Pub Date : 2018-12-20DOI: 10.3329/nimcj.v10i1.39331
Mahmuda Hassan, H. Rahman, B. Yasmeen, A. Mukti, Hakimul Haque, M. H. Khan, M. Begum, Sudipta Roy, T. Ahmed, A. U. Ahmed, S. Tabassum, A. Kabir
Thiamine (vitamin B1) was the first B vitamin which has been identified. It serves as a cofactor for several enzymes involved in energy metabolism. The thiamine-dependent enzymes are important for the biosynthesis of neurotransmitters and for the production of reducing substances used in oxidant stress defenses, as well as for the synthesis of pentose used as nucleic acid precursors. Thiamine also plays a central role in cerebral metabolism. There are 2 major manifestations of thiamine deficiency(TD): cardiovascular disease (wet beriberi) and nervous system disease (dry beriberi and Wernicke–Korsakoff syndrome). In wet beriberi, cardiomyopathy with edema and lactic acidosis and in dry beriberi, peripheral neuropathy occurs. Manifestations of Wernicke–Korsakoff syndrome, consist of nystagmus, ophthalmoplegia and ataxia evolving into confusion, retrograde amnesia, cognitive impairment and confabulation. Thiamine deficiency is now very rare in developed countries, but still common in South East Asia specially in developing countries like Bangladesh. It is an important public health problem with potentially fatal consequences. Now a days highly polished rice (Minicut rice) is a popular staple food and other primary dietary sources of thiamine are in short supply. In wet beriberi myocardial disease is prominent which causes a high cardiac output with peripheral vasodilation and warm extremities. Before heart failure, tachycardia, a wide pulse pressure, sweating, warm skin and lactic acidosis develop leading to salt and water retention by the kidneys. The resulting fluid overload leads to edema of the dependent extremities. If it is left untreated the severity of potential outcome will be increased even up to death. Therefore, makes it essential for physician, cardiologists and Paediatrician to have an understanding of this condition and its optimal treatment. Patients on a strict thiamine-deficient diet display a state of severe depletion within 18 days. The most common cause of thiamine deficiency in affluent countries is either alcoholism or malnutrition in nonalcoholic patients especially in children. Treatment by thiamine supplementation is beneficial for diagnostic and therapeutic purposes. Northern International Medical College Journal Vol.10(1) Jul 2018: 351-354
硫胺素(维生素B1)是第一个被确定的B族维生素。它是参与能量代谢的几种酶的辅助因子。依赖硫胺素的酶对神经递质的生物合成和氧化应激防御中使用的还原性物质的产生以及作为核酸前体的戊糖的合成都很重要。硫胺素在大脑代谢中也起着核心作用。硫胺素缺乏症(TD)有两种主要表现:心血管疾病(湿性脚气)和神经系统疾病(干性脚气和Wernicke-Korsakoff综合征)。湿性脚气，心肌病伴水肿和乳酸性酸中毒，干性脚气，周围神经病变发生。Wernicke-Korsakoff综合征的主要表现为眼球震颤、眼麻痹和共济失调，并逐渐发展为精神错乱、逆行性遗忘、认知障碍和虚构。硫胺素缺乏症现在在发达国家非常罕见，但在东南亚仍然很常见，特别是在孟加拉国等发展中国家。这是一个具有潜在致命后果的重要公共卫生问题。如今，精米(Minicut rice)是一种流行的主食，而其他主要膳食来源的硫胺素供应不足。湿性脚气患者心肌疾病突出，引起心排血量高，伴有外周血管舒张和四肢发热。在心力衰竭之前，会出现心动过速、脉压宽、出汗、皮肤发热和乳酸性酸中毒，导致肾脏潴留盐和水。由此产生的液体超载导致依赖肢体的水肿。如果不及时治疗，潜在后果的严重程度将会增加，甚至会导致死亡。因此，对于内科医生、心脏病专家和儿科医生来说，了解这种情况及其最佳治疗方法至关重要。严格缺乏硫胺素饮食的患者在18天内表现出严重的消耗状态。在富裕国家，造成硫胺素缺乏的最常见原因是酗酒或非酗酒患者(尤其是儿童)营养不良。补充硫胺素治疗有利于诊断和治疗目的。北方国际医学院学报Vol.10(1) july 2018: 351-354
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Pub Date : 2018-12-19DOI: 10.3329/nimcj.v10i1.39313
B. Yasmeen
Abstract not available Northern International Medical College Journal Vol.10(1) Jul 2018: 324-325
北方国际医学院学报Vol.10(1) july 2018: 324-325
{"title":"Liver dialysis: a bridge to liver transplantation or regeneration","authors":"B. Yasmeen","doi":"10.3329/nimcj.v10i1.39313","DOIUrl":"https://doi.org/10.3329/nimcj.v10i1.39313","url":null,"abstract":"Abstract not available \u0000Northern International Medical College Journal Vol.10(1) Jul 2018: 324-325","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134427635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/NIMCJ.V9I2.38913
Jotsna Ara Begum, M. Mamun, Akhand Tanzih Sultana, Kamruzzaman, Afm Ashik Imran, Mst Laizuman Nahar
Background :_The spectrum of respiratory illness is wide and includes diseases of upper and lower airways, communicable and non-communicable types. The variation in pattern of morbidity mortality of respiratory illness may be affected by different environmental and climatic variation in different parts of the world.Objective : The present study intended to explore the pattern of respiratory illnesses seen in Bangladeshi children admitted with respiratory illnesses.Methods :_The present prospective observational study was conducted in children up to 12 years of age admitted with acute respiratory illness in pulmonology unit of Dhaka Shishu (Children) Hospitalfrom July 2012 to July 2013. All children between the age limit with acute respiratory illness were included in the study. A standardized questionnaire was formulated and pretested. Then the data were collected through interview by using the questionnaire. Data were analyzed using SPSS version 17.Results : Total 1169 patients were admitted under pulmonology unit during July 2012 to June 2013 among them 324(27.7%) were admitted with respiratory diseases. Among the respiratory diseases Pneumonia (71.2%), Acute Bronchiolitis (20.1%), Bronchial Asthma (4.2%) and TB (2.7%) were commonest. Bronchopneumonia, Acute Bronchiolitis, Bronchial Asthma and TB was common among under 5 children and less common after 5 years. Male were predominate in every cases. Majority of respiratory cases were belonged to poor socioeconomic status. Pneumonia (50.7%) and Acute Bronchiolitis (58.5%) cases were found during autumn and late autumn. Asthma was common during late autumn and winter and Tuberculosis was common throughout the year. Mortality was higher among pneumonia cases.Conclusions :_Respiratory illness contributes most common cause of admission in tertiary care pediatric hospital. Bronchopneumonia is still the commonest respiratory disease with leading cause of mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 308-310
背景:呼吸道疾病的范围很广，包括上呼吸道和下呼吸道疾病、传染性和非传染性疾病。呼吸系统疾病发病率和死亡率模式的变化可能受到世界不同地区不同环境和气候变化的影响。目的:本研究旨在探讨呼吸系统疾病在孟加拉国入院儿童中所见的模式。方法:对2012年7月至2013年7月在达卡Shishu(儿童)医院肺科住院的12岁以下急性呼吸系统疾病患儿进行前瞻性观察研究。所有年龄在急性呼吸道疾病限制范围内的儿童都被纳入研究。制定标准化问卷并进行预测。然后采用问卷调查的方式进行访谈收集数据。数据分析采用SPSS version 17。结果:2012年7月至2013年6月肺科共收治患者1169例，其中呼吸道疾病324例，占27.7%。呼吸道疾病中以肺炎(71.2%)、急性细支气管炎(20.1%)、支气管哮喘(4.2%)和结核病(2.7%)最为常见。支气管肺炎、急性细支气管炎、支气管哮喘和结核病在5岁以下儿童中较为常见，5岁后较少见。所有病例均以男性为主。呼吸道病例以社会经济状况较差者居多。肺炎(50.7%)和急性细支气管炎(58.5%)发生在秋季和深秋。哮喘常见于深秋和冬季，而肺结核全年常见于冬季。肺炎病例的死亡率较高。结论:呼吸系统疾病是三级儿科医院最常见的住院原因。支气管肺炎仍然是最常见的呼吸系统疾病，是导致死亡的主要原因。北方国际医学院学报Vol.9(2) Jan 2018: 308-310
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Pub Date : 2018-11-23DOI: 10.3329/NIMCJ.V9I2.38914
D. Hossain, Shahjahan, Saifullah, K. M. N. Ferdous, M. K. Islam
Background : There are various surgical options for management of anorectal malformations (ARM). Colostomy is a common part of the management of high anorectal malformation in the pediatric population.Objective : The aim of this study was to find out the most common complications after formation of divided sigmoid colostomy.Methods : This prospective observational study was done in the Division of Pediatric Surgery, Bangladesh Institute of Child Health and Dhaka Shishu (Children) Hospital, Dhaka from January 2012 to December 2017. Divided and separated sigmoid colostomy was doneon 116 patients admitted with ARM during this period. Follow up on 2nd, 4th and 8th week after operation was done and in each follow up patients were assessed clinicallyfor wound infection, skin excoriation, prolapse of colostomy, retraction of colostomy and parastomal hernia. If colostomy complications were found then managed as per standard method.Results : The mean age of patients was 2.43±1.29 days and majority of the patients 66 (56.9%) were male.About half of the patients 50(43.1%) had fistula and 21(18.1%) patients had associated anomaly. Among 116 patients 51 (43.97%) developed complications after colostomy. The most common complication was skin excoriation found in 35 (30.2%) patients followed by wound infection in 8(6.9%). Prolapse and retraction of colostomy was found only in 6 (5.17%)and 2 (1.7%) cases respectively. No patient developed parastomal hernia and there was no mortality.Conclusion : Divided and separated sigmoid colostomy provided satisfactory outcome in the management of high anorectal malformation. Skin excoriation was the most common complication and few developed wound infection and prolapse of colostomy.Northern International Medical College Journal Vol.9(2) Jan 2018: 311-314
背景:肛肠畸形(ARM)的治疗有多种手术选择。结肠造口术是治疗小儿高位肛肠畸形的常见方法。目的:探讨乙状结肠分裂造口术后最常见的并发症。方法:本前瞻性观察研究于2012年1月至2017年12月在孟加拉国儿童健康研究所儿科外科和达卡Shishu(儿童)医院进行。在此期间，我们对116例因ARM入院的患者进行了乙状结肠分割和分离造口术。术后第2周、第4周、第8周随访，分别对患者的伤口感染、皮肤擦伤、结肠造口脱垂、造口后缩回、造口旁疝进行临床评估。如果发现结肠造口并发症，则按标准方法处理。结果:患者平均年龄为2.43±1.29 d, 66例患者中以男性居多(56.9%)。50例患者中约有一半(43.1%)存在瘘，21例(18.1%)存在相关异常。116例患者中51例(43.97%)出现结肠造口术后并发症。最常见的并发症是皮肤擦伤35例(30.2%)，其次是伤口感染8例(6.9%)。结肠造口脱垂6例(5.17%)，后缩2例(1.7%)。无患者发生造口旁疝，无死亡病例。结论:分、分离乙状结肠造口术治疗高位肛肠畸形效果满意。皮肤擦伤是最常见的并发症，很少发生伤口感染和结肠造口脱垂。北方国际医学院学报Vol.9(2) Jan 2018: 311-314
{"title":"Divided and Separated Sigmoid Colostomy in Anorectal Malformation : Six Years Experience at Dhaka Shishu Hospital","authors":"D. Hossain, Shahjahan, Saifullah, K. M. N. Ferdous, M. K. Islam","doi":"10.3329/NIMCJ.V9I2.38914","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38914","url":null,"abstract":"Background : There are various surgical options for management of anorectal malformations (ARM). Colostomy is a common part of the management of high anorectal malformation in the pediatric population.Objective : The aim of this study was to find out the most common complications after formation of divided sigmoid colostomy.Methods : This prospective observational study was done in the Division of Pediatric Surgery, Bangladesh Institute of Child Health and Dhaka Shishu (Children) Hospital, Dhaka from January 2012 to December 2017. Divided and separated sigmoid colostomy was doneon 116 patients admitted with ARM during this period. Follow up on 2nd, 4th and 8th week after operation was done and in each follow up patients were assessed clinicallyfor wound infection, skin excoriation, prolapse of colostomy, retraction of colostomy and parastomal hernia. If colostomy complications were found then managed as per standard method.Results : The mean age of patients was 2.43±1.29 days and majority of the patients 66 (56.9%) were male.About half of the patients 50(43.1%) had fistula and 21(18.1%) patients had associated anomaly. Among 116 patients 51 (43.97%) developed complications after colostomy. The most common complication was skin excoriation found in 35 (30.2%) patients followed by wound infection in 8(6.9%). Prolapse and retraction of colostomy was found only in 6 (5.17%)and 2 (1.7%) cases respectively. No patient developed parastomal hernia and there was no mortality.Conclusion : Divided and separated sigmoid colostomy provided satisfactory outcome in the management of high anorectal malformation. Skin excoriation was the most common complication and few developed wound infection and prolapse of colostomy.Northern International Medical College Journal Vol.9(2) Jan 2018: 311-314","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124856321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/nimcj.v9i2.38912
F. Nesa, F. Chowdhury, B. Yasmeen, S. Rahman, N. Begum, Sk Akbar Hossain
Background : Meconium is a dark greenish mass of desquamated cells, mucus, and bile that accumulates in the bowel of a fetus and is typically discharged shortly after birth. Meconium stained amniotic fluid (MSAF) has long been considered to be a bad predictor of fetal outcome.Objective : The aim of this study was to determine if the perinatal outcome is affected by mode of delivery in meconium-stained amniotic fluid.Methodology : This ovservational study was carried out in the department of Obstetrics and Gynaecology in Dhaka Medical College Hospital from July 2016 to June 2017. A total of 204 women who satisfied the inclusion and exclusion criteria were taken for the study. The study group comprised of 102 women admitted in labour and having meconium stained amniotic fluid and 102 women in labour but having clear amniotic fluid were taken as comparision group.Results : The mean age was found 26.6±5.9 years in MSAF group and 26.2±5.0 years in clear liquor group. The mean gestational age was found 38.9±1.8 weeks in MSAF group and 38.5±1.3 weeks in clear liquor group. Risk factors were not statistically significant (p>0.05) between two groups. Forty-one (40.2%) patients had caesarian section in MSAF group and 19(18.6%) in clear liquor group. APGAR score at 1 minute and at 5 minute were statistically significant (p<0.05) between two groups. About 100(98.0%) babies were alive in MSAF group and 101(99.0%) in clear liquor group.Conclusion : Meconium stained amniotic fluid group was associated with higher rate of cesarean delivery, increased need for neonatal resuscitation, increased rate of PIH, pre-eclamsia, Oligohydramnios, IUGR, Post dated pregnancy, Rh incompatibility, GDM and long time hospital stay and hospital mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 304-307
背景:胎便是一种由脱落的细胞、粘液和胆汁组成的深绿色肿块，在胎儿肠道内积聚，通常在出生后不久排出。羊水胎粪染色(MSAF)一直被认为是胎儿结局的不良预测指标。目的:本研究的目的是确定是否围产期结局受分娩方式的影响在粪染色羊水。方法:本观察性研究于2016年7月至2017年6月在达卡医学院附属医院妇产科进行。共有204名符合纳入和排除标准的妇女被纳入研究。研究组以102例产程中羊水有胎粪染色的产妇和102例产程中羊水清澈的产妇为对照组。结果:MSAF组患者平均年龄26.6±5.9岁，清酒组患者平均年龄26.2±5.0岁。MSAF组平均胎龄38.9±1.8周，清酒组平均胎龄38.5±1.3周。两组危险因素比较差异无统计学意义(p>0.05)。MSAF组剖腹产41例(40.2%)，白酒组19例(18.6%)。两组患者1分钟、5分钟APGAR评分比较，差异均有统计学意义(p<0.05)。MSAF组患儿存活100例(98.0%)，白酒组患儿存活101例(99.0%)。结论:羊水胎粪染色组剖宫产率较高，新生儿复苏需求增加，妊高征、先兆子痫、羊水过少、IUGR、超期妊娠、Rh不相容、GDM、住院时间长、住院死亡率高。北方国际医学院学报Vol.9(2) Jan 2018: 304-307
{"title":"Mode of delivery and fetal outcome in meconium stained amniotic fluid in DMCH","authors":"F. Nesa, F. Chowdhury, B. Yasmeen, S. Rahman, N. Begum, Sk Akbar Hossain","doi":"10.3329/nimcj.v9i2.38912","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38912","url":null,"abstract":"Background : Meconium is a dark greenish mass of desquamated cells, mucus, and bile that accumulates in the bowel of a fetus and is typically discharged shortly after birth. Meconium stained amniotic fluid (MSAF) has long been considered to be a bad predictor of fetal outcome.Objective : The aim of this study was to determine if the perinatal outcome is affected by mode of delivery in meconium-stained amniotic fluid.Methodology : This ovservational study was carried out in the department of Obstetrics and Gynaecology in Dhaka Medical College Hospital from July 2016 to June 2017. A total of 204 women who satisfied the inclusion and exclusion criteria were taken for the study. The study group comprised of 102 women admitted in labour and having meconium stained amniotic fluid and 102 women in labour but having clear amniotic fluid were taken as comparision group.Results : The mean age was found 26.6±5.9 years in MSAF group and 26.2±5.0 years in clear liquor group. The mean gestational age was found 38.9±1.8 weeks in MSAF group and 38.5±1.3 weeks in clear liquor group. Risk factors were not statistically significant (p>0.05) between two groups. Forty-one (40.2%) patients had caesarian section in MSAF group and 19(18.6%) in clear liquor group. APGAR score at 1 minute and at 5 minute were statistically significant (p<0.05) between two groups. About 100(98.0%) babies were alive in MSAF group and 101(99.0%) in clear liquor group.Conclusion : Meconium stained amniotic fluid group was associated with higher rate of cesarean delivery, increased need for neonatal resuscitation, increased rate of PIH, pre-eclamsia, Oligohydramnios, IUGR, Post dated pregnancy, Rh incompatibility, GDM and long time hospital stay and hospital mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 304-307","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"25 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120967108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/NIMCJ.V9I2.38910
F. Ferdous, B. Yasmeen, F. Alam, Mahsukur Rahman Chisty, M. Kamal, J. Ali
Background : Autism spectrum disorder (ASD) covers a set of developmental disabilities that can cause significant social, communication, and behavioral challenges.Objective : It was aimed to find out the language problem in Bangladeshi children with Autism spectrum disorder following the neurolinguistics approach.Methodology : A descriptive observational study conducted during the period of April 2014 to December 2014 in the department of Linguistics, University of Dhaka, Bangladesh among the Bangladeshi children aged between 3–12 years. A total of 10 children with normal hearing ability who were diagnosed as ASD according to the diagnostic criteria (DSM- 5 or ICD 10) were enrolled in the study purposively from two tertiary care hospitals of Dhaka city.Results : In this study total 10 children were included and their age range was 3 to 12 years. Male was predominant (90%).Consanguinity of parents was not present in most (90%) cases,60% had positive family history of mental illness, 70% had history of delivery by lower uterine section, 80% of them were term baby. 100% children had delayed speech development, 90% was unable to indicate with index finger, 90% was unable to use noun and pronoun, 90% had repetitive words, 100% had inability to take part in rhymes, 90% was unable to play with symbols, 70% had no eye to eye contact, and 90% had no reciprocal social smile.Conclusion : Language problem in the children with ASD is an under attended problem in Bangladesh. To the authors’ best knowledge this is the first neurolinguistics approach to ASD children in Bangladesh. Further large scale extensive studies would be necessary for better visualization of the extent of the issue.Northern International Medical College Journal Vol.9(2) Jan 2018: 295-299
背景:自闭症谱系障碍(ASD)涵盖了一系列发育障碍，这些障碍会导致重大的社交、沟通和行为挑战。目的:应用神经语言学方法探讨孟加拉裔自闭症谱系障碍儿童的语言问题。方法:2014年4月至2014年12月在孟加拉国达卡大学语言学系对3-12岁的孟加拉国儿童进行描述性观察研究。从达卡市的两家三级医院有目的地招募了10名听力正常且符合诊断标准(DSM- 5或ICD 10)诊断为ASD的儿童。结果:本研究共纳入10例儿童，年龄3 ~ 12岁。男性占多数(90%)。绝大多数(90%)患儿无亲缘关系，60%有精神疾病家族史，70%有下宫产史，80%为足月儿。100%的儿童言语发育迟缓，90%的儿童不能用食指表示，90%的儿童不能使用名词和代词，90%的儿童有重复词语，100%的儿童不能参加押韵，90%的儿童不能玩符号，70%的儿童没有眼神交流，90%的儿童没有相互的社交微笑。结论:在孟加拉国，ASD儿童的语言问题是一个未得到充分关注的问题。据作者所知，这是孟加拉国第一个针对自闭症儿童的神经语言学方法。为了更好地了解这一问题的严重程度，有必要进一步进行大规模广泛的研究。北方国际医学院学报Vol.9(2) Jan 2018: 295-299
{"title":"Language Problem in Bangladeshi Children with Autism spectrum disorder : Observation through a Neurolinguistics Approach","authors":"F. Ferdous, B. Yasmeen, F. Alam, Mahsukur Rahman Chisty, M. Kamal, J. Ali","doi":"10.3329/NIMCJ.V9I2.38910","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38910","url":null,"abstract":"Background : Autism spectrum disorder (ASD) covers a set of developmental disabilities that can cause significant social, communication, and behavioral challenges.Objective : It was aimed to find out the language problem in Bangladeshi children with Autism spectrum disorder following the neurolinguistics approach.Methodology : A descriptive observational study conducted during the period of April 2014 to December 2014 in the department of Linguistics, University of Dhaka, Bangladesh among the Bangladeshi children aged between 3–12 years. A total of 10 children with normal hearing ability who were diagnosed as ASD according to the diagnostic criteria (DSM- 5 or ICD 10) were enrolled in the study purposively from two tertiary care hospitals of Dhaka city.Results : In this study total 10 children were included and their age range was 3 to 12 years. Male was predominant (90%).Consanguinity of parents was not present in most (90%) cases,60% had positive family history of mental illness, 70% had history of delivery by lower uterine section, 80% of them were term baby. 100% children had delayed speech development, 90% was unable to indicate with index finger, 90% was unable to use noun and pronoun, 90% had repetitive words, 100% had inability to take part in rhymes, 90% was unable to play with symbols, 70% had no eye to eye contact, and 90% had no reciprocal social smile.Conclusion : Language problem in the children with ASD is an under attended problem in Bangladesh. To the authors’ best knowledge this is the first neurolinguistics approach to ASD children in Bangladesh. Further large scale extensive studies would be necessary for better visualization of the extent of the issue.Northern International Medical College Journal Vol.9(2) Jan 2018: 295-299","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126180014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/nimcj.v9i2.38908
Bushra Tanzem, S. Tabassum, S. Munshi, M. Jahan
Background : Hepatitis B virus (HBV) infection is one of the major global health problems and this virus has many variants that differ from epidemiological distributions, transmission sources, clinical outcomes, diagnostic assays as well as therapeutic responses. HBV was also divided into 9 different subtypes which has distinct geographical distributions and important for the epidemiological studies and vaccine development.Objective : Bangladesh is an intermediate prevalence region for HBV infection, however, very little is known about the incidence of HBV subtypes in circulation. Therefore, we investigated the HBV subtype distribution in Bangladesh.Method : A small cohort was performed on between March 2014 and August 2017 with 172 HBV DNA positive patients from the BSMMU. From them, 29 HBV DNA samples were isolated for sequencing by Sanger method. HBsAg subtypes were determined by identifying of 226 amino acid (aa) positions in the small surface (S) gene.Result : Our study showed that HBV subtype adrq+ was in 17 (58.6%) isolates, ayw3 in 8 (27.5%), ayw2 in 2 (6.9%) and adw2 in 2 (6.9%) isolates.Conclusion : We conclude subtype adrq+ predominant in Bangladesh. This was followed by ayw3, while adw2 and ayw2 were least dominant. Subtype adw2 and adrq+ strains are found to be related with more complication, therefore, patients infected with these HBV strains need to be careful monitoring to assess their clinical outcome in future.Northern International Medical College Journal Vol.9(2) Jan 2018: 286-290
背景:乙型肝炎病毒(HBV)感染是全球主要的卫生问题之一，这种病毒有许多变体，在流行病学分布、传播来源、临床结果、诊断分析和治疗反应方面各不相同。乙型肝炎病毒还分为9种不同的亚型，它们具有不同的地理分布，对流行病学研究和疫苗开发具有重要意义。目的:孟加拉国是HBV感染的中等流行区，然而，对循环中HBV亚型的发病率知之甚少。因此，我们调查了HBV亚型在孟加拉国的分布。方法:在2014年3月至2017年8月期间，对172名来自BSMMU的HBV DNA阳性患者进行了小队列研究。从中分离29份HBV DNA样本，采用Sanger法进行测序。通过对小表面(S)基因226个氨基酸(aa)位置的鉴定，确定HBsAg亚型。结果:HBV亚型adrq+ 17株(58.6%)，ayw3 8株(27.5%)，ayw2 2株(6.9%)，adw2 2株(6.9%)。结论:adrq+亚型主要发生在孟加拉国。其次是ayw3，而adw2和ayw2最不占优势。发现adw2和adrq+亚型与更多的并发症相关，因此，需要对感染这些HBV毒株的患者进行仔细监测，以评估其临床预后。北方国际医学院学报Vol.9(2) Jan 2018: 286-290
{"title":"Hepatitis B Virus Subtype Distribution in Bangladeshi Chronic Carriers","authors":"Bushra Tanzem, S. Tabassum, S. Munshi, M. Jahan","doi":"10.3329/nimcj.v9i2.38908","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38908","url":null,"abstract":"Background : Hepatitis B virus (HBV) infection is one of the major global health problems and this virus has many variants that differ from epidemiological distributions, transmission sources, clinical outcomes, diagnostic assays as well as therapeutic responses. HBV was also divided into 9 different subtypes which has distinct geographical distributions and important for the epidemiological studies and vaccine development.Objective : Bangladesh is an intermediate prevalence region for HBV infection, however, very little is known about the incidence of HBV subtypes in circulation. Therefore, we investigated the HBV subtype distribution in Bangladesh.Method : A small cohort was performed on between March 2014 and August 2017 with 172 HBV DNA positive patients from the BSMMU. From them, 29 HBV DNA samples were isolated for sequencing by Sanger method. HBsAg subtypes were determined by identifying of 226 amino acid (aa) positions in the small surface (S) gene.Result : Our study showed that HBV subtype adrq+ was in 17 (58.6%) isolates, ayw3 in 8 (27.5%), ayw2 in 2 (6.9%) and adw2 in 2 (6.9%) isolates.Conclusion : We conclude subtype adrq+ predominant in Bangladesh. This was followed by ayw3, while adw2 and ayw2 were least dominant. Subtype adw2 and adrq+ strains are found to be related with more complication, therefore, patients infected with these HBV strains need to be careful monitoring to assess their clinical outcome in future.Northern International Medical College Journal Vol.9(2) Jan 2018: 286-290","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124630572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/nimcj.v9i2.38907
B. Yasmeen
Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 283-285
北方国际医学院学报Vol.9(2) Jan 2018: 283-285
{"title":"Insulin administration Devices–an update","authors":"B. Yasmeen","doi":"10.3329/nimcj.v9i2.38907","DOIUrl":"https://doi.org/10.3329/nimcj.v9i2.38907","url":null,"abstract":"Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 283-285","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131328002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-23DOI: 10.3329/NIMCJ.V9I2.38911
S. Sultana, N. Sultana, S. Ullah, Salma Akter Walida, Parul Akter, F. Ahmed
Background : Amenorrhea means without menstruation. Primary Amenorrhea is the absence of menstruation by 16 years of age in the presence of normal secondary sexual characteristics or by 14 years of age if secondary sexual characteristics have not developed.Objectives : To explore the prevalence of Primary Amenorrhea with etiology in outdoor patient with limited investigation sourcesMethods : This was a cross sectional study conducted at Rupganj Upazila Health Complex (UHC) from January 2014 to June 2016. During this period total 2500 patients attended at Gynae out patient department (OPD). Among them 45 patients was sorted out with Primary amenorrhea. History and physical examination was done for presence or absence of secondary sexual characteristics, external genital abnormalities. Investigations were ultrasonogram (USG), Hormonal test were Follicle stimulating Hormone (FSH), Lutilizing hormones (LH), Serum Prolactin, Thyroid Stimulating Hormone. Karyotyping done. Data were analysed by using SPSS version 20.Result : In our study prevalence of Primary Amenorrhea was 1.8%. Among them infantile uterus was 17.78%, imperforated hymen was 13.33%. Turner mosaic 11.4%, mullarian agenesis 6.66%, gonadal agenesis-4.45%. hypothyroid 8.89%, hyperprolactenemia-8.89%, and 11.11% patients were with positive progesterone challenge test without anatomical and hormonal abnormalities.Conclusion : Considering the study result, Infantile uterus was the most prevalent etiological factor of amenorrhoea followed by imperforated hymen and Turner mosaic.Northern International Medical College Journal Vol.9(2) Jan 2018: 300-303
背景:闭经是指没有月经。原发性闭经是指在有正常第二性征的情况下，在16岁或第二性征没有发育的情况下，在14岁之前没有月经。目的:在调查来源有限的情况下，探讨户外患者原发性闭经的病因流行情况。方法:采用横断面研究方法，于2014年1月至2016年6月在Rupganj Upazila卫生综合医院(UHC)进行。在此期间，共有2500名病人在妇科门诊部就诊。其中45例为原发性闭经。病史和体格检查是否有第二性征、外生殖器异常。超声检查(USG)，激素检查(促卵泡激素(FSH)，利用激素(LH)，催乳素，促甲状腺激素)。核型分析。数据采用SPSS version 20进行分析。结果:原发性闭经的发生率为1.8%。其中婴儿子宫占17.78%，处女膜未穿孔占13.33%。特纳镶嵌11.4%，毛拉发育6.66%，性腺发育4.45%。甲状腺功能减退8.89%，高泌乳症8.89%，孕酮激发试验阳性11.11%，无解剖和激素异常。结论:从研究结果来看，婴儿子宫是闭经最常见的病因，其次是处女膜未穿孔和特纳马赛克。北方国际医学院学报Vol.9(2) 2018年1月:300-303
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Pub Date : 2018-11-23DOI: 10.3329/NIMCJ.V9I2.38915
Mahmuda Hassan, A. Mukti, Hakimul Haque, M. H. Khan, M. Begum, Sudipta Roy, T. Ahmed, A. U. Ahmed, S. Tabassum, A. Kabir, H. Rahman
Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 315-317
《北方国际医学院学报》Vol.9(2) Jan 2018: 315-317
{"title":"Cardiac Beriberi in an infant : An Unforgettable Dis","authors":"Mahmuda Hassan, A. Mukti, Hakimul Haque, M. H. Khan, M. Begum, Sudipta Roy, T. Ahmed, A. U. Ahmed, S. Tabassum, A. Kabir, H. Rahman","doi":"10.3329/NIMCJ.V9I2.38915","DOIUrl":"https://doi.org/10.3329/NIMCJ.V9I2.38915","url":null,"abstract":"Abstract not availableNorthern International Medical College Journal Vol.9(2) Jan 2018: 315-317","PeriodicalId":389586,"journal":{"name":"Northern International Medical College Journal","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115315760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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