{"title":"Intestinal volvulus without malrotationの診断時期と治療成績の検討","authors":"井上 成一朗, 小高 明雄, 牟田 裕紀, 竹内 優太, 加部 一彦, 馬場 一憲","doi":"10.11164/JJSPS.56.4_376","DOIUrl":"https://doi.org/10.11164/JJSPS.56.4_376","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125147437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ewing’s sarcoma family of tumors（ESFT）肝転移に対して2度の完全腹腔鏡下肝部分切除術を施行した1例","authors":"卓 五味, 健治 福永, 光宏 米田, 杏子 中村, 聡 西本, 雪乃 塚崎, 弘人 山田, 雅史 神山, 千賀 仁谷, 景繁 金沢","doi":"10.11164/JJSPS.55.7_1170","DOIUrl":"https://doi.org/10.11164/JJSPS.55.7_1170","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130462062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-20DOI: 10.11164/JJSPS.53.6_1200
慶徳 李
{"title":"症例報告 右鼠径ヘルニアが疑われ紹介され腸骨下腹神経切離によりすみやかに治癒しえたACNES(Anterior Cutaneous Nerve Entrapment Syndrome)の8歳男児の1例","authors":"慶徳 李","doi":"10.11164/JJSPS.53.6_1200","DOIUrl":"https://doi.org/10.11164/JJSPS.53.6_1200","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127139191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anterior cutaneous nerve entrapment syndrome（ACNES）の2小児例","authors":"武 浅井, 喜信 岩村, 章 新居, 芳江 浅井","doi":"10.11164/JJSPS.53.4_944","DOIUrl":"https://doi.org/10.11164/JJSPS.53.4_944","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122021799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"小児膵solid-pseudopapillary neoplasmに対して腹腔鏡下脾温存膵体尾部切除術を施行した1例","authors":"雄毅 竹内, 泰三 古川, 正和 竹本, 誠久 文野, 達郎 田尻","doi":"10.11164/JJSPS.53.4_938","DOIUrl":"https://doi.org/10.11164/JJSPS.53.4_938","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122690419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-20DOI: 10.11164/JJSPS.52.7_1315
二郎 津川, 冨岡 雄一郎, 栄治 西島
{"title":"初回手術としてpartial cricotracheal resection（PCTR）を行った後天性声門下腔狭窄症の1例","authors":"二郎 津川, 冨岡 雄一郎, 栄治 西島","doi":"10.11164/JJSPS.52.7_1315","DOIUrl":"https://doi.org/10.11164/JJSPS.52.7_1315","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115077902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-20DOI: 10.11164/JJSPS.52.6_1251
智 牧田, 広夫 内田
{"title":"術前／術後化学療法としてGemcitabine/Oxaliplatin療法（GEMOX療法）を施行したfibrolamellar hepatocellular carcinomaの1例","authors":"智 牧田, 広夫 内田","doi":"10.11164/JJSPS.52.6_1251","DOIUrl":"https://doi.org/10.11164/JJSPS.52.6_1251","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123540544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"腹腔鏡下噴門形成術におけるanterior wrappingとposterior wrapping治療成績の検討","authors":"宏平 坂井, 泰三 古川, 修 木村, 真弓 東, 誠久 文野, 重善 青井, 達郎 田尻","doi":"10.11164/JJSPS.52.1_78","DOIUrl":"https://doi.org/10.11164/JJSPS.52.1_78","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125506130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-10-20DOI: 10.11164/JJSPS.51.6_1048
Toshiaki Takahashi, F. Friedmacher, P. Puri
Purpose: Pulmonary hypoplasia (PH) remains a major therapeutic challenge associated with congenital diaphragmatic hernia (CDH). Leukemia inhibitory factor (LIF) and its receptor (LIFR) play an essential role in airway branching morphogenesis in developing fetal lungs. With a significant increase just before birth, high LIF expression level has been demonstrated in the pulmonary epithelium, whereas LIFR is mainly expressed in the surrounding mesenchyme. Furthermore, LIFdeficient fetuses exhibit PH with defective airway tissue. We hypothesized that pulmonary LIF and LIFR expression levels are decreased during lung branching morphogenesis in nitrofen-induced PH. Methods: Timed-pregnant rats received either nitrofen or a vehicle on gestational day 9 (D9). Fetuses were harvested on D15, D18 and D21, and dissected lungs were divided into control and nitrofen-exposed groups (n = 12 per time point and group). The pulmonary expression levels of LIF and LIFR were analyzed by quantitative real-time polymerase chain reaction. Immunohistochemical staining of LIF and LIFR was performed to evaluate protein expression and localization in branching airway tissue. Results: Relative mRNA expression levels of LIF and LIFR were significantly reduced in the lungs of nitrofen-exposed fetuses on D15 (0.21 ± 0.13 vs 0.49 ± 0.19; p < 0.05 and 0.24 ± 0.13 vs. 0.36 ± 0.12; p < 0.05), D18 (0.11 ± 0.07 vs. 0.49 ± 0.41; p < 0.05 and 0.10 ± 0.03 vs. 0.16 ± 0.03; p < 0.05) and D21 (0.13 ± 0.04 vs. 0.27 ± 0.05; p < 0.05 and 0.18 ± 0.03 vs. 0.34 ± 0.12; p < 0.05) compared with controls. LIF immunoreactivity was markedly diminished in the distal airway epithelium, whereas LIFR expression level was decreased in mesenchymal cells surrounding terminal bronchioles and alveoli on D15, D18 and D21 compared with controls. Conclusion: Decreased pulmonary LIF and LIFR expression levels may disrupt epithelialmesenchymal interactions during lung branching morphogenesis and cause PH in the nitrofen-induced CDH model.
{"title":"Decreased Expression Levels of Leukemia Inhibitory Factor and Its Receptor During Airway Branching Morphogenesis in Nitrofen-Induced Hypoplastic Lungs","authors":"Toshiaki Takahashi, F. Friedmacher, P. Puri","doi":"10.11164/JJSPS.51.6_1048","DOIUrl":"https://doi.org/10.11164/JJSPS.51.6_1048","url":null,"abstract":"Purpose: Pulmonary hypoplasia (PH) remains a major therapeutic challenge associated with congenital diaphragmatic hernia (CDH). Leukemia inhibitory factor (LIF) and its receptor (LIFR) play an essential role in airway branching morphogenesis in developing fetal lungs. With a significant increase just before birth, high LIF expression level has been demonstrated in the pulmonary epithelium, whereas LIFR is mainly expressed in the surrounding mesenchyme. Furthermore, LIFdeficient fetuses exhibit PH with defective airway tissue. We hypothesized that pulmonary LIF and LIFR expression levels are decreased during lung branching morphogenesis in nitrofen-induced PH. Methods: Timed-pregnant rats received either nitrofen or a vehicle on gestational day 9 (D9). Fetuses were harvested on D15, D18 and D21, and dissected lungs were divided into control and nitrofen-exposed groups (n = 12 per time point and group). The pulmonary expression levels of LIF and LIFR were analyzed by quantitative real-time polymerase chain reaction. Immunohistochemical staining of LIF and LIFR was performed to evaluate protein expression and localization in branching airway tissue. Results: Relative mRNA expression levels of LIF and LIFR were significantly reduced in the lungs of nitrofen-exposed fetuses on D15 (0.21 ± 0.13 vs 0.49 ± 0.19; p < 0.05 and 0.24 ± 0.13 vs. 0.36 ± 0.12; p < 0.05), D18 (0.11 ± 0.07 vs. 0.49 ± 0.41; p < 0.05 and 0.10 ± 0.03 vs. 0.16 ± 0.03; p < 0.05) and D21 (0.13 ± 0.04 vs. 0.27 ± 0.05; p < 0.05 and 0.18 ± 0.03 vs. 0.34 ± 0.12; p < 0.05) compared with controls. LIF immunoreactivity was markedly diminished in the distal airway epithelium, whereas LIFR expression level was decreased in mesenchymal cells surrounding terminal bronchioles and alveoli on D15, D18 and D21 compared with controls. Conclusion: Decreased pulmonary LIF and LIFR expression levels may disrupt epithelialmesenchymal interactions during lung branching morphogenesis and cause PH in the nitrofen-induced CDH model.","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125023223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-12-20DOI: 10.11164/JJSPS.48.7_1073_2
慧 大山, 宗親 脇坂, 秀樹 島, 秀樹 長江, 昭司 渡辺, 宏隆 小泉, 博昭 北川
{"title":"2. 呼吸困難を呈した副咽頭間隙腫瘍の1例(一般演題,第47回日本小児外科学会関東甲信越地方会)","authors":"慧 大山, 宗親 脇坂, 秀樹 島, 秀樹 長江, 昭司 渡辺, 宏隆 小泉, 博昭 北川","doi":"10.11164/JJSPS.48.7_1073_2","DOIUrl":"https://doi.org/10.11164/JJSPS.48.7_1073_2","url":null,"abstract":"","PeriodicalId":372114,"journal":{"name":"Journal of the Japanese Society of Pediatric Surgeons","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115923247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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