Editorial | Volume 4 | Number 1| e5 Copyright 2018 by Watanabe S. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc C kidney disease (CKD) is pervasive into aging society, affecting permanent implications on patients’ life. Approximately 10% of the global population has CKD, and millions die each year. The prevalence of CKD was high in Latin America, Europe, East Asia and the Middle East, where approximately 12% of the population has CKD.1 Diabetic kidney disease (DKD) or diabetic nephropathy (DN) is a part of CKD when the patients have diabetes.2 Both CKD and DKD may progressively fall from a normal estimated glomerular filtration rate (eGFR >90 ml/min/1.73 m2) to less than 15, at which point the patient becomes end-stage kidney disease (ESKD). The status of DKD could be estimated by measuring the amount of urinary protein and the serum creatinine, which can be used to calculate the eGFR.
这是一篇基于知识共享署名4.0国际许可(CC by 4.0)的开放获取文章，允许以任何媒介或格式复制、再分发、再混合、转换和复制，即使是商业复制，前提是正确引用原始作品。慢性肾脏病(CKD)在老龄化社会中普遍存在，对患者的生活产生永久性影响。全球大约10%的人口患有慢性肾病，每年有数百万人死亡。拉丁美洲、欧洲、东亚和中东地区CKD患病率较高，约12%的人口患有CKD.1糖尿病肾病(DKD)或糖尿病肾病(DN)是CKD的一部分，当患者患有糖尿病CKD和DKD都可能从正常的肾小球滤过率(eGFR >90 ml/min/1.73 m2)逐渐下降到小于15，此时患者成为终末期肾病(ESKD)。通过测定尿蛋白和血清肌酐的含量来判断DKD的状态，并以此计算eGFR。
{"title":"Low Protein Brown Rice for Preventing Progression of CKD and DKD to End Stage Renal Failure","authors":"Shaw Watanabe","doi":"10.17140/droj-4-e012","DOIUrl":"https://doi.org/10.17140/droj-4-e012","url":null,"abstract":"Editorial | Volume 4 | Number 1| e5 Copyright 2018 by Watanabe S. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc C kidney disease (CKD) is pervasive into aging society, affecting permanent implications on patients’ life. Approximately 10% of the global population has CKD, and millions die each year. The prevalence of CKD was high in Latin America, Europe, East Asia and the Middle East, where approximately 12% of the population has CKD.1 Diabetic kidney disease (DKD) or diabetic nephropathy (DN) is a part of CKD when the patients have diabetes.2 Both CKD and DKD may progressively fall from a normal estimated glomerular filtration rate (eGFR >90 ml/min/1.73 m2) to less than 15, at which point the patient becomes end-stage kidney disease (ESKD). The status of DKD could be estimated by measuring the amount of urinary protein and the serum creatinine, which can be used to calculate the eGFR.","PeriodicalId":385648,"journal":{"name":"Diabetes Research - Open Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115612273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subhashini Chandrasekaran, B. Szirth, Kim Duong, J. Stroud, H. Cope, Peter Khouri, C. Khouri, K. Soules, California Usa Optovue
Clinical Study | Volume 4 | Number 1| 12 Copyright 2018 by Szirth BC, et al. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc ABSTRACT Background: Type 1 Diabetes Mellitus is among the most common conditions worldwide, affecting nearly 95 million children worldwide. One of the detrimental effects of this condition can be vision loss. Comprehensive annual ocular screenings can have an important role in early detection and management of vision-threatening complications. Over 2,200 family members and children with diabetes type 1 (www.childrenwithdiabetes.com) from Australia, Asia, Canada, Europe, Latin America and the United States of America attended an annual meeting where participants wishing to undergo a full ocular wellness screening had to pre-register for this weeklong activity.
临床研究|第4卷|第1期| 12版权所有:Szirth BC等。这是一篇在知识共享署名4.0国际许可(CC BY 4.0)下发布的开放获取文章，允许在任何媒介或格式下复制、再分发、再混合、转换和复制，甚至是商业复制，只要正确引用原始作品。背景:1型糖尿病是世界上最常见的疾病之一，影响着全球近9500万儿童。这种情况的一个有害影响可能是视力丧失。全面的年度眼部筛查对早期发现和处理视力威胁并发症具有重要作用。来自澳大利亚、亚洲、加拿大、欧洲、拉丁美洲和美利坚合众国的2,200多名患有1型糖尿病的家庭成员和儿童(www.childrenwithdiabetes.com)参加了一年一度的会议，希望接受全面眼部健康筛查的参与者必须预先登记参加为期一周的活动。
{"title":"Ocular Health Screening in a Type 1 Diabetes Mellitus Population","authors":"Subhashini Chandrasekaran, B. Szirth, Kim Duong, J. Stroud, H. Cope, Peter Khouri, C. Khouri, K. Soules, California Usa Optovue","doi":"10.17140/DROJ-4-138","DOIUrl":"https://doi.org/10.17140/DROJ-4-138","url":null,"abstract":"Clinical Study | Volume 4 | Number 1| 12 Copyright 2018 by Szirth BC, et al. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc ABSTRACT Background: Type 1 Diabetes Mellitus is among the most common conditions worldwide, affecting nearly 95 million children worldwide. One of the detrimental effects of this condition can be vision loss. Comprehensive annual ocular screenings can have an important role in early detection and management of vision-threatening complications. Over 2,200 family members and children with diabetes type 1 (www.childrenwithdiabetes.com) from Australia, Asia, Canada, Europe, Latin America and the United States of America attended an annual meeting where participants wishing to undergo a full ocular wellness screening had to pre-register for this weeklong activity.","PeriodicalId":385648,"journal":{"name":"Diabetes Research - Open Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134106933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Opinion | Volume 4 | Number 1| 9 Copyright 2018 by Bando H. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc For the patients with diabetes, basal daily lifestyle would be considered in the light of meal, exercise, rest, alcohol intake, smoking and oral health. These six factors are from the concept as a basic direction of “Health Japan 21” for comprehensive implementation of national health promotion.1 Satisfactory control of lifestyle can lead to protection and treatment of diabetes and successful anti-aging. From this implication, to check up physical and mental condition would be important and helpful in clinical practice.
观点| Volume 4 | Number 1| 9版权所有2018 by Bando H.这是一篇根据知识共享署名4.0国际许可(CC by 4.0)发布的开放获取文章，允许以任何媒介或格式复制、再分发、再混合、转换和复制，即使是商业复制，前提是正确引用原始作品。对于糖尿病患者，基本的日常生活方式包括饮食、运动、休息、饮酒、吸烟和口腔健康。这六个因素是从理念上作为“健康日本21”全面实施国民健康促进的基本方向良好的生活方式控制可以预防和治疗糖尿病，成功地延缓衰老。从这个意义上说，检查身体和精神状况在临床实践中是重要的和有益的。
{"title":"More Significant Life for Diabetic Patients in the Perspectives of Anti-Aging","authors":"H. Bando","doi":"10.17140/DROJ-4-137","DOIUrl":"https://doi.org/10.17140/DROJ-4-137","url":null,"abstract":"Opinion | Volume 4 | Number 1| 9 Copyright 2018 by Bando H. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc For the patients with diabetes, basal daily lifestyle would be considered in the light of meal, exercise, rest, alcohol intake, smoking and oral health. These six factors are from the concept as a basic direction of “Health Japan 21” for comprehensive implementation of national health promotion.1 Satisfactory control of lifestyle can lead to protection and treatment of diabetes and successful anti-aging. From this implication, to check up physical and mental condition would be important and helpful in clinical practice.","PeriodicalId":385648,"journal":{"name":"Diabetes Research - Open Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121789344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Abe, M. Nakanishi, Osami Watanabe, H. Kawano, H. Bando
Acute increase of type 2 diabetes mellitus (T2DM) is a serious medical problem. Recently, an agent known as Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) was developed for T2DM which has remarkable efficacy and safety profile. In this article, we reported 2 T2DM cases with dulaglutide treatment, showing interesting clinical course. Case 1 is an 88-year-old man with hypertension, arteriosclerosis and mild cognitive impairment (MCI) without difficulties of Quality of Life (QOL)/Activities in Daily living (ADL) in daily life. He has been rather stable on liraglutide with HbA1c 7.2%. After switching from liraglutide to dulaglutide, HbA1c decreased to 6.7% in 2 months, but later increased to 11.3% in 3 months. C-peptide index (CPI) decreased from 2.5 to 0.8. Case 2 is an 83-year-old man and was treated by degludec with CPI 1.35. After switching to dulaglutide, HbA1c decreased to 7.6% in 2 months, but later increased to 10.3% in 2 months. These two cases revealed similar clinical course. Some possibilities might be speculated, including antibody production, differences of GLP-1 RAs from man-origin or lizard-origin, changes in body weight, a possible complication of renal, hepatic inflammatory influences and the subacute decreased ability of insulin secretion in the β cells. The current report would be useful for treatment of GLP-1 RAs in the future.
{"title":"Attenuated Efficacy of Dulaglutide in Elder Type 2 Diabetes Mellitus (T2DM) Cases","authors":"T. Abe, M. Nakanishi, Osami Watanabe, H. Kawano, H. Bando","doi":"10.17140/DROJ-4-136","DOIUrl":"https://doi.org/10.17140/DROJ-4-136","url":null,"abstract":"Acute increase of type 2 diabetes mellitus (T2DM) is a serious medical problem. Recently, an agent known as Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) was developed for T2DM which has remarkable efficacy and safety profile. In this article, we reported 2 T2DM cases with dulaglutide treatment, showing interesting clinical course. Case 1 is an 88-year-old man with hypertension, arteriosclerosis and mild cognitive impairment (MCI) without difficulties of Quality of Life (QOL)/Activities in Daily living (ADL) in daily life. He has been rather stable on liraglutide with HbA1c 7.2%. After switching from liraglutide to dulaglutide, HbA1c decreased to 6.7% in 2 months, but later increased to 11.3% in 3 months. C-peptide index (CPI) decreased from 2.5 to 0.8. Case 2 is an 83-year-old man and was treated by degludec with CPI 1.35. After switching to dulaglutide, HbA1c decreased to 7.6% in 2 months, but later increased to 10.3% in 2 months. These two cases revealed similar clinical course. Some possibilities might be speculated, including antibody production, differences of GLP-1 RAs from man-origin or lizard-origin, changes in body weight, a possible complication of renal, hepatic inflammatory influences and the subacute decreased ability of insulin secretion in the β cells. The current report would be useful for treatment of GLP-1 RAs in the future.","PeriodicalId":385648,"journal":{"name":"Diabetes Research - Open Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131378076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：