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Associations between Tactile Sensory Threshold and Postural Performance and Effects of Healthy Aging and Subthreshold Vibrotactile Stimulation on Postural Outcomes in a Simple Dual Task. 简单双任务中触觉感觉阈值与体位表现的关系及健康老化和阈下触觉振动刺激对体位结果的影响
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-04-10 DOI: 10.1155/2016/9797369
Marius Dettmer, Amir Pourmoghaddam, Beom-Chan Lee, Charles S Layne

Specific activities that require concurrent processing of postural and cognitive tasks may increase the risk for falls in older adults. We investigated whether peripheral receptor sensitivity was associated with postural performance in a dual-task and whether an intervention in form of subthreshold vibration could affect performance. Ten younger (age: 20-35 years) and ten older adults (70-85 years) performed repeated auditory-verbal 1-back tasks while standing quietly on a force platform. Foot sole vibration was randomly added during several trials. Several postural control and performance measures were assessed and statistically analyzed (significance set to α-levels of .05). There were moderate correlations between peripheral sensitivity and several postural performance and control measures (r = .45 to .59). Several postural performance measures differed significantly between older and younger adults (p < 0.05); addition of vibration did not affect outcome measures. Aging affects healthy older adults' performance in dual-tasks, and peripheral sensitivity may be a contributor to the observed differences. A vibration intervention may only be useful when there are more severe impairments of the sensorimotor system. Hence, future research regarding the efficacy of sensorimotor interventions in the form of vibrotactile stimulation should focus on older adults whose balance is significantly affected.

需要同时处理姿势和认知任务的特定活动可能会增加老年人跌倒的风险。我们研究了外周受体敏感性是否与双重任务中的姿势表现有关,以及阈下振动形式的干预是否会影响表现。10名年轻人(年龄20-35岁)和10名老年人(70-85岁)静静地站在一个强制平台上,重复执行听觉-语言-背的任务。在几次试验中随机加入脚底振动。对多项体位控制和性能指标进行评估并进行统计学分析(显著性设为α-水平为0.05)。外周敏感度与几种姿势表现和控制措施之间存在中度相关性(r = 0.45至0.59)。几项体位表现指标在老年人和年轻人之间存在显著差异(p < 0.05);增加震动对结果测量没有影响。衰老影响健康老年人在双重任务中的表现,外周敏感性可能是观察到的差异的一个因素。振动干预可能只有在感觉运动系统有更严重的损伤时才有用。因此,未来关于振动触觉刺激形式的感觉运动干预效果的研究应该集中在平衡受到明显影响的老年人身上。
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引用次数: 13
Do Aging and Tactile Noise Stimulation Affect Responses to Support Surface Translations in Healthy Adults? 衰老和触觉噪声刺激会影响健康成人对支持面翻译的反应吗?
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-04-19 DOI: 10.1155/2016/2941964
Marius Dettmer, Amir Pourmoghaddam, Beom-Chan Lee, Charles S Layne

Appropriate neuromuscular responses to support surface perturbations are crucial to prevent falls, but aging-related anatomical and physiological changes affect the appropriateness and efficiency of such responses. Low-level noise application to sensory receptors has shown to be effective for postural improvement in a variety of different balance tasks, but it is unknown whether this intervention may have value for improvement of corrective postural responses. Ten healthy younger and ten healthy older adults were exposed to sudden backward translations of the support surface. Low-level noise (mechanical vibration) to the foot soles was added during random trials and temporal (response latency) and spatial characteristics (maximum center-of-pressure excursion and anterior-posterior path length) of postural responses were assessed. Mixed-model ANOVA was applied for analysis of postural response differences based on age and vibration condition. Age affected postural response characteristics, but older adults were well able to maintain balance when exposed to a postural perturbation. Low-level noise application did not affect any postural outcomes. Healthy aging affects some specific measures of postural stability, and in high-functioning older individuals, a low-level noise intervention may not be valuable. More research is needed to investigate if recurring fallers and neuropathy patients could benefit from the intervention in postural perturbation tasks.

适当的神经肌肉反应对支持表面的扰动是防止跌倒的关键,但与年龄相关的解剖和生理变化会影响这种反应的适当性和效率。低水平噪声应用于感觉受体已被证明对各种不同平衡任务的姿势改善有效,但尚不清楚这种干预是否对改善纠正姿势反应有价值。10名健康的年轻人和10名健康的老年人暴露于支撑面突然向后平移。在随机试验中加入低水平噪声(机械振动)到脚底,并评估姿势反应的时间(反应潜伏期)和空间特征(最大压力中心偏移和前后路径长度)。采用混合模型方差分析分析不同年龄和振动条件下的体位反应差异。年龄影响姿势反应特征,但老年人在暴露于姿势扰动时能够很好地保持平衡。低水平噪音的应用不影响任何姿势结果。健康的衰老会影响某些特定的姿势稳定性指标,而在高功能的老年人中,低水平的噪音干预可能没有价值。复发性跌倒和神经病变患者是否能从姿势干扰任务的干预中获益还需要更多的研究。
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引用次数: 5
A Study on Mortality Profile among Fifty Plus- (50+-) Population (FPP) of India: A 5-Year Retrospective Study at New Delhi District. 印度 50 岁以上 (50+-) 人口 (FPP) 死亡率概况研究:新德里地区五年回顾性研究。
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-03-03 DOI: 10.1155/2016/6403103
B L Chaudhary, Raghvendra K Vidua, Arvind Kumar, Amrita V Bajaj

Objectives. To find out the mortality profile vis-a-vis different epidemiological factors at the time of autopsy among the 50+-Population. Material and Method. A five-year retrospective evaluation of medicolegal records between 2006 and 2010 was done at Lady Hardinge Medical College, New Delhi. Results. A total of 493 (17.78%) cases belonged to 50+-Population age group out of total 2773 autopsies performed. The proportion of unidentified/unknown persons among this age group was 36.51%. The unnatural and natural causes constituted 44.62% and 55.38% cases, respectively. The unspecified pneumonitis (50.18%) was reported as the commonest cause followed by coronary artery disease and respiratory tuberculosis among natural ones and the transport accident (57.27%) followed by accidental and intentional self-poisoning and exposure to noxious substances and falls among the unnatural ones. Conclusion. The findings reveal that this age group most commonly dies of natural causes rather than the unnatural ones even in autopsy cases. They have definite cure with timely interventions. The study also points out the need to devise the road and home safety measures to reduce mortality among the study population.

目的了解 50 岁以上人群尸检时不同流行病学因素对死亡率的影响。材料和方法。在新德里哈丁格夫人医学院对 2006 年至 2010 年期间的医疗记录进行了为期五年的回顾性评估。结果。在进行的 2773 例尸检中,共有 493 例(17.78%)属于 50 岁以上人群。在这一年龄组中,身份不明/不知名者的比例为 36.51%。非自然和自然原因分别占 44.62% 和 55.38%。据报告,最常见的原因是不明原因的肺炎(50.18%),其次是自然原因中的冠状动脉疾病和呼吸系统结核,以及非自然原因中的交通事故(57.27%),其次是意外和故意自毒、接触有毒物质和跌倒。结论研究结果表明,即使在尸检病例中,该年龄组最常见的死亡原因也是自然死亡,而非非自然死亡。只要及时采取干预措施,他们是可以治愈的。研究还指出,有必要制定道路和家庭安全措施,以降低研究对象的死亡率。
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引用次数: 0
Osteosarcopenic Obesity Syndrome: What Is It and How Can It Be Identified and Diagnosed? 骨质疏松肥胖综合征:它是什么,如何识别和诊断?
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-09-07 DOI: 10.1155/2016/7325973
Jasminka Z Ilich, Owen J Kelly, Julia E Inglis

Conditions related to body composition and aging, such as osteopenic obesity, sarcopenia/sarcopenic obesity, and the newly termed osteosarcopenic obesity (triad of bone muscle and adipose tissue impairment), are beginning to gain recognition. However there is still a lack of definitive diagnostic criteria for these conditions. Little is known about the long-term impact of these combined conditions of osteoporosis, sarcopenia, and obesity in older adults. Many may go undiagnosed and progress untreated. Therefore, the objective of this research is to create diagnostic criteria for osteosarcopenic obesity in older women. The proposed diagnostic criteria are based on two types of assessments: physical, via body composition measurements, and functional, via physical performance measures. Body composition measurements such as T-scores for bone mineral density, appendicular lean mass for sarcopenia, and percent body fat could all be obtained via dual energy X-ray absorptiometry. Physical performance tests: handgrip strength, one-leg stance, walking speed, and sit-to-stand could be assessed with minimal equipment. A score could then be obtained to measure functional decline in the older adult. For diagnosing osteosarcopenic obesity and other conditions related to bone loss and muscle loss combined with obesity, a combination of measures may more adequately improve the assessment process.

与身体成分和衰老有关的疾病,如骨质疏松性肥胖症、肌肉疏松症/肌肉疏松性肥胖症,以及新近被称为骨质疏松性肥胖症(骨骼肌肉和脂肪组织损伤三联症),正开始得到认可。然而,这些病症仍然缺乏明确的诊断标准。人们对老年人骨质疏松症、肌肉疏松症和肥胖症的长期影响知之甚少。许多患者可能得不到诊断和治疗。因此,本研究的目的是为老年妇女的骨质疏松性肥胖症制定诊断标准。建议的诊断标准基于两类评估:通过身体成分测量进行的身体评估和通过身体表现测量进行的功能评估。身体成分测量,如骨矿物质密度的 T 值、肌肉疏松症的关节瘦肉量和体脂百分比,均可通过双能 X 射线吸收测量法获得。体能测试:手握力、单腿站立、行走速度和坐立行走,只需极少的设备即可进行评估。然后就可以得到一个分数来衡量老年人的功能衰退情况。对于诊断骨质疏松性肥胖症和其他与骨质流失和肌肉流失合并肥胖症有关的疾病,综合采用多种测量方法可能会更充分地改善评估过程。
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引用次数: 0
Does Frailty Predict Health Care Utilization in Community-Living Older Romanians? 体弱是否能预测在社区生活的罗马尼亚老年人使用医疗服务的情况?
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-07-17 DOI: 10.1155/2016/6851768
Marinela Olaroiu, Minerva Ghinescu, Viorica Naumov, Ileana Brinza, Wim van den Heuvel

Background. The predictive value of frailty assessment is still debated. We analyzed the predictive value of frailty of independent living elderly. The outcomes variables were visits to the general practitioner, hospital admission, and occurrence of new health problems. Methods. A one-year follow-up study was executed among 215 community-living old Romanians. General practitioners reported the outcome variables of patients, whose frailty was assessed one year before, using the Groningen Frailty Indicator. The predictive validity is analyzed by descriptive and regression analysis. Results. Three-quarters of all participants visited their general practitioner three times more last year and one-third were at least once admitted to a hospital. Patients who scored frail one year before were more often admitted to a hospital. Visits to the general practitioner and occurrence of new health problems were not statistically significant related to frailty scores. The frailty items polypharmacy, social support, and activities in daily living were associated with adverse outcomes. Conclusions. The predictive value of frailty instruments as the Groningen Frailty Indicator is still limited. More research is needed to predict health outcomes, health care utilization, and quality of life of frailty self-assessment instruments. Validation research on frailty in different "environments" is recommended to answer the question to what extent contextual characteristics influence the predictive value.

背景关于虚弱评估的预测价值仍存在争议。我们分析了独立生活老人体弱程度的预测价值。结果变量为全科医生就诊、入院和出现新的健康问题。研究方法我们对 215 名在社区生活的罗马尼亚老人进行了为期一年的跟踪研究。全科医生使用格罗宁根虚弱指标对一年前进行过虚弱评估的患者的结果变量进行了报告。通过描述性分析和回归分析对预测有效性进行了分析。研究结果四分之三的参与者去年曾三次以上就诊于他们的全科医生,三分之一的参与者至少有一次入院治疗。一年前被评为体弱的患者更常入院。看全科医生和出现新的健康问题与虚弱评分没有统计学意义。多药治疗、社会支持和日常生活活动等虚弱项目与不良预后有关。结论是格罗宁根虚弱指标等虚弱工具的预测价值仍然有限。还需要进行更多的研究,以预测虚弱自我评估工具的健康结果、医疗保健利用率和生活质量。建议对不同 "环境 "中的虚弱情况进行验证研究,以回答环境特征在多大程度上影响预测价值的问题。
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引用次数: 0
Bone Mineral Density in the Noninstitutionalized Elderly: Influence of Sociodemographic and Anthropometric Factors. 非住院老年人的骨矿物质密度:社会人口和人体测量因素的影响。
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-04-05 DOI: 10.1155/2016/4946593
Ellen Cristina de Sousa E Silva Araujo, Valéria Pagotto, Erika Aparecida Silveira

Objective. Analysis of bone mineral density (BMD) in the elderly and its associated factors according to sex. Methods. A cross-sectional study is presented herein, with a random sample of 132 noninstitutionalized elderly people. Individuals who did not use diuretics were excluded. BMD was obtained from examination of total body densitometry and its association with sociodemographic variables, lifestyle, anthropometric, and body composition was verified. Results. Mean BMD for men was 1.17 ± 0.12 g/cm(2) and for women was 1.04 ± 0.11 g/cm(2). Higher education was associated with higher BMD values in men (p < 0.05). There was a reduction in BMD in the age group 75-79 years of age in women and over 80 years of age in men (p < 0.05). Underweight was associated with significantly low BMD for both sexes (p < 0.01), while normal weight was associated with low BMD in women (p < 0.001). Discussion. The elderly with low schooling and in older age groups are more probable to also present low BMD. Lower levels of body mass index also indicated towards low BMD.

目的根据性别分析老年人的骨矿物质密度(BMD)及其相关因素。研究方法本文是一项横断面研究,随机抽取了 132 名非住院老人。未使用利尿剂的人被排除在外。通过全身密度测量检查获得 BMD,并验证其与社会人口学变量、生活方式、人体测量和身体成分的关系。结果显示男性的平均 BMD 为 1.17 ± 0.12 g/cm(2),女性为 1.04 ± 0.11 g/cm(2)。教育程度越高,男性的 BMD 值越高(p < 0.05)。女性 75-79 岁年龄组和男性 80 岁以上年龄组的 BMD 值有所下降(p < 0.05)。体重不足与男女的 BMD 值明显偏低有关(p < 0.01),而正常体重与女性的 BMD 值偏低有关(p < 0.001)。讨论。受教育程度低和年龄较大的老年人更有可能出现 BMD 低的情况。体重指数较低也表明 BMD 较低。
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引用次数: 0
Development and Evaluation of an Online Fall-Risk Questionnaire for Nonfrail Community-Dwelling Elderly Persons: A Pilot Study. 非体弱社区居住老年人跌倒风险在线问卷的开发与评估:一项试点研究。
Q2 Medicine Pub Date : 2016-01-01 Epub Date: 2016-05-10 DOI: 10.1155/2016/1520932
Seraina Obrist, Slavko Rogan, Roger Hilfiker

Introduction. Falls are frequent in older adults and may have serious consequences but awareness of fall-risk is often low. A questionnaire might raise awareness of fall-risk; therefore we set out to construct and test such a questionnaire. Methods. Fall-risk factors and their odds ratios were extracted from meta-analyses and a questionnaire was devised to cover these risk factors. A formula to estimate the probability of future falls was set up using the extracted odds ratios. The understandability of the questionnaire and discrimination and calibration of the prediction formula were tested in a cohort study with a six-month follow-up. Community-dwelling persons over 60 years were recruited by an e-mail snowball-sampling method. Results and Discussion. We included 134 persons. Response rates for the monthly fall-related follow-up varied between the months and ranged from low 38% to high 90%. The proportion of present risk factors was low. Twenty-five participants reported falls. Discrimination was moderate (AUC: 0.67, 95% CI 0.54 to 0.81). The understandability, with the exception of five questions, was good. The wording of the questions needs to be improved and measures to increase the monthly response rates are needed before test-retest reliability and final predictive value can be assessed.

介绍。老年人经常跌倒,可能造成严重后果,但对跌倒风险的认识往往很低。调查问卷可能会提高人们对跌倒风险的认识;因此,我们着手构建和测试这样一个问卷。方法。从荟萃分析中提取跌倒风险因素及其比值比,并设计了一份问卷来涵盖这些风险因素。利用提取的比值比建立了一个估计未来跌倒概率的公式。问卷的可理解性、预测公式的辨别性和校正性在6个月随访的队列研究中得到检验。采用电子邮件滚雪球抽样法对60岁以上的社区居民进行调查。结果和讨论。我们纳入了134人。每个月与跌倒相关的随访的应答率各月不同,从38%到90%不等。目前的危险因素所占比例较低。25名参与者报告摔倒。判别中度(AUC: 0.67, 95% CI 0.54 ~ 0.81)。除了五个问题外,可理解性很好。在评估重测信度和最终预测值之前,需要改进问题的措辞,并采取措施提高月回应率。
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引用次数: 19
Subjective Memory Complaint and Depressive Symptoms among Older Adults in Portugal 葡萄牙老年人主观记忆抱怨和抑郁症状
Q2 Medicine Pub Date : 2015-12-31 DOI: 10.1155/2015/296581
M. Sousa, A. Pereira, R. Costa
Background. Older adults report subjective memory complaints (SMCs) but whether these are related to depression remains controversial. In this study we investigated the relationship between the SMCs and depression and their predictors in a sample of old adults. Methods. This cross-sectional study enrolled 620 participants aged 55 to 96 years (74.04 ± 10.41). Outcome measures included a sociodemographic and clinical questionnaire, a SMC scale (QSM), a Geriatric Depression Scale (GDS), a Mini-Mental Status Examination (MMSE), and a Montreal Cognitive Assessment (MoCA). Results. The QSM mean total score for the main results suggests that SMCs are higher in old adults with depressed symptoms, comparatively to nondepressed old adults. The GDS scores were positively associated with QSM but negatively associated with education, MMSE, and MoCA. GDS scores predicted almost 63.4% of variance. Scores on QSM and MoCA are significantly predicted by depression symptomatology. Conclusion. Depression symptoms, lower education level, and older age may be crucial to the comprehension of SMCs. The present study suggested that depression might play a role in the SMCs of the older adults and its treatment should be considered.
背景。老年人报告主观记忆抱怨(SMCs),但这些是否与抑郁症有关仍然存在争议。在这项研究中,我们调查了老年人样本中SMCs与抑郁症及其预测因子之间的关系。方法。这项横断面研究招募了620名年龄在55 ~ 96岁(74.04±10.41)的参与者。结果测量包括社会人口学和临床问卷、SMC量表(QSM)、老年抑郁量表(GDS)、迷你精神状态检查(MMSE)和蒙特利尔认知评估(MoCA)。结果。主要结果的QSM平均总分表明,与非抑郁老年人相比,有抑郁症状的老年人的SMCs更高。GDS得分与QSM呈正相关,与教育程度、MMSE和MoCA呈负相关。GDS分数预测了近63.4%的方差。抑郁症状对QSM和MoCA得分有显著预测作用。结论。抑郁症状、低文化程度和年龄可能对smc的理解至关重要。本研究提示抑郁症可能在老年人的SMCs中起作用,应考虑治疗。
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引用次数: 15
Indirect Fist Percussion of the Liver Is a More Sensitive Technique for Detecting Hepatobiliary Infections than Murphy's Sign 间接拳击肝是一种比墨菲征更灵敏的检测肝胆感染的技术
Q2 Medicine Pub Date : 2015-12-15 DOI: 10.1155/2015/431638
T. Ueda, Eri Ishida
Background. Murphy's sign and Charcot's triad are established clinical findings of acute cholecystitis and cholangitis, respectively, but both show low sensitivity and limited clinical application. We evaluated if indirect fist percussion of the liver improves the efficiency of diagnosing cholecystitis and cholangitis when used as a diagnostic adjunct. Methods. The presence/absence of right upper quadrant (RUQ) tenderness, Murphy's sign, and pain induced by indirect fist percussion of the liver was assessed, and the results were compared with the definite diagnosis based on ultrasound and additional examinations in patients aged over 18 who visited our outpatient clinic with suspected hepatobiliary diseases. Results. Four hundred and eight patients were investigated, and 40 had hepatobiliary infection (acute cholecystitis: 10, acute cholangitis: 28, liver abscess: 1, and hepatic cyst infection: 1). The sensitivity of indirect fist percussion of the liver for diagnosing hepatobiliary infection was 60%, being significantly higher than that of RUQ tenderness (33%) and Murphy's sign (30%), and its specificity was 85%. There was no significant improvement in sensitivity or diagnostic accuracy when Murphy's sign was combined with indirect fist percussion of the liver. Conclusion. Indirect fist percussion-induced liver pain is a useful clinical finding to diagnose hepatobiliary infection, with high-level sensitivity.
背景。Murphy's征象和Charcot's三联征分别是急性胆囊炎和胆管炎的既定临床表现,但两者敏感性较低,临床应用有限。我们评估间接拳击肝作为诊断辅助手段是否能提高胆囊炎和胆管炎的诊断效率。方法。评估右上象限(RUQ)压痛、墨菲征、间接拳击肝脏引起的疼痛是否存在,并将结果与18岁以上门诊就诊的疑似肝胆疾病患者基于超声和附加检查的明确诊断进行比较。结果。共调查248例患者,其中肝胆感染40例(急性胆囊炎10例,急性胆管炎28例,肝脓肿1例,肝囊肿感染1例)。肝间接拳击法诊断肝胆感染的敏感性为60%,明显高于RUQ压痛(33%)和墨菲征(30%),特异性为85%。当墨菲氏征与间接拳击肝相结合时,敏感性和诊断准确性没有显著提高。结论。间接拳击引起的肝痛是诊断肝胆感染的有效临床表现,具有较高的敏感性。
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引用次数: 1
Menopausal Symptoms and Its Correlates: A Study on Tribe and Caste Population of East India. 绝经期症状及其相关因素:对东印度部落和种姓人口的研究
Q2 Medicine Pub Date : 2015-01-01 Epub Date: 2015-07-30 DOI: 10.1155/2015/984767
Doyel Dasgupta, Priyanka Karar, Subha Ray, Nandini Ganguly

Present study aimed to compare the incidence of menopausal problems and concomitants between tribe and caste population. This cross section study was conducted in five villages of West Bengal, a state in the eastern part of India. This study was conducted between two different ethnic groups-one of the "Particularly Vulnerable Tribal Groups (PTG)" of India named as "Lodha" and the other was a Bengali speaking caste population. A total number of 313 participants were finally recruited for this study. Study participants were married, had at least one child, had no major gynaecological problems, and had stopped menstrual bleeding spontaneously for at least 1 year. Additionally, data on sociodemographic status and menstrual and reproductive history were collected using a pretested questionnaire/schedule. Bivariate analyses (chi square test) revealed that significantly more number of caste participants suffered from urinary problems than their tribe counterpart. The reverse trend has been noticed for the frequency of vaginal problems. Multivariate analyses (binary logistic regression) show that sociodemographic variables and menstrual and reproductive history of the present study participants seem to be the concomitants of menopausal symptoms. Tribe and caste study population significantly differed with respect to the estrogen deficient menopausal problems and the concomitants to these problems.

本研究的目的是比较部落和种姓人群的更年期问题及其并发症的发生率。这项横断面研究是在印度东部的西孟加拉邦的五个村庄进行的。这项研究是在两个不同的种族群体之间进行的——一个是印度的“特别脆弱部落群体(PTG)”,被称为“洛达”,另一个是说孟加拉语的种姓人口。最终共有313名参与者被招募到这项研究中。研究参与者已婚,至少有一个孩子,没有重大的妇科问题,并且自发停止月经出血至少一年。此外,使用预先测试的问卷/时间表收集社会人口状况、月经和生殖史的数据。双变量分析(卡方检验)显示,种姓参与者患泌尿系统问题的人数明显多于部落参与者。人们注意到,阴道问题出现的频率与此相反。多变量分析(二元逻辑回归)显示,社会人口统计学变量和本研究参与者的月经和生殖史似乎是更年期症状的伴随物。部落和种姓研究人群在雌激素缺乏的更年期问题及其伴随问题方面存在显著差异。
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引用次数: 15
期刊
Current Gerontology and Geriatrics Research
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