ACL-R demonstrated a significantly higher likelihood of PFOA compared to their contralateral knees (<i>p</i> = 0.01). The use of patellar tendon or hamstring autografts did not show significant differences.</p> </section> <section> <h3> Conclusions</h3> <p>Patients undergoing ACL-R are more likely to develop PFOA than their contralateral knees. No significant difference in risk of PFOA development was found between hamstrings tendon and patellar tendon autografts.</p> </section> <section> <h3> Level of Evidence</h3> <p>Level II and III, systematic review and meta-analysis studies.</p> </section>
目的:探讨前交叉韧带重建术(ACL-R)患者患膝髌骨股骨骨关节炎(PFOA)与对侧膝关节的发展情况。移植物选择对PFOA进展的影响也进行了研究。方法:系统检索截至2025年6月1日的文献。证据II和III级的研究报告了ACL-R和对侧膝关节后髌骨股骨(PF)关节的影像学结果。研究涉及孤立的原发性ACL-R手术,而不考虑半月板状态。进行荟萃分析以评估与对侧膝关节相比,ACL-R是否与PFOA的高可能性相关。此外,我们还进行了一项亚分析,以评估髌骨肌腱自体移植物是否比腿筋自体移植物更容易发生PFOA。采用随机效应模型计算ACL-R患者与对照组相比PFOA的合并优势比。采用meta回归分析确定样本量、随访时间和人口年龄是否显著影响比值比。结果:11项研究符合纳入标准,纳入本综述。共纳入1206名参与者,平均男女比例为57/49,合并加权平均年龄为27岁。随访时间1 ~ 17.8年,平均5年。采用kellgreen - lawrence和国际骨关节炎研究协会(OARSI)分类确定PFOA的放射学定义,而磁共振成像(MRI) PFOA的定义来自MRI骨关节炎膝关节评分(MOAKS)分级。与对侧膝关节相比,接受ACL-R的患者PFOA的可能性显著增加(p = 0.01)。髌骨肌腱或腘绳肌腱自体移植物的使用无显著差异。结论:接受ACL-R的患者比其对侧膝关节更容易发生PFOA。腘绳肌腱与髌骨肌腱自体移植在PFOA发生风险上无显著差异。证据等级:二级和三级,系统评价和荟萃分析研究。
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引用次数: 0
Proximal tibiofibular joint dislocation is rare in knee dislocations type Schenck III or higher 近端胫腓关节脱位在Schenck III型或更高级别的膝关节脱位中是罕见的。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-18 DOI: 10.1002/jeo2.70556
Ben Louis Wagener, Timo Stausberg, Bertil Bouillon, Thomas Rudolf Pfeiffer, Thomas Stein, Daniel Guenther

Purpose

The purpose of the study was to determine the prevalence of proximal tibiofibular joint (PTFJ) dislocations in knee dislocations classified as Schenck type ≥III and to compare with uninjured contralateral knees, which served as control cohort.

Methods

Patients treated at Cologne Merheim Medical Center with knee dislocation ≥III between 2015 and 2022 were included, while one control group consisted of uninjured contralateral knees. In addition to established PTFJ-specific parameters, two novel computed tomography-based PTFJ parameters were implemented on scans obtained a mean of 5 days post-trauma. The fibula lateralisation quantifies the lateral shift of the proximal fibula joint line in relation to the tibial PTFJ joint line. The posterior fibula area quantifies the fibula position in the sagittal plane with reference to the posterior tibial margin.

Results

A total of 107 knee joints were included, comprising 40 with knee dislocation ≥III, 24 uninjured contralateral knees and 43 chronically isolated anterior cruciate ligament insufficient knees. The overall cohort had a median posterior fibula area of 92.7% and a fibula lateralisation of 0.0%. Complete PTFJ dislocation was observed in 5.4% of knee dislocation cases, all in type IV injuries. Fibula lateralisation analysis indicated PTFJ subluxation in an additional 21.6% of cases. No PTFJ dislocations were present in the contralateral knee group. The knee dislocation group differed significantly from the matched contralateral knee group with regard to fibula lateralisation (r = 0.43; p = 0.007), whereas no differences were observed for inclination-horizontal (p = 0.620), inclination-fibular axis (p = 0.082) and obliquity (p = 0.602).

Conclusions

This study demonstrates a 5.4% prevalence of PTFJ dislocation in knee dislocations ≥III, which is lower than previously reported. The incidence of PTFJ dislocation in knee dislocations type IV is high at 33.3%. Fibula lateralisation and posterior fibula area are suitable parameters for assessing anterolateral dislocation of the proximal fibula. Inclination-horizontal, inclination-fibular axis and obliquity show no relevant side-to-side differences in individuals.

Level of Evidence

Level III.

目的:本研究旨在确定Schenck≥III型膝关节脱位中近端胫腓关节(PTFJ)脱位的发生率,并与未损伤的对侧膝关节作为对照队列进行比较。方法:选取2015 - 2022年在科隆梅尔海姆医疗中心治疗的≥III型膝关节脱位患者为研究对象,另设对侧未损伤膝关节为对照组。除了已建立的PTFJ特异性参数外,在创伤后平均5天的扫描中实现了两个新的基于计算机断层扫描的PTFJ参数。腓骨侧化量化了腓骨近端关节线相对于胫骨PTFJ关节线的侧移。腓骨后区以胫骨后缘为参照,量化了腓骨在矢状面上的位置。结果:共纳入107个膝关节,其中膝关节脱位≥III级40个,对侧未损伤膝关节24个,慢性孤立前交叉韧带不足膝关节43个。整个队列的腓骨后中位面积为92.7%,腓骨外侧化为0.0%。5.4%的膝关节脱位病例发生完全性PTFJ脱位,均为IV型损伤。腓骨侧位分析显示另外21.6%的病例PTFJ半脱位。对侧膝关节组无PTFJ脱位。膝关节脱位组与匹配的对侧膝关节组在腓骨侧化方面差异显著(r = 0.43; p = 0.007),而在倾斜-水平(p = 0.620)、倾斜-腓骨轴(p = 0.082)和倾斜(p = 0.602)方面没有观察到差异。结论:本研究表明,≥III型膝关节脱位中PTFJ脱位的发生率为5.4%,低于之前的报道。IV型膝关节脱位中PTFJ脱位的发生率较高,为33.3%。腓骨外侧和腓骨后面积是评估腓骨近端前外侧脱位的合适参数。倾斜度-水平、倾斜度-腓骨轴和倾斜度在个体中没有相关的侧对侧差异。证据等级:三级。
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引用次数: 0
Low graft failure and favourable outcomes after anterior cruciate ligament reconstruction and lateral extra-articular tenodesis in young athletes 年轻运动员前交叉韧带重建和外侧关节外肌腱固定术后移植物失败率低,预后良好。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-16 DOI: 10.1002/jeo2.70524
Mihail Lazar Mioc, Blaithin Brady, Anna Rose O'Brien, Mihai Vioreanu

Purpose

Young athletes undergoing anterior cruciate ligament reconstruction (ACLR) are at high risk of graft failure and contralateral anterior cruciate ligament (CACL) injury, despite advances in surgical technique. Lateral extra-articular tenodesis (LET) has emerged as a potential adjunct to improve graft survivability in high-risk young populations. The study aimed to describe graft survival, CACL rates, patient-reported outcome measures (PROMs) and return-to-sport (RTS) outcomes in high-risk under-20 athletes undergoing ACLR and LET.

Methods

This retrospective cohort study analysed U20 athletes who underwent primary ACLR with hamstring tendon autografts and concurrent LET between 2017 and 2023. All surgeries were performed by a single surgeon using a standardized technique. Outcomes included graft survivability, CACL injury incidence, and RTS level, with functional recovery assessed via the Marx Activity Scale and Tegner–Lysholm Score. Kaplan–Meier survival analysis, independent t-tests, χ2 tests, and multivariate logistic regression were used to evaluate outcomes and identify predictors, with significance set at p < 0.05.

Results

One hundred fifty-nine patients (mean age 17.6 ± 1.9 years) were included, with a mean follow-up of 49.7 ± 18.8 months. Graft rerupture occurred in 2.5% of patients, all within 40 months postoperatively. CACL injury was observed in 12.6% of patients. Over 60% of athletes returned to their pre-injury level of sport, with higher PROMs in those achieving same-level RTS. A smaller graft diameter was significantly associated with increased risk of CACL injury (p < 0.05). LET was not associated with adverse effects on functional recovery.

Conclusions

This cohort showed low graft rerupture rates, favourable functional outcomes and encouraging RTS levels following ACLR and LET. However, CACL injury remained a substantial concern. LET may be considered in adolescent athletes participating in pivoting sports to potentially reduce graft failure, although further comparative studies are needed.

Level of Evidence

Level IV.

目的:尽管手术技术有所进步,但接受前交叉韧带重建(ACLR)的年轻运动员移植物失败和对侧前交叉韧带(CACL)损伤的风险很高。外侧关节外肌腱固定术(LET)已成为提高高危年轻人群移植物存活率的潜在辅助手段。该研究旨在描述接受ACLR和LET的高风险20岁以下运动员的移植物存活、CACL率、患者报告的结果测量(PROMs)和重返运动(RTS)结果。方法:本回顾性队列研究分析了U20运动员在2017年至2023年间接受原发性ACLR合并腘绳肌腱自体移植和并发LET的患者。所有手术均由一名外科医生使用标准化技术进行。结果包括移植物存活率、CACL损伤发生率和RTS水平,并通过Marx活动量表和Tegner-Lysholm评分评估功能恢复。采用Kaplan-Meier生存分析、独立t检验、χ 2检验和多因素logistic回归评价结局和确定预测因素,显著性设置为p。结果:纳入159例患者,平均年龄17.6±1.9岁,平均随访49.7±18.8个月。2.5%的患者发生移植物再破裂,均在术后40个月内发生。12.6%的患者发生CACL损伤。超过60%的运动员恢复到他们受伤前的运动水平,那些达到相同水平RTS的运动员有更高的prom。较小的移植物直径与CACL损伤风险增加显著相关(p结论:该队列显示,ACLR和LET后移植物再破裂率低,功能预后良好,RTS水平令人鼓舞。然而,韧带损伤仍然是一个重要的问题。尽管还需要进一步的比较研究,但青少年运动员在参加旋转运动时可能会考虑LET,以潜在地减少移植物衰竭。证据等级:四级。
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引用次数: 0
Current concept on assessment and management of anterior cruciate ligament injury in skeletally immature athletes 骨未成熟运动员前交叉韧带损伤的评估和治疗现状。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-16 DOI: 10.1002/jeo2.70498
Alberto Grassi, Kyle Borque, Claudio Rossi, Bruna Cascone, Francesco Della Villa, Stefano Zaffagnini

The incidence of anterior cruciate ligament (ACL) injuries in paediatric and skeletally immature patients is rising, proportionally to the worldwide spread of sport participation. However, differently from adults, injuries in young patients pose serious challenges regarding their management, especially when surgery is required. To date, controversies remain regarding the indications, timing of surgery and techniques for ACL reconstruction. This current concept provides a deep and detailed theoretical background of ACL injury and management in patients with open physis. Moreover, a practical algorithm of treatment is provided based on authors' experience and research and current evidence-based medicine (EBM). To optimise management and reduce the risks of either conservative or surgical treatment, a deep knowledge of the specific concepts related to paediatric patients is required.

Level of Evidence

Level V.

前交叉韧带(ACL)损伤的发生率在儿科和骨骼不成熟的患者正在上升,成比例的运动参与的全球传播。然而,与成人不同的是,年轻患者的损伤对他们的治疗提出了严峻的挑战,特别是当需要手术治疗时。迄今为止,关于前交叉韧带重建的适应症、手术时机和技术仍存在争议。目前的概念为开放性物理患者的ACL损伤和处理提供了深入而详细的理论背景。并结合作者的经验和研究,结合当前循证医学的发展趋势,提出了一种实用的治疗算法。为了优化管理和降低保守或手术治疗的风险,需要深入了解与儿科患者相关的具体概念。证据等级:V级。
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引用次数: 0
Patient-specific psychological characteristics and personality structure affect post-operative outcomes and readiness to return to sport following medial patellofemoral ligament reconstruction 患者特定的心理特征和人格结构影响手术后的结果和准备恢复运动后内侧髌股韧带重建。
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-16 DOI: 10.1002/jeo2.70472
Lisa Rahn, Andrea Achtnich, Moritz Brunner, Lukas N. Muench, Maximilian Hinz, Julian Mehl, Sebastian Siebenlist, Armin Runer
<div> <section> <h3> Purpose</h3> <p>The purpose of this study was to evaluate the influence of patient-specific psychological characteristics and personality structure on the functional outcomes and return to sports (RTS) after isolated medial patellofemoral ligament (MPFL) reconstruction for patellofemoral instability (PFI).</p> </section> <section> <h3> Methods</h3> <p>Patients who underwent isolated MPFL reconstruction for PFI between 2017 and 2020 were retrospectively included. Minimum 18 months post-operatively, patient-reported outcome measures, including the Banff Patellofemoral Instability Instrument 2.0 (BPII 2.0), visual analogue scale (VAS) for pain and function, Tegner activity scale (TAS) and Marx activity rating scale (MARS) were evaluated. The MPFL-Return to Sport after Injury (MPFL-RSI) scale was used to determine psychological readiness to RTS. Kinesiophobia was measured using the Tampa Scale of Kinesiophobia (TSK), and the tendency to catastrophize pain was measured using the pain catastrophizing scale (PCS). Self-efficacy was assessed using the General Self-Efficacy Short Scale-3 (GSE-3 scale). Personality structure was classified using a variant of the Big Five Inventory (BFI-10). The Live Orientation Test (LOT-R) was used to measure generalized optimism/pessimism. The primary outcome was the correlation between MPFL-RSI score and BPII 2.0. The data were statistically analyzed using Pearson or Spearman correlation analysis as appropriate.</p> </section> <section> <h3> Results</h3> <p>In total, 54 patients (24 ± 8 years, follow-up: 35.8 ± 12.8 months) were included. MPFL-RSI and BPII 2.0 correlated inversely with VAS for pain and function, fear of movement (TSK) and pain catastrophizing (PCS). Both the MPFL-RSI and BPII 2.0 correlated significantly with self-efficacy as well as with each other. The MPFL-RSI correlated inversely with the personality characteristic ‘neuroticism’ (BFI-10) and positively with sporting activity (MARS).</p> </section> <section> <h3> Conclusion</h3> <p>Individual psychological characteristics and personality structure significantly correlate with the functional outcome and psychological readiness to RTS after MPFL reconstruction. Increased self-efficacy, reduced pain catastrophizing and exercise phobia are associated with better post-operative knee function. Preoperative assessment and consideration of these factors may inform tailored prehabilitation.</p> </section> <section> <h3> Level of Evidence</h3>
目的:本研究的目的是评估患者特定的心理特征和人格结构对髌股不稳(PFI)孤立髌股内侧韧带(MPFL)重建后功能结局和重返运动(RTS)的影响。方法:回顾性纳入2017年至2020年间因PFI接受孤立性MPFL重建的患者。术后至少18个月,评估患者报告的预后指标,包括Banff髌股不稳定仪2.0 (BPII 2.0)、疼痛和功能视觉模拟量表(VAS)、Tegner活动量表(TAS)和Marx活动评定量表(MARS)。mpfl -损伤后重返运动(MPFL-RSI)量表用于确定RTS的心理准备程度。运动恐惧症采用坦帕运动恐惧症量表(TSK)测量,疼痛灾难化量表(PCS)测量疼痛灾难化倾向。采用一般自我效能短量表-3 (GSE-3)评估自我效能。使用大五人格量表(BFI-10)的一种变体对人格结构进行分类。采用生活取向测验(LOT-R)测量广义乐观/悲观情绪。主要观察结果为MPFL-RSI评分与BPII 2.0的相关性。采用Pearson或Spearman相关分析对数据进行统计学分析。结果:共纳入54例患者(24±8年,随访35.8±12.8个月)。MPFL-RSI和BPII 2.0与VAS在疼痛和功能、运动恐惧(TSK)和疼痛灾难(PCS)方面呈负相关。MPFL-RSI和BPII 2.0均与自我效能感显著相关。MPFL-RSI与人格特征“神经质”(BFI-10)呈负相关,与体育活动(MARS)呈正相关。结论:个体心理特征和人格结构与MPFL重建后的功能结局和RTS心理准备程度显著相关。增强的自我效能,减轻疼痛灾难和运动恐惧症与术后膝关节功能的改善有关。术前评估和考虑这些因素可以为量身定制的康复治疗提供信息。证据等级:四级。
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引用次数: 0
Arthroscopic-assisted management of talus and calcaneus fractures: A narrative review of the clinical outcomes and surgical technique 关节镜辅助治疗距骨和跟骨骨折:临床结果和手术技术的叙述性回顾
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-15 DOI: 10.1002/jeo2.70510
Hayden Hartman, Haley Tornberg, Paul Fine-Lease, Arianna L. Gianakos

While distinct in incidence and presentation, both talus and calcaneus fractures share a common challenge in their complex anatomy and high-energy mechanisms resulting in difficulties in treatment. With traditional open reduction and internal fixation (ORIF), these fractures carry a high risk of complications, such as avascular necrosis, infection and post-traumatic arthritis. New minimally invasive strategies have risen to the forefront, with arthroscopic-assisted reduction and internal fixation (ARIF) emerging as a promising alternative. This technique offers the potential for enhanced visualisation, reduced soft-tissue disruption, quicker recover and greater reduction advantage. The purpose of this narrative review was to discuss outcomes and surgical techniques of arthroscopic-assisted reduction and internal fixation (ARIF) of talus and calcaneus fractures. ARIF techniques varied in patient positioning, portal use and fixation strategies, but consistently emphasised anatomic reduction via microscopic visualisation typically with temporary Kirshner wires, followed by fixation with cannulated screws. Despite the technical learning curve, the use of ARIF demonstrated clear advantages in minimising soft-tissue trauma and enhancing joint preservation in both talus and calcaneus fractures. This review supports the growing role of minimally invasive techniques as a viable alternative to ORIF in patients with high-energy talus and calcaneus fractures.

Level of Evidence

Level IV.

尽管距骨和跟骨骨折的发生率和表现不同,但它们复杂的解剖结构和高能量机制都给治疗带来了困难。对于传统的切开复位内固定(ORIF),这些骨折有很高的并发症风险,如无血管坏死、感染和创伤后关节炎。新的微创策略已经上升到最前沿,关节镜辅助复位和内固定(ARIF)成为一种有希望的替代方法。该技术提供了增强可视化、减少软组织破坏、更快恢复和更大复位优势的潜力。这篇叙述性综述的目的是讨论关节镜辅助复位内固定治疗距骨和跟骨骨折的疗效和手术技术。ARIF技术在患者体位、门静脉使用和固定策略上各不相同,但始终强调通过显微镜观察解剖复位,通常采用临时克氏针,然后用空心螺钉固定。尽管存在技术学习曲线,但在距骨和跟骨骨折中,使用ARIF在最大限度地减少软组织损伤和增强关节保护方面显示出明显的优势。这篇综述支持微创技术在高能距骨和跟骨骨折患者中作为ORIF的可行替代方案的作用日益增强。证据等级四级。
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引用次数: 0
MCID normalization: A methodological framework for harmonizing heterogeneous PROMs in hip arthroscopy research MCID规范化:协调髋关节镜研究中异质PROMs的方法学框架
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-15 DOI: 10.1002/jeo2.70568
Nikolai Ramadanov

Hip arthroscopy (HAS) research employs a wide range of patient-reported outcome measures (PROMs). This heterogeneity complicates cross-study comparisons and meta-analyses, as no gold-standard PROM exists. The minimal clinically important difference (MCID) offers a clinically meaningful threshold of change, but methodological guidance on integrating heterogeneous PROMs through MCID has been lacking. Can heterogeneous PROMs in HAS be harmonized through MCID normalization? PROMs reported in 100 HAS studies were identified and ranked according to frequency of use. The most frequently reported MCID values from published validation studies were applied. Each PROM was then evaluated and normalized by dividing observed mean values and standard deviations by the respective MCID, thereby yielding a standardized metric expressed in ‘MCID units’. A proof-of-concept data set with seven simulated two-arm studies was created to demonstrate the stepwise process of PROM prioritization, MCID-based normalization and subsequent synthesis through random-effects meta-analysis using the restricted maximum likelihood (REML) estimator. Across the 100 included studies, 214 PROM mentions were identified, with modified Harris Hip Score (mHHS) (33.2%), International Hip Outcome Tool—12 items (iHOT-12) (16.4%) and Hip Outcome Score—Sports Subscale (HOS-SSS) (15.4%) being the most frequent. Normalization successfully transformed heterogeneous PROMs into a unified outcome scale, enabling synthesis of results as ‘number of clinically meaningful improvements’. The framework preserved clinical interpretability and allowed transparent, reproducible pooling of outcomes. A proof-of-concept data set of seven simulated studies illustrated stepwise MCID-based normalization and synthesis through random-effects meta-analysis (REML). MCID normalization may offer a robust and clinically relevant methodology to harmonize diverse PROMs in HAS research. Its application may enhance comparability, reduce bias in evidence synthesis and support meaningful interpretation of meta-analytic findings. Importantly, it translates heterogeneous PROMs into a unified, clinically interpretable metric, thereby helping clinicians and researchers to better assess treatment effectiveness across studies. This approach could also be adapted to other surgical fields with fragmented outcome reporting.

Level of Evidence

Level V, expert opinion.

髋关节镜(HAS)研究采用了广泛的患者报告的结果测量(PROMs)。这种异质性使交叉研究比较和荟萃分析变得复杂,因为不存在黄金标准的PROM。最小临床重要差异(MCID)提供了一个具有临床意义的变化阈值,但通过MCID整合异质PROMs的方法学指导一直缺乏。是否可以通过MCID规范化来协调HAS中的异构prom ?在100个HAS研究中报告的prom被确定并根据使用频率进行排名。应用已发表的验证研究中最常报道的MCID值。然后通过将观察到的平均值和标准差除以各自的MCID,对每个PROM进行评估和归一化,从而产生以“MCID单位”表示的标准化度量。创建了一个包含七个模拟双臂研究的概念验证数据集,以演示通过使用受限最大似然(REML)估计器进行随机效应meta分析,逐步确定PROM优先级,基于mcid的规范化和随后的合成过程。在纳入的100项研究中,确定了214例PROM,其中最常见的是修改Harris髋关节评分(mHHS)(33.2%),国际髋关节结局工具-12项目(iHOT-12)(16.4%)和髋关节结局评分-运动子量表(HOS-SSS)(15.4%)。标准化成功地将异质PROMs转化为统一的结果量表,使结果能够综合为“临床有意义的改善数量”。该框架保留了临床可解释性,并允许透明、可重复的结果汇总。七项模拟研究的概念验证数据集通过随机效应荟萃分析(REML)说明了逐步基于mcid的规范化和综合。MCID规范化可以提供一个强大的和临床相关的方法来协调HAS研究中的各种PROMs。它的应用可以增强可比性,减少证据合成中的偏倚,并支持对元分析结果的有意义的解释。重要的是,它将异质PROMs转化为统一的、临床可解释的指标,从而帮助临床医生和研究人员更好地评估研究中的治疗效果。这种方法也可以适用于其他手术领域,结果报告不完整。证据等级V级,专家意见。
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引用次数: 0
Femorotibial rotation does not affect clinical outcomes after patellofemoral stabilizing surgery 髌股稳定手术后,股胫旋转不影响临床结果
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-14 DOI: 10.1002/jeo2.70532
Marc Schmid, Giuseppe Loggia, Andreas Flury, Gabriele Cirigliano, Stefan Zimmermann, Lazaros Vlachopoulos, Sandro Hodel, Sandro Fucentese
<div> <section> <h3> Purpose</h3> <p>The role of femorotibial rotation in patellar instability treatment and prognosis remains unclear. This study examines whether increased femorotibial rotation, indicated by a positive winking sign, affects functional outcomes and recurrent instability after patellofemoral stabilizing surgery.</p> </section> <section> <h3> Methods</h3> <p>All patients undergoing patellofemoral instability surgery at our institution (2014–2022) with complete rotational imaging (magnetic resonance imaging/computed tomography [MRI/CT]) and functional assessments (Kujala, Tegner) and at least 1-year follow-up were included. Patients were grouped based on the presence of a radiological winking sign. Surgical treatment was tailored to individual deformities, including medial patellofemoral ligament reconstruction, trochleoplasty, derotational osteotomy and tibial tuberosity osteotomy.</p> </section> <section> <h3> Results</h3> <p>A total of 121 knees (114 patients, mean age 23.5 years) with a mean follow-up of 2 years were analyzed. Preoperatively, the winking sign was present in 19.8% (<i>n</i> = 24) and absent in 80.2% (<i>n</i> = 97). Demographics and preoperative deformity analysis were similar between groups (n.s.) except for increased femorotibial rotation (11.8° ± 7° vs. 8.5° ± 5°; <i>p</i> = 0.031) and patellar tilt (<i>p</i> = 0.006) in patients with a positive winking sign. Functional outcome scores either improved (Kujala: 68.9 ± 16 to 80.8 ± 19; <i>p</i> < 0.001) or remained unchanged (Tegner: 3.6 ± 1.4 to 3.4 ± 1.6; <i>p</i> = 0.347) from pre- to postoperative. Patients with a positive winking sign tended to show less improvement (Δ Kujala: 7.6 ± 18 vs. 13.0 ± 20; <i>p</i> = 0.170; Δ Tegner: 0.0 ± 1.7 vs. −0.1 ± 2.0; <i>p</i> = 0.373). Surgical procedures were evenly distributed between groups (n.s.). One patient (0.8%) with a negative winking sign had a recurrent instability. Complications did not differ between groups (n.s.).</p> </section> <section> <h3> Conclusion</h3> <p>Patients with increased femorotibial rotation achieve similar functional outcome following patellofemoral stabilizing surgery without increased complications or persistent instability. A tendency for less functional improvement in these patients raises questions about the need to assess femorotibial rotation as an independent deformity. Further research is needed to investigate this topic more deeply.</p> </section> <section> <h3> Level of Evidence</h3>
目的股胫旋转在髌骨不稳治疗和预后中的作用尚不清楚。本研究探讨了髌股稳定手术后增加的股胫旋转是否会影响功能结局和复发性不稳定。方法纳入2014-2022年在我院接受髌骨不稳定手术的所有患者,并进行完整的旋转成像(磁共振成像/计算机断层扫描[MRI/CT])和功能评估(Kujala, Tegner),并进行至少1年的随访。根据有无放射学上的眨眼迹象对患者进行分组。手术治疗针对个体畸形,包括内侧髌股韧带重建、滑车成形术、旋转截骨术和胫骨结节截骨术。结果共分析121个膝关节(114例,平均23.5岁),平均随访2年。术前有眨眼征的占19.8% (n = 24),无眨眼征的占80.2% (n = 97)。两组之间的人口统计学和术前畸形分析相似(n.s),除了阳性眨眼体征患者的股胫旋转增加(11.8°±7°vs. 8.5°±5°;p = 0.031)和髌骨倾斜(p = 0.006)。功能结局评分从术前到术后改善(Kujala: 68.9±16至80.8±19;p < 0.001)或保持不变(Tegner: 3.6±1.4至3.4±1.6;p = 0.347)。眨眼征阳性的患者往往改善较少(Δ Kujala: 7.6±18 vs. 13.0±20;p = 0.170; Δ Tegner: 0.0±1.7 vs. - 0.1±2.0;p = 0.373)。手术方式组间分布均匀(n.s.)。1例(0.8%)眨眼阴性的患者有复发性不稳定。并发症在两组间无差异(注1)。结论髌股稳定手术后增加股胫旋转的患者可获得相似的功能结果,且无并发症增加或持续不稳定。这些患者功能改善较少的趋势提出了需要将股胫旋转作为独立畸形进行评估的问题。这一课题需要进一步深入研究。证据等级三级。
{"title":"Femorotibial rotation does not affect clinical outcomes after patellofemoral stabilizing surgery","authors":"Marc Schmid,&nbsp;Giuseppe Loggia,&nbsp;Andreas Flury,&nbsp;Gabriele Cirigliano,&nbsp;Stefan Zimmermann,&nbsp;Lazaros Vlachopoulos,&nbsp;Sandro Hodel,&nbsp;Sandro Fucentese","doi":"10.1002/jeo2.70532","DOIUrl":"https://doi.org/10.1002/jeo2.70532","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The role of femorotibial rotation in patellar instability treatment and prognosis remains unclear. This study examines whether increased femorotibial rotation, indicated by a positive winking sign, affects functional outcomes and recurrent instability after patellofemoral stabilizing surgery.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;All patients undergoing patellofemoral instability surgery at our institution (2014–2022) with complete rotational imaging (magnetic resonance imaging/computed tomography [MRI/CT]) and functional assessments (Kujala, Tegner) and at least 1-year follow-up were included. Patients were grouped based on the presence of a radiological winking sign. Surgical treatment was tailored to individual deformities, including medial patellofemoral ligament reconstruction, trochleoplasty, derotational osteotomy and tibial tuberosity osteotomy.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 121 knees (114 patients, mean age 23.5 years) with a mean follow-up of 2 years were analyzed. Preoperatively, the winking sign was present in 19.8% (&lt;i&gt;n&lt;/i&gt; = 24) and absent in 80.2% (&lt;i&gt;n&lt;/i&gt; = 97). Demographics and preoperative deformity analysis were similar between groups (n.s.) except for increased femorotibial rotation (11.8° ± 7° vs. 8.5° ± 5°; &lt;i&gt;p&lt;/i&gt; = 0.031) and patellar tilt (&lt;i&gt;p&lt;/i&gt; = 0.006) in patients with a positive winking sign. Functional outcome scores either improved (Kujala: 68.9 ± 16 to 80.8 ± 19; &lt;i&gt;p&lt;/i&gt; &lt; 0.001) or remained unchanged (Tegner: 3.6 ± 1.4 to 3.4 ± 1.6; &lt;i&gt;p&lt;/i&gt; = 0.347) from pre- to postoperative. Patients with a positive winking sign tended to show less improvement (Δ Kujala: 7.6 ± 18 vs. 13.0 ± 20; &lt;i&gt;p&lt;/i&gt; = 0.170; Δ Tegner: 0.0 ± 1.7 vs. −0.1 ± 2.0; &lt;i&gt;p&lt;/i&gt; = 0.373). Surgical procedures were evenly distributed between groups (n.s.). One patient (0.8%) with a negative winking sign had a recurrent instability. Complications did not differ between groups (n.s.).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Patients with increased femorotibial rotation achieve similar functional outcome following patellofemoral stabilizing surgery without increased complications or persistent instability. A tendency for less functional improvement in these patients raises questions about the need to assess femorotibial rotation as an independent deformity. Further research is needed to investigate this topic more deeply.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Level of Evidence&lt;/h3&gt;\u0000 \u0000 ","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"12 4","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://esskajournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jeo2.70532","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of time-dependent changes in the subchondral bone density distribution of the proximal tibia following high tibial osteotomy 胫骨高位截骨后胫骨近端软骨下骨密度分布随时间变化的特征
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-14 DOI: 10.1002/jeo2.70517
Yoshiaki Hosokawa, Koji Iwasaki, Taku Ebata, Dai Sato, Masanari Hamasaki, Masatake Matsuoka, Tomohiro Onodera, Eiji Kondo, Norimasa Iwasaki

Purpose

This study aimed to evaluate the time-dependent changes in the medial and lateral subchondral bone density distribution of the tibial joint surface before and after high tibial osteotomy (HTO) using computed tomography-osteoabsorptiometry.

Methods

This study included 17 patients (20 knees) (8 men and 9 women; mean age: 55 years) who underwent HTO for medial compartment osteoarthritis. Computed tomography-osteoabsorptiometry was conducted to measure the subchondral bone density distribution in the tibial joint surface. The high-density area (HDA), defined as the region corresponding to the highest Hounsfield unit values that comprises 20% of the total region, was calculated. Medial ratio was defined as the proportion of the HDA in the medial compartment relative to the total HDA of both compartments. Measurements were performed preoperatively and at 3, 6, 12 and 24 months post-operatively, and a generalized linear regression analysis with a gamma distribution model was conducted.

Results

The medial ratios (mean ± standard deviation) were 89 ± 9% preoperatively, 73 ± 12% at 3 months, 78 ± 13% at 6 months, 78 ± 10% at 12 months and 77 ± 17% at 24 months. Based on the gamma distribution, the non-linear model was expressed as follows: Y = 82.8 × t0.04 × exp(−0.004 × t). This finding indicated that the medial ratio had a decreasing trend, reaching its minimum at 10.2 months post-operatively.

Conclusion

This study showed time-dependent changes in the subchondral bone density on the tibial side after HTO. The changes in the bone density distribution on the medial and lateral tibial joint surface, which are associated with alignment correction, stabilized at approximately 10.5 months post-operatively. Therefore, the optimal timing for evaluating subchondral bone density in response to stress redistribution may be after 10.2 months.

Level of Evidence

Level IV.

目的利用计算机断层扫描-骨吸收术评估胫骨高位截骨术前后胫骨关节面内侧和外侧软骨下骨密度分布的时间依赖性变化。方法本研究纳入17例(20个膝关节)患者(8男9女,平均年龄55岁),因内侧筋膜室骨关节炎行HTO治疗。采用计算机断层扫描-骨吸收仪测量胫骨关节面软骨下骨密度分布。计算高密度区域(HDA),定义为Hounsfield单位值最高的区域,占总区域的20%。内侧比定义为内侧室的HDA相对于两个室的总HDA的比例。分别于术前、术后3、6、12、24个月进行测量,采用广义线性回归分析伽玛分布模型。结果中位数比值(平均值±标准差)术前为89±9%,3个月时为73±12%,6个月时为78±13%,12个月时为78±10%,24个月时为77±17%。基于gamma分布,非线性模型表示为:Y = 82.8 × t - 0.04 × exp(- 0.004 × t)。这一发现表明内侧比值呈下降趋势,在术后10.2个月达到最低点。结论HTO术后胫骨侧软骨下骨密度随时间变化。胫骨内侧和外侧关节面骨密度分布的变化在术后10.5个月左右稳定下来。因此,评估软骨下骨密度对应力再分布的反应的最佳时机可能是在10.2个月后。证据等级四级。
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引用次数: 0
Predictor of clinical and functional outcomes in ankle arthroscopic ligament repair with ‘all-inside’ technique “全内”技术在踝关节镜下韧带修复中的临床和功能预后预测因子
IF 2.7 Q2 ORTHOPEDICS Pub Date : 2025-11-14 DOI: 10.1002/jeo2.70464
Fabrizio Forconi, Giorgio Fravolini, Chiara Muci, Maria Rosaria Matrangolo, Matteo Turchetta, Marianna Citro, Giulio Maccauro, Raffaele Vitiello

Purpose

Chronic ankle instability (CAI) is a common condition characterized by recurrent episodes of lateral instability, often due to a lesion of the ankle collateral lateral ligament complex. If untreated, CAI can lead to persistent symptoms and long-term degenerative changes. Arthroscopic ‘all-inside’ repair has gained traction as a minimally invasive technique offering functional and clinical benefits.

Methods

This retrospective study analyzed 43 patients undergoing arthroscopic ligament repair using the all-inside technique between 2021 and 2024. Functional outcomes were evaluated preoperatively (T0), post-rehabilitation (T1), and at the final follow-up (T2) using the Foot and Ankle Ability Measure (FAAM) score, VAS, and satisfaction ratings. Complications occurred were recorded during the follow up. Subgroup analyses investigated the influence of BMI, anchor use, and preoperative functional scores on outcomes.

Results

Patients demonstrated significant improvement in FAAM scores (T0: 71%, T2: 95%) and pain reduction (VAS: T0: 7.67, T2: 1.00). Two-anchor repairs yielded superior outcomes compared to single-anchor procedures (p = 0.01). While higher BMI was associated with poorer outcomes (p = 0.04), internal bracing improved functional scores in this subgroup. Preoperative FAAM scores did not predict postoperative outcomes (p = 0.21).

Conclusion

All-inside arthroscopic ligament repair is a safe and effective option for CAI, providing rapid recovery, low complication rates, and excellent patient satisfaction.

Level of Evidence

Level IV.

慢性踝关节不稳定(CAI)是一种常见的疾病,其特征是反复发作的外侧不稳定,通常是由于踝关节副外侧韧带复合体的病变。如果不治疗,CAI可导致持续症状和长期退行性改变。关节镜“全内”修复作为一种具有功能和临床优势的微创技术已经获得了广泛的应用。方法回顾性分析2021 - 2024年间43例关节镜下全内韧带修复术患者。术前(T0)、康复后(T1)和最终随访时(T2)采用足踝能力测量(FAAM)评分、VAS评分和满意度评分评估功能结局。随访期间记录并发症发生情况。亚组分析调查了BMI、锚的使用和术前功能评分对结果的影响。结果患者FAAM评分显著改善(T0: 71%, T2: 95%),疼痛减轻(VAS: T0: 7.67, T2: 1.00)。双锚修复比单锚修复效果更好(p = 0.01)。虽然较高的BMI与较差的预后相关(p = 0.04),但内支具改善了该亚组的功能评分。术前FAAM评分不能预测术后预后(p = 0.21)。结论关节镜下全内韧带修复术是治疗CAI安全有效的选择,恢复快,并发症发生率低,患者满意度高。证据等级四级。
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引用次数: 0
期刊
Journal of Experimental Orthopaedics
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