{"title":"4% 5-Fluoruracil in cream for the treatment of actinic keratosis of the vertex","authors":"Andrea Kohutová","doi":"10.36290/der.2023.037","DOIUrl":"https://doi.org/10.36290/der.2023.037","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"54 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139252891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atopic dermatitis (AD) is a chronic pruritic and eczematous skin condition that is characterized by repeated exacerbations and remissions. In recent years, its pathogenesis has been more clearly elucidated, and treatments targeting molecules that are important for its progression have been developed. In 2018, dupilumab, which blocks the common receptor of interleukin (IL)-4 and IL-13, was introduced as a new treatment for AD, representing a significant turning point in the treatment of AD. Since the pathogenesis of AD is complicated, other biological and molecularly targeted agents are also expected to be introduced in the future. In this article, we report our experience in treating atopic dermatitis patients with dupilumab at our hospital, describe the efficacy and safety of drugs used for AD and provide a review of the recent literature on new drugs that are expected to be approved in the future.
特应性皮炎（AD）是一种慢性瘙痒性和湿疹性皮肤病，其特点是反复加重和缓解。近年来，特应性皮炎的发病机制得到了更清晰的阐释，针对特应性皮炎进展的重要分子的治疗方法也相继问世。2018年，阻断白细胞介素（IL）-4和IL-13共同受体的dupilumab作为AD的新疗法问世，成为AD治疗的重要转折点。由于AD的发病机制复杂，预计未来还会有其他生物和分子靶向药物问世。在本文中，我们将报告本院使用杜必鲁单抗治疗特应性皮炎患者的经验，介绍用于治疗 AD 的药物的疗效和安全性，并对近期有望在未来获得批准的新药进行文献综述。
{"title":"New treatments for atopic dermatitis","authors":"Filip Rob","doi":"10.36290/der.2023.035","DOIUrl":"https://doi.org/10.36290/der.2023.035","url":null,"abstract":"Atopic dermatitis (AD) is a chronic pruritic and eczematous skin condition that is characterized by repeated exacerbations and remissions. In recent years, its pathogenesis has been more clearly elucidated, and treatments targeting molecules that are important for its progression have been developed. In 2018, dupilumab, which blocks the common receptor of interleukin (IL)-4 and IL-13, was introduced as a new treatment for AD, representing a significant turning point in the treatment of AD. Since the pathogenesis of AD is complicated, other biological and molecularly targeted agents are also expected to be introduced in the future. In this article, we report our experience in treating atopic dermatitis patients with dupilumab at our hospital, describe the efficacy and safety of drugs used for AD and provide a review of the recent literature on new drugs that are expected to be approved in the future.","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139254266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial skin infections I. - infections caused by gram-positive bacteria","authors":"Ondřej Kodet","doi":"10.36290/der.2023.034","DOIUrl":"https://doi.org/10.36290/der.2023.034","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"45 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139254474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bimekizumab in the treatment of psoriasis and psoriatic arthritis","authors":"J. Šternberský, Martin Tichý","doi":"10.36290/der.2023.039","DOIUrl":"https://doi.org/10.36290/der.2023.039","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"62 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139253892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical improvement in a patient with lichen planopilaris","authors":"Nadezhda Vidolova Brabcová","doi":"10.36290/der.2023.016","DOIUrl":"https://doi.org/10.36290/der.2023.016","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115439709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current view on the treatment of nail psoriasis","authors":"G. Janoušková","doi":"10.36290/der.2023.013","DOIUrl":"https://doi.org/10.36290/der.2023.013","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116616382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of microbiome and probiotics in photoprotection and skin aging","authors":"Tereza Chrpová Maulenová","doi":"10.36290/der.2023.012","DOIUrl":"https://doi.org/10.36290/der.2023.012","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116159289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psoriasis and inflammatory bowel disease","authors":"Kristína Gibalová","doi":"10.36290/der.2023.014","DOIUrl":"https://doi.org/10.36290/der.2023.014","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127010560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ulcus cruris venosum in the context of patients' quality of life","authors":"I. Ondriová, T. Fertaľová, L. Hadašová","doi":"10.36290/der.2023.015","DOIUrl":"https://doi.org/10.36290/der.2023.015","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117197769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe form of atopic dermatitis - Successful treatment with abrocitinib","authors":"Michaela Chmelíková, Milena Tanczosova","doi":"10.36290/der.2023.017","DOIUrl":"https://doi.org/10.36290/der.2023.017","url":null,"abstract":"","PeriodicalId":375534,"journal":{"name":"Dermatologie pro praxi","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114252374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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