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Olfactory Dysfunction in Parkinson's Disease, Its Functional and Neuroanatomical Correlates. 帕金森病的嗅觉功能障碍及其功能和神经解剖学相关性
IF 1.6 Q3 Economics, Econometrics and Finance Pub Date : 2023-06-05 eCollection Date: 2023-06-01 DOI: 10.3390/neurosci4020013
Gabriel Torres-Pasillas, Donají Chi-Castañeda, Porfirio Carrillo-Castilla, Gerardo Marín, María Elena Hernández-Aguilar, Gonzalo Emiliano Aranda-Abreu, Jorge Manzo, Luis I García

Parkinson's disease (PD) is known for its motor alterations, but the importance of non-motor symptoms (NMSs), such as olfactory dysfunction (OD), is increasingly recognized. OD may manifest during the prodromal period of the disease, even before motor symptoms appear. Therefore, it is suggested that this symptom could be considered a marker of PD. This article briefly describes PD, the evolution of the knowledge about OD in PD, the prevalence of this NMS and its role in diagnosis and as a marker of PD progression, the assessment of olfaction in patients with PD, the role of α-synuclein and its aggregates in the pathophysiology of PD, and then describes some functional, morphological, and histological alterations observed in different structures related to the olfactory system, such as the olfactory epithelium, olfactory bulb, anterior olfactory nucleus, olfactory tract, piriform cortex, hippocampus, orbitofrontal cortex, and amygdala. In addition, considering the growing evidence that suggests that the cerebellum is also involved in the olfactory system, it has also been included in this work. Comprehending the existing functional and neuroanatomical alterations in PD could be relevant for a better understanding of the mechanisms behind OD in patients with this neurodegenerative disorder.

帕金森病(PD)以其运动改变而闻名,但嗅觉功能障碍(OD)等非运动症状(NMS)的重要性也日益得到认可。嗅觉障碍可能在疾病的前驱期表现出来,甚至在运动症状出现之前。因此,有人认为这一症状可被视为帕金森病的标志。本文简要介绍了帕金森氏症、帕金森氏症患者嗅觉缺失的知识演变、这一 NMS 的发病率及其在诊断中的作用和作为帕金森氏症进展标志的作用、对帕金森氏症患者嗅觉的评估、α-突触核蛋白及其聚集体在帕金森氏症病理生理学中的作用、然后描述了在嗅觉系统相关的不同结构中观察到的一些功能、形态和组织学改变,如嗅上皮、嗅球、前嗅核、嗅束、梨状皮层、海马、眶额皮层和杏仁核。此外,考虑到越来越多的证据表明小脑也参与了嗅觉系统,本研究也将其包括在内。了解帕金森病现有的功能和神经解剖学改变有助于更好地理解这种神经退行性疾病患者嗅觉缺失背后的机制。
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引用次数: 0
The Negative Effect of COVID 19 Pandemic on Sports Leisure Recreation Retailers, and its Solutions 新冠肺炎疫情对体育休闲娱乐零售商的负面影响及对策
Q3 Economics, Econometrics and Finance Pub Date : 2022-01-01 DOI: 10.15722/jds.20.02.202202.91
D. Seong, N. Seong
Purpose: The sports industry is a major form of leisure and entertainment, but the industry was tremendously affected by the Covid-19 pandemic. This study gives solutions for sports leisure retail stores to the effects of the Covid-19 crisis on consumers' sports products purchasing habits and then gives a logical conclusion regarding the findings of the topic. Research design, data and methodology: Scant research is available to feedback for owners and managers of sports leisure retail stores which elements could be considered to recover their business prior to the pandemic. For achieving this, this study investigated total 284 responses in the retail stores and conducted the ANOVA analysis to compare the level of intensity on the impact Covid 19 pandemic. Results: Our findings suggests that there was a statistically recognizable difference at the significance level of probability between the mean value of the impact index of Covid 19 pandemic and key recovery strategies, indicating the high degree of Covid 19 impact can be reducing by four solutions. Conclusions: Finally, this study concludes the specific entertainment elements that influence the purchasing behavior of consumers will ensure that the Sports industry deals with its internal problems first without necessarily looking at the outside factors such as the pandemic © The Author(s)
目的:体育产业是休闲娱乐的主要形式,但该行业受到Covid-19大流行的巨大影响。本研究为体育休闲零售商店提供解决方案,以应对Covid-19危机对消费者体育产品购买习惯的影响,然后对该主题的研究结果给出逻辑结论。研究设计、数据和方法:可供体育休闲零售商店所有者和管理人员反馈的研究很少,可以考虑哪些因素可以在大流行之前恢复其业务。为了实现这一目标,本研究调查了零售商店的284份回复,并进行了方差分析,以比较Covid - 19大流行影响的强度水平。结果:我们的研究结果表明,Covid - 19大流行影响指数均值与关键恢复策略在概率显著性水平上存在统计学上可识别的差异,表明4种解决方案可以降低Covid - 19影响的高度。结论:最后,本研究得出影响消费者购买行为的特定娱乐因素将确保体育产业首先处理其内部问题,而不必考虑流行病等外部因素©作者(s)
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引用次数: 1
Impulse Buying: The Influence of Impulse Buying Tendency, Urge to Buy and Gender on Impulse Buying of the Retail Customers 冲动购买:冲动购买倾向、购买冲动和性别对零售顾客冲动购买的影响
Q3 Economics, Econometrics and Finance Pub Date : 2021-07-01 DOI: 10.15722/JDS.19.7.202107.101
A. Utama, Hunik Sri Runing Sawitri, B. Haryanto, Lilik Wahyudi
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引用次数: 4
Website Quality, E-satisfaction, and E-loyalty of Users Based on The Virtual Distribution Channel 基于虚拟分销渠道的网站质量、e -满意度与用户e -忠诚度
Q3 Economics, Econometrics and Finance Pub Date : 2021-07-01 DOI: 10.15722/JDS.19.7.202107.113
D. R. Pandjaitan, Mahrinasari, Bram Hadianto
Purpose: Technology induces the virtual distribution channel to exist, especially for booking a room online. This situation, indeed, provides an alternative for the customers to book based on their budget through digital platforms. One platform offering competitive prices is virtual hotel operators, such as Airbnb, OYO, RedDoorz, and Airy Rooms. Preferably, after using their platform, the user should be satisfied and loyal. Hence, this investigation aims to prove some associations. The first is between e-satisfaction and e-loyalty. The second is between website quality and e-satisfaction. The final is between website quality and e-loyalty. Research design, data, and methodology: This study is quantitatively designed with the sample of 350 users of the virtual hotel operator applications in Bandar Lampung: Airbnb, OYO, RedDoorz, and Airy, as the samples. Therefore, by denoting this sample size, the structural equation model based on covariance is utilized to examine the three hypotheses proposed. Also, to get the responses, this study uses a survey through a questionnaire. Result: This investigation demonstrates the positive relationship between e-satisfaction and e-loyalty. Additionally, website quality positively associates with e-satisfaction and e-loyalty. Conclusion: The virtual hotel operators must have the superiority on their website-based application to update the information based on the room availability and price, ensure online transaction safety, and facilitate its utilization to maintain long-term satisfaction and loyalty virtually. Keywords: E-loyalty, E-satisfaction, Virtual Distribution Channel, Website Superiority
目的:技术诱导虚拟分销渠道的存在,特别是对于在线预订房间。事实上,这种情况为客户提供了一种通过数字平台根据预算预订的选择。一个提供有竞争力价格的平台是虚拟酒店运营商,如Airbnb、OYO、RedDoorz和Airy Rooms。优选地,在使用他们的平台之后,用户应该感到满意和忠诚。因此,本次调查旨在证明一些关联。第一个是介于电子满足感和电子忠诚之间。二是网站质量和电子满意度之间的关系。最终是在网站质量和电子忠诚度之间。研究设计、数据和方法:本研究以班达蓝蓬的350名虚拟酒店运营商应用程序用户为样本进行定量设计:Airbnb、OYO、RedDoorz和Airy。因此,通过表示该样本量,利用基于协方差的结构方程模型来检验所提出的三个假设。此外,为了得到答案,本研究通过问卷调查进行了调查。结果:本研究证实了电子满意度与电子忠诚度之间的正相关关系。此外,网站质量与电子满意度和电子忠诚度呈正相关。结论:虚拟酒店运营商必须在其基于网站的应用程序上具有优势,以根据客房供应情况和价格更新信息,确保在线交易安全,并促进其使用,从而在虚拟环境中保持长期的满意度和忠诚度。关键词:电子忠诚度、电子满意度、虚拟分销渠道、网站优势
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引用次数: 4
Distribution of supply chain capabilities and firm’s sustainable development 供应链能力分布与企业可持续发展
Q3 Economics, Econometrics and Finance Pub Date : 2021-05-01 DOI: 10.15722/JDS.19.5.202105.5
T. To, T. Than, D. T. Nguyen, Dat Ngoc Nguyen
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引用次数: 3
The Impact of Korean Wave on the Distribution of Consumer Goods Exports 韩流对消费品出口流通的影响
Q3 Economics, Econometrics and Finance Pub Date : 2021-04-30 DOI: 10.15722/JDS.19.4.202104.37
Hun Kim, Hye-Sun Kim, Byeng-Hee Chang, Jiseob Park
Purpose: The purpose of this study is to provide a basis for establishing a policy to promote the export of Korean goods through the economic ripple effect of the Korean Wave. From 2001 to 2017, cultural goods exports and consumer goods exports data to 102 countries were used to estimate the effect of cultural goods exports on domestic consumer goods exports. Research design, data and methodology: Based on the Gravity Model, we analyzed the effects of domestic film, publishing, music, broadcasting, clothing, cosmetics, processed food, IT products, and automobiles on the export of consumer goods. Results: The empirical analysis estimated the trade creation effect of exports of cultural products driving exports of consumer goods and found that a 1% increase in exports of cultural products increased 0.136% in exports of consumer goods. Conclusions: The average rate of change in consumer goods exports due to changes in cultural product exports was 22.44, which could be interpreted as an increase of $2,244 in exports of consumer goods such as IT products, cosmetics, clothing, and processed foods. According to the analysis of export-driven effects of each consumer item by dividing cultural products by sector, the effects of export of processed foods, clothing, cosmetics, IT products, and film, music, publishing exports were statistically significant.
目的:本研究旨在为制定通过韩流经济连锁反应促进韩国商品出口的政策提供依据。2001年至2017年,文化产品出口和102个国家的消费品出口数据用于估计文化产品出口对国内消费品出口的影响。研究设计、数据和方法:基于引力模型,我们分析了国内电影、出版、音乐、广播、服装、化妆品、加工食品、IT产品和汽车对消费品出口的影响。结果:实证分析估计了文化产品出口对消费品出口的贸易创造效应,发现文化产品出口增长1%,消费品出口增长0.136%。结论:由于文化产品出口的变化,消费品出口的平均变化率为22.44,这可以解释为信息技术产品、化妆品、服装和加工食品等消费品出口增加了2244美元。根据按部门划分文化产品对每个消费品的出口驱动效应的分析,加工食品、服装、化妆品、IT产品以及电影、音乐、出版出口的出口效应具有统计学意义。
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引用次数: 6
Effect of Improving Quality by Changing the Distribution Method of Shrimp Culture 改变对虾养殖分配方式提高品质的效果
Q3 Economics, Econometrics and Finance Pub Date : 2021-04-30 DOI: 10.15722/JDS.19.4.202104.53
Woo-Taeg Kwon, Min-Jae Jung, Hyun-Jin Woo, Woo-Sik Lee, Lee-Seung Kwon
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引用次数: 1
Topics and Sentiment Analysis Based on Reviews of Omni-Channel Retailing 基于全渠道零售评论的话题与情感分析
Q3 Economics, Econometrics and Finance Pub Date : 2021-04-30 DOI: 10.15722/JDS.19.4.202104.25
soon-hong Kim, B. Yoo
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引用次数: 3
The Role of Technological Progress in the Distribution sector: Evidence from Saudi Arabia Wholesale and Retail Trade Sector 技术进步在分销部门的作用:来自沙特阿拉伯批发和零售贸易部门的证据
Q3 Economics, Econometrics and Finance Pub Date : 2021-03-01 DOI: 10.15722/JDS.19.3.202103.15
J. Alzyadat, Monira Saleh Almuslamani
Purpose: This study aims to identify the role of technological progress in the distribution sector in Saudi Arabia. Research design, data, and...
目的:本研究旨在确定技术进步在沙特阿拉伯分销部门的作用。研究设计、数据和…
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引用次数: 3
Relational Benefits, Alternative Attractiveness and Customer Loyalty: Implication for Service Distribution Channels 关系利益、替代吸引力与顾客忠诚度:对服务分销渠道的启示
Q3 Economics, Econometrics and Finance Pub Date : 2021-01-01 DOI: 10.15722/JDS.19.1.202101.5
Kwangkun Lee, Chen-Qi Ou, Choong-Ik Choi
Purpose: This study explores the types of relational benefits that generate loyalty to room-sharing services among Chinese customers based on the relationship marketing literature. The study also examines the moderating effect of alternative attractiveness on this relationship. Research design, data and methodology: Based on research hypotheses, questionnaires with items measuring the proposed constructs in three dimensions, including relational benefits, alternative attractiveness, and customer loyalty, were designed to test the hypotheses. Data were collected via an online questionnaire of 220 room-sharing service customers in China. Results: Results verify the effects of relational benefits on customers’ loyalty to room-sharing services and the mediating effect of alternative attractiveness. More specifically, confidence, social, and safety benefits positively affect customer loyalty to room-sharing services, and alternative attractiveness moderates only the effect of social benefits. Conclusions: The results suggest that room-sharing service providers should concentrate on providing confidence, social, and safety benefits to maintain long-term relationships with customers. This study also provides practical implication for building relationships between channel members in service distribution channels. The study concludes that without customer relationships marketing for managing collaborative and social communication channels, the entire distribution channel might lose out eventually.
目的:本研究在关系营销文献的基础上,探讨中国顾客对客房共享服务产生忠诚的关系利益类型。该研究还考察了另类吸引力对这种关系的调节作用。研究设计、数据和方法:基于研究假设,设计了问卷,从关系利益、替代吸引力和客户忠诚度三个维度测量所提出的结构,以检验假设。通过对中国220名客房共享服务客户的在线问卷调查收集数据。结果:研究结果验证了关系利益对客房共享服务客户忠诚度的影响以及替代吸引力的中介作用。更具体地说,信心、社会和安全利益正向影响客户对客房共享服务的忠诚度,而替代吸引力仅调节社会利益的影响。结论:研究结果表明,客房共享服务提供商应专注于提供信心、社会和安全效益,以维持与客户的长期关系。本研究也为服务分销渠道中渠道成员关系的建立提供了实践启示。该研究的结论是,如果没有客户关系营销来管理协作和社交沟通渠道,整个分销渠道最终可能会失败。
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引用次数: 3
期刊
Journal of Distribution Science
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