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Efficacy of Dialectical Behavior Therapy in the Treatment of Borderline Personality Disorder: A Systematic Review of Randomized Controlled Trials 辩证行为疗法治疗边缘型人格障碍的疗效:随机对照试验的系统回顾
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14347
Milton Hernandez-Bustamante, J. Cjuno, Ronald M. Hernández, Jacqueline C. Ponce-Meza
Objective: Borderline personality disorder (BPD) is a serious public health problem. Dialectical Behavior Therapy (DBT) is a program that has provided encouraging results for its treatment. However, scientific evidence about its efficacy is scarce. Therefore, we aimed to describe the scientific production on the components of the DBT program and its therapeutic efficacy in the treatment of people with BPD. Method: A systematic review with relevant keywords was conducted based on studies available in Scopus, Web of Science, and PubMed until June 2023, including studies in English, research on therapeutic intervention, studies with a randomized controlled trial (RCT) design that included people with the diagnosis of BPD. Results: We found 18 RCTs, most of which supported the effectiveness of DBT for BPD. There were a total of 1,755 participants in these studies, most of whom were women. These studies looked for treating self-injurious behaviors, suicidal thoughts or ideations, number of visits to emergency services, and frequency of hospital admissions. Most studies revealed that both short-term DBT and standard DBT improved suicidality in BPD patients with small or moderate effect sizes, lasting up to 24 months after the treatment period. Furthermore, these studies showed that DBT can significantly improve general psychopathology and depressive symptoms in patients with BPD. Improvement of compliance, impulsivity, mood instability, as well as reduction in hospitalization rate are other findings observed in the trials following DBT. Conclusion: Although DBT shows efficacy in the treatment of BPD, heterogeneity in the methodologies employed is highlighted. Therefore, it is necessary to design studies from a homogeneous theoretical and methodological framework.
目的:边缘型人格障碍(BPD)是一个严重的公共健康问题。辩证行为疗法(DBT)是一种在治疗上取得了令人鼓舞的效果的方案。然而,有关其疗效的科学证据却很少。因此,我们旨在描述有关 DBT 方案的组成部分及其对治疗 BPD 患者的疗效的科学成果。方法:根据 Scopus、Web of Science 和 PubMed 上截至 2023 年 6 月的相关研究,使用相关关键词进行了系统性综述,包括英语研究、治疗干预研究、采用随机对照试验(RCT)设计的研究,并纳入了被诊断为 BPD 的患者。结果:我们发现了 18 项随机对照试验,其中大部分支持 DBT 治疗 BPD 的有效性。这些研究共有 1,755 名参与者,其中大部分是女性。这些研究调查了治疗自伤行为、自杀想法或意念、急诊就诊次数以及入院频率。大多数研究显示,短期 DBT 和标准 DBT 都能改善 BPD 患者的自杀倾向,且效果或小或中等,治疗期后可持续 24 个月。此外,这些研究还表明,DBT 可以显著改善 BPD 患者的一般精神病理学和抑郁症状。DBT 治疗后,患者的依从性、冲动性、情绪不稳定性得到改善,住院率也有所下降。结论:尽管 DBT 在治疗 BPD 方面显示出了疗效,但所采用方法的异质性也很突出。因此,有必要从统一的理论和方法框架出发设计研究。
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引用次数: 0
Neural Correlates of Social Decision-Making 社会决策的神经相关性
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14350
Natalya Labutina, Sergey Polyakov, Liudmila Nemtyreva, Alina Shuldishova, Olga Gizatullina
Objective: Recent studies have utilized innovative techniques to investigate the neural mechanisms underlying social and individual decision-making, aiming to understand how individuals respond to the world. Method: In this review, we summarized current scientific evidence concerning the neural underpinnings of social decision-making and their impact on social behavior. Results: Critical brain regions involved in social cognition and decision-making are integral to the process of social decision-making. Notably, the medial prefrontal cortex (mPFC) and temporoparietal junction (TPJ) contribute to the comprehension of others' mental states. Similarly, the posterior superior temporal sulcus (pSTS) shows heightened activity when individuals observe faces and movements. On the lateral surface of the brain, the inferior frontal gyrus (IFG) and inferior parietal sulcus (IPS) play a role in social cognition. Furthermore, the medial surface of the brain, including the amygdala, anterior cingulate cortex (ACC), and anterior insula (AI), also participates in social cognition processes. Regarding decision-making, functional magnetic resonance imaging (fMRI) studies have illuminated the involvement of a network of brain regions, encompassing the ventromedial prefrontal cortex (vmPFC), ventral striatum (VS), and nucleus accumbens (NAcc). Conclusion: Dysfunction in specific subregions of the prefrontal cortex (PFC) has been linked to various psychiatric conditions. These subregions play pivotal roles in cognitive, emotional, and social processing, and their impairment can contribute to the development and manifestation of psychiatric symptoms. A comprehensive understanding of the unique contributions of these PFC subregions to psychiatric disorders has the potential to inform the development of targeted interventions and treatments for affected individuals.  
研究目的最近的研究利用创新技术研究了社会和个人决策的神经机制,旨在了解个人如何对世界做出反应。研究方法在这篇综述中,我们总结了当前有关社会决策的神经基础及其对社会行为影响的科学证据。研究结果参与社会认知和决策的关键脑区与社会决策过程密不可分。值得注意的是,内侧前额叶皮层(mPFC)和颞顶交界处(TPJ)有助于理解他人的心理状态。同样,后颞上沟(pSTS)在观察人脸和动作时也会显示出更强的活动性。在大脑外侧表面,额叶下回(IFG)和顶叶下沟(IPS)在社会认知中发挥作用。此外,大脑内侧表面,包括杏仁核、前扣带回皮层(ACC)和前岛叶(AI),也参与社会认知过程。关于决策,功能性磁共振成像(fMRI)研究表明,包括腹外侧前额叶皮层(vmPFC)、腹侧纹状体(VS)和伏隔核(NAcc)在内的大脑区域网络参与了决策过程。结论前额叶皮质(PFC)特定亚区的功能障碍与各种精神疾病有关。这些亚区在认知、情感和社会处理过程中起着关键作用,它们的功能受损会导致精神症状的发展和表现。全面了解这些前脑皮质亚区对精神疾病的独特贡献,有可能为开发针对受影响个体的干预和治疗方法提供信息。
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引用次数: 0
The Concept of Prosociality in Later Life and Its Dimensions: A Scoping Review 晚年亲社会性的概念及其维度:范围审查
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14348
Tahereh Ramezani, N. Zanjari, Hassan Rafiey, Ahmad Delbari
Objective: The aim of this study was to clarify various aspects and dimensions of the prosociality concept in later life as an important concept that gains significance in people as they age. This concept has been expressed through a variety of dimensions in different studies. Method: This is a scoping review of the relevant literature on the concept of prosociality and its dimensions in later life, including quantitative and qualitative studies. The required data were collected from Web of Science, Scopus, PubMed, ProQuest, and Google Scholar databases between the years 1987 and 2022. Results: First, 877 articles were identified, and after the screening phase, 57 eligible studies were reviewed. Two main categories, prosocial dispositions and prosocial behaviors, and seven subcategories were extracted. The subcategories of prosocial dispositions include empathy, prosocial norms, innate tendencies, and generative desires. Prosocial behaviors subcategories include informal spontaneous helping, formal planned helping, and pro-environmental behaviors. Conclusion: The various aspects and dimensions of the prosociality concept in later life identified in this study can be used as a basis for assessing and planning the promotion of prosociality among older adults.
研究目的本研究旨在阐明晚年亲社会性概念的各个方面和维度,因为它是一个重要的概念,随着人们年龄的增长而变得越来越重要。在不同的研究中,这一概念有不同的表现形式。研究方法这是对晚年生活中亲社会性概念及其维度的相关文献,包括定量和定性研究进行的一次范围性综述。所需数据来自 1987 年至 2022 年期间的 Web of Science、Scopus、PubMed、ProQuest 和 Google Scholar 数据库。研究结果首先确定了 877 篇文章,经过筛选阶段,对 57 项符合条件的研究进行了审查。提取了两个主要类别,即亲社会倾向和亲社会行为,以及七个子类别。亲社会倾向的子类别包括同理心、亲社会规范、先天倾向和生成欲望。亲社会行为子类别包括非正式的自发帮助、正式的有计划帮助和亲环境行为。结论本研究确定的晚年亲社会性概念的各个方面和维度可作为评估和规划促进老年人亲社会性的基础。
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引用次数: 0
Psychometric Evaluation of a Persian Version of Beliefs about Emotions Scale in Community and Clinical Samples 在社区和临床样本中对波斯语版 "情绪信念量表 "进行心理计量学评估
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14343
Ala Ghapanchi, Imaneh Abasi, Katharine A. Rimes, Maryam Bitarafan, Hamid Zarabi, Fatemeh Sara Derakhshan, M. Derakhshan, Sepideh Ghanadanzadeh, Helena Whitley, Alireza Shamsi
Objective: This research is primarily conducted to determine the psychometric properties of the Beliefs about Emotions Scale (BES) in community and clinical samples. The BES is a scale measure used for evaluating individuals’ beliefs in terms of how acceptable it is for them to experience and express their emotions. Method: This study was conducted on two separate samples. In the first part, 300 individuals were selected from a general sample in Tehran using the quota sampling method. For the second part of the study, we used purposive sampling to gather data from 119 patients suffering from Major Depressive Disorder (MDD) and 121 patients from Somatic Symptoms Disorder (SSD), whose disorders were diagnosed based on the DSM-5 diagnostic criteria. The BES structural validity was examined through Confirmatory Factor Analysis (CFA). Additionally, test-retest composite and internal consistency indices were explored to investigate the reliability of the BES score. Finally, the associations of the BES score with the Hospital Anxiety and Depression Scale (HADS), Young Schema Questionnaire (YSQ), Multidimensional Perfectionism Scale (MPS), Difficulties in Emotion Regulation Scale (DERS), and Emotion Regulation Questionnaire (ERQ) scores were highlighted to investigate the discriminant and convergent validity of the BES score. Results: According to CFAs, the one-factor model for the BES demonstrated a good fit with the data collected from both the clinical and community samples. The internal consistency (Cronbach's alpha) was satisfactory in the community sample (α = 0.84) and the clinical samples of SSD (α = 0.86) and MDD (α = 0.83). The community sample demonstrated high overall test-retest reliability (ICC = 0.93, P < 0.001; 95% CI: 0.89 - 0.95). In terms of convergent validity, the findings confirmed that in the MMD sample, there was a significant relationship between the BES and almost all measures (including Depression (r = 0.39, P < 0.01), Anxiety (r = 0.21, P < 0.05), Self-Sacrifice (r = 0.27, P < 0.01), MPS-total score (r = 0.22, P < 0.05), DERS total score (r = 0.50, P < 0.01), and Suppression (r = 0.38, P < 0.01). However, in the SSD group, this finding was not found. Conclusion: The results demonstrated that the Persian BES is a reliable and valid scale of maladaptive beliefs about emotions which could be implemented for both clinical and research aims.  
研究目的本研究的主要目的是确定情绪信念量表(BES)在社区和临床样本中的心理测量特性。BES 是一种量表,用于评估个人对体验和表达情绪的可接受性的信念。研究方法:本研究在两个不同的样本中进行。第一部分,采用配额抽样法从德黑兰的普通样本中抽取了 300 人。在研究的第二部分,我们采用了目的性抽样法,从 119 名重度抑郁障碍(MDD)患者和 121 名躯体症状障碍(SSD)患者中收集数据,这些患者的疾病是根据 DSM-5 诊断标准诊断出来的。通过确证因子分析(CFA)检验了 BES 的结构有效性。此外,还探讨了测试-再测试复合指数和内部一致性指数,以研究 BES 分数的可靠性。最后,研究人员强调了 BES 分数与医院焦虑抑郁量表(HADS)、青年模式问卷(YSQ)、多维完美主义量表(MPS)、情绪调节困难量表(DERS)和情绪调节问卷(ERQ)分数之间的关联,以探讨 BES 分数的判别效度和收敛效度。结果根据 CFAs,BES 的单因素模型与从临床和社区样本中收集的数据均表现出良好的拟合性。社区样本(α = 0.84)以及 SSD(α = 0.86)和 MDD(α = 0.83)临床样本的内部一致性(Cronbach's alpha)令人满意。社区样本显示出较高的总体测试-重复测试可靠性(ICC = 0.93,P < 0.001;95% CI:0.89 - 0.95)。在收敛效度方面,研究结果证实,在 MMD 样本中,BES 与几乎所有测量指标(包括抑郁(r = 0.39,P < 0.01)、焦虑(r = 0.21,P < 0.05)、自我牺牲(r = 0.27,P < 0.01)、MPS 总分(r = 0.22,P < 0.05)、DERS 总分(r = 0.50,P < 0.01)和压抑(r = 0.38,P < 0.01)。然而,在 SSD 组中却没有发现这一结果。结论研究结果表明,波斯语 BES 是一种可靠、有效的情绪适应不良信念量表,可用于临床和研究目的。
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引用次数: 0
The Relationship between Gene SLC6A3 Variable Number of Tandem Repeat (VNTR) and Attention-Deficit / Hyperactivity Disorder 基因 SLC6A3 可变串联重复数 (VNTR) 与注意力缺陷/多动症的关系
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14345
Abbas Seymari, Ashkan Naseh, Sajjad Rezaei, Zivar Salehi, Maryam Kousha
Objective: This research investigates the alleles of Variable Number of Tandem Repeats (VNTR) intron 8 of the gene SLC6A3 with attention-deficit / hyperactivity disorder (ADHD) in children and adolescents. Method: The study’s target population consisted of children and adolescents referred to the specialized clinic, as well as students attending school in Rasht city during 2021-2022. A sample of 95 children between the ages of 6 and 10 with ADHD was selected as the ADHD group, and 95 healthy children were selected as the control group using purposive sampling. The subjects completed the Child Symptom Inventory-4 (CSI-4) checklist after a clinical interview, and demographic information was collected. Genetic sampling was carried out through hair follicles. The sequence of interest was proliferated using the Polymerase Chain Reaction technique )PCR(; afterward, the samples were used for genotype identification on polyacrylamide gel electrophoresis. Results: The chi-square test results indicated that the 5R / 5R genotype (P = 0.026, χ2 = 7.26) and the 5R allele (P = 0.002, χ2 = 9.35) had a higher frequency compared to the control group. Additionally, the odds ratio test indicated that, compared to other genotypes and alleles, the 5R / 5R genotype (OR = 2.75, 95% CI = 1.29-5.82, P = 0.01) and the 5R allele (OR = 2.02, 95% CI = 1.28-3.19, P = 0.002) increase the odds of developing ADHD by 2.7 and 2 times higher, respectively. Conclusion: The present study successfully showed the association between intron 8 gene polymorphism, which is responsible for encoding the dopamine transporter as well as ADHD in children and adolescents in Iran.
研究目的本研究调查 SLC6A3 基因内含子 8 可变串联重复数(VNTR)等位基因与儿童和青少年注意力缺陷/多动症(ADHD)的关系。研究方法研究对象包括 2021-2022 年期间转诊到专科诊所的儿童和青少年,以及拉什特市的在校学生。采用目的取样法,抽取 95 名 6 至 10 岁患有多动症的儿童作为多动症组,同时抽取 95 名健康儿童作为对照组。受试者在接受临床访谈后填写儿童症状量表-4(CSI-4)检查表,并收集人口统计学信息。基因采样通过毛囊进行。使用聚合酶链式反应技术(PCR)对感兴趣的序列进行增殖,然后用聚丙烯酰胺凝胶电泳对样本进行基因型鉴定。结果卡方检验结果显示,与对照组相比,5R / 5R 基因型(P = 0.026,χ2 = 7.26)和 5R 等位基因(P = 0.002,χ2 = 9.35)的频率较高。此外,几率比测试表明,与其他基因型和等位基因相比,5R / 5R 基因型(OR = 2.75,95% CI = 1.29-5.82,P = 0.01)和 5R 等位基因(OR = 2.02,95% CI = 1.28-3.19,P = 0.002)患多动症的几率分别增加了 2.7 倍和 2 倍。结论本研究成功揭示了编码多巴胺转运体的内含子 8 基因多态性与伊朗儿童和青少年多动症之间的关联。
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引用次数: 0
Mental Health Services Integration in Primary Health Care in Iran: A Policy Analysis 伊朗将心理健康服务纳入初级医疗保健:政策分析
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14339
A. Dorosti, M. Karamouz, V. Rahimi, Solmaz Azimzadeh, H. Gharaee, S. Azami-aghdash, Mostafa Farahbakhsh
Objective: The National Mental Health Services (N-MHSs) in Iran was integrated with Primary Health Care (PHC) in 1988. This study aimeds to analyze the policy of integrating N-MHSs in PHC, focusing on the analysis of the current situation, pathology, and the existing challenge. Method: This qualitative research was conducted in 2020 using a case study approach. This study used the policy triangle model to analyze the policy. The required data were collected via interviews, literature review, and document analysis. The interviews were conducted with 23 experts, stakeholders across the country who were selected through purposive sampling, and the data were analyzed using the content-analysis method. Results: The main goals of this policy were to raise mental health literacy among the people and eliminate its stigma in the society, while implementing the referral system for N-MHSs. Twenty weaknesses were extracted in eight areas, including negative views of mental health, weaknesses in human resource training, compensation for the service of psychologists, unfavorable working conditions of the workforce, inappropriate service delivery facilities, lack of meaningful communication between different levels of service delivery, poor inter-sectorial communication, and the challenging nature of mental health care. De-stigmatizing psychological disorders in the society and identifying hidden patients are some of the most significant achievements of this policy. Conclusion: Despite the successful implementation and significant achievements in integrating N-MHSs in PHC, the results of the present study indicate that there are many challenges in this field that require serious planning and attention from relevant authorities.
目的伊朗的国家心理健康服务(N-MHSs)于 1988 年与初级保健(PHC)相结合。本研究旨在分析将国家心理健康服务纳入初级保健的政策,重点是分析现状、病理和现有挑战。研究方法:这项定性研究于 2020 年进行,采用个案研究的方法。本研究采用政策三角模型对政策进行分析。通过访谈、文献综述和文件分析收集所需数据。通过有目的的抽样,在全国范围内选择了 23 位专家和利益相关者进行了访谈,并使用内容分析法对数据进行了分析。结果:该政策的主要目标是提高人们的心理健康素养,消除社会对心理健康的偏见,同时实施国家心理健康中心的转诊制度。从八个方面提取了 20 个薄弱环节,包括对心理健康的负面看法、人力资源培训的薄弱环节、心理学家的服务报酬、工作队伍的不利工作条件、不适当的服务设施、不同服务层次之间缺乏有意义的沟通、部门间沟通不畅以及心理保健的挑战性。消除社会对心理疾病的污名化和识别隐性病人是这项政策取得的一些最重要的成就。结论:尽管在将非传染性疾病纳入初级保健方面取得了成功实施和重大成就,但本研究的结果表明,在这一领域还存在许多挑战,需要有关当局认真规划和关注。
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引用次数: 0
Aging Enjoyment: A Grounded Theory Study 老有所乐:基础理论研究
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14338
Zahra Sari-ol Qadam, Marzieh Alivandi Vafa, Touraj Hashemi, Amir Panah Ali
Objective: The aim of this study was to investigate the factors contributing to enjoyment in old age. Method: To this end, this research used a qualitative exploratory research design known as grounded-theory research. Seventeen elderly participants (aged 65-85 years), comprising 11 men and 6 women, were selected using purposive sampling. A semi-structured interview was used as the data collection instrument. The method proposed by Corbin and Strauss was employed to design the interview questions. In this study, data analysis was interpretive using phenomenological analysis, which was done through open, axial, and selective coding. Results: The results indicated that the new emergent construct – ageing enjoyment – consisted of five categories and 19 subcategories. These categories include present moment awareness, liberating past, psychosocial safety, ultimate purpose for being, and self-peace. Subcategories include: Vitality, Family solidarity and intimacy, Occupational Adequacy, Economic wisdom, Social Acceptability, Healthy society, Talent flourish, productive experiences, Physical well-being, Willingness to develop, Mindfulness, satisfaction, Moralization, Adaptability, Benevolence, Acceptance, Desire to live, Meaningfulness, Religiosity. Conclusion: These categories suggest that present moment awareness, liberating past, as well as having psychosocial safety help the elderly experience ageing enjoyment. Hence, they are likely to reach self-peace through an ultimate purpose for being as they deal with challenging life issues. Practical implications of the findings are further discussed
研究目的本研究的目的是调查老年生活乐趣的促成因素。研究方法为此,本研究采用了被称为基础理论研究的定性探索性研究设计。研究采用目的性抽样法,选取了 17 名老年参与者(65-85 岁),其中男性 11 人,女性 6 人。研究采用半结构式访谈作为数据收集工具。在设计访谈问题时,采用了 Corbin 和 Strauss 提出的方法。本研究采用现象学分析法对数据进行解释性分析,通过开放式、轴向和选择性编码完成。研究结果结果表明,新出现的建构--老有所乐--包括五个类别和 19 个子类别。这些类别包括当下意识、解放过去、社会心理安全、存在的终极目的和自我安宁。子类别包括活力、家庭团结和亲密关系、职业适足性、经济智慧、社会可接受性、健康社会、人才兴旺、富有成效的经验、身体健康、发展意愿、心智、满意度、道德化、适应性、仁慈、接受、生活愿望、意义、宗教性。结论这些分类表明,当下意识、解放过去以及社会心理安全有助于老年人体验到老有所乐。因此,在应对具有挑战性的生活问题时,他们有可能通过终极存在目的获得自我安宁。进一步讨论研究结果的实际意义
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引用次数: 1
Psychometric Properties of the Iranian Version of the Invalidating Childhood Environment Scale 伊朗版无效童年环境量表的心理计量特性
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14344
Farima Rahmati, M. Aslzaker, Mohammad Noori, Imaneh Abasi
Objective: To understand the consequences of an invalidating environment, it is essential to have a measurement tool with appropriate statistical properties. Thus, the primary aim of this study was to render the ICES (Invalidating Childhood Environment Scale) into Persian and subsequently evaluate the psychometric attributes of this translated version. Method: Data were collected from 1221 nonclinical participants, including 1053 females and 168 males, who were students at medical universities in Tehran, Iran. Several questionnaires, such as the ICES, CTQ (Childhood Trauma Questionnaire), DTS (Distress Tolerance Scale), BIS-11 (Barratt Impulsiveness Scale), Self-Compassion Questionnaire, Dutch Eating Behavior Questionnaire, and EAT-26 (Eating AttitudesTest) were used in the study. The data sets were investigated through SPSS and R language to evaluate the ICES' reliability and construct validity. Additionally, Item Response Theory (IRT) was employed with the Graded Response Model (GRM) to measure the psychometric properties of each item in terms of difficulty and discrimination parameters. Results: Confirmatory factor analysis indicated that both single-factor and two-factor models fit well for both maternal and paternal versions of the ICES. The internal consistency, as assessed by Cronbach's alpha, was high and satisfactory for both maternal (0.87) and paternal (0.87) versions. Notably, the IRT analysis revealed that item 9 performed poorly in both maternal and paternal versions. Compared to the one-factor model, the two-factor model demonstrated a superior fit. Additionally, the test-retest reliability of the ICES over two months demonstrated good reliability for both maternal and paternal versions (0.98). Divergent and convergent validity analysis revealed a significant negative relationship between childhood invalidation environment and distress tolerance (r = 0.175, P < 0.01) as well as self-compassion (r = 0.142, P < 0.01), which were inversely related to the ICES. Furthermore, there was a considerably positive correlation between the invalidating environment experienced during childhood and impulsivity, as evidenced by r = 0.196 and P < 0.01. Conclusion: This study established the favorable psychometric properties of the Persian version of the ICES, indicating that this version is reliable and valid to assess the Invalidating Childhood Environment in the Iranian population. However, further investigations are warranted to reevaluate its validity and reliability.
目的:要了解无效环境的后果,必须要有一个具有适当统计特性的测量工具。因此,本研究的主要目的是将 ICES(童年失效环境量表)翻译成波斯语,然后对翻译版本的心理测量属性进行评估。研究方法:收集了 1221 名非临床参与者的数据,其中包括 1053 名女性和 168 名男性,他们都是伊朗德黑兰医科大学的学生。研究中使用了几种问卷,如 ICES、CTQ(童年创伤问卷)、DTS(压力耐受量表)、BIS-11(巴拉特冲动量表)、自我同情问卷、荷兰饮食行为问卷和 EAT-26(饮食态度测试)。通过 SPSS 和 R 语言对数据集进行调查,以评估 ICES 的信度和构效度。此外,研究还采用了项目反应理论(IRT)和分级反应模型(GRM)来测量每个项目在难度和区分度参数方面的心理测量特性。研究结果确认性因素分析表明,单因素和双因素模型都很适合母系和父系版本的 ICES。根据 Cronbach's alpha 的评估,母系版本(0.87)和父系版本(0.87)的内部一致性都很高,令人满意。值得注意的是,IRT 分析表明,第 9 项在母方和父方版本中的表现均较差。与单因素模型相比,双因素模型的拟合效果更好。此外,两个月的 ICES 测试再测信度在母方和父方版本中均表现出良好的信度(0.98)。发散效度和聚合效度分析表明,童年无效环境与痛苦容忍度(r = 0.175,P < 0.01)和自我同情(r = 0.142,P < 0.01)之间存在显著的负相关,而这两者与 ICES 呈反比关系。此外,童年时期所经历的无效环境与冲动性之间存在显著的正相关关系,r = 0.196,P < 0.01。结论本研究确定了波斯语版 ICES 的良好心理计量特性,表明该版本在评估伊朗人群的童年无效环境方面是可靠有效的。不过,还需要进一步的调查来重新评估其有效性和可靠性。
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引用次数: 0
Factors Associated with Psychotic and Depressive Symptoms in Methamphetamine Users 与甲基苯丙胺使用者精神病和抑郁症状相关的因素
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14334
Sercan Karabulut
Objective: Methamphetamine use has been recognized as a prominent public health issue, which is associated with psychotic and depressive symptoms. This study aimed to assess factors that show a significant relation with psychotic and depressive symptoms in adults who use methamphetamine. Method: We assessed 95 patients who had used methamphetamine within the last month and were admitted to the outpatient treatment clinic. Evaluation of all patients was carried out through face-to-face interviews, and their symptoms were evaluated using different scales. The Scale for the Assessment of Positive Symptoms and the Scale for the Assessment of Negative Symptoms were employed to assess positive and negative symptoms of psychosis, respectively. Depressive symptoms were measured using the Montgomery-Asberg Depression Rating Scale, while illness severity was evaluated using the Clinical Global Impression- Severity Scale. Additionally, functioning status was assessed using the Functioning Assessment Short Test, and withdrawal severity was measured by employing the Amphetamine Cessation Symptom Assessment Scale. Craving severity was evaluated using the Stimulant Craving Questionnaire, anxiety severity using the Hamilton Anxiety Rating Scale, and insight status using the Schedule for Assessment of Insight Expanded. Results: Among the demographic variables, working with family was associated with lower positive symptoms scores (OR = 6.31, P < 0.05). Parole/probation related admissions were associated with lower positive and depressive symptoms scores (OR = 15.06, P = 0.03; OR = 9.87, P = 0.02). Having suicide attempts, number of suicide attempts, and amount of methamphetamine used were found to show association with higher positive (OR = 13.59, P < 0.01; OR = 2.52, P < 0.05; OR = 3.48, P < 0.05, respectively) and depressive symptoms scores (OR = 10.35, P < 0.001; OR = 2.23, P < 0.01; OR = 2.3, P < 0.05). After adjusting for all variables, clinical impression and insight scores remained significantly associated with positive symptoms scores (AOR = 6.74, P < 0.05; AOR = 2.63, P < 0.001, respectively), while anxiety, amphetamine cessation, and positive symptoms scores remained associated with depressive symptoms scores (AOR = 0.48, P < 0.001; AOR = 0.11, P = 0.003; AOR = 0.36, P = 0.02, respectively). Conclusion: This study appears to be the first to examine the associations between clinical variables and both positive symptoms and depressive symptoms in methamphetamine users. Increased attention should be paid to suicide history, anxiety level, amount of methamphetamine use and loss of insight to provide effective treatment in patients with methamphetamine use.
目的:吸食甲基苯丙胺已被视为一个突出的公共卫生问题,它与精神病和抑郁症状有关。本研究旨在评估与吸食甲基苯丙胺的成年人的精神病和抑郁症状有显著关系的因素。研究方法:我们对 95 名在过去一个月内吸食过甲基苯丙胺并在门诊治疗诊所住院的患者进行了评估。对所有患者的评估都是通过面对面访谈进行的,并使用不同的量表对他们的症状进行评估。阳性症状评估量表和阴性症状评估量表分别用于评估精神病的阳性症状和阴性症状。抑郁症状采用蒙哥马利-阿斯伯格抑郁评定量表(Montgomery-Asberg Depression Rating Scale)进行测量,病情严重程度则采用临床总体印象-严重程度量表(Clinical Global Impression- Severity Scale)进行评估。此外,功能状况采用功能评估简易测试进行评估,戒断严重程度采用安非他明戒断症状评估量表进行测量。渴求的严重程度使用兴奋剂渴求问卷进行评估,焦虑的严重程度使用汉密尔顿焦虑评定量表进行评估,洞察力状况使用洞察力评估表扩展版进行评估。结果显示在人口统计学变量中,与家人合作与阳性症状得分较低有关(OR = 6.31,P < 0.05)。与假释/保释相关的入院情况与积极症状和抑郁症状得分较低有关(OR = 15.06,P = 0.03;OR = 9.87,P = 0.02)。研究发现,自杀未遂、自杀未遂次数和甲基苯丙胺使用量分别与较高的阳性(OR = 13.59,P < 0.01;OR = 2.52,P < 0.05;OR = 3.48,P < 0.05)和抑郁症状评分有关(OR = 10.35,P < 0.001;OR = 2.23,P < 0.01;OR = 2.3,P < 0.05)。对所有变量进行调整后,临床印象和洞察力得分仍与阳性症状得分显著相关(分别为AOR = 6.74,P < 0.05;AOR = 2.63,P < 0.001),而焦虑、苯丙胺戒断和阳性症状得分仍与抑郁症状得分相关(分别为AOR = 0.48,P < 0.001;AOR = 0.11,P = 0.003;AOR = 0.36,P = 0.02)。结论本研究似乎是首次研究甲基苯丙胺吸食者的临床变量与阳性症状和抑郁症状之间的关系。应加强对自杀史、焦虑程度、甲基苯丙胺使用量和洞察力丧失的关注,以便为使用甲基苯丙胺的患者提供有效的治疗。
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引用次数: 0
Comparison of Theory of Mind between Patients with Major Depressive Disorder and Stimulant-Induced Depressive Disorder 重度抑郁障碍患者与兴奋剂诱发抑郁障碍患者的思维理论比较
Q2 Medicine Pub Date : 2023-12-08 DOI: 10.18502/ijps.v19i1.14336
Leila Razeghian Jahromi, Mohammad Ali Tlais, Hassan Kamar, Alireza Jalali
Objective: Theory of mind (ToM) denotes the ability to understand the mental state of others and perceive their unique beliefs and emotions. In this study, we compared ToM between individuals with major depressive disorder (MDD) and stimulant-induced depressive disorder (SIDD). Method: This cross-sectional, causal-comparative study included patients with MDD or SIDD admitted to Ostad Moharary Neuropsychiatric Hospital between January and June 2022. Each diagnosis was confirmed through a semi-structured interview conducted by a single attending psychiatrist according to the DSM-5 criteria. After consecutive sampling of 110 individuals, 51 patients completed the study in each group. Demographic characteristics were recorded, and the Persian version of the revised Reading the Mind in the Eyes Test (RMET) was used to evaluate ToM. Statistical analysis was performed using SPSS v.25, employing the t-test, chi-squared test, linear regression, and analysis of covariance (ANCOVA). Results: Our analysis included 102 subjects (65.7% male) with a mean age of 35.17 ± 7.54 years. The two groups were similar in age, gender, marital status, working status, occupation, economic class, and ethnicity (P > 0.05). The RMET scores were 12.94 ± 4.03 and 11.86 ± 3.15 in the MDD and SIDD groups, respectively (P = 0.135). Almost all patients had low RMET scores (< 22); only two individuals in the MDD group achieved normal scores (22–30). ANCOVA revealed no significant confounding effects between the independent variables. Furthermore, regression analysis revealed that the level of education had a significant linear relationship (β = 0.249) with the RMET score (P = 0.021). Conclusion: Hospitalized patients with MDD and SIDD have similar ToM deficits, as measured by the RMET.
目的:心智理论(ToM)指的是理解他人心理状态并感知其独特信念和情感的能力。在本研究中,我们比较了重度抑郁障碍(MDD)患者和刺激性抑郁障碍(SIDD)患者的心智理论(ToM)。研究方法这项横断面因果比较研究纳入了 2022 年 1 月至 6 月期间在 Ostad Moharary 神经精神病医院住院的 MDD 或 SIDD 患者。每项诊断均由一名精神科主治医生根据 DSM-5 标准进行半结构化访谈确认。经过对 110 人的连续抽样,每组有 51 名患者完成了研究。研究人员记录了患者的人口统计学特征,并使用波斯语版的 "眼中读心测试"(RMET)来评估 ToM。统计分析使用 SPSS v.25,采用 t 检验、卡方检验、线性回归和协方差分析 (ANCOVA)。结果我们的分析包括 102 名受试者(65.7% 为男性),平均年龄为(35.17 ± 7.54)岁。两组受试者在年龄、性别、婚姻状况、工作状况、职业、经济阶层和种族方面相似(P > 0.05)。MDD 组和 SIDD 组的 RMET 评分分别为(12.94 ± 4.03)和(11.86 ± 3.15)(P = 0.135)。几乎所有患者的 RMET 分数都很低(小于 22 分);只有 MDD 组的两名患者达到了正常分数(22-30 分)。方差分析显示,自变量之间没有明显的混杂效应。此外,回归分析表明,教育水平(β = 0.249)与 RMET 分数(P = 0.021)呈显著线性关系。结论根据 RMET 测量,住院的 MDD 和 SIDD 患者具有相似的 ToM 缺陷。
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引用次数: 0
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Iranian Journal of Psychiatry
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