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Naegleria: a classic model for de novo basal body assembly Naegleria:从头开始的基础体组装的经典模型
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-04-04 DOI: 10.1186/s13630-016-0032-6
Lillian K. Fritz-Laylin, C. Fulton
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引用次数: 13
Basal bodies across eukaryotes series: basal bodies in the freshwater planarian Schmidtea mediterranea 跨真核生物系列的基底:地中海淡水拟涡虫中的基底
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-03-19 DOI: 10.1186/s13630-016-0037-1
J. Azimzadeh, C. Basquin
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引用次数: 13
Human basal body basics. 人体基础知识。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-03-14 eCollection Date: 2016-01-01 DOI: 10.1186/s13630-016-0030-8
Anastassiia Vertii, Hui-Fang Hung, Heidi Hehnly, Stephen Doxsey

In human cells, the basal body (BB) core comprises a ninefold microtubule-triplet cylindrical structure. Distal and subdistal appendages are located at the distal end of BB, where they play indispensable roles in cilium formation and function. Most cells that arrest in the G0 stage of the cell cycle initiate BB docking at the plasma membrane followed by BB-mediated growth of a solitary primary cilium, a structure required for sensing the extracellular environment and cell signaling. In addition to the primary cilium, motile cilia are present in specialized cells, such as sperm and airway epithelium. Mutations that affect BB function result in cilia dysfunction. This can generate syndromic disorders, collectively called ciliopathies, for which there are no effective treatments. In this review, we focus on the features and functions of BBs and centrosomes in Homo sapiens.

在人体细胞中,基质体(BB)核心由九重微管三联体圆柱结构组成。远端和亚远端附属物位于基质体的远端,它们在纤毛形成和功能中发挥着不可或缺的作用。大多数停滞在细胞周期 G0 阶段的细胞在质膜上对接 BB 后,由 BB 介导的单生初级纤毛的生长。除了初级纤毛外,精子和气道上皮细胞等特化细胞中也存在运动纤毛。影响 BB 功能的突变会导致纤毛功能障碍。这可能导致综合症,统称为纤毛疾病,目前尚无有效的治疗方法。在这篇综述中,我们将重点讨论智人中 BB 和中心体的特征和功能。
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引用次数: 0
Basal body structure in Trichonympha 毛管菌的基体结构
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-03-01 DOI: 10.1186/s13630-016-0031-7
P. Guichard, P. Gönczy
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引用次数: 6
Measuring the primary cilium length: improved method for unbiased high-throughput analysis 测定初级纤毛长度:无偏高通量分析的改进方法
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-11 DOI: 10.1186/s13630-016-0028-2
Anneloes Dummer, C. Poelma, M. DeRuiter, M. Goumans, B. Hierck
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引用次数: 60
Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei 布鲁氏锥虫的基本体结构和细胞周期依赖性生物发生
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-08 DOI: 10.1186/s13630-016-0023-7
S. Vaughan, K. Gull
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引用次数: 36
Paramecium tetraurelia basal body structure 四毛草履虫的基体结构
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-08 DOI: 10.1186/s13630-016-0026-4
A. Tassin, M. Lemullois, A. Aubusson-Fleury
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引用次数: 31
Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium 顶复虫、弓形虫和疟原虫的基础体结构和组成
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-04 DOI: 10.1186/s13630-016-0025-5
M. Francia, J. Dubremetz, N. Morrissette
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引用次数: 47
Basal bodies in Xenopus 爪蟾的基体
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-03 DOI: 10.1186/s13630-016-0024-6
Siwei Zhang, B. Mitchell
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引用次数: 17
Cilia in autophagy and cancer 纤毛在自噬和癌症中的作用
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2016-02-03 DOI: 10.1186/s13630-016-0027-3
Muqing Cao, Q. Zhong
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引用次数: 41
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