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Flow-diverter stents alone and in combination with coiling as treatment options for unruptured, symptomatic true PcomA aneurysms
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2025-01-27 DOI: 10.1016/j.inat.2025.101991
S. Matanov , K. Ninov , K. Minkin , K. Sirakova , G. Vladev , S. Sirakov , A. Sirakov

Background

True posterior communicating artery (PcomA) aneurysms are rare compared to those at the junction of the internal carotid artery (ICA) and PcomA. They account for a small subset of unruptured intracranial aneurysms, yet approximately 20 % present with ophthalmoplegia, significantly impairing quality of life. While direct third nerve compression was considered the primary cause of symptoms, evidence suggests that restricted blood flow can alleviate symptoms. Flow-diverter (FD) stents, while effective for complex aneurysms, are scarcely reported for symptomatic, unruptured true PcomA aneurysms.

Methods

A retrospective study (March 2015–December 2023) included patients with unruptured, saccular true PcomA aneurysms presenting with ophthalmoplegia. Data on demographics, aneurysm characteristics, interventions, clinical outcomes, and occlusion were analyzed.

Results

Endovascular treatment involved loose coiling with an FD in 9 patients (60 %) and FD alone in 6 patients (40 %). All procedures were successful, with no complications. Angiographic follow-up showed total occlusion in 13 out of 15 aneurysms (87 %). At six months, 60 % of patients had complete resolution of ophthalmoparesis, and 40 % showed partial improvement. By 12 months, 73.3 % had complete symptom resolution, and 26.7 % exhibited partial improvement.

Conclusion

FD stents, used alone or with coiling, are promising for treating symptomatic, unruptured true PcomA aneurysms, showing high occlusion rates, safety, and symptom relief. Despite the study’s retrospective design and small cohort, findings highlight the potential of this approach, warranting larger multicenter studies.
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引用次数: 0
Risk factors for moderate disturbance of consciousness in patients with unilateral chronic subdural hematoma
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2025-01-27 DOI: 10.1016/j.inat.2025.101992
Adrian Liebert , Thomas Eibl , Thomas Bertsch , Hans-Herbert Steiner , Karl-Michael Schebesch , Leonard Ritter

Objective

Chronic subdural hematoma (CSDH) patients usually present with mild symptoms; however, a subset of patients presents with disturbance of consciousness (DOC). We analyzed clinical and radiographic factors, which could influence the level of consciousness in CSDH patients before surgery.

Methods

We retrospectively analyzed consecutive unilateral CSDH patients, who were surgically treated in our department from 2018 to 2023. We compared a group of patients with moderate DOC (group 1), defined as a Glasgow Coma Scale (GCS) 9–13, with a control group of awake but symptomatic patients (GCS > 13, group 2). Clinical and radiographic parameters were analyzed in bivariate and multivariate analyses.

Results

41 (12.9 %) patients presented with GCS 9–13 and 276 patients with GCS > 13. In bivariate analysis, radiographic parameters, like greater mean midline shift (p < 0.001), homogenous hypodense type (p = 0.017), additional temporal (p < 0.001) and occipital (p < 0.001) location, “acute-to-chronic” (p = 0.002) and “acute-on-chronic” (p = 0.049) forms were more frequent in group 1. The trabecular hematoma subtype was less common in group 1 (p = 0.002). INR (p = 0.004) and CRP values (p = 0.003) in the preoperative blood sample were significantly higher in group 1. History of ischemic stroke and intake of statins were more common in group 1 (p = 0.033, p = 0.04; resp.). In the multivariate analysis, midline shift (p = 0.033), occipital location (p = 0.005) and history of ischemic stroke (p = 0.046) remained significant.

Conclusion

We could identify factors which contribute to DOC in CSDH patients. Among those are greater midline shift, occipital location and history of ischemic stroke as independent risk factors.
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引用次数: 0
Seizure in a child with cerebellopontine angle tumour
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2025-01-27 DOI: 10.1016/j.inat.2025.101990
Emmanuel Garba Sunday , Eno-Abasi Garba Sunday , Piel Panther Kuol , Ignatius N. Esene , Abdulbasit Opeyemi Muili , Nwafuluaku Emmanuel Chukwudi , Mubarak Jolayemi Mustapha , Yao Christian Hugues Dokponou , Nourou Dine Adeniran Bankole , Alvan-Emeka K. Ukachukwu

Background

Cerebellopontine angle (CPA) tumours in paediatric patients are rare. Cerebellar seizures are infrequent and scarcely discussed. Only one case of paediatric cerebellar seizure due to a CPA tumour is available in the literature.

Methods

We present a 4-year-old girl with features of cerebellar seizure and fever, who was initially managed for febrile convulsion for 8 months at various private facilities. We also conduct a comprehensive search of English-language medical literature on PubMed, Google Scholar, and grey literature using free Google search with the appropriate keywords.

Results

Twenty-three English-language medical literature were published, with 25 cases whose age at presentation ranged from 1 day to 122 months and male: female ratio of 1.18:1. Only one child with cerebellar seizure had CPA tumour, while the rest variously originated from the cerebellum, brainstem or within the fourth ventricle. The age at surgery ranged between one month to 122 months.

Conclusion

Cerebellar seizures should prompt consideration of posterior fossa lesions as a possible cause, provided there are no supratentorial lesions.
{"title":"Seizure in a child with cerebellopontine angle tumour","authors":"Emmanuel Garba Sunday ,&nbsp;Eno-Abasi Garba Sunday ,&nbsp;Piel Panther Kuol ,&nbsp;Ignatius N. Esene ,&nbsp;Abdulbasit Opeyemi Muili ,&nbsp;Nwafuluaku Emmanuel Chukwudi ,&nbsp;Mubarak Jolayemi Mustapha ,&nbsp;Yao Christian Hugues Dokponou ,&nbsp;Nourou Dine Adeniran Bankole ,&nbsp;Alvan-Emeka K. Ukachukwu","doi":"10.1016/j.inat.2025.101990","DOIUrl":"10.1016/j.inat.2025.101990","url":null,"abstract":"<div><h3>Background</h3><div>Cerebellopontine angle (CPA) tumours in paediatric patients are rare. Cerebellar seizures are infrequent and scarcely discussed. Only one case of paediatric cerebellar seizure due to a CPA tumour is available in the literature.</div></div><div><h3>Methods</h3><div>We present a 4-year-old girl with features of cerebellar seizure and fever, who was initially managed for febrile convulsion for 8 months at various private facilities. We also conduct a comprehensive search of English-language medical literature on PubMed, Google Scholar, and grey literature using free Google search with the appropriate keywords.</div></div><div><h3>Results</h3><div>Twenty-three English-language medical literature were published, with 25 cases whose age at presentation ranged from 1 day to 122 months and male: female ratio of 1.18:1. Only one child with cerebellar seizure had CPA tumour, while the rest variously originated from the cerebellum, brainstem or within the fourth ventricle. The age at surgery ranged between one month to 122 months.</div></div><div><h3>Conclusion</h3><div>Cerebellar seizures should prompt consideration of posterior fossa lesions as a possible cause, provided there are no supratentorial lesions.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"39 ","pages":"Article 101990"},"PeriodicalIF":0.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Restorative neurostimulation for chronic low back pain using ReActiv8® in a patient with a large lumbar disc herniation 使用 ReActiv8® 恢复性神经刺激治疗大腰椎间盘突出症患者的慢性腰背痛
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-05-13 DOI: 10.1016/j.inat.2024.101988
Dirar Aldabek , Christian Schürer , Michael Luchtmann

This case report presents the therapeutic effect of restorative neurostimulation (ReActiv8®) on chronic low back pain (CLBP) in a 44-year-old male, where the primary etiology was not lumbar disc herniation (LDH). Despite presenting with LDH at L4-L5, clinical evaluations suggested lumbar microinstability and multifidus muscle dysfunction as the main contributors to his pain, without radicular symptoms. The patient had a 12-year history of CLBP, resistant to conventional treatments like physiotherapy, medications, and epidural injections. Opting for a minimally invasive approach, he underwent implantation of ReActiv8®, focusing on rehabilitating the impaired multifidus muscle. Over a 12-month therapy period, significant improvements were noted in pain levels, functionality, and quality of life, leading to a full return to work. Interestingly, follow-up imaging showed not only a substantial reduction in pain but also an unexpected resolution of the LDH at L4-L5, enhanced lumbar lordosis, and improved disc hydration, despite minor progressing Modic changes. This case underlines the potential of restorative neurostimulation in CLBP management, especially when the pain origin is non-discogenic. It emphasizes the importance of accurate pain source identification in CLBP treatment and suggests further research into the efficacy and applicability of neurostimulation in similar clinical scenarios.

本病例报告介绍了恢复性神经刺激(ReActiv8®)对一名 44 岁男性慢性腰背痛(CLBP)的治疗效果,其主要病因并非腰椎间盘突出症(LDH)。尽管患者表现为 L4-L5 处的腰椎间盘突出症,但临床评估表明,腰椎微稳定性和多裂肌功能障碍是导致其疼痛的主要原因,而没有根性症状。患者有12年的CLBP病史,对理疗、药物和硬膜外注射等传统治疗方法有抵抗力。他选择了一种微创方法,接受了 ReActiv8® 植入手术,重点康复受损的多裂肌。在 12 个月的治疗期间,他的疼痛程度、功能和生活质量都有了明显改善,最终完全恢复了工作。有趣的是,随访影像学结果显示,尽管莫迪氏病变有轻微进展,但患者不仅疼痛明显减轻,而且 L4-L5 处的低密度脂蛋白血症也出乎意料地得到缓解,腰椎前凸得到加强,椎间盘水合作用得到改善。该病例凸显了恢复性神经刺激在慢性椎间盘突出症治疗中的潜力,尤其是当疼痛源不是椎间盘时。它强调了在 CLBP 治疗中准确识别疼痛源的重要性,并建议进一步研究神经刺激在类似临床场景中的疗效和适用性。
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引用次数: 0
Topical dexamethason effectiveness combined with surgical intervention in patients suffering from chronic subdural hematoma 慢性硬膜下血肿患者局部使用地塞米松联合手术治疗的效果
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-05-04 DOI: 10.1016/j.inat.2024.101984
Hosein Safari , Masoud Zeinali , Pooyan Alizadeh , Davood Mahmoudi

Background

A chronic subdural hematoma (CSDH) is one of the most common neurosurgery operations. This study aimed to evaluate the effect of topical corticosteroids combined with surgery in patients with CSDH.

Materials and Methods

The present study is a clinical trial study on patients referred to hospitals associated with Ahvaz University of Medical Sciences with chronic subdural hematoma in 2019. Patients requiring surgical drainage of chronic subdural hematoma who met the inclusion criteria underwent open craniotomy surgery on the side of the hematoma. A drain was placed in the open craniotomy site. On the third day after the operation, before removing the drain, 40 mg of methylprednisolone sodium succinate was injected through the drain into the subdural space, after which the drain was pulled entirely. Patients were evaluated with the Markwalder Grading Scale (MGS) on the third day, third month, and sixth month after surgery for improved or worsened neurological symptoms. Also, in the third and sixth months after surgery, the patients underwent Computerized Tomography Scan imaging and were checked for recurrence.

Results

32 patients with CSDH entered the study, including 28 men and four women, with a mean age of 71.62 ± 9.85 years. Moreover, 87.5 % had a unilateral chronic subdural hematoma (uCSDH), and 12.5 % had a bilateral chronic subdural hematoma (bCSDH). Left and right uCSDHs had the same frequency (43. 8 %). After surgery, 26 patients had no postoperative complications, and six patients experienced pneumocephalus.

Conclusion

Topical dexamethasone injection through the potential CSDH cavity can result in desirable outcomes.

背景慢性硬膜下血肿(CSDH)是最常见的神经外科手术之一。本研究旨在评估局部皮质类固醇联合手术治疗 CSDH 患者的效果。材料与方法本研究是一项临床试验研究,对象是 2019 年转诊至阿瓦士医科大学附属医院的慢性硬膜下血肿患者。符合纳入标准、需要手术引流慢性硬膜下血肿的患者接受了血肿一侧的开颅手术。在开颅手术部位放置引流管。术后第三天,在拔出引流管之前,通过引流管向硬膜下腔注射 40 毫克琥珀酸甲泼尼龙钠,然后完全拔出引流管。术后第三天、第三个月和第六个月,使用马克瓦尔德分级量表(Markwalder Grading Scale,MGS)对患者的神经症状改善或恶化情况进行评估。此外,在术后第三个月和第六个月,患者还接受了计算机断层扫描成像,检查是否有复发。此外,87.5%的患者为单侧慢性硬膜下血肿(uCSDH),12.5%的患者为双侧慢性硬膜下血肿(bCSDH)。左右硬膜下血肿的发生率相同(43.8%)。结论通过潜在的 CSDH 腔局部注射地塞米松可获得理想的效果。
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引用次数: 0
Cerebellopontine angle epidermoid cyst presenting with only trigeminal neuralgia: A retrospective study at the single-center in Vietnam 仅表现为三叉神经痛的小脑角表皮样囊肿:越南单中心回顾性研究
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-04-26 DOI: 10.1016/j.inat.2024.101987
Phuoc Trong Do , Chung Kim Nguyen , Viet-Thang Le

Objective

To assess the influence of clinical and imaging characteristics on the outcome of microsurgery treatment for cerebellopontine angle (CPA) epidermoid cyst (EC) presenting only with trigeminal neuralgia (TN).

Methods

A retrospective observational study describing 42 cases of CPA epidermoid cyst presenting only with TN n CPA for 10 years from 2011 to 2021 with the mean follow-up period was 37 months (range, 6–60 months). This study is the largest research with a long follow-up period reported so far worldwide for ECs with only TN symptom. We analyzed the clinical-radiological records of all the patients who met the rigorous requirements to find the distinct features of these tumors.

Results

The mean age was 40.1 ± 4.7 years. The time from symptom onset to surgery was 8.6 ± 3.9 months. Symptoms of multiple branches of the 5th nerve appeared in 71.4 %, the most common was V2V3 accounting for 42.9 %. Most of the tumors were located limited in the CPA, accounting for 66.7 %. Total resection reached 90.5 %. The effectiveness of pain relief of microsurgery reached 97.6 %, Barrow Neurological Institute (BNI) score I reached 73.8 % and pain relief was 23.8 %. The postoperative neurologic deficit was 14.3 %.

Conclusion

CPA epidermoid cysts presenting with TN as the sole symptom have favorable characteristics for total removing the tumor compared with other tumors in the remaining group. Total removing the tumor with the support of continuous intraoperative electromyography monitoring and decompressing the 5th nerve was ideal; it will not only increase the symptom improvement but also have a low rate of postoperative complications.

方法一项回顾性观察研究,描述了自2011年至2021年10年间42例仅伴有三叉神经痛(TN)的小脑视角(CPA)表皮样囊肿,平均随访时间为37个月(6-60个月)。该研究是迄今为止世界上针对仅有 TN 症状的表皮样囊肿进行的规模最大、随访时间最长的研究。我们分析了所有符合严格要求的患者的临床和放射学记录,以发现这些肿瘤的显著特征。平均年龄为(40.1±4.7)岁,从症状出现到手术时间为(8.6±3.9)个月。71.4%的患者出现第五神经多支症状,其中最常见的是V2V3,占42.9%。大多数肿瘤局限于CPA,占66.7%。总切除率达到 90.5%。显微手术的止痛效果达到97.6%,巴罗神经研究所(Barrow Neurological Institute,BNI)评分I达到73.8%,疼痛缓解率为23.8%。结论CPA表皮样囊肿以TN为唯一症状,与其余组别中的其他肿瘤相比,完全切除肿瘤具有良好的特征。在术中持续肌电图监测和第 5 神经减压的支持下全切肿瘤是最理想的方法,不仅能增加症状改善率,而且术后并发症发生率低。
{"title":"Cerebellopontine angle epidermoid cyst presenting with only trigeminal neuralgia: A retrospective study at the single-center in Vietnam","authors":"Phuoc Trong Do ,&nbsp;Chung Kim Nguyen ,&nbsp;Viet-Thang Le","doi":"10.1016/j.inat.2024.101987","DOIUrl":"https://doi.org/10.1016/j.inat.2024.101987","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the influence of clinical and imaging characteristics on the outcome of microsurgery treatment for cerebellopontine angle (CPA) epidermoid cyst (EC) presenting only with trigeminal neuralgia (TN).</p></div><div><h3>Methods</h3><p>A retrospective observational study describing 42 cases of CPA epidermoid cyst presenting only with TN n CPA for 10 years from 2011 to 2021 with the mean follow-up period was 37 months (range, 6–60 months). This study is the largest research with a long follow-up period reported so far worldwide for ECs with only TN symptom. We analyzed the clinical-radiological records of all the patients who met the rigorous requirements to find the distinct features of these tumors.</p></div><div><h3>Results</h3><p>The mean age was 40.1 ± 4.7 years. The time from symptom onset to surgery was 8.6 ± 3.9 months. Symptoms of multiple branches of the 5th nerve appeared in 71.4 %, the most common was V2V3 accounting for 42.9 %. Most of the tumors were located limited in the CPA, accounting for 66.7 %. Total resection reached 90.5 %. The effectiveness of pain relief of microsurgery reached 97.6 %, Barrow Neurological Institute (BNI) score I reached 73.8 % and pain relief was 23.8 %. The postoperative neurologic deficit was 14.3 %.</p></div><div><h3>Conclusion</h3><p>CPA epidermoid cysts presenting with TN as the sole symptom have favorable characteristics for total removing the tumor compared with other tumors in the remaining group. Total removing the tumor with the support of continuous intraoperative electromyography monitoring and decompressing the 5th nerve was ideal; it will not only increase the symptom improvement but also have a low rate of postoperative complications.</p></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"37 ","pages":"Article 101987"},"PeriodicalIF":0.4,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214751924000331/pdfft?md5=baffea07f25ad52835ea95d7bb1ad5d9&pid=1-s2.0-S2214751924000331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140807257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Teta injury at the craniovertebral junction: A case report 颅椎骨交界处的 Teta 损伤:病例报告
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-04-25 DOI: 10.1016/j.inat.2024.101986
Shuvro Saha, Rafiqul Islam, Rashidul Hasan, Pulak Kumar Biswas

Neck or craniovertebral penetrating injury by in situ teta, used for fishing, is an extremely rare neurosurgical emergency. In this article, we present the management of such a case in Dhaka Medical College Hospital. This case report will emphasize the presentation, investigations, surgical, and other supportive management.

用于捕鱼的原位 Teta 造成颈部或颅椎穿透性损伤是一种极为罕见的神经外科急症。本文介绍了达卡医学院附属医院对此类病例的处理。本病例报告将重点介绍其表现、检查、手术和其他辅助治疗。
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引用次数: 0
Clinical characteristics and management of vertebral artery dissection without definitive imaging features: A single center cohort study 无明确影像学特征的椎动脉夹层的临床特征和处理方法:单中心队列研究
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-04-24 DOI: 10.1016/j.inat.2024.101985
Hironori Fukumoto , Takashi Morishita , Koichiro Takemoto , Hiromasa Kobayashi , Dai Kawano , Yoshinobu Horio , Mitsutoshi Iwaasa , Tooru Inoue , Hiroshi Abe

Background

Management of vertebral artery dissection (VAD), which is difficult to diagnose definitively on imaging, is a clinical concern. The aim of this study was to clarify the clinical characteristics of VAD without definitive imaging features and evaluate our clinical decisions and their consequences.

Methods

We searched our database to identify patients with VAD registered between January 2008 and December 2021. We performed a retrospective chart review to obtain detailed clinical information and compared the clinical characteristics and radiological findings between patients with definitive VAD and those with non-definitive VAD by radiological findings at the initial evaluation.

Results

Of 188 patients (mean age 52.7 ± 12.3 years, 121 male), 127 had definitive VAD. Patients in the definitive group had a younger average age and a high rate of intramural hematoma, while those in the non-definitive group were more likely to have a history of hypertension. Overall, the prognosis was good for the majority (n = 163), and there was no significant difference in the prognosis between two groups. Especially, the prognosis of non-definitive VAD patients without stroke was favorable.

Conclusions

Cases of non-definitive VAD are likely to be complicated by atherosclerotic changes. Therefore, clinicians should carefully evaluate the potential etiologies based on the clinical history and imaging data to provide patients with the optimal treatment options. Identification of IMH was an important factor to make a definitive diagnosis, and the vessel wall imaging is a useful imaging modality for the purpose.

背景椎动脉夹层(VAD)很难通过影像学明确诊断,其管理是临床关注的问题。本研究旨在明确无明确影像学特征的椎动脉夹层的临床特征,并评估我们的临床决策及其后果。方法我们在数据库中搜索了2008年1月至2021年12月期间登记的椎动脉夹层患者。我们进行了回顾性病历审查,以获得详细的临床信息,并根据初次评估时的放射学结果,比较了明确 VAD 患者和无明确 VAD 患者的临床特征和放射学结果。结果 在 188 名患者(平均年龄为 52.7 ± 12.3 岁,121 名男性)中,127 人有明确的 VAD。明确组患者的平均年龄较小,硬膜内血肿发生率较高,而非明确组患者则更可能有高血压病史。总体而言,大多数患者(163 人)的预后良好,两组患者的预后无明显差异。结论非明确性 VAD 病例很可能因动脉粥样硬化病变而变得复杂。因此,临床医生应根据临床病史和影像学资料仔细评估潜在病因,为患者提供最佳治疗方案。识别IMH是明确诊断的一个重要因素,而血管壁成像是一种有用的成像方式。
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引用次数: 0
Type Id versus type IId three-level hybrid surgery for the treatment of noncontiguous cervical spondylosis: A finite element analysis 治疗非连续性颈椎病的Id型与IId型三水平混合手术:有限元分析
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-04-09 DOI: 10.1016/j.inat.2024.101983
Jiang Huang , Xiangyao Sun , Qingming Zhang , Li Cao , Yuqi Liu , Zelong Song , Wei Tang , Siyuan Sun , Juyong Wang

The objective of the research is to simulate different forms of three-level hybrid surgeries, aiming to establish a foundational reference for the selection of suitable treatment strategies for multilevel noncontiguous cervical degenerative disease (CDD). For the development of precise finite element models (FEMs), this study utilized computed tomography (CT) data. Two cross-segment surgical approaches were primarily investigated: C3/4 cervical disc arthroplasty (CDA), C5/6 anterior cervical discectomy and fusion (ACDF), and C6/7 ACDF in the type Id model; C3/4 CDA, C5/6 CDA, and C6/7 ACDF in the type IId model. The follower load technique was employed to apply an initial axial load of 73.6 N at the motion center. Subsequently, a moment of 1.0 Nm was introduced at the center of the C2 vertebra to simulate the overall motion of the model. In contrast to type IId, type Id exhibited lower average intervertebral disc pressure in C4/5 across various motions. The average intervertebral disc pressure in C2/3 was higher in type Id compared to type IId in flexion and axial rotation, whereas the reverse was observed in lateral bending. Type IId exhibited notably lower facet joint contact stresses during extension in C2/3 and C4/5 when compared to type Id. Type Id has a better protective effect on IS, and can significantly reduce the average pressure of the intervertebral disc in IS compared with type IId. Type IId has a significant protective effect on the post-column structure of non-fused segments.

这项研究的目的是模拟不同形式的三水平混合手术,旨在为多水平非连续性颈椎退行性疾病(CDD)选择合适的治疗策略提供基础参考。为了建立精确的有限元模型(FEM),本研究利用了计算机断层扫描(CT)数据。主要研究了两种跨节手术方法:C3/4颈椎间盘关节成形术(CDA)、C5/6颈椎前路椎间盘切除融合术(ACDF)和C6/7 ACDF(Id型模型);C3/4 CDA、C5/6 CDA和C6/7 ACDF(IId型模型)。采用随动载荷技术在运动中心施加 73.6 N 的初始轴向载荷。随后,在 C2 椎体中心引入 1.0 牛米的力矩,以模拟模型的整体运动。与 IId 型相比,Id 型在各种运动中的 C4/5 椎间盘平均压力较低。与 IId 型相比,Id 型在屈曲和轴向旋转时 C2/3 的平均椎间盘压力较高,而在侧弯时则相反。与Id型相比,IId型在C2/3和C4/5伸展时的面关节接触应力明显较低。与 IId 型相比,Id 型对 IS 有更好的保护作用,能显著降低 IS 中椎间盘的平均压力。IId 型对未融合节段的柱后结构具有明显的保护作用。
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引用次数: 0
A large extruded L5-S1 disc causing progressive compression and neurological deficits(CES) with slow recovery after surgery L5-S1 椎间盘突出导致进行性压迫和神经功能缺损(CES),术后恢复缓慢
IF 0.4 Q4 CLINICAL NEUROLOGY Pub Date : 2024-04-08 DOI: 10.1016/j.inat.2024.101982
Mehdi Mahmoodkhani, Majid Rezvani, Mehdi Shafiei, Amir Mahabadi, Navid Askariardejani

A 40-year-old male presented with progressive paresthesia and weakness of the lower limbs and sphincter dysfunction. He had a history of low back pain and disk herniation from five years ago. Magnetic resonance imaging (MRI) revealed a very large mass-like lesion at L5-S1 segments, and computed tomography (CT) showed destruction of L5 lamina. While the main diagnosis was a large extruded disc, the possibility of extradural masses such as chordoma was also considered. The patient was immediately started on corticosteroid therapy and underwent laminectomy and discectomy surgery to remove the large free fragment compressing the neural elements. The patient reported feeling improvement in his feet and perineum one day after surgery, but follow-up examinations one and three months after surgery described incomplete recovery in sphincter function. This case highlights the importance of considering other possible diagnoses based on physical examination and imaging findings, even when the initial diagnosis seems clear, and emphasizes the need for timely intervention in cases of spinal cord compression to prevent permanent damage to the neural elements.

一名 40 岁的男性因下肢进行性麻痹和无力以及括约肌功能障碍前来就诊。他在五年前曾有腰痛和椎间盘突出的病史。磁共振成像(MRI)显示 L5-S1 节段有一个非常大的肿块样病变,计算机断层扫描(CT)显示 L5 椎板受到破坏。虽然主要诊断是巨大的椎间盘突出,但也考虑了硬膜外肿块(如脊索瘤)的可能性。患者立即开始接受皮质类固醇治疗,并接受了椎板切除术和椎间盘切除术,切除了压迫神经元的大块游离碎片。术后一天,患者报告其足部和会阴部感觉有所改善,但术后一个月和三个月的随访检查显示其括约肌功能未完全恢复。本病例强调了根据体格检查和影像学检查结果考虑其他可能诊断的重要性,即使初步诊断似乎很明确,并强调了在脊髓受压病例中及时干预的必要性,以防止对神经元造成永久性损伤。
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引用次数: 0
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Interdisciplinary Neurosurgery: Advanced Techniques and Case Management
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