Pub Date : 2021-01-01DOI: 10.4149/CARDIOL_2021_1_10
V. Simovicova, M. Danková, M. Luknár, P. Leśny, V. Lauko, P. Talarcik, E. Goncalvesová
Simovicova V, Dankova M, Luknar M, Lesny P, Lauko V, Talarcik P, Gonçalvesova E. Eosinophil – “a good servant but a bad master”. Cardiology Lett. 2021;30(1):57–61 Abstract. Eosinophilic myocarditis (EM) is a rare form of myocarditis with a very heterogeneous etiology. It is characterized by the presence of eosinophilic infiltrate in the myocardium. The course can vary from an asymptomatic clinical picture to life-threatening conditions. We describe a case of a 29-year-old patient with a history of bronchial asthma hospitalized for chestpain and manifesting heart failure. A moderate decrease of ejection fraction of the undilated left ventricle chamber was found. High levels of troponin, NTproBNP and eosinophilia were present in the laboratory findings. By endomyocardial biopsy we confirmed the presence of an eosinophilic infiltrate with a histological pattern of myocarditis. We did not confirm clonal proliferation of eosinophils. Corticoid therapy was initiated. After a week we observed normalization of eosinophils and a decrease in cardiac specific enzymes. Different types of ventricular tachycardias, which required multiple external defibrilation, occured during treatment. An ICD was implanted in the secondary prevention of sudden cardiac death. Ventricular arrhythmias have been stabilized by a combination of pharmacotherapy and individualized programming of ICD functions. Control biopsy was without histological finding of myocarditis. Left ventricular ejection fraction improved by 10%: the patient has been asymptomatic. Eosinophilic myocarditis is a rare disease but with poor prognosis in the acute phase. With the presence of eosinophilia in peripheral blood, this potential cause of acute heart failure should also be considered. Clear diagnosis must be confirmed by endomyocardial biopsy. The basis of treatment is corticoid therapy, which positively affects survival. Fig. 4, Tab. 1, Ref. 13, on-line full text (Free, PDF) www.cardiologyletters.sk
Simovicova V, Dankova M, Luknar M, Lesny P, Lauko V, Talarcik P, gonalalvesova E.嗜酸性细胞-“好仆人，坏主人”。心脏病杂志，2021;30(1):57-61嗜酸性心肌炎(EM)是一种罕见的形式的心肌炎非常异质性的病因。其特点是心肌中存在嗜酸性粒细胞浸润。病程可以从无症状的临床表现到危及生命的情况。我们描述一个病例29岁的患者支气管哮喘病史住院胸痛和表现心力衰竭。未扩张左心室的射血分数有中度下降。高水平的肌钙蛋白，NTproBNP和嗜酸性粒细胞存在于实验室结果。通过心肌内膜活检，我们证实存在嗜酸性粒细胞浸润，组织学模式为心肌炎。我们没有证实嗜酸性粒细胞的克隆性增殖。开始皮质激素治疗。一周后，我们观察到嗜酸性粒细胞的正常化和心脏特异性酶的减少。治疗期间出现了不同类型的室性心动过速，需要多次体外除颤。在心脏性猝死二级预防中植入ICD。通过药物治疗和ICD功能的个性化编程相结合，室性心律失常已经稳定下来。对照组活检未发现心肌炎。左心室射血分数提高10%:患者无症状。嗜酸性心肌炎是一种罕见的疾病，急性期预后较差。随着外周血中嗜酸性粒细胞增多，急性心力衰竭的潜在原因也应予以考虑。明确的诊断必须通过心内膜肌活检证实。治疗的基础是皮质激素治疗，它对生存有积极的影响。图4，表1，参考文献13，在线全文(免费，PDF) www.cardiologyletters.sk
{"title":"Eozinofil – „dobrý sluha, zlý pán“ / Eosinophil – “a good servant but a bad master”","authors":"V. Simovicova, M. Danková, M. Luknár, P. Leśny, V. Lauko, P. Talarcik, E. Goncalvesová","doi":"10.4149/CARDIOL_2021_1_10","DOIUrl":"https://doi.org/10.4149/CARDIOL_2021_1_10","url":null,"abstract":"Simovicova V, Dankova M, Luknar M, Lesny P, Lauko V, Talarcik P, Gonçalvesova E. Eosinophil – “a good servant but a bad master”. Cardiology Lett. 2021;30(1):57–61 Abstract. Eosinophilic myocarditis (EM) is a rare form of myocarditis with a very heterogeneous etiology. It is characterized by the presence of eosinophilic infiltrate in the myocardium. The course can vary from an asymptomatic clinical picture to life-threatening conditions. We describe a case of a 29-year-old patient with a history of bronchial asthma hospitalized for chestpain and manifesting heart failure. A moderate decrease of ejection fraction of the undilated left ventricle chamber was found. High levels of troponin, NTproBNP and eosinophilia were present in the laboratory findings. By endomyocardial biopsy we confirmed the presence of an eosinophilic infiltrate with a histological pattern of myocarditis. We did not confirm clonal proliferation of eosinophils. Corticoid therapy was initiated. After a week we observed normalization of eosinophils and a decrease in cardiac specific enzymes. Different types of ventricular tachycardias, which required multiple external defibrilation, occured during treatment. An ICD was implanted in the secondary prevention of sudden cardiac death. Ventricular arrhythmias have been stabilized by a combination of pharmacotherapy and individualized programming of ICD functions. Control biopsy was without histological finding of myocarditis. Left ventricular ejection fraction improved by 10%: the patient has been asymptomatic. Eosinophilic myocarditis is a rare disease but with poor prognosis in the acute phase. With the presence of eosinophilia in peripheral blood, this potential cause of acute heart failure should also be considered. Clear diagnosis must be confirmed by endomyocardial biopsy. The basis of treatment is corticoid therapy, which positively affects survival. Fig. 4, Tab. 1, Ref. 13, on-line full text (Free, PDF) www.cardiologyletters.sk","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4149/CARDIOL_2021_1_7
M. Labudová, J. Beňačka, I. Zámbojová
and of erectile dysfunction in patients with Abstract . Objective : To monitor possible changes in the incidence and severity of erectile dysfunction (ED) in hypertensive patients in relation to the targeted intervention by a nurse aimed at adopting the correct principles of lifestyle of a hypertensive patient. Methods: In a group of randomly enrolled 200 patients aged 40 to 70 years, the questionnaire gathered data on the incidence and severity of erectile dysfunction as well as on the adherence to the correct principles of lifestyle and quality of life. Data collection was repeated after a year, while in half of the patients a nurse performed a periodic targeted intervention during the year. Results: In hypertensive patients with organ complications (previous myocardial infarction, confirmed coronary artery disease, stroke), there was a higher incidence of moderate and severe erectile dysfunction compared to hypertensive patients without organ complications. In the groups without a nurse-intervention, we observed an 18% increase in the number of patients with erectile dysfunction in the group without organ complications and 37% in the group with organ complications, after one year. Conclusion: The results confirmed the assumption of a positive effect of targeted nursing interventions aimed at the adherence to correct lifestyle on the quality of life and within it the manifestations of erectile dysfunction. Tab. 5, Ref. 14, on-line full text (Free, PDF) www.cardiologyletters.sk
{"title":"Výskyt a závažnosť erektilnej dysfunkcie u pacientov s hypertenziou / Incidence and severity of erectile dysfunction in patients with hypertension","authors":"M. Labudová, J. Beňačka, I. Zámbojová","doi":"10.4149/CARDIOL_2021_1_7","DOIUrl":"https://doi.org/10.4149/CARDIOL_2021_1_7","url":null,"abstract":"and of erectile dysfunction in patients with Abstract . Objective : To monitor possible changes in the incidence and severity of erectile dysfunction (ED) in hypertensive patients in relation to the targeted intervention by a nurse aimed at adopting the correct principles of lifestyle of a hypertensive patient. Methods: In a group of randomly enrolled 200 patients aged 40 to 70 years, the questionnaire gathered data on the incidence and severity of erectile dysfunction as well as on the adherence to the correct principles of lifestyle and quality of life. Data collection was repeated after a year, while in half of the patients a nurse performed a periodic targeted intervention during the year. Results: In hypertensive patients with organ complications (previous myocardial infarction, confirmed coronary artery disease, stroke), there was a higher incidence of moderate and severe erectile dysfunction compared to hypertensive patients without organ complications. In the groups without a nurse-intervention, we observed an 18% increase in the number of patients with erectile dysfunction in the group without organ complications and 37% in the group with organ complications, after one year. Conclusion: The results confirmed the assumption of a positive effect of targeted nursing interventions aimed at the adherence to correct lifestyle on the quality of life and within it the manifestations of erectile dysfunction. Tab. 5, Ref. 14, on-line full text (Free, PDF) www.cardiologyletters.sk","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70878487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4149/CARDIOL_2021_1_9
M. Hulman, M. Beňa, I. Gasparovic, A. Ftacnikova, P. Artemiou
Hulman M, Bena M, Gasparovic I, Ftacnikova A, Artemiou P. Transcatheter mitral valve replacement with Tendyne valve: The first two cases in Slovakia Cardiology Lett. 2021;30(1):53–56 Transcatheter mitral valve replacement (TMVR) with the Tendyne mitral valve has emerged as a novel potential therapy for patients with severe mitral valve disease who are unsuitable candidates for conventional surgery and transcatheter mitral repair with MitraClip. In this communication we present the first two cases that were performed in Slovakia and the V4 countries. Two surgically high risk female patients 78 and 79 years old respectively (EuroScore II 7.8% and 7.4% respectively) also unsuitable candidates for transcatheter mitral repair with MitraClip, underwent transapical TMVR with the Tendyne valve. Both procedures were successful: one of the patients two months after the procedure is doing well, the other patient had a complicated postoperative course and died on postoperative day 4. Moreover we present a brief description of the valve, and of the deployment technique, and an overview of the major clinical studies. Fig. 3, Ref. 7, on-line full text (Free, PDF) www.cardiologyletters.sk
Hulman M, Bena M, Gasparovic I, Ftacnikova A, Artemiou P.经导管二尖瓣置换术与Tendyne二尖瓣:斯洛伐克心脏病杂志的前两例，2021;30(1):53-56经导管二尖瓣置换术(TMVR)与Tendyne二尖瓣已成为不适合常规手术和经导管二尖瓣修复的严重二尖瓣疾病患者的一种新的潜在治疗方法。在本通讯中，我们介绍了在斯洛伐克和V4国家进行的前两个病例。2例手术高危女性患者，年龄分别为78岁和79岁(EuroScore II分别为7.8%和7.4%)，同样不适合使用MitraClip进行经导管二尖瓣修复，接受了带Tendyne瓣膜的经尖顶TMVR。两次手术都很成功:其中一名患者在手术两个月后恢复良好，另一名患者术后过程复杂，于术后第4天死亡。此外，我们还简要介绍了瓣膜，部署技术，并概述了主要的临床研究。图3，参考文献7，在线全文(免费，PDF) www.cardiologyletters.sk
{"title":"Transcatheter mitral valve replacement with Tendyne valve: \u0000The first two cases in Slovakia","authors":"M. Hulman, M. Beňa, I. Gasparovic, A. Ftacnikova, P. Artemiou","doi":"10.4149/CARDIOL_2021_1_9","DOIUrl":"https://doi.org/10.4149/CARDIOL_2021_1_9","url":null,"abstract":"Hulman M, Bena M, Gasparovic I, Ftacnikova A, Artemiou P. Transcatheter mitral valve replacement with Tendyne valve: The first two cases in Slovakia Cardiology Lett. 2021;30(1):53–56 Transcatheter mitral valve replacement (TMVR) with the Tendyne mitral valve has emerged as a novel potential therapy for patients with severe mitral valve disease who are unsuitable candidates for conventional surgery and transcatheter mitral repair with MitraClip. In this communication we present the first two cases that were performed in Slovakia and the V4 countries. Two surgically high risk female patients 78 and 79 years old respectively (EuroScore II 7.8% and 7.4% respectively) also unsuitable candidates for transcatheter mitral repair with MitraClip, underwent transapical TMVR with the Tendyne valve. Both procedures were successful: one of the patients two months after the procedure is doing well, the other patient had a complicated postoperative course and died on postoperative day 4. Moreover we present a brief description of the valve, and of the deployment technique, and an overview of the major clinical studies. Fig. 3, Ref. 7, on-line full text (Free, PDF) www.cardiologyletters.sk","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70878068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_2_2
R. Hatala
. The aim of the presented proposal is to counteract the dramatic spread of the COVID-19 disease and to target reduction of its high case fatality rate by risk stratification during the early phases of the disease. Two key factors have contributed to the catastrophic extent of the disease in several countries: – Most of the known COVID-19 hotspots were locally preceded by massive gatherings of up to several hundred-thousand people (sporting events, religious pilgrimages etc.). – Widespread, mostly subclinical infection of health care workers (HCW) in the hospitals of the hotspot regions inabled a crucial dramatic virus transmission to elderly population. Replication of the former factor for virus spread is actually stoped by measures preventing people from as-sembling. However, HCW represent at least 11% of the total infected population and they still suffer from suboptimal availability of protective gear. The following targeted steps are proposed: the several biomarkers (mainly parameters of inflammation, thrombophilia, and organ damage – heart and liver) aiming at early risk stratification. Thus, this proposal represents a complementary sustainable strategy to general anti-epidemic measures it could be of help to achieve 3 crucial goals: 1. To minimize virus spread in and from health-care facilities; 2. To protect HCW; 3. To identify COVID-19 patients at high risk for adverse, frequently lethal, outcome. Tab. 1, Ref. 17, on-line full
{"title":"Návrh protiepidemického postupu cieleného na zdravotníkov a pacientov pri epidémii COVID-19 na Slovensku / Health-care workers and patient focused proposal for anti-epidemic management during the COVID-19 epidemics in Slovakia","authors":"R. Hatala","doi":"10.4149/cardiol_2020_2_2","DOIUrl":"https://doi.org/10.4149/cardiol_2020_2_2","url":null,"abstract":". The aim of the presented proposal is to counteract the dramatic spread of the COVID-19 disease and to target reduction of its high case fatality rate by risk stratification during the early phases of the disease. Two key factors have contributed to the catastrophic extent of the disease in several countries: – Most of the known COVID-19 hotspots were locally preceded by massive gatherings of up to several hundred-thousand people (sporting events, religious pilgrimages etc.). – Widespread, mostly subclinical infection of health care workers (HCW) in the hospitals of the hotspot regions inabled a crucial dramatic virus transmission to elderly population. Replication of the former factor for virus spread is actually stoped by measures preventing people from as-sembling. However, HCW represent at least 11% of the total infected population and they still suffer from suboptimal availability of protective gear. The following targeted steps are proposed: the several biomarkers (mainly parameters of inflammation, thrombophilia, and organ damage – heart and liver) aiming at early risk stratification. Thus, this proposal represents a complementary sustainable strategy to general anti-epidemic measures it could be of help to achieve 3 crucial goals: 1. To minimize virus spread in and from health-care facilities; 2. To protect HCW; 3. To identify COVID-19 patients at high risk for adverse, frequently lethal, outcome. Tab. 1, Ref. 17, on-line full","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_2_5
P. Michálek, S.B. Hatahet,M. Svetlošák, P. Margitfalvi, I. Waczulíková, S. Trnovec, A. Böhm, O. Beňačka, R. Hatala
{"title":"Transmurálna disperzia komorovej repolarizácie a jej vzťah k výskytu malígnych komorových arytmií u pacientov po infarkte myokardu / Transmural dispersion of ventricular repolarization and its relation to incidence of malignant ventricular arrhythmias in","authors":"P. Michálek, S.B. Hatahet,M. Svetlošák, P. Margitfalvi, I. Waczulíková, S. Trnovec, A. Böhm, O. Beňačka, R. Hatala","doi":"10.4149/cardiol_2020_2_5","DOIUrl":"https://doi.org/10.4149/cardiol_2020_2_5","url":null,"abstract":"","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"07 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_4_6
M. Dúbrava, F. Németh, T. Drobná, L. Gerlich
. Atrial fibrillation (AF) is the most frequent arrhythmia in seniors and can negatively influence their quality of life. In the “Slovak audit of Atrial FIbrillation in Seniors” study (4252 consecutive patients with AF aged ≥ 65 years [mean age 80.9 years], hospitalised during 2.5 years in 4 acute geriatric departments) serum potassium level was one of the analysed parameters. We proved that both hypo- and hyperkalemia are quite frequent. This can be related to the drugs used as well (we analysed 9 drugs / drug groups with the potential known to influence kalemia). We could not prove an association between diuretics and hypokalemia. Neither did a cumulation of drugs with hyperkalemic potential lead to an increased frequency of hyperkalemia: on the contrary, they significantly decreased this risk at discharge. We proved the expected mild increase in risk of hyperkalemia under sporinolactone medication, but only at admission (OR 2.06), at discharge spironolactone was “protective” against hyperkalemia. Surprisingly we revealed an association between low molecular weight heparin (at discharge) and hyperkalemia (OR 2.01), and between non-steroidal anti-inflammatory drugs (at admission) and hyperkalemia (OR 1.76). Thus in real (hospital) life we can control the expected threats of potassium disturbances induced by diuretics and drugs influencing the renin – angiotensin – aldosterone system in an effective way. This is confirmed also by the finding that potassium dysbalance occurred in all investigated drugs / drug groups less frequently at discharge than at admission. Kalemia and its disturbances can be easily and cheaply tested and are well treatable. Appropriate attention to them should be paid in seniors (with AF) during prehospital and hospital health care delivery. Tab. 1, Ref. 20, on-line full text (Free, PDF) www.cardiologyletters.sk
{"title":"Dyskaliémie a niektoré liečivá u seniorov s fibriláciou predsiení (údaje zo štúdie SAFIS) / Potassium disturbances and some drugs in seniors with atrial fibrillation (data from SAFIS study)","authors":"M. Dúbrava, F. Németh, T. Drobná, L. Gerlich","doi":"10.4149/cardiol_2020_4_6","DOIUrl":"https://doi.org/10.4149/cardiol_2020_4_6","url":null,"abstract":". Atrial fibrillation (AF) is the most frequent arrhythmia in seniors and can negatively influence their quality of life. In the “Slovak audit of Atrial FIbrillation in Seniors” study (4252 consecutive patients with AF aged ≥ 65 years [mean age 80.9 years], hospitalised during 2.5 years in 4 acute geriatric departments) serum potassium level was one of the analysed parameters. We proved that both hypo- and hyperkalemia are quite frequent. This can be related to the drugs used as well (we analysed 9 drugs / drug groups with the potential known to influence kalemia). We could not prove an association between diuretics and hypokalemia. Neither did a cumulation of drugs with hyperkalemic potential lead to an increased frequency of hyperkalemia: on the contrary, they significantly decreased this risk at discharge. We proved the expected mild increase in risk of hyperkalemia under sporinolactone medication, but only at admission (OR 2.06), at discharge spironolactone was “protective” against hyperkalemia. Surprisingly we revealed an association between low molecular weight heparin (at discharge) and hyperkalemia (OR 2.01), and between non-steroidal anti-inflammatory drugs (at admission) and hyperkalemia (OR 1.76). Thus in real (hospital) life we can control the expected threats of potassium disturbances induced by diuretics and drugs influencing the renin – angiotensin – aldosterone system in an effective way. This is confirmed also by the finding that potassium dysbalance occurred in all investigated drugs / drug groups less frequently at discharge than at admission. Kalemia and its disturbances can be easily and cheaply tested and are well treatable. Appropriate attention to them should be paid in seniors (with AF) during prehospital and hospital health care delivery. Tab. 1, Ref. 20, on-line full text (Free, PDF) www.cardiologyletters.sk","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_4_10
M. Ivančíková, J. Sipka, M. Škamla, G. Kaliska
. Left atrial thrombus may be detected by transoesophageal echocardiography in patients with atrial fibrillation despite continuous anticoagulation therapy. We would like to introduce a case report of a patient treated in our hospital, in whom ischemic stroke occurred despite effective anticoagulant treatment. Fig. 3, Ref. 11, on-line full text (Free, PDF) www.cardiologyletters.sk
{"title":"Left atrial thrombus despite continuous oral anticoagulant therapy","authors":"M. Ivančíková, J. Sipka, M. Škamla, G. Kaliska","doi":"10.4149/cardiol_2020_4_10","DOIUrl":"https://doi.org/10.4149/cardiol_2020_4_10","url":null,"abstract":". Left atrial thrombus may be detected by transoesophageal echocardiography in patients with atrial fibrillation despite continuous anticoagulation therapy. We would like to introduce a case report of a patient treated in our hospital, in whom ischemic stroke occurred despite effective anticoagulant treatment. Fig. 3, Ref. 11, on-line full text (Free, PDF) www.cardiologyletters.sk","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_4_2
R. Hatala, G. Kaliská, P. Margitfalvi, A. Bystrianský, S. Mišíková, L. Urbán, P. Hlivák
Liečba pomocou implantovateľných kardioverterov-defibrilátorov (ICD) predstavuje intervenčný terapeutický prístup pre pacientov s dokázaným alebo predpokladaným vysokým rizikom potenciálne život ohrozujúcich komorových arytmií. Tieto prístroje kontinuálne monitorujú elektrickú činnosť srdca a dokážu ukončiť potenciálne fatálne komorové tachykardie alebo komorovú fibriláciu. Cieľom predkladaného konsenzuálneho dokumentu je zabezpečiť adekvátnu kvalitu indikácií a dlhodobého komplexného kardiologického manažmentu pacientov s vysokým rizikom náhlej arytmickej smrti, u ktorých sa zvažuje implantácia ICD. Dôležité je, aby sa táto liečba realizovala na pracovisku s reálne dostupnými možnosťami komplexnej invazívnej aj neinvazívnej diagnostiky a manažmentu štrukturálneho alebo genetického ochorenia srdca, ktoré viedlo k vysokému riziku malígnych komorových arytmií ako indikácie k implantácii ICD.
{"title":"Požiadavky na špecializované kardiologické pracovisko oprávnené na implantáciu kardioverterov-defibrilátorov (ICD) v Slovenskej republike. Konsenzus Slovenskej asociácie srdcových arytmií","authors":"R. Hatala, G. Kaliská, P. Margitfalvi, A. Bystrianský, S. Mišíková, L. Urbán, P. Hlivák","doi":"10.4149/cardiol_2020_4_2","DOIUrl":"https://doi.org/10.4149/cardiol_2020_4_2","url":null,"abstract":"Liečba pomocou implantovateľných kardioverterov-defibrilátorov (ICD) predstavuje intervenčný terapeutický prístup pre pacientov s dokázaným alebo predpokladaným vysokým rizikom potenciálne život ohrozujúcich komorových arytmií. Tieto prístroje kontinuálne monitorujú elektrickú činnosť srdca a dokážu ukončiť potenciálne fatálne komorové tachykardie alebo komorovú fibriláciu. Cieľom predkladaného konsenzuálneho dokumentu je zabezpečiť adekvátnu kvalitu indikácií a dlhodobého komplexného kardiologického manažmentu pacientov s vysokým rizikom náhlej arytmickej smrti, u ktorých sa zvažuje implantácia ICD. Dôležité je, aby sa táto liečba realizovala na pracovisku s reálne dostupnými možnosťami komplexnej invazívnej aj neinvazívnej diagnostiky a manažmentu štrukturálneho alebo genetického ochorenia srdca, ktoré viedlo k vysokému riziku malígnych komorových arytmií ako indikácie k implantácii ICD.","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_3_9
R. Steinkamp, J. Radošinská
{"title":"Účasť cytokínov pri srdcovom zlyhávaní / Cytokines in relation to heart failure","authors":"R. Steinkamp, J. Radošinská","doi":"10.4149/cardiol_2020_3_9","DOIUrl":"https://doi.org/10.4149/cardiol_2020_3_9","url":null,"abstract":"","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4149/cardiol_2020_4_9
J. Radošinská, T. Jasenovec, A. Púzserová, J. Krajcir, J. Lacekova, K. Kučerová, T. Kalnovičová, Ľ. Tóthová, Ivona Kovacicova, N. Vrbjar
. Objectives: Rheological properties of blood significantly affect blood flow in large vessels. Changes in macrocirculation contribute to atherogenesis and consequently cardio-vascular diseases. However, blood flow disorders also impair the quality of microcirculation, e.g. in patients with recurrent episodes of cardiac ischemia. Since a negative correlation between plasma vitamin C levels and blood viscosity was found, we focused on the effect of vitamin C on hemorheology in more detail. Considering the important role of erythrocytes in blood rheology, we decided to simultaneously monitor changes in erythrocyte parameters. Methods: Hemorheological parameters were determined by rotational and oscillatory measurements. Regarding erythrocytes, we measured their deformability, nitric oxide production and sodium-potassium pump activity. Results: We observed a beneficial effect of increased vitamin C intake on several hemorheological parameters as well as improvement of erythrocyte deformability, increased nitric oxide production and activity of sodium-potassium pump. No change in oxidative stress and antioxidant protection parameters in plasma was observed. Conclusion: Vitamin C administration to an improvement in several hemorheological parameters in healthy young volunteers. Since improvement in hemorheology may contribute to better quality of macro- and microcirculation, our results suggest a possible benefit of vitamin C administration in patients with impaired hemodynamics. Fig. 4, Ref. 43, on-line full text (Free, PDF) www.cardiologyletters.sk words:
{"title":"Podávanie vitamínu C zlepšuje reológiu plnej krvi u zdravých ľudí / Vitamin C supplementation promotes whole blood rheology in healthy humans","authors":"J. Radošinská, T. Jasenovec, A. Púzserová, J. Krajcir, J. Lacekova, K. Kučerová, T. Kalnovičová, Ľ. Tóthová, Ivona Kovacicova, N. Vrbjar","doi":"10.4149/cardiol_2020_4_9","DOIUrl":"https://doi.org/10.4149/cardiol_2020_4_9","url":null,"abstract":". Objectives: Rheological properties of blood significantly affect blood flow in large vessels. Changes in macrocirculation contribute to atherogenesis and consequently cardio-vascular diseases. However, blood flow disorders also impair the quality of microcirculation, e.g. in patients with recurrent episodes of cardiac ischemia. Since a negative correlation between plasma vitamin C levels and blood viscosity was found, we focused on the effect of vitamin C on hemorheology in more detail. Considering the important role of erythrocytes in blood rheology, we decided to simultaneously monitor changes in erythrocyte parameters. Methods: Hemorheological parameters were determined by rotational and oscillatory measurements. Regarding erythrocytes, we measured their deformability, nitric oxide production and sodium-potassium pump activity. Results: We observed a beneficial effect of increased vitamin C intake on several hemorheological parameters as well as improvement of erythrocyte deformability, increased nitric oxide production and activity of sodium-potassium pump. No change in oxidative stress and antioxidant protection parameters in plasma was observed. Conclusion: Vitamin C administration to an improvement in several hemorheological parameters in healthy young volunteers. Since improvement in hemorheology may contribute to better quality of macro- and microcirculation, our results suggest a possible benefit of vitamin C administration in patients with impaired hemodynamics. Fig. 4, Ref. 43, on-line full text (Free, PDF) www.cardiologyletters.sk words:","PeriodicalId":38919,"journal":{"name":"Cardiology Letters","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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