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2008 21st IEEE International Symposium on Computer-Based Medical Systems最新文献

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Interface for Accessing Pharmacological Information 访问药理学信息的接口
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.110
T. Karlsson
Pharmacological therapy is an increasingly complex medical activity. Databases with information on drug-drug interactions, side-effects etc. would complement traditional electronic patient journal systems and provide decision support for pharmacological therapy. To facilitate the use of such databases, drug terminology is essential to allow communication with existing information systems. Well- specified software interfaces would encourage and simplify usage of drug databases. This paper reports a software interface for accessing drug information.
药物治疗是一项日益复杂的医学活动。包含药物相互作用、副作用等信息的数据库将补充传统的电子患者期刊系统,并为药物治疗提供决策支持。为了方便使用这种数据库,药物术语是必不可少的,以便与现有的信息系统进行通信。良好的软件接口将鼓励和简化药物数据库的使用。本文报道了一种获取药品信息的软件接口。
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引用次数: 2
Network P2P for exploring and visualization of proteomic data produced by two dimensional electrophoresis 用于二维电泳产生的蛋白质组学数据的探索和可视化的网络P2P
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.74
G. Mercurio, S. Maglio, A. Agrusti, G. D. Nunzio, R. Cataldo, I. Mitri, M. Favetta, A. Massafra, G. Marsella, D. Vergara, M. Maffia
Our working group has started a project aiming at the development of analysis algorithms devoted to images produced by two-dimensional electrophoresis (2-DE) for general applications in the field of proteomics. General analysis problems have been addressed, with the ultimate goal of the maximization of the "automation level" of the analysis procedure, without reducing the accuracy now reachable only with manual intervention. For this purpose, the working group is analyzing 2-DE images that a real ready stored or that will be produced by means of the instrumentation and the know-how of the biologists participating to the project. It's obvious that the "key" for the project success is primarily the availability of many images produced by different groups, but especially their "comparability", and their significant "clinical contextualization". For these reasons, the group has started the implementation of federation of heterogeneous biobanks of images founded on open registry/repository for P2P architecture (ebXML RR), on images stored with standard metadata for their comparability (EFMI MIP) (A. Horsch et al., 2005), and on standard electronic documents for their clinical contextualization (HL7 CDA) (G. Mercurio and A. Rossi Mori). This paper summarizes the concepts of the initiative, describes its current state and presents an overview of related work.
我们的工作组已经启动了一个项目,旨在开发专门用于蛋白质组学领域中一般应用的二维电泳(2-DE)图像的分析算法。一般的分析问题已经解决,最终目标是分析过程的“自动化水平”最大化,而不降低现在只能通过人工干预达到的准确性。为此目的,工作组正在分析已实际储存或将通过仪器和参与该项目的生物学家的专门知识产生的2-DE图像。很明显,项目成功的“关键”主要是不同群体制作的许多图像的可用性,但尤其是它们的“可比性”,以及它们显著的“临床情境化”。由于这些原因,该小组已经开始实施基于P2P架构的开放注册/存储库(ebXML RR),基于标准元数据存储的图像(EFMI MIP) (A. Horsch等人,2005),以及基于标准电子文档的临床上下文化(HL7 CDA) (G. Mercurio和A. Rossi Mori)的异构图像生物库联合。本文总结了倡议的概念,描述了倡议的现状,并对相关工作进行了概述。
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引用次数: 1
MapFace - An Editor for MetaMap Transfer (MMTx) MapFace -用于元地图传输(MMTx)的编辑器
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.116
K. Kaiser, T. Gschwandtner, P. Martini
Mapping concepts from medical terminologies, such as the UMLS, to medical documents is a prerequisite for many tasks of (automatically) processing documents. Due to the nature of the UMLS and the tools to accomplish the mapping, it is not always possible to achieve a correct and unambiguous mapping. This drawback led us to the development of an editor for correcting the obtained information. Our editor, MapFace, visualizes information received by the MetaMap Transfer (MMTx) program and enables users to edit and correct this information on both a conceptual and a syntactical level. By means of this functionality we are able to provide further processing steps with correct and appropriate input. Furthermore, the visualization features enable users to validate or even generate hypotheses, as well as support the better understanding of medical text.
将概念从医学术语(如UMLS)映射到医学文档是许多(自动)处理文档任务的先决条件。由于UMLS的性质和完成映射的工具,实现正确和明确的映射并不总是可能的。这一缺点促使我们开发了一种编辑器,用于纠正所获得的信息。我们的编辑器MapFace将MetaMap Transfer (MMTx)程序接收到的信息可视化,并使用户能够在概念和语法层面上编辑和纠正这些信息。通过此功能,我们能够提供具有正确和适当输入的进一步处理步骤。此外,可视化功能使用户能够验证甚至生成假设,并支持更好地理解医学文本。
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引用次数: 2
Developing Competence Assessment Procedure for Spinal Anaesthesia 制定脊髓麻醉能力评估程序
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.25
Dajie Zhang, D. Albert, Cord Hockemeyer, D. Breen, Z. Kulcsár, G. Shorten, A. Aboulafia, E. Lövquist
Traditional approaches of assessment in the medical domain are insufficient for evaluating trainees' technical skills. Currently, many European medical training bodies are attempting to introduce competence-based training programmes for technical skills as well as other domains (e.g., communication, professional behaviour, clinical cognition). These efforts are limited due to the absence of appropriate assessment tools. Based on Competence-based Knowledge Space Theory (CbKST), a collaborative project MedCAP intends to develop a valid and reliable competence assessment procedure for one important medical skill, spinal anaesthesia. The paper briefly overviews the current states of training and assessment for medical procedural skills, describes the core ideas of CbKST, and introduces the ongoing project that will transfer the innovative approach of CbKST in personalized learning and competence assessment to the medical domain.
医学领域的传统评估方法不足以评估受训者的技术技能。目前,许多欧洲医疗培训机构正试图为技术技能以及其他领域(如沟通、专业行为、临床认知)引入基于能力的培训方案。由于缺乏适当的评估工具,这些努力受到限制。MedCAP是一个基于能力知识空间理论(CbKST)的合作项目,旨在为一项重要的医疗技能——脊髓麻醉——开发一种有效可靠的能力评估程序。本文简要概述了医疗程序技能培训和评估的现状,描述了CbKST的核心思想,并介绍了将CbKST在个性化学习和能力评估方面的创新方法转移到医学领域的正在进行的项目。
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引用次数: 11
Evaluating the Foot Electromyogram Signal as a Noise Reference for a Bathroom Scale Ballistocardiogram Recorder 评价足部肌电信号作为浴室式心电图仪的噪声参考
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.78
O. Inan, M. Etemadi, Richard M. Wiard, L. Giovangrandi, G. Kovacs
A bathroom scale ballistocardiogram (BCG) recorder has been developed in our group as a potential home monitor for heart failure outpatients. While the signal quality obtained by this device is as high as elaborate table- and bed-based BCG systems discussed previously in the literature, the standing posture required by this system may lead to undesired motion induced noise in the signal, particularly for elderly patients. Electromyogram (EMG) signals from the feet are proposed as a noise reference for the standing BCG measurement. The correlation between these signals and the BCG noise is quantified for a case with low (eyes open) and higher (eyes closed) involuntary movement on the scale. For the six subjects considered in this trial, the foot EMG appears to be a valuable reference for BCG movement noise estimation. Additionally, the fact that many bathroom scales have electrodes on the feet for various body fat percentage estimates makes the measurement highly practical for future implementations.
我们小组开发了一种浴室尺度的BCG记录仪,作为心力衰竭门诊患者的潜在家庭监护仪。虽然该装置获得的信号质量与先前文献中讨论的基于桌和床的卡卡苗系统一样高,但该系统所需的站立姿势可能导致信号中出现不希望的运动引起的噪声,特别是对于老年患者。来自足部的肌电图(EMG)信号被提议作为站立BCG测量的噪声参考。这些信号和卡介苗噪声之间的相关性被量化为低(睁眼)和高(闭眼)不自主运动的病例。对于本试验中考虑的六名受试者,足部肌电图似乎是BCG运动噪声估计的有价值参考。此外,许多浴室秤的脚上都有电极来估计不同的体脂百分比,这使得测量在未来的实施中非常实用。
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引用次数: 7
Towards Pervasive Health and Wellbeing Services 实现普及健康和福利服务
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.141
N. Saranummi
Summary form only given. Health services are today facing a number of interacting challenges. It is generally accepted that major, even radical, changes are required in health services to deliver better health outcomes at an affordable cost. IT is a change driver both in the horizontal and vertical directions. Horizontally we see the emergence and extension of a generic IT infrastructure that eventually will allow anytime, anywhere access to information and knowledge and context aware decision making. In the vertical direction IT enables a more effective and efficient health service environment. Standards and guidelines for an interoperable electronic patient record (EPR) have been developed and are today endorsed by industry and governments. Several countries are investing into a nation-wide "backbone" for health information and EPR exchange. The creation of the "backbone" allows separating data from processes. It's the processes (services) where the biggest potential and challenge is for improving the effectiveness and efficiency of health services. Another change driver is the expansion of (traditional) healthcare into a "health continuum" with the aim to engage and empower people to proactively manage their health and illness. This extends to the ageing people that can be assisted with tools and services to remain independent and integrated with the society. A third driver is the integration of medicine, life sciences, and engineering and physical sciences. These drivers point towards an application landscape that is characterized by "3 P's": pervasive, personal and personalized. In the keynote, we define what these three P's contain and how they relate to each other.
只提供摘要形式。今天,卫生服务面临着许多相互影响的挑战。人们普遍认为,要以负担得起的费用提供更好的健康结果,就需要对卫生服务进行重大甚至彻底的改革。IT在水平和垂直方向上都是一个变化驱动者。横向上,我们看到了通用IT基础设施的出现和扩展,它最终将允许随时随地访问信息和知识以及上下文感知决策。在垂直方向上,IT实现了更有效和高效的医疗服务环境。可互操作电子病历(EPR)的标准和指南已经制定出来,并得到了行业和政府的认可。一些国家正在投资建立一个全国性的卫生信息和EPR交换“骨干”。“主干”的创建允许从进程中分离数据。在这些过程(服务)中,最大的潜力和挑战在于提高卫生服务的效力和效率。另一个推动变革的因素是将(传统)医疗保健扩展为“健康连续体”,目的是让人们参与并赋予他们能力,主动管理自己的健康和疾病。这延伸到老年人,他们可以得到工具和服务的帮助,以保持独立和融入社会。第三个驱动因素是医学、生命科学、工程和物理科学的整合。这些驱动因素指向了一个以“3p”为特征的应用前景:普及、个性化和个性化。在主题演讲中,我们定义了这三个P所包含的内容以及它们之间的关系。
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引用次数: 2
Feature Selection by Lorentzian Peak Reconstruction for ^1NMR Post-Processing 核磁共振后处理中Lorentzian峰重构的特征选择
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.43
Hyung-Won Koh, S. Maddula, J. Lambert, R. Hergenröder, L. Hildebrand
In recent years, nuclear magnetic resonance spectroscopy (NMR) has become more and more popular in the field of metabolomic analysis. Analyzing and interpreting the obtained data is thus still challenging due to its complex and nontrivial characteristics. Further analysis of the obtained data is still mainly based on manual assignment, manual analysis and expert knowledge, and therefore time consuming. Common approaches towards automated post processing methods are often based on binning, which leads to loss of information in any case. This paper addresses an approach for reconstructing a one-dimensional NMR spectrum into a set of distinct lorentzian peak lines as an impressive feature selection and data reduction method and evaluates the performance on a real-world as well as on different simulated spectra.
近年来,核磁共振波谱(NMR)在代谢组学分析领域得到了越来越广泛的应用。因此,由于所获得的数据的复杂性和非平凡性,分析和解释仍然具有挑战性。对获得的数据的进一步分析仍然主要是基于人工分配、人工分析和专家知识,因此非常耗时。实现自动化后处理方法的常见方法通常基于分箱,这在任何情况下都会导致信息丢失。本文提出了一种将一维核磁共振谱重建为一组不同的洛伦兹峰线的方法,作为一种令人印象深刻的特征选择和数据简化方法,并评估了在现实世界以及不同的模拟光谱上的性能。
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引用次数: 6
A Gaussian Mixture Model Approach to Grouping Patients According to their Hospital Length of Stay 根据住院时间对患者进行分组的高斯混合模型方法
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.69
Revlin Abbi, E. El-Darzi, C. Vasilakis, P. Millard
In this paper we propose a new approach capable of determining clinically meaningful patient groups from a given dataset of patient spells. We hypothesise that the skewed distribution of length of stay (LOS) observations, often modelled in the past using mixed exponential equations, is composed of several homogeneous groups that together form the overall skewed LOS distribution. We show how the Gaussian mixture model (GMM) can be used to approximate each group, and discuss each group's possible clinical interpretation and statistical significance. In addition, we show how the health professional can use the outcome of the grouping approach to answer several questions about individual patients and their likely LOS in hospital. Our results demonstrate that the grouping of stroke patient spells estimated by the GMM resembles the clinical experience of stroke patients and the different stroke recovery patterns.
在本文中,我们提出了一种新的方法,能够从给定的患者法术数据集确定临床有意义的患者组。我们假设停留时间(LOS)观测值的偏态分布,通常在过去使用混合指数方程建模,是由几个同质组组成的,它们共同形成了总体的偏态LOS分布。我们展示了如何使用高斯混合模型(GMM)来近似每个组,并讨论了每个组可能的临床解释和统计意义。此外,我们还展示了卫生专业人员如何使用分组方法的结果来回答有关个别患者及其在医院可能的LOS的几个问题。研究结果表明,GMM估计的脑卒中患者病程分组与脑卒中患者的临床经验和不同的脑卒中恢复模式相似。
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引用次数: 11
Local Hölder Regularity-Based Modeling of RR Intervals 局部Hölder基于规则的RR区间建模
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.65
J. L. Véhel, O. Barrière
We analyze the local regularity of RR traces from ECG through the computation of the so-called Holder exponents. These exponents are at the basis of multifractal analysis, which has been shown to be relevant in the study of RR data. While multifractal analysis yields a global picture of the (statistical) distribution of regularity, we focus here on its time evolution. We show that this evolution is strongly correlated with the signal itself, a feature that seems to have remained unnoticed so far. We use this fact to build realistic synthetic RR traces.
我们通过计算所谓的霍尔德指数来分析ECG的RR迹线的局部正则性。这些指数是多重分形分析的基础,已被证明与RR数据的研究有关。虽然多重分形分析产生了规律性(统计)分布的全局图像,但我们在这里关注的是它的时间演变。我们表明,这种进化与信号本身密切相关,这一特征迄今为止似乎一直未被注意到。我们使用这个事实来构建真实的合成RR轨迹。
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引用次数: 16
Information Quality in Healthcare: Coherence of Data Compared between Organization's Electronic Patient Records 医疗保健中的信息质量:组织电子病历数据的一致性比较
Pub Date : 2008-06-17 DOI: 10.1109/CBMS.2008.64
M. Miettinen, Maritta Korhonen
In this paper we present a case-based analysis of health care data quality problems in a situation, where data of diabetes patient are combined from different information systems. Nationally uniform integrated health care information systems shall become more important when meeting the demands of patient centered care in the future. During the development of several electronic health records it has become clear that the integration of the data is still challenging. Data collected in various systems can have quality faults, it can for instance be non-coherent or include contradictory information, or the desired data is completely missing, as proved to be in our case as well. The quality of the content of patient information and the process of data production constitute a central part of good patient care, and more attention should be paid to them.
在本文中,我们提出了一种基于案例的分析,在一种情况下,糖尿病患者的数据从不同的信息系统相结合的卫生保健数据质量问题。为了满足未来以患者为中心的医疗需求,全国统一的综合医疗信息系统将变得更加重要。在一些电子健康记录的开发过程中,很明显,数据的整合仍然具有挑战性。在各种系统中收集的数据可能存在质量缺陷,例如,它可能不连贯或包含矛盾的信息,或者完全缺少所需的数据,正如在我们的案例中所证明的那样。患者信息内容的质量和数据生成的过程构成了良好的患者护理的核心部分,应该受到更多的关注。
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引用次数: 12
期刊
2008 21st IEEE International Symposium on Computer-Based Medical Systems
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