Pub Date : 2025-12-11DOI: 10.1016/j.xocr.2025.100718
Umair Hafeez , Niall James McInerney , Sri Ganesh Kalimuthu , Olena Tkachuk
Lymphoepithelial carcinoma (LEC) of the salivary glands is a rare and aggressive malignancy strongly associated with Epstein–Barr virus (EBV) infection and more frequently reported in endemic regions such as Greenland and Southeast Asia. Bilateral involvement is exceptionally uncommon, particularly in non-endemic populations. We report the case of a 62-year-old male with bilateral, asymptomatic parotid swellings persisting for five years. Initial clinical assessment suggested a benign etiology, with no pain, facial nerve involvement, or other red flag symptoms. However, ultrasound, fine needle aspiration, and contrast-enhanced computed tomography of the left parotid revealed atypical features suspicious for malignancy, and histopathology confirmed LEC. The patient underwent left superficial parotidectomy with clear margins, followed by right superficial parotidectomy, which also confirmed LEC. This case represents a rare presentation of bilateral LEC in a non-endemic region. The indolent course and absence of classic malignant features highlight the diagnostic challenges of this entity. Early multidisciplinary evaluation is essential for persistent or atypical parotid swellings, and further research is warranted into the role of EBV in tumorigenesis outside endemic areas.
{"title":"Expect the unexpected: A rare case of bilateral lymphoepithelial carcinoma of the parotid gland","authors":"Umair Hafeez , Niall James McInerney , Sri Ganesh Kalimuthu , Olena Tkachuk","doi":"10.1016/j.xocr.2025.100718","DOIUrl":"10.1016/j.xocr.2025.100718","url":null,"abstract":"<div><div>Lymphoepithelial carcinoma (LEC) of the salivary glands is a rare and aggressive malignancy strongly associated with Epstein–Barr virus (EBV) infection and more frequently reported in endemic regions such as Greenland and Southeast Asia. Bilateral involvement is exceptionally uncommon, particularly in non-endemic populations. We report the case of a 62-year-old male with bilateral, asymptomatic parotid swellings persisting for five years. Initial clinical assessment suggested a benign etiology, with no pain, facial nerve involvement, or other red flag symptoms. However, ultrasound, fine needle aspiration, and contrast-enhanced computed tomography of the left parotid revealed atypical features suspicious for malignancy, and histopathology confirmed LEC. The patient underwent left superficial parotidectomy with clear margins, followed by right superficial parotidectomy, which also confirmed LEC. This case represents a rare presentation of bilateral LEC in a non-endemic region. The indolent course and absence of classic malignant features highlight the diagnostic challenges of this entity. Early multidisciplinary evaluation is essential for persistent or atypical parotid swellings, and further research is warranted into the role of EBV in tumorigenesis outside endemic areas.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100718"},"PeriodicalIF":0.3,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-04DOI: 10.1016/j.xocr.2025.100720
Lavanya Nagappan , Yekaterina Shapiro , Luke Stanisce , Donald Solomon
Neurofibromatosis type 1 (NF1) can manifest in the head and neck in a variety of ways, most commonly presenting as solitary neurofibromas. The management of these lesions require multifaceted consideration of neurovascular involvement and airway compromise. Herein, we describe a 58-year-old male with a history of NF1 and extensive cervical neurofibromas who developed a spontaneous, expanding neck hematoma secondary to his tumors. He was initially stabilized with surgical drainage and endovascular embolization, but then subsequently represented with a second rapidly expanding neck hematoma resulting in acute respiratory distress. Failed intubation due to airway edema necessitated emergent cricothyrotomy and cardiopulmonary resuscitation. Additional embolization was performed but the patient eventually succumbed to global anoxic brain injury.
This case highlights the need for proactive multi-disciplinary management with specific attention to respiratory and hemodynamic stabilization in NF1 patients with large tumor burden. As with all neck hematomas, rapid respiratory decompensation may occur, requiring prompt recognition and early intervention. This case underscores the significance of a multidisciplinary approach involving emergency medicine, critical care, anesthesia, interventional radiology, and otolaryngology to recognize and address the potential for airway compromise in the face of a neck hematoma in patients with NF1.
{"title":"Spontaneous catastrophic cervical hemorrhage in the setting of neurofibromatosis","authors":"Lavanya Nagappan , Yekaterina Shapiro , Luke Stanisce , Donald Solomon","doi":"10.1016/j.xocr.2025.100720","DOIUrl":"10.1016/j.xocr.2025.100720","url":null,"abstract":"<div><div>Neurofibromatosis type 1 (NF1) can manifest in the head and neck in a variety of ways, most commonly presenting as solitary neurofibromas. The management of these lesions require multifaceted consideration of neurovascular involvement and airway compromise. Herein, we describe a 58-year-old male with a history of NF1 and extensive cervical neurofibromas who developed a spontaneous, expanding neck hematoma secondary to his tumors. He was initially stabilized with surgical drainage and endovascular embolization, but then subsequently represented with a second rapidly expanding neck hematoma resulting in acute respiratory distress. Failed intubation due to airway edema necessitated emergent cricothyrotomy and cardiopulmonary resuscitation. Additional embolization was performed but the patient eventually succumbed to global anoxic brain injury.</div><div>This case highlights the need for proactive multi-disciplinary management with specific attention to respiratory and hemodynamic stabilization in NF1 patients with large tumor burden. As with all neck hematomas, rapid respiratory decompensation may occur, requiring prompt recognition and early intervention. This case underscores the significance of a multidisciplinary approach involving emergency medicine, critical care, anesthesia, interventional radiology, and otolaryngology to recognize and address the potential for airway compromise in the face of a neck hematoma in patients with NF1.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100720"},"PeriodicalIF":0.3,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-29DOI: 10.1016/j.xocr.2025.100717
Abdullah Almutairi , Ghadah Alotaibi , Alwaleed Alqahtani , Mohammed Almutairi , Essa Bakry
Foreign bodies in the ear, nose, and throat are common presentations that may carry a significant risk of complications. Middle ear foreign bodies are less frequently encountered and are most often associated with direct tympanic membrane perforation or iatrogenic causes, such as displaced tympanostomy tubes. In this report, we describe a case of a long-standing graphite pencil tip found within the middle ear, with a possible migration route through the Eustachian tube. This case highlights an unusual mechanism of entry and underscores the importance of careful evaluation in patients with chronic otologic symptoms.
{"title":"Neglected middle ear foreign body with unusual eustachian tube migration; case report","authors":"Abdullah Almutairi , Ghadah Alotaibi , Alwaleed Alqahtani , Mohammed Almutairi , Essa Bakry","doi":"10.1016/j.xocr.2025.100717","DOIUrl":"10.1016/j.xocr.2025.100717","url":null,"abstract":"<div><div>Foreign bodies in the ear, nose, and throat are common presentations that may carry a significant risk of complications. Middle ear foreign bodies are less frequently encountered and are most often associated with direct tympanic membrane perforation or iatrogenic causes, such as displaced tympanostomy tubes. In this report, we describe a case of a long-standing graphite pencil tip found within the middle ear, with a possible migration route through the Eustachian tube. This case highlights an unusual mechanism of entry and underscores the importance of careful evaluation in patients with chronic otologic symptoms.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100717"},"PeriodicalIF":0.3,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145681645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-19DOI: 10.1016/j.xocr.2025.100711
Michael G. Hahn , Courtney J. Hunter , André M. Wineland
Introduction
Parapharyngeal ganglioneuromas are exceedingly rare, benign tumors of the sympathetic nervous system, with fewer than 40 reported cases in this specific anatomical space over four decades. They frequently remain asymptomatic until they reach a significant size, an their rarity contributes to a limited understanding of optimal management strategies.
Case presentation
In this case report, a 16-year-old female presented with an incidental finding of a 5.2 × 3.9 × 2.0 cm right parapharyngeal space mass on a CT head. Further diagnostic imaging included a contrast-enhanced CT neck and an MRI neck. Flexible fiberoptic laryngoscopy was performed to confirm mass effect of the right lateral pharyngeal wall. Surgical excisional biopsy via an endoscope-assisted transoral approach resulted in subtotal resection due to proximity to the internal carotid artery. Pathology confirmed a benign mature ganglioneuroma (5.0 cm), positive for S100. She has been monitored with serial MRI imaging with evidence of known residual lesion and surrounding fibrosis.
Conclusion
This case highlights the rare presentation and diagnostic challenges of parapharyngeal ganglioneuromas. Achieving complete surgical resection can be complex due to tumor adherence and proximity to vital structures. Comprehensive diagnostic workup, surgical excision, and regular surveillance remain crucial for optimizing outcomes in these benign yet challenging tumors.
{"title":"Incidental parapharyngeal ganglioneuroma: A case report on surgical management","authors":"Michael G. Hahn , Courtney J. Hunter , André M. Wineland","doi":"10.1016/j.xocr.2025.100711","DOIUrl":"10.1016/j.xocr.2025.100711","url":null,"abstract":"<div><h3>Introduction</h3><div>Parapharyngeal ganglioneuromas are exceedingly rare, benign tumors of the sympathetic nervous system, with fewer than 40 reported cases in this specific anatomical space over four decades. They frequently remain asymptomatic until they reach a significant size, an their rarity contributes to a limited understanding of optimal management strategies.</div></div><div><h3>Case presentation</h3><div>In this case report, a 16-year-old female presented with an incidental finding of a 5.2 × 3.9 × 2.0 cm right parapharyngeal space mass on a CT head. Further diagnostic imaging included a contrast-enhanced CT neck and an MRI neck. Flexible fiberoptic laryngoscopy was performed to confirm mass effect of the right lateral pharyngeal wall. Surgical excisional biopsy via an endoscope-assisted transoral approach resulted in subtotal resection due to proximity to the internal carotid artery. Pathology confirmed a benign mature ganglioneuroma (5.0 cm), positive for S100. She has been monitored with serial MRI imaging with evidence of known residual lesion and surrounding fibrosis.</div></div><div><h3>Conclusion</h3><div>This case highlights the rare presentation and diagnostic challenges of parapharyngeal ganglioneuromas. Achieving complete surgical resection can be complex due to tumor adherence and proximity to vital structures. Comprehensive diagnostic workup, surgical excision, and regular surveillance remain crucial for optimizing outcomes in these benign yet challenging tumors.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100711"},"PeriodicalIF":0.3,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-19DOI: 10.1016/j.xocr.2025.100716
Manu Gupta , Sanjeev Kumar , S. Manu Prasad , Partishtha Sharma , Harish Kumar Agarwala , Vivek Kumar Jha
Background
Cleft palate repair aims not only to achieve anatomical closure but also to restore normal velopharyngeal (VP) function essential for intelligible speech. Despite technical refinements, complications such as fistula formation, wound dehiscence, and persistent velopharyngeal insufficiency (VPI) continue to affect surgical success and speech outcomes. The buccal fat pad (BFP) has emerged as a reliable, well-vascularized graft for intraoral reconstruction, offering potential benefits in enhancing healing and speech function.
Aim
To evaluate the effect of BFP interposition during Bardach two-flap palatoplasty on surgical healing, speech outcomes, and velopharyngeal competence in paediatric cleft palate patients.
Materials and methods
A prospective case series of 26 patients (17 males, 9 females; mean age 14 ± 2 months) with complete cleft palate underwent Bardach two-flap palatoplasty with BFP interposition between April 2022 and January 2024. Speech evaluations were performed preoperatively and at 3, 6, and 12 months postoperatively using age-appropriate perceptual assessments focusing on resonance, articulation, intelligibility, and VP competence. Postoperative complications, including fistula and donor site morbidity, were recorded. Data were analysed using SPSS v22, with significance set at p < 0.05.
Results
BFP provided a consistent, well-vascularized interpositional layer, resulting in satisfactory wound healing. Oronasal fistula occurred in 8 % and wound dehiscence in 4 % of cases. Donor site morbidity was minimal (4 %) and resolved spontaneously. Hypernasality decreased from 76 % preoperatively to 12 % at 12 months, nasal air emission from 64 % to 10 %, and articulation errors from 70 % to 14 %, while speech intelligibility improved from 42 % to 88 % (p < 0.05). Adequate VP closure increased from 23 % preoperatively to 88 % postoperatively.
Conclusion
BFP interposition during Bardach two-flap palatoplasty is a safe and effective adjunct for cleft palate repair. It enhances tissue healing, minimizes fistula formation, and significantly improves postoperative speech outcomes and velopharyngeal competence. Given its simplicity, minimal morbidity, and functional advantages, BFP-assisted palatoplasty represents a valuable technique in optimizing both structural and speech outcomes in cleft palate surgery.
{"title":"Speech outcomes following buccal fat pad interposition in palatal repair: A clinical outcome analysis","authors":"Manu Gupta , Sanjeev Kumar , S. Manu Prasad , Partishtha Sharma , Harish Kumar Agarwala , Vivek Kumar Jha","doi":"10.1016/j.xocr.2025.100716","DOIUrl":"10.1016/j.xocr.2025.100716","url":null,"abstract":"<div><h3>Background</h3><div>Cleft palate repair aims not only to achieve anatomical closure but also to restore normal velopharyngeal (VP) function essential for intelligible speech. Despite technical refinements, complications such as fistula formation, wound dehiscence, and persistent velopharyngeal insufficiency (VPI) continue to affect surgical success and speech outcomes. The buccal fat pad (BFP) has emerged as a reliable, well-vascularized graft for intraoral reconstruction, offering potential benefits in enhancing healing and speech function.</div></div><div><h3>Aim</h3><div>To evaluate the effect of BFP interposition during Bardach two-flap palatoplasty on surgical healing, speech outcomes, and velopharyngeal competence in paediatric cleft palate patients.</div></div><div><h3>Materials and methods</h3><div>A prospective case series of 26 patients (17 males, 9 females; mean age 14 ± 2 months) with complete cleft palate underwent Bardach two-flap palatoplasty with BFP interposition between April 2022 and January 2024. Speech evaluations were performed preoperatively and at 3, 6, and 12 months postoperatively using age-appropriate perceptual assessments focusing on resonance, articulation, intelligibility, and VP competence. Postoperative complications, including fistula and donor site morbidity, were recorded. Data were analysed using SPSS v22, with significance set at p < 0.05.</div></div><div><h3>Results</h3><div>BFP provided a consistent, well-vascularized interpositional layer, resulting in satisfactory wound healing. Oronasal fistula occurred in 8 % and wound dehiscence in 4 % of cases. Donor site morbidity was minimal (4 %) and resolved spontaneously. Hypernasality decreased from 76 % preoperatively to 12 % at 12 months, nasal air emission from 64 % to 10 %, and articulation errors from 70 % to 14 %, while speech intelligibility improved from 42 % to 88 % (p < 0.05). Adequate VP closure increased from 23 % preoperatively to 88 % postoperatively.</div></div><div><h3>Conclusion</h3><div>BFP interposition during Bardach two-flap palatoplasty is a safe and effective adjunct for cleft palate repair. It enhances tissue healing, minimizes fistula formation, and significantly improves postoperative speech outcomes and velopharyngeal competence. Given its simplicity, minimal morbidity, and functional advantages, BFP-assisted palatoplasty represents a valuable technique in optimizing both structural and speech outcomes in cleft palate surgery.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100716"},"PeriodicalIF":0.3,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fibromatosis colli (FC), also known as sternocleidomastoid pseudotumor of infancy, is a rare benign proliferation of fibrous tissue within the sternocleidomastoid muscle. It typically presents as a unilateral neck mass during the first weeks of life. Although self-limiting, early recognition is essential to prevent unnecessary investigations and to reduce the risk of complications such as congenital torticollis.
Case presentation
We report the case of a 3-week-old female neonate who presented with a painless, left-sided neck swelling of one week’s duration. Clinical examination revealed a firm, non-tender mass along the sternocleidomastoid muscle. Ultrasonography confirmed the diagnosis of Fibromatosis colli. The patient was managed conservatively with physiotherapy, resulting in near-complete resolution of the mass and restoration of normal neck mobility within three months.
Conclusion
Fibromatosis colli is an uncommon but clinically significant cause of neck swelling in neonates and may closely mimic neoplastic lesions. It should be considered in the differential diagnosis of unilateral neck masses in early infancy. Accurate diagnosis is typically achieved through targeted clinical examination complemented by ultrasonography. Early initiation of physiotherapy is highly effective, typically resulting in complete recovery without the need for surgical intervention. Timely recognition and differentiation from other neonatal neck masses are crucial to avoid unnecessary invasive procedures, alleviate parental anxiety, and prevent complications such as persistent torticollis and craniofacial asymmetry.
{"title":"Fibromatosis colli: A rare neck mass of the sternocleidomastoid muscle in an infant: A case report","authors":"Tesfa G/Meskel , Mesfin Wubishet , Nuri Mama , Ayalneh Demissie","doi":"10.1016/j.xocr.2025.100714","DOIUrl":"10.1016/j.xocr.2025.100714","url":null,"abstract":"<div><h3>Background</h3><div>Fibromatosis colli (FC), also known as sternocleidomastoid pseudotumor of infancy, is a rare benign proliferation of fibrous tissue within the sternocleidomastoid muscle. It typically presents as a unilateral neck mass during the first weeks of life. Although self-limiting, early recognition is essential to prevent unnecessary investigations and to reduce the risk of complications such as congenital torticollis.</div></div><div><h3>Case presentation</h3><div>We report the case of a 3-week-old female neonate who presented with a painless, left-sided neck swelling of one week’s duration. Clinical examination revealed a firm, non-tender mass along the sternocleidomastoid muscle. Ultrasonography confirmed the diagnosis of Fibromatosis colli. The patient was managed conservatively with physiotherapy, resulting in near-complete resolution of the mass and restoration of normal neck mobility within three months.</div></div><div><h3>Conclusion</h3><div>Fibromatosis colli is an uncommon but clinically significant cause of neck swelling in neonates and may closely mimic neoplastic lesions. It should be considered in the differential diagnosis of unilateral neck masses in early infancy. Accurate diagnosis is typically achieved through targeted clinical examination complemented by ultrasonography. Early initiation of physiotherapy is highly effective, typically resulting in complete recovery without the need for surgical intervention. Timely recognition and differentiation from other neonatal neck masses are crucial to avoid unnecessary invasive procedures, alleviate parental anxiety, and prevent complications such as persistent torticollis and craniofacial asymmetry.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100714"},"PeriodicalIF":0.3,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145570586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fungal sinusitis is a common otolaryngological disease; however, most cases involve the maxillary sinus, and cases of isolated fungus balls (FBs) in the frontal sinus are extremely rare. Herein, we describe the management of an isolated frontal sinus FB in a patient without underlying immunodeficiency. A 58-year-old man presented with a 1-month history of pain in his left forehead. Sinus computed tomography (CT) showed soft-tissue shadows with calcification in the left frontal sinus, and magnetic resonance imaging showed low signal intensity on T2-weighted images at the site of calcification on CT, suggesting the presence of an FB. The patient had a relatively severe and unique anatomical condition that appeared challenging to manage. The endoscopic modified Lothrop procedure (EMLP) was selected, and surgery was performed 3 months after the initial visit. An inside-out approach was used to reach the frontal sinus and unify the bilateral frontal sinuses into a single cavity. A powered irrigation system was used to irrigate and completely remove the entire fungal mass. The pathological findings showed clusters of Aspergillus. In summary, the EMLP was successfully performed, and the FB was completely removed without any complications in this case. The patient remains recurrence-free to date, and the wound site is easily observable via a fiberscope.
{"title":"A rare case of isolated frontal sinus fungus ball","authors":"Shin Ito , Satoko Kubo , Ryuzaburo Higo , Akane Hashizume , Fumihiko Matsumoto","doi":"10.1016/j.xocr.2025.100715","DOIUrl":"10.1016/j.xocr.2025.100715","url":null,"abstract":"<div><div>Fungal sinusitis is a common otolaryngological disease; however, most cases involve the maxillary sinus, and cases of isolated fungus balls (FBs) in the frontal sinus are extremely rare. Herein, we describe the management of an isolated frontal sinus FB in a patient without underlying immunodeficiency. A 58-year-old man presented with a 1-month history of pain in his left forehead. Sinus computed tomography (CT) showed soft-tissue shadows with calcification in the left frontal sinus, and magnetic resonance imaging showed low signal intensity on T2-weighted images at the site of calcification on CT, suggesting the presence of an FB. The patient had a relatively severe and unique anatomical condition that appeared challenging to manage. The endoscopic modified Lothrop procedure (EMLP) was selected, and surgery was performed 3 months after the initial visit. An inside-out approach was used to reach the frontal sinus and unify the bilateral frontal sinuses into a single cavity. A powered irrigation system was used to irrigate and completely remove the entire fungal mass. The pathological findings showed clusters of Aspergillus. In summary, the EMLP was successfully performed, and the FB was completely removed without any complications in this case. The patient remains recurrence-free to date, and the wound site is easily observable via a fiberscope.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100715"},"PeriodicalIF":0.3,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cleft lip and palate(CL/P) are among the most common orofacial birth defects, often associated with feeding, hearing,communication, and speech problems. A multidisciplinary approach is required for optimal management.
This report describes a 4-year-old girl with an unrepaired cleft palate who presented with multiple articulation errors, reduced speech intelligibility, and low intraoral pressure. Following surgical repair of the palate, she received intensive online speech therapy. Speech assessment demonstrated a significant improvement. Compensatory articulation errors decreased progressively and reached zero at follow-up. Based on perceptual assessment, hypernasality was significantly reduced after the cleft palate surgery.
{"title":"A 4-year-old girl with an unrepaired cleft palate: Outcomes of late intervention","authors":"Mahdiye Tavakoli , Fariba Jahangiri , Gholamreza Bayazian , Nahid Jalilevand , Reyhane Mohamadi","doi":"10.1016/j.xocr.2025.100713","DOIUrl":"10.1016/j.xocr.2025.100713","url":null,"abstract":"<div><div>Cleft lip and palate(CL/P) are among the most common orofacial birth defects, often associated with feeding, hearing,communication, and speech problems. A multidisciplinary approach is required for optimal management.</div><div>This report describes a 4-year-old girl with an unrepaired cleft palate who presented with multiple articulation errors, reduced speech intelligibility, and low intraoral pressure. Following surgical repair of the palate, she received intensive online speech therapy. Speech assessment demonstrated a significant improvement. Compensatory articulation errors decreased progressively and reached zero at follow-up. Based on perceptual assessment, hypernasality was significantly reduced after the cleft palate surgery.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100713"},"PeriodicalIF":0.3,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145570585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sinonasal mucosal melanoma (SNMM) is an aggressive subtype of melanoma that represents <5 % of head and neck melanomas and constitutes less than 1 % of systemic melanoma cases.
Case presentation
A 54-year-old female presented with a 5-month history of unilateral recurrent epistaxis, anosmia, and nasal obstruction. Nasal endoscopy showed a bleeding fleshy lesion occupying the right nasal cavity, extending to the nasal floor and nasal septum. Pathological examination and immunohistochemistry (IHC) findings confirmed the diagnosis of SNMM.
Conclusion
SNMM in the head and neck region can manifest with nonspecific symptoms. The diagnosis often requires a combination of clinical, pathological, and IHC studies.
{"title":"A rare case report of sinonasal mucosal melanoma in the maxillary sinus","authors":"Molham Alahmad , Venus Hussain Ameen , Mohammad Jomaa , Abdulmajeed Yousfan","doi":"10.1016/j.xocr.2025.100712","DOIUrl":"10.1016/j.xocr.2025.100712","url":null,"abstract":"<div><h3>Introduction</h3><div>Sinonasal mucosal melanoma (SNMM) is an aggressive subtype of melanoma that represents <5 % of head and neck melanomas and constitutes less than 1 % of systemic melanoma cases.</div></div><div><h3>Case presentation</h3><div>A 54-year-old female presented with a 5-month history of unilateral recurrent epistaxis, anosmia, and nasal obstruction. Nasal endoscopy showed a bleeding fleshy lesion occupying the right nasal cavity, extending to the nasal floor and nasal septum. Pathological examination and immunohistochemistry (IHC) findings confirmed the diagnosis of SNMM.</div></div><div><h3>Conclusion</h3><div>SNMM in the head and neck region can manifest with nonspecific symptoms. The diagnosis often requires a combination of clinical, pathological, and IHC studies.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"38 ","pages":"Article 100712"},"PeriodicalIF":0.3,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.xocr.2025.100710
Miles J. Klimara , Eirene Alexandrou , Anand Kanagasabapathy , Matthew R. Hoffman
Background
Tumoral calcinosis (TC) is a rare, benign calcium hydroxyapatite deposition typically affecting periarticular tissue of large joints, which may occur sporadically or in association with hyperphosphatemia. Laryngeal TC has been reported in several patients, uniformly in the fifth and sixth decade of life. Presented is a case of sporadic combined intra-laryngeal and extra-laryngeal TC in a child.
Case discussion
A 10-year-old female presented with a right neck mass and stridor with activity. Flexible laryngoscopy revealed fullness of the right false vocal fold without intraluminal mass, and computed tomography showed a large, calcified, intra- and extra-laryngeal mass passing through the thyrohyoid space. Open resection was performed. Surgical pathology revealed TC. Laboratory and endocrine evaluation did not reveal any underlying metabolic etiology, supporting a diagnosis of primary laryngeal TC. Airway management, approach to resection, and published cases of laryngeal TC are reviewed.
Conclusion
TC of the larynx is an exceedingly rare entity. Given benign nature of this disease process, a conservative approach is favored when resection is pursued, with preservation of normal structures in order to minimize morbidity. Upon diagnosis, multidisciplinary evaluation should be pursued to rule out underlying endocrine, metabolic, and genetic disorders.
{"title":"An unusual laryngeal mass: primary tumoral calcinosis of the larynx in a child","authors":"Miles J. Klimara , Eirene Alexandrou , Anand Kanagasabapathy , Matthew R. Hoffman","doi":"10.1016/j.xocr.2025.100710","DOIUrl":"10.1016/j.xocr.2025.100710","url":null,"abstract":"<div><h3>Background</h3><div>Tumoral calcinosis (TC) is a rare, benign calcium hydroxyapatite deposition typically affecting periarticular tissue of large joints, which may occur sporadically or in association with hyperphosphatemia. Laryngeal TC has been reported in several patients, uniformly in the fifth and sixth decade of life. Presented is a case of sporadic combined intra-laryngeal and extra-laryngeal TC in a child.</div></div><div><h3>Case discussion</h3><div>A 10-year-old female presented with a right neck mass and stridor with activity. Flexible laryngoscopy revealed fullness of the right false vocal fold without intraluminal mass, and computed tomography showed a large, calcified, intra- and extra-laryngeal mass passing through the thyrohyoid space. Open resection was performed. Surgical pathology revealed TC. Laboratory and endocrine evaluation did not reveal any underlying metabolic etiology, supporting a diagnosis of primary laryngeal TC. Airway management, approach to resection, and published cases of laryngeal TC are reviewed.</div></div><div><h3>Conclusion</h3><div>TC of the larynx is an exceedingly rare entity. Given benign nature of this disease process, a conservative approach is favored when resection is pursued, with preservation of normal structures in order to minimize morbidity. Upon diagnosis, multidisciplinary evaluation should be pursued to rule out underlying endocrine, metabolic, and genetic disorders.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"37 ","pages":"Article 100710"},"PeriodicalIF":0.3,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}