Pub Date : 2023-03-01DOI: 10.1007/s13670-023-00380-w
Berkley Davis, Katherina Y. Chen, Olivia Markert, J. Zillioux
{"title":"Anticholinergic Use for OAB in the Older Woman: An Update","authors":"Berkley Davis, Katherina Y. Chen, Olivia Markert, J. Zillioux","doi":"10.1007/s13670-023-00380-w","DOIUrl":"https://doi.org/10.1007/s13670-023-00380-w","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42613769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-07DOI: 10.1007/s13670-023-00379-3
M. O’Shea, C. Amundsen
{"title":"Neuromodulation in the Older Woman: An Advanced Treatment Option for Urgency Urinary Incontinence","authors":"M. O’Shea, C. Amundsen","doi":"10.1007/s13670-023-00379-3","DOIUrl":"https://doi.org/10.1007/s13670-023-00379-3","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43823892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose of review: This review article summarizes clinically and socially relevant developments over the past five years in the therapeutic use of the classical tryptamine psychedelic substance psilocybin, with respect to the common challenges faced by palliative care patients and their care teams. Psilocybin is available in whole fungal and isolated forms but is not yet approved for therapeutic use in the United States. Using targeted database and gray literature searches, and author recall, key sources were identified, reviewed, and synthesized as to the safety and efficacy of psilocybin in palliative care.
Recent findings: Life-threatening or life-limiting illnesses and faced by palliative care patients are comorbid with emotional and spiritual distress. Research and field reports reviewed suggest that psilocybin has significant and in some cases, sustained anxiolytic, antidepressant, anti-inflammatory and entheogenic effects with a favorable safety profile. Limitations of the research include the risk for selection bias toward healthy, white, financially privileged individuals, and in general, follow-up timelines too short to appropriately evaluate durability of outcomes in psychospiritual benefits and quality of life.
Summary: While more research is needed for palliative care populations specifically, reasonable inferences can be made regarding the potential for benefit to palliative care patients from psilocybin's demonstrated anxiolytic, antidepressant, anti-inflammatory and entheogenic effects. However, major legal, ethical and financial barriers to access exist for the general population; obstacles which are likely worsened for geriatric and palliative care patients. Empiric treatment and large-scale controlled trials of psilocybin should be conducted to further investigate the findings of the smaller studies reviewed here across a variety of populations, for a greater understanding of therapeutic benefit and clinically relevant safety criteria, and to support thoughtful legalization and medical access.
{"title":"Psilocybin in Palliative Care: An Update.","authors":"Emily Whinkin, Moira Opalka, Conor Watters, Atara Jaffe, Sunil Aggarwal","doi":"10.1007/s13670-023-00383-7","DOIUrl":"10.1007/s13670-023-00383-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review article summarizes clinically and socially relevant developments over the past five years in the therapeutic use of the classical tryptamine psychedelic substance psilocybin, with respect to the common challenges faced by palliative care patients and their care teams. Psilocybin is available in whole fungal and isolated forms but is not yet approved for therapeutic use in the United States. Using targeted database and gray literature searches, and author recall, key sources were identified, reviewed, and synthesized as to the safety and efficacy of psilocybin in palliative care.</p><p><strong>Recent findings: </strong>Life-threatening or life-limiting illnesses and faced by palliative care patients are comorbid with emotional and spiritual distress. Research and field reports reviewed suggest that psilocybin has significant and in some cases, sustained anxiolytic, antidepressant, anti-inflammatory and entheogenic effects with a favorable safety profile. Limitations of the research include the risk for selection bias toward healthy, white, financially privileged individuals, and in general, follow-up timelines too short to appropriately evaluate durability of outcomes in psychospiritual benefits and quality of life.</p><p><strong>Summary: </strong>While more research is needed for palliative care populations specifically, reasonable inferences can be made regarding the potential for benefit to palliative care patients from psilocybin's demonstrated anxiolytic, antidepressant, anti-inflammatory and entheogenic effects. However, major legal, ethical and financial barriers to access exist for the general population; obstacles which are likely worsened for geriatric and palliative care patients. Empiric treatment and large-scale controlled trials of psilocybin should be conducted to further investigate the findings of the smaller studies reviewed here across a variety of populations, for a greater understanding of therapeutic benefit and clinically relevant safety criteria, and to support thoughtful legalization and medical access.</p>","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9674767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-22DOI: 10.1007/s13670-022-00378-w
Ryan C. Martin
{"title":"Disparities in Heart Failure Management in Older Adults","authors":"Ryan C. Martin","doi":"10.1007/s13670-022-00378-w","DOIUrl":"https://doi.org/10.1007/s13670-022-00378-w","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46771737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1007/s13670-022-00377-x
S. Durso
{"title":"The 4 M’s: What Every Specialist Should Know","authors":"S. Durso","doi":"10.1007/s13670-022-00377-x","DOIUrl":"https://doi.org/10.1007/s13670-022-00377-x","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41910783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-04DOI: 10.1007/s13670-022-00376-y
P. Roy, K. Walsh, Z. Goldberger
{"title":"An Approach to Cardiac Syncope in the Elderly Patient","authors":"P. Roy, K. Walsh, Z. Goldberger","doi":"10.1007/s13670-022-00376-y","DOIUrl":"https://doi.org/10.1007/s13670-022-00376-y","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44906666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.1007/s13670-022-00375-z
I. Meyer, H. Richter
{"title":"Challenges and New Insights in the Management of Urinary Incontinence in Older Women","authors":"I. Meyer, H. Richter","doi":"10.1007/s13670-022-00375-z","DOIUrl":"https://doi.org/10.1007/s13670-022-00375-z","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43405198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-12DOI: 10.1007/s13670-022-00374-0
Priyanka T Bhattacharya, M. Maurer, Dia A Smiley
{"title":"Amyloid Cardiomyopathy in Older Adults","authors":"Priyanka T Bhattacharya, M. Maurer, Dia A Smiley","doi":"10.1007/s13670-022-00374-0","DOIUrl":"https://doi.org/10.1007/s13670-022-00374-0","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48093255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1007/s13670-021-00373-7
Tyler J. Jones, Bishwajit Bhattacharya, K. Davis
{"title":"Optimizing Cardiac Performance During the Perioperative Period","authors":"Tyler J. Jones, Bishwajit Bhattacharya, K. Davis","doi":"10.1007/s13670-021-00373-7","DOIUrl":"https://doi.org/10.1007/s13670-021-00373-7","url":null,"abstract":"","PeriodicalId":38089,"journal":{"name":"Current Geriatrics Reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41656846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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