{"title":"Superior vena CAVA Isolation by Cryoballoon in Addition to Pulmonary Vein Isolation in Atrial Fibrillation Ablation Patients. A Randomized Trial. CAVAC AF Trial. Study Rationale and Design","authors":"Castro Victor","doi":"10.4022/jafib.20200510","DOIUrl":"https://doi.org/10.4022/jafib.20200510","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133902270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Intra-box Ablation during Posterior Wall Isolation for Persistent Atrial Fibrillation and Posterior Wall Reconnection","authors":"Tokioka Sayuri","doi":"10.4022/jafib.20200442","DOIUrl":"https://doi.org/10.4022/jafib.20200442","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131533081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Brain Natriuretic Peptide Level Predicts The Prevalence of Low-Voltage Areas and Poor Rhythm Outcome in Patients Undergoing Atrial Fibrillation Ablation","authors":"Oraii Alireza","doi":"10.4022/jafib.20200536","DOIUrl":"https://doi.org/10.4022/jafib.20200536","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130589675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Brain Natriuretic Peptide Level Predicts The Prevalence of Low-Voltage Areas and Poor Rhythm Outcome in Patients Undergoing Atrial Fibrillation Ablation","authors":"Ulus Taner","doi":"10.4022/jafib.20200519","DOIUrl":"https://doi.org/10.4022/jafib.20200519","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"18 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130798643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Association Between Physical Activity and Atrial Fibrillation: A Systematic Review of Meta-Analyses","authors":"Müssigbrodt Andreas","doi":"10.4022/jafib.20200465","DOIUrl":"https://doi.org/10.4022/jafib.20200465","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127842058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usefulness of 3D Mapping in Catheter Ablation of Residual AF Driver Showing Fibrillatory Activation in Isolated SVC","authors":"Iijima Kenichi","doi":"10.4022/jafib.20200507","DOIUrl":"https://doi.org/10.4022/jafib.20200507","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124101475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Brain Natriuretic Peptide Level Predicts The Prevalence of Low-Voltage Areas and Poor Rhythm Outcome in Patients Undergoing Atrial Fibrillation Ablation","authors":"Haywood Guy","doi":"10.4022/jafib.20200524","DOIUrl":"https://doi.org/10.4022/jafib.20200524","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123540062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electrical Isolation Following Thoracoscopic Left Atrial Appendage Exclusion During Hybrid Ablation for Longstanding Persistent Atrial Fibrillation","authors":"Bisleri Gianluigi","doi":"10.4022/jafib.20200514","DOIUrl":"https://doi.org/10.4022/jafib.20200514","url":null,"abstract":"","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"12 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123650586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-04DOI: 10.22541/au.163858750.00925195/v1
Justin Haloot, M. Mahmoud, A. Badin
Introduction: Liraglutide, a glucagon-like peptide 1 receptor agonist (GLP-1) utilized for management of type 2 diabetes mellitus, has been associated with reduced risk of cardiovascular events. However, it is also associated with increased heart rate and reduced heart rate variability. In this study, we investigate the effect of liraglutide in patients with atrial fibrillation (AF). Methods: TriNetX global research network provided aggregate data for this retrospective cohort study of AF patients on liraglutide that were matched to AF patients not on liraglutide from January 1, 2016, through November 13, 2021. Primary outcomes were all-cause mortality, ischemic stroke, hemorrhagic stroke, acute heart failure episode, and acute coronary syndrome episode. Results: 16,214 AF patients on liraglutide were propensity score matched to AF patients not on liraglutide. They were matched for demographics, cardiovascular procedures, cardiovascular medications, hypertension, diabetes, heart failure, ischemic heart disease, and diabetic medications. AF patients on liraglutide were found to have a significantly lower risk of all-cause mortality (HR 0.67, 95% CI 0.631 – 0.711, p < 0.001). There was a tendency toward lower risk of stroke, acute heart failure, and acute coronary syndrome but was not statistically significant. Conclusion: Liraglutide is associated with lower risk of all-cause mortality in AF patients. These findings are limited due to the retrospective nature of the study. Further examination is needed of liraglutide effect on mortality in AF patients.
利拉鲁肽是一种胰高血糖素样肽1受体激动剂(GLP-1)，用于治疗2型糖尿病，可降低心血管事件的风险。然而，它也与心率增加和心率变异性降低有关。在这项研究中，我们探讨利拉鲁肽在房颤(AF)患者中的作用。方法:TriNetX全球研究网络为2016年1月1日至2021年11月13日期间接受利拉鲁肽治疗的房颤患者与未接受利拉鲁肽治疗的房颤患者的回顾性队列研究提供了汇总数据。主要结局是全因死亡率、缺血性卒中、出血性卒中、急性心力衰竭发作和急性冠状动脉综合征发作。结果:16214例接受利拉鲁肽治疗的房颤患者倾向评分与未接受利拉鲁肽治疗的房颤患者相匹配。他们在人口统计学、心血管手术、心血管药物、高血压、糖尿病、心力衰竭、缺血性心脏病和糖尿病药物方面进行了匹配。利拉鲁肽组房颤患者全因死亡风险显著降低(HR 0.67, 95% CI 0.631 - 0.711, p < 0.001)。中风、急性心力衰竭和急性冠状动脉综合征的风险有降低的趋势，但没有统计学意义。结论:利拉鲁肽与房颤患者全因死亡风险降低相关。由于研究是回顾性的，这些发现是有限的。利拉鲁肽对房颤患者死亡率的影响有待进一步研究。
{"title":"Liraglutide Mortality Effect on Atrial Fibrillation Patients","authors":"Justin Haloot, M. Mahmoud, A. Badin","doi":"10.22541/au.163858750.00925195/v1","DOIUrl":"https://doi.org/10.22541/au.163858750.00925195/v1","url":null,"abstract":"Introduction: Liraglutide, a glucagon-like peptide 1 receptor agonist\u0000(GLP-1) utilized for management of type 2 diabetes mellitus, has been\u0000associated with reduced risk of cardiovascular events. However, it is\u0000also associated with increased heart rate and reduced heart rate\u0000variability. In this study, we investigate the effect of liraglutide in\u0000patients with atrial fibrillation (AF). Methods: TriNetX global research\u0000network provided aggregate data for this retrospective cohort study of\u0000AF patients on liraglutide that were matched to AF patients not on\u0000liraglutide from January 1, 2016, through November 13, 2021. Primary\u0000outcomes were all-cause mortality, ischemic stroke, hemorrhagic stroke,\u0000acute heart failure episode, and acute coronary syndrome episode.\u0000Results: 16,214 AF patients on liraglutide were propensity score matched\u0000to AF patients not on liraglutide. They were matched for demographics,\u0000cardiovascular procedures, cardiovascular medications, hypertension,\u0000diabetes, heart failure, ischemic heart disease, and diabetic\u0000medications. AF patients on liraglutide were found to have a\u0000significantly lower risk of all-cause mortality (HR 0.67, 95% CI 0.631\u0000– 0.711, p < 0.001). There was a tendency toward lower risk\u0000of stroke, acute heart failure, and acute coronary syndrome but was not\u0000statistically significant. Conclusion: Liraglutide is associated with\u0000lower risk of all-cause mortality in AF patients. These findings are\u0000limited due to the retrospective nature of the study. Further\u0000examination is needed of liraglutide effect on mortality in AF patients.","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125026160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-25DOI: 10.22541/au.163256940.04888608/v1
I. Marai, Wiaam Khatib, L. Grosman-Rimon, S. Carasso, Ali Sakhnini, E. Birati, E. Kachel
Background: Atrial fibrillation (AF) following cardiac surgery is common and has clinical impact on morbidity. The preoperative and intraoperative risk factors are still not well defined. The objective of the study was to examine preoperative and intraoperative risk factors for AF following cardiac surgery. Methods: A retrospective analysis of a database of cardiac surgeries was performed during 2017-2019 at Poriya Medical Center. Preoperative factors and intraoperative were recorded. Results: 208 patients were included in this analysis. Overall AF following cardiac surgery was detected in 50 (24%) patients. Of 175 patients who did not have history of AF prior to surgery, 27 (15.5%) had post-operative AF. In the 33 patients with previous AF, AF following surgery was detected in 23 (70%). Patients with AF following surgery who were older (66.2±8.0 vs. 60.7± 11.4 years, p=0.002), were treated more with anti-arrhythmic drugs (18.9% vs 4.5, p<0.001), and had higher rates of pre-operative AF (46% vs 6.3%, p=0.0001), prior cerebral vascular accidents (14% vs 4.4%, p=0.019), and prior valve replacement (10% vs 1.9%, p=0.009) compared to patients without AF following surgery. In multivariate Cox regression analysis, age (HR 1.04, CI 1.01-1.07, P=0.006) and history of preoperative AF (HR 6.01, CI 3.42-10.57, P<0.001) were predictors of AF following cardiac surgery. The probability of being free of postsurgical AF was 80% among patients without history of AF compared to 30% in patients with previous AF history (p<0.001). Conclusion: Preoperative AF and age were predictors of AF following cardiac surgery
背景:心脏手术后心房颤动(AF)很常见，并对其发病率有临床影响。术前和术中危险因素仍不明确。本研究的目的是检查心脏手术后房颤的术前和术中危险因素。方法:回顾性分析2017-2019年普里亚医疗中心心脏手术数据库。记录术前因素及术中情况。结果:208例患者纳入本分析。总体而言，50例(24%)患者检测到心脏手术。175例术前无房颤病史的患者中，27例(15.5%)术后发生房颤。在33例既往房颤患者中，23例(70%)术后发现房颤。年龄较大(66.2±8.0岁vs 60.7±11.4岁，p=0.002)的房颤患者使用抗心律失常药物较多(18.9% vs 4.5, p<0.001)，术前房颤发生率(46% vs 6.3%， p=0.0001)、脑血管意外发生率(14% vs 4.4%， p=0.019)和既往瓣膜置换术发生率(10% vs 1.9%， p=0.009)高于未术后患者。在多因素Cox回归分析中，年龄(HR1.04, CI 1.01-1.07, P=0.006)和术前房颤史(HR 6.01, CI3.42-10.57, P<0.001)是心脏手术后房颤的预测因素。无房颤病史的患者术后无房颤的概率为80%，有房颤病史的患者为30% (p<0.001)。结论:术前房颤和年龄是心脏手术后房颤的预测因素
{"title":"Risk Factors for Atrial Fibrillation following a Cardiac Surgery","authors":"I. Marai, Wiaam Khatib, L. Grosman-Rimon, S. Carasso, Ali Sakhnini, E. Birati, E. Kachel","doi":"10.22541/au.163256940.04888608/v1","DOIUrl":"https://doi.org/10.22541/au.163256940.04888608/v1","url":null,"abstract":"Background: Atrial fibrillation (AF) following cardiac surgery is common\u0000and has clinical impact on morbidity. The preoperative and\u0000intraoperative risk factors are still not well defined. The objective of\u0000the study was to examine preoperative and intraoperative risk factors\u0000for AF following cardiac surgery. Methods: A retrospective analysis of a\u0000database of cardiac surgeries was performed during 2017-2019 at Poriya\u0000Medical Center. Preoperative factors and intraoperative were recorded.\u0000Results: 208 patients were included in this analysis. Overall AF\u0000following cardiac surgery was detected in 50 (24%) patients. Of 175\u0000patients who did not have history of AF prior to surgery, 27 (15.5%)\u0000had post-operative AF. In the 33 patients with previous AF, AF following\u0000surgery was detected in 23 (70%). Patients with AF following surgery\u0000who were older (66.2±8.0 vs. 60.7± 11.4 years, p=0.002), were treated\u0000more with anti-arrhythmic drugs (18.9% vs 4.5, p<0.001), and\u0000had higher rates of pre-operative AF (46% vs 6.3%, p=0.0001), prior\u0000cerebral vascular accidents (14% vs 4.4%, p=0.019), and prior valve\u0000replacement (10% vs 1.9%, p=0.009) compared to patients without AF\u0000following surgery. In multivariate Cox regression analysis, age (HR\u00001.04, CI 1.01-1.07, P=0.006) and history of preoperative AF (HR 6.01, CI\u00003.42-10.57, P<0.001) were predictors of AF following cardiac\u0000surgery. The probability of being free of postsurgical AF was 80% among\u0000patients without history of AF compared to 30% in patients with\u0000previous AF history (p<0.001). Conclusion: Preoperative AF and\u0000age were predictors of AF following cardiac surgery","PeriodicalId":370568,"journal":{"name":"Journal of Atrial Fibrillation and Electrophysiology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128858595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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