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Expert knowledge-based peak current mode control of electrosurgical generators for improved output power regulation. 基于专家知识的电外科发电机峰值电流模式控制,以改善输出功率调节。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-11-17 eCollection Date: 2023-01-01 DOI: 10.2478/joeb-2023-0005
Muhammad Mohsin Rafiq, Asier Ibeas, Nasim Ullah

Electrosurgical generators (ESG) are widely used in medical procedures to cut and coagulate tissue. Accurate control of the output power is crucial for surgical success, but can be challenging to achieve. In this paper, a novel expert knowledge-based peak current mode controller (EK-PCMC) is proposed to regulate the output power of an ESG. The EK-PCMC leverages expert knowledge to adapt to changes in tissue impedance during surgical procedures. We compared the performance of the EK-PCMC with the classical peak current mode controller (PCMC) and fuzzy PID controller. The results demonstrate that the EK-PCMC significantly outperformed the PCMC, reducing the integral square error (ISE) and integral absolute error (IAE) by a factor of 3.88 and 4.86, respectively. In addition, the EK-PCMC outperformed the fuzzy PID controller in terms of transient response and steady-state performance. Our study highlights the effectiveness of the proposed EK-PCMC in improving the regulation of the output power of an ESG and improving surgical outcomes.

电外科发电机(ESG)广泛应用于切割和凝固组织的医疗程序中。准确控制输出功率对手术成功至关重要,但很难实现。本文提出了一种基于专家知识的峰值电流模式控制器(EK-PCMC)来调节ESG的输出功率。EK-PCMC利用专业知识来适应外科手术过程中组织阻抗的变化。我们将EK-PCMC与经典的峰值电流模式控制器(PCMC)和模糊PID控制器的性能进行了比较。结果表明,EK-PCMC显著优于PCMC,将积分平方误差(ISE)和积分绝对误差(IAE)分别降低了3.88和4.86倍。此外,EK-PCMC在瞬态响应和稳态性能方面都优于模糊PID控制器。我们的研究强调了提出的EK-PCMC在改善ESG输出功率调节和改善手术结果方面的有效性。
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引用次数: 0
A renewed challenge to electrical bioimpedance: rapid assessment of pathogenic bacteria. 电生物阻抗的新挑战:致病菌的快速评估。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-03-01 DOI: 10.2478/joeb-2023-0001
Eugen Gheorghiu
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引用次数: 2
A High Accuracy Voltage Approximation Model Based on Object-oriented Sensitivity Matrix Estimation (OO-SME Model) in Electrical Impedance Tomography. 基于面向对象灵敏度矩阵估计(OO-SME 模型)的电阻抗断层扫描高精度电压逼近模型
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-01-08 eCollection Date: 2022-01-01 DOI: 10.2478/joeb-2022-0015
Zengfeng Gao, Panji Nursetia Darma, Daisuke Kawashima, Masahiro Takei

The image reconstruction in electrical impedance tomography (EIT) has low accuracy due to the approximation error between the measured voltage change and the approximated voltage change, from which the object cannot be accurately reconstructed and quantitatively evaluated. A voltage approximation model based on object-oriented sensitivity matrix estimation (OO-SME model) is proposed to reconstruct the image with high accuracy. In the OO-SME model, a sensitivity matrix of the object-field is estimated, and the sensitivity matrix change from the background-field to the object-field is estimated to optimize the approximated voltage change, from which the approximation error is eliminated to improve the reconstruction accuracy. Against the existing linear and nonlinear models, the approximation error in the OO-SME model is eliminated, thus an image with higher accuracy is reconstructed. The simulation shows that the OO-SME model reconstructs a more accurate image than the existing models for quantitative evaluation. The relative accuracy (RA) of reconstructed conductivity is increased up to 83.98% on average. The experiment of lean meat mass evaluation shows that the RA of lean meat mass is increased from 7.70% with the linear model to 54.60% with the OO-SME model. It is concluded that the OO-SME model reconstructs a more accurate image to evaluate the object quantitatively than the existing models.

电阻抗断层成像(EIT)中的图像重建精度较低,原因是测量电压变化与近似电压变化之间存在近似误差,无法从中准确重建和定量评估对象。为了高精度地重建图像,我们提出了一种基于面向对象灵敏度矩阵估计的电压近似模型(OO-SME 模型)。在 OO-SME 模型中,估算对象场的灵敏度矩阵,并估算从背景场到对象场的灵敏度矩阵变化,以优化近似电压变化,从而消除近似误差,提高重建精度。与现有的线性和非线性模型相比,OO-SME 模型消除了近似误差,因此能重建出精度更高的图像。模拟结果表明,在定量评估方面,OO-SME 模型重建的图像比现有模型更精确。重建电导率的相对准确度(RA)平均提高了 83.98%。瘦肉质量评价实验表明,瘦肉质量的相对准确率从线性模型的 7.70% 提高到 OO-SME 模型的 54.60%。由此得出结论,OO-SME 模型比现有模型能重建更精确的图像,对物体进行定量评估。
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引用次数: 0
A fresh look at sports PSM-systems. 重新审视体育psm系统。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-01-01 DOI: 10.2478/joeb-2023-0003
Vladimir Savostyanov, Alexander Kobelev, Anton Govorin

The aim of the proposed study is to reveal the correlations between the dynamics of Respiratory Rate (RR) and Heart Rate (HR) during intermittent physical work at maximum power on a cycle ergometer. The stage of investigating the General functional athlete readiness (GFAR) was conducted using the sports standard "R-Engine" and the cycle ergometer in 16 volunteers (10 men, 6 women) whose average age was 21±1.17 years. To determine the athletic potential of the volunteers in this study, we used our own Coefficient of Anaerobic Capacity (CANAC Q, beats). Continuous registration of the heart rate and respiratory rate of volunteers in the maximum power sports test was performed by the "RheoCardioMonitor" system with a module of the athlete functional readiness based on the method of Transthoracic electrical impedance rheography (TEIRG). The degree of correlation of functional indicators (M, HRM, GFAR) with CANAC Q in all experimental series of the study group as a whole (n=80) was at a very high level, which confirmed the effectiveness of using the Coefficient of Anaerobic Capacity (CANAC Q) in assessing the general functional athlete readiness of the volunteers. CANAC Q is measured in "beats" of the heart and is recorded very accurately using the method of transthoracic electrical impedance rheography (TEIRG). For this reason, as a promising sports PSM-system, CANAC Q can replace the methods for determining the functional athlete readiness by blood lactate concentration and maximum oxygen consumption.

这项研究的目的是揭示呼吸率(RR)和心率(HR)动态之间的相关性在间歇体力工作在最大功率上的循环计力器。采用运动标准“R-Engine”和自行车测力仪对16名平均年龄为21±1.17岁的志愿者(男10名,女6名)进行GFAR(一般功能运动员准备状态)调查。为了确定本研究中志愿者的运动潜力,我们使用了我们自己的无氧能力系数(CANAC Q,节拍)。采用基于经胸电阻抗流变学(TEIRG)方法的运动员功能准备模块“RheoCardioMonitor”系统对最大功率运动试验中志愿者的心率和呼吸速率进行连续登记。在整个研究组(n=80)的所有实验系列中,功能指标(M、HRM、GFAR)与CANAC Q的相关程度都处于非常高的水平,这证实了使用无氧能力系数(Coefficient of厌氧能力,CANAC Q)来评估志愿者一般功能运动员准备状态的有效性。CANAC Q以心脏的“节拍”来测量,并使用经胸电阻抗流变学(TEIRG)方法非常准确地记录下来。因此,CANAC Q作为一种很有发展前景的运动psm系统,可以取代血乳酸浓度和最大耗氧量测定运动员机能状态的方法。
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引用次数: 0
Evaluation of novel beverage formulations for hydration enhancement in humans. 新型人体补水饮料配方的评价。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-01-01 DOI: 10.2478/joeb-2023-0002
Grant M Tinsley, Madelin R Siedler, Christian Rodriguez, Patrick S Harty, Matthew T Stratton, Sarah J White, Dale S Keith, Jacob J Green, Jake R Boykin, Abegale D Williams, Brielle DeHaven, Alexandra Brojanac, Ethan Tinoco

This study evaluated the influence of novel beverage formulations on bioimpedance- and urine-based hydration markers. Thirty young healthy adults (n=16 females, n=14 males; age: 23.2±3.7 years; BMI: 24.3±3.3 kg/m2) participated in a randomized, double-blind, placebo-controlled, crossover study. Participants completed three conditions with baseline bioimpedance, urine, and body mass assessments, followed by ingestion of one liter of a test beverage over a 30-minute period. The three beverages were: active hydration formulation in still (AFstill) or sparkling (AFspark) water and a still water control. The active formulations were identical in concentrations of alpha-cyclodextrin and complexing agents. Following beverage ingestion, bioimpedance assessments were performed every 15 minutes for two hours, followed by final urinary and body mass assessments. The primary bioimpedance outcomes were phase angle at 50 kHz, resistance of the extra-cellular compartment (R0), and resistance of the intracellular compartment (Ri). Data were analyzed using linear mixed effects models, Friedman tests, and Wilcoxon tests. Statistically significant changes in phase angle values were observed at 30 (p=0.004) and 45 minutes (p=0.024) following the initiation of beverage ingestion in the AFstill condition as compared to the reference model (i.e., control condition at baseline). Although differences between conditions were not statistically significant at later time points, the data were consistent with AFstill having greater elevations in phase angle throughout the monitoring period. At the 30-minute time point only, statistically significant differences in R0 for AFspark (p<0.001) and in Ri for AFstill (p=0.008) were observed. When averaged across post-ingestion time points, there was a trend (p=0.08) for Ri differences between conditions. The net fluid balance was greater than zero, indicating retention of ingested fluid, for AFstill (p=0.02) and control (p=0.03), with a trend for AFspark (p=0.06). In conclusion, an active formulation containing alpha-cyclodextrin in still water demonstrated potential benefits for enhancing hydration markers in humans.

本研究评估了新型饮料配方对生物阻抗和尿液水合指标的影响。30名年轻健康成人(女性16名,男性14名;年龄:23.2±3.7岁;BMI: 24.3±3.3 kg/m2)参加了一项随机、双盲、安慰剂对照的交叉研究。参与者完成了三个条件,包括基线生物阻抗、尿液和体重评估,然后在30分钟内饮用一升测试饮料。这三种饮料是:在静止(AFstill)或气泡(AFspark)水中的活性水合制剂和静止水对照。活性配方中-环糊精和络合剂的浓度相同。饮用饮料后,每15分钟进行一次生物阻抗评估,持续2小时,随后进行最终尿液和体重评估。主要的生物阻抗结果是50 kHz时的相位角、细胞外室的电阻(R0)和细胞内室的电阻(Ri)。数据分析采用线性混合效应模型、Friedman检验和Wilcoxon检验。与参考模型(即基线的对照条件)相比,在AFstill条件下开始饮用饮料后30分钟(p=0.004)和45分钟(p=0.024),相角值的变化具有统计学意义。虽然在后期的时间点上,不同条件之间的差异没有统计学意义,但数据与afl在整个监测期间仍然有较大的相位角升高一致。仅在30分钟时间点,AFspark的R0差异具有统计学意义(p
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引用次数: 0
Skin layer classification by feedforward neural network in bioelectrical impedance spectroscopy. 生物电阻抗谱中前馈神经网络的皮肤层分类。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-01-01 DOI: 10.2478/joeb-2023-0004
Kiagus Aufa Ibrahim, Marlin Ramadhan Baidillah, Ridwan Wicaksono, Masahiro Takei

Conductivity change in skin layers has been classified by source indicator ok (k=1: Stratum corneum, k=2: Epidermis, k=3: Dermis, k=4: Fat, and k=5: Stratum corneum + Epidermis) trained from feedforward neural network (FNN) in bioelectrical impedance spectroscopy (BIS). In BIS studies, treating the skin as a bulk, limits the differentiation of conductivity changes in individual skin layers, however skin layer classification using FNN shows promise in accurately categorizing skin layers, which is essential for predicting source indicators ok and initiating skin dielectric characteristics diagnosis. The ok is trained by three main conceptual points which are (i) implementing FNN for predicting k in conductivity change, (ii) profiling four impedance inputs αξ consisting of magnitude input α|z|, phase angle input αθ, resistance input αR, and reactance input αx for filtering nonessential input, and (iii) selecting low and high frequency pair (frlh) by distribution of relaxation time (DRT) for eliminating parasitic noise effect. The training data set of FNN is generated to obtain the αξR10×17×10 by 10,200 cases by simulation under configuration and measurement parameters. The trained skin layer classification is validated through experiments with porcine skin under various sodium chloride (NaCl) solutions CNaCl = {15, 20, 25, 30, 35}[mM] in the dermis layer. FNN successfully classified conductivity change in the dermis layer from experiment with accuracy of 90.6% for the bipolar set-up at f6lh=10&100[kHz] and with the same accuracy for the tetrapolar at f8lh=35&100[kHz]. The measurement noise and systematic error in the experimental results are minimized by the proposed method using the feature extraction based on αξ at frlh.

利用生物电阻抗谱(BIS)中的前馈神经网络(FNN)训练的源指标ok (k=1:角质层,k=2:表皮,k=3:真皮,k=4:脂肪,k=5:角质层+表皮)对皮肤各层电导率变化进行了分类。在BIS研究中,将皮肤视为一个整体,限制了单个皮肤层电导率变化的区分,然而,使用FNN的皮肤层分类在准确分类皮肤层方面显示出希望,这对于预测源指标和启动皮肤介电特性诊断至关重要。ok由三个主要概念点进行训练,即(i)实现FNN以预测电导率变化中的k, (ii)绘制四个阻抗输入αξ,包括幅度输入α|z|,相角输入αθ,电阻输入α r和电抗输入αx,用于滤波非必要输入,以及(iii)通过弛豫时间(DRT)分布选择低频和高频对(frlh)以消除寄生噪声效应。在配置参数和测量参数下,通过10200例的仿真,生成FNN的训练数据集,得到αξ∈R10×17×10。在真皮层不同氯化钠(NaCl)溶液CNaCl = {15, 20, 25, 30, 35}[mM]下,以猪皮肤为实验对象,验证训练后的皮肤层分类方法。FNN成功地对实验中真皮层的电导率变化进行了分类,在f6lh=10 &100 [kHz]时,双极设置的准确率为90.6%,在f8lh=35 &100 [kHz]时,四极设置的准确率也相同。该方法利用基于αξ值frlh的特征提取,将实验结果中的测量噪声和系统误差降至最低。
{"title":"Skin layer classification by feedforward neural network in bioelectrical impedance spectroscopy.","authors":"Kiagus Aufa Ibrahim,&nbsp;Marlin Ramadhan Baidillah,&nbsp;Ridwan Wicaksono,&nbsp;Masahiro Takei","doi":"10.2478/joeb-2023-0004","DOIUrl":"https://doi.org/10.2478/joeb-2023-0004","url":null,"abstract":"<p><p>Conductivity change in skin layers has been classified by source indicator <i>o<sup>k</sup></i> (<i>k</i>=1: Stratum corneum, <i>k</i>=2: Epidermis, <i>k</i>=3: Dermis, <i>k</i>=4: Fat, and <i>k</i>=5: Stratum corneum + Epidermis) trained from feedforward neural network (FNN) in bioelectrical impedance spectroscopy (BIS). In BIS studies, treating the skin as a bulk, limits the differentiation of conductivity changes in individual skin layers, however skin layer classification using FNN shows promise in accurately categorizing skin layers, which is essential for predicting source indicators <i>o<sup>k</sup></i> and initiating skin dielectric characteristics diagnosis. The <i>o<sup>k</sup></i> is trained by three main conceptual points which are (i) implementing FNN for predicting <i>k</i> in conductivity change, (ii) profiling four impedance inputs <i>α<sub>ξ</sub></i> consisting of magnitude input <i>α</i>|<sub><i>z</i></sub>|, phase angle input <i>α<sub>θ</sub></i>, resistance input <i>α<sub>R</sub></i>, and reactance input <i>α<sub>x</sub></i> for filtering nonessential input, and (iii) selecting low and high frequency pair <math><mrow><mrow><mo>(</mo><mrow><msubsup><mi>f</mi><mi>r</mi><mrow><mi>l</mi><mi>h</mi></mrow></msubsup></mrow><mo>)</mo></mrow></mrow></math> by distribution of relaxation time (DRT) for eliminating parasitic noise effect. The training data set of FNN is generated to obtain the <i>α<sub>ξ</sub></i> ∈ <i><b>R</b></i><sup>10×17×10</sup> by 10,200 cases by simulation under configuration and measurement parameters. The trained skin layer classification is validated through experiments with porcine skin under various sodium chloride (NaCl) solutions <i>C<sub>NaCl</sub></i> = {15, 20, 25, 30, 35}[mM] in the dermis layer. FNN successfully classified conductivity change in the dermis layer from experiment with accuracy of 90.6% for the bipolar set-up at <math><mrow><msubsup><mi>f</mi><mn>6</mn><mrow><mi>l</mi><mi>h</mi></mrow></msubsup><mo>=</mo><mn>10</mn><mtext> </mtext><mo>&</mo><mn>100</mn><mtext> </mtext><mo>[</mo><mtext>kHz]</mtext></mrow></math> and with the same accuracy for the tetrapolar at <math><mrow><msubsup><mi>f</mi><mn>8</mn><mrow><mi>l</mi><mi>h</mi></mrow></msubsup><mo>=</mo><mn>35</mn><mtext> </mtext><mo>&</mo><mn>100</mn><mtext> </mtext><mo>[</mo><mtext>kHz]</mtext></mrow></math>. The measurement noise and systematic error in the experimental results are minimized by the proposed method using the feature extraction based on <i>α<sub>ξ</sub></i> at <math><mrow><msubsup><mi>f</mi><mi>r</mi><mrow><mi>l</mi><mi>h</mi></mrow></msubsup></mrow></math>.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"14 1","pages":"19-31"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive Biotechnical System for Screening Risk-based Diagnosis of COVID-19 and Post-COVID Syndrome. 基于风险诊断的COVID-19和COVID-19后综合征筛查综合生物技术系统
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-09-09 eCollection Date: 2022-01-01 DOI: 10.2478/joeb-2022-0008
Vladimir Savostyanov, Alexander Kobelev, Ivan Kudashov

At present, there are no hardware or biochemical systems that allow to assess the severity of post-COVID syndrome in vivo. The hardware of the proposed biotechnical system is based on routine transthoracic electrical impedance rheography, which makes it possible to register the frequency characteristics of the patient's bioimpedance response to controlled stress stimulation, thereby simultaneously fixing the characteristics of his productive heart, the state of the hemomicrocirculatory bed, the efficiency of the gas transport function of his blood, and also reliably assess personal reactivity and adaptive potential. Subsequent mathematical approximation of the obtained biometric data by an original neural network makes it possible to rank the results obtained and automatically generate a program of medical rehabilitation for a particular patient, depending on the severity of his post-COVID syndrome. The study results proved two reliable physiological signs confirming the presence of latent post-COVID complications: a decrease in the base impedance value for light exercise and an increase in the length of the systolic arc of the rheocardiogram.

目前,还没有硬件或生化系统可以在体内评估covid - 19后综合征的严重程度。所提出的生物技术系统的硬件是基于常规经胸电阻抗流变学,这使得记录患者对受控应激刺激的生物阻抗反应的频率特性成为可能,从而同时固定他的生产心脏的特性、血液微循环床的状态、血液的气体输送功能的效率、并可靠地评估个人的反应能力和适应潜力。随后,通过原始神经网络对获得的生物特征数据进行数学近似,可以对获得的结果进行排序,并根据特定患者后冠状病毒综合征的严重程度自动生成医疗康复计划。研究结果证实了两个可靠的生理信号,证实了潜在的covid - 19后并发症的存在:轻度运动时的基础阻抗值下降和收缩弧长度增加。
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引用次数: 0
Body Composition Changes in the Immediate Peri-operative Period Following Total Joint Arthroplasty. 全关节置换术后围手术期身体成分的变化。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-09-09 eCollection Date: 2022-01-01 DOI: 10.2478/joeb-2022-0007
Michael C Marinier, Ayobami S Ogunsola, Jacob M Elkins

Background: Bioimpedance analysis (BIA) is a readily available tool to assess body composition in a clinical setting. BIA has received little attention in orthopaedics and namely joint arthroplasty. This study aims to quantify changes in body composition in the immediate peri-operative period following total joint arthroplasty.

Methods: Adults scheduled for elective total joint arthroplasty were recruited to participate. Patients underwent BIA scans in the immediate peri-operative period: pre-operative on their day of surgery, post-operative day 0, and post-operative day 1.

Results: 67 patients were enrolled to undergo BIA scans. Mean age was 62.64 ± 10.28 years old, and 49.2% were females. The all-supine cohort exhibited a 0.36 ± 0.61 kg increase in dry lean mass (p < 0.001) and 1.30 ± 2.14 kg increase in lean body mass on postoperative day 0 (p < 0.001). Patients received to 1.16 ± 0.58 kg of fluid mass, on average.

Conclusion: BIA is a rapid, portable tool that allows for body composition analysis of an inpatient surgical population. This study demonstrated that BIA can detect net fluid changes and may approximate implant mass following total joint arthroplasty. This may aid surgeons in interpreting post-operative body composition changes.

背景:生物阻抗分析(BIA)是一种在临床环境中评估身体成分的现成工具。BIA在骨科,即关节置换术中很少受到关注。本研究旨在量化全关节置换术后围手术期身体成分的变化。方法:招募计划进行选择性全关节置换术的成年人参与。患者在围手术期接受BIA扫描:术前,术后第0天,术后第1天。结果:67例患者入组接受BIA扫描。平均年龄62.64±10.28岁,女性占49.2%。全仰卧组术后第0天干瘦体重增加0.36±0.61 kg (p < 0.001),瘦体重增加1.30±2.14 kg (p < 0.001)。患者接受的液体质量平均为1.16±0.58 kg。结论:BIA是一种快速、便携的工具,可用于住院外科患者的身体成分分析。本研究表明,BIA可以检测全关节置换术后的净液体变化,并可以近似地估计种植体质量。这可能有助于外科医生解释术后身体成分的变化。
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引用次数: 0
Bioelectrical Impedance Changes of the Trunk are Opposite the Limbs Following Acute Hydration Change. 急性水合变化后躯干的生物电阻抗变化与四肢相反。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-06-25 eCollection Date: 2022-01-01 DOI: 10.2478/joeb-2022-0005
Dale R Wagner

This study aimed to evaluate the changes in impedance and estimates of body composition variables obtained from segmental multi-frequency bioelectrical impedance analysis (SMFBIA) following acute hydration change. All participants (N = 11 active adults) had SMFBIA measurements at baseline (euhydration), post-dehydration, and post-hyperhydration in an experimental repeated-measures design. Dehydration and hyperhydration trials were randomized with the opposite treatment given 24 h later. Dehydration was achieved via a heat chamber of 40 °C and 60% relative humidity. Hyperhydration was achieved by drinking lightly-salted water (30 mmol·L-1 NaCl; 1.76 g NaCl·L-1) within 30 min. Post-measurements were taken 30 min after each treatment. Despite changes in mass post-dehydration (Δ = -2.0%, p < 0.001) and post-hyperhydration (Δ = 1.2%, p < 0.001), SMFBIA estimates of total body water (TBW) did not change significantly across trials (p = 0.507), leading to significant differences (p < 0.001) in SMFBIA-estimates of body fat percentage across trials. Dehydration resulted in a significant (p < 0.001) 8% decrease in limb impedances at both 20 kHz and 100 kHz. Hyperhydration increased limb impedances only slightly (1.5%, p > 0.05). Impedance changes in the trunk followed an opposite pattern of the limbs. SMFBIA failed to track acute changes in TBW. Divergent impedance changes suggest the trunk is influenced by fluid volume, but the limbs are influenced by ion concentration.

本研究旨在评估急性水合变化后阻抗的变化,并通过分段多频生物电阻抗分析(SMFBIA)估计身体成分变量。在实验重复测量设计中,所有参与者(N = 11名活跃的成年人)在基线(未水化)、脱水后和过度水化后进行SMFBIA测量。脱水和水合过度试验随机进行,24小时后给予相反的治疗。脱水通过40°C和60%相对湿度的热室实现。通过饮用淡盐水(30 mmol·L-1 NaCl;1.76 g NaCl·L-1),每次处理后30 min进行后测。尽管脱水后的体重(Δ = -2.0%, p < 0.001)和过度水合后的体重(Δ = 1.2%, p < 0.001)发生了变化,但SMFBIA对全身水分(TBW)的估计值在各试验之间没有显著变化(p = 0.507),导致SMFBIA对体脂率的估计值在各试验之间存在显著差异(p < 0.001)。脱水导致肢体阻抗在20 kHz和100 kHz显著(p < 0.001)下降8%。高水合仅使肢体阻抗增加1.5%,p > 0.05。躯干的阻抗变化与四肢相反。SMFBIA未能追踪TBW的急性变化。发散性阻抗变化提示主干受液体体积影响,而四肢受离子浓度影响。
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引用次数: 1
Validation of Non-empirical Fat-free Mass Estimation Model for a Wrist-worn Device. 腕戴式设备非经验无脂质量估计模型的验证。
Q3 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-06-25 eCollection Date: 2022-01-01 DOI: 10.2478/joeb-2022-0006
Aleksandr Polokhin, Anna Pronina, Andrey Boev, Stas Gorbunov

Fat-free mass (FFM) estimation has dramatic importance for body composition evaluation, often providing a basis for treatment of obesity and muscular dystrophy. However, current methods of FFM estimation have several drawbacks, usually related to either cost-effectiveness and equipment size (dual-energy X-ray absorptiometry (DEXA) scan) or model limitations. In this study, we present and validate a new FFM estimation model based on hand-to-hand bioimpedance analysis (BIA) and arm volume. Forty-two participants underwent a full-body DEXA scan, a series of anthropometric measurements, and upper-body BIA measurements with the custom-designed wearable wrist-worn impedance meter. A new two truncated cones (TTC) model was trained on DEXA data and achieved the best performance metrics of 0.886 ± 0.051 r2, 0.052 ± 0.009 % mean average error, and 6.884 ± 1.283 kg maximal residual error in FFM estimation. The model further demonstrated its effectiveness in Bland-Altman comparisons with the skinfold thickness-based FFM estimation method, achieving the least mean bias (0.007 kg). The novel TTC model can provide an alternative to full-body BIA measurements, demonstrating an accurate FFM estimation independently of population variables.

无脂质量(Fat-free mass, FFM)估算对于身体成分评估具有重要意义,通常为肥胖和肌肉萎缩症的治疗提供依据。然而,目前的FFM估计方法有几个缺点,通常与成本效益和设备尺寸(双能x射线吸收仪(DEXA)扫描)或模型限制有关。在这项研究中,我们提出并验证了一个新的基于手对手生物阻抗分析(BIA)和手臂体积的FFM估计模型。42名参与者接受了全身DEXA扫描,一系列人体测量,以及定制设计的可穿戴式腕带阻抗计的上半身BIA测量。在DEXA数据上训练新的两截锥(two truncated cones, TTC)模型,在FFM估计中获得了0.886±0.051 r2、0.052±0.009%均值误差和6.884±1.283 kg最大残差的最佳性能指标。与基于皮褶厚度的FFM估计方法相比,该模型在Bland-Altman比较中进一步证明了其有效性,实现了最小的平均偏差(0.007 kg)。新的TTC模型可以替代全身BIA测量,证明了独立于种群变量的准确FFM估计。
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引用次数: 0
期刊
Journal of Electrical Bioimpedance
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