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Machine Learning in Health Care: Ethical Considerations Tied to Privacy, Interpretability, and Bias 医疗保健中的机器学习:与隐私、可解释性和偏见相关的伦理考虑因素
Q2 Medicine Pub Date : 2024-07-11 DOI: 10.18043/001c.120562
Thomas Hofweber, Rebecca L. Walker
Machine learning models hold great promise with medical applications, but also give rise to a series of ethical challenges. In this survey we focus on training data, model interpretability and bias and the related issues tied to privacy, autonomy, and health equity.
机器学习模型在医疗应用中大有可为,但也带来了一系列伦理挑战。在本调查中,我们将重点关注训练数据、模型的可解释性和偏差,以及与隐私、自主性和健康公平相关的问题。
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引用次数: 1
Sarcoidosis Mortality in North Carolina: Role of Region, Race, and Other Sociodemographic Variables 北卡罗来纳州肉样瘤病死亡率:地区、种族和其他社会人口变量的作用
Q2 Medicine Pub Date : 2024-06-05 DOI: 10.18043/001c.118578
D. Wambui, Gregory Kearney, Kevin O'Brien, Guy Iverson, Ogugua Ndili Obi
There is regional variability in sarcoidosis mortality across the United States. North Carolina ranks highly in sarcoidosis-related mortality, especially among African Americans (AA). We sought to determine any regional variability of sarcoidosis-related mortality and the relationship to sociodemographic determinants of health in North Carolina. Counties in North Carolina were categorized into three distinct geographic regions: Western, Piedmont, and Eastern. Sarcoidosis deaths were stratified by region, race, and gender. We conducted a mapping and cluster analysis utilizing ArcGIS; Global and Local Moran’s I was used to determine the prevalence, spatial autocorrelation, and clustering of mortality vis-a-vis various sociodemographic variables, occupational/environmental exposures, and levels of atmospheric particulate matter less than 2.5 microns in size (PM2.5). Multivariate linear regression with exposure limited to the county level was used to determine the relationship between sarcoidosis mortality and the variables of interest. Eastern North Carolina (ENC) had the highest age-adjusted sarcoidosis mortality rate (1.16/100,000 versus 0.49/100,000 in Piedmont and 0.32/100,000 in the Western region) with statistically significant high-high mortality clusters (P < .001 for Global Moran’s I). Several sociodemographic and occupational factors (proportion of AA, obese adults, and individuals working in nature) were more prevalent in ENC. Region and proportion of AA were the significant mortality predictors in our multivariate analysis. This was a cross-sectional study with exposure limited to the county level. Associations do not imply causality and risks cannot be extrapolated to the individual level. There is regional variability of sarcoidosis mortality in North Carolina. Eastern North Carolina had the highest mortality with high-high mortality clusters.
美国各地的肉样瘤病死亡率存在地区差异。北卡罗来纳州的肉样瘤病相关死亡率居高不下,尤其是非裔美国人(AA)。我们试图确定北卡罗来纳州肉样瘤病相关死亡率的地区差异以及与社会人口健康决定因素的关系。北卡罗来纳州的县被分为三个不同的地理区域:西部、皮德蒙特和东部。肉样瘤病死亡人数按地区、种族和性别进行了分层。我们利用 ArcGIS 进行了绘图和聚类分析;使用全局和局部莫兰 I 来确定死亡率与各种社会人口变量、职业/环境暴露以及小于 2.5 微米的大气颗粒物(PM2.5)水平之间的流行率、空间自相关性和聚类关系。为了确定肉样瘤病死亡率与相关变量之间的关系,我们采用了多变量线性回归法,并将暴露限制在县一级。北卡罗来纳州东部(ENC)的年龄调整后肉样瘤病死率最高(1.16/100,000,而皮德蒙特地区为 0.49/100,000,西部地区为 0.32/100,000),并存在统计学意义上的高死亡率集群(全球莫兰 I 值 P < .001)。一些社会人口和职业因素(AA 比例、肥胖成年人和在自然界工作的个人)在 ENC 中更为普遍。在我们的多变量分析中,地区和 AA 比例是重要的死亡率预测因素。这是一项横断面研究,研究对象仅限于县一级。关联并不意味着因果关系,风险也不能推断到个人层面。北卡罗来纳州的肉样瘤病死亡率存在地区差异。北卡罗来纳州东部的死亡率最高,有高死亡率集群。
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引用次数: 0
Health Needs and Priorities of an Underserved Karenni Refugee Community: A Community Needs Assessment 服务不足的克伦尼难民社区的健康需求和优先事项:社区需求评估
Q2 Medicine Pub Date : 2024-06-05 DOI: 10.18043/001c.118583
Ana D Sucaldito, Htay Meh, Scott D. Rhodes, Stephanie S. Daniel
Southeast Asian refugee communities are frequently underserved by social and medical systems and experience profound health and health care inequities. The purpose of this study was to detail the health needs, priorities, and health care utilization of the Karenni, a Southeast Asian refugee community, in Forsyth County, North Carolina. A mixed-mode survey (i.e., online and in-person) was distributed in Kayah, Burmese, and English to Karenni adults in Forsyth County. Quantitative and qualitative questions focused on community health needs, health and public health service utilization, and social determinants of health. 101 Karenni adults completed the survey, with a total of 91 participants completing the quantitative portion (N = 91). Utilization of health care and public health services was low and impacted by individual- and contextual-level barriers, such as limited English profi­ciency and social determinants of health (e.g., lower levels of education and employment compared to state and national averages). Mental health, chronic pain, and health care access were highlighted as prominent community concerns while theh plaw theh jie (togetherness) and community organizations were described as community strengths. Data were collected using convenience sampling, and limited knowledge from the Karenni community regarding research served as a barrier to recruitment. Some sensitive questions (e.g., income) also experienced higher levels of missingness. This assessment highlights the need to increase engagement with and lower barriers to care for the Karenni community in Forsyth County, North Carolina. To produce culturally congruent and acceptable care, public health and health care systems should partner with the community to identify and address community needs and priorities, harness assets, and mitigate health and health care inequities.
东南亚难民社区往往得不到社会和医疗系统的充分服务,在健康和医疗保健方面存在严重的不平等。本研究旨在详细了解北卡罗来纳州福塞斯县东南亚难民社区克伦尼人的健康需求、优先事项和医疗保健利用情况。研究人员用克耶语、缅甸语和英语向福塞斯县的克伦尼族成年人发放了一份混合模式调查问卷(即在线调查和面对面调查)。定量和定性问题主要涉及社区健康需求、健康和公共卫生服务利用情况以及健康的社会决定因素。101 名克伦尼族成年人完成了调查,共有 91 名参与者完成了定量部分(N = 91)。医疗保健和公共卫生服务的利用率较低,并受到个人和环境层面障碍的影响,如英语水平有限和健康的社会决定因素(例如,与州和全国平均水平相比,教育和就业水平较低)。心理健康、慢性疼痛和获得医疗保健服务是社区关注的突出问题,而 "团结"(theh plaw theh jie)和社区组织则被描述为社区的优势。数据收集采用便利抽样法,克伦尼社区对研究的了解有限,这成为招募工作的障碍。一些敏感问题(如收入)的遗漏率也较高。这项评估强调了提高北卡罗来纳州福塞斯县卡伦尼族社区参与度和降低护理障碍的必要性。为了提供与文化相符且可接受的医疗服务,公共卫生和医疗保健系统应与社区合作,确定并解决社区的需求和优先事项,利用资产,并减少健康和医疗保健方面的不平等。
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引用次数: 0
Endemic La Crosse Virus Neuroinvasive Disease in North Carolina Residents: 2000–2020 北卡罗来纳州居民中流行的拉克罗斯病毒神经侵入性疾病:2000-2020
Q2 Medicine Pub Date : 2024-06-05 DOI: 10.18043/001c.118585
Joseph Davis, Chelsea Atkins, Michael S. Doyle, Carl J Williams, Ross Boyce, Brian D. Byrd
La Crosse virus neuroinvasive disease (LACVND) is the most common cause of arboviral encephalitis in children within the United States; in North Carolina, it is the most prevalent endemic mosquito-borne disease in humans. Here we report a surveillance summary of confirmed and probable LACVND during 2000–2020 using North Carolina Electronic Disease Surveillance System data, and we describe associated demographic characteristics, spatiotemporal distribution, clinical features, and mortality rates. A total of 355 cases (74.9% confirmed) were reported from 41 North Carolina counties; most cases (92%) occurred in 19 Western North Carolina counties. An average of 17 cases were reported annually with the majority (94%) of cases occurring between mid-June and early October (epiweeks 25–41). The median case age was nine years (range: 1–95 years), 79% were aged ≤ 18 years, and 56.6% were male. Cases commonly presented with headache (95.4%), fever (95.1%), and altered mental status (80.8%); encephalitis (82.0%) and meningitis (45.9%) were frequently diagnosed. Encephalitis was more common in children (87%) than adults (62%) (P < .001). Similarly, seizures were more common in children (54%) than adults (27%) (P < .01). The case fatality rate was 1.4%; however, differences in age-specific rates were observed. Changes in case definitions and reporting requirements, missing data, different reporting sources, and the retrospective nature of this study are all important limitations of our study. Given the persistent endemicity of La Crosse virus in Western North Carolina, clinicians and public health providers should consider La Crosse virus disease in all individuals, especially children, with compatible symptoms and a travel history to endemic counties. Prevention measures and educational outreach/public health messaging should focus on caregivers and children in Western North Carolina counties and during times when transmission risk is higher (i.e., summer and early fall).
拉克罗斯病毒性神经侵袭病(LACVND)是美国儿童中最常见的虫媒病毒性脑炎病因;在北卡罗来纳州,它是人类中最流行的蚊媒地方病。在此,我们利用北卡罗来纳州电子疾病监测系统的数据,报告了 2000-2020 年期间确诊和疑似 LACVND 的监测总结,并描述了相关的人口特征、时空分布、临床特征和死亡率。北卡罗来纳州 41 个县共报告了 355 例病例(74.9% 为确诊病例);大多数病例(92%)发生在北卡罗来纳州西部的 19 个县。每年平均报告 17 例病例,大多数病例(94%)发生在 6 月中旬至 10 月初(第 25-41 周)。病例年龄中位数为 9 岁(范围:1-95 岁),79% 的病例年龄小于 18 岁,56.6% 为男性。病例通常表现为头痛(95.4%)、发热(95.1%)和精神状态改变(80.8%);脑炎(82.0%)和脑膜炎(45.9%)是常见的诊断病症。脑炎在儿童中的发病率(87%)高于成人(62%)(P < .001)。同样,癫痫发作在儿童中的发病率(54%)也高于成人(27%)(P < .01)。病例死亡率为 1.4%,但不同年龄段的病例死亡率存在差异。病例定义和报告要求的变化、数据缺失、不同的报告来源以及本研究的回顾性质都是我们研究的重要局限性。鉴于拉克罗斯病毒在北卡罗来纳州西部的持续流行,临床医生和公共卫生服务提供者应考虑对所有有相应症状和流行县旅行史的人,尤其是儿童,进行拉克罗斯病毒疾病的筛查。预防措施和教育宣传/公共卫生信息应重点关注北卡罗来纳州西部各县的护理人员和儿童以及传播风险较高的时期(如夏季和初秋)。
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引用次数: 0
New IPEC Competencies, the State of the Science, and a Focus on Equity 消除童工现象国际计划的新能力、科学现状和对公平的关注
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117090
Diana McNeill, Paige Brown
From the value of team-based patient care to the focus on the learner, the 2023 Interprofessional Education Collaborative Core Competencies include a more succinct approach to collaborative care. We review the changes and note their potential impacts on collaborative practice.
从基于团队的患者护理的价值到对学习者的关注,2023 年跨专业教育合作核心能力包括了一种更简洁的合作护理方法。我们回顾了这些变化,并指出其对协作实践的潜在影响。
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引用次数: 0
Developing Preceptors to Teach in an Interprofessional Practice 培养跨专业实践教学的实习生
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117224
Philip T. Rodgers
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引用次数: 1
Retailers’ Compliance with Federal Age of Cigarette Sales Policies – Pitt County, North Carolina, January–March 2022 零售商遵守联邦卷烟销售年龄政策的情况 - 北卡罗来纳州皮特县,2022 年 1-3 月
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117074
Joseph G. L. Lee, Mahdi Sesay, Judy van de Venne, Amanda Y. Kong, M. Hrywna, Shyanika W. Rose, C. Delnevo
Tobacco use remains a leading cause of preventable morbidity and premature mortality. In December 2019, the federal age of sale for tobacco products increased from age 18 to age 21. This study aimed to evaluate the implementation of federal Tobacco 21 policies in Pitt County, North Carolina, by conducting multiple purchase attempts for cigarettes. Stores in Pitt County that sold cigarettes were randomly sampled and visited by up to six different underage buyers (aged 18–20 years) who attempted to buy cigarettes from January to March 2022. Buyers made a total of 217 cigarette purchase attempts from 49 Pitt County retailers. Analyses were conducted using SPSS Complex Samples (v.28/Macintosh) to estimate retailer prevalence of requesting identification (ID) and selling to underage buyers across multiple purchase attempts. On average, retailers failed to request ID in 15.4% of purchase attempts (95% CI; 9.4%–21.3%) and sold to an underage buyer 34.2% of the time (95% CI; 27.0%–41.4%). Additionally, 75.5% (95% CI; 63.4%–84.6%) of retailers sold to an underage buyer at least once. This study is limited to a single county in North Carolina and to underage buyers aged 18 to 20 years. There is widespread noncompliance with federal age-of-sale policies for tobacco products in Pitt County, North Carolina. State enforcement is warranted, and North Carolina’s youth access law should be amended to match the federal age of sale. Changes to the law should allow research involving underage purchases.
烟草使用仍然是可预防的发病和过早死亡的主要原因。2019 年 12 月,联邦规定的烟草产品销售年龄从 18 岁提高到 21 岁。本研究旨在通过多次尝试购买卷烟,评估联邦 21 岁烟草政策在北卡罗来纳州皮特县的实施情况。在 2022 年 1 月至 3 月期间,皮特县销售香烟的商店被随机取样,并有多达六名不同的未成年买家(18-20 岁)到访,试图购买香烟。买家在皮特县 49 家零售商处共尝试购买了 217 支香烟。我们使用 SPSS Complex Samples(v.28/Macintosh)进行了分析,以估算零售商在多次购买尝试中要求未成年买家提供身份证明(ID)和向未成年买家出售卷烟的普遍程度。平均而言,在 15.4% 的购买尝试中(95% CI;9.4%-21.3%),零售商未要求买家出示身份证件;在 34.2% 的购买尝试中(95% CI;27.0%-41.4%),零售商向未成年买家出售商品。此外,75.5%(95% CI;63.4%-84.6%)的零售商至少向未成年买家出售过一次。本研究仅限于北卡罗来纳州的一个县以及 18 至 20 岁的未成年买家。北卡罗来纳州皮特县普遍存在不遵守联邦烟草制品销售年龄政策的情况。北卡罗来纳州的青少年获取烟草制品的法律应予以修订,以符合联邦规定的销售年龄。法律的修改应允许涉及未成年人购买的研究。
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引用次数: 0
Transforming Health Care Delivery: Innovations in Payment Models for Interprofessional Team-Based Care 改革医疗服务:跨专业团队护理的支付模式创新
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117089
Hossein Khalili
By examining the strengths, limitations, and implications of different payment models we seek to inform policymakers, practitioners, and educators on the path toward patient-cen­tered, efficient, and sustainable primary health care deliv­ery. Health care payment model reform should be viewed as an investment in future health asset capacity and equity production rather than an immediate return on investment for short-term health care cost reduction.
通过研究不同支付模式的优势、局限性和影响,我们试图为政策制定者、从业人员和教育工作者提供信息,帮助他们走上以患者为中心、高效且可持续的初级医疗服务之路。医疗支付模式改革应被视为对未来医疗资产能力和公平生产的投资,而非短期降低医疗成本的即时投资回报。
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引用次数: 1
“It Takes a Village”- A Conversation with the Interprofessional Diabetes Clinic at the ECU Health Family Medicine Center "这需要一个村庄"--与 ECU 健康家庭医学中心跨专业糖尿病诊所的对话
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117227
Christine Lysaght, J. Messenger, Shiv Patil, Kay Craven
Interprofessional collaboration and shared understanding positively impact both patients and providers. Current recommendations from the CDC and experts agree that collaboration between diverse professions is necessary to improve patient outcomes and empower patients to selfmanage their chronic conditions.
跨专业合作和共同理解对患者和医疗服务提供者都有积极影响。疾病预防控制中心目前的建议和专家们一致认为,不同专业之间的合作对于改善患者的治疗效果和增强患者自我管理慢性病的能力非常必要。
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引用次数: 1
Assessing Interprofessional Collaboration at Clinical Learning Sites: Methodology on Developing the IP-CLEAR Tool 评估临床学习场所的跨专业合作:开发 IP-CLEAR 工具的方法
Q2 Medicine Pub Date : 2024-05-07 DOI: 10.18043/001c.117219
Kimberly A. Sanders, Mary R. Lynn
Interprofessional Clinical Learning Environment Assessment and Reflection (IP-CLEAR) tool was developed by a team of faculty from the schools of nursing, pharmacy, and medicine at University of North Carolina at Chapel Hill (UNC-CH), with the support of the North Carolina Area Health Education Consortium (NC AHEC) and the UNC-CH Office of Interprofessional Education and Practice (IPEP). The IP-CLEAR tool is intended for use by clinical sites that have or want to have clinical learners engaged and integrated into an excellent interprofessional CLE. The development of the IP-CLEAR and projections for future work are described here.
跨专业临床学习环境评估与反思(IP-CLEAR)工具由北卡罗来纳大学教堂山分校(UNC-CH)护理学院、药学院和医学院的教师团队开发,并得到了北卡罗来纳州地区健康教育联盟(NC AHEC)和北卡罗来纳大学教堂山分校跨专业教育与实践办公室(IPEP)的支持。IP-CLEAR 工具旨在供已经或希望让临床学习者参与并融入优秀的跨专业 CLE 的临床机构使用。本文介绍了 IP-CLEAR 的开发过程以及对未来工作的预测。
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引用次数: 1
期刊
North Carolina Medical Journal
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