Identifying possible negative side effects of vaccines helps to determine whether benefits outweigh the costs of a medical intervention that claims to prevent a disease. Such a cost-benefit analysis is essential both for vaccine policy as well as informed consent. This study seeks to determine whether the use of the human papillomavirus (HPV) vaccine is related to an increase in high-risk (HR), possibly cancer related, HPV infections. Data from the U.S. National Health and Examination Nutrition Survey reveal a statistically significantly higher percentage of women who received an HPV vaccine carried an HR-HPV than women who did not receive an HPV shot (Rao-Scott Chi-square contrast p-value of 0.002). Vaccine recipients tested positive less frequently for HPVs targeted by the vaccines, but had a higher prevalence of other HR (cancer related) HPVs. The results suggest that a thorough investigation of the effects of HPV vaccines on HR-HPV viruses (and other pathogens) not targeted by them is warranted.
{"title":"Receipt of HPV Vaccine Associated with Increased Prevalence of High-Risk HPV Infections","authors":"Gayle DeLong","doi":"10.56098/ijvtpr.v2i1.28","DOIUrl":"https://doi.org/10.56098/ijvtpr.v2i1.28","url":null,"abstract":"Identifying possible negative side effects of vaccines helps to determine whether benefits outweigh the costs of a medical intervention that claims to prevent a disease. Such a cost-benefit analysis is essential both for vaccine policy as well as informed consent. This study seeks to determine whether the use of the human papillomavirus (HPV) vaccine is related to an increase in high-risk (HR), possibly cancer related, HPV infections. Data from the U.S. National Health and Examination Nutrition Survey reveal a statistically significantly higher percentage of women who received an HPV vaccine carried an HR-HPV than women who did not receive an HPV shot (Rao-Scott Chi-square contrast p-value of 0.002). Vaccine recipients tested positive less frequently for HPVs targeted by the vaccines, but had a higher prevalence of other HR (cancer related) HPVs. The results suggest that a thorough investigation of the effects of HPV vaccines on HR-HPV viruses (and other pathogens) not targeted by them is warranted.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116015652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Operation Warp Speed brought to market in the United States two mRNA vaccines, produced by Pfizer and Moderna. Interim data suggested high efficacy for both of these vaccines, which helped legitimize Emergency Use Authorization (EUA) by the FDA. However, the exceptionally rapid movement of these vaccines through controlled trials and into mass deployment raises multiple safety concerns. In this review we first describe the technology underlying these vaccines in detail. We then review both components of and the intended biological response to these vaccines, including production of the spike protein itself, and their potential relationship to a wide range of both acute and long-term induced pathologies, such as blood disorders, neurodegenerative diseases and autoimmune diseases. Among these potential induced pathologies, we discuss the relevance of prion-protein-related amino acid sequences within the spike protein. We also present a brief review of studies supporting the potential for spike protein “shedding”, transmission of the protein from a vaccinated to an unvaccinated person, resulting in symptoms induced in the latter. We finish by addressing a common point of debate, namely, whether or not these vaccines could modify the DNA of those receiving the vaccination. While there are no studies demonstrating definitively that this is happening, we provide a plausible scenario, supported by previously established pathways for transformation and transport of genetic material, whereby injected mRNA could ultimately be incorporated into germ cell DNA for transgenerational transmission. We conclude with our recommendations regarding surveillance that will help to clarify the long-term effects of these experimental drugs and allow us to better assess the true risk/benefit ratio of these novel technologies.
{"title":"Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19","authors":"S. Seneff, G. Nigh","doi":"10.56098/ijvtpr.v2i1.23","DOIUrl":"https://doi.org/10.56098/ijvtpr.v2i1.23","url":null,"abstract":"Operation Warp Speed brought to market in the United States two mRNA vaccines, produced by Pfizer and Moderna. Interim data suggested high efficacy for both of these vaccines, which helped legitimize Emergency Use Authorization (EUA) by the FDA. However, the exceptionally rapid movement of these vaccines through controlled trials and into mass deployment raises multiple safety concerns. In this review we first describe the technology underlying these vaccines in detail. We then review both components of and the intended biological response to these vaccines, including production of the spike protein itself, and their potential relationship to a wide range of both acute and long-term induced pathologies, such as blood disorders, neurodegenerative diseases and autoimmune diseases. Among these potential induced pathologies, we discuss the relevance of prion-protein-related amino acid sequences within the spike protein. We also present a brief review of studies supporting the potential for spike protein “shedding”, transmission of the protein from a vaccinated to an unvaccinated person, resulting in symptoms induced in the latter. We finish by addressing a common point of debate, namely, whether or not these vaccines could modify the DNA of those receiving the vaccination. While there are no studies demonstrating definitively that this is happening, we provide a plausible scenario, supported by previously established pathways for transformation and transport of genetic material, whereby injected mRNA could ultimately be incorporated into germ cell DNA for transgenerational transmission. We conclude with our recommendations regarding surveillance that will help to clarify the long-term effects of these experimental drugs and allow us to better assess the true risk/benefit ratio of these novel technologies.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123891842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article critically examines the emerging global war on pathogens mimicking the Global War on Terror (GWOT). We draw upon the history of recent wars and the fear-driven narratives aimed at nudging the public toward uncritical acceptance of the new emerging social and economic global order. We adopt Edward Herman and Noam Chomsky’s ‘Propaganda Model’ to describe how mainstream media perform in manufacturing consent to policies that tighten control over populations and degrade rights, agency, and sovereignty. Here we consider the efforts of globalist political actors who seek to co-opt or influence political institutions around the world and position themselves as unelected rulers of an emerging authoritarian order. We argue that agenda-setting media are predisposed to serve elite interests that shape news coverage, bound public debate, and obscure new forms of warfare behind the smokescreen of a manufactured Global War on Pathogens (GWOP). We introduce critical analysis and alternative perspectives, largely marginalized by the mainstream, on the hidden conflicts of interest involved in the demands for full social compliance.
{"title":"Messianic Mad Men, Medicine, and the Media War on Empirical Reality","authors":"D. Broudy, Darwin Hoop","doi":"10.56098/ijvtpr.v2i1.22","DOIUrl":"https://doi.org/10.56098/ijvtpr.v2i1.22","url":null,"abstract":"This article critically examines the emerging global war on pathogens mimicking the Global War on Terror (GWOT). We draw upon the history of recent wars and the fear-driven narratives aimed at nudging the public toward uncritical acceptance of the new emerging social and economic global order. We adopt Edward Herman and Noam Chomsky’s ‘Propaganda Model’ to describe how mainstream media perform in manufacturing consent to policies that tighten control over populations and degrade rights, agency, and sovereignty. Here we consider the efforts of globalist political actors who seek to co-opt or influence political institutions around the world and position themselves as unelected rulers of an emerging authoritarian order. We argue that agenda-setting media are predisposed to serve elite interests that shape news coverage, bound public debate, and obscure new forms of warfare behind the smokescreen of a manufactured Global War on Pathogens (GWOP). We introduce critical analysis and alternative perspectives, largely marginalized by the mainstream, on the hidden conflicts of interest involved in the demands for full social compliance.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"450 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116500884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
No published assessment of revenue variation associated with variance in pediatric vaccine uptake exists. Using data from patients in a pediatric practice that provides full-service with informed consent, we provide a detailed analysis of the financial realities of respecting informed consent and allowing parents to exercise their legal right to refuse some or all pediatric vaccines. The data from a 30-day period of billing were tracked and analyzed via superbills, noting vaccines that were ordered and those that were refused. Considering that other practice income covered all operating expenses; these numbers reflect actual profits (from vaccines given) and losses (from vaccines refused). Patients in the practice exhibited increased refusal of some or all vaccines over a period of approximately ten years. These real-world data show losses would exceed one million US dollars for a practice that bills out just over 3 million (gross revenue). With pediatric administrative overhead running 60–80%, it becomes clear that the financial incentives to vaccinate are now a matter of survival for pediatric practices.
{"title":"Vaccine Practice Payment Schedules Create Perverse Incentives for Unnecessary Medical Procedures – at What Cost to Patients?","authors":"James Lyons-Weiler, Paul Thomas","doi":"10.56098/ijvtpr.v2i1.21","DOIUrl":"https://doi.org/10.56098/ijvtpr.v2i1.21","url":null,"abstract":"No published assessment of revenue variation associated with variance in pediatric vaccine uptake exists. Using data from patients in a pediatric practice that provides full-service with informed consent, we provide a detailed analysis of the financial realities of respecting informed consent and allowing parents to exercise their legal right to refuse some or all pediatric vaccines. The data from a 30-day period of billing were tracked and analyzed via superbills, noting vaccines that were ordered and those that were refused. Considering that other practice income covered all operating expenses; these numbers reflect actual profits (from vaccines given) and losses (from vaccines refused). Patients in the practice exhibited increased refusal of some or all vaccines over a period of approximately ten years. These real-world data show losses would exceed one million US dollars for a practice that bills out just over 3 million (gross revenue). With pediatric administrative overhead running 60–80%, it becomes clear that the financial incentives to vaccinate are now a matter of survival for pediatric practices.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114832669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
COVID-19 public health responses, including lockdowns and diagnostic testing strategies, have had consequences. Economic costs (see the CHD paper in this issue) could reach $16 trillion dollars, 90% of the US annual GDP. While harm to small businesses, unemployment, worsening poverty, death from cancer, increased suicides, social isolation, and restriction of freedom all increase the perceived need for drastic responses from the top, flawed measures are costly. A diagnostic assay[1] of tests for COVID-19 depends for its validity on its sensitivity and specificity assessed in terms of the true positive rate (TPR), false positive rate (FPR), true negative rate (TNR), and false negative rate (FNR) of the assays. In this pandemic, Real Time — Polymerase Chain Reaction (RT-PCR) testing has been relied on for drastic top-down responses (as in shutting down the economy of whole nations or the entire world). Here I focus on false positive results where RT-PCR testing suggests many infections by SARS-CoV-2 where there are none. I show by mathematical modeling how reporting positive results of RT-PCR testing, ones known to be false in a measurable percentage of instances, is at least 40 times more impactful (in a detrimental way) than increasing or decreasing the number of tests conducted. To balance the risks of errors in diagnosis, false positive results must be minimized by validating nucleotide sequences and estimates of viremia to avoid flagging individuals as contagious when they are not.
{"title":"Balance of Risk in COVID-19 Reveals the Extreme Cost of False Positives","authors":"James Lyons-Weiler","doi":"10.56098/ijvtpr.v1i2.15","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.15","url":null,"abstract":"COVID-19 public health responses, including lockdowns and diagnostic testing strategies, have had consequences. Economic costs (see the CHD paper in this issue) could reach $16 trillion dollars, 90% of the US annual GDP. While harm to small businesses, unemployment, worsening poverty, death from cancer, increased suicides, social isolation, and restriction of freedom all increase the perceived need for drastic responses from the top, flawed measures are costly. A diagnostic assay[1] of tests for COVID-19 depends for its validity on its sensitivity and specificity assessed in terms of the true positive rate (TPR), false positive rate (FPR), true negative rate (TNR), and false negative rate (FNR) of the assays. In this pandemic, Real Time — Polymerase Chain Reaction (RT-PCR) testing has been relied on for drastic top-down responses (as in shutting down the economy of whole nations or the entire world). Here I focus on false positive results where RT-PCR testing suggests many infections by SARS-CoV-2 where there are none. I show by mathematical modeling how reporting positive results of RT-PCR testing, ones known to be false in a measurable percentage of instances, is at least 40 times more impactful (in a detrimental way) than increasing or decreasing the number of tests conducted. To balance the risks of errors in diagnosis, false positive results must be minimized by validating nucleotide sequences and estimates of viremia to avoid flagging individuals as contagious when they are not.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"22 12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116858571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A supramolecular paradigm for mitigation and rescue from SARS-COV2 infection is proposed. Similarities between the Sanarelli-Shwartzman phenomenon and biological responses to viral pathogens are considered. Non-enzymatic group transfer catalysis (NGTC) by L-ascorbic acid, the L-ascorbic acid free radical and the 2-O-phosphate substituted L-ascorbic acid derivative are proposed under the ascorbolysis hypothesis to provide a supramolecular basis for mitigating the synergistic toxicity and catalytic mimicry by the environmental toxicants, sodium fluoride, aluminum salts, and silicofluorides in public water supplies. Ascorbolysis is the term we adopt to describe a redox active, hyperconjugated, vinylogous variant of acidolysis. The objective of this paper is to provide a plausible supramolecular basis for mitigation and rescue from well-known environmental toxicity represented by the presence of sodium fluoride, aluminum salts, and silicofluoride species in public water supplies. An overview of the conceptual basis for NGTC by vitamin C during inflammatory states is provided. Controversies concerning the initial oxidation steps and pH-dependent speciation of L-ascorbic acid are addressed. Non-skeletal fluorosis is a serious systemic malady which we propose arises from disruption of hydrogen bond networks and hydrogen bond cooperativity resulting from the marked electronegativity and hydrogen bond accepting ability of fluoride atoms found in NaF and AlFx species. AlFx species have been previously shown to arise in situ spontaneously from NaF, aluminum salts, and silicofluorides often found in toothpastes and “fluoridated” drinking water. AlFx species are thought to act as isosteric mimics of biophosphates during group transfers of phosphoryl moieties. We propose that catalytic mimicry by AlFx species inhibits postulated non-enzymatic kinase-like and RNA polymerase-like function of the AA-2P derivative during inflammatory states. We describe how NGTC by L-ascorbic acid is likely to be disrupted by AlFx and sodium fluoride of a specific H3-O2 intramolecular hydrogen bond in L-ascorbic acid, the L-ascorbic acid free radical, and their 2-O-substituted derivatives, which are necessary for NGTC in the moderately acidic, mildly oxidative, relatively hydrophobic microenvironment which typify inflammatory states. Suggestions are made to achieve less variation in results of large randomized clinical trials (RCTs) seeking to validate use of high-dose intravenous vitamin C in critical care and cancer settings.
提出了一种缓解和拯救SARS-COV2感染的超分子范式。Sanarelli-Shwartzman现象和对病毒病原体的生物反应之间的相似性被考虑。在抗坏血酸分解假说下,提出了l -抗坏血酸、l -抗坏血酸自由基和2- o -磷酸取代l -抗坏血酸衍生物的非酶基转移催化(NGTC),为减轻公共供水中环境毒物、氟化钠、铝盐和氟化硅的协同毒性和催化模仿提供了超分子基础。抗坏血溶解是我们用来描述酸解的氧化还原活性,高共轭,葡萄状变体的术语。本文的目的是提供一个合理的超分子基础,以减轻和拯救众所周知的环境毒性,以公共供水中氟化钠、铝盐和氟化硅的存在为代表。本文概述了炎症状态下维生素C介导NGTC的概念基础。关于l -抗坏血酸的初始氧化步骤和ph依赖性物种的争议被解决。非骨性氟中毒是一种严重的全身性疾病,我们认为它是由于NaF和AlFx中氟原子的明显电负性和氢键接受能力导致氢键网络和氢键协同性的破坏而引起的。先前已经证明,氟化铝是由NaF、铝盐和氟化硅在牙膏和“氟化”饮用水中自然产生的。在磷酸基基团转移过程中,AlFx物种被认为是生物磷酸盐的等构模拟物。我们提出,在炎症状态下,AlFx物种的催化模仿抑制了假设的AA-2P衍生物的非酶激酶样和RNA聚合酶样功能。我们描述了AlFx和氟化钠如何破坏l -抗坏血酸中特定的H3-O2分子内氢键、l -抗坏血酸自由基及其2- o取代衍生物,这是NGTC在中酸性、轻度氧化、相对疏水的微环境中所必需的,这些微环境是典型的炎症状态。为了验证在重症监护和癌症环境中使用大剂量静脉注射维生素C的有效性,建议在大型随机临床试验(rct)中减少结果差异。
{"title":"Vitamin C Mitigating and Rescuing from Synergistic Toxicity: Sodium Fluoride, Silicofluorides, Aluminum Salts, Electromagnetic Pollution, and SARS-CoV-2","authors":"R. Davidson, T. Winey","doi":"10.56098/ijvtpr.v1i2.12","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.12","url":null,"abstract":"A supramolecular paradigm for mitigation and rescue from SARS-COV2 infection is proposed. Similarities between the Sanarelli-Shwartzman phenomenon and biological responses to viral pathogens are considered. Non-enzymatic group transfer catalysis (NGTC) by L-ascorbic acid, the L-ascorbic acid free radical and the 2-O-phosphate substituted L-ascorbic acid derivative are proposed under the ascorbolysis hypothesis to provide a supramolecular basis for mitigating the synergistic toxicity and catalytic mimicry by the environmental toxicants, sodium fluoride, aluminum salts, and silicofluorides in public water supplies. Ascorbolysis is the term we adopt to describe a redox active, hyperconjugated, vinylogous variant of acidolysis. The objective of this paper is to provide a plausible supramolecular basis for mitigation and rescue from well-known environmental toxicity represented by the presence of sodium fluoride, aluminum salts, and silicofluoride species in public water supplies. An overview of the conceptual basis for NGTC by vitamin C during inflammatory states is provided. Controversies concerning the initial oxidation steps and pH-dependent speciation of L-ascorbic acid are addressed. Non-skeletal fluorosis is a serious systemic malady which we propose arises from disruption of hydrogen bond networks and hydrogen bond cooperativity resulting from the marked electronegativity and hydrogen bond accepting ability of fluoride atoms found in NaF and AlFx species. AlFx species have been previously shown to arise in situ spontaneously from NaF, aluminum salts, and silicofluorides often found in toothpastes and “fluoridated” drinking water. AlFx species are thought to act as isosteric mimics of biophosphates during group transfers of phosphoryl moieties. We propose that catalytic mimicry by AlFx species inhibits postulated non-enzymatic kinase-like and RNA polymerase-like function of the AA-2P derivative during inflammatory states. We describe how NGTC by L-ascorbic acid is likely to be disrupted by AlFx and sodium fluoride of a specific H3-O2 intramolecular hydrogen bond in L-ascorbic acid, the L-ascorbic acid free radical, and their 2-O-substituted derivatives, which are necessary for NGTC in the moderately acidic, mildly oxidative, relatively hydrophobic microenvironment which typify inflammatory states. Suggestions are made to achieve less variation in results of large randomized clinical trials (RCTs) seeking to validate use of high-dose intravenous vitamin C in critical care and cancer settings.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"4 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117034200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global financial patterns and pronouncements point to a seismic overhaul of governance and financial systems that is playing out beneath the surface of the Covid-19 pandemic, reaching far beyond the health domain. Increased centralized control has the potential to create an unbridgeable chasm between a tiny handful of winners and a majority of losers. To foster an integrated analysis of the technocratic and financial forces and agendas at play, this rapid review identifies some of the pandemic’s principal beneficiaries across the interwoven financial, tech, biopharmaceutical, and military-intelligence sectors, assessing developments in the context of the accelerating global push for technocratic consolidation and control. The evidence suggests that Trojan horse coronavirus vaccines may challenge bodily integrity and informed consent in entirely new ways, transporting invasive technologies into people’s brains and bodies. Technologies such as brain-machine interfaces, digital identity tracking devices, and cryptocurrency-compatible chips would contribute to the central banking goal of replacing currencies with digital transaction and identification systems and creating a global control grid that connects the world population to the military-pharma-intelligence cloud of the global technocrats. Moreover, using vaccines as a delivery vehicle for surveillance technologies cancels any legal liability.
{"title":"Planned Surveillance and Control by Global Technocrats: A Big-Picture Look at the Current Pandemic Beneficiaries","authors":"Children's Health Defense Team","doi":"10.56098/ijvtpr.v1i2.7","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.7","url":null,"abstract":"Global financial patterns and pronouncements point to a seismic overhaul of governance and financial systems that is playing out beneath the surface of the Covid-19 pandemic, reaching far beyond the health domain. Increased centralized control has the potential to create an unbridgeable chasm between a tiny handful of winners and a majority of losers. To foster an integrated analysis of the technocratic and financial forces and agendas at play, this rapid review identifies some of the pandemic’s principal beneficiaries across the interwoven financial, tech, biopharmaceutical, and military-intelligence sectors, assessing developments in the context of the accelerating global push for technocratic consolidation and control. The evidence suggests that Trojan horse coronavirus vaccines may challenge bodily integrity and informed consent in entirely new ways, transporting invasive technologies into people’s brains and bodies. Technologies such as brain-machine interfaces, digital identity tracking devices, and cryptocurrency-compatible chips would contribute to the central banking goal of replacing currencies with digital transaction and identification systems and creating a global control grid that connects the world population to the military-pharma-intelligence cloud of the global technocrats. Moreover, using vaccines as a delivery vehicle for surveillance technologies cancels any legal liability.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131827475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A hyperimmune state secondary to dysregulation of the immune system during lower pulmonary viral infections, sepsis and in some cases non-infectious disorders, is now considered to be the principle event leading to clinical deterioration and eventual death in these patients. While most studies have attributed the pathological damage to the lung to be primarily due to high levels of cytokines and chemokines along with massive infiltration of principally neutrophils and macrophages, there is compelling evidence that overactivation of glutamate receptors is also playing a significant, if not critical role in this process. Functional glutamate receptors, along with two important glutamate transport systems, have now been described in epithelial and endothelial cells in the pulmonary airways as well as all involved immune cells. Experimental studies using cytokine models have shown considerable protection against pathological damage to pulmonary tissues by reducing the activation of these glutamate receptors.
{"title":"Excitotoxicity (Immunoexcitotoxicity) as a Critical Component of the Cytokine Storm Reaction in Pulmonary Viral Infections, Including SARS-Cov-2","authors":"R. L. Blaylock","doi":"10.56098/ijvtpr.v1i2.14","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.14","url":null,"abstract":"A hyperimmune state secondary to dysregulation of the immune system during lower pulmonary viral infections, sepsis and in some cases non-infectious disorders, is now considered to be the principle event leading to clinical deterioration and eventual death in these patients. While most studies have attributed the pathological damage to the lung to be primarily due to high levels of cytokines and chemokines along with massive infiltration of principally neutrophils and macrophages, there is compelling evidence that overactivation of glutamate receptors is also playing a significant, if not critical role in this process. Functional glutamate receptors, along with two important glutamate transport systems, have now been described in epithelial and endothelial cells in the pulmonary airways as well as all involved immune cells. Experimental studies using cytokine models have shown considerable protection against pathological damage to pulmonary tissues by reducing the activation of these glutamate receptors.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115326648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this article, I give some of the history of COVID-19, and review some of the unanswered questions about what is being represented as an extraordinary “pandemic”. Foremost among them is whether those “fashioning the narrative”, to borrow a phrase from the Stanford mathematician Richard Moore, also had a hand in fashioning the “pandemic” itself. I also introduce the articles in the rest of this issue that follow my own.
{"title":"The Age of COVID-19: Fear, Loathing, and the “New Normal”","authors":"Christopher A. Shaw","doi":"10.56098/ijvtpr.v1i2.11","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.11","url":null,"abstract":"In this article, I give some of the history of COVID-19, and review some of the unanswered questions about what is being represented as an extraordinary “pandemic”. Foremost among them is whether those “fashioning the narrative”, to borrow a phrase from the Stanford mathematician Richard Moore, also had a hand in fashioning the “pandemic” itself. I also introduce the articles in the rest of this issue that follow my own.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121305837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This review zeros in on the aspect of vaccine theory, practice, and research that is the most dangerous, the most controversial, and that is at the epicenter of the alleged SARS-CoV-2 “pandemic”. Regardless whether the “pandemic” itself is real or an illusion manufactured out of fear by vested interests, it is central to ethics and policy discussions seeking to understand bioweapons research in general. The official involvement of the USA in civilian bioweapons research dates at least from World War II under President Franklin Delano Roosevelt. The historical records, cloaked in secrecy until after the Anthrax mailing of 2001, reveal an intimate connection to vaccine research and development, its governmental protection from public scrutiny, and from citizen initiated lawsuits. It is an industry that has released dangerous weaponized pathogens by accident and by sinister designs supposedly compensated in the peace-loving nations by unrealistic hopes in non-existent counter-measures for outbreaks, including epidemiological tracking after the fact, vaccines being researched to counter the weaponization of pathogens being studied, immunity enhancing drugs, and downstream hoped for blood sera containing antibodies. Critical questions concern the ratio of real-risks to hoped-for-benefits, the “mitigating” measures “governments” (especially in the USA) have supposedly established to prevent pandemic outbreaks from bioweapons research, and how all that has played out in the instance of SARS-CoV-2.
{"title":"Weaponized Pathogens and the SARS-CoV-2 Pandemic","authors":"John W. Oller, Jr.","doi":"10.56098/ijvtpr.v1i2.16","DOIUrl":"https://doi.org/10.56098/ijvtpr.v1i2.16","url":null,"abstract":"This review zeros in on the aspect of vaccine theory, practice, and research that is the most dangerous, the most controversial, and that is at the epicenter of the alleged SARS-CoV-2 “pandemic”. Regardless whether the “pandemic” itself is real or an illusion manufactured out of fear by vested interests, it is central to ethics and policy discussions seeking to understand bioweapons research in general. The official involvement of the USA in civilian bioweapons research dates at least from World War II under President Franklin Delano Roosevelt. The historical records, cloaked in secrecy until after the Anthrax mailing of 2001, reveal an intimate connection to vaccine research and development, its governmental protection from public scrutiny, and from citizen initiated lawsuits. It is an industry that has released dangerous weaponized pathogens by accident and by sinister designs supposedly compensated in the peace-loving nations by unrealistic hopes in non-existent counter-measures for outbreaks, including epidemiological tracking after the fact, vaccines being researched to counter the weaponization of pathogens being studied, immunity enhancing drugs, and downstream hoped for blood sera containing antibodies. Critical questions concern the ratio of real-risks to hoped-for-benefits, the “mitigating” measures “governments” (especially in the USA) have supposedly established to prevent pandemic outbreaks from bioweapons research, and how all that has played out in the instance of SARS-CoV-2.","PeriodicalId":391540,"journal":{"name":"International Journal of Vaccine Theory, Practice, and Research","volume":"17 11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134139728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}